CN105362596A - 一种治疗肺气肿的中药及其制备方法 - Google Patents

一种治疗肺气肿的中药及其制备方法 Download PDF

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CN105362596A
CN105362596A CN201510982706.7A CN201510982706A CN105362596A CN 105362596 A CN105362596 A CN 105362596A CN 201510982706 A CN201510982706 A CN 201510982706A CN 105362596 A CN105362596 A CN 105362596A
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范明月
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Abstract

本发明公开了一种治疗肺气肿的中药及其制备方法，所述中药由下述重量份数的药材制成：首乌藤6-19份，山药3-12份，洪连5-15份，千斤拔4-19份，卜芥7-18份，荆芥穗1-9份，甘草14-28份，九里明11-23份，白芥子5-19份，了哥王9-25份，委陵菜4-19份，五味子10-29份，十大功劳3-17份，川芎10-25份，紫苏子3-11份，牡丹皮5-15份，山萸肉10-24份，白芍9-20份。本发明组分均采用天然的中药原料，其配制简便、药源广、成本低，具有疗效显著、副作用小、成本低廉等优点。

Description

一种治疗肺气肿的中药及其制备方法
技术领域
本发明涉及一种治疗肺气肿的中药，属于医药技术领域。
背景技术
肺气肿是指终末细支气管远端（呼吸细支气管、肺泡管、肺泡囊和肺泡）的气道弹性减退，过度膨胀、充气和肺容积增大或同时伴有气道壁破坏的病理状态。按其发病原因肺气肿有如下几种类型：老年性肺气肿，代偿性肺气肿，间质性肺气肿，灶性肺气肿，旁间隔性肺气肿，阻塞性肺气肿。临床表现症状轻重视肺气肿程度而定。早期可无症状或仅在劳动、运动时感到气短，逐渐难以胜任原来的工作。随着肺气肿进展，呼吸困难程度随之加重，以至稍一活动甚或完全休息时仍感气短。此外尚可感到乏力、体重下降、食欲减退、上腹胀满。
目前，用于治疗肺气肿的药物较多，虽然能起到一定的作用，但其存在治疗效果较差、治疗时间长、副作用大、费用高等不足。
肺气肿是指终末细支气管远端(呼吸细支气管、肺泡管、肺泡囊和肺泡)的气道弹性减退，过度膨胀、充气和肺容积增大或同时伴有气道壁破坏的病理状态。肺气肿是常见病，是肺部的一种特殊病变，肺气肿的症状多样，轻重亦千差万别。目前治疗肺气肿常用抗感染、止咳、祛痰、平喘等药物，病人服药后，症状虽有所改善，但会产生依赖性，常年离不开药物，严重损害患者的身心健康。
中医认为，肺气肿多由心肺阴虚，阳亢动火，肺热气逆所致。故治宜清肺除热，养心健脾为主。
发明内容
本发明所要解决的技术问题是：提供一种治疗肺气肿的纯中药配方，该中药组合物配制方便、成本低、疗效显著、作用可靠、无副作用。
为解决上述技术问题，本发明采用的技术方案是：
本发明提供的治疗肺气肿的中药由下述重量份数的药材制成：首乌藤6-19份，山药3-12份，洪连5-15份，千斤拔4-19份，卜芥7-18份，荆芥穗1-9份，甘草14-28份，九里明11-23份，白芥子5-19份，了哥王9-25份，委陵菜4-19份，五味子10-29份，十大功劳3-17份，川芎10-25份，紫苏子3-11份，牡丹皮5-15份，山萸肉10-24份，白芍9-20份。
优选的，所述中药由下述重量份数的药材制成：首乌藤12份，山药9份，洪连10份，千斤拔11份，卜芥12份，荆芥穗5份，甘草20份，九里明17份，白芥子12份，了哥王15份，委陵菜11份，五味子20份，十大功劳10份，川芎17份，紫苏子7份，牡丹皮10份，山萸肉17份，白芍14份。
进一步的，所述中药由下述重量份数的药材制成：首乌藤19份，山药12份，洪连15份，千斤拔19份，卜芥18份，荆芥穗9份，甘草28份，九里明23份，白芥子19份，了哥王25份，委陵菜19份，五味子29份，十大功劳17份，川芎25份，紫苏子11份，牡丹皮15份，山萸肉24份，白芍20份。
进一步的，所述中药由下述重量份数的药材制成：首乌藤6份，山药3份，洪连5份，千斤拔4份，卜芥7份，荆芥穗1份，甘草14份，九里明11份，白芥子5份，了哥王9份，委陵菜4份，五味子10份，十大功劳3份，川芎10份，紫苏子3份，牡丹皮5份，山萸肉10份，白芍9份。
为了更好地表达本发明的中药组合物，本发明的中药组合物可以制备成临床上常用的剂型。比如，粉状制剂、散剂、丸剂、丹剂、膏剂、颗粒剂、口服液、糖浆、片剂、胶囊剂等制剂，所述药物制剂均可按照本领域技术人员所熟知的中药制剂制备方法制备得到。优选的，本发明中药组合物按照常规制备工艺制备成汤剂、片剂或胶囊剂。
本发明还提供了一种上述所述中药组合物的制备方法，其主要包含下述步骤：将所述配方量中药原料放入容器中，加冷水漫过药面，浸泡30分钟，再加水没过药面约6厘米，进行煎煮。武火煎煮，文火煎煮30分钟；第二煎煮，加水没过药面约6厘米，水沸后煎煮30分钟。两次煎煮取汁，合并得药液，分早晚两次服用。
服用方法：每日两次，饭后1小时后温服。10天为1个疗程。
有益效果：本发明是在传统中医理论和临床经验指导下，精选出各原料药及其配比，通过燥湿豁痰、行气开郁、补肺和胃、健脾益肾以治本，达到补元气、生津止渴、补气升阳、固表止汗、润肺化痰平喘，破气散结消积的效果，使病人的肺、脾、胃和肾的功能恢复正常，从而使咳、痰、喘等症状逐步缓解，逐步治愈；本发明组分均采用天然的中药原料，其配制简便、药源广、成本低，具有疗效显著、副作用小、成本低廉等优点。
具体实施方式
实施例1
本实施例的中药由下述重量份数的药材制成：首乌藤12份，山药9份，洪连10份，千斤拔11份，卜芥12份，荆芥穗5份，甘草20份，九里明17份，白芥子12份，了哥王15份，委陵菜11份，五味子20份，十大功劳10份，川芎17份，紫苏子7份，牡丹皮10份，山萸肉17份，白芍14份。
制备方法及使用方法：将所述配方量中药原料放入容器中，加冷水漫过药面，浸泡30分钟，再加水没过药面约6厘米，进行煎煮。武火煎煮，文火煎煮30分钟；第二煎煮，加水没过药面约6厘米，水沸后煎煮30分钟。两次煎煮取汁，合并得药液，分早晚两次服用。
服用方法：每日两次，饭后1小时后温服。10天为1个疗程。
实施例2
本实施例的中药由下述重量份数的药材制成：首乌藤19份，山药12份，洪连15份，千斤拔19份，卜芥18份，荆芥穗9份，甘草28份，九里明23份，白芥子19份，了哥王25份，委陵菜19份，五味子29份，十大功劳17份，川芎25份，紫苏子11份，牡丹皮15份，山萸肉24份，白芍20份。
制备方法及使用方法：将所述配方量中药原料放入容器中，加冷水漫过药面，浸泡30分钟，再加水没过药面约6厘米，进行煎煮。武火煎煮，文火煎煮30分钟；第二煎煮，加水没过药面约6厘米，水沸后煎煮30分钟。两次煎煮取汁，合并得药液，分早晚两次服用。
服用方法：每日两次，饭后1小时后温服。10天为1个疗程。
实施例3
本实施例的中药由下述重量份数的药材制成：首乌藤6份，山药3份，洪连5份，千斤拔4份，卜芥7份，荆芥穗1份，甘草14份，九里明11份，白芥子5份，了哥王9份，委陵菜4份，五味子10份，十大功劳3份，川芎10份，紫苏子3份，牡丹皮5份，山萸肉10份，白芍9份。
制备方法及使用方法：将所述配方量中药原料放入容器中，加冷水漫过药面，浸泡30分钟，再加水没过药面约6厘米，进行煎煮。武火煎煮，文火煎煮30分钟；第二煎煮，加水没过药面约6厘米，水沸后煎煮30分钟。两次煎煮取汁，合并得药液，分早晚两次服用。
服用方法：每日两次，饭后1小时后温服。10天为1个疗程。
临床资料
1、一般资料
临床观察病例100例，年龄45～75岁。
2、用法用量
组合物中的组分用量根据患者的体重和年龄酌情增减。一天一剂，水煎两遍得药汁，每日两次，饭后1小时后温服。10天为1个疗程。
3、疗效标准：
(1)痊愈：咳嗽、胸闷、气短、呼吸困难等症状和体征消失；
(2)有效：咳嗽、胸闷、气短、呼吸困难等症状和体征减轻或明显减轻；
(3)无效：症状及体征无明显改善。
4、治疗效果
该临床观察病例中，服药3－10个疗程，痊愈72例，随访未见复发；有效25例，无效3例。治疗期间未发生毒副作用。
典型病例
病例1：梁某，男，58岁，患慢支肺气肿3余年，咳嗽喘憋、呼吸困难症状，服用实施例l所制中药3个疗程后，病人呼吸困难缓解，咳嗽、咳痰减轻，继续服用3个疗程后痊愈。
病例2：赵某，女，69岁，患慢支肺气肿十几多年，近几年发展为肺心病，多次出现病危现象，终日哮喘不止，四肢软弱无力，不思饮食，大汗淋漓，精神恍惚不定，身体瘦弱不堪，生活不能自理，服用本发明中药2个疗程后，症状明显好转，连继续服用2个疗程，身体逐渐康复，呼吸、饮食、活动都有明显改善，后继续服用本发明中药4个疗程，病状消失，痊愈。
病例3：桑某，女，60岁。诊断患了慢性支气管炎，后来转为肺气肿，呼吸困难、胸闷、咳嗽、咳痰、气喘。严重时，咳嗽、咳痰、气促加重，痰量增加，痰变脓性，伴有发热、肺部可闻密集的干湿啰音等。服用本发明中药组合物制备的药剂3个疗程，呼吸困难、胸闷、咳嗽、咳痰等症状减轻，继续服用4个疗程，痊愈。
病例4：春某:，男，69岁，患有支气管哮喘史12年，先喘烦满，不能平卧，痰多质稀，色白有沫，脉微细，经X光射线诊断为肺气肿；服用本发明的中药3个疗程后后，症状减轻，继续服用本发明的中药5个疗程后治愈。
以上实施例的说明只是用于帮助理解本发明的方法及其核心思想。应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，还可以对本发明进行若干改进和修饰，这些改进和修饰也落入本发明权利要求的保护范围内。

Claims (5)

1.一种治疗肺气肿的中药，其特征在于，所述中药由下述重量份数的药材制成：首乌藤6-19份，山药3-12份，洪连5-15份，千斤拔4-19份，卜芥7-18份，荆芥穗1-9份，甘草14-28份，九里明11-23份，白芥子5-19份，了哥王9-25份，委陵菜4-19份，五味子10-29份，十大功劳3-17份，川芎10-25份，紫苏子3-11份，牡丹皮5-15份，山萸肉10-24份，白芍9-20份。
2.根据权利要求1所述的中药，其特征在于，所述中药由下述重量份数的药材制成：首乌藤12份，山药9份，洪连10份，千斤拔11份，卜芥12份，荆芥穗5份，甘草20份，九里明17份，白芥子12份，了哥王15份，委陵菜11份，五味子20份，十大功劳10份，川芎17份，紫苏子7份，牡丹皮10份，山萸肉17份，白芍14份。
3.根据权利要求1所述的中药，其特征在于，所述中药由下述重量份数的药材制成：首乌藤19份，山药12份，洪连15份，千斤拔19份，卜芥18份，荆芥穗9份，甘草28份，九里明23份，白芥子19份，了哥王25份，委陵菜19份，五味子29份，十大功劳17份，川芎25份，紫苏子11份，牡丹皮15份，山萸肉24份，白芍20份。
4.根据权利要求1所述的中药，其特征在于，所述中药由下述重量份数的药材制成：首乌藤6份，山药3份，洪连5份，千斤拔4份，卜芥7份，荆芥穗1份，甘草14份，九里明11份，白芥子5份，了哥王9份，委陵菜4份，五味子10份，十大功劳3份，川芎10份，紫苏子3份，牡丹皮5份，山萸肉10份，白芍9份。
5.制备上述任一项权利要求所述的中药的方法，其特征在于，将所述配方量中药原料放入容器中，加冷水漫过药面，浸泡30分钟，再加水没过药面约6厘米，进行煎煮；武火煎煮，文火煎煮30分钟；第二煎煮，加水没过药面约6厘米，水沸后煎煮30分钟；两次煎煮取汁，合并得药液。
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梁可云等: "老昌辉主任辨治慢性阻塞性肺气肿经验介绍", 《辽宁中医药大学学报》 *

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