CN104288616A - Drug for rapid delectation of ewes and preparation method thereof - Google Patents

Drug for rapid delectation of ewes and preparation method thereof Download PDF

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Publication number
CN104288616A
CN104288616A CN201410498822.7A CN201410498822A CN104288616A CN 104288616 A CN104288616 A CN 104288616A CN 201410498822 A CN201410498822 A CN 201410498822A CN 104288616 A CN104288616 A CN 104288616A
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radix
massa medicata
medicata fermentata
achyranthis bidentatae
semen plantaginis
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CN104288616B (en
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孙自富
刘欣
曹荫
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
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  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a drug for rapid delectation of ewes and a preparation method thereof. The drug is mainly prepared from angelica, safflower, red peony root, radix achyranthis bidentatae and semen plantaginis according to a certain weight ratio. The drug disclosed by the invention has the functions of clearing away heat and toxic materials, eliminating stasis to resolve swelling, promoting lactation and removing stasis and activating blood to promote menstruation, and is good in rapid delectation effect of sucking ewes and free of toxic and side effect.

Description

Medicine of the quick delactation of a kind of ewe and preparation method thereof
Technical field
The present invention relates to the decoction for stopping milk secretion of a kind of suckling domestic animal, is specifically the medicine of the quick delactation of a kind of ewe, belongs to veterinary applications.
Background technology
The breeding cycle of ewe and farrowing rate are the fast development of flock of sheep and the key link of enterprise's culture benefit, the natural feeding cycle of current ewe is 3-4 month, long suckling causes ewe hormonal change and body constitution to decline, and still needs recovery to take good care of after wean, causes ewe only to produce a tire in 1 year.
Summary of the invention
Therefore, there is great demand in the medicine of people to quick delactation, up to now, also do not find about relevant report of the present invention, the present inventor through development test repeatedly, and through repeatedly measuring checking, finally successfully work out the medicine of quick delactation, thus complete the present invention.
Object of the present invention just there is provided the composition of medicine of the quick delactation of a kind of ewe, makes the quick galactopoiesis of ewe, enter next breeding cycle in advance with Chinese prescription, reaches and shortens the object that ewe breeding cycle one produces two tires per year.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Radix Angelicae Sinensis selected by medicine of the present invention, Flos Carthami, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Semen Plantaginis, Fructus Crataegi, Massa Medicata Fermentata, Herba Taraxaci, Fructus Hordei Germinatus carries out combining, each efficacy of drugs is made by these drug regimens to produce synergism, thus effectively can reach the effect of the quick delactation of wet sheep, Radix Angelicae Sinensis is wherein selected to be because its nature and flavor are sweet pungent, temperature, enter the heart, liver, spleen channel, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea is suffered from abdominal pain, mass in the abdomen knot is poly-, metrorrhagia, headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea , mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Select Radix Paeoniae Rubra to be because its nature and flavor are bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, control warm poison and go mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea , Epilepsy abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid, flat, enter liver, kidney channel, life uses dissipating blood stasis blood, subduing inflammation, controls gonorrhea, hematuria, amenorrhea , mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis is suffered from abdominal pain, sore throat, carbuncle, traumatic injury, ripe invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, four fertile contractures, flaccidity syndrome and arthralgia syndrome.Semen Plantaginis is selected to be that cold, enter kidney, urinary bladder channel, have diuretic, heat clearing away, improving eyesight, the function of eliminating the phlegm, controls urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, and arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view because its nature and flavor are sweet.Select Fructus Crataegi be because its nature and flavor acid sweet, tepor, enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, taenifugal function, controls meat Ji , mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, puerperal after-pains, lochiorrhea, children's breast food stagnate.Select Massa Medicata Fermentata to be because its nature and flavor sweet, acrid, warm, enter upright stone tablet, stomach warp, have invigorating the spleen and regulating the stomach, the function helped digestion in adjusting, controls retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, and postnatal blood stasis is suffered from abdominal pain, and children's's enlarged abdomen heavily fortified point is long-pending.Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Fructus Hordei Germinatus is selected to be that tepor, enters spleen, stomach warp, have and help digestion because its nature and flavor are sweet, and in, the function of the therapeutic method to keep the adverse QI flowing downwards, controls food stagnation and does not disappear, swollen distention and fullness in the abdomen, inappetence, and vomiting is had loose bowels, and mammary swelling does not disappear.
The consumption of drug regimen of the present invention is also that inventor obtains through groping summary in a large number, and the consumption of each prescription can obtain good effect within the scope of following weight
Radix Angelicae Sinensis 10-20g Flos Carthami 8-13g Radix Paeoniae Rubra 10-20g
Radix Achyranthis Bidentatae 20-30g Semen Plantaginis 8-13g Fructus Crataegi 8-15g
Massa Medicata Fermentata 8-12g Herba Taraxaci 8-12g Fructus Hordei Germinatus 100-150g
Preferable amount is
Radix Angelicae Sinensis 15g Flos Carthami 10g Radix Paeoniae Rubra 15g
Radix Achyranthis Bidentatae 25g Semen Plantaginis 10g Fructus Crataegi 10g
Massa Medicata Fermentata 10g Herba Taraxaci 10g Fructus Hordei Germinatus 120g
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Angelicae Sinensis: pick decontamination, clean, moistening, when slightly drying in the air even to inside and outside humidity, section is dried;
2, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
3, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
4, Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, go reed, cutting, dry;
5, Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
6, Fructus Crataegi: pick clean impurity, sieve enucleation;
7, Massa Medicata Fermentata: get wheat bran and sprinkle evenly in hot pot, cigarette of having waited, pours into Massa Medicata Fermentata, fry to yellow, take out, sieve removes wheat bran, cools;
8, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
9, Fructus Hordei Germinatus (parched): get wheat tooth and put micro-stir-fry extremely yellow in pot, taking-up cools.
Two, prepare
The Radix Angelicae Sinensis of described weight, Flos Carthami, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Semen Plantaginis, Fructus Crataegi, Massa Medicata Fermentata, Herba Taraxaci, Fructus Hordei Germinatus (parched) are put into decocting container, and add water 800ml, soaks after 20 minutes, intense fire boils, then uses slow fire boiling 20 minutes, filters, obtain decoction for stopping milk secretion medicinal liquid, be divided into two doses to take.
Medicine of the present invention has heat-clearing and toxic substances removing, removing blood stasis to reduce swelling, lactogenesis eliminating stagnation, the function of promoting blood circulation to restore menstrual flow, and for wet sheep, quick delactation is effective, has no side effect.
Detailed description of the invention
The beneficial effect of medicine of the present invention is set forth further below by way of test example.
1, physical data
1. test period: 1 day to 2013 August in 2013 on JIUYUE 20;
2. experiment quantity: goat plant selects the moderate just before giving birth she-goat of the growth of livestock 100 carefully from Taihe County, Anhui Province.
2, test method
Within latter 14 days, start to take decoction for stopping milk secretion medicinal liquid from ewe farrowing, every twice-daily, sooner or later take, each 1 dose, serveing on three days is a course for the treatment of.
3, bioassay standard
Effective: lactation amount is comparatively front reduces more than 2/3rds, and breast examination is slightly full, and maneuver extruding breast, has a small amount of milk to overflow.
Invalid: lactation amount is comparatively front to be reduced less than 1/3rd, and breast is full, extrudes breast by maneuver, and milk overflows more.
4, measurement result
After a course for the treatment of terminates, next day, checkout statistics added up effective 96, and invalid 4, total effective rate is 96%.
5, test effect
After accumulative existing 95 ewes farrowing of statistics on May 30th, 2014, two tires are cherished again.

Claims (3)

1. the quick delactation's of an ewe medicine, is characterized in that: it is made up of the crude drug in following weight range:
Radix Angelicae Sinensis 10-20g Flos Carthami 8-13g Radix Paeoniae Rubra 10-20g
Radix Achyranthis Bidentatae 20-30g Semen Plantaginis 8-13g Fructus Crataegi 8-15g
Massa Medicata Fermentata 8-12g Herba Taraxaci 8-12g Fructus Hordei Germinatus 100-150g.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Angelicae Sinensis 15g Flos Carthami 10g Radix Paeoniae Rubra 15g
Radix Achyranthis Bidentatae 25g Semen Plantaginis 10g Fructus Crataegi 10g
Massa Medicata Fermentata 10g Herba Taraxaci 10g Fructus Hordei Germinatus 120g.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Radix Angelicae Sinensis: pick decontamination, clean, moistening, when slightly drying in the air even to inside and outside humidity, section is dried;
(2) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(3) Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
(4) Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, go reed, cutting, dry;
(5) Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
(6) Fructus Crataegi: pick clean impurity, sieve enucleation;
(7) Massa Medicata Fermentata: get wheat bran and sprinkle evenly in hot pot, cigarette of having waited, pours into Massa Medicata Fermentata, fry to yellow, take out, sieve removes wheat bran, cools;
(8) Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
(9) Fructus Hordei Germinatus (parched): get wheat tooth and put micro-stir-fry extremely yellow in pot, taking-up cools;
(2) prepare
The Radix Angelicae Sinensis of described weight, Flos Carthami, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Semen Plantaginis, Fructus Crataegi, Massa Medicata Fermentata, Herba Taraxaci, Fructus Hordei Germinatus (parched) are put into decocting container, and add water 800ml, and soak after 20 minutes, intense fire boils, then uses slow fire boiling 20 minutes, filters, to obtain final product.
CN201410498822.7A 2014-09-25 2014-09-25 A kind of medicine of the quick delactation of ewe and preparation method thereof Expired - Fee Related CN104288616B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101259221A (en) * 2008-04-10 2008-09-10 孔祥雷 Milk withdrawal powder
CN102657798A (en) * 2012-05-11 2012-09-12 青岛绿曼生物工程有限公司 Compound propolis composition to increase lactation yield of livestock and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101259221A (en) * 2008-04-10 2008-09-10 孔祥雷 Milk withdrawal powder
CN102657798A (en) * 2012-05-11 2012-09-12 青岛绿曼生物工程有限公司 Compound propolis composition to increase lactation yield of livestock and preparation method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
张国增: "《中兽医防治禽病》", 28 February 2013 *
方钱主等: "自拟回乳汤回乳50例临床观察", 《中国乡村医药杂志》 *
王雨敏等: "中药回乳58例临床体会", 《时珍国医国药》 *
赵兰青等: "乳汁过多治验", 《新中医》 *

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