CN104288735A - 一种治疗高原反应的中药及其制备方法 - Google Patents

一种治疗高原反应的中药及其制备方法 Download PDF

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CN104288735A
CN104288735A CN201410564877.3A CN201410564877A CN104288735A CN 104288735 A CN104288735 A CN 104288735A CN 201410564877 A CN201410564877 A CN 201410564877A CN 104288735 A CN104288735 A CN 104288735A
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Abstract

本发明公开了一种治疗高原反应的中药,按照重量份的原料包括黄芪、西洋参、刺五加、红景天、虎杖苷、酸枣仁、黄精、麦冬、龙眼核、干姜、冬瓜皮、硬脂酸镁和红花,将各原料分别进行切片、干炒和粉碎预处理后,加入煮锅中进行煎煮,将多次煎煮的汁液进行混合过滤即得到药液。本发明能够补气、升血、安神、扩张血管,提高人体氧气吸收量,还可以抗疲劳、抗辐射、补虚弱、增强骨髓造血功能,可以有效缓解高原反应引起的头痛、食欲减退、倦怠、乏力和头晕等症状,为临床预防治疗高原反应症,缓解高原反应引起的各种症状提供了一个新选择。

Description

一种治疗高原反应的中药及其制备方法
技术领域
本发明涉及一种中药,具体是一种治疗高原反应的中药及其制备方法。
背景技术
高原反应,即高原病,指未经训练的人迅速进入3000m以上的高原地区,由于大气压中氧分压降低,机体对低氧环境耐受性降低,难以适应而造成缺氧,从而产生的各种病理性反应,是高原地区独有的常见病。常见的症状有头痛、失眠、食欲减退、疲倦、呼吸困难等。头痛是最常见的症状,常为前额和双颞部跳痛,夜间或早晨起床时疼痛加重。肺通气增加如用口呼吸,轻度活动等可使头痛减轻,头痛严重时可能有视力障碍,但眼底检查正常,另外,失眠,多梦,耳鸣,眩晕,精力不集中,判断能力下降等神经系统的症状也常发生。胃肠道的症状为消化不良,食欲不振,腹胀,严重者有恶心,呕吐,甚至腹痛。呼吸加深加快,胸闷,气短,呼吸困难常为劳力性,若静息时出现呼吸困难,是高原肺水肿的先兆。
发明内容
本发明的目的在于提供一种能够有效治疗高原反应的中药及其制备方法,以解决上述背景技术中提出的问题。
为实现上述目的,本发明提供如下技术方案:
一种治疗高原反应的中药,按照重量份的原料包括:黄芪30-50份、西洋参20-30份、刺五加10-20份、红景天10-20份、虎杖苷10-15份、酸枣仁5-10份、黄精5-8份、麦冬5-8份、龙眼核3-5份、干姜2-4份、冬瓜皮1-2份、硬脂酸镁1-2份、红花0.5-1份。
所述治疗高原反应的中药的制备方法,包括如下步骤:(1)按照重量份称取各原料;(2)将红景天洗净切片后在85-105℃下干炒15-20min;(3)将黄芪、西洋参、刺五加、虎杖苷、酸枣仁、黄精、麦冬、龙眼核、干姜、冬瓜皮和红花烘干;(4)将所有原料放入粉碎机中粉碎至80-100目;(5)放入煮锅内加入1.5-2.5倍的水微沸煮1-2h后取出汁液,重复煮2-3次;(6)将各次取出的汁液混合后通过20-30目的过滤网过滤,得到药液。
药理作用:黄芪:补气升阳、益卫固表、托毒生肌、利水消肿,能够增强免疫功能、增强机体耐缺氧及应激能力、促进机体代谢、改善心功能;西洋参:滋阴补气、宁神益智、清热生津、降火消暑,能够强化心肌及增强心脏之活动能力,强壮中枢神经,安定身心并恢复疲劳,对血压有调整作用,对肝脏有调节副肾上腺素之分泌,促进新陈代谢的作用;刺五加:镇痛、解热、抗炎、抗疲劳、抗癌,对中枢神经系统有兴奋、抑制和抗惊厥作用;红景天:补气清肺、益智养心、收涩止血、散瘀消肿、抗氧化,能增强运动耐力;虎杖苷:镇咳、去痰、平喘、抗菌、清除自由基、调血脂、降低胆固醇、具有改善微循环、抑制溶酶体酶的释放、抗氧化、阻止微循环中白细胞粘、降血脂、抗脂质过氧化、抗病原微生物的作用;酸枣仁:补肝、宁心、敛汗、生津、主治虚烦不眠、惊悸多梦、体虚多汗和津伤口渴,酸枣仁成分阿魏酸亦有抗氧化和消除自由基,降血脂及心血管调节作用;黄精:抗病原微生物、抗疲劳、抗氧化、抗病毒,主治脾胃虚弱、体倦无力;麦冬:养阴生津、润肺清心,用于肺燥干咳、阴虚痨嗽、喉痹咽痛、津伤口渴、内热消渴、心烦失眠、肠燥便秘,能提高心肌收缩率和耐缺氧率;龙眼核:行气散结、止血、燥湿、主疝气、瘰疬、创伤出血;干姜:温中逐寒、回阳通脉,中枢抑制、加强镇静催眠和对抗中枢兴奋药的作用;冬瓜皮:治肿胀、消热毒、利小便、清热利水、消肿;红花:活血通经、散瘀止痛,主治瘀滞腹痛、胸胁刺痛、跌打损伤、疮疡肿痛。
与现有技术相比,本发明的有益效果是:
本发明能够补气、升血、安神、扩张血管,提高人体氧气吸收量,还可以抗疲劳、抗辐射、补虚弱、增强骨髓造血功能,可以有效缓解高原反应引起的头痛、食欲减退、倦怠、乏力和头晕等症状,为临床预防治疗高原反应症,缓解高原反应引起的各种症状提供了一个新选择。
具体实施方式
下面将结合本发明实施例,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1
本发明实施例中,一种治疗高原反应的中药,按照重量份的原料包括:黄芪30份、西洋参20份、刺五加10份、红景天10份、虎杖苷10份、酸枣仁5份、黄精5份、麦冬5份、龙眼核3份、干姜2份、冬瓜皮1份、硬脂酸镁1份、红花0.5份。
所述治疗高原反应的中药的制备方法,包括如下步骤:(1)按照重量份称取各原料;(2)将红景天洗净切片后在85℃下干炒15min;(3)将黄芪、西洋参、刺五加、虎杖苷、酸枣仁、黄精、麦冬、龙眼核、干姜、冬瓜皮和红花烘干;(4)将所有原料放入粉碎机中粉碎至80目;(5)放入煮锅内加入1.5倍的水微沸煮1h后取出汁液,重复煮2次;(6)将各次取出的汁液混合后通过20目的过滤网过滤,得到药液。
实施例2
本发明实施例中,一种治疗高原反应的中药,按照重量份的原料包括:黄芪40份、西洋参25份、刺五加15份、红景天15份、虎杖苷12份、酸枣仁8份、黄精6份、麦冬6份、龙眼核4份、干姜3份、冬瓜皮1.5份、硬脂酸镁1.5份、红花0.8份。
所述治疗高原反应的中药的制备方法,包括如下步骤:(1)按照重量份称取各原料;(2)将红景天洗净切片后在95℃下干炒18min;(3)将黄芪、西洋参、刺五加、虎杖苷、酸枣仁、黄精、麦冬、龙眼核、干姜、冬瓜皮和红花烘干;(4)将所有原料放入粉碎机中粉碎至90目;(5)放入煮锅内加入2倍的水微沸煮1.5h后取出汁液,重复煮2次;(6)将各次取出的汁液混合后通过20目的过滤网过滤,得到药液。
实施例3
本发明实施例中,一种治疗高原反应的中药,按照重量份的原料包括:黄芪50份、西洋参30份、刺五加20份、红景天20份、虎杖苷15份、酸枣仁10份、黄精8份、麦冬8份、龙眼核5份、干姜4份、冬瓜皮2份、硬脂酸镁2份、红花1份。
所述治疗高原反应的中药的制备方法,包括如下步骤:(1)按照重量份称取各原料;(2)将红景天洗净切片后在105℃下干炒20min;(3)将黄芪、西洋参、刺五加、虎杖苷、酸枣仁、黄精、麦冬、龙眼核、干姜、冬瓜皮和红花烘干;(4)将所有原料放入粉碎机中粉碎至100目;(5)放入煮锅内加入2.5倍的水微沸煮2h后取出汁液,重复煮3次;(6)将各次取出的汁液混合后通过30目的过滤网过滤,得到药液。
实施例4
临床试验
(1)试验对象:采用本发明共治疗150例患者,其中男80例,女70例;年龄最大者70岁,年龄最小者16岁。
(2)诊断标准:头痛、头昏、恶心呕吐、心慌气短、胸闷胸痛、失眠、嗜睡、食欲减退、腹胀、手足发麻、脉搏显著增快、血压轻度或中度升高、口唇或手指发绀、眼睑或面部浮肿。
(3)治疗方法:每天饭后服用,一次服用量为100ml,2天一疗程。
(4)治疗标准
治愈:症状全部消失,身体康复,随访半月无复发;
好转:病症明显减轻,治疗期间症状基本消失,能正常生活及工作;
无效:用药前后症状无改变。
(5)治疗结果:患者150例病例中服药后多在2天后见效,2-3个疗程治愈;其中治愈128例,显效15例,有效5例,无效2例,总有效率达98.7%。
典型病例:
(1)许某,男,50岁,进入高原后头痛、头昏、恶心呕吐,无法进食,服用本发明中药制剂2个疗程后,上述症状明显好转,病症消除。
(2)施某,女,38岁,进入高原后腹胀、手足发麻、脉搏显著增快,服用本发明中药制剂1天,上述症状明显好转,腹胀减轻,脸色好转,继续服用2个疗程后,病症消失,大病痊愈。
(3)乔某,男,20岁,进入高原后血压中度升高、口唇发绀、眼睑或面部浮肿,服用本发明中药制剂1天,血压恢复正常,继续服用3个疗程后,病症痊愈。
本发明能够补气、升血、安神、扩张血管,提高人体氧气吸收量,还可以抗疲劳、抗辐射、补虚弱、增强骨髓造血功能,可以有效缓解高原反应引起的头痛、食欲减退、倦怠、乏力和头晕等症状,为临床预防治疗高原反应症,缓解高原反应引起的各种症状提供了一个新选择。
对于本领域技术人员而言,显然本发明不限于上述示范性实施例的细节,而且在不背离本发明的精神或基本特征的情况下,能够以其他的具体形式实现本发明。因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本发明的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内。

Claims (2)

1.一种治疗高原反应的中药,其特征在于,按照重量份的原料包括:黄芪30-50份、西洋参20-30份、刺五加10-20份、红景天10-20份、虎杖苷10-15份、酸枣仁5-10份、黄精5-8份、麦冬5-8份、龙眼核3-5份、干姜2-4份、冬瓜皮1-2份、硬脂酸镁1-2份、红花0.5-1份。
2.一种采用权利要求1所述的治疗高原反应的中药的制备方法,其特征在于,包括如下步骤:(1)按照重量份称取各原料;(2)将红景天洗净切片后在85-105℃下干炒15-20min;(3)将黄芪、西洋参、刺五加、虎杖苷、酸枣仁、黄精、麦冬、龙眼核、干姜、冬瓜皮和红花烘干;(4)将所有原料放入粉碎机中粉碎至80-100目;(5)放入煮锅内加入1.5-2.5倍的水微沸煮1-2h后取出汁液,重复煮2-3次;(6)将各次取出的汁液混合后通过20-30目的过滤网过滤,得到药液。
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Cited By (4)

* Cited by examiner, † Cited by third party
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CN104840920A (zh) * 2015-05-18 2015-08-19 彭婷婷 一种预防高原反应的中药制品及其制备方法
WO2020062912A1 (zh) 2018-09-25 2020-04-02 中国人民解放军总医院 一种嘧啶磺酰胺类衍生物的医药用途
WO2020062913A1 (zh) 2018-09-25 2020-04-02 中国人民解放军总医院 前列环素受体激动剂的医药用途
CN111000967A (zh) * 2019-12-26 2020-04-14 陕西克林维尔信息科技有限公司 一种专为儿童研发的抗高原反应的组合配方及制备方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104840920A (zh) * 2015-05-18 2015-08-19 彭婷婷 一种预防高原反应的中药制品及其制备方法
WO2020062912A1 (zh) 2018-09-25 2020-04-02 中国人民解放军总医院 一种嘧啶磺酰胺类衍生物的医药用途
WO2020062913A1 (zh) 2018-09-25 2020-04-02 中国人民解放军总医院 前列环素受体激动剂的医药用途
CN111000967A (zh) * 2019-12-26 2020-04-14 陕西克林维尔信息科技有限公司 一种专为儿童研发的抗高原反应的组合配方及制备方法

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