CN104257859A - 一种治疗疣的药物 - Google Patents

一种治疗疣的药物 Download PDF

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CN104257859A
CN104257859A CN201410534283.8A CN201410534283A CN104257859A CN 104257859 A CN104257859 A CN 104257859A CN 201410534283 A CN201410534283 A CN 201410534283A CN 104257859 A CN104257859 A CN 104257859A
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radix
parts
wart
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张雅静
李敬文
李小群
严亚木
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Abstract

本发明的治疗疣的药物，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份组成；其具有原料易得，成本低，治疗效果显著等优点。

Description

一种治疗疣的药物
技术领域
本发明涉及一种中药,特别涉及一种治疗皮肤病中药方剂。 
背景技术
在医学上，皮肤病是有关皮肤的疾病，是严重影响人民健康的常见病、多发病之一，如麻风、疥疮、真菌病、皮肤细菌感染等。皮肤病是皮肤(包括毛发和甲)受到内外因素的影响后，其形态、结构和功能均发生变化，产生病理过程，并相应的产生各种临床先后表现。皮肤病的发病率很高，多比较轻，常不影响健康，但少数较重甚至可以危及生命。皮肤做为人体的第一道生理防线和最大的器官，时刻参与着机体的功能活动，维持着机体和自然环境的对立统一，机体的任何异常情况也可以在皮肤表面反映出来。很多皮肤病是内脏疾病的外在表现，即很多皮肤病变，其根本原因在内脏。例如：银屑病、白癜风、过敏性痒疹、红斑狼疮、内脏癌肿的皮肤表现等等，既是与细胞分裂异常、致病微生物感染及其产生的毒素、机体代谢紊乱、免疫功能失衡、内分泌紊乱、自由基毒素代谢障碍，甚至与精神、神经系统的病理变化有着间接或直接的关系。皮肤具备着近乎完美的生理保护功能：如屏障作用、感觉作用、调节体温、吸收作用、分泌和排泄作用等，在维护机体的健康，起到十分重要的作用。皮肤病是皮肤感染病与过敏性皮肤炎占大部分，不过随着老化的退行性变化之老人性皮 肤病，皮肤癌等也是重要的皮肤病，另外需注意因药物治疗疾病而引起副作用的各种皮肤障碍。我国人口多，患皮肤病的病人也多。其治疗使用最多的是外用药。如果外用药选择或使用不当，往往无效，甚至使病情加重。皮肤病具体来说，应注意以下几个方面：相同的药物有不同的剂型，如溶液、糊剂、粉剂、霜剂、洗剂、软膏、酊剂和乳剂等。不同的剂型，有不同的作用和适应证，故应根据不同病期的临床症状和皮损特点，正确选用不同剂型的外用药。一般急性期局部红肿、水疱、糜烂时，多选用溶液湿敷，可起到消炎、散热作用；有渗液者，先用溶液湿敷，后用油剂。皮损处于亚急性期时，红肿减轻，渗液减少，可酌情选用糊剂、粉剂和洗剂，可发挥消炎、止痒、收敛、保护作用。慢性期皮损增厚，呈苔藓样变时，目前以牛皮癣复发型专用药为主，防止牛皮癣、足癣、手癣等再次复发，牛皮癣复发型专用药主要外喷加涂抹，降低了对身体的副作用，它们穿透力强，作用持久，且有润滑及护肤作用。皮肤病很少危及生命，但顽固难愈。患者痛苦缠绵，医者焦头烂额，确是医学一大难题。 
经一般检索，没发现与本专利申请相同的方案。 
发明内容
本发明的目的在于：提出一种治疗疣的药物。 
本发明治疗的基本思路：皮肤病虽在皮肤肤节，却内连脏腑，并与情志变动、气血失和息息相关。一切皮肤病的根本原因，首先是整体气血失调，"邪之所凑，其气必虚"，然后风、寒、暑、湿、燥、火 六淫之邪，或长期接触有害物质，诸多外因趁虚袭人而致病。则治皮之道，首当着眼整体，从调燮五脏气血人手。设计其如下配方。 
本发明的治疗疣的药物，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份组成。 
本发明的治疗疣的药物制备方法，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份；经粉碎，包装，即得产品。 
包装：可为每小袋30g或每袋500克—1000克规格。 
用法：水煎服或将药粉30g倒入电热杯，加水200ml沸后十分钟，适温饮用，一日3次。 
本发明的治疗疣的药物制备方法，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇 床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份；采用现有技术的方法提取有效成份，制成粉状颗粒产品。 
本发明的治疗疣的药物制备方法，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份；采用现有技术的方法提取有效成份制成粉状颗粒产品，进而采用现有技术制成片剂或胶囊产品。 
原料及功效： 
生地(拉丁学名：Rehmannia glutinosa Libosch)，别名生地黄，为玄参科植物地黄的块根。具有清热凉血、益阴生津之功效。李时珍对生地黄的评价是：服之百日面如桃花，三年轻身不老。具有清热凉血功效用于温热病热入营血，壮热神昏，口干舌绛。如清营汤。 
蒺藜；功能主治；平肝解郁，活血祛风，明目，止痒。用于头痛眩晕，胸胁胀痛，乳闭乳痈，目赤翳障，风疹瘙痒。 
当归，拉丁文名：Angelica sinensis，别名干归、秦哪、西当归、岷当归、金当归、当归身、涵归尾、当归曲、土当归，它是多年生草本植物，其根可入药,是最常用的中药之一。补血和血，调经止痛，润燥滑肠。用于血虚，面色萎黄，眩晕心悸；血虚，或兼有瘀滞 的月经不调、经闭、痛经；虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤等痛证；肠燥便秘；久咳气喘。当归也可用于卤制品配料中，其主要特点是去腥增香，增加肉制品和药香味，也可食用。 
桂枝，正名：肉桂(学名：Cinnamomum cassia Presl)，又名玉桂、桂皮等，属樟目，樟科中等大乔木；其性味辛、甘，温，入肺、心、膀胱经，是主治里寒常用的温里药，具有补元阳、通血脉、暖脾胃之功效，常与补肝肾药、补气血药配伍，治疗肾阳不足、命门火衰、肢冷脉微，与其它温里药配伍治疗脘腹冷痛、寒痹腰痛，具有明显的镇痛和抗癌防癌的作用。现有的各种驱风油类药物如清凉油、风湿油等皆含有桂油成分。 
川芎(学名：Ligusticum chuanxiong hort)，是一种中药植物，常用于活血行气，祛风止痛，川芎辛温香燥，走而不守，既能行散，上行可达巅顶；又入血分，下行可达血海。活血祛瘀作用广泛，适宜瘀血阻滞各种病症；祛风止痛，效用甚佳，可治头风头痛、风湿痹痛等症。昔人谓川芎为血中之气药，殆言其寓辛散、解郁、通达、止痛等功能。本品辛温升散，凡阴虚阳亢及肝阳上亢者不宜应用；月经过多、孕妇亦忌用。[ 
红花，(拉丁学名：Carthamus tinctorius L.)，别名：红蓝花、刺红花，菊科、红花属植物，主产河南、湖南、四川、新疆、西藏等地。活血通经，散瘀止痛，有助于治经闭、痛经、恶露不行、胸痹心痛、瘀滞腹痛、胸胁刺痛、跌打损伤、疮疡肿痛疗效。有活血化瘀，散湿去肿的功效。 
牡丹皮，中药名。为毛茛科植物牡丹干燥根皮。产于安徽、四川、河南、山东等地。具有清热凉血、活血化淤、退虚热等功效。 
白鲜皮，别名：白藓皮、八股牛、山牡丹、羊鲜草，拉丁文名：CORTEX DICTAMNI中药名。性味：苦；咸；寒。归经：脾经；肺经；小肠经；胃经；膀胱经。功能：清热燥湿；祛风止痒；解毒。主治：风热湿毒所致的风疹；湿疹；疥癣；黄疸；湿热痹。 
川牛膝(学名：Cyathula officinalis Kuan)，又名牛膝，拐膝，天全牛膝，都牛胶等。根圆柱形，鲜时表面近白色，干后灰褐色或棕黄色。产四川、云南、贵州等地。根供药用，生品有下降破血行瘀作用，熟品补肝肾，强腰膝。 
蛇床子Cnidium monnieri(L.)Cuss.，正名为寸金草，别名野胡萝卜子，为伞形科植物蛇床的干燥成熟果实。夏、秋二季果实成熟时采收，除去杂质，晒干。性味：性温，苦。功能主治：温肾壮阳， 燥湿，祛风，杀虫。用于阳痿、宫冷、寒湿带下、湿痹腰痛；外治外阴湿疹、妇人阴痒、滴虫性阴道炎。 
狼毒(拉丁学名：Stellera chamaejasme Linn.)，别名川狼毒、续毒、绵大戟、山萝卜、闷花头、热加巴、一扫光、搜山虎、一把香、药罗卜、生扯拢、红火柴头花、猴子根、断肠草，瑞香科、狼毒属植物。狼毒的根系较大，生长于草原，是草原退化的标志。狼毒为瑞香科狼毒属，多年生草本或灌木。 
狼毒的毒性较大，可以杀虫；根入药，有祛痰、消积、止痛之功能，外敷可治疥癣。根还可提取工业用酒精，根及茎皮可造纸。功能 主治；逐水祛痰，破积杀虫。治水肿腹胀，痰、食、虫积，心腹疼痛，慢性气管炎，咳嗽，气喘，淋巴结、皮肤、骨、副睾等结核，疥癣，痔瘘。 
麻黄(学名：Ephedra sinica Stapf)，中药中的发散风寒药。 
蝉蜕，中药名，全形似蝉而中空，稍弯曲。长约4cm，宽约2cm。表面黄棕色，半透明，有光泽。头部有丝状触角1对，多已断落，复眼突出，颈部先端突出，口吻发达，上唇宽短，下唇伸长成管状。胸部背面呈十字形裂片，裂口向内卷曲，脊背两旁具有小翅2对；腹面有足3对，被黄棕色细毛。腹部钝圆，共9节。体轻，中空，易碎。无臭，味淡。功能：宣散风热、透疹利咽、退翳明目、祛风止痉。 
金银花；自古被誉为清热解毒的良药。它性甘寒气芳香，甘寒清热而不伤胃，芳香透达又可祛邪。金银花既能宣散风热，还善清解血毒，用于各种热性病，如身热、发疹、发斑、热毒疮痈、咽喉肿痛等症，均效果显著。[
皂刺；【功能主治】消毒透脓；搜风；杀虫。主痈疽肿毒；瘰疬；疮疹顽癣；产后缺乳；胎衣不下；疠风。 
防风；(学名：Saposhnikovia divaricata(Trucz.)Schischk.)，防风的根可生用。解表药、祛风药。功效：防风祛风解表、胜湿止痛、解痉、止痒，主治外感风寒、头痛身痛、风湿痹痛、骨节酸痛、腹痛泄泻、肠风下血、破伤风、风疹瘙痒。 
苦参(学名：Radix Sophorae flavescentis)为豆科苦参属的植物。别名：苦骨、地槐、水槐、菟槐、骄槐、野槐或白茎。分布于 俄罗斯、日本、印度、朝鲜以及中国大陆的南北各省区等地，生长于海拔1,500米的地区，多生在山坡、沙地、草坡、灌木林中及田野附近，目前尚未由人工引种栽培。功能主治：清热燥湿，杀虫，利尿。用于热痢，便血，黄疸尿闭，赤白带下，阴肿阴痒，湿疹，湿疮，皮肤瘙痒，疥癣麻风；外治滴虫性阴道炎。 
苍术：【性味归经】辛、苦，温。归脾、胃、肝经。 
甲珠是一种中药，还有炮甲珠、炮山甲等名。一般由鲮鲤(穿山甲)的鳞甲炮制后使用。炮制方法有烧、酥炙、醋炙、童便炙、油煎、土炒、蛤粉炒。其味咸，性微寒，归肝经、胃经。能活血散结、通经下乳、消痈溃坚。主血瘀经闭、症瘕、风湿痹痛、乳汁不下、痈肿、瘰疬等。气血虚弱、痈疽已溃者及孕妇禁服。 
本发明具有以下优点和效果：其具有原料易得，成本低，治疗效果显著等优点。 
具体实施方式
下面结合试验和临床试验情况，对本发明的技术方案进一步详细描述。 
在过去的几十年中，治疗了不少的病人。现列举典型病例如下： 
疣，赘生物，俗名"瘊子"，可出现于全身各部。现代分为传染性疣、扁平疣等。余曾治数十例疣症。皆自行脱落而愈。兹举一例： 
本发明的治疗疣的药物，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红 花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份；经粉碎，包装，即得产品。 
包装：可为每小袋30g或每袋500克—1000克规格。 
用法：水煎服或将药粉30g倒入电热杯，加水200ml沸后十分钟，适温饮用，一日3次。 
典型病例临床效果： 
刘XX，女，31岁，患左颊部、左手背扁平疣3年多，挑，刺，禁(以丝线扎紧瘊子根部，使之缺血坏死)，涂(鸭胆子)，内服中药数十剂，皆无效。日见增多，面部有黄褐斑，痛经，舌质紫暗，脉涩，黄带。断为湿热内蕴，瘀血内阻，营卫阻塞，不荣肌肤四末。服本发明药物15剂后，全部自行脱落，黄褐斑亦退净。 

Claims (4)

1.一种治疗疣的药物，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份组成。 
2.一种治疗疣的药物制备方法，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份；经粉碎，包装，即得产品。 
3.一种治疗疣的药物制备方法，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份；采用现有技术的方法 提取有效成份，制成粉状颗粒产品。 
4.一种治疗疣的药物制备方法，其特征在于：配方以重量计，由生地40-50份、当归100-150份，桂枝25-30份，川芎25-30份，红花25-30份，丹皮25-30份，白藓皮25-30份、首乌40-50份，蒺藜40-50份，麻黄15-20份，狼毒10-15份，川牛膝40-50份，蛇床子40-50份，蝉蜕25-30份，金银花60-80份，皂刺40-50份,防风25-30份，苦参40-50份，苍术40-50份，炮甲珠25-30份；采用现有技术的方法提取有效成份制成粉状颗粒产品，进而采用现有技术制成片剂或胶囊产品。 
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