CN205073369U - Blood irradiator - Google Patents
Blood irradiator Download PDFInfo
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- CN205073369U CN205073369U CN201520680354.5U CN201520680354U CN205073369U CN 205073369 U CN205073369 U CN 205073369U CN 201520680354 U CN201520680354 U CN 201520680354U CN 205073369 U CN205073369 U CN 205073369U
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Abstract
The utility model provides a blood irradiator, it includes that a X ray source, a plurality of being used for place the container of blood or goods and drive each the container is the driver of rotation independently, a plurality of container rings wind X ray source interval sets up, and each the container average level to the X ray source. Blood irradiator passes through each independently rotation of container of loading blood or goods that the driver driving ring wound the X ray source, can improve the utilization efficiency of the X ray of X ray source transmission effectively. Simultaneously, positive and negative through each container in turn the transform can fully improve the homogeneity of blood or goods irradiation towards the X ray source. In addition, through control each container positive and negative in turn the transform accept X X -ray irradiation, under the condition of guaranteeing the irradiation homogeneity, can shorten time of single irradiation, reduced the energy consumption (the work energy consumption of X -ray tube and cooling system's heat dissipation energy consumption) of single irradiation to the operation cost of equipment has finally been reduced.
Description
Technical field
This utility model relates to technical field of medical instruments, particularly relates to a kind of blood irradiator of single x-ray source.
Background technology
Transfusion-associated graft versus host disease (TA-GVHD) be immunodeficiency or immunosuppressant patient can not remove input blood in there is immunocompetent lymphocyte, it is made to plant alive, propagation in vivo, the histoorgan of patient is identified as non-own material, and carries out a kind of mortality complication of blood transfusion of immune attack, destruction as target.TA-GVHD clinical manifestation lacks specificity, very easily fails to pinpoint a disease in diagnosis and mistaken diagnosis.
There are some researches show that causing the receptor of TA-GVHD to input lymphocyte quantity should be greater than 10
7/ kg, if lower than 10
5/ kg then can not cause TA-GVHD.But there is report to the child of immunodeficiency only 10
4namely/kg lymphocyte causes TA-GVHD.Lymphocyte quantity its state of an illness more inputting donor are in a word more serious, and mortality rate is also higher.
Thinking at present and irradiate blood product before transfusing blood, is the only effective method of prevention TA-GVHD.Its mechanism is: lymphocyte, to radiation-sensitive, by the roentgenization of suitable dosage, can make immunocompetent lymphocytes deactivation, loses multiplication capacity.And it is little on the impact of erythrocyte, hematoblastic function and coagulation factor activity.Present developed country utility ratio reaches 30% ~ 40%.
Blood irradiator is exactly a kind of use roentgenization blood or goods, carries out deactivation to lymphocyte, the armarium of TA-GVHD disease (transfusion-associated graft versus host disease) in prevention blood transfusion activity.
Divide from radiographic source, blood irradiator can be divided into two classes, and a class is the gamma-rays irradiation of blood or goods that adopt radioactive source (mainly Cs-137) to produce; Another kind of is the x-ray bombardment blood or goods that adopt X-ray tube to produce.Wherein, radioactive source type blood irradiator equipment needs to assemble the isotope radioactive source of hundreds of to upper kilocurie, and this also exists potential nuclear leakage risk.X source type blood irradiator does not then have the risk of nuclear leakage, and device powers down just produces without any ray.
But, there is the uneven shortcoming of X-ray energy low, single source irradiation in X source type blood irradiator, is difficult to meet the requirement (the heterogeneity <20% of Standard blood irradiator irradiation) to uniformity of radiation in blood irradiator standard.The X-ray energy that common X source produces is generally at below 200keV, and it is in irradiation of blood or goods process, is easy to be absorbed in a large number by the blood of shallow-layer, and the X-ray quantum count arriving depths is reduced rapidly.And the isotope radioactive source of radioactive source type blood irradiator assembling is generally Cs-137 and Co-60, the γ photon energy that they are released is 662keV, 1.17MeV and 1.33MeV respectively.The energy of these γ photons is far away higher than the energy of X-ray, and its linear attenuation coefficient in blood or goods will much smaller than X-ray, so the irradiation uniformity in its single source will be far superior to X source, as depicted in figs. 1 and 2.
In order to overcome the shortcoming of single source irradiation, industry proposes the scheme of double source irradiation, by respectively placing an X source at blood or the upper and lower both direction of goods, can significantly improve the uniformity of irradiation, as shown in Figure 3 and Figure 4.
Although two X source scheme solves the homogeneity question of single X source irradiation, this scheme needs two cover x-ray source systems, and the cost of system is multiplied.In order to reduce system cost, ensure the uniformity of x-ray irradiation, a kind of single source X-ray blood irradiator design has newly been carried in the Chinese patent application of CN201410550120.9 out simultaneously.The program utilizes the position of cavity in turntable rotation to move, and the upper and lower surface achieving blood bag is alternately irradiated.As shown in Figure 5, such as in the position of 1, X-ray is incident below blood bag, forwards the position of 3 to, just becomes incident above blood bag.Like this, with the irradiation equivalent of double source scheme, but exposure time is forced to extend at double.
Known, although the scheme in CN201410550120 makes complete machine only need a set of x-ray source system, reduce the cost of blood irradiator, the X-ray utilization rate of the program is still lower, and exposure time is multiplied, the operation cost of X-ray blood irradiator will be caused to increase.
We know, in X-ray tube, high energy electron bombardment anode produces in the process of X-ray, the energy of more than 99% will change into heat, these heats not only to irradiation without any contribution, but also need cooling system it to be taken out of from anode, otherwise X-ray tube can damage.In the scheme of CN201410550120, blood or goods arrive the process of 3 from 1 through 2, due to the restriction in space, blood or goods can not become an annulus by close-packed arrays, many X-ray are escaped from the upper and lower of blood or goods, this makes the utilization rate of X-ray obviously on the low side, and then has directly had influence on the power consumption of blood irradiator, irradiation time and illumination efficiency.
Utility model content
Based on this, this utility model provides a kind of blood irradiator, effectively to solve prior art Problems existing.
A kind of blood irradiator, it driver comprising an x-ray source, multiple container for placing blood or goods and drive container described in each independently to rotate, described multiple container ring is arranged around described x-ray source interval, and container described in each is all towards described x-ray source.
Relative to prior art, described blood irradiator is independently rotated around each loading blood of x-ray source or the container of goods by driver drives, effectively can improve the utilization ratio of the X-ray that x-ray source is launched.Meanwhile, by the positive and negative checker of each container towards x-ray source, the uniformity of blood or goods irradiation can fully be improved.In addition, x-ray irradiation is accepted by controlling each container positive and negative checker, under the condition ensureing irradiation uniformity, the time of single irradiation can be shortened, reduce the energy consumption (operating power consumption of X-ray tube and the radiation energy consumption of cooling system) of single irradiation, thus eventually reduce the operation cost of equipment.
In this utility model one better embodiment, described driver drives container described in each clockwise or be rotated counterclockwise.
In this utility model one better embodiment, container described in each includes internal layer and skin, that described internal layer and described skin form scalable distance each other jointly and only allow the interlayer of placement one bag of blood or goods.Thus, by controlling the distance between the internal layer of described container and skin, the thickness of blood or goods can be controlled, reduces the heterogeneity of internal layer and superficies radiation dose.
In this utility model one better embodiment, in the surface normal of container described in each and described x-ray source, the angle of the axis of X-ray tube is 0 ~ 90 degree.
In this utility model one better embodiment, described driver is electric rotating machine, it drives container described in each independently to rotate by a drive mechanism, described drive mechanism comprises a driving pulley, , a Timing Belt, a driven pulley, a driving gear and multiple driven gear, described driving pulley is sheathed on the main shaft of described electric rotating machine, and realize V belt translation by described Timing Belt and the cooperation of described driven pulley, described driven pulley and described driving gear are fixedly installed on same rotating shaft, described multiple driven gear is connected by universal joint correspondingly with described multiple container, and be all meshed with described driving gear, described driving gear and driven gear described in each are fixed-axis rotation.
In this utility model one better embodiment, described multiple driven gear is arranged around described driving gear interval.
In this utility model one better embodiment, one end of described universal joint connects the rotating shaft of corresponding described driven gear, and the other end connects the rotating shaft of corresponding described container, has an angle between the rotating shaft of the rotating shaft of described driven gear and the described container of correspondence.
In this utility model one better embodiment, also comprise a loading plate, the main shaft of described driver is arranged at described loading plate by a bearing.
In this utility model one better embodiment, also comprise the hollow fixed axis that is fixedly installed on described loading plate, described hollow fixed axis fixes the X-ray tube of described x-ray source away from one end of described loading plate.
In this utility model one better embodiment, the rotating shaft of described driven pulley is rotatably sheathed on described hollow fixed axis by a bearing.
In this utility model one better embodiment, also comprise and provide the high voltage power supply of electric energy for described x-ray source and described driver and carry out the heat abstractor that dispels the heat for described blood irradiator.
In this utility model one better embodiment, also comprise the dose monitoring device of the irradiation dose of monitoring of blood or goods.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of prior art list X source radiation blood goods;
When Fig. 2 is prior art list X source radiation blood goods, different-energy X-ray is at the energy deposition curve chart of the different blood degree of depth;
Schematic diagram when Fig. 3 is prior art two X source radiation blood goods;
When Fig. 4 is prior art two X source radiation blood goods, different-energy X-ray is at the energy deposition curve chart of the different blood degree of depth;
Fig. 5 be position that prior art utilizes cavity in turntable rotation move realize blood bag upper and lower surface by the schematic diagram alternately irradiated;
The overall schematic of the blood irradiator that Fig. 6 provides for this utility model one preferred embodiment;
Fig. 7 is the enlarged diagram of region VII-VII in blood irradiator shown in Fig. 6;
Fig. 8 realizes the schematic diagram of each container positive and negative checker towards x-ray source for blood irradiator shown in Fig. 6.
Detailed description of the invention
For the ease of understanding this utility model, below with reference to relevant drawings, this utility model is described more fully.Better embodiment of the present utility model is given in accompanying drawing.These are only preferred embodiment of the present utility model; not thereby the scope of the claims of the present utility model is limited; every utilize this utility model description and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present utility model.
Unless otherwise defined, all technology used herein and scientific terminology are identical with belonging to the implication that those skilled in the art of the present utility model understand usually.The object of the term used in description of the present utility model herein just in order to describe concrete embodiment, is not intended to be restriction this utility model.Term as used herein " and/or " comprise arbitrary and all combinations of one or more relevant Listed Items.
See also Fig. 6 and Fig. 7, this utility model one preferred embodiment provides a kind of blood irradiator, it comprises an x-ray source 10, multiple container 20 for placing blood or goods and drives the independent driver 30 rotated of container 20 described in each, described multiple container 20 is arranged around described x-ray source 10 interval, and container 20 described in each is all towards described x-ray source.
Be understandable that, described x-ray source 10 has the X-ray tube launching X-ray.
In the present embodiment, container 20 described in each includes internal layer 21 and outer 23, and described internal layer 21 and described outer 23 is oppositely arranged, common form scalable distance each other and only allow the interlayer of placement one bag of blood or goods.Thus, by controlling the distance between the internal layer 21 of described container 20 and outer 23, the thickness of blood or goods can be controlled, reduces the heterogeneity of internal layer 21 and outer 23 surface emissivity dosage.
Preferably, in the surface normal of container 20 described in each and described x-ray source 10, the angle of the axis of X-ray tube is 0 ~ 90 degree.Thus, described container 20 can be made to accept the surface of x-ray irradiation towards described x-ray source 10, and described in scalable, container 20 accept the area of x-ray irradiation.
In the present embodiment, described driver 30 drives container 20 described in each clockwise or be rotated counterclockwise.Particularly, described driver 30 is electric rotating machine, it is driven by a drive mechanism 40, and container 20 described in each is independent to be rotated, described drive mechanism 40 comprises a driving pulley 41, , a Timing Belt 42, a driven pulley 43, a driving gear 44 and multiple driven gear 45, described driving pulley 41 is sheathed on the main shaft 31 of described electric rotating machine, and realize V belt translation by described Timing Belt 42 and described driven pulley 43 cooperation, described driven pulley 43 and described driving gear 44 are fixedly installed on same rotating shaft 46, described multiple driven gear 45 is connected by universal joint 50 correspondingly with described multiple container 20, and be all meshed with described driving gear 44.
When described driver 30 works, described driving pulley 41 is driven to rotate by its main shaft 31; Described driving pulley 41 drives described driven pulley 43 to rotate by described Timing Belt 42, and realizes V belt translation; Because described driving gear 44 and described driven pulley 43 are fixedly installed on rotating shaft 46, therefore, the rotation of described driven pulley 43 will drive described driving gear 44 to rotate; Described driving gear 44 drives the described multiple driven gears 45 engaged with it to rotate further; Driven gear 45 described in each by described universal joint 50 by power transmission to corresponding described container 20, and finally realize that container 20 described in each is independent to be rotated.
In the present embodiment, power transmission is realized by the mode of V belt translation between described driver 30 and described driving gear 44, be understandable that, be not limited thereto, between described driver 30 and described driving gear 44, also can realize power transmission by chaindriven mode or gear-driven mode.Particularly, when adopting Chain conveyer, correspondingly driving pulley 41 and driven pulley 43 are replaced with sprocket wheel, and described Timing Belt 42 is replaced with chain.And when adopting gear drive, driving pulley 41 is replaced with driven wheel and itself and described driving gear 44 are engaged, certainly, between driven wheel and described driving gear 44, also power transmission can be realized by idler gear.As long as described driver 30 can effectively drive container 20 described in each independently to rotate.
In the present embodiment, described driving gear 44 and driven gear 45 described in each are fixed-axis rotation, and namely described driving gear 44 and the rotating shaft of driven gear 45 described in each all maintain static.
Preferably, described multiple driven gear 45 is arranged around described driving gear 44 interval.Particularly, described multiple driven gear 45 is arranged at the side of a bucking ladder 60 by its rotating shaft, the center of described bucking ladder 60 and the axis coaxle of described x-ray source.Be understandable that, the quantity of described driven gear 45 can be arranged according to actual needs, as five, six or other quantity.
In the present embodiment, one end of described universal joint 50 connects the rotating shaft of corresponding described driven gear 45, and the other end connects the rotating shaft of corresponding described container 20, has an angle between the rotating shaft of the rotating shaft of described driven gear 45 and the described container 20 of correspondence.
In the present embodiment, described blood irradiator also comprises a loading plate 70, and the main shaft 31 of described driver 30 is arranged at described loading plate 70 by a bearing 33.
Further, described blood irradiator also comprises the hollow fixed axis 80 that is fixedly installed on described loading plate 70, and described hollow fixed axis 80 fixes the X-ray tube of described x-ray source 10 away from one end of described loading plate 70.The rotating shaft (i.e. the rotating shaft of described driving gear 44) of described driven pulley 43 is rotatably sheathed on described hollow fixed axis 80 by a bearing (figure does not indicate).Thus, the power transmission of described driver 30 and described drive mechanism 40 can effectively be realized.
Be understandable that, described blood irradiator also comprises for described x-ray source 10 and described driver 30 provide the high voltage power supply 90 of electric energy, carry out dose monitoring device 94 and the control system 96 of the irradiation dose of heat abstractor 92, monitoring of blood or the goods dispelled the heat for described blood irradiator.In the present embodiment, described dose monitoring device 94 is arranged at the side of described container 20.Described control system 96 is for controlling described high voltage power supply 90, described heat abstractor 92 and described dose monitoring device 94.
The groundwork process of described blood irradiator is as follows: blood or goods are placed in the interlayer of each container 20, and each container 20 all has one facing to x-ray source 10, and x-ray source 10 is started working, normal exposure.After irradiating a period of time, each container 20, under the driving effect of driver 30, revolves turnback by universal joint, makes other one facing to x-ray source 10.Then hocket, until the radiation dose value that dose monitoring device 94 is monitored reaches predetermined value, x-ray source 10 is closed, and irradiation terminates.
Refer to Fig. 8, blood bag is under the effect of container 20, and positive and negative can alternately towards x-ray source 10, and such as the 1st minute, the A of each container 20 was facing to x-ray source 10; 2nd minute, the B of each container 20 was facing to x-ray source 10; 3rd minute is again that A is facing to x-ray source 10 ..., cycle alternation, thus can be more even by the irradiation making blood or goods be subject to.
Relative to prior art, described blood irradiator, by driver 30 driving ring each loading blood around x-ray source 10 or the independent rotation of container 20 of goods, can improve the utilization ratio of the X-ray that x-ray source 10 is launched effectively.Meanwhile, by the positive and negative checker of each container 20 towards x-ray source 10, the uniformity of blood or goods irradiation can fully be improved.In addition, x-ray irradiation is accepted by controlling each container 20 positive and negative checker, under the condition ensureing irradiation uniformity, the time of single irradiation can be shortened, reduce the energy consumption (operating power consumption of X-ray tube and the radiation energy consumption of cooling system) of single irradiation, thus eventually reduce the operation cost of equipment.
The above embodiment only have expressed several embodiment of the present utility model, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to this utility model the scope of the claims.It should be pointed out that for the person of ordinary skill of the art, without departing from the concept of the premise utility, can also make some distortion and improvement, these all belong to protection domain of the present utility model.Therefore, the protection domain of this utility model patent should be as the criterion with claims.
Claims (12)
1. a blood irradiator, it is characterized in that, the driver comprising an x-ray source, multiple container for placing blood or goods and drive container described in each independently to rotate, described multiple container ring is arranged around described x-ray source interval, and container described in each is all towards described x-ray source.
2. blood irradiator as claimed in claim 1, is characterized in that, described driver drives container described in each clockwise or be rotated counterclockwise.
3. blood irradiator as claimed in claim 1, it is characterized in that, container described in each includes internal layer and skin, that described internal layer and described skin form scalable distance each other jointly and only allow the interlayer of placement one bag of blood or goods.
4. blood irradiator as claimed in claim 1, is characterized in that, in the surface normal of container described in each and described x-ray source, the angle of the axis of X-ray tube is 0 ~ 90 degree.
5. blood irradiator as claimed in claim 1, it is characterized in that, described driver is electric rotating machine, it drives container described in each independently to rotate by a drive mechanism, described drive mechanism comprises a driving pulley, , a Timing Belt, a driven pulley, a driving gear and multiple driven gear, described driving pulley is sheathed on the main shaft of described electric rotating machine, and realize V belt translation by described Timing Belt and the cooperation of described driven pulley, described driven pulley and described driving gear are fixedly installed on same rotating shaft, described multiple driven gear is connected by universal joint correspondingly with described multiple container, and be all meshed with described driving gear, described driving gear and driven gear described in each are fixed-axis rotation.
6. blood irradiator as claimed in claim 5, it is characterized in that, described multiple driven gear is arranged around described driving gear interval.
7. blood irradiator as claimed in claim 5, it is characterized in that, one end of described universal joint connects the rotating shaft of corresponding described driven gear, and the other end connects the rotating shaft of corresponding described container, has an angle between the rotating shaft of the rotating shaft of described driven gear and the described container of correspondence.
8. blood irradiator as claimed in claim 5, it is characterized in that, also comprise a loading plate, the main shaft of described driver is arranged at described loading plate by a bearing.
9. blood irradiator as claimed in claim 5, is characterized in that, also comprise the hollow fixed axis that is fixedly installed on described loading plate, and described hollow fixed axis fixes the X-ray tube of described x-ray source away from one end of described loading plate.
10. blood irradiator as claimed in claim 9, it is characterized in that, the rotating shaft of described driven pulley is rotatably sheathed on described hollow fixed axis by a bearing.
11. blood irradiators as claimed in claim 1, is characterized in that, also comprise and provide the high voltage power supply of electric energy for described x-ray source and described driver and carry out the heat abstractor that dispels the heat for described blood irradiator.
12. blood irradiators as claimed in claim 1, is characterized in that, also comprise the dose monitoring device of the irradiation dose of monitoring of blood or goods.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520680354.5U CN205073369U (en) | 2015-09-06 | 2015-09-06 | Blood irradiator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520680354.5U CN205073369U (en) | 2015-09-06 | 2015-09-06 | Blood irradiator |
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| CN205073369U true CN205073369U (en) | 2016-03-09 |
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| CN201520680354.5U Active CN205073369U (en) | 2015-09-06 | 2015-09-06 | Blood irradiator |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105214152A (en) * | 2015-09-06 | 2016-01-06 | 江苏摩科特医疗科技有限公司 | A kind of blood irradiator |
| CN106139276A (en) * | 2016-07-28 | 2016-11-23 | 江苏摩科特医疗科技有限公司 | X-ray blood irradiation instrument apparatus |
| WO2022116984A1 (en) * | 2020-12-02 | 2022-06-09 | 中国医学科学院输血研究所 | Rotary irradiation apparatus |
| RU227361U1 (en) * | 2023-09-15 | 2024-07-17 | Георгий Борисович Шарков | Blood irradiation device |
-
2015
- 2015-09-06 CN CN201520680354.5U patent/CN205073369U/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105214152A (en) * | 2015-09-06 | 2016-01-06 | 江苏摩科特医疗科技有限公司 | A kind of blood irradiator |
| WO2017035874A1 (en) * | 2015-09-06 | 2017-03-09 | 江苏摩科特医疗科技有限公司 | Blood irradiator |
| CN106139276A (en) * | 2016-07-28 | 2016-11-23 | 江苏摩科特医疗科技有限公司 | X-ray blood irradiation instrument apparatus |
| WO2022116984A1 (en) * | 2020-12-02 | 2022-06-09 | 中国医学科学院输血研究所 | Rotary irradiation apparatus |
| RU227361U1 (en) * | 2023-09-15 | 2024-07-17 | Георгий Борисович Шарков | Blood irradiation device |
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