Summary of the invention
Goal of the invention: the object of this invention is to provide a kind of aloe facial cleaner and preparation method thereof.
Technical scheme: the object of the invention is by following scheme realize:
A kind of aloe facial cleaner, be made up of the raw material of following weight portion: Aloe extract 2-4 part, geniposide 4-6 part, puerarin 3-5 part, Inokopolyose 5-7 part, cetyl sulfophenoxy benzenesulfonic acid disodium salt 20-30 part, coconut oil fatty acid monoethanolamide 10-15 part, N-cocamidopropyl propyl amide-DMG inner salt 30-36 part, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt 15-20 part, decanoyl/octanoyl glycerides 5-7 part, distilled water 150-180 part.
Described aloe facial cleaner, be made up of the raw material of following weight portion: Aloe extract 2-4 part, geniposide 4-6 part, puerarin 3-5 part, Inokopolyose 5-7 part, cetyl sulfophenoxy benzenesulfonic acid disodium salt 20-30 part, coconut oil fatty acid monoethanolamide 10-15 part, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt 30-36 part, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt 15-20 part, decanoyl/octanoyl glycerides 5-7 part, glutamic acid diacetic acid four sodium 2-4 part, succinyl glycyrrhetinic acid disodium 3-5 part, glucose fatty acid phosphate 2-4 part, hydroxypropyl phosphorate starch 1-3 part, distilled water 150-180 part.
The present invention can add chelating agen, described chelating agen is disodium EDTA, tetrasodium salt of EDTA, ethylenediamine tetramethylene phosphonic acid, hydroxymethyl phosphonic acid diethylester, diethylenetriamine penta sodium, hexapotassium, two hexene triamine five methylenephosphonic acids, diethylenetriamine pentamethylenophosphonic acid seven sodium salt, EDTMP six sodium salt, sodium ethylenediamine tetramethylenephosphonate, glutamic acid diacetic acid four sodium, succinyl glycyrrhetinic acid disodium, one in methyl-glycine diacetate tri-sodium and hydroxyethyl diamine tetraacethyl trisodium salt or its mixture.
The preparation method of described aloe facial cleaner, the preparation method of Aloe extract comprises the following steps: get fresh Aloe vera L.var. chinensis(Haw.)Berg. kind, peeling, by Aloe mesophyll homogenate, centrifugal, obtain Aloe juice, hydro-oxidation sodium adjust ph is 7.0-7.4, and spraying dry obtains Aloe extract.
Described aloe facial cleaner is preparing the application in skin-lightening cosmetic.
Aloe facial cleaner preparation method, containing following steps:
A) get Aloe extract, geniposide, puerarin, Inokopolyose respectively, cross 100 mesh sieves, mix homogeneously, adding distil water, stir 1-10min;
B) cetyl sulfophenoxy benzenesulfonic acid disodium salt, coconut oil fatty acid monoethanolamide, N-cocamidopropyl propyl amide-N is added, N-dimethylglycine inner salt, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, decanoyl/octanoyl glycerides, glutamic acid diacetic acid four sodium, succinyl glycyrrhetinic acid disodium, glucose fatty acid phosphate, hydroxypropyl phosphorate starch, be uniformly mixed.
Beneficial effect:
Aloe is commonly referred to as Aloe, originates in Mediterranean, Africa, is Liliaceae herbaceos perennial, and according to wild aloe kind kind more than 300 of textual criticism, be mainly distributed in the ground such as Africa, be a kind of Liliaceae herbaceous plant, it is perennial Liliaceae meat herbaceous plant.Containing abundant polysaccharide, protein, aminoacid, vitamin, organized enzyme and the trace element very useful to human body.Its characteristic component is Aloe anthraquinones etc., Aloe due to containing various bioactivators, at folks of china just by the natural drug as beauty treatment, hair care and treatment dermatosis, Folium Aloe clusters, in seat shape or be born in stem top, the normal lanceolar of leaf or leaf short wide, edge has sharp tooth to sting.Inflorescence is umbrella shape, total shape, spike, taper shape etc., and color is red, yellow or tool redness of the skin or complexion speckle, six, petal, gynoecium six pieces.The many Colaesces of perianth base portion become tubular.
The Aloe vera L.var. chinensis(Haw.)Berg. that the present invention uses is the mutation of Aloe vulgaris, has another name called the Chinese aloe aloe.Aloe vera L.var. chinensis(Haw.)Berg. stem is short, and leaf closely clusters, and seedling leaf becomes two row, and blade face blade back is adularescent speckle all.After leaf grows up to, white macula does not take off.Leaf is about 35 centimetres, wide 5-6 centimetre, plant likeness in form Aloe Barbadensis Miller.The Aloe vera L.var. chinensis(Haw.)Berg. individual plants in the south of Fujian Province is obviously little than Aloe Barbadensis Miller.The place of production: the provinces such as Fujian, Guangdong, Guangxi, Yunnan, Sichuan, Taiwan.Also have in In Yuanjiang Area, Yunnan Province, Hainan and island, Leizhou.There is certain medical value.The raw material that tender leaf can do Aloe salad eats.
Aloe main component: anthraquinone analog compound: aloin, aloe-emodin, different aloin, B aloin, produce the two glycoside of luxuriant growth emodin, aloe-emodin-8-glycoside, Aloearbonaside, Aloe resin B, alomycin, alochrysine, aloietic acid, aloaresic acid, aloresinotannol, aloxanthine, chrysophanol, chrysophanol monoglucoside, rear Mo Nate aloin, anthrol, different eleutherol glycoside, aloe saponaria glycoside I, II, helminthosporin, 7-hydroxyl aloin, tetrahydro anthracene Fructus Vitis viniferae glycoside.Carbohydrate: arabinose, galactose, glucose, mannose, rhamnose, xylose, alduronic acid, galacturonic acid, glucuronic acid, mannuronic acid, arabinose, cellulose, lignin.Aminoacid: galactosamine, glucamine amino acid alanine, lysine, proline, hydroxyproline, cystine, arginine, aspartic acid, glycine, glutamic acid, threonine, agedoite, histidine, tyrosine, tryptophan, valine, leucine, serine, isoleucine, phenylalanine, c-alanine, methionine, hypoglycin A.The compound of vitamin: VA, VB1, VB2, VB6, VC, VE, VH, nicotinic acid, folic acid, carotene, metal ion and vitamin.Organic acid: malic acid, citric acid, tartaric acid, succinic acid, cinnamic acid, fatty acid, succinic acid, lactic acid, P-coumaric acid, acetic acid, sad, the acid of capric acid, lauric acid, nonendioic acid, dodecylic acid, nutmeg pentadecanoic acid, Palmic acid, tridecanoic acid, stearic acid oleic acid, linoleic acid, arachidonic acid, magnesium lactate, calcium oxalate, 1-Hydroxy-1,2,3-propanetricarboxylic acid..Enzyme (peptide): amylase, cellulase, catalase, oxidase, lactic acid dehydrogenase, alkaline phosphatase, acid p'tase, glutamate pyruvate transaminase, glutamic oxaloacetic transaminase, GOT, Kallidin I enzyme allinase, angiotensin, lectins.
Geniposide is a kind of iridoid glucoside, soluble in water, is the main pharmacodynamics composition of Fructus Gardeniae.Geniposide all has significant curative effect to digestive system, cardiovascular system central nervous system disease of unifying, and in addition, geniposide also has the effect of certain antiinflammatory and treatment soft tissue injury.No. CAS: 24512-63-8, molecular weight: 388.37, density: 1.49g/cm3, boiling point: 622.2 DEG C, flash-point: 224 DEG C, Fructus Gardeniae derives from the dry mature fruit of Maguireothamnus speciosus Fructus Gardeniae Gardenia jasminoides Ellis.There is cathartic, analgesia, function of gallbladder promoting, antiinflammatory, treatment soft tissue injury and suppress gastric secretion and reduce the effects such as pancreatic amylase.Jasminoidin has multiple use, the fermentation of different condition, can make natural edible coloring agent gardenia blue and gardenia red, is also the material medicine being used for the treatment of the disease such as cardiovascular and cerebrovascular vessel, liver and gall and diabetes.Be a kind of iridoid glucoside, soluble in water, be the main pharmacodynamics composition of Fructus Gardeniae, content is with about the 3%-8% that do not coexist in the place of production.Geniposide can be hydrolyzed to genipin by beta-glucosidase.Modern study shows, geniposide all has significant curative effect to digestive system, cardiovascular system central nervous system disease of unifying, and in addition, geniposide also has the effect of certain antiinflammatory and treatment soft tissue injury.Geniposide, except medicinal, is also widely used in other field, as can be used as plant promoter, biological detection agent etc.
At present, the extracting method of geniposide generally adopts the organic solvent such as chloroform, dehydrated alcohol to extract in surname extraction bottle, obtain active component Fructus Gardeniae total glycosides total in Fructus Gardeniae, and then upper silicagel column is separated, with a certain proportion of methanol, chloroform mixed liquor eluting, eluent carries out recrystallization in acetone and obtains geniposide crystal, separablely in general 100g fruit of Fructus Gardeniae obtains about 4.0g geniposide.
Puerarin is yellow crystal, and water-soluble, methanol, ethanol, pyridine, be soluble in hot water, is insoluble in benzene, chloroform, ether etc., reacts displaing yellow with magnesium acetate, reacts in yellow mercury oxide with lead acetate.High-load is white, needle-shaped crystals powder, belongs to osajin.Have and improve immunity, strengthen myocardial contraction, protecting myocardial cell, reduces blood pressure, and has the effects such as antiplatelet aggregation.No. CAS: 3681-99-0, molecular formula: C21H20O9, molecular weight: 416.38, physicochemical property: yellow crystal, water-soluble, methanol, ethanol, pyridine, be soluble in hot water, be insoluble in benzene, chloroform, ether etc., react displaing yellow with magnesium acetate, react in yellow mercury oxide with lead acetate.Radix Puerariae derives from leguminous plant Pueraria lobota Pueraria lobata (Willd.) Ohwi root, Herba Gelsemii Elegantis P.thunbergiana Benth. root.Fusing point 187-189 DEG C.Low content be brown ceramic powder, high-load is white, needle-shaped crystals powder, have improve immunity, strengthen myocardial contraction, protecting myocardial cell, reduces blood pressure, and has the effects such as antiplatelet aggregation.Puerarin is on the impact of liver system: puerarin contains saponins compound, has protective effect to hepatic tissue immune impairment, C-29 position hydroxyl and C-5 " oxy radical can strengthen liver-protecting activity.Puerarin is absorbed by stomach can protect hepatic injury, induced activation apoptosis on hepatic stellate cells, effectively reverses the hepatic fibrosis of chemical induction, also has protective effect, have many-sided physiologically active simultaneously to the acute liver damage of tetrachloro-methane induction.Puerarin is on the impact of cardiovascular system: the total flavones in Radix Puerariae can increase brain and blood flow coronarius.Puerarin has obvious facilitation to the cerebral circulation of animal and human's body and peripheral circulation.Radix Puerariae total flavones improve the cerebrovascular tension force of hypertension and patients with coronary heart disease, elasticity and Pulsating quality confession because of etc. in all have gentle facilitation.Puerarin not only improves the normal brain activity microcirculation of human body, and also improves significantly to microcirculation disturbance, and main manifestations is that the amplitude of local microvascular blood flow and motion increases.The Microcirculation of Nailfold of puerarin to patients with sudden sensorineural hearing loss is also improved effect, can accelerate microvascular blood flow velocity, removes blood vessel loop congestion, improves the audition of patient.Puerarin has protective effect to hypoxic cardiac muscle, and puerarin obviously can reduce the oxygen consumption of ischemic myocardium, and cardioprotection is from the ultrastructure damage of ischemia again caused by the perfusion of port.Puerarin is the single composition flavonoid glycoside of one extracted from legume pueraria lobata root, there is blood circulation promoting and blood stasis dispelling, improve microcirculation, coronary artery dilator and the effect such as cerebrovascular, reduction myocardial oxygen consumption, its preparation puerarin injection is clinical is used for the treatment of cardiovascular and cerebrovascular disease and retinal vascular disease, retinopathy and sudden deafness etc.c
Inokopolyose is separation from Radix Achyranthis Bidentatae, extracts a kind of micromolecular polysaccharide compound obtained, and pharmacological testing shows that it has and improves body's immunity, leukocyte increasing, Tumor suppression transfer and the liver protecting function, and long-term taking is without any side effects.Inokopolyose be China's reported first there is immunocompetent micromolecular polysaccharide, compared with some known polysaccharide, it is little that Inokopolyose has molecular weight, no antigen, good water solubility, human body easily absorbs, chemical extraction steady quality, not only can be used as a kind of disease of Drug therapy immunologic hypofunction, as tumor, hepatitis etc., and can be used as a kind of immunostimulant and be developed to health product.Clinical preliminary test shows effectively to promote leukocyte, and the symptom such as simultaneously to receive to the stomach of patient, weak has clear improvement.
Above-mentioned Aloe is Aloe vera L.var. chinensis(Haw.)Berg., Classification system Aloe chinensis Berger, and geniposide, puerarin, Inokopolyose are all purchased from Xi'an and continuous heavy rain biological engineering company limited, and content is more than 98%.
Cetyl sulfophenoxy benzenesulfonic acid disodium salt, CA registration number: 65143-89-7, molecular formula is C28H42O7S2.2Na, English name: 51842 Hexadecyl (sulfophenoxy) benzenesulfonic acid, disodium salt.
Coconut oil fatty acid monoethanolamide CA registration number: 68140-00-1.
N-cocamidopropyl propyl amide-DMG inner salt, CA registration number: 86438-79-1, molecular formula is C19H38N2O3.
Hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, trade name: Emcol 4072 Coemulsifier, witco company of the U.S. produces.
Succinyl glycyrrhetinic acid disodium, cas number: 38841-48-4
Glutamic acid diacetic acid four sodium, cas number: 51981-21-6, molecular formula is C9H9NNa4O8, English name: 16896 L-Glutamic acid, N, N-bis (carboxymethyl)-, sodium salt (1:4).
Decanoyl/octanoyl glycerides, cas number: 65381-09-1, English name: 45755 Decanoyl/octanoyl-glycerides.
Glucose fatty acid phosphate, cas number: 1739-84-0.
Hydroxypropyl phosphorate starch, cas number: 53124-00-8.
Above-mentioned surfactant, antioxidant, chelating agen raw material are all purchased from Shanghai Fei Ge Chemical Co., Ltd..
Aloe facial cleaner of the present invention, foam exquisiteness is stable, and performance is gentle, and viscosity stablization is low to the zest of skin, and after special other extracts of interpolation, more can play whitening function, the feature of environmental protection is good, and result of use is good and convenient.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, in conjunction with detailed description of the invention, the present invention is further described as follows:
Needed raw material weight proportion (unit: g) in table 1 various embodiments of the present invention
2, embodiment is prepared
The preparation of Aloe extract: get fresh Aloe vera L.var. chinensis(Haw.)Berg. kind 1000g, peeling, by Aloe mesophyll homogenate, centrifugal, obtain Aloe juice, hydro-oxidation sodium adjust ph is 7.2, and spraying dry obtains Aloe extract, and spray drying condition is inlet temperature is 100 DEG C, leaving air temp is 80 DEG C, temperature of charge is 80 DEG C, and atomizing pressure is 0.2 MPa, and spray velocity is 5ml/s.
Embodiment 1: by upper table 1, gets Aloe extract, geniposide, puerarin, Inokopolyose respectively, crosses 100 mesh sieves, mix homogeneously, adding distil water, stirs 10min; Add cetyl sulfophenoxy benzenesulfonic acid disodium salt, coconut oil fatty acid monoethanolamide, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, decanoyl/octanoyl glycerides, glutamic acid diacetic acid four sodium, succinyl glycyrrhetinic acid disodium, glucose fatty acid phosphate, hydroxypropyl phosphorate starch, be uniformly mixed.
Embodiment 2: by upper table 1, gets Aloe extract, puerarin, Inokopolyose respectively, crosses 100 mesh sieves, mix homogeneously, adding distil water, stirs 10min; Add cetyl sulfophenoxy benzenesulfonic acid disodium salt, coconut oil fatty acid monoethanolamide, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, decanoyl/octanoyl glycerides, glutamic acid diacetic acid four sodium, succinyl glycyrrhetinic acid disodium, glucose fatty acid phosphate, hydroxypropyl phosphorate starch, be uniformly mixed.
Embodiment 3: by upper table 1, gets Aloe extract, geniposide, Inokopolyose respectively, crosses 100 mesh sieves, mix homogeneously, adding distil water, stirs 10min; Add cetyl sulfophenoxy benzenesulfonic acid disodium salt, coconut oil fatty acid monoethanolamide, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, decanoyl/octanoyl glycerides, glutamic acid diacetic acid four sodium, succinyl glycyrrhetinic acid disodium, glucose fatty acid phosphate, hydroxypropyl phosphorate starch, be uniformly mixed.
Embodiment 4: by upper table 1, gets Aloe extract, geniposide, puerarin respectively, crosses 100 mesh sieves, mix homogeneously, adding distil water, stirs 10min; Add cetyl sulfophenoxy benzenesulfonic acid disodium salt, coconut oil fatty acid monoethanolamide, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, decanoyl/octanoyl glycerides, glutamic acid diacetic acid four sodium, succinyl glycyrrhetinic acid disodium, glucose fatty acid phosphate, hydroxypropyl phosphorate starch, be uniformly mixed.
Embodiment 5: by upper table 1, gets Aloe extract, geniposide, puerarin, Inokopolyose respectively, crosses 100 mesh sieves, mix homogeneously, adding distil water, stirs 10min; Add cetyl sulfophenoxy benzenesulfonic acid disodium salt, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt, decanoyl/octanoyl glycerides, glutamic acid diacetic acid four sodium, succinyl glycyrrhetinic acid disodium, glucose fatty acid phosphate, hydroxypropyl phosphorate starch, be uniformly mixed.
Embodiment 6: by upper table 1, gets Aloe extract, geniposide, puerarin, Inokopolyose respectively, crosses 100 mesh sieves, mix homogeneously, adding distil water, stirs 10min; Add coconut oil fatty acid monoethanolamide, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, decanoyl/octanoyl glycerides, glutamic acid diacetic acid four sodium, succinyl glycyrrhetinic acid disodium, glucose fatty acid phosphate, hydroxypropyl phosphorate starch, be uniformly mixed.
Embodiment 7: by upper table 1, gets Aloe extract, geniposide, puerarin, Inokopolyose respectively, crosses 100 mesh sieves, mix homogeneously, adding distil water, stirs 10min; Add cetyl sulfophenoxy benzenesulfonic acid disodium salt, coconut oil fatty acid monoethanolamide, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, decanoyl/octanoyl glycerides, glutamic acid diacetic acid four sodium, glucose fatty acid phosphate, be uniformly mixed.
Embodiment 8: by upper table 1, gets Aloe extract, geniposide, puerarin, Inokopolyose respectively, crosses 100 mesh sieves, mix homogeneously, adding distil water, stirs 10min; Add cetyl sulfophenoxy benzenesulfonic acid disodium salt, coconut oil fatty acid monoethanolamide, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, decanoyl/octanoyl glycerides, succinyl glycyrrhetinic acid disodium, hydroxypropyl phosphorate starch, be uniformly mixed.
3, effect example
Test one: to the clinical research of face's chloasma, freckle, senile plaque, butterfly spot
Test method: respectively select face have chloasma, freckle, senile plaque, butterfly spot volunteer 30 example test, respectively with cleansing milk one bottle of about 150g that embodiment 1-8 is obtained, wash one's face once with the warm water of 25-45 DEG C after getting up early morning every day and before sleeping, wash one's face at every turn and fully massage face, make cleansing milk stop about 1 minute in face, repeat above operation at every turn.Its effective percentage (%) is added up after test carries out 40 days.Criterion of therapeutical effect: 1. effective: subjective symptoms has and alleviates significantly or disappear.2. effective: subjective symptoms have to a certain degree alleviate but not too obvious.3.: invalid: face's speckle still obviously or do not alleviate.Result of the test sees the following form 2:
Table 2 embodiment 1-8 is to face's speckle dispelling result of the test
Sample source |
Volunteer (example) |
Effective |
Effectively |
Invalid |
Total effective rate (%) |
Embodiment 1 |
30 |
15 |
12 |
3 |
90 |
Embodiment 2 |
30 |
11 |
13 |
6 |
80 |
Embodiment 3 |
30 |
10 |
16 |
4 |
86.7 |
Embodiment 4 |
30 |
12 |
13 |
5 |
83.3 |
Embodiment 5 |
30 |
14 |
14 |
2 |
93.3 |
Embodiment 6 |
30 |
12 |
15 |
3 |
90 |
Embodiment 7 |
30 |
10 |
18 |
2 |
93.3 |
Embodiment 8 |
30 |
10 |
17 |
3 |
90 |
Table 2 shows: embodiment 1-8 all has good effect to face's chloasma, freckle, senile plaque, butterfly spot; Wherein embodiment 1,5-8 is better than embodiment 2-4, illustrates that Aloe extract, geniposide, puerarin, Inokopolyose compatibility result of use are better.
Test two: to the clinical research of face's whitening
Test method: select face respectively, volunteer 50 example that the wing of nose has obvious blackhead tests, respectively with cleansing milk one bottle of about 150g that embodiment 1-8 is obtained, wash one's face once with the warm water of 25-45 DEG C after getting up early morning every day and before sleeping, wash one's face at every turn and fully massage face, make cleansing milk stop about 1 minute in face, repeat above operation at every turn.Its effective percentage (%) is added up after test carries out 30 days.Criterion of therapeutical effect: 1. effective: blackhead thoroughly disappears.2. effective: blackhead has desalination to a certain degree.3.: invalid: blackhead still obviously or do not alleviate.Result of the test sees the following form 3:
Table 3 embodiment 1-8 is to the result of the test of blackhead
Sample source |
Volunteer (example) |
Effective |
Effectively |
Invalid |
Total effective rate (%) |
Embodiment 1 |
30 |
12 |
18 |
0 |
100 |
Embodiment 2 |
30 |
12 |
15 |
3 |
90 |
Embodiment 3 |
30 |
14 |
13 |
3 |
90 |
Embodiment 4 |
30 |
14 |
12 |
4 |
86.7 |
Embodiment 5 |
30 |
16 |
14 |
0 |
100 |
Embodiment 6 |
30 |
18 |
10 |
2 |
93.3 |
Embodiment 7 |
30 |
10 |
19 |
1 |
96.7 |
Embodiment 8 |
30 |
14 |
16 |
0 |
100 |
Table 3 shows, and: embodiment 1-8 all has blackhead and good cleanly dispels effect; Wherein embodiment 1,5-8 is better than embodiment 2-4, illustrates that Aloe extract, geniposide, puerarin, Inokopolyose compatibility result of use are better.
Test three: on the impact of clean test, the test of gentle zest, stability test
Test method: described clean test is: will prepare embodiment 1-8, issues 50 testers respectively and uses.Tester uses during sample and cleans according to identical method, and often kind of a sample uses 2 weeks.Tester according to oneself feel mark.Standards of grading take ten point system, and 1 point the poorest, and 10 points best.
The concrete clean method of tester is: after first using clear water to drench skin, use product of the present invention in right amount in the palm of the hand, after rubbing out foam gently, is coated with and face, and gently rubs face skin one minute; Then rinse well with clear water, repeat above-mentioned steps, each sample determination 6 times, the results are shown in Table 3.
Described gentle zest test is: will prepare case study on implementation 1-8, and issue 50 testers respectively and contrast use.Often kind of a sample uses 2 weeks, tester according to oneself feel appraise through comparison.Content on probation comprises: with or without excitement, with or without pruritus, facial skin with or without general red, contact around eyes with or without general red.Evaluation criterion has been taked, slightly, nothing, test result is shown in 4.
The concrete method of testing of tester is: after first using clear water to drench skin, use product of the present invention in right amount in the palm of the hand, after rubbing out foam gently, be coated with and face and circumference of eyes, and gently rub face skin one minute, then rinse well with clear water, circumference of eyes is also skin one minute around massaging eyes gently, then rinse well with clear water, repeat above-mentioned steps, each sample test six times.(remarks: above Ocular irritation test is because of with in clear water flushing process, does not avoid eyes, the general red phenomenon of generation)
Table 4 cleansing milk result of use of the present invention evaluation table
Sample source |
Skin comfort degree |
Bath skinfeel |
Clean up sense |
Moisturizing effect after dry |
Foaming abundancy sense |
Embodiment 1 |
9 |
9.2 |
9.5 |
9.2 |
9 |
Embodiment 2 |
9.2 |
9.3 |
9 |
9.1 |
9.2 |
Embodiment 3 |
9.7 |
9.5 |
9.1 |
8.5 |
8.9 |
Embodiment 4 |
9.1 |
9.1 |
9.4 |
9.3 |
9.1 |
Embodiment 5 |
7.5 |
7.8 |
8.6 |
8.8 |
7.4 |
Embodiment 6 |
8.1 |
7.6 |
7.9 |
7.3 |
8.2 |
Embodiment 7 |
7.9 |
7.8 |
8.3 |
7.8 |
8.4 |
Embodiment 8 |
7.4 |
8.2 |
8.0 |
7.8 |
7.6 |
Table 4 shows: embodiment 1-4 skin comfort degree, bath skinfeel, clean up sense, moisturizing effect after dry, foaming abundancy sense is significantly better than embodiment 5-8, cetyl sulfophenoxy benzenesulfonic acid disodium salt is described, coconut oil fatty acid monoethanolamide, N-cocamidopropyl propyl amide-N, N-dimethylglycine inner salt, hydrogenated cotton seeds oil glyceride disodium sulfosuccinate salt, after the surfactant compounds such as decanoyl/octanoyl glycerides, chelating agen glutamic acid diacetic acid four sodium and succinyl glycyrrhetinic acid disodium composite, there is gentle non-stimulated effect, than being used alone wherein one or more surfactants or chelating agen better effects if.
Test four: on the impact of cleansing milk viscosity
Test method: viscosity measurement of the present invention uses rotor-type Rotary Viscosimeter (the NDJ-8S rotational viscometer that Shanghai Ping Xuan scientific instrument company limited produces) to measure, and select No. 4 rotors, rotating speed is 3rpm, and measuring temperature is 25 DEG C.Test sample 10ml is drawn with 10ml disposable syringe, syringe needle one end seals, vertically be fixed in the environment of 25 DEG C, supporting for NDJ-8S rotational viscometer No. 4 rotors are installed on rotational viscometer, regulate rotational viscometer in level, be dipped vertically into and fill in the 10ml syringe of test sample, the graduation mark of rotor and the liquid level of test sample maintain an equal level, and leave standstill after 10 minutes, open rotor, adjusting rotary speed is 3rpm, starts to measure.Measure the k value of 0h, 24h, 48h, 72h respectively.The results are shown in Table 5.
Effect appraise table (3 revs/min) unit: the Pa.s of table 5 cleansing milk viscosity of the present invention
Sample source |
0h |
24h |
48h |
72h |
Embodiment 1 |
14 |
13 |
15 |
14 |
Embodiment 2 |
15 |
16 |
15 |
14 |
Embodiment 3 |
14 |
13 |
16 |
13 |
Embodiment 4 |
14 |
16 |
14 |
14 |
Embodiment 5 |
13 |
15 |
15 |
13 |
Embodiment 6 |
14 |
15 |
13 |
15 |
Embodiment 7 |
16 |
15 |
13 |
10 |
Embodiment 8 |
15 |
14 |
10 |
8 |
Table 5 shows: embodiment 1-6 stability of viscidity is significantly better than embodiment 7-8, illustrate glutamic acid diacetic acid four sodium and succinyl glycyrrhetinic acid disodium composite, glucose fatty acid phosphate and hydroxypropyl phosphorate starch thickener composite after, viscosity stablization, than being used alone wherein a kind of better effects if.Above-mentioned difference technical characteristic did not have open in the prior art, was not common practise yet.