CN104248663B - A kind of buckwheat fruit mouth-keeping tablet for reliving sore-throat and preparation method thereof - Google Patents
A kind of buckwheat fruit mouth-keeping tablet for reliving sore-throat and preparation method thereof Download PDFInfo
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- CN104248663B CN104248663B CN201410468853.8A CN201410468853A CN104248663B CN 104248663 B CN104248663 B CN 104248663B CN 201410468853 A CN201410468853 A CN 201410468853A CN 104248663 B CN104248663 B CN 104248663B
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Abstract
The invention discloses a kind of buckwheat fruit mouth-keeping tablet for reliving sore-throat and preparation method thereof, this buccal tablet is made up of the raw material of following mass percent: Radix Et Rhizoma Fagopyri Tatarici Fructus Momordicae extract 19.5%～29.5%, Mentholum 0.5%, filler 69.5%～79.5% and lubricant 0.25%～0.5%, described Radix Et Rhizoma Fagopyri Tatarici Fructus Momordicae extract by tartary buckwheat extract and Fructus Momordicae extract by (1～4): the mass ratio of (3～5) is mixed prepared.Radix Et Rhizoma Fagopyri Tatarici and Fructus Momordicae compatibility are used by the present invention first, and both combinations can strengthen Radix Et Rhizoma Fagopyri Tatarici sore-throat relieving effect, the sugariness that Fructus Momordicae itself has simultaneously, make the buccal tablet of the present invention without adding sweeting agent or correctives can overcome the defect of Radix Et Rhizoma Fagopyri Tatarici bitter in the mouth, mouthfeel difference.Compared with other Radix Et Rhizoma Fagopyri Tatarici product, the buckwheat fruit mouth-keeping tablet for reliving sore-throat of the present invention is easy to carry and takes, good in taste, can be convenient for people to suck alleviation pharyngeal inflammation pharyngeal the most in good time.
Description
Technical field
The present invention relates to a kind of fruit mouth-keeping tablet for reliving sore-throat of the buckwheat with tartary buckwheat extract and Fructus Momordicae extract as raw material
And preparation method thereof.
Background technology
Buccal tablet is to be contained in oral cavity the compressed tablet slowly dissolved, can be lasting to oral cavity and pharyngeal generation
Drug effect, for antiinflammatory locally, sterilization etc..Buccal tablet is because of its excellent mouthfeel and the side of taking easily
Method and welcome by extensive patients.
To have the advantage that (1) acts directly on pharyngeal for buccal tablet treatment pharyngitis, have antibacterial, kill
Bacterium, antiinflammatory, detumescence, desaturation thick secretions etc. act on；(2) owing to slowly containing changing, making medicine energy
Long period rests on pharyngeal, persistently plays drug effect；(3) for alleviating the sense of discomfort such as dry pharynx, pharyngalgia
Feel instant effect.
Radix Et Rhizoma Fagopyri Tatarici is one of medicine food dual purpose plant, the main isoreactivity composition Han bioflavonoid, modern study
Show that it has antiinflammatory sore-throat relieving, reduces blood fat, prevents and treats the multiple curative effects such as diabetes.Though Radix Et Rhizoma Fagopyri Tatarici has well
Health-care effect, if but be directly prepared into buccal tablet, its bitterness having make it difficult for consumer accept.Sieve
The distinctive precious cucurbitaceous plant of Han Guoshi China, have the title of the good fruit of good medicine, can removing heat from the lung and relieving sorethroat, change
Phlegm and relieving cough, cures mainly phlegm-fire cough, laryngopharynx swelling and pain.Meanwhile, modern pharmacy research finds, Fructus Momordicae contains
Having abundant mogroside, the sugariness of this sweet glycosides is 300 times of sweetness of cane sugar, therefore by arhat
Fruit and Radix Et Rhizoma Fagopyri Tatarici compatibility use, and not only can strengthen antiinflammatory sore-throat relieving effect, also can effectively alleviate Radix Et Rhizoma Fagopyri Tatarici when eating
Bitterness.
There are no at present and prepare the relevant report of buccal tablet with Radix Et Rhizoma Fagopyri Tatarici and Fructus Momordicae for raw material.
Summary of the invention
It is an object of the invention to provide one and can strengthen Radix Et Rhizoma Fagopyri Tatarici sore-throat relieving effect, can effectively reduce again hardship
Buckwheat fruit mouth-keeping tablet for reliving sore-throat of buckwheat bitterness and preparation method thereof.
For reaching above-mentioned purpose, buckwheat fruit former by following mass percent of mouth-keeping tablet for reliving sore-throat that the present invention provides
Material is made:
Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract 19.5%～29.5%, Mentholum 0.5%, filler 69.5%～
79.5% and lubricant 0.25%～0.5%, described Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract by tartary buckwheat extract and
Fructus Momordicae extract presses (1～4): the mass ratio of (3～5) is mixed prepared.
Further, tartary buckwheat extract is prepared by following methods: take the dry seed of Radix Et Rhizoma Fagopyri Tatarici, add 60～
The ethanol extraction of 75% 2 times, each 60min, filters extracting solution, collects filtrate, by filtrate decompression
It is spray-dried after concentration, i.e. prepares tartary buckwheat extract；Fructus Momordicae extract is prepared by following methods: take
Fructus Momordicae, extracting in water 2 times after being crushed, each 60～90min, filter extracting solution, collect
Filtrate, by being spray-dried after filtrate reduced in volume, i.e. prepares Fructus Momordicae extract.
Further, the one during filler is selected from lactose, mannitol, sucrose, sorbitol or one
Above.
Further, lubricant is selected from magnesium stearate or micropowder silica gel.
The preparation method of the buckwheat fruit mouth-keeping tablet for reliving sore-throat that the present invention provides comprises the steps:
(1) Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract is crossed 100～120 mesh sieves, by filler and lubricant difference
120 mesh sieves are crossed after pulverizing；
(2) by after Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract and filler mix homogeneously, pelletize and be dried；
(3), after Mentholum being dissolved, uniformly it is sprayed on the granule that step (2) prepares, airtight placement
After 10-16 hour, add lubricant and fully mix；
(4) tabletting, obtains buckwheat fruit mouth-keeping tablet for reliving sore-throat.
Further, tartary buckwheat extract is prepared by following methods: take the dry seed of Radix Et Rhizoma Fagopyri Tatarici, add 60%～
The ethanol extraction of 75% 2 times, each 60min, filters extracting solution, collects filtrate, filtrate subtracted
Pressure is spray-dried after concentrating, and i.e. prepares tartary buckwheat extract；Fructus Momordicae extract is prepared by following methods:
Take Fructus Momordicae, extracting in water 2 times after being crushed, each 60～90min, extracting solution is filtered,
Collect filtrate, by being spray-dried after filtrate reduced in volume, i.e. prepare Fructus Momordicae extract.
Further, the one during filler is selected from lactose, mannitol, sucrose, sorbitol or one
Above.
Further, lubricant is selected from magnesium stearate or micropowder silica gel.
Radix Et Rhizoma Fagopyri Tatarici and Fructus Momordicae compatibility are used by the present invention first, and both combinations both can strengthen Radix Et Rhizoma Fagopyri Tatarici sore-throat relieving merit
Effect, the sugariness that Fructus Momordicae itself has simultaneously, make again buccal tablet in the preparation without add sweeting agent or
Correctives can overcome the defect of Radix Et Rhizoma Fagopyri Tatarici bitter in the mouth, mouthfeel difference.Compared with other Radix Et Rhizoma Fagopyri Tatarici product, the present invention
Buckwheat fruit mouth-keeping tablet for reliving sore-throat be easy to carry and take, good in taste, pharyngeal discomfort can be alleviated in being contained in mouth.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further details, but present disclosure not only limiting
In this.
Embodiment 1
Composition of raw materials:
Preparation method:
(1) preparation of Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract
The preparation of tartary buckwheat extract: take the dry seed of Radix Et Rhizoma Fagopyri Tatarici, adds the ethanol extraction 2 times of 75%,
60min every time, filters extracting solution, collects filtrate, will be spray-dried, receive after filtrate reduced in volume
Collection powdered extract powder, obtains tartary buckwheat extract；
The preparation of Fructus Momordicae extract: take Fructus Momordicae, extracting in water 2 times after being crushed, each 60
Min, filters extracting solution, collects filtrate, will be spray-dried, collect and be dried leaching after filtrate reduced in volume
Cream powder, obtains Fructus Momordicae extract；
Above-mentioned tartary buckwheat extract and Fructus Momordicae extract are mixed by the mass ratio of 1:5, i.e. prepare Radix Et Rhizoma Fagopyri Tatarici-
Fructus Momordicae extract；
(2) Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract is crossed 100～120 mesh sieves, by mannitol, sorbitol and breast
Cross 120 mesh sieves after Icing Sugar is broken, cross 120 mesh sieves after magnesium stearate being pulverized, exsiccator saves backup；
(3) by after Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract and mannitol, sorbitol and lactose mix homogeneously, with suitable
Amount alcohol granulation is also dried；
(4), after Mentholum being dissolved by ethanol in proper amount, uniformly it is sprayed on the granule that step (3) prepares,
After airtight placement 12 hours, add magnesium stearate and fully mix；
(5) tabletting, is made as 1000, obtained buckwheat fruit mouth-keeping tablet for reliving sore-throat any surface finish, exquisiteness, in
Fallow.
Embodiment 2
Composition of raw materials:
Preparation method:
(1) preparation of Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract
The preparation of tartary buckwheat extract: take the dry seed of Radix Et Rhizoma Fagopyri Tatarici, adds the ethanol extraction 2 times of 60%,
60min every time, filters extracting solution, collects filtrate, will be spray-dried, receive after filtrate reduced in volume
Collection powdered extract powder, obtains tartary buckwheat extract；
The preparation of Fructus Momordicae extract: take Fructus Momordicae, extracting in water 2 times after being crushed, each 90
Min, filters extracting solution, collects filtrate, will be spray-dried, collect and be dried leaching after filtrate reduced in volume
Cream powder, obtains Fructus Momordicae extract；
Above-mentioned tartary buckwheat extract and Fructus Momordicae extract are mixed by the mass ratio of 4:3, i.e. prepare Radix Et Rhizoma Fagopyri Tatarici-
Fructus Momordicae extract；
(2) Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract is crossed 100～120 mesh sieves, by mannitol, lactose and sucrose
Cross 120 mesh sieves after pulverizing, cross 120 mesh sieves after micropowder silica gel being pulverized, exsiccator saves backup；
(3) by after Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract and mannitol, lactose and sucrose mix homogeneously, with appropriate
Alcohol granulation is also dried；
(4), after Mentholum being dissolved by ethanol in proper amount, uniformly it is sprayed on the granule that step (3) prepares,
After airtight placement 16 hours, add micropowder silica gel and fully mix；
(5) tabletting, is made as 1000, obtained buckwheat fruit mouth-keeping tablet for reliving sore-throat any surface finish, exquisiteness,
In yellowish-brown.
Claims (6)
1. a buckwheat fruit mouth-keeping tablet for reliving sore-throat, it is characterised in that be made up of the raw material of following mass percent:
Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract 19.5%～29.5%, Mentholum 0.5%, filler 69.5%～79.5% and lubricant
0.25%～0.5%, described Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract is pressed (1～4) by tartary buckwheat extract and Fructus Momordicae extract: (3～5)
Mass ratio be mixed and make；
Described tartary buckwheat extract is prepared by following methods: take the dry seed of Radix Et Rhizoma Fagopyri Tatarici, adds the ethanol extraction 2 times of 60～75%,
60min every time, filters extracting solution, collects filtrate, by being spray-dried after filtrate reduced in volume, i.e. prepares tartary buckwheat extract；
Described Fructus Momordicae extract is prepared by following methods: take Fructus Momordicae, extracting in water 2 times after being crushed, each 60～
90min, filters extracting solution, collects filtrate, by being spray-dried after filtrate reduced in volume, i.e. prepares Fructus Momordicae extract.
Buckwheat the most according to claim 1 fruit mouth-keeping tablet for reliving sore-throat, it is characterised in that: described filler is selected from lactose, mannitol, sugarcane
Sugar, one or more in sorbitol.
Buckwheat the most according to claim 1 fruit mouth-keeping tablet for reliving sore-throat, it is characterised in that: described lubricant is selected from magnesium stearate or micropowder
Silica gel.
4. the preparation method of a buckwheat as claimed in claim 1 fruit mouth-keeping tablet for reliving sore-throat, it is characterised in that comprise the steps:
(1) Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract is crossed 100～120 mesh sieves, after filler and lubricant being pulverized respectively, cross 120 mesh sieves；
(2), after Radix Et Rhizoma Fagopyri Tatarici-Fructus Momordicae extract being mixed homogeneously with filler, pelletize and be dried；
(3) after Mentholum being dissolved, uniformly it is sprayed on the granule that step (2) prepares, airtight places after 10-16 hour, add
Lubricant also fully mixes；
(4) tabletting, obtains buckwheat fruit mouth-keeping tablet for reliving sore-throat.
The preparation method of buckwheat the most according to claim 4 fruit mouth-keeping tablet for reliving sore-throat, it is characterised in that: described filler is selected from breast
One or more in sugar, mannitol, sucrose, sorbitol.
The preparation method of buckwheat the most according to claim 4 fruit mouth-keeping tablet for reliving sore-throat, it is characterised in that: described lubricant is selected from tristearin
Acid magnesium or micropowder silica gel.
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| CN201410468853.8A CN104248663B (en) | 2014-09-15 | 2014-09-15 | A kind of buckwheat fruit mouth-keeping tablet for reliving sore-throat and preparation method thereof |
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| CN201410468853.8A CN104248663B (en) | 2014-09-15 | 2014-09-15 | A kind of buckwheat fruit mouth-keeping tablet for reliving sore-throat and preparation method thereof |
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| CN104248663B true CN104248663B (en) | 2016-08-24 |
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Families Citing this family (3)
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| CN104771632A (en) * | 2015-04-09 | 2015-07-15 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicinal oral liquid for treating hoarseness and preparation method of oral liquid |
| CN105192235A (en) * | 2015-11-05 | 2015-12-30 | 广西壮族自治区药用植物园 | Siraitia grosvenorii peppermint candy and preparation method thereof |
| CN105767436A (en) * | 2016-05-20 | 2016-07-20 | 成都大学 | Health chewing gums and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101878898A (en) * | 2009-05-07 | 2010-11-10 | 湖南人文科技学院 | Compound polygonatum buccal tablet and preparation method thereof |
| CN102524881A (en) * | 2010-12-29 | 2012-07-04 | 郭宇 | Blended beverage of Tartary buckwheat and Momordica grosvenori |
| CN103652181A (en) * | 2013-12-04 | 2014-03-26 | 曾玉 | A tartary buckwheat tea beverage |
-
2014
- 2014-09-15 CN CN201410468853.8A patent/CN104248663B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101878898A (en) * | 2009-05-07 | 2010-11-10 | 湖南人文科技学院 | Compound polygonatum buccal tablet and preparation method thereof |
| CN102524881A (en) * | 2010-12-29 | 2012-07-04 | 郭宇 | Blended beverage of Tartary buckwheat and Momordica grosvenori |
| CN103652181A (en) * | 2013-12-04 | 2014-03-26 | 曾玉 | A tartary buckwheat tea beverage |
Non-Patent Citations (1)
| Title |
|---|
| 罗汉果的临床应用;李今玉等;《现代医药卫生》;20111231;第27卷(第21期);3286-3287 * |
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Effective date of registration: 20171122 Address after: 610000 Sichuan province Chengdu Shuangliu Industrial Zone Southwest Airport Economic Development Zone concentrated area Patentee after: Sichuan ring too Biotechnology Co., Ltd. Address before: 610106 Sichuan province Chengdu City Shiling Town East Patentee before: Chengdu University |
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Address after: 610000 Airport No.979, Southwest Airport Economic Development Zone, Shuangliu District, Chengdu City, Sichuan Province Patentee after: Sichuan Huantai biological Polytron Technologies Inc Address before: Industrial Concentration Zone of Southwest Airport Economic Development Zone, Shuangliu District, Chengdu Patentee before: Sichuan ring too Biotechnology Co., Ltd. |
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Address after: 610000 Airport No.979, Southwest Airport Economic Development Zone, Shuangliu District, Chengdu City, Sichuan Province Patentee after: Huantai Biotechnology Co., Ltd Address before: 610000 Airport No.979, Southwest Airport Economic Development Zone, Shuangliu District, Chengdu City, Sichuan Province Patentee before: Sichuan Huantai biological Polytron Technologies Inc |