CN104237524A - 一种酶催化的n端标记的定量蛋白质组学方法 - Google Patents
一种酶催化的n端标记的定量蛋白质组学方法 Download PDFInfo
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- CN104237524A CN104237524A CN201310245375.XA CN201310245375A CN104237524A CN 104237524 A CN104237524 A CN 104237524A CN 201310245375 A CN201310245375 A CN 201310245375A CN 104237524 A CN104237524 A CN 104237524A
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
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- Hematology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106645437A (zh) * | 2015-10-30 | 2017-05-10 | 中国科学院大连化学物理研究所 | 基于化学修饰和同位素标记多肽氨基酸序列从头测序方法 |
CN108508125A (zh) * | 2017-02-24 | 2018-09-07 | 中国科学院大连化学物理研究所 | 一种活性蛋白质与小分子相互作用的质谱检测方法 |
CN112505328A (zh) * | 2020-11-02 | 2021-03-16 | 武汉金开瑞生物工程有限公司 | 一种同位素标记试剂盒和标记方法 |
CN113774074A (zh) * | 2020-06-05 | 2021-12-10 | 复旦大学 | 一种基于肽段的靶向蛋白质组精确定量方法 |
Citations (5)
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WO2004024751A1 (de) * | 2002-08-30 | 2004-03-25 | F. Hoffmann-La Roche Ag | Verfahren zur synthese und selektiven biokatalytischen modifizierung von peptiden, peptidmimetika und proteinen |
WO2005057221A1 (en) * | 2003-12-08 | 2005-06-23 | Oxford Gene Technology Ip Limited | Mass spectrometry of arginine-containing peptides |
CN101173926A (zh) * | 2006-11-03 | 2008-05-07 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 稳定同位素18o标记蛋白质组双重定量方法与试剂盒 |
CN101782581A (zh) * | 2002-10-03 | 2010-07-21 | 诺曼·利·安德森 | 用质谱法高灵敏度定量肽 |
CN102174025A (zh) * | 2011-01-18 | 2011-09-07 | 中国科学院上海有机化学研究所 | 一种同位素标记试剂及其制备方法和应用 |
-
2013
- 2013-06-19 CN CN201310245375.XA patent/CN104237524B/zh not_active Expired - Fee Related
Patent Citations (5)
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WO2004024751A1 (de) * | 2002-08-30 | 2004-03-25 | F. Hoffmann-La Roche Ag | Verfahren zur synthese und selektiven biokatalytischen modifizierung von peptiden, peptidmimetika und proteinen |
CN101782581A (zh) * | 2002-10-03 | 2010-07-21 | 诺曼·利·安德森 | 用质谱法高灵敏度定量肽 |
WO2005057221A1 (en) * | 2003-12-08 | 2005-06-23 | Oxford Gene Technology Ip Limited | Mass spectrometry of arginine-containing peptides |
CN101173926A (zh) * | 2006-11-03 | 2008-05-07 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 稳定同位素18o标记蛋白质组双重定量方法与试剂盒 |
CN102174025A (zh) * | 2011-01-18 | 2011-09-07 | 中国科学院上海有机化学研究所 | 一种同位素标记试剂及其制备方法和应用 |
Non-Patent Citations (3)
Title |
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FRANK BORDUSA: "Proteases in Organic Synthesis", 《CHEMICAL REVIEWS》 * |
JOSIP BLONDER 等: "Combined Chemical and Enzymatic Stable Isotope Labeling for Quantitative Profiling of Detergent-Insoluble Membrane Proteins Isolated Using Triton X-100 and Brij-96", 《JOURNAL OF PROTEOME RESEARCH》 * |
YANBO PAN 等: "N-Terminal Labeling of Peptides by Trypsin-Catalyzed Ligation for Quantitative Proteomics", 《ANGEWANDTE CHEMIE INTERNATIONAL EDITION》 * |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106645437A (zh) * | 2015-10-30 | 2017-05-10 | 中国科学院大连化学物理研究所 | 基于化学修饰和同位素标记多肽氨基酸序列从头测序方法 |
CN106645437B (zh) * | 2015-10-30 | 2019-06-11 | 中国科学院大连化学物理研究所 | 基于化学修饰和同位素标记多肽氨基酸序列从头测序方法 |
CN108508125A (zh) * | 2017-02-24 | 2018-09-07 | 中国科学院大连化学物理研究所 | 一种活性蛋白质与小分子相互作用的质谱检测方法 |
CN108508125B (zh) * | 2017-02-24 | 2021-06-11 | 中国科学院大连化学物理研究所 | 一种活性蛋白质与小分子相互作用的质谱检测方法 |
CN113774074A (zh) * | 2020-06-05 | 2021-12-10 | 复旦大学 | 一种基于肽段的靶向蛋白质组精确定量方法 |
CN112505328A (zh) * | 2020-11-02 | 2021-03-16 | 武汉金开瑞生物工程有限公司 | 一种同位素标记试剂盒和标记方法 |
CN112505328B (zh) * | 2020-11-02 | 2024-02-13 | 武汉金开瑞生物工程有限公司 | 一种同位素标记试剂盒和标记方法 |
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