CN104258304A - 一种通经祛风活络消痛的药酒 - Google Patents
一种通经祛风活络消痛的药酒 Download PDFInfo
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- CN104258304A CN104258304A CN201410557377.7A CN201410557377A CN104258304A CN 104258304 A CN104258304 A CN 104258304A CN 201410557377 A CN201410557377 A CN 201410557377A CN 104258304 A CN104258304 A CN 104258304A
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- radix
- rhizoma
- medicated wine
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Abstract
公开了一种具有通经祛风、活络消痛功效的药酒,其活性成分由乳香、没药、鸡血藤、桃仁、红花、丝瓜络、海桐皮、伸筋草、木瓜、两面针、川乌、草乌、羌活、田三七、天仙子、血竭、黄芪、广木香、香附子、苏木、一枝蒿、南星、威灵仙、姜黄、泽兰、马钱子、独活、山奈、八角莲、千年健、白芷、北细辛、商陆、鸡屎藤、爬山虎、七叶一枝花、白芥子、川断、丹参、虎杖、川牛膝组成。该药酒临床用于缓解和治疗各种内外伤肿痛、风湿性炎症疾病。具有疗效好,毒性低,价格低廉的优点。
Description
技术领域
本发明属于中医药领域,涉及一种具有通经祛风、活络消痛功效的药酒。
背景技术
伤口治疗,通常需要进行抗炎消肿止痛,口服消炎药及静脉滴注消炎药如青霉素、阿奇霉素类等都存在给药不方便,全身用药副作用大的缺点。局部给药制剂具有一定的临床优势,常用的如红药水、紫药水因含有重金属,易于导致中毒反应。单纯酒精消毒虽然较常用,但毕竟酒精易于挥发,杀菌作用有限。伤口的愈合与恢复,是最终恢复健康的保证,一般的恢复方式就是依靠身体自行的循环代谢逐渐恢复,辅以各种补品以增强体质,助于回复。伤口在恢复过程中要去除炎性渗出和水肿对伤口的压力,促进局部组织血液循环的恢复,方能为伤口早日愈合创造条件。但现行在外伤恢复方面使用的药物较少,比如云南白药,仅能够用于创伤面较小的外伤。
中医认为类风湿关节炎多由风寒湿邪气乘虚侵入人体,或素有蕴热,风寒湿郁久化热,留滞经络,闭塞不通而成,若日久不愈,肝肾亏损,筋骨失于濡养,以致关节畸形僵硬。中医对于类风湿关节炎治疗的理论认为“风寒湿邪,痹阻经脉,致使经脉不通,不通则痛”,所以中药治疗即当以祛风散寒、解痉通络、活血化淤为目的,同时亦须温肾助阳、扶正固本,以达强筋壮骨、根除关节炎症之功效。而西医对于类风湿性关节炎的治疗上主张抗炎、免疫治疗,常用免疫抑制剂、激素及非甾体抗炎药综合治疗,但这些药物付作用较多,而且停药后复发率较高。
因此,针对内外伤及风湿炎症的治疗,关键就在于行气活血,气行血通则风去则则肿消痛止。本发明针对病理分析,基于祖国医学的强大积累,发明一种具有通经祛风、活络消痛功效的药酒。药酒作为一种传统的给药方式,其本身具有较好的抗菌作用,又有较强的药物溶出能力,且能刺激血液循环,加强药物吸收。制备,保存,使用方便。
技术内容
本发明的目在于提供一种具有通经祛风、活络消痛功效的药酒,该药酒临床用于缓解和治疗各种内外伤肿痛、风湿性炎症疾病。具有疗效好,毒性低,价格低廉的优点。
本发明中所述药酒“组合物成分”不包括作为给药载体的酒本身。
为实现上述目的,本发明的技术方案实施如下:
一种具有通经祛风、活络消痛功效的药酒,其特征在于由如下组合物成分组成:
乳香、没药、鸡血藤、桃仁、红花、丝瓜络、海桐皮、伸筋草、木瓜、两面针、川乌、草乌、羌活、田三七、天仙子、血竭、黄芪、广木香、香附子、苏木、一枝蒿、南星、威灵仙、姜黄、泽兰、马钱子、独活、山奈、八角莲、千年健、白芷、北细辛、商陆、鸡屎藤、爬山虎、七叶一枝花、白芥子、川断、丹参、虎杖、川牛膝。
本发明具有通经祛风、活络消痛功效的药酒,其制备方法如下:
按照既定比例选取炮制后中药材,置于酒瓮中,加入52度以上白酒,密封其口,7日后取酒精浸液使用。
本发明具有通经祛风、活络消痛功效的药酒,参考了多种医学药典,同时辅以多年临床应用的优化,克服了禁忌组合的问题,具体选用中药的药理学基础为:
乳香,性辛、苦、温。入心、肝、脾经。活血,行气、止痛。本品有较显著的镇痛作用。以乳香为首味药的子宫丸比多种抗菌素有更强烈的抑菌作用。
没药,味苦、辛,性温,无毒。主治胸腹瘀痛、痛经、经闭、症瘕、跌打损伤、痈肿疮疡、肠痈、目赤肿痛。有活血止痛、消肿生肌等功效。
鸡血藤,活血散瘀舒筋、养血调经。中医认为经络不通是引起癫痫发作的直接因素,而血瘀又是引起经络不通的主要原因之一,因此只重视除痰,不重视活血化瘀是不全面的。
桃仁,有活血祛瘀、润肠通便的功效,可用于经闭、痛经、癓瘕痞块、跌扑损伤、肠燥便秘等。
红花,性温,味辛,活血通经、散瘀止痛。
丝瓜络,有通经活络,解毒消肿的功效。
海桐皮,味辛、苦,性平。归肝、胃、肾经。祛风除湿;利水和中;活血解毒。
伸筋草,性味归经苦辛温,入肝经。祛风散寒.除湿消肿,舒筋活络。用于风寒湿痹,筋脉拘挛疼痈。治风寒湿痹,关节酸痛,屈伸不利,可与羌活、独活、桂枝、白芍等配伍;若肢体软弱,肌肤麻木,宜与松节、寻骨风、威灵仙等同用。治跌打损伤,瘀肿疼痛,多配苏木、红花、桃仁等活血通络药,内服外洗均可。
木瓜,味酸,性温,无毒。消暑解渴、润肺止咳。它特有的木瓜酵素能清心润肺还可以帮助消化、治胃病,它独有的木瓜碱具有抗肿瘤功效,对淋巴性白血病细胞具有强烈抗癌活性。木瓜还有较强的抗菌作用,对肺炎双球菌和结核杆菌亦有明显抑制作用。
两面针,味苦、辛,性平。行气止痛,活血化瘀,祛风通络。用于气滞血瘀引起的跌打损伤、风湿痹痛、胃痛、牙痛,毒蛇咬伤;外治汤火烫伤。
川乌,辛、苦,性热;有大毒。归心、肝、肾、脾经。祛风除湿,温经止痛。用于风寒湿痹、关节疼痛、心腹冷痛、寒疝作痛。用于治疗风寒湿痹、关节疼痛等病症。一般炮制后内服。生川乌酊外用能刺激皮肤,继而产生麻木感,故外用作某些神经痛及风湿的镇痛剂。1、抗炎作用:川乌总碱可显著抑制大鼠角叉菜胶、鲜蛋汤、组织胺以及5一羟色胺引起的足肿胀。2、扩血管、降压作用:川乌和乌头碱均可扩张血管,起一过性降压作用。3、川乌有镇痛、局麻作用:乌头碱系生物碱是其有效成分。
草乌,祛风除湿,温经,散寒止痛。
羌活:温肾助阳,纳气,止泻。散表寒,祛风湿,利关节,止痛。
田三七,性温,味辛,具有散淤止血,消肿定痛的功效。可用于治疗衄血、便血、崩漏、咯血、吐血、外伤出血、胸腹刺痛等症。而且田七中的黄酮类化合物具有改善心肌供血、增加血管弹性、扩张冠状动脉的功效,谷甾醇和胡萝卜甙能降血脂。常食三七,对冠心病、心绞痛有预防和治疗作用。《纲目》:止血,散血,定痛。金刃箭伤,跌扑杖疮,血出不止者,嚼烂涂,或为末掺之,其血即止。亦主吐血,衄血,下血,血痢,崩中,经水不止,产后恶血不下,血运,血痛,赤目,痈肿,虎咬,蛇伤诸病。《玉揪药解》:和营止血,通脉行瘀,行瘀血而敛新血。
天仙子,性温,味苦辛,入心、胃、肝三经。具有定痫、止痛的功效。
血竭,具有活血散瘀,定痛,止血生肌的功效。
黄芪,味甘,性微温。含皂甙、蔗糖、多糖、多种氨基酸、叶酸及硒、锌、铜等多种微量元素。能补脾益气,补肺固表,利尿消肿,排脓,敛疮生肌。有增强机体免疫功能、改善物质代谢、增强性腺功能、抗应激、延缓衰老、强心、调节血压、抗病毒性心肌炎、保肝、抗溃疡等作用。黄芪多糖和黄芪皂苷是其主要有效成分。医学上用于气虚乏力,食少便溏,中气下陷,久泻脱肛,气虚水肿,痈疽难溃,久溃不敛,内热消渴,慢性肾炎蛋白尿,糖尿病等疾病的治疗。
广木香,行气止痛;调中导滞。
香附子,回阳救逆,补火助阳,散寒止痛。
苏木,活血祛瘀,消肿定痛。如妇人血滞经闭,痛经,产后瘀阻心腹痛,产后血晕,痈肿,跌打损伤,破伤风。
一枝蒿,具有祛风解表;健胃消积;活血散瘀等功效。
南星,燥湿化痰,祛风止痉,散结消肿。
威灵仙,性味,苦辛,温,小毒。祛风除湿,通络止痛,消痰水,散癖积。治痛风、顽痹、腰膝冷痛,疟疾,癓瘕积聚,破伤风,扁桃体炎。祛风湿止痛:用于风湿痛。其性善行,能通行十二经络,故对全身游走性风湿痛尤为适宜。
姜黄,姜黄能行气破瘀,通经止痛。主治胸腹胀痛,肩臂痹痛,心痛难忍,产后血痛,疮癣初发,月经不调,闭经,跌打损伤。
泽兰,性微温,味苦、辛。活血化瘀,行水消肿。用于月经不调、经闭、痛经、产后瘀血腹痛、水肿。
马钱子,兴奋健胃,消肿毒,凉血。主治四肢麻木,瘫痪,食欲不振,痞块,痈疮肿毒,咽喉肿痛。
独活,辛、苦,微温。归肝、肾、膀胱经。祛风胜湿;散寒止痛。该品辛散苦燥,气香温通,功善祛风湿,止痹痛,为治风湿痹痛主药,凡风寒湿邪所致之痹证,无论新久,均可应用。
山奈,根茎入药,温中化湿,行气止痛。主治急性胃肠炎,消化不良,胃寒疼痛,牙痛,风湿关节痛,跌打损伤。
八角莲,清热解毒,化痰散结,祛瘀消肿。治痈肿,疔疮,瘰疬,喉蛾,跌打损伤,蛇咬伤。
千年健,味辛、微苦。性辛,温。小毒。归入肝;肾;胃经。具有祛风湿、舒筋活络、止痛、消肿等功效。能治风湿痹痛、肢节酸育、筋骨痿软、跌打损伤、胃痛、痈疽疮肿等。
白芷,味辛,性温。归肺、脾、胃经。祛风,燥湿,消肿,止痛。治头痛,眉棱骨痛,齿痛,鼻渊,寒湿腹痛,肠风痔漏,赤白带下,痈疽疮疡,皮肤燥痒,疥癣。
北细辛,祛风,散寒,行水,开窍。治风冷头痛,鼻渊,齿痛,痰饮咳逆,风湿痹痛。
商陆,祛痰,平喘,镇咳,抗菌,抗炎,利尿。治水肿,胀满,脚气,喉痹,痈肿,恶疮。
鸡屎藤,祛风除湿;消食化积;解毒消肿;活血止痛。
爬山虎,破瘀血、消肿毒。
七叶一枝花,清热解毒,消肿止痛。
白芥子,温肺豁痰利气,散结通络止痛。
川断,味苦;辛;性微温。归肝;肾经。补肝肾;强筋骨;调血脉;续折伤;止崩漏。用于肢节痿痹,损筋折骨,遗精,风湿痹痛。
丹参:性微寒,味苦,归心、肝经。功效:祛瘀止痛,活血通经,清心除烦。主治月经不调、经闭痛经、症瘕积聚、胸腹刺痛、热痹疼痛、疮疡肿痛、肝脾肿大、心绞痛。
虎杖,清热解毒,利胆退黄,祛风利湿,散瘀定痛,止咳化痰。
川牛膝,味苦、酸,性平。祛风药;活血祛瘀药。逐瘀通经,补肝肾,强筋骨,利尿通淋,引血下行。用于经闭,痛经,腰膝酸痛,筋骨无力,淋证,水肿,头痛,眩晕,牙痛,口疮,吐血,衄血。《本经》:主寒湿痿痹,四肢拘挛,膝痛不可屈,逐血气,能引诸药下行,筋骨痛风在下者,宜加用之。
本发明药酒药理实验,实验方案及结果如下:
参比药品:正骨水(广西玉林制药厂生产)
取小鼠30只,体重(26±2)g,雌雄均用,随机分为3组。即空白对照组、阳性对照组(正骨水)、药酒组。以50g重法码从40cm高处自由落下,击伤右后腿即开始外擦药物,间隔6小时给药擦拭一次,每天2次,药酒每次每只给1ml,阳性组每只以正骨水1ml。给药第1天后各取4只鼠,第2与第3天后各取3只鼠的右后腿置10%甲醛中固定,作病理切片观察,分别检验给药后第1天、第2天与第3天的效果,以同一批样本观察对照组与各给药组血肿吸收局部病变恢复情况,最后作出综合评论。病理变化是以正常对照组组织切片(未击伤)为标准,同一批样本在显微镜下比较各受伤小鼠右后腿给各种药与给药病理变化分轻、中与重作出评判,结果见表2。
表1:小鼠腿伤肿胀的消肿实验
实验结果表明,本发明药酒对小鼠足肿胀有明显的抑制作用。
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临床疗效
1.样本信息
样本均为各型内外伤肿痛,风湿痹症患者,病例45例。其中中男27例,女18例,年龄最小者8岁,年龄最大者67岁。
2.治疗方法
外用涂抹,根据病情每日2~3次,每次1~2毫升。
3.治疗结果
数年来使用该药酒治疗各种外伤肿痛,风湿痹症,结果显示本药酒,疗效显著,能快速消除临床症状,使用3~5天,可完全去掉抗炎消肿祛风西药,服药8~10天,临床症状基本可消除,恢复健康。
4.典型病例
(1)、患者刘某某,男,34岁。因小时候腿脚外伤无钱医治,现在变天时经常疼痛,多处求医未愈,后来我处医治,使用本发明药酒擦患处,一月而愈,后未复发。
(2)、患者郑某某,女,76岁。患腰痛十余年,劳累后更甚,经X光检查诊断腰椎骨质增生。2008年10月来我处求医求治,使用本发明药酒擦涂,43天后疼痛缓解,60天后疼痛消失,经X光检查,骨刺已消失,至今未发。
(3)、患者陈某某,男,15岁。因五年前从高空摔下二落下残疾,经人民医院治疗,表面痊愈,但经常疼痛难忍,检查显示体内炎症,肿大,长期服用消炎药,导致牙齿脱落,头晕,抵抗力差等多种副作用。后经人介绍来我处求医,应用本发明药酒500毫升,每天擦洗患处数次,嘱其防寒,持续使用一月而愈,患者甚是欢喜而多次深表感谢,介绍很多患者前来求助。
(4)、患者徐某某,男,50岁,渔民。因长期在水上捕捞,寒冷变天时,四肢关节疼痛,因其家庭困难无钱入医院求治。经亲友介绍而来我处求治,诊断发现其四肢关节肿胀,痛苦不堪,外用本发明药酒擦拭患处,日十余次,嘱其停止水上作业,经50余天治疗,疼痛大减,70余天后基本未发。
(5)、患者肖某某,女,76岁。经市级医院检查,患轻度脑梗,左侧手脚无力麻木,生活不能自理,经多方治疗,效果不佳。后经患者推荐来我处求医,经询问观察其病情,嘱其使用本发明药酒外擦患处,一天十余次,半月后,奇迹出现,麻木消失,患者能屈伸用勺能进食,嘱其继续外用,两月后基本生活能自理。
具体实施例
称取乳香22克、没药9克、鸡血藤7克、桃仁15克、红花17克、丝瓜络5克、海桐皮7克、伸筋草22克、木瓜10克、两面针3克、川乌5克、草乌7克、羌活22克、田三七11克、天仙子16克、血竭8克、黄芪14克、广木香6克、香附子3克、苏木7克、一枝蒿9克、南星17克、威灵仙12克、姜黄14克、泽兰9克、马钱子15克、独活11克、山奈23克、八角莲13克、千年健7克、白芷9克、北细辛11克、商陆17克、鸡屎藤6克、爬山虎12克、七叶一枝花4克、白芥子6克、川断12克、丹参9克、虎杖15克、川牛膝21克。置于酒瓮中,加入56度二锅头白酒5斤,密封其口,7日后取酒精浸液使用。
用法:外用涂抹,根据病情每日2~3次,每次1~2毫升。本发明药液,不宜口服,阴虚火旺、各种热证患者及孕妇禁用。
Claims (1)
1.一种具有通经祛风、活络消痛功效的药酒,其特征在于由如下组合物成分组成:乳香、没药、鸡血藤、桃仁、红花、丝瓜络、海桐皮、伸筋草、木瓜、两面针、川乌、草乌、羌活、田三七、天仙子、血竭、黄芪、广木香、香附子、苏木、一枝蒿、南星、威灵仙、姜黄、泽兰、马钱子、独活、山奈、八角莲、千年健、白芷、北细辛、商陆、鸡屎藤、爬山虎、七叶一枝花、白芥子、川断、丹参、虎杖、川牛膝。
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CN105169225A (zh) * | 2015-08-17 | 2015-12-23 | 哈尔滨膳宝酒业有限公司 | 一种佛肚花祛风解表酒及其制备方法 |
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