CN104203324B - 提供改善的皮肤凉爽的用户界面装置 - Google Patents

提供改善的皮肤凉爽的用户界面装置 Download PDF

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Publication number
CN104203324B
CN104203324B CN201380016788.9A CN201380016788A CN104203324B CN 104203324 B CN104203324 B CN 104203324B CN 201380016788 A CN201380016788 A CN 201380016788A CN 104203324 B CN104203324 B CN 104203324B
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CN
China
Prior art keywords
user interface
flow
pad
housing member
interface elements
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201380016788.9A
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English (en)
Chinese (zh)
Other versions
CN104203324A (zh
Inventor
N·P·威拉德
C·P·亨德里克斯
W·波泽
R·M·J·冯克恩
S·阿斯瓦蒂
J·范扎恩坦恩
M·克莱
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CN104203324A publication Critical patent/CN104203324A/zh
Application granted granted Critical
Publication of CN104203324B publication Critical patent/CN104203324B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/10Cooling bags, e.g. ice-bags
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057Pumps therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks
    • A61M16/0605Means for improving the adaptation of the mask to the patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks
    • A61M16/0605Means for improving the adaptation of the mask to the patient
    • A61M16/0616Means for improving the adaptation of the mask to the patient with face sealing means comprising a flap or membrane projecting inwards, such that sealing increases with increasing inhalation gas pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks
    • A61M16/0605Means for improving the adaptation of the mask to the patient
    • A61M16/0616Means for improving the adaptation of the mask to the patient with face sealing means comprising a flap or membrane projecting inwards, such that sealing increases with increasing inhalation gas pressure
    • A61M16/0622Means for improving the adaptation of the mask to the patient with face sealing means comprising a flap or membrane projecting inwards, such that sealing increases with increasing inhalation gas pressure having an underlying cushion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks
    • A61M16/0605Means for improving the adaptation of the mask to the patient
    • A61M16/0633Means for improving the adaptation of the mask to the patient with forehead support
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0002Head or parts thereof
    • A61F2007/0003Face
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/006Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit of gas
    • A61F2007/0061Using breath
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks
    • A61M2016/0661Respiratory or anaesthetic masks with customised shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606General characteristics of the apparatus related to heating or cooling cooled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/362General characteristics of the apparatus related to heating or cooling by gas flow
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Vascular Medicine (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
CN201380016788.9A 2012-03-27 2013-03-08 提供改善的皮肤凉爽的用户界面装置 Expired - Fee Related CN104203324B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261616024P 2012-03-27 2012-03-27
US61/616,024 2012-03-27
PCT/IB2013/051858 WO2013144753A1 (en) 2012-03-27 2013-03-08 User interface device providing for improved cooling of the skin

Publications (2)

Publication Number Publication Date
CN104203324A CN104203324A (zh) 2014-12-10
CN104203324B true CN104203324B (zh) 2017-07-14

Family

ID=48184265

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380016788.9A Expired - Fee Related CN104203324B (zh) 2012-03-27 2013-03-08 提供改善的皮肤凉爽的用户界面装置

Country Status (6)

Country Link
US (1) US10028859B2 (enExample)
EP (1) EP2830690B1 (enExample)
JP (1) JP6357144B2 (enExample)
CN (1) CN104203324B (enExample)
RU (1) RU2647153C2 (enExample)
WO (1) WO2013144753A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ729050A (en) * 2013-01-18 2018-08-31 ResMed Pty Ltd Patient interface and method for making same
CN106573122B (zh) * 2014-05-09 2019-07-05 费雪派克医疗保健有限公司 可定制呼吸面罩
US10065011B2 (en) 2014-05-21 2018-09-04 Atom Medical Corporation Gas supply mask apparatus
JP6271346B2 (ja) * 2014-06-12 2018-01-31 アトムメディカル株式会社 ガス類供給用マスク装置
EP2957314B1 (en) * 2014-06-17 2018-03-21 ResMed Ltd. Seal forming portion, pad and cushion for a patient interface
US10888678B2 (en) * 2014-08-28 2021-01-12 Koninklijke Philips N.V. CPAP pressurized gas permeable mask cushion
JP2016052489A (ja) * 2014-09-04 2016-04-14 高橋 勲 Cpapマスクの違和感軽減手段
JP7091401B2 (ja) * 2014-09-18 2022-06-27 レスメド・プロプライエタリー・リミテッド 患者インタフェースのためのガス洗浄ベント
WO2016041019A1 (en) 2014-09-18 2016-03-24 Resmed Limited Gas washout vent for patient interface
CN107921229A (zh) * 2015-07-20 2018-04-17 瑞思迈有限公司 具有体积缩减构件的患者接口
EP3352830B1 (en) 2015-09-23 2021-04-28 ResMed Pty Ltd Vent adaptor for a respiratory therapy system
WO2017207676A1 (en) * 2016-06-03 2017-12-07 Koninklijke Philips N.V. Cushion member and method of manufacturing same
US10507298B2 (en) * 2017-07-05 2019-12-17 Orel Yehuda SWENSON Respiration mask and seal therefor
JP7145939B2 (ja) * 2017-09-29 2022-10-03 コーニンクレッカ フィリップス エヌ ヴェ カスタマイズ可能なマスク及びそのサイズを合わせる方法
CN108653892A (zh) * 2018-06-07 2018-10-16 邹勤华 一种多功能无创呼吸机面罩
CN108671356B (zh) * 2018-06-07 2020-11-03 邹勤华 一种多功能无创呼吸机面罩
JP2020048927A (ja) * 2018-09-27 2020-04-02 日本光電工業株式会社 マスク
US11931512B2 (en) 2019-09-10 2024-03-19 ResMed Pty Ltd Oro-nasal patient interface
US11944752B2 (en) * 2019-12-20 2024-04-02 Koninklijke Philips N.V. Dimpled flap for a patient interface device
CN113532155B (zh) * 2020-04-03 2023-05-23 浙江大学 一种燃料电池温控系统高效换热器及其加工装置
EP4188497A4 (en) 2020-07-30 2024-08-28 ResMed Pty Ltd Seal-forming structure of patient interface with multiple sealing materials
US20230047153A1 (en) * 2021-08-16 2023-02-16 Min Yao Face mask

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101495170A (zh) * 2006-07-28 2009-07-29 雷斯梅德有限公司 呼吸治疗的传送系统
US20090223519A1 (en) * 2003-10-18 2009-09-10 Martin Eifler Ventilation mask
WO2011003130A1 (en) * 2009-07-06 2011-01-13 Compumedics Medical Innovation Pty Ltd Multiple chambers mask

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5438981A (en) 1993-09-30 1995-08-08 Respironics, Inc. Automatic safety valve and diffuser for nasal and/or oral gas delivery mask
US5655527A (en) 1994-06-03 1997-08-12 Respironics Inc. Respiratory mask with floating seal responsive to pressurized gas
AUPN417395A0 (en) * 1995-07-14 1995-08-10 Techbase Pty. Ltd. An improved spacer
US5921239A (en) * 1997-01-07 1999-07-13 Sunrise Medical Hhg Inc. Face mask for patient breathing
US5937851A (en) * 1997-02-27 1999-08-17 Respironics, Inc. Swivel device utilizing bearing clearance to allow carbon dioxide laden exhaust
US5819728A (en) 1997-10-07 1998-10-13 Ritchie; Scott C. Gas treatment hood
DE19840760C2 (de) * 1998-09-07 2000-07-20 Map Medizintechnik Gmbh Schalldämpfer für Beatmungsvorrichtung
US6581594B1 (en) * 2000-05-15 2003-06-24 Resmed Limited Respiratory mask having gas washout vent and gas washout vent for respiratory mask
US6957653B2 (en) * 2000-06-19 2005-10-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Flushed-seal respirator
JP4818569B2 (ja) * 2000-12-22 2011-11-16 レスメド・リミテッド マスク
DE10149908A1 (de) 2001-10-10 2003-04-17 Renate Wesner Vorrichtung zum Verbessern der Ein- und/oder Ausatemluft von Personen
US7052509B2 (en) * 2002-04-29 2006-05-30 Medcool, Inc. Method and device for rapidly inducing and then maintaining hypothermia
NZ595537A (en) * 2002-09-06 2013-05-31 Resmed Ltd Elbow with gas diversion baffle for respiratory mask
US7188622B2 (en) 2003-06-19 2007-03-13 3M Innovative Properties Company Filtering face mask that has a resilient seal surface in its exhalation valve
EP1646419B1 (de) 2003-07-09 2013-04-10 ResMed R&D Germany GmbH Atemmaskenanordnung
CN1988931B (zh) * 2004-07-23 2010-06-23 雷斯梅德有限公司 用于病人接口的排放弯管
WO2006024249A1 (de) 2004-09-03 2006-03-09 Weinmann Geräte für Medizin GmbH & Co. KG Vorrichtung zur beatmung
ES2443959T5 (es) * 2005-01-12 2018-04-02 Resmed Limited Almohadilla para interfaz con un paciente
WO2007012140A1 (en) * 2005-07-29 2007-02-01 Resmed Limited Method and apparatus for managing moisture buildup in pressurised breathing systems
US7937775B2 (en) 2005-08-09 2011-05-10 Microtek Medical, Inc. Surgical protective head gear assembly including high volume air delivery system
US20080142015A1 (en) * 2006-01-27 2008-06-19 David Groll Apparatus to provide continuous positive airway pressure
US9782553B2 (en) * 2007-07-13 2017-10-10 Resmed Limited Patient interface and non-invasive positive pressure ventilating method
EP2420281B1 (en) * 2007-08-24 2020-12-09 ResMed Pty Ltd Mask vent
US20090139525A1 (en) 2007-11-30 2009-06-04 Louis Schirm Comfort liner for pressure face masks and nasal masks
US20110253144A1 (en) * 2008-02-19 2011-10-20 David Groll Nasal Interface for Continuous Positive Airway Pressure Mask
TWM345618U (en) 2008-02-26 2008-12-01 Qbas Co Ltd Mask
US8365733B2 (en) 2008-05-29 2013-02-05 Rutan Robert M Liner for use with respiratory mask
US9901699B2 (en) 2008-06-04 2018-02-27 Resmed Limited Pad for a mask
EP3266483B1 (en) * 2008-08-04 2023-09-27 Fisher & Paykel Healthcare Limited Respiratory mask sealing interface
WO2010020874A2 (en) 2008-08-05 2010-02-25 Stewart Ruth Respiratory mask interface
US8397729B2 (en) * 2009-07-29 2013-03-19 Resmed R&D Germany Gmbh Surface structure on patient interface
WO2012052906A1 (en) * 2010-10-22 2012-04-26 Koninklijke Philips Electronics N.V. Fluid coupling conduit with exhaust gas noise reduction
US8925548B2 (en) * 2011-05-11 2015-01-06 Carefusion 207, Inc. Non-invasive ventilation facial skin protection
EP3878500B1 (en) * 2013-02-21 2024-04-03 Fisher & Paykel Healthcare Limited Patient interface with venting

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090223519A1 (en) * 2003-10-18 2009-09-10 Martin Eifler Ventilation mask
CN101495170A (zh) * 2006-07-28 2009-07-29 雷斯梅德有限公司 呼吸治疗的传送系统
WO2011003130A1 (en) * 2009-07-06 2011-01-13 Compumedics Medical Innovation Pty Ltd Multiple chambers mask

Also Published As

Publication number Publication date
JP2015511521A (ja) 2015-04-20
US10028859B2 (en) 2018-07-24
RU2014143058A (ru) 2016-05-20
EP2830690A1 (en) 2015-02-04
JP6357144B2 (ja) 2018-07-11
US20150040909A1 (en) 2015-02-12
CN104203324A (zh) 2014-12-10
WO2013144753A1 (en) 2013-10-03
EP2830690B1 (en) 2017-08-02
RU2647153C2 (ru) 2018-03-14

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