CN104288391A - Medicine composition for nursing after meniscectomy and preparation method for medicine composition - Google Patents
Medicine composition for nursing after meniscectomy and preparation method for medicine composition Download PDFInfo
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- CN104288391A CN104288391A CN201410605661.7A CN201410605661A CN104288391A CN 104288391 A CN104288391 A CN 104288391A CN 201410605661 A CN201410605661 A CN 201410605661A CN 104288391 A CN104288391 A CN 104288391A
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Abstract
The invention relates to a medicine composition for nursing after a meniscectomy and a preparation method for the medicine composition, and belongs to the field of orthopedic nursing. The medicine composition comprises a main material and an auxiliary material; the main material comprises the following components in parts by weight: 10-20 parts of beefwood-like clubmoss herb, 8-16 parts of gratiola officinalis, 15-25 parts of peperomia pellucida, 12-20 parts of lasia spinosa, 10-20 parts of Incarvillea arguta, 6-12 parts of rheum lidjiangense, 15-25 parts of pearly maesa, 9-16 parts of ficus virens root, 12-20 parts of lmpatiens leptocaulon, 11-18 parts of silene baccifera, 12-18 parts of laggera alata, 6-12 parts of hibiscus trionum and 10-15 parts of helicia formosana; the auxiliary material comprises the following components in parts by weight: 8-15 parts of lemon, 2-4 parts of composite vitamin and 0.3-0.5 part of polypeptide. The medicine composition is mainly used for auxiliary nursing cure after a meniscectomy, is reasonable in recipe, can activate blood circulation, relieve pain, conduct sterilization and disinfection, and increase blood circulation, has skin care function, is convenient to use, and has no toxic and side effect.
Description
Technical field
The present invention relates to pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy and preparation method thereof, belong to Orthopaedic nursing field.
Background technology
Meniscus is dentinal fibers cartilage in January, and be filled in femur and tibial prosthesis gap, have medial meniscus and lateral meniscus, its edge part is thicker, and with joint capsule compact siro spinning technology, central part is thin, in free state.Meniscus itself without blood supply, therefore often can not self-healing after meniscus injury.The blood fortune of meniscus itself is poor, and power of repairing is weak, once damage, be difficult to self-healing, as treated not in time, late period can cause traumatic arthritis.Therefore, be diagnosed as meniscus injury, discoid meniscus, meniscus cyst person should early stage excision.After excision, will be repaired by fibrocyte, form fibrous cartilage, replace meniscus function.As correct in processed, generally how not affect knee joint function.But also must point out: Meniscectomy is intraarticular operation, if dealt with improperly, can lead to complications and affect function of joint, so the postoperative recovery of Meniscectomy more and more comes into one's own, becomes the key factor affecting postoperative cure rate.By to the postoperative recovery of Meniscectomy, the postoperative life quality of patient can be improved.General patient can feel swelling after surgery, some patients there will be arthralgia at night, muscle has atrophy existing, and at present also not for the care drug that Meniscectomy is postoperative, patient is alleviate with the medicine of some pain relievings when there is pain more unbearably.Therefore, provide a kind of convenience, use safety, eutherapeutic care drug very urgent.Coordinate traditional acupuncture, take exercise in right amount, can effectively alleviate patient suffering, promote postoperative rehabilitation.
The present invention staff studies orthopaedics medicine for a long time, by constantly groping the relation between compatibility between different medical material, drug effect, toxic and side effects, and carry out conscientiously careful screening study, the product make every effort to obtain high-efficiency low-toxicity, being applicable to industrialized great production, product active constituent content is high, stable performance.
Summary of the invention
The object of the present invention is to provide the pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy, can effectively alleviate patient suffering, promote postoperative rehabilitation, use safety, prescription are reasonable, processing technology is easy.
The technical solution adopted in the present invention is: the pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy, comprise major ingredient and adjuvant, described major ingredient component and weight portion are: Lycopodium casuarinoides Spring 10-20 part, Rhizoma begoniae pedatifidae 8-16 part, Herba Peperomiae pellucidae 15-25 part, thorn taro 12-20 part, suona horn flower 10-20 part, Rheum forrestii Diels 6-12 part, Herba Maesae Prelarii 15-25 part, Radix fici lacoris 9-16 part, Impatiens leptocaulon Hook.f. 12-20 part, Cucubalus baccifer 11-18 part, Laggera alata (Roxb.) Sch.-Bip. 12-18 part, Herba hibisci trioni 6-12 part, Eumeces Chinensis eye 10-15 part, described adjuvant component and weight portion are: Fructus Citri Limoniae 8-15 part, compound vitamin 2-4 part, polypeptide 0.3-0.5 part.
Specifically, described major ingredient component and weight portion are: Lycopodium casuarinoides Spring 15 parts, Rhizoma begoniae pedatifidae 12 parts, Herba Peperomiae pellucidae 20 parts, thorn taro 16 parts, suona horn spend 15 parts, Rheum forrestii Diels 9 parts, Herba Maesae Prelarii 20 parts, Radix fici lacoris 12 parts, Impatiens leptocaulon Hook.f. 16 parts, Cucubalus baccifer 14 parts, Laggera alata (Roxb.) Sch.-Bip. 15 parts, Herba hibisci trioni 9 parts, Eumeces Chinensis eye 13 parts, described adjuvant component and weight portion are: 12 parts, Fructus Citri Limoniae, compound vitamin 3 parts, polypeptide 0.4 part.
Further, described compound vitamin is water soluble vitamins, comprises vitamin B complex (vitamin B1, B2, B6, etc.) and vitamin C.
Further, described polypeptide is the little peptide in Radix et Caulis Opuntiae Dillenii extract and Folium Ginkgo extract.
Another object of the present invention is the preparation method of the pharmaceutical composition providing the postoperative nursing of a kind of Meniscectomy, and it is characterized in that, concrete steps comprise:
(1) thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii are cleaned, section, grinds to form fine powder after drying, obtains mixing fine powders, for subsequent use;
(2) by suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring, by 50%-85% alcoholic solution reflux, extract, 1-3 time of 8-12 times of weight, each 0.5-1.5 hour, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) Fructus Citri Limoniae adopts extraction by steam distillation volatile oil, for subsequent use;
(4) Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. are smashed to pieces, add the water of 6-10 times of weight, decoct and extract 1-3 time, extraction time is 2-4 hour, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 60 ~ 70 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye are added decocting in water 1-3 time of 8-10 times amount, each extraction time 1-3 hour, collecting decoction, removes slag concentrated, adds 65%-75% alcohol and makes alcohol content be 55%-65%, leave standstill 24-48 hour, make precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mixed, stir, both Chinese medicine preparation of the present invention.
Further, in the preparation method of the pharmaceutical composition of the postoperative nursing of described Meniscectomy, the preparation of described Chinese medicine composition is honeyed pill, spray.
Further, the medicinal composition spray preparation method of the described postoperative nursing of a kind of Meniscectomy, comprises the following steps:
(1) thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii are cleaned, section, grinds to form fine powder after drying, obtains mixing fine powders, for subsequent use;
(2) by suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring, by 50%-85% alcoholic solution reflux, extract, 1-3 time of 8-12 times of weight, each 0.5-1.5 hour, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) Fructus Citri Limoniae adopts extraction by steam distillation volatile oil, for subsequent use;
(4) Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. are smashed to pieces, add the water of 6-10 times of weight, decoct and extract 1-3 time, extraction time is 2-4 hour, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 60 ~ 70 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye are added decocting in water 1-3 time of 8-10 times amount, each extraction time 1-3 hour, collecting decoction, removes slag concentrated, adds 65%-75% alcohol and makes alcohol content be 55%-65%, leave standstill 24-48 hour, make precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mix, stir, make liquid medicine, get it filled water and clear water 1:8 proportions, add a small amount of sodium carbonate and regulate pH value to 7.0, sterilizing, dress spray bottle, the spray of obtained medicament of the present invention.
Further, the preparation method of the pharmaceutical composition honeyed pill of the described postoperative nursing of a kind of Meniscectomy, comprises the following steps:
(1) thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii are cleaned, section, grinds to form fine powder after drying, obtains mixing fine powders, for subsequent use;
(2) by suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring, by 50%-85% alcoholic solution reflux, extract, 1-3 time of 8-12 times of weight, each 0.5-1.5 hour, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) Fructus Citri Limoniae adopts extraction by steam distillation volatile oil, for subsequent use;
(4) Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. are smashed to pieces, add the water of 6-10 times of weight, decoct and extract 1-3 time, extraction time is 2-4 hour, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 60 ~ 70 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye are added decocting in water 1-3 time of 8-10 times amount, each extraction time 1-3 hour, collecting decoction, removes slag concentrated, adds 65%-75% alcohol and makes alcohol content be 55%-65%, leave standstill 24-48 hour, make precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mix, stir, add appropriate Mel, be brewed into required paste, stick with paste with rice and adjust medicine, pill, packaging.
With method and consumption: spray is each sprays 2 times, 3 times on the one toward affected part
Honeyed pill 1 time 1 bag, 2-3 time on the one
Compared with prior art, technique effect of the present invention is embodied in:
The first, in selected major ingredient, Herba Lycopodii can expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral; Rhizoma begoniae pedatifidae can be invigorated blood circulation, diuretic, removing toxic substances; Herba Peperomiae pellucidae energy eliminating stasis to stop pain; Thorn taro can antiinflammatory, pain relieving, help digestion, stomach invigorating; Suona horn flower can anti-inflammatory analgetic, promoting blood circulation to remove blood stasis; Rheum forrestii Diels can promoting blood circulation and hemostasis, anti-inflammatory analgetic; The synthetism of Herba Maesae Prelarii energy is subsided a swelling; Removing the necrotic tissue and promoting granulation; Radix fici lacoris energy dredge the meridian passage, detumescence, parasite killing; Impatiens leptocaulon Hook.f. can be regulated the flow of vital energy, invigorate blood circulation, pain relieving; Cucubalus baccifer energy synthetism granulation promoting, eliminating stasis to stop pain, inducing diuresis to remove edema; Laggera alata (Roxb.) Sch.-Bip. can expelling wind and removing dampness, promoting blood circulation and detoxication, Herba hibisci trioni can heat-clearing and toxic substances removing, expelling wind and removing dampness, cough-relieving, diuresis, Eumeces Chinensis eye can dispelling, collateral-activating, relaxing muscles and tendons; These medicines have good curative effect for postoperative the produced swelling of meniscus, pain, inflammation, amyotrophy, skin ulceration etc.
The second, in selected adjuvant, a large amount of Fructus Citri Limoniae quintessence oil also had in Lemon fruit is all oxidized derivatives of alkene terpenoid, has effect that is clean and blood circulation promoting, also has certain skin-care effect; Vitamin B1 in compound vitamin, also known as antineuritic vitamin, can treat that inappetence, muscle weakness are unable, limbs pain and the symptom such as paraesthesia, edema; Vitamin B2 is riboflavin again, is slightly soluble in water, and in neutrality or acid solution, heating is stable, and its participates in the growth metabolism of cell, is the necessary nutrient of when injected organism tissue metabolism and reparation; Vitamin B6 acts predominantly on the blood, muscle, nerve, skin etc. of human body, has good active force to arthritis, acne, anemia, child's spasm, melancholy; Vitamin C is a kind of antioxidant, and protection health avoids the threat of free radical, and vitamin C is also a kind of coenzyme simultaneously, has anticancer, antioxidation; Radix et Caulis Opuntiae Dillenii extract has effect that is antibacterial, antiinflammatory; Folium Ginkgo extract have invigorate blood circulation, blood stasis dispelling, dredging collateral effect.
3rd, pharmacy security of the present invention is stablized, and major ingredient and adjuvant is organically combined, mutually coordinates between each composition, drug effect is added, have good facilitation to the nursing that Meniscectomy is postoperative, processing technology is easy, has no side effect, coordinate traditional acupuncture, appropriate exercise, effectively can alleviate patient suffering, promotes postoperative rehabilitation.Can effectively improve other symptoms such as arthritis, arthralgia, scapulohumeral periarthritis simultaneously.
Detailed description of the invention
Explain the present invention further below in conjunction with embodiment and test example, but content of the present invention is not limited to the following stated.
Specific embodiment
Embodiment 1:
The pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy, comprise major ingredient and adjuvant, described major ingredient component and weight portion are: Lycopodium casuarinoides Spring 15 parts, Rhizoma begoniae pedatifidae 12 parts, Herba Peperomiae pellucidae 10 parts, thorn taro 16 parts, suona horn spend 15 parts, Rheum forrestii Diels 9 parts, Herba Maesae Prelarii 20 parts, Radix fici lacoris 13 parts, Impatiens leptocaulon Hook.f. 16 parts, Cucubalus baccifer 14 parts, Laggera alata (Roxb.) Sch.-Bip. 15 parts, Herba hibisci trioni 9 parts, Eumeces Chinensis eye 13 parts; Described adjuvant component and weight portion are: 12 parts, Fructus Citri Limoniae, compound vitamin 3 parts, polypeptide 0.4 part.
Its preparation method, comprises the following steps:
(1) take thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii by weight, clean, section, grinds to form fine powder after drying, obtains mixing fine powders, for subsequent use;
(2) suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring is taken by weight, by the 68% alcoholic solution reflux, extract, 2 times of 10 times of weight, each 1 hour, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) take Fructus Citri Limoniae by weight, adopt extraction by steam distillation volatile oil, for subsequent use;
(4) take Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. by weight, smash to pieces, add the water of 8 times of weight, decoct extraction 2 times, extraction time is 3 hours, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 65 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye is taken by weight, add the decocting in water 2 times of 9 times amount, 2 hours each extraction times, collecting decoction, remove slag concentrated, adding 70% alcohol makes alcohol content be 60%, leaves standstill 36 hours, makes precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mix, stir, make liquid medicine, get it filled water and clear water 1:8 proportions, add a small amount of sodium carbonate and regulate pH value to 7.0, sterilizing, dress spray bottle, the spray of obtained medicament of the present invention.
With method and consumption: spray is each sprays 2 times, 3 times on the one toward affected part
Embodiment 2
The pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy, comprise major ingredient and adjuvant, described major ingredient component and weight portion are: Lycopodium casuarinoides Spring 10 parts, Rhizoma begoniae pedatifidae 8 parts, Herba Peperomiae pellucidae 15 parts, thorn taro 12 parts, suona horn spend 10 parts, Rheum forrestii Diels 6 parts, Herba Maesae Prelarii 15 parts, Radix fici lacoris 9 parts, Impatiens leptocaulon Hook.f. 12 parts, Cucubalus baccifer 11 parts, Laggera alata (Roxb.) Sch.-Bip. 12 parts, Herba hibisci trioni 6 parts, Eumeces Chinensis eye 10 parts, described adjuvant component and weight portion are: 8 parts, Fructus Citri Limoniae, compound vitamin 2 parts, polypeptide 0.3 part.
Its preparation method, comprises the following steps:
(1) take thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii by weight, clean, section, grinds to form fine powder after drying, obtains mixing fine powders, for subsequent use;
(2) suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring is taken by weight, by the 50% alcoholic solution reflux, extract, 1 time of 8 times of weight, each 0.5 hour, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) take Fructus Citri Limoniae by weight, adopt extraction by steam distillation volatile oil, for subsequent use;
(4) take Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. by weight, smash to pieces, add the water of 6 times of weight, decoct extraction 1 time, extraction time is 2 hours, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 60 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye is taken by weight, add the decocting in water 1 time of 8 times amount, 1 hour each extraction time, collecting decoction, remove slag concentrated, adding 65% alcohol makes alcohol content be 55%, leaves standstill 24 hours, makes precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mix, stir, add appropriate Mel, be brewed into required paste, stick with paste with rice and adjust medicine, pill, packaging, both.
With method and consumption: honeyed pill 1 time 1 bag, 3 times on the one
Embodiment 3:
The pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy, comprise major ingredient and adjuvant, described major ingredient component and weight portion are: Lycopodium casuarinoides Spring 20 parts, Rhizoma begoniae pedatifidae 16 parts, Herba Peperomiae pellucidae 25 parts, thorn taro 20 parts, suona horn spend 20 parts, Rheum forrestii Diels 12 parts, Herba Maesae Prelarii 25 parts, Radix fici lacoris 16 parts, Impatiens leptocaulon Hook.f. 20 parts, Cucubalus baccifer 18 parts, Laggera alata (Roxb.) Sch.-Bip. 18 parts, Herba hibisci trioni 12 parts, Eumeces Chinensis eye 15 parts, described adjuvant component and weight portion are: 15 parts, Fructus Citri Limoniae, compound vitamin 4 parts, polypeptide 0.5 part.
Its preparation method, comprises the following steps:
((1) takes thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii by weight, cleans, and section, grinds to form fine powder after drying, obtain mixing fine powders, for subsequent use;
(2) suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring is taken by weight, by the 85% alcoholic solution reflux, extract, 3 times of 12 times of weight, each 1.5 hours, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) take Fructus Citri Limoniae by weight, adopt extraction by steam distillation volatile oil, for subsequent use;
(4) take Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. by weight, smash to pieces, add the water of 10 times of weight, decoct extraction 3 times, extraction time is 4 hours, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 70 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye is taken by weight, add the decocting in water 3 times of 10 times amount, 3 hours each extraction times, collecting decoction, remove slag concentrated, adding 75% alcohol makes alcohol content be 65%, leaves standstill 48 hours, makes precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mix, stir, add appropriate Mel, be brewed into required paste, stick with paste with rice and adjust medicine, pill, packaging, both.
With method and consumption: honeyed pill 1 time 1 bag, 2 times on the one
Clinical trial class: get 50 meniscectomy patients, in age 18-60 year, uses the postoperative care drug of Meniscectomy of the present invention, after 1 month, there are 18 examples to return to one's perfect health, have 25 routine symptoms obviously to alleviate, invalid 7 examples, overall efficiency reaches 86%, use after 3 months, have 30 examples to return to one's perfect health, have 17 routine symptoms obviously to alleviate, invalid 3 examples, total effective rate reaches 94%.
Patient 1: poplar, man, 20 years old, sprains during because playing soccer, lateral meniscus is impaired, do partial meniscectomy operation, all felt swelling, pain always, spray pharmaceutical composition described in the embodiment of the present invention 1, after two months, symptom is clearly better, and pain fades away, and walking also has more freely.
Patient 2: Liu, female, 36 years old, met with a traffic accident before 2 years, leg joint is fractured, and meniscus is impaired, treat and carried out meniscectomy procedure, after 1 year, substantially normally can walk, but always understand feels pain when squatting down, take pharmaceutical composition described in this embodiment 22 months, symptom is clearly better, and after taking 3 months, symptom disappears completely.
Patient 3: Korea Spro, man, 59 years old, because having neither sons nor daughters, within 3 years, last individual is engaged in excessive physical work, and action is excessive, and knee joint joint is impaired, do Partial Resection meniscal procedure, in past 2 years, sometimes still can feel that lower limb closes the evening of swelling, pain, particularly rainy day, with regard to hurt like hell, take pharmaceutical composition described in the embodiment of the present invention 3 after 1 month, the symptom of patient is clearly better, and continues to have taken 2 months, be almost recovered now, more painless, swelling sense, walking freely.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (6)
1. the pharmaceutical composition of the postoperative nursing of Meniscectomy, it is characterized in that, comprise major ingredient and adjuvant, described major ingredient component and weight portion are: Lycopodium casuarinoides Spring 10-20 part, Rhizoma begoniae pedatifidae 8-16 part, Herba Peperomiae pellucidae 15-25 part, thorn taro 12-20 part, suona horn flower 10-20 part, Rheum forrestii Diels 6-12 part, Herba Maesae Prelarii 15-25 part, Radix fici lacoris 9-16 part, Impatiens leptocaulon Hook.f. 12-20 part, Cucubalus baccifer 11-18 part, Laggera alata (Roxb.) Sch.-Bip. 12-18 part, Herba hibisci trioni 6-12 part, Eumeces Chinensis eye 10-15 part, described adjuvant component and weight portion are: Fructus Citri Limoniae 8-15 part, compound vitamin 2-4 part, polypeptide 0.3-0.5 part.
2. the pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy as claimed in claim 1, it is characterized in that, comprise major ingredient and adjuvant, described major ingredient component and weight portion are: Lycopodium casuarinoides Spring 15 parts, Rhizoma begoniae pedatifidae 12 parts, Herba Peperomiae pellucidae 20 parts, thorn taro 16 parts, suona horn spend 15 parts, Rheum forrestii Diels 9 parts, Herba Maesae Prelarii 20 parts, Radix fici lacoris 12 parts, Impatiens leptocaulon Hook.f. 16 parts, Cucubalus baccifer 14 parts, Laggera alata (Roxb.) Sch.-Bip. 15 parts, Herba hibisci trioni 9 parts, Eumeces Chinensis eye 13 parts, described adjuvant component and weight portion are: 12 parts, Fructus Citri Limoniae, compound vitamin 3 parts, polypeptide 0.4 part.
3. the preparation method of the pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy as claimed in claim 1, is characterized in that, comprise the following steps:
(1) thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii are cleaned, section, grinds to form fine powder after drying, obtains mixing fine powders, for subsequent use;
(2) by suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring, by 50%-85% alcoholic solution reflux, extract, 1-3 time of 8-12 times of weight, each 0.5-1.5 hour, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) Fructus Citri Limoniae adopts extraction by steam distillation volatile oil, for subsequent use;
(4) Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. are smashed to pieces, add the water of 6-10 times of weight, decoct and extract 1-3 time, extraction time is 2-4 hour, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 60 ~ 70 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye are added decocting in water 1-3 time of 8-10 times amount, each extraction time 1-3 hour, collecting decoction, removes slag concentrated, adds 65%-75% alcohol and makes alcohol content be 55%-65%, leave standstill 24-48 hour, make precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mix, stir, both Chinese medicine preparation of the present invention.
4. the preparation method of the pharmaceutical composition of the postoperative nursing of a kind of Meniscectomy as claimed in claim 3, is characterized in that, the preparation of described Chinese medicine composition is spray, honeyed pill.
5. the medicinal composition spray preparation method of the postoperative nursing of a kind of Meniscectomy as claimed in claim 4, is characterized in that, comprise the following steps:
(1) thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii are cleaned, section, grinds to form fine powder after drying, obtains mixing fine powders, for subsequent use;
(2) by suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring, by 50%-85% alcoholic solution reflux, extract, 1-3 time of 8-12 times of weight, each 0.5-1.5 hour, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) Fructus Citri Limoniae adopts extraction by steam distillation volatile oil, for subsequent use;
(4) Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. are smashed to pieces, add the water of 6-10 times of weight, decoct and extract 1-3 time, extraction time is 2-4 hour, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 60 ~ 70 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye are added decocting in water 1-3 time of 8-10 times amount, each extraction time 1-3 hour, collecting decoction, removes slag concentrated, adds 65%-75% alcohol and makes alcohol content be 55%-65%, leave standstill 24-48 hour, make precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mix, stir, make liquid medicine, get it filled water and clear water 1:8 proportions, add a small amount of sodium carbonate and regulate pH value to 7.0, sterilizing, dress spray bottle, the spray of obtained medicament of the present invention.
6. the preparation method of the pharmaceutical composition honeyed pill of the postoperative nursing of a kind of Meniscectomy as claimed in claim 4, comprises the following steps:
(1) thorn taro, Rheum forrestii Diels, Herba Maesae Prelarii are cleaned, section, grinds to form fine powder after drying, obtains mixing fine powders, for subsequent use;
(2) by suona horn flower, Radix fici lacoris, Lycopodium casuarinoides Spring, by 50%-85% alcoholic solution reflux, extract, 1-3 time of 8-12 times of weight, each 0.5-1.5 hour, merge extractive liquid, thickening filtration, it is for subsequent use that filtrate recycling ethanol obtains alcohol extract;
(3) Fructus Citri Limoniae adopts extraction by steam distillation volatile oil, for subsequent use;
(4) Rhizoma begoniae pedatifidae, Herba Peperomiae pellucidae, Impatiens leptocaulon Hook.f. are smashed to pieces, add the water of 6-10 times of weight, decoct and extract 1-3 time, extraction time is 2-4 hour, filters, merging filtrate, reclaim under reduced pressure is the thick paste of 1.05 ~ 1.20 to relative density under 60 ~ 70 DEG C of conditions, for subsequent use;
(5) Laggera alata (Roxb.) Sch.-Bip., Herba hibisci trioni, Eumeces Chinensis eye are added decocting in water 1-3 time of 8-10 times amount, each extraction time 1-3 hour, collecting decoction, removes slag concentrated, adds 65%-75% alcohol and makes alcohol content be 55%-65%, leave standstill 24-48 hour, make precipitation, merge, reclaim ethanol, decompression recycling ethanol, obtains mixed extract;
(6) thick paste of the extracting solution of the mixing fine powders of step (1), step (2) and step (4) is mixed, drying and crushing, add the mixed extract of volatile oil and the step (5) extracted in step (3), fully mix, stir, add appropriate Mel, be brewed into required paste, stick with paste with rice and adjust medicine, pill, packaging.
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Application publication date: 20150121 |