CN104225109A - Chinese herbal preparation for treating stomach fire toothache and preparation method thereof - Google Patents
Chinese herbal preparation for treating stomach fire toothache and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese herbal preparation for treating stomach fire toothache. The preparation is mainly prepared by using the following main raw materials by weight: 40-80 parts of rush, 8-15 parts of tonkin pepper, 10-20 parts of kudzu vine root, 5-12 parts of medical stone, 20-40 parts of Chinese wolfberry root bark, 6-12 parts of rattletop, 8-15 parts of angelica sinensis, 6-9 parts of gypsum and 3-6 parts of aconitum sungpanense block root. The preparation is prepared according to the traditional Chinese medicine principle and the stomach fire toothache completely, has a good analgesic effect, can well treat the stomach fire toothache, is good in analgesic and detumescence effect, is quick in effect and capable of treating foul breath and has a very good treatment effect on the stomach fire toothache.
Description
Technical field
The present invention relates to traditional Chinese medicine field, especially relate to a kind of Chinese medicine preparation and method for making for the treatment of toothache due to stomach-fire.
Background technology
Toothache due to stomach-fire refers to lower tooth (periodontal disease) bitterly, is mostly that stomach-fire proceeds to tooth by the stomach channel of foot-Yang-ming, and the ground of tooth non-Tibetan fire, when tooth is got angry time, will make dental pain, gingiva also can become red and swollen.Toothache due to stomach-fire bitterly, accompanies swelling of the gum halitosis, constipation rolling pulse owing to accumulateing upper tapping tooth in the bright phlegm-fire of sun.The fire of the person, only stomach-fire is the most prosperous.In general, the reason causing stomach-fire to occur is a lot, eats too many Fructus Capsici often, drinks the food that too many Chinese liquor and so on is pungent.Toothache due to stomach-fire, except feeling to have an intense pain, also there will be red swelling of gingiva, pyorrhea or hemorrhage situation, and should have some can eliminating stomach-fire, and the food of cooling blood and relieving pain, as milk, shellfish, Fructus Colocasiae Esculentae and fresh red, yellow, and green color vegetable etc.This kind of toothache also will avoid pungent food, fried, hard, crude fibre food.In addition, the group food that fire-cures directly can stimulate periodontal mucosa, destroys the epithelial cell of mucosa, makes its hyperemia, edema, causes pain; Sugary, the high sweet food of fat has stimulation to gingiva, nondigestible again, also answers diet.
The main manifestations symptom of stomach-fire: gastrointestinal symptom shows as scorching hot pain, abdominal distention, xerostomia halitosis, the stool is completely mashed, constipation, gingival swelling and pain, has no appetite.Stomach-fire also divides deficiency and excess two kinds, asthenic fire show as cough a little, have no appetite, constipation, abdominal distention, red tongue, few tongue; Excess-fire shows as epigastric discomfort, dry mouth with bitter taste, stool are stiff.Namely stomach-fire is gastric heat.For being addicted to drink, the fire of moxibustion that improper diet causes such as pungent addicted to food, surfeit fat meat and fine grain is delicious, the traditional Chinese medical science is referred to as stomach-fire, is normally caused by damp and hot, dyspepsia two reasons.Meanwhile, fire of moxibustion also causes because of the amount of diet, matter and time three large reason.Stomach-fire Sheng person a little, seems forever not have enough to eat, and is that gastric heat is to the illusion of brain really; Contain to some stages to fire, there is inflammation phenomenon in stomach, what will become and all do not feel like eating, and can be described as that things turn into their opposites when they reach the extreme.The traditional Chinese medical science is thought, stomach-fire regulates should follow heat clearing away, principle stagnant clearly, alimentary abstinence, too the thing of steam is eaten less, and sweet greasy food is eaten less, and diet should increase yellow green vegetable and fruit in season, with the deficiency of vitimin supplement and inorganic salt, and suitably notice oral hygiene.
In the method for existing Chinese traditional treatment toothache due to stomach-fire, publication number CN103735750A(application number 201410027572.9) patent document discloses a kind of bag bubble collutory for the treatment of toothache, be made up of the raw material of following percentage by weight: Ampelopsis grossedentata 5-20%, Folium Polygoni Cuspidati 10-30%, Fructus Zanthoxyli 10-30%, Herba Asari 5-10%, Sal 5-30%.Publication number CN103272168A(application number 201310245477.1) patent document discloses a kind of Chinese medicine compound alleviating radiotherapy side effect and its preparation method and application, described Chinese medicine is the medicament adopting the raw material of following portions by weight proportioning to be prepared from: Radix Rehmanniae 40-60 part, Rhizoma Coptidis 5-20 part, Cortex Moutan 20-40 part, Rhizoma Cimicifugae 10-30 part, Gypsum Fibrosum 50-70 part, Radix Scutellariae 20-40 part, processs Rhizoma Anemarrhenae 20-40 part, Radix Et Rhizoma Rhei 5-15 part, Fructus Amomi 5-20 part, Flos Lonicerae 40-60 part.Publication number CN103638233A(application number 201310715329.1) patent document discloses a kind of Chinese medicine composition for the treatment of flaming up of stomach-fire type periodontitis, be made up of following raw material medicaments: thorn youth fruit 30-40 part, Cortex betulae platyphyllae 20-30 part, Caulis et Folium Pothi piluliferis 20-30 part, Herba Parnassiae foliosae 15-25 part, Rhizoma Coptidis 15-25 part, Folium Linderae strychnifoliae 15-25 part, Radix Cirsii Japonici 15-25 part, Rhizoma Corydalis 15-25 part, Radix Glycyrrhizae 8-15 part.
In a word, Chinese medicine achieves certain effect in treatment toothache due to stomach-fire, but also there are some problems: desirable not enough to the therapeutic effect of toothache due to stomach-fire clinically, needs to be improved further.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine preparation and the method for making of preparing simple, taking convenience, portable treatment toothache due to stomach-fire, this curative effect of medicine is definite and without any side effects.
Technical scheme of the present invention is:
The Chinese medicine preparation for the treatment of toothache due to stomach-fire, takes off the primary raw material stating weight proportion and is prepared from: Medulla Junci 40-60 part; Herba Piperris Tonkinensis 8-15 part; Radix Puerariae 10-20 part; Maifanitum 5-12 part; Cortex Lycii 20-40 part; Rhizoma Cimicifugae 6-12 part; Radix Angelicae Sinensis 8-15 part; Gypsum Fibrosum 6-9 part; Radix Aconiti Sungpanensis 3-6 part.
The Chinese medicine preparation for the treatment of toothache due to stomach-fire, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Medulla Junci 45-55 part; Herba Piperris Tonkinensis 10-13 part; Radix Puerariae 13-17 part; Maifanitum 7-10 part; Cortex Lycii 25-35 part; Rhizoma Cimicifugae 8-10 part; Radix Angelicae Sinensis 10-13 part; Gypsum Fibrosum 7-8 part; Radix Aconiti Sungpanensis 4-5 part.
The Chinese medicine preparation for the treatment of toothache due to stomach-fire, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Medulla Junci 50 parts; Herba Piperris Tonkinensis 12 parts; Radix Puerariae 15 parts; Maifanitum 8 parts; Cortex Lycii 30 parts; Rhizoma Cimicifugae 9 parts; Radix Angelicae Sinensis 12 parts; 7.5 parts, Gypsum Fibrosum; Radix Aconiti Sungpanensis 4.5 parts.
Present invention also offers and above-mentioned medicament is made pharmaceutically acceptable powder, thick paste agent, granule, pill or capsule.
The preparation method of described powder is:
(1) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), filter, gained filtrate is concentrated and dry, gained filtering residue is dried, pulverize together, cross 160-180 mesh sieve (preferred 165-175 mesh sieve, is more preferably 170 mesh sieves);
(2) Medulla Junci, Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis are placed in dehydrator and dry (preferably oven dry at 80-100 DEG C, dry at being more preferably at 90 DEG C), pulverize, cross 140-160 mesh sieve (preferred 145-155 mesh sieve, is more preferably 150 mesh sieves);
(3) by step (1)-(2) gains mix homogeneously, sterile packaged (encapsulating with every parcel 8g) is carried out by pharmaceutically accepted specification.
Instructions of taking: each 1 bag, with the warm boiled water of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
The preparation method of described thick paste agent is:
(1) by gauze bag (preferred 600-800 object gauze bag, is more preferably 700 object gauze bags) sterilizing 20-40 minute (preferred 25-35 minute is more preferably 30 minutes), by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 80-100 DEG C (be preferably heated to 85-95 DEG C, be more preferably and be heated to 90 DEG C), add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), add step (1) and step (2) gains, decoct 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes), filter;
(4) step (3) gained filtrate is concentrated into the preferred 1.25-1.35 of relative density 1.20-1.40(, be more preferably 1.30), add sucrose (consumption of preferably sucrose is the 5%-10% of filtrate quality, and the consumption being more preferably sucrose is 8% of filtrate quality), mix homogeneously, sterile packaged.
Instructions of taking: each 10g, with the warm boiled water of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
The preparation method of described granule is:
(1) by gauze bag (preferred 600-800 object gauze bag, is more preferably 700 object gauze bags) sterilizing 20-40 minute (preferred 25-35 minute is more preferably 30 minutes), by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 80-100 DEG C (be preferably heated to 85-95 DEG C, be more preferably and be heated to 90 DEG C), add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), add step (1) and step (2) gains, decoct 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes), filter;
(4) step (3) gained filtrate is concentrated into the preferred 1.25-1.35 of relative density 1.20-1.40(, be more preferably 1.30), (consumption of preferably sucrose is the 5%-10% of filtrate quality to add sucrose, the consumption being more preferably sucrose is 8% of filtrate quality), mix homogeneously, make the namely loose soft material that hands pinches agglomerating pressure, with fashion of extrusion by 14-22 eye mesh screen (preferred 16-20 eye mesh screen, be more preferably 18 eye mesh screens), make uniform granule, be aided with pharmaceutically acceptable carrier package.
Instructions of taking: each 10g, with the warm boiled water of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
The preparation method of described pill is:
(1) by gauze bag (preferred 600-800 object gauze bag, is more preferably 700 object gauze bags) sterilizing 20-40 minute (preferred 25-35 minute is more preferably 30 minutes), by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 80-100 DEG C (be preferably heated to 85-95 DEG C, be more preferably and be heated to 90 DEG C), add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), add step (1) and step (2) gains, decoct 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes), filter;
(4) step (3) gained filtrate is concentrated into the preferred 1.25-1.35 of relative density 1.20-1.40(, be more preferably 1.30), add starch (consumption of preferred starch is the 5%-10% of filtrate quality, and the consumption being more preferably starch is 8% of filtrate quality), mix homogeneously, be modulated into the soft material that light pressure is then loose, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, is more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;
(5) by Mel, (quality of preferred Mel is the 10%-18% of medicated powder quality, the quality being more preferably Mel is 15% of medicated powder quality) be placed in pot, temper with slow fire, endure to thick Deng Mel, mix the medicated powder of step (4) gained again, fully mix into ointment thoroughly, make pill by traditional Chinese medical science tradition pill method, obtain pill.
According to preparation method recited above, preferred scheme is: step (4) is dried at 70-90 DEG C (preferably, drying at 80 DEG C).
Instructions of taking: each 10-15 ball, with the warm water delivery service of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
The preparation method of described capsule is:
(1) by gauze bag (preferred 600-800 object gauze bag, is more preferably 700 object gauze bags) sterilizing 20-40 minute (preferred 25-35 minute is more preferably 30 minutes), by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 80-100 DEG C (be preferably heated to 85-95 DEG C, be more preferably and be heated to 90 DEG C), add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), add step (1) and step (2) gains, decoct 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes), filter;
(4) step (3) gained filtrate is concentrated into the preferred 1.25-1.35 of relative density 1.20-1.40(, be more preferably 1.30), add sucrose (consumption of preferably sucrose is the 5%-10% of filtrate quality, and the consumption being more preferably sucrose is 8% of filtrate quality), mix homogeneously, be modulated into the soft material that light pressure is then loose, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, is more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;
(5) step (4) gained medicated powder is measured according to 0.4-0.6g/ grain (preferred 0.45-0.55g/ grain, is more preferably 0.5g/ grain), be processed into capsule shape dosage form according to the preparation for processing of capsule.
According to preparation method recited above, preferred scheme is: step (4) is dried at 70-90 DEG C (preferably, drying at 80 DEG C).
Instructions of taking: each 2-3 grain, with the warm water delivery service of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Medulla Junci: sweet in the mouth, light, is slightly cold.GUIXIN, lung, small intestinal, urinary bladder channel.Another name Medulla Junci, Lin's grass, Herba Poae Sphondylodis, wild seat grass, the brown root of horse, wild horse palm fibre.For stem pith or the herb of rush family plant Medulla Junci.There is relieving stranguria by diuresis, effect of clearing heart fire.For gonorrhea, edema, hematuria, the puckery pain of oliguria, jaundice due to damp-heat, dysphoria and insomnia, the nocturnal fretfulness in infants, sore throat, aphtha of the mouth and tongue, wound.
Herba Piperris Tonkinensis: acrid in the mouth, warm in nature.Another name is blue, the large hemorrhoidal hamorrhage of askew leaf.For Piperaceae Piper plant optical axis ramie leaf Betel, be used as medicine with root or Herb.There is expelling wind and cold, disappear and examine effect of pain relieving.For bones and muscles pain due to rheumatism, treating swelling and pain by traumatic injury, cold syndrome of the stomach pain, dysmenorrhea, amenorrhea, Common Cold, poisonous snake, centipete bite.
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Return spleen, stomach warp.For the dry root of legume pueraria lobata.There is expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, effect of yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Maifanitum: sweet in the mouth, warm in nature.For Acid-intermediate igneous rock rocks beschtauite.Maifanitum main component has silicon dioxide, aluminium oxide, ferrum oxide, ferrous oxide, magnesium oxide, calcium oxide, sodium oxide, potassium oxide, titanium dioxide, phosphorus pentoxide, manganese oxide, carbon dioxide, and the trace element such as fluorine, sulfur, strontium, barium, copper, zinc.There is removing toxic substances and promoting granulation, effect of damp eliminating spleen invigorating.For carbuncle carbuncle on the back, acne, eczema, beriberi.
Cortex Lycii: sweet in the mouth, cold in nature.Return lung, liver, kidney channel.For the dry root bark of matrimony vine of solanaceae plant or lycium barbarum.There is removing heat from blood except steaming, effect of lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
Rhizoma Cimicifugae: acrid in the mouth, micro-sweet, cold nature.Return lung, spleen, stomach, large intestine channel.For the dry rhizome of ranunculaceae plant C.heracleifolia, Cimicifuga Dahurica or Rhizoma Cimicifugae.Have and deliver rash, heat-clearing and toxic substances removing, effect of elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome sends out speckle, proctoptosis, uterine prolapse.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.For the dry root of umbelliferae angelica.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow, for amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Gypsum Fibrosum: acrid in the mouth, sweet, cold in nature.Return stomach, lung meridian.For Sulfates Gypsum Fibrosum race mineral gypsum.Gypsum Fibrosum main component is hydrous calcium sulfate, still accompanies sand grains, clay, Organic substance, the impurity such as sulfide.Gypsum Fibrosum Preparatum is dead plaster.There is clearing away heat-fire, effect that relieving restlessness is quenched the thirst.For the high heat of calentura, excessive thirst, unconsciousness and delirium, goes mad, and sends out speckle dyspnea and cough due to lung-heat, heatstroke, stomach-fire headache, toothache, aphtha of the mouth and tongue.Forge then promoting tissue regeneration and ulcer healing, control ulcer sores burst do not close up, burn.
Radix Aconiti Sungpanensis: acrid in the mouth, warm in nature.Another name is the climing Radix Linderae, YANGJIAOQI, Radix Aconiti Kusnezoffii.For the tuber of Herba Ranunculi Japonici kind of plant Aconitum Sungpanense Hand-mazz.Have pain relieving, spasmolytic, anesthesia, relieves internal heat, wind-damp dispelling, effect of promoting blood circulation to remove blood stasis.For traumatic injury, impairment caused by overstrain, rheumatic arthritis, innominate toxic swelling, carbuncle furunculosis.
Medicament of the present invention, based on the principle of Chinese traditional treatment toothache due to stomach-fire, is make on the basis that have studied lot of documents, pharmacology work and clinical trial.This medicament selected materials is Chinese medicine material, without any side effects; And medical material medicine source is easy to get, medical material is with low cost, can not bring large financial burden to patient.This medicament is made according to the feature of Chinese medicine principle and toothache due to stomach-fire completely, has good analgesic effect, and can well treat toothache due to stomach-fire, alleviating pain and detumescence is effective, instant effect, and can remove halitosis, has good therapeutic effect to toothache due to stomach-fire.
Accompanying drawing explanation
Fig. 1 is alleviation situation of having a toothache after using the Traditional Chinese medicine preparation capsule of embodiment 5 gained treatment toothache due to stomach-fire;
Fig. 2 is appetite recovery situation after the Traditional Chinese medicine preparation capsule of use embodiment 5 gained treatment toothache due to stomach-fire.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the Chinese medicine preparation for the treatment of toothache due to stomach-fire, takes off the primary raw material stating weight proportion and is prepared from (getting 20g for every part): Medulla Junci 40 parts; Herba Piperris Tonkinensis 8 parts; Radix Puerariae 10 parts; Maifanitum 5 parts; Cortex Lycii 20 parts; Rhizoma Cimicifugae 6 parts; Radix Angelicae Sinensis 8 parts; 6 parts, Gypsum Fibrosum; Radix Aconiti Sungpanensis 3 parts.
The preparation method of the Chinese medicine preparation powder of above-mentioned treatment toothache due to stomach-fire is:
(1) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 40 minutes, filter, gained filtrate is concentrated and dry, and gained filtering residue is dried, and pulverizes together, crosses 170 mesh sieves;
(2) Medulla Junci, Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis are placed in dehydrator to dry, pulverize, cross 150 mesh sieves;
(3) by step (1)-(2) gains mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.
Instructions of taking: powder is divided 8g/ bag; Every day 2-3 time, each one bag, with warm boiled water, 2 days courses for the treatment of.
model case oneold XX, female, 56 years old, people from Mudan District, Heze city of Shandong province.Once because blood pressure raises, after the medicines such as oral An Bowei, blood pressure basic controlling was at normal level.Can not have in a few days, start have toothache, tooth acid, though go to a doctor in the department of stomatology repeatedly also can only alleviate multiple relapse to some extent, other symptoms of patient still have bitter taste, poor appetite; Sleep poor; Weak, " heart beating is slow ", after activity easily out of breath, breast is vexed; Easy perspiration etc.Patient figure is fat; Picture of the tongue: corpulent tongue is dark, tongue is white, thick greasy, Sublingual is slight blood stasis.Repeatedly seek medical advice, all do not fully recover.
Take the Chinese medicine preparation powder of embodiment 1 gained treatment toothache due to stomach-fire, adopt every day 3 times, each one bag, with warm boiled water, 2 days courses for the treatment of.Take the same day, toothache is just eased, and after having taken 1 course for the treatment of, the symptom of toothache tooth acid alleviates, and the symptoms such as poor appetite, weak and sleep difference are also eased.See this curative effect, CHENNU scholar determines the Chinese medicine preparation continuing to take embodiment 1 gained treatment toothache due to stomach-fire, and after having taken 2 courses for the treatment of, various malaise symptoms all disappears, and in order to prevent the recurrence again of the state of an illness, CHENNU scholar adheres to again having taken 1 course for the treatment of.Learn in the following up a case by regular visits to of later stage and fully recover, do not recur.
embodiment 2the Chinese medicine preparation for the treatment of toothache due to stomach-fire, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Medulla Junci 60 parts; Herba Piperris Tonkinensis 15 parts; Radix Puerariae 20 parts; Maifanitum 12 parts; Cortex Lycii 40 parts; Rhizoma Cimicifugae 12 parts; Radix Angelicae Sinensis 15 parts; 9 parts, Gypsum Fibrosum; Radix Aconiti Sungpanensis 6 parts.
The preparation method of the Chinese medicine preparation thick paste agent of above-mentioned treatment toothache due to stomach-fire is:
(1) by 700 object gauze bag sterilizing 30 minutes, by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 90 DEG C, add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 40 minutes, add step (1) and step (2) gains, decoct 30 minutes, filter;
(4) step (3) gained filtrate is concentrated into relative density 1.30, adds sucrose, mix homogeneously, sterile packaged.
Instructions of taking: each 10g, with the warm boiled water of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
model case twolee XX, female, 53 years old, people from Cao County, Heze city of Shandong province.Have a toothache 5 days in lower right side, sharp ache, and homonymy facial swelling can not be taken food, raw and cold thermostimulation exacerbation of symptoms, and cry time serious uneasy, night, larger dry stool, ate tablet for alleviating pain, antibiotic medicine after being ill always, all invalid.Look into and see: difficulty in opening mouth, the swelling of pain side surface part, gums is red and swollen, has halitosis taste, red tongue, dry, rough and yellow fur, arteries and veins flood.Diagnosis: toothache due to stomach-fire.
Take the Chinese medicine preparation thick paste agent of the treatment toothache due to stomach-fire of embodiment 2 gained, each 10g, with the warm boiled water of 35-45 DEG C, every day 3 times, after taking medicine 1 day, subjective symptoms is clearly better.After 2 days, symptom is remarkable, and face is swollen to disappear, and can dehisce to have a meal, large loose stool.After 4 days, subjective symptoms disappears, and subtracting dose is each 10g, and with the warm boiled water of 35-45 DEG C, every day 2 times, following the service takes 2 days, and recovery from illness, does not recur.
embodiment 3the Chinese medicine preparation for the treatment of toothache due to stomach-fire, takes off the primary raw material stating weight proportion and is prepared from (getting 20g for every part): Medulla Junci 45 parts; Herba Piperris Tonkinensis 10 parts; Radix Puerariae 13 parts; Maifanitum 7 parts; Cortex Lycii 25 parts; Rhizoma Cimicifugae 8 parts; Radix Angelicae Sinensis 10 parts; 7 parts, Gypsum Fibrosum; Radix Aconiti Sungpanensis 4 parts.
The preparation method of the Chinese medicine preparation granule of above-mentioned treatment toothache due to stomach-fire is:
(1) by 700 object gauze bag sterilizing 30 minutes, by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 90 DEG C, add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 40 minutes, add step (1) and step (2) gains, decoct 30 minutes, filter;
(4) step (3) gained filtrate is concentrated into relative density 1.30, adds sucrose, mix homogeneously, make the namely loose soft material that hands pinches agglomerating pressure, with fashion of extrusion by 18 eye mesh screens, make uniform granule, be aided with pharmaceutically acceptable carrier package.
Instructions of taking: each 10g, with the warm boiled water of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
model case threexue XX, man, 27 years old, people from Guangzhou, Guangdong.Being the boss of the little company in Guangzhou, is also a most typical toothache case.Once toothache outbreak at a time when the late into the night, pain must order he taken several tablet for alleviating pain.The next morning, his toothache is alleviated to some extent, but needs other places to go on business, and seeks medical advice so busy.Two days later, his having a toothache shows effect once again, and this time, cheek has also swollen slightly, and he almost cannot opening, and mouth turns up and all can have an intense pain a little, and except medicated porridge, he even cannot eat other things, and this has just removed stomatological hospital.Check as a result, stomach-fire causes various focusing depths represented, after cause and have an intense pain.After drop treats 1 day, symptom is eased, and just worries work again.Fatigue in work, adds thought pressure, do not start again in a few days have a toothache severity, again and again, Mr. Xue turn from side to side unbearable.
Unintentionally, in once going on business, listening client to describe the present invention, to treat the Chinese medicine preparation curative effect of toothache due to stomach-fire pretty good.So take the Chinese medicine preparation granule of the treatment toothache due to stomach-fire of embodiment 3 gained, take toothache on the same day and just alleviate to some extent, after having taken 1 course for the treatment of, except some hard things, most food can eat.See this curative effect, Mr. Xue is very delight, and after adhering to again taking 1 curative effect, also substantially do not have the sensation of pain when eating, the cheek of swelling has also recovered, and continue to take 1 course for the treatment of and consolidate, various malaise symptoms all disappears.Learn in the following up a case by regular visits to of later stage, by that time, do not recur in the time more than a year, Mr. Xue was very delight for this reason.
embodiment 4the Chinese medicine preparation for the treatment of toothache due to stomach-fire, takes off the primary raw material stating weight proportion and is prepared from (getting 15g for every part): Medulla Junci 55 parts; Herba Piperris Tonkinensis 13 parts; Radix Puerariae 17 parts; Maifanitum 10 parts; Cortex Lycii 35 parts; Rhizoma Cimicifugae 10 parts; Radix Angelicae Sinensis 13 parts; 8 parts, Gypsum Fibrosum; Radix Aconiti Sungpanensis 5 parts.
The preparation method of the Chinese medicine preparation pill of above-mentioned treatment toothache due to stomach-fire is:
(1) by 700 object gauze bag sterilizing 30 minutes, by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 90 DEG C, add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 40 minutes, add step (1) and step (2) gains, decoct 30 minutes, filter;
(4) step (3) gained filtrate is concentrated into relative density 1.30, adds starch, mix homogeneously, be modulated into the soft material that light pressure is then loose, cross 100 mesh sieves, dry, pulverize, obtain medicated powder;
(5) Mel is placed in pot, tempers with slow fire, wait Mel to endure to thick, then mix the medicated powder of step (4) gained, fully mix into ointment thoroughly, make pill by traditional Chinese medical science tradition pill method, obtain pill.
Instructions of taking: each 10-15 ball, with the warm water delivery service of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
model case fourxu XX, female, 49 years old, Accessories during Binzhou, Shandong Province from Boxing County.Toothache recurrent exerbation, repeatedly controls and does not heal.Diagnosis is at that time because gastric heat constipation, turbid YIN failing to descend and cause toothache due to stomach-fire, have purchased 1 course for the treatment of of Chinese medicine preparation pill that the present invention treats toothache due to stomach-fire, when up to having spent tens yuan.Be dirt cheap! So Mrs Xu does not believe that the curative effect of this medicament very well, just can be dropped into it in drawer after going home, separately go large hospitalize.But toothache still in the same old way.One evening, Mrs Xu cannot stand because pain obtains.Suddenly, remember also having medicament in drawer, why not do not have a try.After taking, soon, seem to have a toothache and take a turn for the better to some extent, so, determine that cheap medicament to take.Second day, toothache slow down, and Mrs Xu has the Chinese medicine preparation of the treatment toothache due to stomach-fire of embodiment 4 gained that have purchased 1 course for the treatment of, and after having taken, various malaise symptoms disappears.Learn in the following up a case by regular visits to of later stage, the toothache of Mrs Xu has thoroughly been cured, and does not recur again.
embodiment 5the Chinese medicine preparation for the treatment of toothache due to stomach-fire, takes off the primary raw material stating weight proportion and is prepared from (getting 20g for every part): Medulla Junci 50 parts; Herba Piperris Tonkinensis 12 parts; Radix Puerariae 15 parts; Maifanitum 8 parts; Cortex Lycii 30 parts; Rhizoma Cimicifugae 9 parts; Radix Angelicae Sinensis 12 parts; 7.5 parts, Gypsum Fibrosum; Radix Aconiti Sungpanensis 4.5 parts.
The preparation method of the Traditional Chinese medicine preparation capsule of above-mentioned treatment toothache due to stomach-fire is:
(1) by 700 object gauze bag sterilizing 30 minutes, by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 90 DEG C, add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 40 minutes, add step (1) and step (2) gains, decoct 30 minutes, filter;
(4) step (3) gained filtrate is concentrated into relative density 1.30, adds sucrose, mix homogeneously, be modulated into the soft material that light pressure is then loose, cross 100 mesh sieves, dry, pulverize, obtain medicated powder;
(5) step (4) gained medicated powder is measured according to 0.5g/ grain, be processed into capsule according to the preparation for processing of capsule.
Instructions of taking: each 2-3 grain, with the warm water delivery service of 35-45 DEG C, every day 3 times, 2 days courses for the treatment of.
test examplethe clinical practice of the Traditional Chinese medicine preparation capsule of embodiment 5 gained treatment toothache due to stomach-fire: in November ,-2010 in February, 2008, screen 250 routine patients in Duo Suo hospital, wherein women 121 example, male 129 example.Before test 2 weeks, carry out Continuous Observation to this crowd, record symptom and change, be divided into experimental group and matched group at random, wherein, experimental group has 150 people, and matched group has 100 people.Experimental group takes the Traditional Chinese medicine preparation capsule of embodiment 5 gained treatment toothache due to stomach-fire, each 2-3 grain, with the warm water delivery service of 35-45 DEG C, and every day 3 times, 2 days courses for the treatment of.Matched group takes other medicine (conventional medication such as peace, ibuprofen of having a toothache), takes every day twice (warm), each 2-4 sheet (adjusting to some extent depending on concrete condition), 2 days courses for the treatment of.Curative effect situation criterion: cure: take 2 courses for the treatment of, the transference cures such as toothache; Effective: to take 2 courses for the treatment of, toothache symptom alleviates or partial disappearance; Invalid: to take 2 courses for the treatment of, toothache symptom is unchanged or recur.
Observation period is limited to 4 days, and observed content is as follows:
1, within 1 day, be an observation cycle, record the alleviation situation of toothache, add up each cycle and to have a toothache the ratio be eased, result is as accompanying drawing 1:
Analyze: as can be seen from accompanying drawing 1, the analgesic effect of the Traditional Chinese medicine preparation capsule of embodiment 5 gained treatment toothache due to stomach-fire is better, has better therapeutical effect to toothache, more than the good effect of the matched group of use other drug.
2, within 1 day, be an observation cycle, record the diet of patient, add up the ratio that each cycle appetite is recovered, result is as accompanying drawing 2:
Analyze: as can be seen from accompanying drawing 2, embodiment 5 gained treats the faster of the diet recovery of the patient of the Traditional Chinese medicine preparation capsule of toothache due to stomach-fire, can infer the good effect of curative effect more than the matched group of use other drug of the experimental group of the Traditional Chinese medicine preparation capsule use embodiment 5 gained treatment toothache due to stomach-fire.
3, use the matched group of other drug to compare with the curative effect of the experimental group using the Traditional Chinese medicine preparation capsule of embodiment 5 gained treatment toothache due to stomach-fire, result is as shown in table 1:
Table 1: take rear therapeutic effect proving and comparisom
As can be seen from Table 1: take the cure rate of the experimental group of the Traditional Chinese medicine preparation capsule of embodiment 5 gained treatment toothache due to stomach-fire up to 80%, and the cure rate taking the matched group of other drug is only 43%; The effective percentage of experimental group is 98%, and inefficiency is only 2%, and the effective percentage of matched group is only 84%, and inefficiency is but up to 16%.So the successful taking the Traditional Chinese medicine preparation capsule of the treatment toothache due to stomach-fire of the embodiment of the present invention 5 gained is better than taking the curative effect of the matched group of other drug.
As can be seen from accompanying drawing 1-2: the curative effect taking the experimental group of the Traditional Chinese medicine preparation capsule of the treatment toothache due to stomach-fire of embodiment 5 gained is more than the good effect of matched group taking other drug.Wherein, the 1st day that takes, toothache remission aspect: the alleviation ratio of experimental group is up to 52%, and matched group is only 38%; When the 4th day, the alleviation ratio of experimental group reaches 96%, and matched group only reaches 76%.In appetite recovery: take the 1st day, the alleviation ratio of experimental group just reaches 51%, and matched group is only 35%, and when taking the 4th day, experimental group is alleviated ratio and reached 94%, and matched group is only 75%.Can draw, the present invention treats the more remarkable treatment effect of the Chinese medicine preparation of toothache due to stomach-fire, is the medicament that a kind of curative effect treats toothache more significantly, is especially applicable to the toothache that treatment stomach-fire causes.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the Chinese medicine preparation of toothache due to stomach-fire, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Medulla Junci 40-60 part; Herba Piperris Tonkinensis 8-15 part; Radix Puerariae 10-20 part; Maifanitum 5-12 part; Cortex Lycii 20-40 part; Rhizoma Cimicifugae 6-12 part; Radix Angelicae Sinensis 8-15 part; Gypsum Fibrosum 6-9 part; Radix Aconiti Sungpanensis 3-6 part.
2. Chinese medicine preparation according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Medulla Junci 45-55 part; Herba Piperris Tonkinensis 10-13 part; Radix Puerariae 13-17 part; Maifanitum 7-10 part; Cortex Lycii 25-35 part; Rhizoma Cimicifugae 8-10 part; Radix Angelicae Sinensis 10-13 part; Gypsum Fibrosum 7-8 part; Radix Aconiti Sungpanensis 4-5 part.
3. Chinese medicine preparation according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Medulla Junci 50 parts; Herba Piperris Tonkinensis 12 parts; Radix Puerariae 15 parts; Maifanitum 8 parts; Cortex Lycii 30 parts; Rhizoma Cimicifugae 9 parts; Radix Angelicae Sinensis 12 parts; 7.5 parts, Gypsum Fibrosum; Radix Aconiti Sungpanensis 4.5 parts.
4., according to the arbitrary described Chinese medicine preparation of claim 1-3, it is characterized in that, this medicament is made pharmaceutically acceptable powder, thick paste agent, granule, pill or capsule.
5. Chinese medicine preparation according to claim 4, is characterized in that, the preparation method of described powder, and step is as follows:
(1) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), filter, gained filtrate is concentrated and dry, gained filtering residue is dried, pulverize together, cross 160-180 mesh sieve (preferred 165-175 mesh sieve, is more preferably 170 mesh sieves);
(2) Medulla Junci, Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis are placed in dehydrator and dry (preferably oven dry at 80-100 DEG C, dry at being more preferably at 90 DEG C), pulverize, cross 140-160 mesh sieve (preferred 145-155 mesh sieve, is more preferably 150 mesh sieves);
(3) by step (1)-(2) gains mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.
6. Chinese medicine preparation according to claim 4, is characterized in that, the preparation method of described thick paste agent, and step is as follows:
(1) by gauze bag (preferred 600-800 object gauze bag, is more preferably 700 object gauze bags) sterilizing 20-40 minute (preferred 25-35 minute is more preferably 30 minutes), by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 80-100 DEG C (be preferably heated to 85-95 DEG C, be more preferably and be heated to 90 DEG C), add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), add step (1) and step (2) gains, decoct 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes), filter;
(4) step (3) gained filtrate is concentrated into the preferred 1.25-1.35 of relative density 1.20-1.40(, be more preferably 1.30), add sucrose (consumption of preferably sucrose is the 5%-10% of filtrate quality, and the consumption being more preferably sucrose is 8% of filtrate quality), mix homogeneously, sterile packaged.
7. Chinese medicine preparation according to claim 4, is characterized in that, the preparation method of described granule, and step is as follows:
(1) by gauze bag (preferred 600-800 object gauze bag, is more preferably 700 object gauze bags) sterilizing 20-40 minute (preferred 25-35 minute is more preferably 30 minutes), by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 80-100 DEG C (be preferably heated to 85-95 DEG C, be more preferably and be heated to 90 DEG C), add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), add step (1) and step (2) gains, decoct 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes), filter;
(4) step (3) gained filtrate is concentrated into the preferred 1.25-1.35 of relative density 1.20-1.40(, be more preferably 1.30), (consumption of preferably sucrose is the 5%-10% of filtrate quality to add sucrose, the consumption being more preferably sucrose is 8% of filtrate quality), mix homogeneously, make the namely loose soft material that hands pinches agglomerating pressure, with fashion of extrusion by 14-22 eye mesh screen (preferred 16-20 eye mesh screen, be more preferably 18 eye mesh screens), make uniform granule, be aided with pharmaceutically acceptable carrier package.
8. Chinese medicine preparation according to claim 4, is characterized in that, the preparation method of described pill, and step is as follows:
(1) by gauze bag (preferred 600-800 object gauze bag, is more preferably 700 object gauze bags) sterilizing 20-40 minute (preferred 25-35 minute is more preferably 30 minutes), by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 80-100 DEG C (be preferably heated to 85-95 DEG C, be more preferably and be heated to 90 DEG C), add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), add step (1) and step (2) gains, decoct 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes), filter;
(4) step (3) gained filtrate is concentrated into the preferred 1.25-1.35 of relative density 1.20-1.40(, be more preferably 1.30), add starch (consumption of preferred starch is the 5%-10% of filtrate quality, and the consumption being more preferably starch is 8% of filtrate quality), mix homogeneously, be modulated into the soft material that light pressure is then loose, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, is more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;
(5) by Mel, (quality of preferred Mel is the 10%-18% of medicated powder quality, the quality being more preferably Mel is 15% of medicated powder quality) be placed in pot, temper with slow fire, endure to thick Deng Mel, mix the medicated powder of step (4) gained again, fully mix into ointment thoroughly, make pill by traditional Chinese medical science tradition pill method, obtain pill.
9. Chinese medicine preparation according to claim 4, is characterized in that, the preparation method of described capsule, and step is as follows:
(1) by gauze bag (preferred 600-800 object gauze bag, is more preferably 700 object gauze bags) sterilizing 20-40 minute (preferred 25-35 minute is more preferably 30 minutes), by Medulla Junci drying and crushing, load in gauze bag;
(2) get the coarse sand of uniform particles cleaning, put in pot and be heated to 80-100 DEG C (be preferably heated to 85-95 DEG C, be more preferably and be heated to 90 DEG C), add Herba Piperris Tonkinensis, Radix Puerariae, Cortex Lycii, Rhizoma Cimicifugae, Radix Angelicae Sinensis and Radix Aconiti Sungpanensis, stir-fry, make medical material thermally equivalent, fry and heave gradually to surface, sieve removes the grains of sand;
(3) Maifanitum and Gypsum Fibrosum are smashed, be placed in marmite, decoct with water 30-50 minute (preferred 35-45 minute, be more preferably 40 minutes), add step (1) and step (2) gains, decoct 20-40 minute (preferred 25-35 minute, be more preferably 30 minutes), filter;
(4) step (3) gained filtrate is concentrated into the preferred 1.25-1.35 of relative density 1.20-1.40(, be more preferably 1.30), add sucrose (consumption of preferably sucrose is the 5%-10% of filtrate quality, and the consumption being more preferably sucrose is 8% of filtrate quality), mix homogeneously, be modulated into the soft material that light pressure is then loose, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, is more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;
(5) step (4) gained medicated powder is measured according to 0.4-0.6g/ grain (preferred 0.45-0.55g/ grain, is more preferably 0.5g/ grain), be processed into capsule shape dosage form according to the preparation for processing of capsule.
10. the preparation method of the Chinese medicine preparation according to Claim 8 described in-9, is characterized in that: step (4) is dried at 70-90 DEG C (preferably, drying at 80 DEG C).
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| WO1998018479A1 (en) * | 1996-10-25 | 1998-05-07 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Use of ginkgo biloba flavonoidic extract substantially devoid or terpenes for oral hygiene and composition containing such extract |
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