CN104244975A - 用于制备树突细胞疫苗的方法 - Google Patents

用于制备树突细胞疫苗的方法 Download PDF

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Publication number
CN104244975A
CN104244975A CN201380020366.9A CN201380020366A CN104244975A CN 104244975 A CN104244975 A CN 104244975A CN 201380020366 A CN201380020366 A CN 201380020366A CN 104244975 A CN104244975 A CN 104244975A
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hiv
cells
dendritic cell
cell
antigen
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CN201380020366.9A
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Chinese (zh)
Inventor
费莉佩·加西亚阿尔凯德
特里萨·加拉特
努里亚·克利门特维达尔
克里斯蒂娜·吉尔罗达
约瑟夫·马里亚·加特利阿蒂加斯
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IrsiCaixa Institut de Recerca de la Sida
Esteve Pharmaceuticals SA
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IrsiCaixa Institut de Recerca de la Sida
Laboratorios del Dr Esteve SA
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Publication of CN104244975A publication Critical patent/CN104244975A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/19—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Wood Science & Technology (AREA)
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  • Hematology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201380020366.9A 2012-03-02 2013-03-01 用于制备树突细胞疫苗的方法 Pending CN104244975A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12382078 2012-03-02
EP12382078.9 2012-03-02
PCT/EP2013/054121 WO2013127976A1 (en) 2012-03-02 2013-03-01 Method for the preparation of dendritic cell vaccines

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Publication Number Publication Date
CN104244975A true CN104244975A (zh) 2014-12-24

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CN201380020366.9A Pending CN104244975A (zh) 2012-03-02 2013-03-01 用于制备树突细胞疫苗的方法

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US (1) US20150125489A1 (enExample)
EP (1) EP2819696A1 (enExample)
JP (1) JP2015513401A (enExample)
CN (1) CN104244975A (enExample)
CA (1) CA2865952A1 (enExample)
HK (1) HK1204275A1 (enExample)
IN (1) IN2014DN07961A (enExample)
MX (1) MX2014010482A (enExample)
WO (1) WO2013127976A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105039256A (zh) * 2015-07-13 2015-11-11 中政道和（北京）生物科技有限公司 一种支气管镜下获取肿瘤组织进行树突细胞培养扩增方法
CN112029724A (zh) * 2020-09-17 2020-12-04 和泓尚医(成都)生物科技有限公司 一种加速树突状细胞成熟的体外培养方法及其应用
CN113980901A (zh) * 2021-12-28 2022-01-28 上海惠盾因泰生物科技有限公司 一种制备高纯度的成熟人树突状细胞的方法及应用
CN114377122A (zh) * 2022-01-18 2022-04-22 四川大学 一种基于四面体框架核酸的复合佐剂、mRNA疫苗及其制备方法和用途

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3018819A1 (fr) * 2014-03-19 2015-09-25 Univ Bourgogne Traitement de la reponse inflammatoire et dysimmunitaire
CN103948917A (zh) * 2014-04-02 2014-07-30 江苏和泽生物科技有限公司 树突状细胞疫苗的制备方法
US11254914B2 (en) * 2015-03-12 2022-02-22 Health Research, Inc. Enrichment of CD16+ monocytes to improve dendritic cell vaccine quality
MX2018003757A (es) * 2015-09-26 2018-09-21 Primevax Immuno Oncology Inc Composiciones y metodos para producir celulas dendriticas.
JP2018007599A (ja) * 2016-07-12 2018-01-18 株式会社ガイアバイオメディシン 樹状細胞集団の調製方法
JP2020500847A (ja) 2016-11-16 2020-01-16 プライムヴァックス イミュノ−オンコロジー，インク． 癌の処置のための併用免疫療法
EP3565567A4 (en) 2017-01-04 2020-07-29 Primevax Immuno-Oncology, Inc. COMPOSITIONS AND METHODS OF THERAPY WITH DENGUE VIRUS
CN113679830B (zh) * 2021-08-27 2023-10-27 苏州大学 用于肿瘤治疗的复合纳米疫苗及其制备方法
US20250368957A1 (en) * 2022-06-24 2025-12-04 Lihpao Life Science Corp. Method for producing mature dendritic cells

Citations (2)

* Cited by examiner, † Cited by third party
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CN1489630A (zh) * 2001-01-08 2004-04-14 Hiv样颗粒及其用途
CN101056977A (zh) * 2004-10-04 2007-10-17 拜欧瓦克西姆有限公司 用于治疗hiv感染患者的亚型匹配的灭活全病毒疫苗

Family Cites Families (2)

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US5017691A (en) 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
EP1840206A1 (en) * 2006-03-28 2007-10-03 Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh Compositions for the preparation of mature dendritic cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1489630A (zh) * 2001-01-08 2004-04-14 Hiv样颗粒及其用途
CN101056977A (zh) * 2004-10-04 2007-10-17 拜欧瓦克西姆有限公司 用于治疗hiv感染患者的亚型匹配的灭活全病毒疫苗

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ABDOLAMIR LANDI ET AL: "Dendritic cells matured by a prostaglandin E2-containing cocktail can produce high levels of IL-12p70 and are more mature and Th1-biased than dendritic cells treated with TNF-αor LPS", 《IMMUNOBIOLOGY》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105039256A (zh) * 2015-07-13 2015-11-11 中政道和（北京）生物科技有限公司 一种支气管镜下获取肿瘤组织进行树突细胞培养扩增方法
CN112029724A (zh) * 2020-09-17 2020-12-04 和泓尚医(成都)生物科技有限公司 一种加速树突状细胞成熟的体外培养方法及其应用
CN113980901A (zh) * 2021-12-28 2022-01-28 上海惠盾因泰生物科技有限公司 一种制备高纯度的成熟人树突状细胞的方法及应用
CN113980901B (zh) * 2021-12-28 2022-06-17 上海惠盾因泰生物科技有限公司 一种制备高纯度的成熟人树突状细胞的方法及应用
CN114377122A (zh) * 2022-01-18 2022-04-22 四川大学 一种基于四面体框架核酸的复合佐剂、mRNA疫苗及其制备方法和用途
CN114377122B (zh) * 2022-01-18 2023-04-07 四川大学 一种基于四面体框架核酸的复合佐剂、mRNA疫苗及其制备方法和用途

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EP2819696A1 (en) 2015-01-07
JP2015513401A (ja) 2015-05-14
IN2014DN07961A (enExample) 2015-05-01
MX2014010482A (es) 2015-04-08
US20150125489A1 (en) 2015-05-07
CA2865952A1 (en) 2013-09-06
WO2013127976A1 (en) 2013-09-06
HK1204275A1 (en) 2015-11-13

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