CN104288233A - Traditional Chinese medicine preparation for treating and preventing radiation damage and preparation method of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for treating and preventing radiation damage and preparation method of traditional Chinese medicine preparation Download PDFInfo
- Publication number
- CN104288233A CN104288233A CN201410481960.4A CN201410481960A CN104288233A CN 104288233 A CN104288233 A CN 104288233A CN 201410481960 A CN201410481960 A CN 201410481960A CN 104288233 A CN104288233 A CN 104288233A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- preparation
- medicine preparation
- ganoderma
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Insects & Arthropods (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to a traditional Chinese medicine preparation for treating and preventing radiation damage and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation for treating and preventing radiation damage comprises the following traditional Chinese medicine raw materials in parts by weight: 9-10 parts of astragalus membranaceus, 2.5-3 parts of Chinese angelica, 4-5 parts of ants, 4-5 parts of mulberries and 4-5 parts of lucid ganoderma. The traditional Chinese medicine preparation disclosed by the invention is good in effect in treating and preventing the radiation damage, simple in preparation process and easy for industrial production.
Description
Technical field
The present invention relates to a kind of being used for the treatment of and Chinese medicine preparation of pre-antiradiation injury and preparation method thereof.
Background technology
The harm of radiation to organism is larger, DNA, protein and enzyme can be directly acted on, ionization is caused to excite chemical bond rupture, molecule degeneration and cellularity are destroyed, also can act on hydrone in body, make it ionization occur and excite, produce a large amount of free radicals with Strong oxdiative performance, indirectly make histiocyte degeneration, necrosis, so that organism metabolic disorder, cause a series of pathological changes such as regulatory function obstacle of immunity, nerve and hormonal system.
For a long time, particular job personnel often accepting radiation prevent radiation damage by plumbous isolation, but the development of science and technology and radiation application is day by day extensive, the particularly extensive application in agricultural production, health care, scientific research and national defence due to nuclear energy and nuclear technology, the damage that radiation causes has become the major issue of people's growing interest.And radioprotective problem has been pushed to the unrestrained mouth of wind point by not long ago Fukushima, Japan nuclear leakage event especially.While nuclear power source brings benefit to the mankind, how to prevent and to alleviate the harm of Nuclear Accidents to health, research nuclear radiation injury means of prevention, positive searching is efficient, low toxicity, antiradiation drug easy to use have become a problem in the urgent need to address.
At present, the medicine of the Antiradiation damage studied both at home and abroad has ammonia coloured glaze base class compound (representing medicine is WR-2721), cytokine (GM-CSF, G-CSF, IL 26, EPO, KGF etc.), hormones (E838, Nilestriol, 5-AED), superoxide dismutase (SOD), metallothionein (MT), metal element chelate thing (Cu, Fe, Zn etc.), vitamins, potassium iodide, marine natural product (polypeptide from Chlamys farreri), single medicinal material (Radix Ginseng, Ganoderma, Bai Cailu alcohol and extract thereof) and compound Chinese medicinal preparation (Si Sheng decoction, radioprotective oral liquid, BUZHONG YIQI WAN etc.).Although antiradiation injury medicine research has in recent years achieved the achievement of attracting attention, still there is a lot of problem, as the toxicity, stability, effective time, route of administration, price, preservation etc. of medicine.In addition, radiation damage belongs to combined injury, and chemical drugs is generally for a certain paathogenic factor, and its treatment exists unicity.The nineties in 20th century, middle and late stage studied more anti-rad, these materials mainly opposing ray to the damage of healthy body, improve tumor cell to the sensitivity of radiation, repair damaged cell, eliminate free radical etc. in work.Initial research focuses mostly on the functional group of chemical method generation, along with going deep into of this kind of research, finds that it is also comparatively large to the murder by poisoning of healthy cell, and may bring out other pathological changes, therefore also just come on research steering natural materials.Chinese traditional herbs and some nourishing foods of China become object of study, achieve larger progress.But such research still rests on theory stage or laboratory stage so far, and the product that inefficacy is desirable.
Summary of the invention
Technical problem to be solved by this invention is, provides a kind for the treatment of to radiation damage and preventive effect is good, preparation technology is simple, be easy to being used for the treatment of and the Chinese medicine preparation and preparation method thereof of pre-antiradiation injury of suitability for industrialized production.
The present invention is used for the treatment of the Chinese medicine extraction composition comprising the Radix Astragali, Radix Angelicae Sinensis, Formica fusca, Fructus Mori, several Chinese medicine of Ganoderma with the Chinese medicine preparation of pre-antiradiation injury, and the weight proportion of each raw material of Chinese medicine is: Radix Astragali 9-10 part, Radix Angelicae Sinensis 2.5-3 part, Formica fusca 4-5 part, Fructus Mori 4-5 part, Ganoderma 4-5 part.
The preparation method of the above-mentioned Chinese medicine preparation of the present invention comprises the following steps:
A. get the Radix Astragali, Ganoderma, Formica fusca, take ethanol as solvent, heating and refluxing extraction Chinese medicinal ingredients, reclaims ethanol after extraction, obtains alcohol-extracted extract;
B. by the Radix Astragali after alcohol extraction, Ganoderma medicinal residues together with Fructus Mori, Radix Angelicae Sinensis, extracting in water Chinese medicinal ingredients, extracts and after filtering out medicinal residues, obtains Aqueous extracts; Aqueous extracts is concentrated, centrifugal, remove supernatant, obtain centrifugal liquid;
C. merge centrifugal liquid and alcohol-extracted extract, add correctives, spraying dry, granulation sterilizing, obtains granule.
In described step a, the mass concentration of ethanol solvent is 70%, heating and refluxing extraction 2 times, each 2 hours, filters, merging filtrate, reclaims ethanol, obtains alcohol-extracted extract;
The Radix Astragali, Ganoderma medicinal residues extracting in water three times together with Fructus Mori, Radix Angelicae Sinensis in described step b, first time adds the amount of 14 times of quality, and second and third time adds the amount of 12 times of quality, each 1.5 hours, filters, merges all filtrate, obtain Aqueous extracts.
Preparation of the present invention contains the multi-flavor medicines such as the Radix Astragali, Fructus Mori, Radix Angelicae Sinensis, Ganoderma, Formica fusca, has benefiting qi and nourishing blood, effect that kidney tonifying helps spleen, is mainly used in treatment anemia, leukopenia and the side effect of antagonism chemicotherapy etc.; The effect of its uniqueness shows: one is that said preparation proposes material foundation of tcm " component structure " hypothesis based on traditional Chinese medical science Overall View, is jointly made up of, has " three generating multi-dimension hierarchical structures " " active component+function ingredients ".Two be said preparation can eliminate irradiate in early stage blood exist organize the toxicant such as amine, peptide class, the immunologic function of enhancing body, delays the cytopathy that virus causes; Leukocyte and lymphocytic conversion after raising radiation damage, increase reticuloendothelial system phagocytic activity, and the immunologic function of protection and raising body, reduces the generation of radiation damage postoperative infection complication; Improve microcirculation and capillary permeability after radiation damage, alleviate and ooze out and inflammatory reaction.Three is that the reparation carried out body after radiation damage needs a long therapeutic procedure, and Chinese medicine is emphasized organic conception and focused on the internal balance of adjustment body, and Chinese medicine compound rehabilitation spirit is more suitable for the long-term treatment of Antiradiation injury.
The Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation.Modern study has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress and antibacterial action more widely.
Radix Angelicae Sinensis: enrich blood, invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Modern study has oxygen lack resistant function, conditioner body immunity function, has antitumaous effect.
Fructus Mori: nourishing YIN and supplementing blood, promote the production of body fluid moisturize, intestine moistening toxin expelling.The trace element of multiple needed by human can be supplemented, treatment anemia, cancer-resisting.
Ganoderma: Qi-benefiting and heart-nourishing, stasis-dispelling and pain-killing.Have protect the liver, antioxidation, delaying senility function, antiinflammatory, antitumor and immunoregulation effect.
Formica fusca: the kidney invigorating and essence nourishing; Dredge the meridian passage; Removing toxic substances and promoting subsidence of swelling.There is promotion metabolism, constitutional effect.
Detailed description of the invention
Below in conjunction with embodiment, technical scheme of the present invention is described further.
Embodiment:
1, medical material pre-treatment.Get the Radix Astragali, Radix Angelicae Sinensis, Formica fusca, Fructus Mori, Ganoderma, mass ratio is 10:3:5:5:5.
The Radix Astragali: removing impurity, cleans, runs through, cut sheet, dry, extracts for preparation.
Radix Angelicae Sinensis: removing impurity, cleans, runs through, shave, cold drying, extract for preparation.
Fructus Mori: removing impurity, dries, extracts for preparation.
Ganoderma: removing impurity, clean, shave, extracts for preparation.
Formica fusca: removing impurity, extracts for preparation.
2, get the Radix Astragali, Ganoderma, Formica fusca, with mass concentration 70% ethanol for solvent, heating and refluxing extraction 2 times, each 2 hours, filters, merging filtrate, reclaims ethanol, obtain alcohol-extracted extract; By the Radix Astragali (after alcohol extraction), Ganoderma (after alcohol extraction), Fructus Mori, Radix Angelicae Sinensis, extracting in water three times, first time adds 14 times amount, and second and third time adds 12 times amount, each 1.5 hours, filters, merges all filtrate.Aqueous extracts is concentrated, centrifugal, and remove supernatant, obtain centrifugal liquid, merge centrifugal liquid and alcohol-extracted extract, add correctives, spraying dry, granulation sterilizing, obtains compound granule.
Carry out pharmaceutical research to the granule of the embodiment of the present invention by experiment, result is as follows:
1. the blood tonification effect of pair hemorrhagic anemia model mice
The granule of the present embodiment is pressed the dosage gastric infusion of 100mg/kg, to the cytopenia of post hemorrhagic mice, hemoglobin reduces obvious rising effect, and mice frozen water swimming time obviously extends, and obviously extends post hemorrhagic mice normal pressure resistant anoxia life span.Showing that the mice anemia that this product causes losing blood has obvious blood tonification effect, increasing hemoglobin oxygen carrying capacity, extend life span, improve antifatigue effect and anti allergic reaction ability.
2. the blood tonification effect of pair chemical Anemia model mice
Mouse muscle injection acetylphenylhydrazine and intraperitoneal injection of cyclophosphamide make model of blood dificiency.The granule of the present embodiment is pressed the dosage continuous 15 days gastric infusions of 100mg/kg, the symptoms such as RBC, WBC, HGB in blood deficiency mouse peripheral blood liquid and the minimizing of bonemarrow nucleated cells number amount improve significantly, can the WBC of inhibition mice and index and spleen index obviously rebound simultaneously, the granule of prompting the present embodiment have lower acetylphenylhydrazine and cyclophosphamide chemical toxicity and nourish blood, the effect such as to enrich blood.
3. the preventive and therapeutic effect of pair normal mouse chemical leukopenia model
The granule of the present embodiment is pressed the dosage gastric infusion of 100mg/kg, the leukopenia cause normal injected in mice cyclophosphamide (Cy) and bonemarrow nucleated cells number reduce obvious therapeutical effect, shows that this product has obvious Attenuation to the hematotoxicity that normal injected in mice Cy causes.
4. the preventive and therapeutic effect of pair normal mouse radioactivity leukopenia model
The granule of the present embodiment is pressed the dosage gastric infusion of 100mg/kg, granule pair
60irradiate Co the HGB level that causes and RBC quantity reduce significant inhibitory action, reduces without obvious inhibitory action WBC number and Spleen coefficient.Result shows that this product is to normal mouse
60co has certain Attenuation after irradiating.
5. the synergism and attenuation after pair tumor-bearing mice chemotherapy
The granule of the present embodiment is pressed the dosage gastric infusion of 100mg/kg, the peripheral blood count reduction that S180 sarcoma mice causes after 5-FU chemotherapy through Cy chemotherapy, Lewis lung cancer solid tumor mice and H22 liver-cancer solid tumor mice is improved significantly, and RBC, WBC quantity and HGB level can be raised, there is obvious Attenuation.The bonemarrow nucleated cells number amount that this medicine causes Cy and 5-FU chemotherapy and Spleen coefficient reduce obvious inhibitory action.This product and Cy share, and fail to occur obviously suppressing S180 sarcoma to grow; Share with 5-FU and also fail to occur obviously suppressing Mice Bearing Lewis Lung Cancer solid tumor and H22 liver-cancer solid tumor to grow, this product and chemotherapy are share without obvious tumor suppression synergism.Result shows: this product to having certain Attenuation after tumor-bearing mice chemotherapy without potentiation.
6. the synergism and attenuation after pair tumor-bearing mice radiotherapy
The granule of the present embodiment is pressed the dosage gastric infusion of 100mg/kg, to H22 hepatocarcinoma tumor-bearing mice warp
60hGB level reduction caused by Co radiotherapy is significantly improved effect, and can raise RBC and WBC quantity, has obvious Attenuation.This medicine is to H22 tumor-bearing mice warp
60the Spleen coefficient that Co causes after irradiating reduces certain restitution.
7. on the impact of chemicotherapy Immune Function In Animals
The granule of the present embodiment is pressed the dosage gastric infusion of 100mg/kg, obvious regulating action is suppressed to the mouse immune that normal injected in mice cyclophosphamide (Cy) causes, can obviously raise blood hemolysin level, significantly can raise T lymphocyte acidαnaphthy acetate esterase, strengthen the lymphocyte transformation of PHA induction, and increase spleen, the thymus index of mice.Above result shows that this product all has remarkable inhibitory action to the cellular immunization caused by Cy model mice and humoral immune function decline.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine preparation with pre-antiradiation injury, it is characterized in that: the Chinese medicine extraction composition comprising the Radix Astragali, Radix Angelicae Sinensis, Formica fusca, Fructus Mori, several Chinese medicine of Ganoderma, the weight proportion of each raw material of Chinese medicine is: Radix Astragali 9-10 part, Radix Angelicae Sinensis 2.5-3 part, Formica fusca 4-5 part, Fructus Mori 4-5 part, Ganoderma 4-5 part.
2. be used for the treatment of the preparation method with the Chinese medicine preparation of pre-antiradiation injury described in claim 1, it is characterized in that: comprise the following steps,
A. get the Radix Astragali, Ganoderma, Formica fusca, take ethanol as solvent, heating and refluxing extraction Chinese medicinal ingredients, reclaims ethanol after extraction, obtains alcohol-extracted extract;
B. by the Radix Astragali after alcohol extraction, Ganoderma medicinal residues together with Fructus Mori, Radix Angelicae Sinensis, extracting in water Chinese medicinal ingredients, extracts and after filtering out medicinal residues, obtains Aqueous extracts; Aqueous extracts is concentrated, centrifugal, remove supernatant, obtain centrifugal liquid;
C. merge centrifugal liquid and alcohol-extracted extract, add correctives, spraying dry, granulation sterilizing, obtains granule.
3. be according to claim 2ly used for the treatment of the preparation method with the Chinese medicine preparation of pre-antiradiation injury, it is characterized in that: in described step a, the mass concentration of ethanol solvent is 70%, heating and refluxing extraction 2 times, each 2 hours, filters, merging filtrate, reclaims ethanol, obtains alcohol-extracted extract.
4. be according to claim 2ly used for the treatment of the preparation method with the Chinese medicine preparation of pre-antiradiation injury, it is characterized in that: the Radix Astragali, Ganoderma medicinal residues extracting in water three times together with Fructus Mori, Radix Angelicae Sinensis in described step b, add the amount of 14 times of quality for the first time, second and third time adds the amount of 12 times of quality, each 1.5 hours, filter, merge all filtrate, obtain Aqueous extracts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410481960.4A CN104288233A (en) | 2014-09-22 | 2014-09-22 | Traditional Chinese medicine preparation for treating and preventing radiation damage and preparation method of traditional Chinese medicine preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410481960.4A CN104288233A (en) | 2014-09-22 | 2014-09-22 | Traditional Chinese medicine preparation for treating and preventing radiation damage and preparation method of traditional Chinese medicine preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104288233A true CN104288233A (en) | 2015-01-21 |
Family
ID=52308345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410481960.4A Pending CN104288233A (en) | 2014-09-22 | 2014-09-22 | Traditional Chinese medicine preparation for treating and preventing radiation damage and preparation method of traditional Chinese medicine preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104288233A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147797A (en) * | 2015-08-20 | 2015-12-16 | 广州国宇医药科技有限公司 | Composition with anti-radiation function |
| CN105998476A (en) * | 2016-05-27 | 2016-10-12 | 李月升 | Chinese herbal compound capable of resisting radiation damage and preparation method therefor |
| CN107568740A (en) * | 2017-09-07 | 2018-01-12 | 哈尔滨医科大学 | A kind of health-care food composition, its preparation method and the purposes in terms of strengthen immunity |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101601812A (en) * | 2008-06-11 | 2009-12-16 | 黄刚 | A kind of nutrient that can strengthen human immunity and protecting heart and brain Autoscreen II enterocyte |
| CN102380016A (en) * | 2011-11-22 | 2012-03-21 | 中国人民解放军第三军医大学第二附属医院 | Anti-radiation traditional Chinese medicine composition |
| CN103859377A (en) * | 2012-12-10 | 2014-06-18 | 天津红日药业股份有限公司 | Formula and preparation method of life cultivation and health preservation food helpful for reducing radiation injury |
-
2014
- 2014-09-22 CN CN201410481960.4A patent/CN104288233A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101601812A (en) * | 2008-06-11 | 2009-12-16 | 黄刚 | A kind of nutrient that can strengthen human immunity and protecting heart and brain Autoscreen II enterocyte |
| CN102380016A (en) * | 2011-11-22 | 2012-03-21 | 中国人民解放军第三军医大学第二附属医院 | Anti-radiation traditional Chinese medicine composition |
| CN103859377A (en) * | 2012-12-10 | 2014-06-18 | 天津红日药业股份有限公司 | Formula and preparation method of life cultivation and health preservation food helpful for reducing radiation injury |
Non-Patent Citations (1)
| Title |
|---|
| 王宁等: "当归、黄芪及其有效成分抗辐射作用研究概况", 《中国辐射卫生》, vol. 17, no. 1, 31 March 2008 (2008-03-31), pages 121 - 122 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147797A (en) * | 2015-08-20 | 2015-12-16 | 广州国宇医药科技有限公司 | Composition with anti-radiation function |
| CN105998476A (en) * | 2016-05-27 | 2016-10-12 | 李月升 | Chinese herbal compound capable of resisting radiation damage and preparation method therefor |
| CN107568740A (en) * | 2017-09-07 | 2018-01-12 | 哈尔滨医科大学 | A kind of health-care food composition, its preparation method and the purposes in terms of strengthen immunity |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104288233A (en) | Traditional Chinese medicine preparation for treating and preventing radiation damage and preparation method of traditional Chinese medicine preparation | |
| CN101791025A (en) | Healthy tea | |
| CN109394850A (en) | It is a kind of to have effects that the Chinese medicine composition of delay skin aging and its water extract and fermentation material and application | |
| CN102604802B (en) | Preparation method of originally ecological bamboo-germanium nutritional wine | |
| CN103251741A (en) | Chinese medicine composition for treating toxoplasmosisinswine, and preparation method and application thereof | |
| CN102139021B (en) | Chinese medicinal preparation for preventing and treating radiation and preparation method thereof | |
| CN102078600B (en) | Anti-cancer compound ganoderma composition, application thereof and pharmaceutical composition containing same | |
| CN104225295A (en) | Composition for improving sleep, and preparation method and application thereof | |
| CN1985902B (en) | Chinese medicine for treating chronic hepatopathy | |
| CN113521221A (en) | Sealwort ointment traditional Chinese medicine prescription with monarch, minister, assistant and guide compatibility | |
| CN107854565A (en) | A kind of radiation-resistant Chinese medicine composition | |
| CN112220846A (en) | Traditional Chinese medicine composition for treating children's chronic cough and application thereof | |
| CN110038072A (en) | A kind of anti-tumor compositions and its application | |
| CN104825784B (en) | A kind of Chinese medicine composition with anti-gastric cancer activity and its preparation method and application | |
| CN1289104C (en) | Anticancer medicine and its preparation | |
| CN111388604B (en) | Traditional Chinese medicine composition for treating migraine and preparation method thereof | |
| CN102266434A (en) | Chinese medicinal composition for resisting tumor metastasis and preparation method thereof | |
| CN101444607A (en) | Method for preparing Chinese herbs to cure liver cancer | |
| CN106421154A (en) | Traditional Chinese medicine composition and traditional Chinese medicine preparation containing Chinese eaglewood wood and having cell repairing, anti-aging and anti-canter functions as well as preparation method of traditional Chinese medicine composition | |
| CN106511650A (en) | Traditional Chinese medicine composition for treating chronic rhinitis and preparation method thereof | |
| CN105770148A (en) | Preparing method for liver protecting and transaminase reducing capsules | |
| CN114767743A (en) | Chinese patent medicine containing red sage root for treating cardiovascular and cerebrovascular diseases and preparation process of Chinese patent medicine preparation | |
| CN112891456A (en) | Traditional Chinese medicine composition capable of improving and recovering human immunity | |
| CN102579883A (en) | Medicament-Shenxianling granules for preventing and treating cancers and preparation method of same | |
| CN101703568B (en) | Medicament for preventing and treating hepatitis B and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150121 |