CN1973919B - Cesium-137 radioactive source for blood irradiator - Google Patents
Cesium-137 radioactive source for blood irradiator Download PDFInfo
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- CN1973919B CN1973919B CN2006100707465A CN200610070746A CN1973919B CN 1973919 B CN1973919 B CN 1973919B CN 2006100707465 A CN2006100707465 A CN 2006100707465A CN 200610070746 A CN200610070746 A CN 200610070746A CN 1973919 B CN1973919 B CN 1973919B
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Abstract
The blood irradiator with cesium-137 radioactive source for inactivating immunoactive lymphocyte in blood includes a support body, a support frame, an arc cavity fitting the rotating bench on the support body, a material cavity on the bench, shielding material filled inside the support body and the bench, a driving gear worm pair on the bench, a carrying underpan set in the bottom of the materialcavity and connected to a rotating shaft, a radiation door corresponding to the bench, a cesium-137 radioactive source in a drawer inside the bench and a source vibrator connected to the bottom of thedrawer. The present invention has simple structure, high protecting performance, precise radiation location and optimized dosage control, and can meet the requirement for irradiating blood.
Description
Technical field
The present invention relates to a kind of cesium-137 radioactive source for blood irradiator, be used for deactivation blood and have immunocompetent lymphocyte.
Background technology
Along with deepening continuously of blood transfusion medical research, people progressively recognize the hazardness of transfusional alloimmunity.The blood transfusion untoward reaction that weight does not wait takes place in about according to statistics 2～10% blood transfusion patient.Just have a people among per 800～2500 donees serious transfusion reaction takes place, even threat to life, the dependency graft versus host disease of wherein transfusing blood (TA-GVHD) is exactly one of complication that seriously jeopardizes patient's life security of recognizing in recent years.Think at present the blood transfusion before blood product is shone, be reliable prevention method.
Summary of the invention
The object of the present invention is to provide a kind of cesium-137 radioactive source for blood irradiator, the gamma-rays that utilizes caesium-137 to send, optionally has immunocompetent lymphocyte in the deactivation blood by the control roentgendosis, the generation of prevention blood transfusion dependency graft versus host disease.
Cesium-137 radioactive source for blood irradiator of the present invention, comprise support body and bearing support, support body is provided with the arc-shaped recess cavity that adapts with rotary table, rotary table is provided with material and picks and places cavity, be filled with shielding material in support body and the rotary table inner chamber, the top of rotary table is connected the worm and gear transmission, the bottom that material picks and places cavity is provided with rotation loading chassis, rotation loading chassis is connected in the rotating shaft, pick and place the corresponding irradiation door that is provided with of cavity with the material on the rotary table, pick and place inboard corresponding being provided with of cavity with material on the rotary table and put the radioactive source drawer that cesium-137 radioactive source is arranged, the bottom of radioactive source drawer is connected on the vibrating device of source.
During use, open the irradiation door, the blood material is placed in the loading container, the loading container is placed on the rotation loading chassis, close the irradiation door, rotary table is rotated by the worm and gear transmission, the blood material is delivered to the irradiation position, corresponding with the radioactive source drawer.During irradiation, the blood material rotates under the drive on rotation loading chassis, and simultaneously, the radioactive source drawer moves up and down under the drive of source vibrating device, thereby make lonizing radiation carry out even irradiation, optionally have immunocompetent lymphocyte in the deactivation blood blood.Cesium-137 radioactive source, energy 0.66MVe, 33 years half-life.Rotation loading chassis is driven by rotating shaft, and rotating shaft can directly drive by motor shaft, or drives indirectly by motor shaft and travelling gear, by the control rotating speed of motor, controls the rotating speed on rotation loading chassis, and directly the adapted servomotor is beneficial to automatic control.
Wherein:
The radioactive source drawer is used for encapsulating radioactive source, realizes that the transportation, upside-down mounting of radioactive source and the motion by source drawer realize the motion of radioactive source and resident.The radioactive source drawer comprises that shell and source cup, source are covered, fixed cover, and an end of shell is a link, and the source cup places shell, and the source lid is fixed on the cup of source, and fixed cover covers on the cup of source, and the source cup is fixed.
The shell of radioactive source drawer is cylindric, and travelling performance is good, and the source cup places the middle part of shell, the last hypomere of shell is filled with shielding material, obtains the favorable protection performance, effectively reduces radiant intensity, make irradiator surface leakage close rate be not more than 3 μ Gy/h, reach advanced world standards.
Can in shell, be provided with the radiation hole, the source cup is placed the radiation hole, make things convenient for the replacing of radioactive source.
The source vibrating device comprises splined shaft, spline housing and fixed cover, and spline housing is sleeved on the splined shaft and is fixed in the fixed cover, and the upper end of splined shaft is a radioactive source drawer link, and the lower end of splined shaft connects the ball-screw transmission.
Spline housing has the mobile guide effect to splined shaft, under the driving of ball-screw transmission, makes source drawer realize rectilinear motion, satisfies the irradiation requirement.
The ball-screw transmission connects servomotor by travelling gear, and convenient the realization controlled automatically.Linkage counter on servomotor is realized accurately control by counting.
Cesium-137 radioactive source for blood irradiator of the present invention, simple and reasonable, utilize gamma-rays that cesium-137 radioactive source sends radioactive source as blood irradiation, barrier propterty is good, the irradiation location accurately, by rotary table, can realize the optimization of field dose control, the accuracy and the uniformity control of irradiation dose, satisfy the requirement of blood irradiation.Optionally has immunocompetent lymphocyte in the deactivation blood by the control roentgendosis, the generation of prevention blood transfusion dependency graft versus host disease.
Description of drawings
Fig. 1, one embodiment of the invention structural representation.
The A-A cross section structure sketch map of Fig. 2, Fig. 1.
Fig. 3, radioactive source drawer structure sketch map.
Fig. 4, source vibrating device structural representation.
Among the figure: 1, bearing support 2, housing 3, turbine and worm transmission 4, rotary table 5, loading container 6, radioactive source drawer 7,8, shielding material 9, travelling gear 10, servomotor 11, source vibrating device 12, support body 13, irradiation door 14, rotation loading rotating disk 15, shell 16, fixed cover 17, source lid 18, cesium-137 radioactive source 19, source cup 20, shielding material 21, connector 22, spline housing 23, splined shaft 24, fixed cover 25, servomotor 26, enumerator 27, mounting seat 28, the ball-screw transmission.
The specific embodiment
The invention will be further described in conjunction with the foregoing description accompanying drawing.
As Fig. 1, shown in 2, cesium-137 radioactive source for blood irradiator of the present invention, comprise support body 12 and bearing support 1, support body 12 is provided with the arc-shaped recess cavity that adapts with rotary table, rotary table 4 is provided with material and picks and places cavity, be filled with shielding material 7 respectively in support body 12 and rotary table 4 inner chambers, 8, the top of rotary table 4 is connected worm and gear transmission 3, the bottom that material picks and places cavity is provided with rotation loading chassis 14, rotation loading chassis 14 is connected in the rotating shaft, pick and place the corresponding irradiation door 13 that is provided with of cavity with the material on the rotary table 4, pick and place inboard corresponding being provided with of cavity with material on the rotary table 4 and put the radioactive source drawer 6 that cesium-137 radioactive source is arranged, the bottom of radioactive source drawer 6 is connected on the source vibrating device 11.
As shown in Figure 3, the radioactive source drawer comprises shell 15 and source cup 19, source lid 17, fixed cover 16, cesium-137 radioactive source 18 is placed in the source cup 19, one end of shell 15 is a link, having connector 21 to realize using connects, source cup 19 places shell 15, and source lid 17 is fixed on the source cup 19, and fixed cover 16 covers on the source cup 19.The shell of radioactive source drawer 6 is cylindric, and source cup 19 places the middle part of shell 15, and the last hypomere of shell 15 is filled with shielding material, and shell 15 can be formed the shielding material section at intermediary radioactive source section and two ends by three sections.Can in shell 15, be provided with the radiation hole, source cup 19 is placed the radiation hole, make things convenient for the replacing of source cup 19.
As shown in Figure 4, the source vibrating device comprises splined shaft 23, spline housing 22 and fixed cover 24, spline housing 22 is sleeved on the splined shaft 23 and is fixed in the fixed cover 24, the upper end of splined shaft 23 is a radioactive source drawer link, the lower end of splined shaft 23 connects ball-screw transmission 28, fixed cover 24 grades are installed on the mounting seat 27, and ball-screw transmission 28 connects servomotor 25 by travelling gear, and linkage counter 26 on the servomotor 25.Servomotor 25 directly drives splined shaft 23 by ball-screw transmission 28 again and makes rectilinear motion up and down by the travelling gear transmission, by the counting of enumerator 26, can realize accurate control.
Operation principle:
Worm and gear transmission 3 drives rotary table 4 rotations, and servomotor 10 passes through travelling gear 9 driving rotation loading chassis 14 and rotates, and rectilinear motion formed vibration about ball-screw transmission 28 drove splined shaft 23 works.
Claims (7)
1. cesium-137 radioactive source for blood irradiator, it is characterized in that comprising support body and bearing support, support body is provided with the arc-shaped recess cavity that adapts with rotary table, rotary table is provided with material and picks and places cavity, be filled with shielding material in support body and the rotary table inner chamber, the top of rotary table is connected the worm and gear transmission, the bottom that material picks and places cavity is provided with rotation loading chassis, rotation loading chassis is connected in the rotating shaft, pick and place the corresponding irradiation door that is provided with of cavity with the material on the rotary table, pick and place inboard corresponding being provided with of cavity with material on the rotary table and put the radioactive source drawer that cesium-137 radioactive source is arranged, the bottom of radioactive source drawer is connected on the vibrating device of source.
2. cesium-137 radioactive source for blood irradiator according to claim 1, it is characterized in that the radioactive source drawer comprises that shell and source cup, source are covered, fixed cover, an end of shell is a link, and the source cup places shell, the source lid is fixed on the cup of source, and fixed cover covers on the cup of source.
3. cesium-137 radioactive source for blood irradiator according to claim 2 is characterized in that the shell of radioactive source drawer is cylindric, and the source cup places the middle part of shell, and the last hypomere of shell is filled with shielding material.
4. cesium-137 radioactive source for blood irradiator according to claim 3 is characterized in that being provided with in the shell radiation hole, and the source cup places the radiation hole.
5. according to the described cesium-137 radioactive source for blood irradiator of the arbitrary claim of claim 1-4, it is characterized in that the source vibrating device comprises splined shaft, spline housing and fixed cover, spline housing is sleeved on the splined shaft and is fixed in the fixed cover, the upper end of splined shaft is a radioactive source drawer link, and the lower end of splined shaft connects the ball-screw transmission.
6. cesium-137 radioactive source for blood irradiator according to claim 5 is characterized in that the ball-screw transmission connects servomotor by travelling gear.
7. cesium-137 radioactive source for blood irradiator according to claim 6 is characterized in that linkage counter on the servomotor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006100707465A CN1973919B (en) | 2006-12-14 | 2006-12-14 | Cesium-137 radioactive source for blood irradiator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006100707465A CN1973919B (en) | 2006-12-14 | 2006-12-14 | Cesium-137 radioactive source for blood irradiator |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1973919A CN1973919A (en) | 2007-06-06 |
| CN1973919B true CN1973919B (en) | 2010-06-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006100707465A Expired - Fee Related CN1973919B (en) | 2006-12-14 | 2006-12-14 | Cesium-137 radioactive source for blood irradiator |
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| Country | Link |
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| CN (1) | CN1973919B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103239764A (en) * | 2012-02-09 | 2013-08-14 | 深圳市华科核医疗技术有限公司 | Medical irradiating device |
| CN104324425B (en) * | 2014-10-17 | 2016-08-24 | 中国科学院苏州生物医学工程技术研究所 | A kind of blood irradiator |
| US10381123B1 (en) * | 2016-09-30 | 2019-08-13 | Industrial Heat, Llc | Nuclear excitation transfer via phonon-nuclear coupling |
| CN109524146B (en) * | 2019-01-09 | 2024-05-14 | 同方威视技术股份有限公司 | Radiation irradiation device |
| CN110189848A (en) * | 2019-07-12 | 2019-08-30 | 薛红松 | A kind of small-sized irradiation devices based on californium 252 neutron source |
| CN113198057A (en) * | 2021-06-23 | 2021-08-03 | 重庆建安仪器有限责任公司 | Miniaturized blood irradiation device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992011058A1 (en) * | 1990-12-20 | 1992-07-09 | Baxter International Inc. | Systems and methods eradicating contaminants in fluids |
| US6274100B1 (en) * | 1998-11-05 | 2001-08-14 | J.L. Shepherd & Associated | Process irradiator |
-
2006
- 2006-12-14 CN CN2006100707465A patent/CN1973919B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992011058A1 (en) * | 1990-12-20 | 1992-07-09 | Baxter International Inc. | Systems and methods eradicating contaminants in fluids |
| US6274100B1 (en) * | 1998-11-05 | 2001-08-14 | J.L. Shepherd & Associated | Process irradiator |
Non-Patent Citations (4)
| Title |
|---|
| JP特开2000-262595A 2000.09.26 |
| JP特开2002-136577A 2002.05.14 |
| 黎儒青 等.采用137Csγ射线辐照灭活红细胞血液制品中大肠杆菌的实验研究.中国输血杂志20 1.2007,20(1),21-23. |
| 黎儒青 等.采用137Csγ射线辐照灭活红细胞血液制品中大肠杆菌的实验研究.中国输血杂志20 1.2007,20(1),21-23. * |
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| Publication number | Publication date |
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| CN1973919A (en) | 2007-06-06 |
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Granted publication date: 20100609 Termination date: 20171214 |