CN104304595A - Semen cuscutae health tea capable of removing liver-fire for improving eyesight and preparation method thereof - Google Patents

Semen cuscutae health tea capable of removing liver-fire for improving eyesight and preparation method thereof Download PDF

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CN104304595A
CN104304595A CN201410635818.0A CN201410635818A CN104304595A CN 104304595 A CN104304595 A CN 104304595A CN 201410635818 A CN201410635818 A CN 201410635818A CN 104304595 A CN104304595 A CN 104304595A
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liver
chinese dodder
preparation
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不公告发明人
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Qingdao Hengbo Instrument Co Ltd
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Qingdao Hengbo Instrument Co Ltd
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Abstract

The invention discloses a semen cuscutae health tea capable of removing liver-fire for improving eyesight. The semen cuscutae health tea is prepared from the following raw material medicines in parts by weight: 10 to 50 parts of semen cuscutae, 10 to 20 parts of boxthorn leaves, 10 to 20 parts of radix ophiopogonis, 10 to 20 parts of glossy privet fruits, 10 to 20 parts of pipewort, 10 to 20 parts of radix paeoniae alba, 10 to 20 parts of semen cassiae, 10 to 20 parts of radix salviae miltiorrhizae, 10 to 20 parts of semen plantaginis, 10 to 20 parts of poria cocos, 10 to 20 parts of rhizoma polygonati, 10 to 20 parts of radix polygonati officinalis, and 10 to 20 parts of schisandra chinensis. The semen cuscutae health tea aims at the general behaviors of urban office workers that do harm to the liver, such as long-time staring at a computer during work, excessive smoking and alcohol drinking, immoderate nightlife, staying up late, and frequent failure to relieve the eyes after overuse, achieves the effects of nourishing the liver and the kidney, benefiting yin, nourishing blood, tonifying deficiency, benefiting essential qi, and dispelling wind for improving eyesight, and is more pertinent; semen cuscutae nutrients are preserved to a large extent, prevented from loss during processing, and protected from secondary pollution during manufacturing. The semen cuscutae health tea is totally a health tea which is green and healthy, and is suitable for long-term use.

Description

A kind of seed of Chinese dodder health protection tea clear liver and improved vision and preparation method thereof
Technical field
The present invention relates to the health products clear liver and improved vision containing deriving from plant composition, particularly a kind of seed of Chinese dodder health protection tea clear liver and improved vision and preparation method thereof and preparation method thereof.
Background technology
The traditional Chinese medical science thinks that the liver being in charge of the eyes: " liver-QI being connected with eyes, liver and then order can distinguish the five colors ".The pathology of liver often affects and order.As deficiency of liver-blood, then two xerophtalmias, blurring of vision or yctalopia; Wind-heat of liver channel, visible hot eyes is itched bitterly; Liver-fire flaming, visible keratoconjunctivitis; Liver-yang hyperactivity, then vertigo; Liver wind agitation, looks on visible order is oblique.A wound is had in " five kinds of impairments caused by overstrain " of Huangdi's Internal Classics: " impairment of blood by looking for a long time ".Here blood, what refer to is exactly liver blood.
In fact, eyes and liver contact closely.Blood stored in the liver, namely liver has stored blood and regulates the function of blood volume, and liver opening at eye.The provisions that eyes are subject to blood just can look thing, and excessively uses eye, can make liver-blood deficiency, make binocular can not get the supply of nutrition, thus go out to lose face dry and astringent, see thing is fuzzy, yctalopia etc.In addition, long-term sitting eye, except binocular blood supply insufficiency, cervical vertebra, lumbar vertebrae also can produce strain, less than alleviation, also can must cause damage to liver.In this case, occur that eyes are tired, visual impairment, even sallow complexion, dizzy symptom, just not strange yet.
Modern metropolitan cities working clan generally uses computer office, and tobacco and wine are immoderate, and night life is uncontrolled, stays up late, and these have all directly injured irritability.Look for a long time and radiation, the eye health for computer gang has buried hidden danger.This kind of people needs to protect liver while attention eye hygiene and nourishes blood.
" seed of Chinese dodder ", has another name called that SEMEN CUSCUTAE, Tu silk are real, sub without ma rattan, dodder laurel, Tu rattan, Tu thread, wild fox silk, beans parasitism, herba fibraureae recisae, trailing plants silk etc., is the seed of convolvulus cuscuta plant.There is the merit of " continuous wound absolutely, tonifying for the deficiency, the strong people of benefit ".The effect that " Mingyi Bielu " calls it to be had " supporting flesh reinforcing yin essence, hard muscles and bones ".Motherland's medical science is thought, seed of Chinese dodder acrid-sweet flavor, and property is put down, and enters liver, kidney two warp.There is tonifying kidney and benefiting sperm, nourish the liver to improve visual acuity, antiabortive effect.Can be used for soreness of waist and knee joint, impotence, premature ejaculation, seminal emission, the enuresis, the frequent micturition heeltap, tinnitus, a dizzy dim eyesight, hypopsia, threatened abortion, the inferior disease of band.。
" book on Chinese herbal medicine converges and says ": " warm spleen helps the medicine of stomach also for the seed of Chinese dodder, kidney tonifying nourishing the liver.But to mend and not high, temperature and not dry, therefore enter kidney channel, void can be mended, in fact can be in order to, cold can temperature, heat can be cool, wet can be dry, dryly can to moisten.If non-golden cypress, the wind-weed, bitter cold and not warm, has the gas rushing down kidney channel; If non-Chinese cassia tree, intelligence development, hot and not cool, there is the dry of kidney channel; If non-desert cistanche, trivial sun, sweet one-tenth and stagnant gas, have the wet person of raw kidney channel than also.As " legendary god of farming's book on Chinese herbal medicine " is called continuous wound absolutely, beneficial strength, improving eyesight essence, all by kidney tonifying nourishing the liver, levying of taste of temperature reason is tested also.″
" book on Chinese herbal medicine is newly organized ": " seed of Chinese dodder, can reuse, also can be special simply.The people that chance is had a guilty conscience, day and night dream, the essence frequently person of letting out, with the seed of Chinese dodder three liang, ten bowls, water, liquor three bowls, point three clothes, early, the noon, evening each clothes namely stop.And never lose again.This be the heart, liver, kidney three through neat disease, caused by extreme misery two void.The panacea of the positive bushing of the seed of Chinese dodder, liver, kidney, the other taste that condition is not assorted again, then power is especially special, so directly can enter three warps to receive effect also.He is as uneasy in night dream, and two blurred visions are dark, and biped is weak, one of all can to use, two liang, same to ginseng, cultivated land, the bighead atractylodes rhizome, mountain sprout and so on, with more than make outstanding contributions.″
" herbal classic is met former ": " liver kidney qi is divided also for the seed of Chinese dodder, dispelling pathogenic wind for improving eyesight.Its property and flavor of peppery and warm matter is glued, and warms up waist knee be as good as with the strong muscle of the bark of eucommia.Its merit specially in beneficial marrow, hard muscles and bones, only something lost is let out, and stem essence of trembling with fear goes out, and drown and have the heeltap, go knee shin aching and limp, old man liver kidney qi deficiency, pain in the back knee is cold, close Psoralea corylifolia, the bark of eucommia with it, all manadesmas all belong to liver also.Deficiency of vital energy pupil, without refreshing person, helps it with the tuber of dwarf lilyturf, and honeyed bolus takes, effect.All penis ultroerection not impotence, dry feces, the red puckery person of little water not use, partially also supporing yang with its property.″
" book on Chinese herbal medicine justice ": " Tu silk is that yin-nourishing dredging collateral is top grade.Its taste is micro-pungent, then have sun in the moon, keep and can walk, different absolutely with the relatively greasy stagnant person of all medicines of other enriching yin.Among Miao's secondary alcohol meaning five tastes, Xin Tongsi gas, " warp " Yan Xin is to moisten it, and the genus of the seed of Chinese dodder is also, and with scorching pungent of pungent perfume (or spice), widely different difference, institute's solution is very true and pertinent." herbal classic " continuous wound absolutely, tonifying for the deficiency, beneficial strength, fertile strong people, among nourishing, all has logical hundred arteries and veins of a surname, Wen Yunyang and meaning.Juice removes face Shao-, also the function of soft and moist skin.Clothes of a specified duration then cloudy liquid foot and order is self-evident." not Lu " strong flesh of so-called yin-nourishing, hard muscles and bones, the also justice of negative and positive two tune.The cold essence of stem is sliding, then Yuanyang is uncomfortable and Zhiyin is not taken the photograph yet, and drowning has the heeltap, then cloth and air erectile problem be not for kidney yang.Yearningly dry with regard to bitter taste, bright is the drying up of cloudy liquid, and cold blood becomes long-pending, not declaring also for yang-energy, only this kind enriching yin liquid and compress sun and, circulate hundred arteries and veins, so control it.To look the special in tonifying yin of glutinous rehmannia generation, keep and do not walk person, intrinsic.″
Various nourishing the liver liver-protection health-care product, medicine spread unchecked on the market now, but great majority are had a good apperance only, false propaganda on a grand scale, probably without any health care, but cause the huge injury of the person, therefore, the health products of the effective liver protecting of search of health have very real significance.Chinese medicine liver protecting has advantage that is nontoxic, that can be absorbed completely by organism, is the Main way that we study.Modern metropolitan cities working clan generally uses computer office to look for a long time, tobacco and wine are immoderate, the behavior of the injury livers such as night life is uncontrolled, stay up late, the provisions that eyes are subject to blood just can look thing, and excessively use eye, can liver-blood deficiency be made, make binocular can not get the supply of nutrition, thus go out to lose face dry and astringent, see thing is fuzzy, yctalopia etc.In addition, long-term sitting eye, except binocular blood supply insufficiency, cervical vertebra, lumbar vertebrae also can produce strain, less than alleviation, also can must cause damage to liver.If probably be difficult to adhere to by drug therapy simple, carelessly use eyedrops more can make eyes damaged, cause various illness in eye or blind danger, and it is cumbersome to take Chinese medicine, mouthfeel is not good, unsuitable long-term taking, and effect is also not necessarily desirable.
Summary of the invention
Technical problem to be solved by this invention is, for modern metropolitan cities, working clan generally uses computer office, look for a long time, tobacco and wine are immoderate, the behavior of the injury livers such as night life is uncontrolled, stay up late, the provisions that eyes are subject to blood just can look thing, and excessively uses eye, can make liver-blood deficiency, make binocular can not get the supply of nutrition, thus go out to lose face dry and astringent, see thing is fuzzy, yctalopia etc.In addition, long-term sitting eye, except binocular blood supply insufficiency, cervical vertebra, lumbar vertebrae also can produce strain, less than alleviation, also can must cause damage to liver.If probably be difficult to adhere to by drug therapy simple, carelessly use eyedrops more can make eyes damaged, cause various illness in eye or blind danger, and it is cumbersome to take Chinese medicine, mouthfeel is not good, unsuitable long-term taking, and effect is also not necessarily desirable.
For solving the problems of the technologies described above, the invention provides a kind of seed of Chinese dodder health protection tea clear liver and improved vision, in seed of Chinese dodder health protection tea described in it, the parts by weight of various bulk drug can be: the seed of Chinese dodder 10 ~ 50 parts, folium lycii 10 ~ 20 parts, the tuber of dwarf lilyturf 10 ~ 20 parts, the fruit of glossy privet 10 ~ 20 parts, pipewort 10 ~ 20 parts, the root of herbaceous peony 10 ~ 20 parts, cassia seed 10 ~ 20 parts, the red sage root 10 ~ 20 parts, plantain seed 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, sealwort 10 ~ 20 parts, radix polygonati officinalis 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine.
The described seed of Chinese dodder health protection tea clear liver and improved vision, in seed of Chinese dodder health protection tea described in it, the parts by weight of various bulk drug can also be: the seed of Chinese dodder 10 ~ 30 parts, folium lycii 10 ~ 15 parts, the tuber of dwarf lilyturf 10 ~ 15 parts, the fruit of glossy privet 10 ~ 15 parts, pipewort 10 ~ 15 parts, the root of herbaceous peony 10 ~ 15 parts, cassia seed 10 ~ 20 parts, the red sage root 10 ~ 20 parts, plantain seed 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, sealwort 10 ~ 20 parts, radix polygonati officinalis 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine.
The described seed of Chinese dodder health protection tea clear liver and improved vision, in seed of Chinese dodder health protection tea described in it, the parts by weight of various bulk drug also can be: the seed of Chinese dodder 10 ~ 40 parts, folium lycii 10 ~ 20 parts, the tuber of dwarf lilyturf 10 ~ 20 parts, the fruit of glossy privet 10 ~ 20 parts, pipewort 10 ~ 20 parts, the root of herbaceous peony 10 ~ 20 parts, cassia seed 10 ~ 15 parts, the red sage root 10 ~ 15 parts, plantain seed 10 ~ 15 parts, 10 ~ 15 parts, Poria cocos, sealwort 10 ~ 15 parts, radix polygonati officinalis 10 ~ 15 parts, 10 ~ 15 parts, the fruit of Chinese magnoliavine.
For solving the problems of the technologies described above, the present invention also provides the preparation method of a kind of seed of Chinese dodder health protection tea clear liver and improved vision, and its preparation method comprises the following steps:
A. the preparation of the seed of Chinese dodder;
B. the preparation of folium lycii;
C. the preparation of other raw materials;
D. the seed of Chinese dodder folium lycii prepared and other raw materials are mixed, disinfection by ultraviolet light is packed.
In described step a, ripe seed of Chinese dodder fruit of can gathering in 9 ~ October, together cuts off with host, dries, lay seed, decontamination of winnowing with a dustpan, and cleans, dries; The seed of Chinese dodder of drying is put into 80-100 DEG C baking machine turning in fry 30-45 minute shaping, take out after naturally dries.
In described step b, the fresh folium lycii collected can be cleaned, the airing time, at 7-12 hour, parches; The folium lycii that airing is good is put into the pot that completes and remove the blue or green 30-40 minute that completes at 80-120 DEG C, folium lycii taking-up after completing is dried in the shade afterwards naturally, put into large iron pan to knead, knead on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, the baking machine turning in putting into 80-100 DEG C when becoming dark brown fry 30-45 minute shaping, naturally dries after taking out.
In described step c, other raw materials can be put into large iron pan and stir-fry, when color start blackout, start little fire stir-fry 20-30 minute shaping; Naturally dry after taking out.
In described steps d, the seed of Chinese dodder prepared and other raw materials can be mixed, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 70-100 DEG C, and disinfection by ultraviolet light is packed, and naturally dries after taking out.
For solving the problems of the technologies described above, the present invention reoffers the preparation method of a kind of seed of Chinese dodder health protection tea clear liver and improved vision, and the preparation method of described seed of Chinese dodder health protection tea can also comprise the following steps:
A. the preparation of the seed of Chinese dodder;
B. particle made by other raw materials;
C. the seed of Chinese dodder prepared is mixed with other feed particles things, disinfection by ultraviolet light, dress bag.
In described step b, all the other raw materials described can be steeped in 10 times amount ethanol and soak more than 24 hours, No. 2 extracts each 1 ~ 2 hour, are merged and leave standstill by then heating and refluxing extraction 2 times, remove supernatant, merge extract, leave standstill 24 hours, remove supernatant, when to put into thickener reduced pressure concentration relative density be 80 DEG C 1.36 medicinal extract, stand for standby use; Then medicinal extract is added honey to be in harmonious proportion, put into granulator and granulate dry.
The present invention is nourishing liver and kidney, beneficial the moon nourishes blood, qi-restoratives benefit vital essence, dispelling pathogenic wind for improving eyesight, nourishing liver and kidney effect, and specific aim is more originally strong; Computer office is generally used to look for a long time for city working clan, tobacco and wine are immoderate, night life is uncontrolled, the behavior of liver of staying up late, excessively must injure less than alleviation etc. with eye, take the seed of Chinese dodder as major ingredient, add some nourishing liver and kidney, clear liver and improve vision, the Chinese medicine that mouthfeel is light, acting in conjunction, to deficiency of the yin of the liver, two xerophtalmias, hypopsia; Liver-fire flaming, red eye, swell pain; Excess eye-using is caused to eyes are dry astringently has good health-care effect.The present invention considers the making advanced technologies of Tea Processing being integrated in glossy privet fruit health-care tea, in conjunction with tea aroma raising technique.The most mouthfeel of these medicinal materials that the present invention chooses is light, and drug effect is remarkable, can long-term taking, does not also affect glossy privet fruit health-care tea taste, makes people be easy to accept.
Detailed description of the invention
The seed of Chinese dodder is listed in top grade in Shennong's Herbal.Its smell is pungent, sweet, flat nontoxic.Function with cure mainly: tonifying kidney and benefiting sperm, nourish the liver to improve visual acuity.The waist knee muscles and bones being applicable to kidney deficiency and liver is ached, legs and feet are weak and feeble, impotence and seminal emission, crazy talk, frequent urination, dripping urination, dizzy, the disease such as blurring of vision, Hiccough and deaf and women is with down, habitual abortion.Generally be listed in top grade can taking for a long time, take improving eyesight for a long time and make light of one's life by commiting suicide and prolong life.But deficiency of yang hyperactivity of fire, penis ultroerection not impotence and dry feces person prohibit clothes, according to individual physique, if there is sign of getting angry, just cut out.It can causing property hyperfunction.
" herbal classic is met former ": " liver kidney qi is divided also for the seed of Chinese dodder, dispelling pathogenic wind for improving eyesight.Its property and flavor of peppery and warm matter is glued, and warms up waist knee be as good as with the strong muscle of the bark of eucommia.Its merit specially in beneficial marrow, hard muscles and bones, only something lost is let out, and stem essence of trembling with fear goes out, and drown and have the heeltap, go knee shin aching and limp, old man liver kidney qi deficiency, pain in the back knee is cold, close Psoralea corylifolia, the bark of eucommia with it, all manadesmas all belong to liver also.Deficiency of vital energy pupil, without refreshing person, helps it with the tuber of dwarf lilyturf, and honeyed bolus takes, effect.All penis ultroerection not impotence, dry feces, the red puckery person of little water not use, partially also supporing yang with its property." generally use computer office to look for a long time for city working clan, tobacco and wine are immoderate, and uncontrolled, the excessive eye of night life must less than the behavior of injury livers such as alleviating; adopt daily drinking, and energy qi-restoratives benefit vital essence, dispelling pathogenic wind for improving eyesight; nourishing liver and kidney, plays good health-care effect.
Eyes and liver contact closely.Blood stored in the liver, namely liver has stored blood and regulates the function of blood volume, and liver opening at eye.The provisions that eyes are subject to blood just can look thing, and excessively uses eye, can make liver-blood deficiency, make binocular can not get the supply of nutrition, thus go out to lose face dry and astringent, see thing is fuzzy, yctalopia etc.In addition, long-term sitting eye, except binocular blood supply insufficiency, cervical vertebra, lumbar vertebrae also can produce strain, less than alleviation, also can must cause damage to liver.In this case, occur that eyes are tired, visual impairment, even sallow complexion, dizzy symptom, just not strange yet.Look for a long time and radiation, the eyes for computer gang are good for urine and have been buried hidden danger.
The traditional Chinese medical science thinks that the liver being in charge of the eyes: " liver-QI being connected with eyes, liver and then order can distinguish the five colors ".The pathology of liver often affects and order.As deficiency of liver-blood, then two xerophtalmias, blurring of vision or yctalopia; Wind-heat of liver channel, visible hot eyes is itched bitterly; Liver-fire flaming, visible keratoconjunctivitis; Liver-yang hyperactivity, then vertigo; Liver wind agitation, looks on visible order is oblique.
Liver controlling conveyance and dispersion, the general reference comprehensive physiological functions such as irritability has dredging, bar reaches, liter is sent out, freely let out.Ancients rush with wood gas the catharsis function resembling analogy liver reached with bar, therefore are belonged to wood in the five-element, therefore " the blue secret allusion quotation opinion of Plain Questions spirit " is said: " liver person; organ of general considers and here ", " Plain Questions six saves state of internal organs opinion " is said: " liver person; source of endurance, the residence of soul also ".The function of liver controlling conveyance and dispersion is mainly manifested in and regulates spiritual feelings will, promotes to digest and assimilate, and maintains operation three aspect of qi and blood, body fluid.
Liver opening at eye, it is foster that objective vision function mainly relies on moistening of the cloudy blood of liver; The passages through which vital energy circulates first line of a couplet order system again of liver.Therefore, whether normal the function of liver is usually reflects on order.Such as: blurred vision, yctalopia can appear in deficiency of liver-blood; Deficiency of the yin of the liver, then two xerophtalmias, hypopsia; Liver-fire flaming, then red eye, swell pain.The traditional Chinese medical science is emphasized, people wants frequent dispersing liver-energy, clearing liver poison, falls irascibility, nourishing the liver blood, and dispersing liver-energy can make the catharsis of whole body mechanism of qi unobstructed, in body on stifled then face without acne; Clearing liver poison can dissolve elimination internal pollution, and in body, nontoxic then face is without dead color; Fall irascibility and can make equilibrium between yin and yang in body, in body, not burnt then skin moisturizing is not dry; Nourishing the liver blood can nourish whole body internal organs, and liver blood is full, and then body surface gloss is flexible.Repair damaged liver, make whole body mechanism of qi free flow of qi, the smooth and easy operation of whole body qi and blood, to reach soothing the liver beauty treatment object.Toxigenic source is liver.When liver can not complete removing toxic substances work well, toxin is just stretched in vivo.First soothing the liver beauty treatment starts with from liver health, allows healthy liver complete every removing toxic substances work, thoroughly cuts off toxin source, make appearance beautiful lastingly.
The present invention is major ingredient with the seed of Chinese dodder, adds some nourishing liver and kidney, clears liver and improve vision, the Chinese medicine that mouthfeel is light, acting in conjunction, to deficiency of the yin of the liver, and two xerophtalmias, hypopsia; Liver-fire flaming, red eye, swell pain; Excess eye-using is caused to eyes are dry astringently has good health-care effect.
Folium lycii mainly containing betaine, carrotene, ascorbic acid, linoleic acid, have the amino acid of tens kinds of needed by human such as asparatate, glutamic acid, methionine, taurine, and be rich in the trace element of the multiple needed by human such as calcium Ca, iron Fe, zinc Zn, selenium Se, vitamin B1, vitamin B2, vitamin C.Lycium leaf tea has and alleviates frigidity, stomach invigorating, liver protecting and kidney invigorating, suppresses pulmonary tuberculosis, eliminates constipation, relieving insomnia, and conditioning low blood pressure, anaemia, treat various eye illness and oral inflammation, and can skin-protecting face nursing.Drink for a long time, to treat the physique cold of insufficiency type, can build up resistance especially, the effect of certain improvement physique can be played.Folium lycii has many effects, and aobvious author has three: heat-clearing, reduces blood pressure, and logical intestines profit just.
Root of herbaceous peony nourishing blood and liver, pain relieving in slow, astringe yin receives sweat.Control chest abdomen pain over the hypochondriac region, rush down dysentery stomachache, spontaneous sweating, fever due to yin deficiency, irregular menstruation, uterine bleeding, under band." Japan hanako materia medica ": " control wind and mend consumptive disease, all diseases of main woman, and antenatal rear all diseases, Tong Yueshui, relieving restlessness of bringing down a fever, beneficial gas, control the capable hot disease in sky, pest miasma is shied mad, and married woman's blood is transported, and intestines diarrhea due to wind-evil blood, hemorrhoid complicated by anal fistula carbuncle on the back, sore scabies, headache, improving eyesight, hot eyes, the triangular mass of mucous membrane growing from the inner corner of the eye." radix paeoniae alba extraction raises hepatic injury caused by D-galactosamine and SGPT obvious antagonism, SGPT can be made to reduce, and make hepatocellular pathology and downright bad recover normal. the gross activity of the lactic dehydrogenase that the acute liver injury of rats that the ethanol extract of the root of herbaceous peony can make aflatoxin B1 cause shows and isoenzymes raises and is minimized. and white peony root's total glycoside can suppress carbon tetrachloride induced mice Plasma glutamate-pyruvate transaminase and lactic dehydrogenase to raise, and acid denaturation is bitten to liver organization, necrosis has certain antagonism. and someone thinks, hepatic injury caused by carbon tetrachloride destroys because of membrane structure generation peroxidation, glutamic-pyruvic transaminase and lactic dehydrogenase in blood are raised, white peony root's total glycoside may have protective effect to hepatocellular injury, therefore transaminase can be made to reduce.
Cassia seed bitter, sweet, one-tenth, cold nature, enters liver, kidney, large intestine channel; Relax bowel, lipopenicillinase improving eyesight, treatment constipation and high fat of blood, hypertension.Clear liver and improve vision, sharp water defaecation, has laxative action, reducing blood pressure and blood fat.Cassia seed can be arranged in pairs or groups with other Herb Teas, has good greasy effect of toxin expelling oil extraction.Can effect be reached: the flat liver of heat-clearing, blood fat-reducing blood pressure-decreasing, relax bowel, improving eyesight benefit eyeball.Modern " TV race ", " cybraian " etc. easily cause the crowd of eye fatigue often to drink, but night preferably drinks less.
Sealwort: sealwort is used as medicine with rhizome.There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney benefiting functions.Be used for the treatment of weakness of the spleen and the stomach, fatigue and asthenia, dry food is few, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, and interior heat such as to be quenched one's thirst the disease.Very effective in cure for diabetes.Sealwort has hypotensive, hypoglycemic, reducing blood lipid, atherosclerosis, and delay senility and effect such as antibacterial grade, Siberian solomonseal rhizome polysaccharide has Immunestimulatory effect.For the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, and the labor of lung-kidney deficiency is coughed chronic cough etc.For weakness of the spleen and the stomach.Both tonifying spleen-yin, again beneficial temper, obtain dizzy, soreness and weakness of waist and knees for deficiency of kidney essence, poliosis and quenching one's thirst.Sealwort strengthens the bone, beneficial marrow, bleaches and sends out; The cough phlegm be suitable for caused by lack of lung-YIN is few, dry cough without phlegm, the diseases such as hemoptysis.
The order that the fruit of glossy privet is used for the deficiency of liver-yin and kidney-yin is secretly failed to understand, hypopsia, poliosis, soreness of waist tinnitus and fever due to yin deficiency etc.This product energy tonifying liver kidney yin, but the efficacy of a drug is gentle, slowly must get effect.Control order secretly to fail to understand, often join cultivated land, matrimony vine is equal to use, controls poliosis, and often join the same use of mulberries, fever due to yin deficiency, often joins the root bark of Chinese wolf-berry.The deficiency of liver-yin and kidney-yin, Light-headedness, seminal emission tinnitus, soreness and weakness of waist and knees, poliosis, coronary heart disease, hyperlipidemia, hypertension, chronic hepatitis.The protective effect research of liver is thought, the fruit of glossy privet contains oleanolic acid, to rat skin lower injection, serum glutamic pyruvic transminase can be reduced, there is obvious protective effect to the hepatic injury of Carbon Tetrachloride Induced, and can liver cell regeneration be promoted. oleanolic acid also can make triglycerides accumulation minimizing in liver, degeneration of liver cells necrosis obviously alleviates, glycogen accumulation increases, serum γglobulin declines; Ultra microstructure visible liver cell mitochondrial swelling and endosomal vesicle sex change alleviate, hepatic tissue interstitial inflammation habituation.
The red sage root is bitter, is slightly cold.The thoughts of returning home, Liver Channel.Stasis-dispelling and pain-killing, activating blood to promote menstruation, clear away heart-fire relieving restlessness.For irregular menstruation, through closing dysmenorrhoea, a lump in the abdomen causing distension and pain, and chest ventral spine pain, hot numbness pain, sore swells and ache, dysphoria and insomnia.For sternal rib hypochondriac pain, arthralgia due to wind-dampness, abdominal mass lumps, and sore swells and ache, fall fall forward grieved, irregular menstruation, through closing dysmenorrhoea, postpartum stasis of blood pain etc.Treatment sternal rib pain, abdominal mass caking, and irregular menstruation, through amenorrhoea pain, there is good effect." detailed outline " carries: the red sage root, and by " the sensible opinion of married woman " cloud, gynecopathy controlled by Siwu Tang, pays no attention to antenatal postpartum, how many through water, all can be general, and the only taste red sage root falls apart, and cures mainly identical with it.The lid red sage root can break place blood, mends new blood, peaceful tire, and fall stillborn foetus, only metrorrhagia stagnant under, menstruation regulating arteries and veins.Main Compositions of Radix Salviae Miltiorrhizae tanshinone has hemangiectasis, improves circulation, removes the effects such as intravascular coagulation, has effect of invigorating blood circulation trace, and can promote that liver blood circulates, be beneficial to liver cell regeneration.
Pipewort Classification system: Eriocaulon buergerianum is pungent sweet, cool; Wind and heat eliminating, removing nebula.Cure mainly and control order screen, sparrow is blind, headache, dentalgia, larynx numbness, nosebleed epistaxis.Wind-heat red eye, swell pain, photophobia, screen of looking unfamiliar film.The frivolous liter of this product falls apart, and kind evacuates women's head-ornaments wind-heat, removing nebula, attacks caused red eye, swell pain, the many tear of photophobia, screen of looking unfamiliar film person with controlling in wind-heat, can with the compatibility such as schizonepeta, cassia seed, felwort, as pipewort soup." Kaibao Bencao ": " main treatment larynx numbness, tooth wind pain and all sore scabies." Compendium of Material Medica: " the light property of pipewort body is floated, can the bright dividing line of up sun.Allly control all diseases in order, to add and with it, very good.The merit of removing nebula, like on chrysanthemum also.”
Plantain seed nature and flavor: sweet; Light; Cold nature.Gui Jing: return lung channel; Liver Channel; Kidney channel; Urinary bladder channel.Function: reducing fever and causing diuresis; Excreting dampness antidiarrheal; Improving eyesight; Eliminate the phlegm.Cure mainly: main difficult urination; Under stranguria with turbid discharge band; Oedema turgor; Summer-heat and damp rushes down dysentery; Hot eyes is hidden from view; Phlegm heat is coughed and is breathed heavily." property of medicine is fallen ": can remove wind poison, hepatic stroke heat, malicious wind dotting punch order, red pain is hidden from view, cerebralgia lacrimation, goes ambition dysphoria with smothery sensation." Japan hanako materia medica ": diuresis drenches puckery, establishing-Yang.Control de-essence, vexed.Lower gas." medicine origin ": main urinary obstruction; Lead little pathogenic heat in the bowels.
Poria cocos taste is sweet, light, property is put down, and is used as medicine and has the function of clearing damp and promoting diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.Modern medicine study: Poria cocos energy enhanced machine body immunity function, pachymaran has significantly antitumor and protect the liver dirty effect.Poria cocos slightly sweet flavor is put down, and enters the heart, lung, the spleen channel.There is eliminating dampness and diuresis, strengthening the spleen and stomach, effect of antitoxic heart-soothing and sedative.Can control difficult urination, oedema turgor, phlegm and retained fluid is coughed inverse, vomits inverse, and vomiting during early pregnancy, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.The Li Shui of Poria cocos, is reached by strong fortune spleen PFT, different from the Chinese medicine of other direct Li Shui.For splenasthenic diarrhea, the lower Poria cocos of band can invigorating the spleen, again can excreting dampness, and for having loose bowels caused by insufficiency of the spleen dysfunction of the spleen in transportation and transformation, being with down, application Poria cocos has the effect of giving consideration to both the incidental and fundamental, the compatibilities such as normal and Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam.Can be used as tonifying lung spleen, control the adjuvant of the deficiency of vital energy.
Radix polygonati officinalis: nourishing Yin and moistening lung; Nourishing the stomach to improve the production of body fluid.Cough caused by dryness; Labor is coughed; The dry throat and mouth of pyreticosis cloudy liquid consumption wound; Interior heat is quenched one's thirst; Deficiency of Yin diseases caused by external factors; Dizzy dizzy; Muscle arteries and veins contraction pain.The sweet greasiness of radix polygonati officinalis taste, matter is soft and moisten, and is the good medicine of nourishing Yin and promoting production of body fluid simply.Vitamin A contained in radix polygonati officinalis, improves dry and cracked, rough skin situation, makes it soft lubrication.Play the effect of beauty and skin care." stem is tetanic, like bamboo arrow shaft, has joint for Collective Notes to the Canon of Materia medica cloud." therefore have the name of radix polygonati officinalis.The rhizome of plant can hyoscine, and Chinese medicine name is also radix polygonati officinalis, and autumn excavates, and cleans, shines to softness, repeatedly rub, and airing, to without hard-core, is dried, or steams thoroughly, rubs to translucent, dries, and cuts sheet or section use." book on Chinese herbal medicine justice ": " control lung stomach scorching, body fluid dries up, and thirsty choke is dry waits disease, and exuberance of stomach fire, the dry paddy that yearningly disappears, polyorexia person, You Youjie is imitated ".
The fruit of Chinese magnoliavine: the fruit of Chinese magnoliavine is used as medicine with rhizome.There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney benefiting functions.Be used for the treatment of weakness of the spleen and the stomach, fatigue and asthenia, dry food is few, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, and interior heat such as to be quenched one's thirst the disease.Very effective in cure for diabetes.The fruit of Chinese magnoliavine has hypotensive, hypoglycemic, reducing blood lipid, atherosclerosis, and delay senility and effect such as antibacterial grade, Fructus Schisandrae Polysaccharide has Immunestimulatory effect.For the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, and the labor of lung-kidney deficiency is coughed chronic cough etc.For weakness of the spleen and the stomach.Both tonifying spleen-yin, again beneficial temper, obtain dizzy, soreness and weakness of waist and knees for deficiency of kidney essence, poliosis and quenching one's thirst.The fruit of Chinese magnoliavine is strengthened the bone, and strong marrow, bleaches and send out; The cough phlegm be suitable for caused by lack of lung-YIN is few, dry cough without phlegm, the diseases such as hemoptysis.
The tuber of dwarf lilyturf nature,taste and action: sweet, micro-hardship, cool, Yin-nourishing and body fluid promoting, moisten the lung and relieve the cough, clear away heart-fire relieving restlessness.Cure mainly consumption of body fluid caused by febrile disease, vexed, thirsty, dry throat lung heat, cough, pulmonary tuberculosis.Join the root of straight ladybell, lung stomach is ruled together, and has the cool stomach of clearing lung-heat, the good effectiveness of nourishing Yin and promoting production of body fluid, for the few phlegm of the dry cough caused by the lung-dryness syndrome due to yin deficiency or thermal burn lung yin, and the diseases such as dry throat.Join the fruit of Chinese magnoliavine, sour-sweet herbs nourishing yin, keep the moon so stay sun, sun stays sweat from stopping.Function yin-nourishing arrest sweating, with controlling, deficiency of Yin sweat is many, palpitaition, chronic cough of deficiency lung, and few phlegm or phlegm glue not well etc.
Specific embodiment 1:
The preparation of the seed of Chinese dodder: ripe seed of Chinese dodder fruit of gathering in 9 ~ October, together cuts off with host, dries, lay seed, decontamination of winnowing with a dustpan, and cleans, dries; The seed of Chinese dodder of drying is put into 80-100 DEG C baking machine turning in fry 30-45 minute shaping, take out after naturally dries.
Prepared by folium lycii: cleaned by the folium lycii of collection, the airing time, at 7-12 hour, parches; The folium lycii that airing is good is put into the pot that completes and remove the blue or green 30-40 minute that completes at 80-120 DEG C, folium lycii taking-up after completing is dried in the shade afterwards naturally, put into large iron pan to knead, knead on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, the baking machine turning in putting into 80-100 DEG C when becoming dark brown fry 30-45 minute shaping, naturally dries after taking out.
The preparation of other raw materials: other raw materials are put into large iron pan and stir-fried, when color start blackout, start little fire stir-fry 20-30 minute shaping; Naturally dry after taking out.
Mixing: the seed of Chinese dodder prepared and other raw materials are mixed, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 70-100 DEG C, and disinfection by ultraviolet light is packed, and naturally dries after taking out.
Specific embodiment 2:
The preparation of the seed of Chinese dodder: ripe seed of Chinese dodder fruit of gathering in 9 ~ October, together cuts off with host, dries, lay seed, decontamination of winnowing with a dustpan, and cleans, dries; The seed of Chinese dodder of drying is put into 80-100 DEG C baking machine turning in fry 30-45 minute shaping, take out after naturally dries, about 5000g.
Prepared by folium lycii: cleaned by the folium lycii 1500g of collection, the airing time, at 7-12 hour, parches; The folium lycii that airing is good is put into the pot that completes and remove the blue or green 30-40 minute that completes at 80-120 DEG C, folium lycii taking-up after completing is dried in the shade afterwards naturally, put into large iron pan to knead, knead on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, the baking machine turning in putting into 80-100 DEG C when becoming dark brown fry 30-45 minute shaping, naturally dries after taking out.
Prepared by all the other raw materials: by all the other raw materials 1500g tuber of dwarf lilyturf, fruit of glossy privet 1500g, pipewort 1500g, root of herbaceous peony 1500g, cassia seed 1500g, red sage root 1500g, plantain seed 1500g, Poria cocos 1500g, sealwort 1500g, radix polygonati officinalis 1500g, fruit of Chinese magnoliavine 1500g, put into large iron pan to stir-fry, when color start blackout, start little fire stir-fry 20-30 minute shaping; Naturally dry after taking out.
Packaging: the seed of Chinese dodder prepared and the mixing of other raw materials, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 70-100 DEG C, and disinfection by ultraviolet light is packed, and naturally dries after taking out.Then can pack product, the little tea bag of 10-15 gram can be distributed into, also entirety can be mixed into bag sale.
Specific embodiment 3:
Pluck 1000g folium lycii, folium lycii is put into clear water washing, wash away floating ash dirty, do not rub energetically, be put on bamboo mat by washed folium lycii and ted, note ventilating, upset, makes it naturally parch.Complete in electric pot, complete 30-40 minute at 70-100 DEG C; Naturally, dry after being taken out by folium lycii after completing, knead with hand, or put into large iron pan and carry out, on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, baking machine turning in stir-fry 30-45 minute of putting into 80-100 DEG C when becoming dark brown is shaping.Cleaned by the seed of Chinese dodder 3500g of results, removing stalk, leaf and impurity, dry, then soak one with 70 degree of white wine, steams and thoroughly dry, for subsequent use again; Again by other raw materials 1200g tuber of dwarf lilyturf, fruit of glossy privet 1100g, pipewort 1200g, root of herbaceous peony 1100g, cassia seed 1100g, red sage root 1100g, plantain seed 1100g, Poria cocos 1200g, sealwort 1100g, radix polygonati officinalis 1200g, fruit of Chinese magnoliavine 1100g, clean, the airing time, at 7-12 hour, parches; The raw material that airing is good is put into the pot that completes and remove the blue or green 30-40 minute that completes at 80-120 DEG C, raw material taking-up after completing is dried in the shade afterwards naturally, put into large iron pan to knead, knead on first backward downwards, firmly want evenly, put into 80-100 DEG C baking machine turning in fry 30-45 minute shaping, take out after naturally dries.The seed of Chinese dodder prepared and the mixing of other raw materials, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 70-100 DEG C, and disinfection by ultraviolet light is packed, and naturally dries after taking out.Then can pack product, the little tea bag of 10-15 gram can be distributed into, also entirety can be mixed into bag sale.
Specific embodiment 4:
The seed of Chinese dodder 4000g of results is cleaned, removing stalk, leaf and impurity, dry the baking machine turning in seed of Chinese dodder of drying being put into 80-100 DEG C fry 30-45 minute shaping, naturally dries after taking out, for subsequent use; By all the other raw material folium lyciis 1200g, the tuber of dwarf lilyturf 1200g, fruit of glossy privet 1200g, pipewort 1100g, root of herbaceous peony 1100g, cassia seed 1100g, red sage root 1100g, plantain seed 1100g, Poria cocos 1200g, sealwort 1200g, radix polygonati officinalis 1100g, fruit of Chinese magnoliavine 1100g, steeps in 10 times amount ethanol and soaks more than 24 hours, then heating and refluxing extraction 2 times, each 1 ~ 2 hour, No. 2 extracts are merged and leaves standstill, remove supernatant, merge extract, leave standstill 24 hours, remove supernatant, when to put into thickener reduced pressure concentration relative density be 80 DEG C 1.36 medicinal extract, stand for standby use; Then medicinal extract is added honey to be in harmonious proportion, put into granulator and granulate dry, the seed of Chinese dodder of naturally drying after taking-up and the mixing of other raw materials, disinfection by ultraviolet light is packed, and can be distributed into the little tea bag of 10-15 gram, also entirety can be mixed into bag sale.
Pharmacological toxicity is tested
Acute toxicity testing
One, test material:
Animal: Kunming mouse, body weight 21-24g, male and female half and half, Shandong University's biology laboratory breeding.Experiment thing: decoction liquor of the present invention.
Two, method:
1, LD50 calculates: adopt improvement karber's method, mouse is divided into 5 groups at random, often organize 10, male and female half and half, dissolve adding distil water of the present invention, are made into Cmax, by the administration of mouse maximum permission capacity, institute is followed successively by 18,14.4 to dosage by crude drug amount, 11.5,9.2,7.4 (g.kg-1), in animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml, observes animal dead situation.
2, maximum tolerated dose measures (MTD value): get mouse 20, each 10 of male and female.Adding distil water of the present invention is dissolved, is made into maximum concentration, by the maximal tolerance dose of animal, feed device and can twitch to inject to fill with and be as the criterion.In animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml (every ml containing crude drug 0.36g), total dose is 18g crude drug/kg.d, 300 times of quite clinical adult 50Kg body weight consumption.Continuous Observation 7 days after administration.
Three, result of the test:
In LD50 calculates when giving mouse with maximum acceptable concentration and maximum permission capacity (18g/Kg.d), have no dead mouse, namely LD50 is not measured, ask maximum tolerated dose only, in 7 day observation period, its appetite of animal, activity, hair color, the state of mind etc. are all normal, grow normal, there are no death.Namely select the 300 times of doses being equivalent to clinical dosage, and have no adverse reaction, show that acute toxicity is minimum, MTD > 18g/Kg.d.
Experimental example 2: long term toxicity test data
Decoction agent of the present invention is through the gastric infusion long-term toxicity test for animals result of 6 months: SD rat is divided into three groups, often organizes 30, male and female half and half (be divided into high, medium and low three dosage groups, often organize 10), wherein first group through gavage to physiological saline; Be 0.25g, 2.5g and 12.5g/kg.d to dosage of the present invention through gavage for second group; 3rd group is 0.5mg, 5.0mg and 50.0mg/kg.d through gavage to the dosage of Lovastatin.During administration, observe the evaluation that the indexs such as the clinical manifestation after each treated animal administration, hematology, blood biochemistry, organ coefficient and histopathology carry out drug toxicity respectively.Result of study: the present Lovastatin 50mg/kg.d of major toxicity reaction table and 5.0mg group, shows SD rat upon administration and has occurred reaction and the symptoms such as salivation, hair are fluffy, busy, diarrhoea, step, total food ration and losing weight; Blood test display total white blood cells increases to some extent, and Erythrocytes, content of hemoglobin and platelet count obviously decline (the equal < 0.05 of P); Blood biochemistry checking display ALT, AST, ALP and CK raise 1 ~ 8 times (the equal < 0.05 of P), and creatinine and urea nitrogen raise to some extent (the equal < 0.05 of P), but do not cause animal dead; Histopathological analysis result display Lovastatin 50mg/kg.d group has occurred that the liver-kidney diseases reason similar to people changes.And all there is not similar reaction in physiological saline group and 0.25g, 2.5g and 12.5g/kg.d of the present invention tri-dosage groups and Lovastatin 0.5mg/kg.d dosage group during whole administration, at convalescence viewing duration, occur that the symptom of each treated animal of reaction fades away recovery normal condition.Visible the present invention not only can reduce the toxic and side effect of Lovastatin, and the clinical non-toxic of Lovastatin can be made to be increased to 5 ~ 25 times (the equal < 0.01 of P).
Test example 3: cumulative toxicity is tested:
The present invention decocts agent to mouse by 7.69,19.18 and 43.21g crude drug/kg continuous use 15 weeks (1.0ml/100g body weight, every day 2 times) and drug withdrawal after 3 weeks, result shows: the index such as hair, behavior, stool and urine, body weight, organ weights, blood picture, hepatic and renal function, blood sugar, blood fat of Chinese medicine preparation of the present invention to rat all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 3 weeks, and each internal organs of rat are all without obviously changing.Illustrate that Chinese medicine preparation oral capsule of the present invention is little to toxicity after rat long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Pharmacological experiment illustrates:
1 experiment material
1.1 medicine
The fruit of glossy privet tea (preparing by the method for embodiment 2) that the present invention is clear liver and improved vision; Positive control drug: Qiju Dihuang Wan, Tongrentang produces, commercially available.
1.2 animal Wistar rats, Kunming mouse, ♀ ♂ all uses.
2 impacts on ALT, ET, NO content in hepatic injury mice serum
2.1 groupings: get 90 kunming mices and be divided into 6 groups at random, often organize 15, A group is Normal group; B group is model control group; C group is positive controls; D1 group is low dose group of the present invention, and D2 group is dosage group in the present invention, and D3 group is high dose group of the present invention;
2.2 modeling methods: the method establishment immunological liver injury in mice model adopting BCG vaccine and lipopolysaccharides associating.After each treated animal adaptability feeds 3d, except Normal group, every mouse 1 tail vein injection BCG vaccine 5 × 107 viable bacterias, 12d intravenous injection lipopolysaccharides 7.5 μ g/ mouse after injection of BCG, put to death after 16h and draw materials, Normal group injects normal saline 2 times all in the same way.
2.3 administrations and process: the first day of intravenous injection BCG vaccine plays beginning gastric infusion, 1 time/d.Normal group and model control group: physiological saline gavage, gavage amount is with the medication capacity of medication therapy groups; Positive control medicine treatment group: Qiju Dihuang Wan, 5.9g/kg dosed administration; Of the present invention group of low 3.9g/kg, middle 7.8g/kg, high 11.7g/kg dosed administration.Normal group is 16h after 12d injecting normal saline, and eyeball rear vein beard gets blood, and puts to death animal and get hepatic tissue censorship; All the other groups are 16h after intravenous injection lipopolysaccharides, and eyeball rear vein beard gets blood, and puts to death animal and get hepatic tissue censorship.
2.4 observation index and detection method: 1. detect glutamate pyruvate transaminase (ALT): adopt chemical colorimetry to measure.2. endogenous nitric oxide (NO) measures: adopt radioimmunology, take 0.5g liver and make 10% liver tissue homogenate, under 4 DEG C of conditions, 3000 turns/min, centrifugal 10min, gets supernatant.3. Endothelin (ET) detects: adopt radiation to exempt from method and directly measure blood plasma ET concentration.
Serum ALT respectively organized by table 1, the situation of change of ET, NO compares
* compare with model group, * P < 0.05, * * P < 0.01; Δ compares with positive controls, Δ P < 0.05.
3, to the protective effect of chronic liver injury
Get 40 kunming mices and be divided into 4 groups at random, often organize 10, rat skin lower injection 10%5ml/kg carbon tetrachloride oil solution, 2 times weekly, injection 3 months, causes carbon tetrachloride chronic liver injury animal model continuously, observes the protective effect of medicine of the present invention to damage liver.
Normal group (A) and model control group (B): physiological saline gavage, gavage amount is with the medication capacity of medication therapy groups; Positive control medicine treatment group (C): Qiju Dihuang Wan, 2.7g/kg dosed administration; The present invention (D), 2.7g/kg dosed administration.Normal group is 16h after 12d injecting normal saline, and eyeball rear vein beard gets blood, and puts to death animal and get hepatic tissue censorship; All the other groups are 16h after intravenous injection lipopolysaccharides, and eyeball rear vein beard gets blood, and puts to death animal and get hepatic tissue censorship.
Table 2 medicine of the present invention is to the protective effect (X ± SD) of chronic liver injury rat
* compare with model group, * P < 0.05, * * P < 0.01; Δ compares with positive controls, Δ P < 0.05.
As can be seen from the above results, detecting qualified medicine of the present invention has conspicuousness to improve to ALT, ET, NO content in hepatic injury mice serum, and has obvious protective effect to chronic liver injury, and comparing with positive control medicine has significant difference.
Clinical testing:
One, experimental subjects: adopt Chinese medicine tea-drinking of the present invention altogether in 40 routine patient's experiments, wherein man 28 example, female 12 example; The oldest person 51 years old, age reckling 21 years old.Major part sufferer is white collar, readme blurred vision, yctalopia; Insomnia forgetfulness, deficiency of the yin of the liver, two xerophtalmias, hypopsia; Liver-fire flaming, red eye, swell pain; Frequent eyes are dry astringent, stay up late, dinner party of drinking; And dim complexion, female's sufferer mostly has irregular menstruation, and acne is played in face, and color spot is serious.Equal 40 people of experimental group, control group, man 22, female 18, the oldest 49 years old, minimum 21 years old.Illness is identical or similar, adopts the commercially available eyedrops that clears liver and improve vision+Chinese medicine conditioning.
Methods for the treatment of:
Usage and dosage: treatment group adopts Chinese medicine health-care tea-drinking of the present invention.Fang Yong: seed of Chinese dodder 25g, folium lycii 12g, the tuber of dwarf lilyturf 13g, fruit of glossy privet 13g, pipewort 13g, root of herbaceous peony 14g, cassia seed 14g, red sage root 14g, plantain seed 13g, Poria cocos 13g, sealwort 13g, radix polygonati officinalis 14g, fruit of Chinese magnoliavine 14g.Its usage and consumption as follows:: every day 2 bags time, brew at every turn and be limited for twice.The course for the treatment of: be limited for one month.Control group daily Chinese medicine nostrum (Qiju Dihuang Wan) adds dripping eyedrop (pearl eyesight improvement drops, commercially available), within one month, is limited.
The standard of curative effect evaluation
Cure: above symptom and sign improves completely, and patient is without any bad sensation, happy, in high spirits, and eyes are no longer dry astringent, blurred vision.Effective: sign is significantly improved, patient is substantially without bad sensation, happy, and spirit very well.Effective: sign obviously changes, random thoughts are slightly uncomfortable, but can accept, and mood is better, and energy is more abundant.Invalid: sign is without any change, and symptom, as front, feels depressed, One's spirits are drooping depressed.Dim complexion, eyes or dry astringent.
The results are shown in Table 1 liang of group comparitive study (%)
Group Number Recovery from illness Take a turn for the better Effectively Invalid Total effective rate
Treatment group 40 31(77.5) 7(17.5) 2(5) 0(0) 100
Control group 40 25(62.5) 8(30.77) 2(10) 5(12.5) 87.5
Discuss: treatment group successful of the present invention is higher than control group.Show that health tea of the present invention replaces Chinese medicine feasible.Advantage of the present invention is, drinks as daily, can improve mouthfeel, also allows people not produce and detests psychology, no longer repel Chinese medicine odor.
Computer office is generally used to look for a long time for city working clan, tobacco and wine are immoderate, uncontrolled, the excessive eye of night life must less than the behavior of injury livers such as alleviating, adopt qi-restoratives benefit vital essence, dispelling pathogenic wind for improving eyesight, nourishing liver and kidney drug matching, and it is not good to solve Chinese medicine mouthfeel, can not the shortcoming of long-term taking.
The present invention is major ingredient with the seed of Chinese dodder, adds some nourishing liver and kidney, clears liver and improve vision, the Chinese medicine that mouthfeel is light, acting in conjunction, to deficiency of the yin of the liver, and two xerophtalmias, hypopsia; Liver-fire flaming, red eye, swell pain; Excess eye-using is caused to eyes are dry astringently has good health-care effect.
The seed of Chinese dodder is listed in top grade in Shennong's Herbal.Its smell is pungent, sweet, flat nontoxic.Function with cure mainly: tonifying kidney and benefiting sperm, nourish the liver to improve visual acuity.The waist knee muscles and bones being applicable to kidney deficiency and liver is ached, legs and feet are weak and feeble, impotence and seminal emission, crazy talk, frequent urination, dripping urination, dizzy, the disease such as blurring of vision, Hiccough and deaf and women is with down, habitual abortion.Generally be listed in top grade can taking for a long time, take improving eyesight for a long time and make light of one's life by commiting suicide and prolong life.But deficiency of yang hyperactivity of fire, penis ultroerection not impotence and dry feces person prohibit clothes, according to individual physique, if there is sign of getting angry, just cut out.It can causing property hyperfunction.
" herbal classic is met former ": " liver kidney qi is divided also for the seed of Chinese dodder, dispelling pathogenic wind for improving eyesight.Its property and flavor of peppery and warm matter is glued, and warms up waist knee be as good as with the strong muscle of the bark of eucommia.Its merit specially in beneficial marrow, hard muscles and bones, only something lost is let out, and stem essence of trembling with fear goes out, and drown and have the heeltap, go knee shin aching and limp, old man liver kidney qi deficiency, pain in the back knee is cold, close Psoralea corylifolia, the bark of eucommia with it, all manadesmas all belong to liver also.Deficiency of vital energy pupil, without refreshing person, helps it with the tuber of dwarf lilyturf, and honeyed bolus takes, effect.All penis ultroerection not impotence, dry feces, the red puckery person of little water not use, partially also supporing yang with its property." generally use computer office to look for a long time for city working clan, tobacco and wine are immoderate, and uncontrolled, the excessive eye of night life must less than the behavior of injury livers such as alleviating; adopt daily drinking, and energy qi-restoratives benefit vital essence, dispelling pathogenic wind for improving eyesight; nourishing liver and kidney, plays good health-care effect.

Claims (10)

1. the seed of Chinese dodder health protection tea clear liver and improved vision, is characterized in that, in described seed of Chinese dodder health protection tea, the parts by weight of various bulk drug comprise: the seed of Chinese dodder 10 ~ 50 parts, folium lycii 10 ~ 20 parts, the tuber of dwarf lilyturf 10 ~ 20 parts, the fruit of glossy privet 10 ~ 20 parts, pipewort 10 ~ 20 parts, the root of herbaceous peony 10 ~ 20 parts, cassia seed 10 ~ 20 parts, the red sage root 10 ~ 20 parts, plantain seed 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, sealwort 10 ~ 20 parts, radix polygonati officinalis 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine.
2. the seed of Chinese dodder health protection tea clear liver and improved vision according to claim 1, is characterized in that, in described seed of Chinese dodder health protection tea, the parts by weight of various bulk drug comprise: the seed of Chinese dodder 10 ~ 30 parts, folium lycii 10 ~ 15 parts, the tuber of dwarf lilyturf 10 ~ 15 parts, the fruit of glossy privet 10 ~ 15 parts, pipewort 10 ~ 15 parts, the root of herbaceous peony 10 ~ 15 parts, cassia seed 10 ~ 20 parts, the red sage root 10 ~ 20 parts, plantain seed 10 ~ 20 parts, 10 ~ 20 parts, Poria cocos, sealwort 10 ~ 20 parts, radix polygonati officinalis 10 ~ 20 parts, 10 ~ 20 parts, the fruit of Chinese magnoliavine.
3. the seed of Chinese dodder health protection tea clear liver and improved vision according to claim 1, is characterized in that, in described seed of Chinese dodder health protection tea, the parts by weight of various bulk drug comprise: the seed of Chinese dodder 10 ~ 40 parts, folium lycii 10 ~ 20 parts, the tuber of dwarf lilyturf 10 ~ 20 parts, the fruit of glossy privet 10 ~ 20 parts, pipewort 10 ~ 20 parts, the root of herbaceous peony 10 ~ 20 parts, cassia seed 10 ~ 15 parts, the red sage root 10 ~ 15 parts, plantain seed 10 ~ 15 parts, 10 ~ 15 parts, Poria cocos, sealwort 10 ~ 15 parts, radix polygonati officinalis 10 ~ 15 parts, 10 ~ 15 parts, the fruit of Chinese magnoliavine.
4. the seed of Chinese dodder preparation method of health care tea clear liver and improved vision according to any one of claims 1 to 3, it is characterized in that, its preparation method comprises the following steps:
A. the preparation of the seed of Chinese dodder;
B. the preparation of folium lycii;
C. the preparation of other raw materials;
D. the seed of Chinese dodder folium lycii prepared and other raw materials are mixed, disinfection by ultraviolet light is packed.
5. the preparation method of the seed of Chinese dodder health protection tea clear liver and improved vision according to claim 4, is characterized in that: in described step a, and ripe seed of Chinese dodder fruit of gathering in 9 ~ October, together cuts off with host, dry, lay seed, decontamination of winnowing with a dustpan, and cleans, dries; The seed of Chinese dodder of drying is put into 80-100 DEG C baking machine turning in fry 30-45 minute shaping, take out after naturally dries.
6. the preparation method of the seed of Chinese dodder health protection tea clear liver and improved vision according to claim 4, is characterized in that: in described step b, and cleaned by the fresh folium lycii collected, the airing time, at 7-12 hour, parches; The folium lycii that airing is good is put into the pot that completes and remove the blue or green 30-40 minute that completes at 80-120 DEG C, folium lycii taking-up after completing is dried in the shade afterwards naturally, put into large iron pan to knead, knead on first backward downwards, firmly want evenly, when filament leaf bar rope is comparatively tight, the baking machine turning in putting into 80-100 DEG C when becoming dark brown fry 30-45 minute shaping, naturally dries after taking out.
7. the preparation method of the seed of Chinese dodder health protection tea clear liver and improved vision according to claim 4, is characterized in that: in described step c, and other raw materials are put into large iron pan and stir-fried, when color start blackout, start little fire stir-fry 20-30 minute shaping; Naturally dry after taking out.
8. the preparation method of the seed of Chinese dodder health protection tea clear liver and improved vision according to claim 4, it is characterized in that: in described steps d, the seed of Chinese dodder prepared and the mixing of other raw materials, put into fragrance extracting machine Titian 30-40 minute, temperature controls in 70-100 DEG C, disinfection by ultraviolet light is packed, and naturally dries after taking out.
9. a preparation method for the seed of Chinese dodder health protection tea clear liver and improved vision according to any one of claims 1 to 3, is characterized in that, the preparation method of described seed of Chinese dodder health protection tea can also comprise the following steps:
A. the preparation of the seed of Chinese dodder;
B. particle made by other raw materials;
C. the seed of Chinese dodder prepared is mixed with other feed particles things, disinfection by ultraviolet light, dress bag.
10. the preparation method of the seed of Chinese dodder health protection tea clear liver and improved vision according to claim 9, is characterized in that, in described step b, all the other raw materials described are steeped in 10 times amount ethanol and soak more than 24 hours, No. 2 extracts each 1 ~ 2 hour, are merged and leave standstill by then heating and refluxing extraction 2 times, remove supernatant, merge extract, leave standstill 24 hours, remove supernatant, when to put into thickener reduced pressure concentration relative density be 80 DEG C 1.36 medicinal extract, stand for standby use; Then medicinal extract is added honey to be in harmonious proportion, put into granulator and granulate dry.
CN201410635818.0A 2014-11-12 2014-11-12 Semen cuscutae health tea capable of removing liver-fire for improving eyesight and preparation method thereof Pending CN104304595A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104824278A (en) * 2015-05-17 2015-08-12 邵明荣 Semen plantaginis health tea and preparation method thereof
CN104839839A (en) * 2015-03-30 2015-08-19 孙村镇中药材种植技术协会 Partially fermented ginkgo leaf and medlar juice for treating glaucoma and preparation method thereof
CN105079493A (en) * 2015-07-08 2015-11-25 青岛恒波仪器有限公司 Semen cassiae oral liquid with liver-fire removing and eyesight improving functions for liver-fire exuberance and method for preparing semen cassiae oral liquid
CN105746816A (en) * 2016-05-14 2016-07-13 福建金草生物集团股份有限公司 Plant substitutional tea capable of clearing liver and improving eyesight and preparation method thereof

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CN1382396A (en) * 2002-05-17 2002-12-04 胡文元 Process for preparing health-care tea
CN103007035A (en) * 2012-12-27 2013-04-03 青岛华仁信息技术开发有限公司 Liver-clearing and vision-improving boxthorn leaf traditional Chinese medicine tea and preparation method thereof
CN103749820A (en) * 2013-12-31 2014-04-30 青岛恒波仪器有限公司 Fried feather cockscomb seed tea capable of clearing liver and improving vision and preparation method for fried feather cockscomb seed tea

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Publication number Priority date Publication date Assignee Title
CN1382396A (en) * 2002-05-17 2002-12-04 胡文元 Process for preparing health-care tea
CN103007035A (en) * 2012-12-27 2013-04-03 青岛华仁信息技术开发有限公司 Liver-clearing and vision-improving boxthorn leaf traditional Chinese medicine tea and preparation method thereof
CN103749820A (en) * 2013-12-31 2014-04-30 青岛恒波仪器有限公司 Fried feather cockscomb seed tea capable of clearing liver and improving vision and preparation method for fried feather cockscomb seed tea

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104839839A (en) * 2015-03-30 2015-08-19 孙村镇中药材种植技术协会 Partially fermented ginkgo leaf and medlar juice for treating glaucoma and preparation method thereof
CN104824278A (en) * 2015-05-17 2015-08-12 邵明荣 Semen plantaginis health tea and preparation method thereof
CN105079493A (en) * 2015-07-08 2015-11-25 青岛恒波仪器有限公司 Semen cassiae oral liquid with liver-fire removing and eyesight improving functions for liver-fire exuberance and method for preparing semen cassiae oral liquid
CN105746816A (en) * 2016-05-14 2016-07-13 福建金草生物集团股份有限公司 Plant substitutional tea capable of clearing liver and improving eyesight and preparation method thereof

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Application publication date: 20150128