CN104027857A - Tray device and blood irradiator - Google Patents
Tray device and blood irradiator Download PDFInfo
- Publication number
- CN104027857A CN104027857A CN201410175105.0A CN201410175105A CN104027857A CN 104027857 A CN104027857 A CN 104027857A CN 201410175105 A CN201410175105 A CN 201410175105A CN 104027857 A CN104027857 A CN 104027857A
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- pallet
- blood
- rotating shaft
- source
- driving wheel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides a tray device, comprising a rotating shaft, a tray for holding blood products and a driving mechanism, wherein the tray is rotationally arranged on the rotating shaft, and the driving mechanism comprises a connecting rod connected with the tray and a driving wheel for driving the connecting rod to further drive the tray to rotate around the rotating shaft. By using the tray device, the position of blood at the middle of the blood product can be exchanged with these at the upper and lower surfaces of the blood product by the rotating tray, so that radiation uniformity of the blood product can be improved, and thus the volume of the blood product in once radiation can be increased, and efficiency of the blood radiator can be improved. Furthermore, the invention provides a blood radiator.
Description
Technical field
The present invention relates to medical apparatus and instruments field, relate in particular to a kind of pallet apparatus and blood irradiator that improves blood products irradiation uniformity.
Background technology
Transfusion-associated graft versus host disease (TA-GVHD) is that immunodeficiency or immunosuppressant patient can not remove input and have immunocompetent lymphocyte in blood, it is planted in vivo and live, breed, patient's histoorgan is identified as to non-own material, and as target, carries out a kind of mortality complication of blood transfusion of immune attack, destruction.TA-GVHD clinical manifestation lacks specificity, very easily fails to pinpoint a disease in diagnosis and mistaken diagnosis.
There are some researches show that the receptor input lymphocyte quantity that causes TA-GVHD should be greater than 107/kg, if can not cause TA-GVHD lower than 105/kg.But have report to the child of immunodeficiency only 104/kg lymphocyte cause TA-GVHD.More its state of an illness of lymphocyte quantity of inputting in a word donor are more serious, and mortality rate is also just higher.
Thinking at present before blood transfusion blood product is irradiated, is to prevent the only effective method of TA-GVHD.Its mechanism is: lymphocyte, to radiation-sensitive, by the roentgenization of suitable dosage, can make immunocompetent lymphocytes deactivation, loses multiplication capacity.And it is little on erythrocyte, hematoblastic function and coagulation factor activity impact.Developed country's utility ratio has reached 30%～40% now.
Blood irradiator is exactly a kind of use roentgenization blood products, and lymphocyte is carried out to deactivation, the armarium of TA-GVHD disease in prevention blood transfusion activity.
From radiographic source, divide, blood irradiator can be divided into two classes, and a class is the radiation gamma blood products that adopts radioactive source (being mainly Cs-137) to produce; Another kind of is the x-ray bombardment blood products that adopts X-ray tube to produce.Wherein, radioactive source type blood irradiator need to assemble hundreds of to the isotope radioactive source of upper kilocurie, and this exists potential nuclear leakage risk.X source type blood irradiator does not have the risk of nuclear leakage, and equipment one power-off just produces without any ray.
But, there is the inhomogeneous shortcoming of low, the single source of X ray energy irradiation in X source type blood irradiator, can not meet in blood irradiator standard the requirement of uniformity of radiation (GB requires the heterogeneity <20% of blood irradiator irradiation).The X-ray energy that common X source produces is generally below 200keV, and it is easy to be absorbed in a large number by the blood of shallow-layer in irradiation of blood goods process, and the X-ray quantum count that arrives depths is reduced rapidly.And the isotope radioactive source of radioactive source type blood irradiator assembling is generally Cs-137 and Co-60, the γ photon energy that they are emitted is respectively 662keV, 1.17MeV and 1.33MeV.The energy of these γ photons is far away higher than the energy of X-ray, and its linear attenuation coefficient in blood products will be much smaller than X-ray, so the irradiation uniformity in its single source will be far superior to X source, as depicted in figs. 1 and 2.
In order to overcome the shortcoming of single source irradiation, industry has proposed the scheme of double source irradiation, by respectively placing an X source at the upper and lower both direction of blood products, can significantly improve the uniformity of irradiation, as shown in Figure 3 and Figure 4.
Although two X source schemes have solved the homogeneity question of single X source irradiation, the thickness of radiation exposed blood products or volume are still limited.If blood products is too thick or X ray energy is on the low side, the difference of the dosage at blood products center and the dosage of upper and lower surface still can be greater than 20% so, and as shown in Figure 5, this has just limited the work efficiency of X source type blood irradiator.
Summary of the invention
In view of this, the object of this invention is to provide a kind of pallet apparatus and blood irradiator that improves blood products irradiation uniformity.
A pallet apparatus, the pallet that it comprises rotating shaft and holds blood products, described pallet is rotatably arranged at described rotating shaft.
In the present invention's one better embodiment, described pallet two ends are arranged at described rotating shaft symmetrically.
A kind of pallet apparatus, it comprises rotating shaft, holds pallet and the driving mechanism of blood products, described pallet is rotatably arranged at described rotating shaft, and described driving mechanism comprises the driving wheel that connects the connecting rod of described pallet and drive described connecting rod to drive described pallet to rotate around described rotating shaft.
In the present invention's one better embodiment, also comprise the motor that drives described driving wheel rotation.
In the present invention's one better embodiment, described connecting rod has relative first end and the second end, described first end is articulated with described pallet, described the second end with respect to the rotating shaft eccentric of described driving wheel be articulated with described driving wheel, and the jointed shaft of described first end, the jointed shaft of described the second end and the rotating shaft of described driving wheel are all parallel to described rotating shaft.
In the present invention's one better embodiment, described pallet two ends are arranged at described rotating shaft symmetrically.
In the present invention's one better embodiment, described first end is articulated with one end of described pallet.
In the present invention's one better embodiment, described the second end is articulated with the marginal area of described driving wheel.
The present invention also provides a kind of blood irradiator, and it comprises the radiographic source of pallet apparatus and radiation blood goods as mentioned above.
In the present invention's one better embodiment, described radiographic source is single source X source or double source X source.
Compared to prior art, pallet apparatus provided by the invention and blood irradiator tool have the following advantages: utilize rotating pallet can allow the blood occurrence positions of the middle blood of blood products and upper and lower surface exchange, can improve the uniformity of blood products irradiation, and then can increase the volume of blood products in single irradiation, improve the efficiency of blood irradiator.
Above-mentioned explanation is only the general introduction of technical solution of the present invention, in order to better understand technological means of the present invention, and can be implemented according to the content of description, and for above and other objects of the present invention, feature and advantage can be become apparent, below especially exemplified by embodiment, and coordinate accompanying drawing, be described in detail as follows.
Accompanying drawing explanation
Fig. 1 is prior art list X source radiation blood goods schematic diagrams;
When Fig. 2 is prior art list X source radiation blood goods, different-energy X ray is at the energy deposition curve chart of the different blood degree of depth;
Fig. 3 is the two X source radiation blood goods schematic diagrams of prior art;
When Fig. 4 is the two X source radiation blood goods of prior art, different-energy X ray is at the energy deposition curve chart of the different blood degree of depth;
Energy deposition curve chart when Fig. 5 is the two X source irradiation 150mm thickness blood products of prior art;
The schematic diagram of the pallet apparatus that Fig. 6 provides for first embodiment of the invention;
Fig. 7 is a kind of working state schematic representation of pallet apparatus shown in Fig. 6;
The schematic diagram of the pallet apparatus that Fig. 8 provides for second embodiment of the invention;
Fig. 9 is a kind of working state schematic representation of pallet apparatus shown in Fig. 8;
The schematic diagram of the blood irradiator that Figure 10 provides for third embodiment of the invention.
The specific embodiment
Below in conjunction with drawings and the specific embodiments, the present invention is further detailed explanation.
Refer to Fig. 6, first embodiment of the invention provides a kind of pallet apparatus 100, and it can improve the irradiation uniformity of blood products, and described pallet apparatus 100 comprises rotating shaft 10 and hold the pallet 20 of blood products, and described pallet 20 is rotatably arranged at described rotating shaft 10.
Preferably, described pallet 20 two ends are arranged at described rotating shaft 10 symmetrically, i.e. described rotating shaft 10 is positioned at the zone line of described pallet 20, that is described pallet 20 two ends are arranged at described rotating shaft 10 evenly.
During use, first blood products is contained in to described pallet 20, and is placed in the irradiation zone of X source; Then open X source and carry out irradiation, in blood products irradiation process, controlling described pallet 20 rotates within the scope of certain angle around described rotating shaft 10, as shown in Figure 7, by making, accommodate the container front and back of blood products or vacillate now to the left, now to the right, and then make the blood flow in container, allow the blood of the interior diverse location of container mutually exchange, lymphocyte in blood can fully be irradiated, realize by the middle blood of blood products and the blood occurrence positions of upper and lower surface are exchanged, improve the uniformity of blood products irradiation.
Be understandable that, control angular range and rotational frequency that described pallet 20 rotates around described rotating shaft 10, can control the speed of the blood occurrence positions exchange of the middle blood of blood products and upper and lower surface, and then control the efficiency of blood products irradiation.
Refer to Fig. 8, second embodiment of the invention provides a kind of pallet apparatus 200, it can improve the irradiation uniformity of blood products, described pallet apparatus 200 comprises rotating shaft 10, holds pallet 20 and the driving mechanism 30 of blood products, described pallet 20 is rotatably arranged at described rotating shaft 10, described driving mechanism 30 comprises connecting rod 31 and driving wheel 33, and described connecting rod 31 connects described pallet 20, and described driving wheel 33 drives described connecting rod 31 to drive described pallet 20 to rotate around described rotating shaft 10.
In the present embodiment, the two ends of described connecting rod 31 are articulated with respectively described pallet 20 and described driving wheel 33, particularly, described connecting rod 31 has relative first end 311 and the second end 313, described first end 311 is articulated with described pallet 20, described the second end 313 is articulated with described driving wheel 33 prejudicially with respect to the rotating shaft 331 of described driving wheel 33, and the jointed shaft 315 of described first end 311 is, the rotating shaft 331 of the jointed shaft 317 of described the second end 313 and described driving wheel 33 is all parallel to described rotating shaft 10.
Preferably, described pallet 20 two ends are arranged at described rotating shaft 10 symmetrically, i.e. described rotating shaft 10 is positioned at the zone line of described pallet 20, that is described pallet 20 two ends are arranged at described rotating shaft 10 evenly.The first end 311 of described connecting rod 31 is articulated with one end of described pallet 20, and the second end 313 of described connecting rod 31 is articulated with the marginal area of described driving wheel 33.
During use, first blood products is contained in to described pallet 20, and is placed in the irradiation zone of X source; Then open X source and carry out irradiation, in blood products irradiation process, by described driving wheel 33, can control described pallet 20 rotates within the scope of certain angle around described rotating shaft 10, as shown in Figure 9, and then can make the blood occurrence positions of the middle blood of blood products and upper and lower surface exchange, improve the uniformity of blood products irradiation.
Further, described pallet apparatus 200 also comprises the motor (not shown) that drives described driving wheel 33 rotations, can realize thus the described driving wheel 33 of automatic control.
Refer to Figure 10, third embodiment of the invention provides a kind of blood irradiator 300, and it comprises radiographic source 50 and the described pallet apparatus 200 (or pallet apparatus 100) of radiation blood goods.
In the present embodiment, described radiographic source 50 is X source, is understandable that, described radiographic source 50 can be single source X source or double source X source.
Compared to prior art, pallet apparatus 100 provided by the invention (with pallet apparatus 200) and blood irradiator 300 tools have the following advantages: utilize rotating pallet 10 can allow the blood occurrence positions of the middle blood of blood products and upper and lower surface exchange, can improve the uniformity of blood products irradiation, and then can increase the volume of blood products in single irradiation, improve the efficiency of blood irradiator.
The above, only embodiments of the invention, not the present invention is done to any pro forma restriction, although the present invention discloses as above with embodiment, yet not in order to limit the present invention, any those skilled in the art, do not departing within the scope of technical solution of the present invention, when can utilizing the technology contents of above-mentioned announcement to make a little change or being modified to the equivalent embodiment of equivalent variations, in every case be not depart from technical solution of the present invention content, any simple modification of above embodiment being done according to technical spirit of the present invention, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.
Claims (10)
1. a pallet apparatus, is characterized in that, described pallet apparatus comprises rotating shaft and hold the pallet of blood products, and described pallet is rotatably arranged at described rotating shaft.
2. pallet apparatus as claimed in claim 1, is characterized in that, described pallet two ends are arranged at described rotating shaft symmetrically.
3. a pallet apparatus, it is characterized in that, described pallet apparatus comprises rotating shaft, holds pallet and the driving mechanism of blood products, described pallet is rotatably arranged at described rotating shaft, and described driving mechanism comprises the driving wheel that connects the connecting rod of described pallet and drive described connecting rod to drive described pallet to rotate around described rotating shaft.
4. pallet apparatus as claimed in claim 3, is characterized in that, also comprises the motor that drives described driving wheel rotation.
5. pallet apparatus as claimed in claim 3, it is characterized in that, described connecting rod has relative first end and the second end, described first end is articulated with described pallet, described the second end with respect to the rotating shaft eccentric of described driving wheel be articulated with described driving wheel, and the jointed shaft of described first end, the jointed shaft of described the second end and the rotating shaft of described driving wheel are all parallel to described rotating shaft.
6. pallet apparatus as claimed in claim 5, is characterized in that, described pallet two ends are arranged at described rotating shaft symmetrically.
7. pallet apparatus as claimed in claim 6, is characterized in that, described first end is articulated with one end of described pallet.
8. pallet apparatus as claimed in claim 5, is characterized in that, described the second end is articulated with the marginal area of described driving wheel.
9. a blood irradiator, is characterized in that, comprises pallet apparatus as described in claim 1～7 any one and the radiographic source of radiation blood goods.
10. blood irradiator as claimed in claim 9, is characterized in that, described radiographic source is single source X source or double source X source.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410175105.0A CN104027857A (en) | 2014-04-28 | 2014-04-28 | Tray device and blood irradiator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410175105.0A CN104027857A (en) | 2014-04-28 | 2014-04-28 | Tray device and blood irradiator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104027857A true CN104027857A (en) | 2014-09-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410175105.0A Pending CN104027857A (en) | 2014-04-28 | 2014-04-28 | Tray device and blood irradiator |
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| Country | Link |
|---|---|
| CN (1) | CN104027857A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104307060A (en) * | 2014-10-22 | 2015-01-28 | 中国科学院苏州生物医学工程技术研究所 | X-ray blood irradiator |
| CN104324425A (en) * | 2014-10-17 | 2015-02-04 | 中国科学院苏州生物医学工程技术研究所 | Blood irradiation instrument |
| WO2017016085A1 (en) * | 2015-07-24 | 2017-02-02 | 江苏摩科特医疗科技有限公司 | Single x-ray source blood irradiation device and irradiation method thereof |
| CN110237322A (en) * | 2019-06-27 | 2019-09-17 | 江苏同威信达技术有限公司 | Double source X-ray blood irradiator and its operating method |
| CN110237322B (en) * | 2019-06-27 | 2024-05-24 | 同威信达技术(江苏)股份有限公司 | Dual-source X-ray blood irradiation instrument and operation method thereof |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1986000823A1 (en) * | 1984-07-24 | 1986-02-13 | Peter Unger | A method and apparatus for taking blood |
| CN2221978Y (en) * | 1994-06-10 | 1996-03-13 | 上海希格玛高技术公司 | Multi-function ultraviolet irradiation treatment device |
| CN2225252Y (en) * | 1995-08-29 | 1996-04-24 | 上海希格玛高技术公司 | Ultra-violet irradiator for treating blood platelet |
| CN2492231Y (en) * | 2000-11-20 | 2002-05-22 | 北京京精医疗设备有限公司 | Autoblood recovering machine |
| CN2720445Y (en) * | 2003-09-29 | 2005-08-24 | 邓冠华 | Shaking-up device for venous blood sample |
| CN1695745A (en) * | 2004-05-13 | 2005-11-16 | 苏华 | Blood treatment device for treating microcirculatory disturbance |
| CN200991448Y (en) * | 2006-12-28 | 2007-12-19 | 中国核动力研究设计院 | Blood radiometer central dose rate regulation mechanism |
| CN201194806Y (en) * | 2008-04-28 | 2009-02-18 | 赵代军 | Liquid taking mixed instrument |
| CN201481884U (en) * | 2009-08-19 | 2010-05-26 | 张青云 | Medical high oxygen quantum purifier for blood |
-
2014
- 2014-04-28 CN CN201410175105.0A patent/CN104027857A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1986000823A1 (en) * | 1984-07-24 | 1986-02-13 | Peter Unger | A method and apparatus for taking blood |
| CN2221978Y (en) * | 1994-06-10 | 1996-03-13 | 上海希格玛高技术公司 | Multi-function ultraviolet irradiation treatment device |
| CN2225252Y (en) * | 1995-08-29 | 1996-04-24 | 上海希格玛高技术公司 | Ultra-violet irradiator for treating blood platelet |
| CN2492231Y (en) * | 2000-11-20 | 2002-05-22 | 北京京精医疗设备有限公司 | Autoblood recovering machine |
| CN2720445Y (en) * | 2003-09-29 | 2005-08-24 | 邓冠华 | Shaking-up device for venous blood sample |
| CN1695745A (en) * | 2004-05-13 | 2005-11-16 | 苏华 | Blood treatment device for treating microcirculatory disturbance |
| CN200991448Y (en) * | 2006-12-28 | 2007-12-19 | 中国核动力研究设计院 | Blood radiometer central dose rate regulation mechanism |
| CN201194806Y (en) * | 2008-04-28 | 2009-02-18 | 赵代军 | Liquid taking mixed instrument |
| CN201481884U (en) * | 2009-08-19 | 2010-05-26 | 张青云 | Medical high oxygen quantum purifier for blood |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104324425A (en) * | 2014-10-17 | 2015-02-04 | 中国科学院苏州生物医学工程技术研究所 | Blood irradiation instrument |
| CN104307060A (en) * | 2014-10-22 | 2015-01-28 | 中国科学院苏州生物医学工程技术研究所 | X-ray blood irradiator |
| WO2017016085A1 (en) * | 2015-07-24 | 2017-02-02 | 江苏摩科特医疗科技有限公司 | Single x-ray source blood irradiation device and irradiation method thereof |
| CN110237322A (en) * | 2019-06-27 | 2019-09-17 | 江苏同威信达技术有限公司 | Double source X-ray blood irradiator and its operating method |
| CN110237322B (en) * | 2019-06-27 | 2024-05-24 | 同威信达技术(江苏)股份有限公司 | Dual-source X-ray blood irradiation instrument and operation method thereof |
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Application publication date: 20140910 |