CN104288232A - Process for processing magnolia officinalis based on method of steaming with rhizoma zingiberis recens juice - Google Patents
Process for processing magnolia officinalis based on method of steaming with rhizoma zingiberis recens juice Download PDFInfo
- Publication number
- CN104288232A CN104288232A CN201410574229.6A CN201410574229A CN104288232A CN 104288232 A CN104288232 A CN 104288232A CN 201410574229 A CN201410574229 A CN 201410574229A CN 104288232 A CN104288232 A CN 104288232A
- Authority
- CN
- China
- Prior art keywords
- rhizoma zingiberis
- zingiberis recens
- cortex magnoliae
- magnoliae officinalis
- oven
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a process for processing magnolia officinalis based on a method of steaming with rhizoma zingiberis recens juice. According to the process, the processed magnolia officinalis is obtained according to the steps of removing impurities and coarse peels of magnolia officinalis to be processed, cleanly washing, soaking, shredding, drying the shreds in a hot air circulating oven, uniformly mixing with ginger juice, then steaming in a steamer for 1-8 hours, subsequently drying in the oven till no moisture exists and finally cooling. Compared with the classic method of stir-baking with rhizoma zingiberis recens juice, the total of magnolol and honokiol of the processed magnolia officinalis prepared according to the process can reach 2.5 percent, the variation range is small, the production conditions are easily standardized, so that the process solves the problem of environment pollution caused by heavy smoke and dust during production of the processed magnolia officinalis based on the method of stir-baking with rhizoma zingiberis recens juice, and the processed magnolia officinalis prepared according to process for processing magnolia officinalis based on a method of steaming with rhizoma zingiberis recens juice has a better effect of restraining swelling.
Description
Technical field
The present invention relates to a kind of Cortex Magnoliae Officinalis processing procedure, particularly relate to a kind of Sucus Zingberis and steam method Cortex Magnoliae Officinalis processing procedure, adopt the Cortex Magnoliae Officinalis that this technique makes, have good effect to inhibitory rate of intumesce.。
Background technology
Cortex Magnoliae Officinalis is the dry dried bark of Magnoliacea plant Cortex Magnoliae Officinalis Magnolia officinalis Rehd. et Wils. or magnolia officinalis rehd.et wils.var.biloba rehd.et wils. Magnolia officinalis Rehd. et Wils. var. bilobaRehd. et Wils., root bark and branch skin.Cortex Magnoliae Officinalis is loaded in Shennong's Herbal, has another name called pachydermia, Cortex Magnoliae Officinalis, CORTEX MAGNOLIAE OFFICINALIS.Warm in nature, bitter in the mouth, pungent, there is dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards except full function.Raw product nature and flavor are high strong, and have the effects such as antibacterial, antiinflammatory, anti-gastric-ulcer, antioxidation, Cortex Magnoliae Officinalis life, with pungent, has the side effect of " sour jujube people mouthpiece ", clinically less raw use, can eliminate the zest to throat after processed with Rhizoma Zingiberis Recens, can strengthen the effect of alleviating distention in middle-JIAO stomach function regulating simultaneously.The concocting method of Cortex Magnoliae Officinalis is various, and Cortex Magnoliae Officinalis successive dynasties concocting method has clean system, cutting, parch, several large class of adjuvant system, more than l6 kind concocting method.In fact the processed with Rhizoma Zingiberis Recens method various places also unification not to the utmost of Cortex Magnoliae Officinalis, have Sucus Zingberis to mix rear stir-fry, have Sucus Zingberis to mix rear steaming, boil after having Sucus Zingberis to mix, and also has to mix Sucus Zingberis and stew to moisten rear direct oven dry, and above-mentioned preparation method all causes Cortex Magnoliae Officinalis mass discrepancy larger.Because CP method fried dry temperature is imprecise, in practical operation, the duration and degree of heating is difficult to control and cause smoke contamination comparatively serious.
Find to there is best proportion relation between medicine pair in addition in clinical practice.As Yang Yingyong etc., research discovery processed with Rhizoma Zingiberis Recens Fructus Evodiae is higher than the rutaecarpin content in Fructus Evodiae Rhizoma Zingiberis Recens compatibility by experiment, and when Fructus Evodiae and Rhizoma Zingiberis Recens compatibility, ratio more rutaecarpins content of Rhizoma Zingiberis Recens is fewer, and modern pharmacological research proves that rutaecarpin is Fructus Evodiae analgesic main component, therefore with the appropriate to the occasion processed with Rhizoma Zingiberis Recens Fructus Evodiae of Fructus Evodiae dispersing cold for relieving pain, and in side, the amount of compatibility Rhizoma Zingiberis Recens is unsuitable excessive.Visible, the ratio of the processed with Rhizoma Zingiberis Recens method of States Pharmacopoeia specifications is that 1:10 is not necessarily reasonable.
The Liu Yuanhui of Zhejiang Forestry Institute natural drug research and development centre etc., to the comparative study of the different processing technique of Medicinal Magnolia Bark, think that the optimised process of Rhizoma Zingiberis Recens stir-fry method is the Sucus Zingberis moistening 2 h fried dry at 120 DEG C with 10%; It is steam 3 h again, steaming temperature 100 DEG C after Sucus Zingberis moistening 2 h with 10% that Rhizoma Zingiberis Recens steams the optimised process of method; Two kinds of process results are compared, and the reserved that Rhizoma Zingiberis Recens fries the Medicinal Magnolia Bark effective ingredient that method obtains is relatively high.
A kind of novel concocting method of Cortex Magnoliae Officinalis(processed with ginger) is disclosed in CN201310277299.0, comprise the following steps: pretreatment of raw material, airtight accumulation diaphoresis, moistening is mixed thoroughly with Rhizoma Zingiberis Recens lixiviating solution, slow fire parch, moistening after diaphoresis, carry out frost with interval placement layer by layer again, adopt the Cortex Magnoliae Officinalis after the process of the method Chinese medicine processing method, active constituent content is high, and its surface occurs " Cortex Magnoliae Officinalis frost ".
Summary of the invention
The object of this invention is to provide a kind of Cortex Magnoliae Officinalis processing procedure, particularly Rhizoma Zingiberis Recens steams method Cortex Magnoliae Officinalis processing procedure, not only increases Medicinal Magnolia Bark effective ingredient, also solves traditional method of stir-baking with rhizoma zingiberis recens juice smoke contamination problem.
The present invention is realized by following technical step, and it is raw material with Cortex Magnoliae Officinalis, is prepared according to following steps:
(1) Cortex Magnoliae Officinalis chosen decontamination, scrape off rough bark, then clean, run through, shredding;
(2) Cortex Magnoliae Officinalis silk is dried in an oven;
(3) the Cortex Magnoliae Officinalis silk of oven dry is mixed thoroughly rear vexed leaching with Sucus Zingberis;
(4) put in steam box and steam;
(5) moisture is dried in an oven;
(6) product is obtained after cooling.。
In the technology of the present invention step (3), Sucus Zingberis used is preparation like this: first cleaned by Rhizoma Zingiberis Recens, mash, and adds water appropriate, squeezing extracting juice, and Rhizoma Zingiberis Recens dregs adds water and repeats squeezing in right amount once, merges juice, is " Sucus Zingberis ".
The technology of the present invention step (2) and (5) middle oven temperature are 80 DEG C;
The technology of the present invention step (2) and (5) middle baking oven are heated-air circulation oven;
In the technology of the present invention step (2) and (5), baking time is in an oven 3hr.
In the technology of the present invention step (3), the rear vexed leaching time mixed thoroughly by Sucus Zingberis is 1hr.
In the technology of the present invention step (4), in steam box, the steaming time is 1-6hr.
Treat in the present invention that process of preparing Chinese medicine Cortex Magnoliae Officinalis and Rhizoma Zingiberis Recens usage ratio are 1:10-3:10, be preferably 1.3:10.
Detailed description of the invention
Below by example, method provided by the invention is used, but do not limit the present invention in any form.
Embodiment 1
(1) stir-frying with ginger juice is standby.Get Rhizoma Zingiberis Recens 1kg, cleaned by Rhizoma Zingiberis Recens, mash, add 500ml hydraulic pressure extracting juice, Rhizoma Zingiberis Recens dregs adds 500ml water again and repeats squeezing in right amount once, merges juice, is " Sucus Zingberis ".
(2) preparation of Cortex Magnoliae Officinalis(processed with ginger) sample.Get 10kg Cortex Magnoliae Officinalis, choose decontamination, scrape off rough bark, clean, run through, shredding, put 80 DEG C of oven dry in heated-air circulation oven, for subsequent use.Investigate Magnolol and Honokiol total amount.
(3) Cortex Magnoliae Officinalis silk is added Sucus Zingberis, fully mix thoroughly, vexed leaching 1h, for subsequent use.Investigate Magnolol and Honokiol total amount.
(4) method of stir-baking with rhizoma zingiberis recens juice get 3.2.2 preparation under Cortex Magnoliae Officinalis silk, put in pot, use slow fire fried dry, cool.Investigate Magnolol and Honokiol total amount.
(5) steaming method mixed thoroughly by Sucus Zingberis.Get the Cortex Magnoliae Officinalis silk under (3) preparation, be placed in steam box and took out sample segment after 0,1,2,3,4,5,6 hour, be dried to dry in 80 DEG C of baking ovens, cool.Investigate Magnolol and Honokiol total amount.Result of the test is in table 1.
the change of table 1 different concocting method Magnolol and Honokiol total amount
Steaming method mixed thoroughly by Sucus Zingberis, and to steam Magnolol and Honokiol total amount amplitude of variation after 3 hours less, and content is the highest,
Embodiment 2
First cleaned by Rhizoma Zingiberis Recens 80g, mash, add water 80ml, squeezing extracting juice, and Rhizoma Zingiberis Recens dregs adds water and repeats in right amount to squeeze secondary, and remove slag merging juice, is diluted with water to 2000ml, makes concentration be 0.04g crude drug/ml.Get Cortex Magnoliae Officinalis 150g, add water 1200 ml, heating and refluxing extraction 3h, and extract 3 times, merge extractive liquid, is evaporated to runny plaste state, dissolves make concentration be 0.4g crude drug/ml with hot water 375ml.
Mice ear experiment is caused for model, the optimum proportioning of research Rhizoma Zingiberis Recens magnolia obovata alone and the antiinflammatory action that share and dosage with Oleum Tiglii.Oleum Tiglii causes mice ear experiment: Kunming mouse, male, is divided into 5 groups at random: contrast 0.5 % CMC-Na group, medicine SH group, positive controls ibuprofen Ibu (200 mg/kg).Gastric infusion, matched group gives equal-volume 0.5 % CMC-Na, every day 1 time, continuous 5 days.After last administration 1 h, 100 u1 Oleum Tiglii solution (Oleum Tiglii: ethanol: pyridine: ether=1:10:20:69) are evenly coated in mouse right ear tow sides, after 4 h, de-neck is put to death, ears are cut along auricle, sweep away along ear edge same area with the rustless steel circle punching of diameter 8 mm, scales/electronic balance weighing, using left and right two ear weight difference as swelling, calculates inhibitory rate of intumesce.Inhibitory rate of intumesce (%)=(the average swelling of matched group-average swelling of administration group) average swelling × 100 % of/matched group.
Embodiment 3
The empirically research method of example 2 Rhizoma Zingiberis Recens magnolia obovata solution preparation method and antiinflammatory action, changes the different dosage of Rhizoma Zingiberis Recens magnolia obovata, selects uniform designs table U5 (5
2). by Rhizoma Zingiberis Recens, Cortex Magnoliae Officinalis designs 5 levels respectively in effective dosage range, and arrange 5 kinds of different horizontal combination according to uniform designs table, namely carry out 5 groups of tests, uniform designs table and scheme are in table 2, table 3, and experimental result is in table 4.Research Rhizoma Zingiberis Recens magnolia obovata has optimum proportioning during best anti-inflammatory activity.
table 2 uniform designs table U5 (5
2
)
table, 3 uniform design schemes
| NO. | S (crude drug g/kg) | H (crude drug g/kg) | S 2 | H 2 | S*H |
| 1 | 0.1 | 2 | 0.01 | 4 | 0.2 |
| 2 | 0.2 | 4 | 0.04 | 16 | 0.8 |
| 3 | 0.3 | 1 | 0.09 | 1 | 0.3 |
| 4 | 0.4 | 3 | 0.16 | 9 | 1.2 |
| 5 | 0.5 | 5 | 0.25 | 25 | 0.25 |
| 6 | 0 | 5 | 0 | 25 | 0 |
| 7 | 0.5 | 0 | 0.25 | 0 | 0 |
Note: S: Rhizoma Zingiberis Recens; H: Cortex Magnoliae Officinalis
table 4 uniform design result
Note: S: Rhizoma Zingiberis Recens; H: Cortex Magnoliae Officinalis
By the Programming of EXECEL, try to achieve the functional relationship between the dosage of Rhizoma Zingiberis Recens Cortex Magnoliae Officinalis and antiinflammatory inhibition.
Y = 0.6284167 S-1.368195S2+0.0436074H+0.0024408H2+0.205547 S*H 6S*H+0.2242621， R
2=0.99
Consider that Cortex Magnoliae Officinalis has certain toxicity, limiting mice Cortex Magnoliae Officinalis dosage is 3g/kg, and by the restriction of target function value, can obtain best proportioning is 0.4:3, is 1.3: 10, is different from the 1:10 of pharmacopeia.When proportioning is 0.4:3, optimal inhibition rate is 65.68%.
Experimental example 4
Cause on mice ear experimental model at experimental example 2 Oleum Tiglii, relatively 1.3:10(uniform design optimal proportion), 1:10(CP method proportioning), 1.5: 10 (Camphor tree side method proportionings), the maximum proportioning of 2.0:10() drug combination effect, the results are shown in Table 5.
Table 5 experiment show
Experimental result show, 1.3:10 is optimum proportioning, has the highest suppression ratio, and experiment value and theoretical value close.
Embodiment 3
With guinea pig skin irritation test for Research foundation, investigate irritating change of Cortex Magnoliae Officinalis before and after processed with Rhizoma Zingiberis Recens, determine the Attenuation of Rhizoma Zingiberis Recens to Cortex Magnoliae Officinalis.The dosage adopted is the optimum proportioning that uniform design draws.
(1). guinea pig skin prepares
After the sterilization of tested for Cavia porcellus district, with scalpel, guinea pig skin is scratched gently, the degree of being with oozing of blood, Cavia porcellus left and right sides skin damage should be made to hinder degree basically identical.
Grouping and administration: get each 15 of damaged skin Cavia porcellus, be divided into 3 groups at random, Cortex Magnoliae Officinalis of making a living respectively group, Cortex Magnoliae Officinalis(processed with ginger) group, Sucus Zingberis group, often organize 5, the method that administration takes consubstantiality self left and right sides to contrast, raw Cortex Magnoliae Officinalis, Cortex Magnoliae Officinalis(processed with ginger) normal saline suspension are given respectively by administration group in left side, and right side is coated with normal saline.With gauze and immobilization with adhesive tape, all single cage of Cavia porcellus is raised, to prevent drug wastage to greatest extent.After medicine fully contacts guinea pig skin 24 h, tested material is washed away with warm water, every 1,24,48,72 h record Cavia porcellus tested district skins without erythema and edema phenomenon, and judge to give birth to Cortex Magnoliae Officinalis, Cortex Magnoliae Officinalis(processed with ginger) to the stimulation degree of guinea pig skin by standards of grading and strength criterion.
(2) degree standards of grading are stimulated
Erythema is visible as 1 point reluctantly, and moderate erythema is 2 points, and Severe erythema is 3 points, and aubergine erythema also has eschar to be formed as 4 points; Edema is visible as 1 point reluctantly, and cutaneous protuberance profile knows to be 2 points, and it is 3 points that edema swells 1 mm2, and edema protuberance expansion 1 more than mm2 is 4 points.Reaction meansigma methods 0 ~ 0. 49 is nonirritant, and 0. 5 ~ 2. 99 is slight zest, and 3. 0 ~ 5. 99 is moderate zest, and 6. 0 ~ 8. 00 is strong and stimulating.
Table 6 different pharmaceutical guinea pig skin irritant reaction score value table
As known from Table 6, Cortex Magnoliae Officinalis has hypotoxicity, and has certain irritation effect, and this effect is by relaxing after processed with Rhizoma Zingiberis Recens.
Claims (9)
1. Rhizoma Zingiberis Recens steams a method Cortex Magnoliae Officinalis processing procedure, and it comprises the following steps:
(1) Cortex Magnoliae Officinalis chosen decontamination, scrape off rough bark, then clean, run through, shredding;
(2) Cortex Magnoliae Officinalis silk is dried in an oven;
(3) the Cortex Magnoliae Officinalis silk of oven dry is mixed thoroughly rear vexed leaching with Sucus Zingberis;
(4) put in steam box and steam;
(5) moisture is dried in an oven;
(6) product is obtained after cooling.
2. according to technique described in claim 1, stir-frying with ginger juice is standby is first cleaned by Rhizoma Zingiberis Recens, mashes, and adds water appropriate, squeezing extracting juice, and Rhizoma Zingiberis Recens dregs adds water and repeats squeezing in right amount once, merges juice, is " Sucus Zingberis ".
3. according to technique described in claim 1, it is characterized in that: the temperature in step (2) and (5) in baking oven is 80 DEG C.
4. according to technique described in claim 1, it is characterized in that: step (2) and (5) middle baking oven are heated-air circulation oven.
5. according to technique described in claim 1, it is characterized in that: in step (2) and (5), baking time is in an oven 3hr.
6. according to technique described in claim 1, it is characterized in that: the rear vexed leaching time mixed thoroughly by Sucus Zingberis is 1hr.
7. according to technique described in claim 1, it is characterized in that: in steam box, the steaming time is 1-6hr.
8. according to technique described in claim 2, it is characterized in that: process of preparing Chinese medicine Cortex Magnoliae Officinalis and Rhizoma Zingiberis Recens usage ratio are 1:10-3:10.
9. according to technique described in claim 2, it is characterized in that: concoct Cortex Magnoliae Officinalis and Rhizoma Zingiberis Recens usage ratio preferably 1.3:10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410574229.6A CN104288232B (en) | 2014-10-24 | 2014-10-24 | A kind of ginger steam bark of official magnolia processing procedure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410574229.6A CN104288232B (en) | 2014-10-24 | 2014-10-24 | A kind of ginger steam bark of official magnolia processing procedure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104288232A true CN104288232A (en) | 2015-01-21 |
| CN104288232B CN104288232B (en) | 2018-03-16 |
Family
ID=52308344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410574229.6A Active CN104288232B (en) | 2014-10-24 | 2014-10-24 | A kind of ginger steam bark of official magnolia processing procedure |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104288232B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535108A (en) * | 2016-02-22 | 2016-05-04 | 高枫 | Processing method for medicinal magnolia bark slices stir-baked with ginger juice |
| CN105616498A (en) * | 2016-02-22 | 2016-06-01 | 高枫 | Novel processing method for medicinal magnolia bark slices stir-baked with ginger juice |
| CN109453333A (en) * | 2018-12-28 | 2019-03-12 | 康美（北京）药物研究院有限公司 | A kind of concocting method of SEMEN TSAOKO medicine materical crude slice |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423340A (en) * | 2011-11-23 | 2012-04-25 | 四川新绿色药业科技发展股份有限公司 | Ginger magnolia bark formula particle and preparation method thereof |
| CN103285086A (en) * | 2013-07-04 | 2013-09-11 | 江西中医学院 | Novel processing method of gingered Mangnolia officinalis |
-
2014
- 2014-10-24 CN CN201410574229.6A patent/CN104288232B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423340A (en) * | 2011-11-23 | 2012-04-25 | 四川新绿色药业科技发展股份有限公司 | Ginger magnolia bark formula particle and preparation method thereof |
| CN103285086A (en) * | 2013-07-04 | 2013-09-11 | 江西中医学院 | Novel processing method of gingered Mangnolia officinalis |
Non-Patent Citations (2)
| Title |
|---|
| 刘元慧: "厚朴饮片不同加工工艺的比较研究", 《时珍国医国药》 * |
| 郭健，等。: "厚朴的炮制研究", 《中国试验方剂学杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535108A (en) * | 2016-02-22 | 2016-05-04 | 高枫 | Processing method for medicinal magnolia bark slices stir-baked with ginger juice |
| CN105616498A (en) * | 2016-02-22 | 2016-06-01 | 高枫 | Novel processing method for medicinal magnolia bark slices stir-baked with ginger juice |
| CN109453333A (en) * | 2018-12-28 | 2019-03-12 | 康美（北京）药物研究院有限公司 | A kind of concocting method of SEMEN TSAOKO medicine materical crude slice |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104288232B (en) | 2018-03-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102091203A (en) | External traditional Chinese medicine preparation for treating chronic wounds and preparation method thereof | |
| CN104225258B (en) | A kind of Chinese medicine composition promoting wound healing | |
| CN104288232A (en) | Process for processing magnolia officinalis based on method of steaming with rhizoma zingiberis recens juice | |
| CN102784244B (en) | Externally applied traditional Chinese medicine for treating breast lumps | |
| CN103690849B (en) | Be used for the treatment of the Chinese medicine preparation of Superficial Thrombotic Phlebitis | |
| CN102805844A (en) | Medicine for treating liver cancer | |
| CN104997900A (en) | Traditional Chinese medicine for treating meniere disease | |
| CN104840623A (en) | Traditional Chinese medicine combination for treating toxic heat flourishing type burn and preparation method thereof | |
| CN104324081A (en) | Corydalis tuber superfine powder and preparation method and application thereof | |
| CN104324261A (en) | Pharmaceutical composition for treating high blood sugar and preparation method of pharmaceutical composition | |
| CN103977367A (en) | Traditional Chinese medicament for treating qi-stagnation blood-aggregation type bedsore and preparation method thereof | |
| CN108721442B (en) | Traditional Chinese medicine composition and preparation for treating burns, scalds and diaper dermatitis and preparation method thereof | |
| CN107050160A (en) | It is a kind of be used to scalding, the preparation burnt and preparation method thereof | |
| CN106975049A (en) | A kind of Yi nationality drug composition of reducing blood pressure and blood fat | |
| CN105535866A (en) | Medicine for treating hyperlipidemia and preparation method thereof | |
| CN105434667A (en) | Composition for treating burns and scalds and preparation method of spray of composition | |
| CN104840616A (en) | Traditional Chinese medicine combination for treating abundant-heat yin impairment type burn and preparation method thereof | |
| CN109381556A (en) | A kind of composition that treating pernio, preparation method and applications | |
| CN115990203B (en) | A preparation containing folium Malloti Apeltae component for preventing and treating chronic atrophic gastritis and its application | |
| CN105125928A (en) | External ointment for treating scalds and preparation method | |
| CN106668704A (en) | Hui-nationality traditional Chinese medicine aralia root bark granules for treating gastric cancer and preparation method thereof | |
| CN105287977A (en) | Sweet basil herb and aloe composition and preparation as well as preparation method and application of sweet basil herb and aloe composition | |
| CN105521050A (en) | Heat clearing, swelling diminishing, blood activating and blood stasis removing patch with rhizoma coptidis and flos carthami | |
| CN104840696A (en) | Traditional Chinese medicine combination for treating qi and blood deficiency type burn | |
| CN104940635A (en) | Scald and burn traditional Chinese medicine compound for external use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Address after: 515000 Guangdong city of Shantou province Chaoshan road Jinyuan Industrial City seven area A2-A3 Applicant after: GUANGDONG HUIQUN CHINESE TRADITIONAL MEDICINE CO., LTD. Address before: 515000 Guangdong province Shantou Jinping Jinyuan Industrial Zone area Chaoshan road 6B3-2 Applicant before: GUANGDONG HUIQUN CHINESE TRADITIONAL MEDICINE CO., LTD. |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |