CN110237322B - Dual-source X-ray blood irradiation instrument and operation method thereof - Google Patents
Dual-source X-ray blood irradiation instrument and operation method thereof Download PDFInfo
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- CN110237322B CN110237322B CN201910567913.4A CN201910567913A CN110237322B CN 110237322 B CN110237322 B CN 110237322B CN 201910567913 A CN201910567913 A CN 201910567913A CN 110237322 B CN110237322 B CN 110237322B
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- 210000004369 blood Anatomy 0.000 title claims abstract description 61
- 239000008280 blood Substances 0.000 title claims abstract description 61
- 238000000034 method Methods 0.000 title claims description 12
- 230000005855 radiation Effects 0.000 claims abstract description 32
- 230000001678 irradiating effect Effects 0.000 claims abstract description 17
- 238000005286 illumination Methods 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims description 27
- 230000009977 dual effect Effects 0.000 claims description 10
- 238000001816 cooling Methods 0.000 claims description 7
- 239000000498 cooling water Substances 0.000 claims description 7
- 239000002184 metal Substances 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 229920000049 Carbon (fiber) Polymers 0.000 claims description 3
- 239000004917 carbon fiber Substances 0.000 claims description 3
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims description 3
- 239000000463 material Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 7
- 208000021187 Transfusion associated graft versus host disease Diseases 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 230000002285 radioactive effect Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000001772 blood platelet Anatomy 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
- A61M2205/103—General characteristics of the apparatus with powered movement mechanisms rotating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
The invention relates to a dual-source X-ray blood irradiator, comprising: the device comprises a self-shielding radiation irradiating bin, a turntable positioned in the self-shielding radiation irradiating bin, and two X-ray light tubes respectively fixed at the top and bottom of the self-shielding radiation irradiating bin; wherein two of said X-ray tubes are capable of illuminating blood at an illumination station on said turret; and the turntable is rotatable to adjust the amount of radiation at the irradiation station. The double-source X-ray blood irradiator is convenient to realize a good shielding effect on X-rays and well prevent the leakage of the X-rays by arranging the self-shielding irradiation bin; through the arrangement of the turntable, the bearing effect of the blood container can be realized, so that the distance between the two X-ray light tubes positioned at the top and the bottom of the radiation shielding irradiation bin for irradiating blood can be ensured to be equal, and the uniformity of irradiation amount and the irradiation of the dose with the same amount can be ensured conveniently; and rotatable setting of the turntable, is convenient for realizing the adjustment of the dose of blood irradiation.
Description
Technical Field
The invention relates to the field of medical irradiation, in particular to a double-source X-ray blood irradiation instrument and an operation method thereof.
Background
Transfusion of patients with unirradiated blood may cause transfusion-associated graft versus host disease (TA-GVHD), so it is widely recognized in the industry that whole blood, red blood cells, platelets, granulocytes, injected into a high risk group of TA-GVHD must be irradiated.
At present, most of domestic mainstream blood irradiation products are Cs-137 or Co-60, and the problems of radioactive source leakage risk, radioactive source post-treatment and the like exist. The X-ray tube irradiator driven by the high-voltage power supply has no any ray residue after power failure, and the problem of radioactive source treatment does not exist.
The existing X-ray light tube has limited dosage, and the adoption of ultra-high-power single light tube equipment has a series of problems of over-complex system, huge equipment volume, uneven irradiation dosage, over-high technical threshold, over-high use cost and the like.
Disclosure of Invention
The invention aims to solve the technical problems that: a dual-source X-ray blood irradiator with uniform irradiation dose and proper equipment volume is provided.
The technical scheme adopted for solving the technical problems is as follows: a dual source X-ray blood irradiator comprising:
The device comprises a self-shielding radiation irradiating bin, a turntable positioned in the self-shielding radiation irradiating bin, and two X-ray light tubes respectively fixed at the top and bottom of the self-shielding radiation irradiating bin; wherein the method comprises the steps of
Two of the X-ray tubes are capable of illuminating blood at an illumination station on the turret; and
The turntable can be rotated to adjust the irradiance and uniformity at the irradiance station.
Preferably, the irradiation rays of the two X-ray light pipes are collinear.
Preferably, the distance from the top X-ray tube to the upper end face of the turntable is equal to the distance from the bottom X-ray tube to the lower end face of the turntable.
Preferably, the dual-source X-ray blood irradiation instrument further comprises a liquid bearing container;
the liquid bearing container is borne on the rotary table, and the side wall of the liquid bearing container is provided with a metal skin, wherein
The liquid bearing container can enable X-rays of the X-ray tube positioned at the top and the bottom to penetrate.
Preferably, the side wall of the liquid bearing container is provided with a bearing fin part;
the turntable is provided with a plurality of bearing ports; wherein the method comprises the steps of
The liquid bearing container can be clamped in the bearing opening, and the bearing wing parts are attached to the upper end face of the turntable.
Preferably, the dual-source X-ray blood irradiation apparatus further comprises a gantry;
the frame is two-layer, the self-shielding radiation warehouse is located on one side of the upper layer, and the upper layer and the lower layer of the other side are respectively provided with an X-ray high-voltage power supply for providing power for the X-ray light tube.
Preferably, the dual source X-ray blood irradiator further comprises two light pipe cooling water flow temperature meters, each adapted to one of the X-ray light pipes.
Preferably, the dual source X-ray blood irradiator further comprises an external water machine for cooling the X-ray tube.
Preferably, the dual-source X-ray blood irradiation apparatus further comprises a UPS power supply system, wherein
When the external system is powered off, the UPS power supply system can supply power for the external water machine.
Preferably, the turntable has a rotary motor at the bottom thereof, and
The output shaft of the rotating motor is coaxially fixed with the central shaft of the turntable, wherein
The central axis of the turntable is not collinear with the irradiation directions of the two X-ray light pipes.
The double-source X-ray blood irradiation instrument has the beneficial effects that:
1. the self-shielding radiation irradiation bin is convenient to realize a good shielding effect on X rays and well prevent the leakage of the X rays;
2. Through the arrangement of the turntable, the bearing effect of the blood container can be realized, so that the distance between the two X-ray light tubes positioned at the top and the bottom of the radiation shielding irradiation bin for irradiating blood can be ensured to be equal, and the uniformity of irradiation amount and the irradiation of the dose with the same amount can be ensured conveniently; and rotatable setting of the turntable, is convenient for realizing the adjustment of the dose of blood irradiation.
The invention also provides an operation method of the double-source X-ray blood irradiation instrument,
The double-source X-ray blood irradiator comprises a self-shielding radiation irradiation bin, a rotary table positioned in the self-shielding radiation irradiation bin, and two X-ray light tubes respectively fixed at the top and bottom of the self-shielding radiation irradiation bin;
Two of the X-ray tubes irradiate blood at an irradiation station on the turntable; and is composed of
The turntable rotates to adjust the irradiation amount and uniformity at the irradiation station.
The dual-source X-ray blood irradiation instrument has the beneficial effect of being convenient for realizing the adjustment of irradiation quantity and uniformity at an irradiation station.
Drawings
The invention will be further described with reference to the drawings and examples.
FIG. 1 is a schematic diagram of the structure of a self-shielded irradiation magazine of the present invention;
FIG. 2 is a top cross-sectional view of the self-shielded radiant firebox of the present invention;
FIG. 3 is a schematic diagram of a dual source X-ray blood irradiation apparatus according to the present invention;
FIG. 4 is a schematic view of the structure of the liquid-carrying container of the present invention;
In the figure:
a self-shielding radiation irradiation bin 1, a turntable 2 and a bearing port 201;
An X-ray light pipe 3;
A liquid-receiving container 4 for receiving the fin 401;
A frame 5, an X-ray high-voltage power supply 6 and a UPS power supply system 7.
Detailed Description
The invention will now be described in further detail with reference to the accompanying drawings. The drawings are simplified schematic representations which merely illustrate the basic structure of the invention and therefore show only the structures which are relevant to the invention.
Example 1
As shown in fig. 1 to 3, a dual-source X-ray blood irradiator includes: the self-shielding radiation irradiating bin 1, a rotary table 2 positioned in the self-shielding radiation irradiating bin 1, and two X-ray light tubes 3 respectively fixed at the top and bottom of the self-shielding radiation irradiating bin 1; wherein two of said X-ray tubes 3 are capable of irradiating blood at an irradiation station on said turntable 2; and the turntable 2 is rotatable to adjust the dose and uniformity of irradiation at the irradiation station.
Wherein, the self-shielding radiation irradiating bin 1 is provided with a bin gate which can be opened by more than 90 degrees from the front surface so as to put the irradiated blood container into the bin gate, and the bin gate is provided with an electromagnetic lock and a limit switch so as to avoid the danger caused by the fact that the bin gate cannot be completely closed.
Meanwhile, in order to ensure a good shielding effect, a detachable shielding cover is installed at the X-ray tube 3.
The self-shielding radiation irradiation bin 1 is arranged, so that a good shielding effect on X rays is conveniently realized, and leakage of the X rays is well prevented; through the arrangement of the rotary table 2, the bearing effect of the blood container can be realized, so that the distance of the two X-ray light tubes 3 positioned at the top and the bottom of the radiation shielding irradiation bin for irradiating blood can be ensured to be equal, and the uniformity of irradiation amount and the irradiation of the dose with the same amount can be ensured conveniently; and the rotatable arrangement of the turntable 2 facilitates the adjustment of the dose of blood irradiation.
In this embodiment, the irradiation rays of the two X-ray tubes 3 are collinear. And the distance from the X-ray tube 3 at the top to the upper end face of the turntable 2 is equal to the distance from the X-ray tube 3 at the bottom to the lower end face of the turntable 2. The design is to ensure that the upper and lower surfaces of the irradiated blood receive the irradiation with the same uniformity and the same dosage
In this embodiment, the dual-source X-ray blood irradiation apparatus further includes a liquid container 4; the liquid bearing container 4 is carried on the turntable 2, and the side wall of the liquid bearing container 4 is provided with a metal skin, wherein the liquid bearing container 4 can enable X-rays of the X-ray tube 3 positioned at the top and the bottom to penetrate.
And the side wall of the liquid bearing container 4 is provided with a bearing fin 401; the turntable 2 is provided with a plurality of bearing ports 201; wherein the liquid container 4 can be clamped in the bearing port 201, and the bearing fin 401 is attached to the upper end surface of the turntable 2.
Wherein the liquid bearing container 4 is made of carbon fiber, so that the penetrability of rays is improved. The liquid bearing container 4 can also use a metal side skin to reduce the interference of scattered rays, and can also use a metal top cover and a metal bottom surface to improve the transmission uniformity of the rays.
In this embodiment, the dual source X-ray blood irradiation instrument further comprises a gantry 5;
The stand 5 is in two layers, the self-shielding radiation warehouse 1 is positioned on one side of the upper layer, and the upper layer and the lower layer of the other side are respectively provided with an X-ray high-voltage power supply 6 for providing power for the X-ray light tube 3.
Four liftable casters are arranged at the bottom of the frame 5, and after the irradiation instrument moves in place, the casters can be lifted and positioned by a fixed support.
In this embodiment, the dual source X-ray blood irradiator further comprises two light pipe cooling water flow temperature meters, each adapted to one of the X-ray light pipes 3. The design is to monitor the cooling state of the X-ray tube 3 in real time and separately.
In this embodiment, the dual source X-ray blood irradiation apparatus further comprises an external water machine for cooling the X-ray tube 3. The external water machine is only used for cooling the X-ray tube 3.
In this embodiment, the dual-source X-ray blood irradiation apparatus further comprises a UPS power supply system 7, wherein the UPS power supply system 7 is capable of supplying power to the external water machine when the external system is powered off. Ensure that the cooling system is continuously operated for a period of time with lower power after power failure, continuously cool down the X-ray tube 3, and control information is not lost.
In this embodiment, a rotary motor is disposed at the bottom of the turntable 2, and an output shaft of the rotary motor is coaxially fixed to a turntable central axis of the turntable 2, wherein the turntable central axis of the turntable 2 is not collinear with the irradiation directions of the two X-ray tubes 3. The output shaft of the X-ray tube is not concentric with the irradiation direction, and is driven by a rotating motor, so that uniform rotation at different speeds can be realized, and more targeted dosage requirements can be realized by matching with parameter adjustment of the X-ray tube 3. The turntable 2 is made of carbon fiber or metal, and can hollow out an illuminated area of the turntable to improve the dosage. The turntable 2 can hold a plurality of liquid-bearing containers 4.
The working process comprises the following steps:
The irradiated blood is placed in the fluid-carrying container 4. A plurality of liquid-bearing containers 4 are placed on the respective bearing ports 201 of the turntable 2, respectively. Closing the self-shielding irradiation bin gate and starting the electromagnetic lock of the bin gate. And (5) switching on cooling water and a power supply. The irradiation program is set through the operation panel, and the X-ray tube 3 and the turntable 2 are started to irradiate the blood.
The irradiation procedure is roughly divided into continuous irradiation of a single liquid-bearing container 4 and cyclic irradiation of all liquid-bearing containers 4. The continuous irradiation to the single liquid bearing container 4 needs to ensure that the liquid bearing container 4 stays at the center position of the top-bottom correlation light source, and meanwhile, the double X-ray light tube 3 is started for continuous irradiation, so that the single container has higher efficiency and more accurate dosage. The circulating irradiation of all liquid bearing containers 4 needs continuous uniform motion of the horizontal turntable 2 eccentric to the rays, and meanwhile, the double X-ray light tube 3 is started to continuously irradiate, so that the yield is higher, and the uniformity of the rays is better.
When some equipment in the double-source X-ray blood irradiation instrument needs to be debugged or maintained, the corresponding panel is opened, and the equipment can be debugged or maintained.
When the self-shielding irradiation bin gate and the split type panels with the safety interlocks are not closed, the equipment cannot work. When the cooling water temperature flow rate of the X-ray tube 3 is abnormal, the apparatus cannot work. When the device is suddenly powered off during operation, the cooling water is still supplied for a period of time.
The double-source X-ray blood irradiator can move through the lifting caster, and the double-source X-ray blood irradiator can be supported and fixed when the caster is lifted.
Example two
The second embodiment is based on the first embodiment.
The invention also provides an operation method of the double-source X-ray blood irradiation instrument,
The double-source X-ray blood irradiator comprises a self-shielding radiation irradiation bin 1, a rotary table 2 positioned in the self-shielding radiation irradiation bin 1, and two X-ray light tubes 3 respectively fixed at the top and bottom of the self-shielding radiation irradiation bin 1;
two of the X-ray tubes 3 irradiate blood at an irradiation station on the turntable; and is composed of
The turntable 2 rotates to adjust the irradiation dose and uniformity at the irradiation station.
The dual-source X-ray blood irradiation instrument has the beneficial effect of being convenient for realizing the adjustment of irradiation quantity and uniformity at an irradiation station.
With the above-described preferred embodiments according to the present invention as an illustration, the above-described descriptions can be used by persons skilled in the relevant art to make various changes and modifications without departing from the scope of the technical idea of the present invention. The technical scope of the present invention is not limited to the description, but must be determined according to the scope of claims.
Claims (3)
1. A dual source X-ray blood irradiator comprising:
The device comprises a self-shielding radiation irradiating bin, a turntable positioned in the self-shielding radiation irradiating bin, and two X-ray light tubes respectively fixed at the top and bottom of the self-shielding radiation irradiating bin; wherein the method comprises the steps of
Two of the X-ray tubes are capable of illuminating blood at an illumination station on the turret; the turntable can rotate to adjust the irradiation amount and uniformity at the irradiation station;
the irradiation rays of the two X-ray light pipes are collinear;
The distance from the top X-ray tube to the upper end face of the turntable is equal to the distance from the bottom X-ray tube to the lower end face of the turntable;
the dual-source X-ray blood irradiator also comprises a liquid bearing container;
the liquid-bearing container is borne on the turntable, wherein
The liquid bearing container is made of carbon fiber materials, so that X rays of the X-ray light tube positioned at the top and the bottom can penetrate;
The side wall of the liquid bearing container is provided with a bearing fin part, and the side wall of the liquid bearing container is provided with a metal skin;
the turntable is provided with a plurality of bearing ports; wherein the method comprises the steps of
The liquid bearing container can be clamped in the bearing opening, and the bearing wing part is attached to the upper end face of the turntable;
The bottom of the turntable is provided with a rotating motor, and
The output shaft of the rotating motor is coaxially fixed with the central shaft of the turntable, wherein
The central shaft of the turntable is not collinear with the irradiation directions of the two X-ray light pipes;
The dual-source X-ray blood irradiation instrument further comprises two light pipe cooling water flow temperature meters, and each light pipe cooling water flow temperature meter is matched with one X-ray light pipe; the double-source X-ray blood irradiator also comprises an external water machine for cooling the X-ray tube; the dual-source X-ray blood irradiation instrument further comprises a UPS power supply system, wherein when an external system is powered off, the UPS power supply system can supply power to the external water machine, ensure that a cooling system runs for a period of time with lower power continuously after power off, continuously cool an X-ray light tube, and control information is not lost.
2. The dual source X-ray blood irradiator of claim 1, wherein,
The dual-source X-ray blood irradiator also comprises a stand;
the frame is two-layer, the self-shielding radiation warehouse is located on one side of the upper layer, and the upper layer and the lower layer of the other side are respectively provided with an X-ray high-voltage power supply for providing power for the X-ray light tube.
3. A method of operating a dual source X-ray blood irradiation apparatus according to any one of claims 1 to 2,
The double-source X-ray blood irradiator comprises a self-shielding radiation irradiation bin, a rotary table positioned in the self-shielding radiation irradiation bin, and two X-ray light tubes respectively fixed at the top and bottom of the self-shielding radiation irradiation bin;
Two of the X-ray tubes irradiate blood at an irradiation station on the turntable; and rotated by the turntable to adjust the irradiance and uniformity at the irradiance station.
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