CN104225503A - Maca compound traditional Chinese herb preparation and preparation method thereof - Google Patents

Maca compound traditional Chinese herb preparation and preparation method thereof Download PDF

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CN104225503A
CN104225503A CN201410530795.7A CN201410530795A CN104225503A CN 104225503 A CN104225503 A CN 104225503A CN 201410530795 A CN201410530795 A CN 201410530795A CN 104225503 A CN104225503 A CN 104225503A
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maca
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semen cassiae
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钱莉秋
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Abstract

The invention discloses a maca compound traditional Chinese herb preparation. The maca compound traditional Chinese herb preparation is composed, by weight, of 50-60 parts of maca powder, 10-20 parts of pueraria, 20-30 parts of gastrodia elata, 45-55 parts of turmeric powder, 20-30 parts of semen cassiae and 5-15 parts of ginkgo biloba. The invention further discloses a preparation method of the maca compound traditional Chinese herba preparation. Maca, semen cassiae and other herbs are extracted respectively in a preparation process and different extraction methods are used according to different herb properties, so that active ingredients can be fully extracted. According to the maca compound traditional Chinese herb preparation prepared through the preparation method, various ingredients are complementary for one another, a synergistic effect is obtained, and a significant effect on blood pressure and lipid reducing can be obtained.

Description

A kind of Maca composite Chinese medicine preparation and preparation method thereof
 
Technical field
The present invention relates to a kind of health product Maca composite preparation and preparation method thereof, belong to medicine, health product and manufacture field.
Background technology
Conventionally Lepidinm meyenii Walp is except being rich in nutrition, a kind of aphrodisiac especially, its energy enhancement ability, also can strengthen fertility, Lepidinm meyenii Walp is also declared can be applicable to the treatment of the diseases such as rheumatism, respiratory disorder, depression, anemia, osteoporosis, cancer, female climacteric syndrome simultaneously.The local resident of long-term edible Lepidinm meyenii Walp is in vigorous health, strong to the withstand force of disease.
Alkaloid component tool in Lepidinm meyenii Walp is antibacterial, antiviral, anticoagulant, analgesia, anti-inflammatory, the effect such as antitumor and anti-cardiovascular disease, thus can be used for immunologic function degression, climacteric syndrome, hysteromyoma, cyclomastopathy, chronic cardiovascular and cerebrovascular disease etc.Along with the development of science, the various factors such as environmental pollution is serious, rhythm of life is fast, energy overdraw, operating pressure is large, bad life habits, physical exercise reduce increasingly make modern society sub-health state crowd ubiquity.The nutritional labeling of Lepidinm meyenii Walp general equilibrium and exclusive vigor material, can effective firm immune system, improves sub-health state.
People's results of study such as the Manuel Sandoval at U.S.'s AIbany medical university cardiovascular research center prove, maca polysaccharide has significant antioxidation, and sufficient proof Lepidinm meyenii Walp has scavenging free radicals, and Cell protection is from the effect of oxidation.Clinical experiment shows, after hyperlipemic patients takes Lepidinm meyenii Walp a period of time, Blood Cholesterol, low density lipoprotein, LDL (LDL) and triglyceride and matched group contrast, be decreased significantly (p<0.005), this is because polyunsaturated fatty acid, linoleic acid plus linolenic acid content higher (reaching 18.5% and 8.87% respectively) in Lepidinm meyenii Walp.Linoleic acid is combined into ester with cholesterol in vivo, is easy to by cholesterol transport to extravascular tissue, reduces the deposition of Ink vessel transfusing cholesterol, and impels cholesterol be converted into bile acid and discharge.Visible Lepidinm meyenii Walp has certain effect to treatment hyperlipidemia.
Increasing Lepidinm meyenii Walp product from the U.S., Peru, mouth this etc. state release one after another, product function based on strengthen energy, improvement function and alleviate female dimacteric syndrome, Lepidinm meyenii Walp complete by traditional food to " health food " and transformation.And the form of Lepidinm meyenii Walp product also by early stage MAKA dry powder, Maca wine, Maca beverage etc. to second filial generation Lepidinm meyenii Walp production developments such as Maca capsule, Lepidinm meyenii Walp tablet, Lepidinm meyenii Walp concentrated oral liquid, Maca composite health product, Lepidinm meyenii Walp becomes rapidly a nova in international Medicines and Health Product market, is subject to consumers in general's especially mid-aged population, athletes, bodybuilders, extensively the liking of female patient of climacteric syndrome.Make Maca capsule, Lepidinm meyenii Walp tablet etc. after conventional product great majority Lepidinm meyenii Walp root beats powder, its effect is difficult to fully play.And hypertension is used for the treatment of for Lepidinm meyenii Walp complex, the application of hyperlipidemia also studies less.
Theory of Chinese medical science is thought: plant amedica belongs to the product of mercilessness, although the effective ingredient such as nutrient, trace element, aminoacid contained by Lepidinm meyenii Walp enrich, also still belongs to the product of mercilessness; Therefore Lepidinm meyenii Walp needs one " in love product " fundamentally to reach the complementary compounding ingredient with having complementary action of effect, activates the vigor of the product of mercilessness, thus makes it to reach more scientific and reasonable remarkable result.Namely most Lepidinm meyenii Walp product structurally lacks the scientific compatibility in pharmacology, mechanism and the reasonably combined property between nutrient.All of these factors taken together constrains the performance of Lepidinm meyenii Walp drug effect.
Summary of the invention
The technical problem that the present invention mainly solves is to provide a kind of Maca composite Chinese medicine preparation and preparation method thereof, can utilize the principle of effect complementation between medicine, reach the effect of mutual tonification, thus effectively play the effect of blood pressure lowering, blood fat reducing.
For solving the problems of the technologies described above, the technical scheme that the present invention adopts is:
A kind of Maca composite Chinese medicine preparation is be grouped into by the one-tenth of following weight portion: pueraria root powder 50 ~ 60 parts, Radix Puerariae 10 ~ 20 parts, 20 ~ 30 parts, Rhizoma Gastrodiae, curcuma powder 45 ~ 55 parts, Semen Cassiae 20 ~ 30 parts, Folium Ginkgo 5 ~ 15 parts.
Above-mentioned Maca composite Chinese medicine preparation preferably, is be grouped into by the one-tenth of following weight portion: pueraria root powder 55 parts, Radix Puerariae 15 parts, 25 parts, Rhizoma Gastrodiae, curcuma powder 50 parts, Semen Cassiae 25 parts, Folium Ginkgo 10 parts.
The preparation method of above-mentioned Maca composite Chinese medicine preparation, comprises the steps:
(1) preparation of Maca extract:
1. dried by fresh Lepidinm meyenii Walp, dry under 35 ~ 45 DEG C of conditions, be ground into 60-120 object fine powder, add water boiling and extraction 1-2 time of 5-15 times amount, each 1-4 hour, filter, when making filtrate be concentrated into 20 DEG C, relative density is 1.1 ~ 1.3, dry;
2. by step 1. dry thing 75 ~ 85% alcoholic solution of gained extract under the condition of reflow treatment or the condition of ultrasonic Treatment, filtration, after making the mode drying of filtrate concentrating, spray-dried or drying under reduced pressure and get final product;
(2) preparation of Radix Puerariae, Rhizoma Gastrodiae, Semen Cassiae, Folium Ginkgo extract:
First take Radix Puerariae, Rhizoma Gastrodiae, Folium Ginkgo make coarse powder respectively, with volume fraction 80-90% ethanol lixiviate 2 ~ 3 times, each lixiviate ethanol used be the 4-8 of raw material gross weight doubly, each extraction time is 15-20h, and each extraction temperature is 40-60 DEG C; Medicinal residues decoct with water secondary, first time 1-3 hour, and second time 2-4 hour, filters to get filtrate after collecting decoction and each lixiviate, be evaporated in concentrate alcohol-free at 55-65 DEG C;
(3) preparation of Semen Cassiae extract:
Semen Cassiae powder is broken into 80 ~ 100 object fine powders, adds in 50-55 ° of Chinese liquor of 4-5 times of weight, at 20-35 DEG C of dipping 30-64 hour, obtain impregnation liquid; Filtered by impregnation liquid, impregnation liquid is heated to 55-60 DEG C to carry out carrying alcohol, when the proportion to extracting solution is more than 0.92 Baume, stops carrying alcohol;
(4) above-mentioned each material is carried out dehydration at 70-80 DEG C and concentrate to obtain concentrate.
Described step (1) 2. in hyperacoustic ultrasonic power be 350-400W/cm 2, extraction time 20-40 minute; Filtrate is concentrated is vacuum concentration at the temperature of 60 ~ 70 DEG C, and its vacuum is-0.050 ± 0.01Mpa.
The primary efficacy of various composition is as follows:
1, Lepidinm meyenii Walp major function and effect: improvement function, improves fertility; Firm immune system, improves sub-health state; Antioxidation, blood fat reducing, prevent arteriosclerosis; Firm immune system, improves sub-health state; Enhance metabolism, hepatoprotective; Blood nourishing and calcium replenishing; Strengthen the motor capacity of muscle.
2, Radix Puerariae major function and effect: improve hepatocellular regeneration capacity, recovers normal liver function, promotes bile secretion, prevents fat from piling up at liver; Enhance metabolism, strengthen liver detoxification function, prevent ethanol to the damage of liver; To the coronary atherosclerosis that hyperlipidemia is formed, by improving myocardial ischemia, cardiovascular disease such as control coronary heart diseases and angina pectoris, myocardial infarction etc.; To the cerebral arteriosclerosis that hyperlipidemia is formed, by improving cerebral ischemic condition, the cerebrovascular disease such as control cerebral infarction, hemiplegia, vascular dementia; Strengthening liver and gall cell autoimmunity function, opposing poisoning intrusion; Blood sugar lowering, has the effect of the aspects such as slow down aging, adjusting blood lipid blood glucose, promotion hemopoietic function, and is applied to clinical.
3, Rhizoma Gastrodiae major function and effect: can aid yang qi, mend five kinds of strain and seven kinds of impairment, promoting blood circulation, has one's ideas straightened out, its rhizome be used as medicine to have a dizzy spell in order to treatment, the disease such as numb limbs and tense tendons, infantile convulsion.
4, curcuma powder major function and effect: curcuma powder has removing blood stasis circulation of qi promoting, effect of inducing menstruation to relieve menalgia.Can be used for the blood block up stagnation of QI, the twinge of the breast side of body, amenorrhea stomachache, treating swelling and pain by traumatic injury, rheumatalgia.
5, Semen Cassiae major function and effect: bitter in the mouth, sweet and cool in nature, has the functions such as clearing away liver-fire, wind-damp dispelling, tonifying kidney and improving eyesight, is applicable to hypertension, hyperlipemia, constipation, blurred vision symptom.
6, Folium Ginkgo major function and effect: cholesterol levels in blood of human body can be effectively reduced, prevent arteriosclerosis, to being short of physical strength after middle-aged and elderly people light activity, palpitating speed, chest pain, the effect of being significantly improved such as to feel dizzy.Reduced blood pressure by increase vascular permeability and elasticity, have good antihypertensive effect.
Every Chinese medicine is used alone effect of its blood pressure lowering and blood fat and not obvious above, and the present invention, by all taste Chinese medicine reasonable compatibilities, plays the effect of Synergistic, effectively can play the effect of blood pressure lowering and blood fat.
Lepidinm meyenii Walp, Semen Cassiae and other drug extract by the present invention respectively, adopt different extracting method for different medicinal properties, extracts active ingredients more abundant.
The mutual tonification of the various composition of the present invention, has the effect of Synergistic, has significant effect to blood pressure lowering and blood fat.
Detailed description of the invention
Embodiment 1
Take pueraria root powder 50kg, Radix Puerariae 10 kg, Rhizoma Gastrodiae 20 kg, curcuma powder 45 kg, Semen Cassiae 20 kg, Folium Ginkgo 5 kg.
Preparation Maca extract:
1. dried by fresh Lepidinm meyenii Walp, dry under 35 ~ 45 DEG C of conditions, be ground into 60-120 object fine powder, add water boiling and extraction 1-2 time of 5-15 times amount, each 1-4 hour, filter, when making filtrate be concentrated into 20 DEG C, relative density is 1.1 ~ 1.3, dry;
2. by step 1. dry thing 75 ~ 85% alcoholic solution of gained extract under the condition of reflow treatment, extraction time 20-40 minute, filtration, after making the mode drying of filtrate concentrating, spray-dried or drying under reduced pressure and get final product; Filtrate is concentrated is vacuum concentration at the temperature of 60 ~ 70 DEG C, and its vacuum is-0.050 ± 0.01Mpa.
Prepare Radix Puerariae, Rhizoma Gastrodiae, Semen Cassiae, Folium Ginkgo extract:
First take Radix Puerariae, Rhizoma Gastrodiae, Folium Ginkgo make coarse powder respectively, with volume fraction 80-90% ethanol lixiviate 2 ~ 3 times, each lixiviate ethanol used be the 4-8 of raw material gross weight doubly, each extraction time is 15-20h, and each extraction temperature is 40-60 DEG C; Medicinal residues decoct with water secondary, first time 1-3 hour, and second time 2-4 hour, filters to get filtrate after collecting decoction and each lixiviate, be evaporated in concentrate alcohol-free at 55-65 DEG C;
Prepare Semen Cassiae extract:
Semen Cassiae powder is broken into 80 ~ 100 object fine powders, adds in 50-55 ° of Chinese liquor of 4-5 times of weight, at 20-35 DEG C of dipping 30-64 hour, obtain impregnation liquid; Filtered by impregnation liquid, impregnation liquid is heated to 55-60 DEG C to carry out carrying alcohol, when the proportion to extracting solution is more than 0.92 Baume, stops carrying alcohol;
Above-mentioned each material is carried out dehydration at 70-80 DEG C and concentrates to obtain concentrate.
Embodiment 2
Take pueraria root powder 55kg, Radix Puerariae 15 kg, Rhizoma Gastrodiae 25 kg, curcuma powder 50 kg, Semen Cassiae 25 kg, Folium Ginkgo 10 kg.
Preparation Maca extract:
1. dried by fresh Lepidinm meyenii Walp, dry under 35 ~ 45 DEG C of conditions, be ground into 60-120 object fine powder, add water boiling and extraction 1-2 time of 5-15 times amount, each 1-4 hour, filter, when making filtrate be concentrated into 20 DEG C, relative density is 1.1 ~ 1.3, dry;
2. by step 1. dry thing 75 ~ 85% alcoholic solution of gained extract under the condition of ultrasonic Treatment, filtration, after making the mode drying of filtrate concentrating, spray-dried or drying under reduced pressure and get final product; Hyperacoustic ultrasonic power is 350-400W/cm 2, extraction time 20-40 minute; Filtrate is concentrated is vacuum concentration at the temperature of 60 ~ 70 DEG C, and its vacuum is-0.050 ± 0.01Mpa.
Prepare Radix Puerariae, Rhizoma Gastrodiae, Semen Cassiae, Folium Ginkgo extract:
First take Radix Puerariae, Rhizoma Gastrodiae, Folium Ginkgo make coarse powder respectively, with volume fraction 80-90% ethanol lixiviate 2 ~ 3 times, each lixiviate ethanol used be the 4-8 of raw material gross weight doubly, each extraction time is 15-20h, and each extraction temperature is 40-60 DEG C; Medicinal residues decoct with water secondary, first time 1-3 hour, and second time 2-4 hour, filters to get filtrate after collecting decoction and each lixiviate, be evaporated in concentrate alcohol-free at 55-65 DEG C;
Prepare Semen Cassiae extract:
Semen Cassiae powder is broken into 80 ~ 100 object fine powders, adds in 50-55 ° of Chinese liquor of 4-5 times of weight, at 20-35 DEG C of dipping 30-64 hour, obtain impregnation liquid; Filtered by impregnation liquid, impregnation liquid is heated to 55-60 DEG C to carry out carrying alcohol, when the proportion to extracting solution is more than 0.92 Baume, stops carrying alcohol;
Above-mentioned each material is carried out dehydration at 70-80 DEG C and concentrates to obtain concentrate.
Embodiment 3
Take pueraria root powder 60kg, Radix Puerariae 20 kg, Rhizoma Gastrodiae 30 kg, curcuma powder 55 kg, Semen Cassiae 30v, Folium Ginkgo 15 kg.
Preparation Maca extract:
1. dried by fresh Lepidinm meyenii Walp, dry under 35 ~ 45 DEG C of conditions, be ground into 60-120 object fine powder, add water boiling and extraction 1-2 time of 5-15 times amount, each 1-4 hour, filter, when making filtrate be concentrated into 20 DEG C, relative density is 1.1 ~ 1.3, dry;
2. by step 1. dry thing 75 ~ 85% alcoholic solution of gained extract under the condition of reflow treatment, extraction time 20-40 minute, filtration, after making the mode drying of filtrate concentrating, spray-dried or drying under reduced pressure and get final product; Filtrate is concentrated is vacuum concentration at the temperature of 60 ~ 70 DEG C, and its vacuum is-0.050 ± 0.01Mpa.
Prepare Radix Puerariae, Rhizoma Gastrodiae, Semen Cassiae, Folium Ginkgo extract:
First take Radix Puerariae, Rhizoma Gastrodiae, Folium Ginkgo make coarse powder respectively, with volume fraction 80-90% ethanol lixiviate 2 ~ 3 times, each lixiviate ethanol used be the 4-8 of raw material gross weight doubly, each extraction time is 15-20h, and each extraction temperature is 40-60 DEG C; Medicinal residues decoct with water secondary, first time 1-3 hour, and second time 2-4 hour, filters to get filtrate after collecting decoction and each lixiviate, be evaporated in concentrate alcohol-free at 55-65 DEG C;
Prepare Semen Cassiae extract:
Semen Cassiae powder is broken into 80 ~ 100 object fine powders, adds in 50-55 ° of Chinese liquor of 4-5 times of weight, at 20-35 DEG C of dipping 30-64 hour, obtain impregnation liquid; Filtered by impregnation liquid, impregnation liquid is heated to 55-60 DEG C to carry out carrying alcohol, when the proportion to extracting solution is more than 0.92 Baume, stops carrying alcohol;
Above-mentioned each material is carried out dehydration at 70-80 DEG C and concentrates to obtain concentrate.
The present invention can make any dosage form according to common process pharmaceutically.
The Chinese traditional compound medicine made is carried out clinical trial.
Diagnostic criteria is:
Take without relapse indications after 1 year, belong to and curing.
Have after taking a course for the treatment of (within 30 days, being a course for the treatment of) and obviously alleviate or remove symptom more than 70% person, belong to effective.
Have after taking 1-2 the course for the treatment of and alleviate or eliminate symptom more than 50% person, belong to effectively.
More than a course for the treatment of without alleviating and eliminating symptom, invalid.
Clinical effectiveness is added up: in the crowd of 100 hypertension, hyperlipidemia,
Cure rate: 65%; Effective percentage: 100%; Obvious effective rate: 6%.
The curative effect of medicine of the present invention is proved further by the concrete case of following a few example.
Case 1
Certain man, 61 years old, obesity, the light red tongue of body of the tongue was greasy in vain, and high liver fire, easily flies into a rage.
Blood pressure systolic pressure 140 ~ 170 when not eating depressor, diastolic pressure is 90 ~ 105, eats FUFANG JIANGYA PIAN Western medicine, and infrequently eats depressor, and just ate when blood pressure is raised to more than 160.
It is 2.6mmol/L that blood drawing detects serum triglycerides.
Treatment: take medicine of the present invention (embodiment 1).Every day 2 ~ 3 times, each 15ml, period in a medicine avoids pungent, cold food.
Effect: take medicine after the course for the treatment of, blood pressure is in a slight decrease, and blood pressure neglect high situation make moderate progress, blood fat does not detect.
This patient continues to take for second course for the treatment of: take oral liquid of the present invention (embodiment 1), every day 3 times, each 15ml,
After taking two courses for the treatment of, blood pressure has had obvious reduction, and individual is in and detects systolic pressure 120 ~ 150 at ordinary times, and diastolic pressure is 75 ~ 95.
It is 2.1mmol/L that blood drawing detects serum triglycerides, also reduces a lot comparatively before.
Illustrate that Maca composite Chinese medicine preparation of the present invention has certain blood pressure lowering and the effect of blood fat.
Case 2
Certain female, 66 years old, red tongue, few tongue, high liver fire, easily flew into a rage.
Blood pressure systolic pressure 160 ~ 180 when not eating depressor, diastolic pressure is 100 ~ 110, eats the various western medicine of depressurization such as compound recipe reserpine, verticil, pargyline, FUFANG JIANGYA PIAN, felodipine sustained-release tablets, and drug withdrawal just repeatedly.
It is 2.8mmol/L that blood drawing detects serum triglycerides.
Treatment: take medicine of the present invention (embodiment 2), every day 3 times, each 15ml, period in a medicine avoids pungent, cold food.The depressor felodipine sustained-release tablets amount of eating at ordinary times is reduced by half.
Effect:
Take medicine course for the treatment of and when blood pressure lowering dose reduces by half, blood pressure is declined, and blood pressure is neglected high situation and made moderate progress, blood fat does not detect.
This patient continues to take for second course for the treatment of: or the depressor felodipine sustained-release tablets amount of eating at ordinary times is reduced by half, blood pressure has had obvious reduction, and individual is in and detects systolic pressure 120 ~ 140 at ordinary times, and diastolic pressure is 75 ~ 90.
This patient continues to take for the 3rd course for the treatment of: during this period, depressor felodipine sustained-release tablets is progressively removed, and finds that, while progressively removing depressor, blood pressure does not also rise, and individual is in and detects systolic pressure 120 ~ 140 at ordinary times, and diastolic pressure is 75 ~ 90.
It is 2.3mmol/L that blood drawing detects serum triglycerides, also reduces a lot comparatively before.
Illustrate that Maca composite Chinese medicine preparation of the present invention has certain blood pressure lowering and the effect of blood fat.
Case 3
Certain female, 76 years old, red tongue, few tongue, the deficiency of vital energy, weak, insomnia and dreamful sleep.
Blood pressure systolic pressure 130 ~ 160 when not eating depressor, diastolic pressure is 90 ~ 100, does not take medicine at ordinary times, eats FUFANG JIANGYA PIAN when feeling dizzy.
It is 2.3mmol/L that blood drawing detects serum triglycerides.
Treatment: take medicine of the present invention (embodiment 3), every day 3 times, each 15ml, period in a medicine avoids pungent, cold food.Effect:
Take medicine a course for the treatment of, blood pressure is controlled.
This patient continues to take for second course for the treatment of: after taking for second course for the treatment of, and blood pressure has had obvious reduction, and in one month, 2 dizzy phenomenons appear in early stage, and the later stage does not occur.
It is 2.3mmol/L that blood drawing detects serum triglycerides, also reduces a lot comparatively before.
It is 1.8mmol/L that blood drawing detects serum triglycerides, and blood fat also declines much.
Illustrate that Maca composite Chinese medicine preparation of the present invention has certain blood pressure lowering and the effect of blood fat.

Claims (4)

1. a Maca composite Chinese medicine preparation, is characterized in that, is to be grouped into by the one-tenth of following weight portion: pueraria root powder 50 ~ 60 parts, Radix Puerariae 10 ~ 20 parts, 20 ~ 30 parts, Rhizoma Gastrodiae, curcuma powder 45 ~ 55 parts, Semen Cassiae 20 ~ 30 parts, Folium Ginkgo 5 ~ 15 parts.
2. Maca composite Chinese medicine preparation according to claim 1, is characterized in that, is to be grouped into by the one-tenth of following weight portion: pueraria root powder 55 parts, Radix Puerariae 15 parts, 25 parts, Rhizoma Gastrodiae, curcuma powder 50 parts, Semen Cassiae 25 parts, Folium Ginkgo 10 parts.
3. a preparation method for Maca composite Chinese medicine preparation as claimed in claim 1, is characterized in that, comprise the steps:
(1) preparation of Maca extract:
1. dried by fresh Lepidinm meyenii Walp, dry under 35 ~ 45 DEG C of conditions, be ground into 60-120 object fine powder, add water boiling and extraction 1-2 time of 5-15 times amount, each 1-4 hour, filter, when making filtrate be concentrated into 20 DEG C, relative density is 1.1 ~ 1.3, dry;
2. by step 1. dry thing 75 ~ 85% alcoholic solution of gained extract under the condition of reflow treatment or the condition of ultrasonic Treatment, filtration, after making the mode drying of filtrate concentrating, spray-dried or drying under reduced pressure and get final product;
(2) preparation of Radix Puerariae, Rhizoma Gastrodiae, Semen Cassiae, Folium Ginkgo extract:
First take Radix Puerariae, Rhizoma Gastrodiae, Folium Ginkgo make coarse powder respectively, with volume fraction 80-90% ethanol lixiviate 2 ~ 3 times, each lixiviate ethanol used be the 4-8 of raw material gross weight doubly, each extraction time is 15-20h, and each extraction temperature is 40-60 DEG C; Medicinal residues decoct with water secondary, first time 1-3 hour, and second time 2-4 hour, filters to get filtrate after collecting decoction and each lixiviate, be evaporated in concentrate alcohol-free at 55-65 DEG C;
(3) preparation of Semen Cassiae extract:
Semen Cassiae powder is broken into 80 ~ 100 object fine powders, adds in 50-55 ° of Chinese liquor of 4-5 times of weight, at 20-35 DEG C of dipping 30-64 hour, obtain impregnation liquid; Filtered by impregnation liquid, impregnation liquid is heated to 55-60 DEG C to carry out carrying alcohol, when the proportion to extracting solution is more than 0.92 Baume, stops carrying alcohol;
(4) above-mentioned each material is carried out dehydration at 70-80 DEG C and concentrate to obtain concentrate.
4. the preparation method of Maca composite Chinese medicine preparation as claimed in claim 3, is characterized in that, step (1) 2. described in hyperacoustic ultrasonic power be 350-400W/cm 2, extraction time 20-40 minute; Filtrate is concentrated is vacuum concentration at the temperature of 60 ~ 70 DEG C, and its vacuum is-0.050 ± 0.01Mpa.
CN201410530795.7A 2014-10-11 2014-10-11 Maca compound traditional Chinese herb preparation and preparation method thereof Pending CN104225503A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105432808A (en) * 2015-07-15 2016-03-30 武汉华士特工业生物技术开发有限公司 Peruvian ginseng aromatic oil and preparation method
CN107485023A (en) * 2017-09-29 2017-12-19 武汉华士特工业生物技术开发有限公司 A kind of functional food composition containing maca and turmeric and its preparation method and application
WO2023133982A1 (en) * 2022-01-11 2023-07-20 Meng Qingxiong A composition for improving chronic inflammation of the prostate and calcified plaques of the prostate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101297950A (en) * 2008-05-15 2008-11-05 天科仁祥技术(北京)有限责任公司 Chinese medicine for preventing and treating atherosclerosis, coronary disease and preparation thereof
CN103627600A (en) * 2013-11-21 2014-03-12 贵州鑫吾福酒业有限公司 Maca healthcare wine and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101297950A (en) * 2008-05-15 2008-11-05 天科仁祥技术(北京)有限责任公司 Chinese medicine for preventing and treating atherosclerosis, coronary disease and preparation thereof
CN103627600A (en) * 2013-11-21 2014-03-12 贵州鑫吾福酒业有限公司 Maca healthcare wine and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105432808A (en) * 2015-07-15 2016-03-30 武汉华士特工业生物技术开发有限公司 Peruvian ginseng aromatic oil and preparation method
CN107485023A (en) * 2017-09-29 2017-12-19 武汉华士特工业生物技术开发有限公司 A kind of functional food composition containing maca and turmeric and its preparation method and application
WO2023133982A1 (en) * 2022-01-11 2023-07-20 Meng Qingxiong A composition for improving chronic inflammation of the prostate and calcified plaques of the prostate

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