CN104198255B - One kind is based on microscopical cell point device for mark and microscope - Google Patents
One kind is based on microscopical cell point device for mark and microscope Download PDFInfo
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- CN104198255B CN104198255B CN201410498599.6A CN201410498599A CN104198255B CN 104198255 B CN104198255 B CN 104198255B CN 201410498599 A CN201410498599 A CN 201410498599A CN 104198255 B CN104198255 B CN 104198255B
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- microscopical
- point device
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Abstract
The present invention relates to a kind of be based on microscopical cell point device for mark and microscope, this cell point device for mark includes：Fixed part, is used for being fixed on microscope；Connecting portion, is connected with described fixed part；And point mark portion, it is connected with described connecting portion, the ending vertical ground in described point mark portion points to described microscopical smooth Lu Zhizheng, for being marked to the target location on object stage.Described microscope includes this cell point device for mark.The cell point device for mark that the present embodiment provides, can be fixed on microscope, as long as by a center for mark portion aligming microscope light path, just can be made marks to target cell by lower pressure point mark portion, accuracy is high, saves manpower；And by regulating tank is opened up on fixed part, convenient regulation position on microscope for the cell point device for mark.
Description
Technical field
The present invention relates to microscopy field, more particularly, to one kind based on microscopical cell point device for mark and include being somebody's turn to do
The microscope of cell point device for mark.
Background technology
Transmission electron microscope (Transmission electron microscope, TEM) technology is detection and studies
The important means of virus, is to diagnose one of one preferred technique of unknown cause of disease and identification biological terrorist cause of disease.Ultrathin section skill
Art is the important technology of the biological TEM technical system of composition.Under normal circumstances, adhere-wall culture cell ultrathin section sample making course needs
Following steps complete：First directly with cell sleaker scrape de- cell or by pancreatin digestion make cell detachment cultivate interface, then will
The cell of de- wall carries out centrifugation makes it be gathered into agglomerate, and then cell mass is carried out with aldehydes and the double fixing, gradient of Osmic acid.
Ethanol (or expoxy propane or acetone) dehydration, resin infiltrate, embed, being polymerized, repairing the processing routines such as block and section.Scraping and enzyme disappear
Change etc. and to comprehend and lead to cell ultrastructure to change, thus being difficult to reflect the true nature state of attached cell.Above-mentioned place
Reason makes cell detachment fixed position, assembles through centrifugation and forms agglomerate so that cell is randomly dispersed in cell mass, passes through
After above-mentioned process, section there are a lot of cells it is difficult to realize by observed by transmission electron microscope observation optical microscope
The same cell arriving, greatly reduces the detection efficiency to cell ultrathin section for the transmission electron microscope.
In order to observe target cell observed by optical microscope under transmission electron microscope, applicant's
A patent previously establishes the locating super-thin microtomy (patent of Application No. 201310470347.8《One kind is directed to
The locating super-thin dicing method of the sick cell of infection virus》).When applying locating super-thin microtomy, cutting for convenience
The position of labelling target cell before piece, is marked to target cell position generally in the way of manual, and concrete grammar is
The position of marking pen labelling target cell on microscope slide is used in microscope field of view.Because manual markings are micron-sized thin
Born of the same parents position difficulty for manual operations is larger, thus has higher requirement to operator, for example, require operator to have well
Arm stability, arm shake can not occur in labeling process and it needs to operator possess good vertical under microscope
Body-sensing etc..Once hand occurs a little shake, the position away from target cell for the mark position will be led to.In addition, for labelling
The nib of marking pen is general relatively thick, and the size in labeling dye region is much larger than target cell region, and this also leads to mark position not
Accurately.As described above, the manual mode accuracy that cell position is marked and efficiency are all relatively low.
Content of the invention
Technical problem
In view of this, the technical problem to be solved in the present invention is, how precise and high efficiency to the target cell on microscope slide
Position be marked, to facilitate the follow-up positioning searching for target cell, separate cell and to carry out the super of target cell
Slice.
Solution
In order to solve above-mentioned technical problem, according to one embodiment of the invention, there is provided one kind is based on microscopical cell
Point device for mark, including：
Fixed part, is used for being fixed on microscope；
Connecting portion, is connected with described fixed part；And
Point mark portion, is connected with described connecting portion, and the ending vertical ground in described point mark portion points in described microscopical light path
The heart, for being marked to the target location on object stage.
For above-mentioned based on microscopical cell point device for mark, in a kind of possible implementation, on described fixed part
Offer at least one pair of regulating tank, described regulating tank is located on horizontal direction and/or vertical direction.
For above-mentioned based on microscopical cell point device for mark, in a kind of possible implementation, described point mark portion bag
Include：
Casting die, is arranged on one end away from described fixed part of described connecting portion by elastomeric element；And
Point tender, is arranged on described casting die with the direction perpendicular to described object stage, is hollow structure.
In order to solve above-mentioned technical problem, according to another embodiment of the present invention, additionally provide a kind of microscope, including on
State based on microscopical cell point device for mark.
In order to solve above-mentioned technical problem, according to still another embodiment of the invention, additionally provide one kind based on microscopical
Cell point device for mark, including：
Fixed part, is used for being fixed on microscope；
Adjustment portion, is connected with described fixed part, and the length and width of described adjustment portion can be adjusted；And
Point mark portion, is connected with described fixed part, and the ending vertical ground in described point mark portion points in described microscopical light path
The heart, for being marked to the target location on object stage.
For above-mentioned based on microscopical cell point device for mark, in a kind of possible implementation, described fixed part bag
Include：
Fixed plate, described fixed plate offers at least one pair of regulating tank, and described regulating tank is located at horizontal direction and/or erects
Nogata is upwards；And
Connector, is rotatably coupled in the horizontal direction with described adjustment portion.
For above-mentioned based on microscopical cell point device for mark, in a kind of possible implementation, described connector with
The part that described adjustment portion connects carries out locking by pin.
For above-mentioned based on microscopical cell point device for mark, in a kind of possible implementation, described adjustment portion bag
Include：
First regulating part, described first regulating part is provided with slide rail on the length direction along described adjustment portion；And
Second regulating part, described second regulating part is provided with slide block on the length direction along described adjustment portion, described cunning
Block slides in described slide rail, and described slide block is provided with securing member.
For above-mentioned based on microscopical cell point device for mark, in a kind of possible implementation, described slide block setting
On slider carrier, described slider carrier is connected with described second regulating part by screw.
For above-mentioned based on microscopical cell point device for mark, in a kind of possible implementation, the end of described slide rail
Portion is provided with block piece and locating part.
For above-mentioned based on microscopical cell point device for mark, in a kind of possible implementation, described point mark portion bag
Include：
Casting die, is arranged on one end away from described fixed part of described adjustment portion by elastomeric element；And
Point tender, is arranged on described casting die with the direction perpendicular to described object stage, is hollow structure.
In order to solve above-mentioned technical problem, according to one more embodiment of the present invention, there is provided a kind of microscope, including above-mentioned
Based on microscopical cell point device for mark.
Beneficial effect
The present embodiment provide based on microscopical cell point device for mark, can be fixed on microscope, as long as by mark
The center of portion's aligming microscope light path, just can be made marks to target cell by lower pressure point mark portion, and accuracy is high, save
Manpower.And by regulating tank is opened up on fixed part, convenient regulation position on microscope for the cell point device for mark.Further
Ground, the length and width due to adjustment portion can be adjusted, so that this cell point device for mark can be applied to different size
Microscope on.The cell point device for mark that the present invention provides, can replace manually easily realizing essence to the position of micron order cell
Really labelling, to operator's no particular/special requirement, simple to operate, degree of accuracy is high, reproducible it is easy to promote.
According to below with reference to the accompanying drawings, to detailed description of illustrative embodiments, the further feature of the present invention and aspect will become
Clear.
Brief description
Comprise in the description and constitute the accompanying drawing of a part of description and description together illustrates the present invention's
Exemplary embodiment, feature and aspect, and for explaining the principle of the present invention.
Fig. 1 illustrates the structural representation based on microscopical cell point device for mark providing according to one embodiment of the invention
Figure；
Fig. 2 illustrates the structural representation based on microscopical cell point device for mark providing according to a further embodiment of the invention
Figure；
Fig. 3 illustrates the front view based on microscopical cell point device for mark providing according to a further embodiment of the invention；
Fig. 4 illustrates the top view based on microscopical cell point device for mark providing according to a further embodiment of the invention；
Fig. 5 illustrates the part-structure based on microscopical cell point device for mark providing according to a further embodiment of the invention
Schematic diagram；
Fig. 6 illustrates the part-structure based on microscopical cell point device for mark providing according to a further embodiment of the invention
Schematic diagram；
Fig. 7 illustrates the microscopical structural representation providing according to a further embodiment of the invention；
Fig. 8 illustrates that provide according to embodiments of the present invention does bid based on microscopical cell point device for mark on microscope slide
The schematic diagram of note；And
Fig. 9 (A)-Fig. 9 (D) is respectively and is marked based on microscopical cell point device for mark using what the present invention provided
The schematic diagram of target cell.
Specific embodiment
Describe various exemplary embodiments, feature and the aspect of the present invention below with reference to accompanying drawing in detail.Identical in accompanying drawing
Reference represent the same or analogous element of function.Although the various aspects of embodiment shown in the drawings, remove
Non-specifically points out it is not necessary to accompanying drawing drawn to scale.
Special word " exemplary " means " as example, embodiment or illustrative " here.Here as " exemplary "
Illustrated any embodiment should not necessarily be construed as preferred or advantageous over other embodiments.
In addition, in order to better illustrate the present invention, giving numerous details in specific embodiment below.
It will be appreciated by those skilled in the art that not having some details, the present invention equally can be implemented.In some instances, for
Method well known to those skilled in the art, means, element and circuit are not described in detail, in order to highlight the purport of the present invention.
Embodiment 1
Fig. 1 illustrates the structural representation based on microscopical cell point device for mark providing according to one embodiment of the invention
Figure, as shown in figure 1, the cell point device for mark 100 that the present embodiment provides includes fixed part 1, connecting portion 2 and point mark portion 3.
Wherein, fixed part 1 is used for whole cell point device for mark 100 being fixed on microscope, due to most of microscopes
Handel on there is screw, for the ease of install, it is therefore preferred to cell point device for mark 100 is fixed on handel.Connecting portion 2
It is connected with fixed part 1, point mark portion 3 is connected with connecting portion 2, the ending vertical ground in point mark portion 3 points to microscopical smooth Lu Zhizheng, energy
Enough the target location on object stage is marked.
Wherein, fixed part 1 offers at least one pair of regulating tank 4, it is possible to use fixed part 1 is fixed on micro- by screw etc.
On mirror.Regulating tank 4 may be located on horizontal direction and/or vertical direction, to adjust whole cell point device for mark 100 micro-
Position on mirror.The shape design of fixed part 1 is not limited to the form cited by the present embodiment, can be by fixed part 1 according to microscope
Difference and do different designs, be processed into different shape and form.
Connecting portion 2 can be cuboid or cylindrical structure.Connecting portion 2 can be fixedly connected with fixed part 1, as long as ensureing
The length in connecting portion 2 and point mark portion 3 is so that point mark portion 3 end points vertically upwards the position at microscopes optical path center just.
Connecting portion 2 can also be rotatably coupled with fixed part 1, for example hinged, and when connecting portion 2 goes to suitable position, leads to
Cross pin and carry out locking such that it is able to the position in point of adjustment mark portion 3 in the horizontal direction.
Point mark portion 3 includes casting die 5 and point tender 6.Wherein casting die 5 is arranged on connecting portion 2 by elastomeric element (not shown)
The one end away from fixed part 1, being arranged on the direction of object stage on casting die 5, point tender 6 is hollow to point tender 6
Structure.Point tender 6 is detachably connected with casting die 5, thus facilitates the replacing of the point tender 6 of different size (such as length).When
After pigment is smeared in the end of point tender 6, by pressing casting die 5, point tender 6 can mark the target cell on microscope slide
Position.
The cell point device for mark that the present embodiment provides, using the screw carrying on microscope, need not change microscopical knot
Structure, it becomes possible to cell point device for mark is fixed on microscope, as long as by a center for mark portion aligming microscope light path, leads to
Cross down pressure point mark portion just target cell can be made marks, accuracy is high, save manpower.And by tune is opened up on fixed part
Section groove, convenient regulation position on microscope for the cell point device for mark.
Embodiment 2
Fig. 2 illustrates the structural representation based on microscopical cell point device for mark providing according to another embodiment of the present invention
Figure, Fig. 3 illustrates corresponding front view, and Fig. 4 illustrates corresponding top view, and as shown in figs 2-4, this cell point device for mark 200 is main
Fixed part 10 to be included, adjustment portion 20 and point mark portion 30.
Wherein, fixed part 10 is used for for whole cell point device for mark 200 being fixed on microscope.Preferably, the present embodiment
In, fixed part 10 is fixed on microscopical handel.Adjustment portion 20 is connected with fixed part 10, and adjustment portion 20 is located on object stage
Side, the width in adjustment portion 20 length in the x-direction in figure 2 and y direction in fig. 2 all can be adjusted.Point mark portion
30 are connected with adjustment portion 20, and the position of the target cell for being vertically opposite on microscope slide is marked.
Specifically, as shown in figure 5, fixed part 10 includes fixed plate 11 and connector 12.Tune is offered in fixed plate 11
Section groove 13, using nut, fixed plate 10 can be fixed on handel by regulating tank 13.Wherein, the number of regulating tank 13 is preferred
For 2, regulating tank 13 can be set to vertically or horizontal direction extends it is also possible to all arrange regulation in the two directions
Groove 13.By the regulating tank 13 with certain length is opened up on fixed plate 11, height on handel for the fixed part 10 can be adjusted
Degree, or position in the horizontal direction is that is to say, that position on microscope for the whole cell point device for mark 200 can be adjusted.
Connector 12 is used for being connected with adjustment portion 20, and connector 12 is fixedly installed on the side of fixed plate 11, can be with 11 points of fixed plate
Body is formed and fits together it is also possible to be integrally formed with fixed plate 11.The shape design of fixed part 1 is not limited to the present embodiment institute
Fixed part 1 can be done different designs, be processed into different shape and form according to microscopical difference by the form enumerated.
Fixed part 10 can be fixedly connected and can also be rotatably coupled with adjustment portion 20, for example hinged.In the present embodiment
In, connector 12 can include parallel and symmetrical two grip block 121, has recess 122 between two grip blocks 121, and two
On individual grip block, 121 offer the first hole (not shown) respectively, and two the first holes are mutually corresponding.
As shown in Fig. 2～Fig. 5, adjustment portion 20 includes the first regulating part 21 and the second regulating part 22.Specifically, the first tune
One end of section part 21 is protuberance 211, and the width of the recess 122 on the width of protuberance 211 and connector 12 is adapted, and this protuberance
The position corresponding to the first hole on 211 offers the second hole, thus being capable of protuberance 211 and recess 122 by nut 123
Hinged, that is, it is capable of being rotatably connected of fixed part 10 and adjustment portion 20.Additionally, corresponding position on protuberance 211 and recess 122
Put and be additionally provided with corresponding 3rd hole 212, when adjustment cell point device for mark 200 makes target on invocation point mark portion 30 be aligned microscope slide thin
After the position of born of the same parents, pin is inserted in the 3rd hole 212, can locking fixed part 10 and adjustment portion 20, be allowed to be no longer able to turn,
It is easy to a mark portion 30 firmly to make marks.
Second regulating part 22 and the mobilizable in the longitudinal direction connection of the first regulating part 21, for example, the second regulating part 22
Can be with the first regulating part 21 relative motion in the longitudinal direction, so that adjustment portion 20 length in the longitudinal direction can
Adjust, namely make cell point device for mark 200 adjustable length in the longitudinal direction.
Specifically, in the present embodiment, the side of the first regulating part 21 has slide rail 23, and the side of the second regulating part 22 sets
It is equipped with slide block 24, slided in slide rail 23 by slide block 24, the length of adjustment portion 20 can be adjusted.On slide block 24, there is securing member
25, for fastening to slide block 24 when slide block 24 slides into suitable position.Preferably, slide rail 23 is provided with two, each
Two slide blocks 24 are set in slide rail 23.Only arranging a slide rail 23 for simplification device can also.Additionally, securing member 25 can be pin
Nail.
Further, the one or both ends of slide rail 23 have block piece 26, for stopping that slide block 24 skids off slide rail 23, this resistance
Block piece 26 can be fixed on the first regulating part 21 it is also possible to be integrally formed with the first regulating part 21.On block piece 26 also
Setting finite place piece 27, to adjust the position that slide block 24 can arrive in slide rail 23.Locating part 27 in the present embodiment is concrete
Can be screw 29, stretch out the length of block piece 26 by adjusting screw 29, being capable of movement in slide rail 23 for the adjusting slider 24
Scope, the quantity of screw 29 and position are all adapted with slide rail 23.
As shown in fig. 6, further, the width distance between the second regulating part 22 and the first regulating part 21 is adjustable.Specifically
Ground, slide block 24 is fixed on slider carrier 28, and slider carrier 28 is arranged with the second regulating part 22 split and mutual by screw 29
Connect, stretch out the length of the second regulating part 22 by adjusting screw 29, can adjust slider carrier 28 and the second regulating part 22 it
Between distance, thus realize adjust cell point device for mark 200 width.It is illustrated in Fig. 6 taking 4 screws as a example, true
Upper 3 screws can also realize the present invention.
As shown in fig. 6, point mark portion 30 specifically includes casting die 31 and point tender 32.Wherein, in the end of the second regulating part 22
Portion is provided with elastomeric element (not shown), and one end of casting die 31 is connected with elastomeric element.Point tender 32 is arranged on casting die 31, hangs down
Straight is hollow structure in the direction of object stage, and the external diameter of the present embodiment midpoint tender 32 can be in 1.5mm, with subsequent technique
The external diameter of drill bit matches.Press casting die 31 by pressing casting die 31 or by settings button 33, dynamic point tender 32 can be carried
Move straight down, the position of the target cell being placed in point on the microscope slide of microscopes optical path center is marked.
The cell point device for mark that the present embodiment provides, using the screw carrying on microscope, need not change microscopical knot
Structure it becomes possible to cell point device for mark is fixed on microscope, as long as by a center for mark portion aligming microscope light path, and
The all parts of cell point device for mark are fixed, just target cell can be made marks by lower pressure point mark portion, accuracy
Height, saves manpower.And by opening up regulating tank on fixed part, can conveniently adjust cell point device for mark on microscope
Position, in addition the length and width of adjustment portion can adjust, so that this cell point device for mark can be applied to different rule
On the microscope of lattice.It should be noted that, although taking slide block, hinged mode being as a example illustrated in the present embodiment, ability
Field technique personnel are it is understood that the frame for movement such as gear drive, pivot may be used to realize the present invention.
Embodiment 3
Present embodiments provide a kind of microscope (not shown), including the cell point device for mark 100 in above-described embodiment 1.
Embodiment 4
As shown in fig. 7, present embodiments providing a kind of microscope 300, including the cell point device for mark in above-described embodiment 2
200, this cell point device for mark 200 is arranged on the handel 301 of microscope 300.The present embodiment target cell can be for carrying green
Fluorescence protein gene virus infection cell, correspondingly microscope 300 can be specially fluorescence microscope, thus pass through microscope
300 ultraviolet excites can clearly observe fluorescent target cell.
The process using the cell point device for mark 200 that the present invention provides, target cell being marked and observing is concrete such as
Under：Microscope slide 302 is placed on the object stage 303 of microscope 300, adjustment point mark portion 32 makes it be pointing exactly to microscope 300
The position of light Lu Zhizheng, the position of adjustment microscope slide 302 is so that target cell is located at the central region region of microscope 300, so
The position pressing the button 33 pairs of target cells afterwards is marked.As shown in figure 8, target cell is corresponded on microscope slide 302
Position has a circle, is the labelling that cell point device for mark 200 is done.Fig. 9 (A) and Fig. 9 (B) is respectively in microscope 300
Target cell that is lower and seeing under visible light, then carries out ultrathin section and observation, can easily look for this target cell
To intracellular contained a large amount of virions, wherein Fig. 9 (C) shows the target cell after amplification, and Fig. 9 (D) shows target
The virus comprising in cell.
The above, the only specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, and any
Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, all should contain
Cover within protection scope of the present invention.Therefore, protection scope of the present invention should be defined by described scope of the claims.
Claims (10)
1. one kind is based on microscopical cell point device for mark it is characterised in that including：
Fixed part, is used for being fixed on microscopical handel；
Connecting portion, is connected with described fixed part；And
Point mark portion, is connected with described connecting portion, and the ending vertical ground in described point mark portion points to described microscopical smooth Lu Zhizheng, uses
In being marked to the target location on object stage；
Described point mark portion includes：
Casting die, is arranged on one end away from described fixed part of described connecting portion by elastomeric element；And
Point tender, is arranged on described casting die with the direction perpendicular to described object stage, is hollow structure；
Described tender is detachably connected with described casting die.
2. according to claim 1 based on microscopical cell point device for mark it is characterised in that opening up on described fixed part
There is at least one pair of regulating tank, described regulating tank is located on horizontal direction and/or vertical direction.
3. a kind of microscope it is characterised in that include claim 1 or 2 described in based on microscopical cell point device for mark.
4. one kind is based on microscopical cell point device for mark it is characterised in that including：
Fixed part, is used for being fixed on microscopical handel；
Adjustment portion, is connected with described fixed part, and the length and width of described adjustment portion can be adjusted；And
Point mark portion, is connected with described fixed part, and the ending vertical ground in described point mark portion points to described microscopical smooth Lu Zhizheng, uses
In being marked to the target location on object stage；
Described point mark portion includes：
Casting die, is arranged on one end away from described fixed part of described adjustment portion by elastomeric element；And
Point tender, is arranged on described casting die with the direction perpendicular to described object stage, is hollow structure；
Described tender is detachably connected with described casting die.
5. according to claim 4 based on microscopical cell point device for mark it is characterised in that described fixed part includes：
Fixed plate, described fixed plate offers at least one pair of regulating tank, described regulating tank be located at horizontal direction and/or vertically side
Upwards；And
Connector, is rotatably coupled in the horizontal direction with described adjustment portion.
6. according to claim 5 based on microscopical cell point device for mark it is characterised in that described connector with described
The part that adjustment portion connects carries out locking by pin.
7. according to claim 4 based on microscopical cell point device for mark it is characterised in that described adjustment portion includes：
First regulating part, described first regulating part is provided with slide rail on the length direction along described adjustment portion；And
Second regulating part, described second regulating part is provided with slide block on the length direction along described adjustment portion, and described slide block exists
Slide in described slide rail, described slide block is provided with securing member.
8. according to claim 7 based on microscopical cell point device for mark it is characterised in that described slide block is arranged on cunning
On block carrier, described slider carrier is connected with described second regulating part by screw.
9. according to claim 7 based on microscopical cell point device for mark it is characterised in that the end of described slide rail sets
It is equipped with block piece and locating part.
10. a kind of microscope it is characterised in that include any one of claim 4-9 described in based on microscopical cell point mark
Device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410498599.6A CN104198255B (en) | 2014-09-25 | 2014-09-25 | One kind is based on microscopical cell point device for mark and microscope |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410498599.6A CN104198255B (en) | 2014-09-25 | 2014-09-25 | One kind is based on microscopical cell point device for mark and microscope |
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| CN104198255A CN104198255A (en) | 2014-12-10 |
| CN104198255B true CN104198255B (en) | 2017-03-08 |
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| CN201410498599.6A Expired - Fee Related CN104198255B (en) | 2014-09-25 | 2014-09-25 | One kind is based on microscopical cell point device for mark and microscope |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105891216B (en) * | 2016-04-12 | 2018-10-02 | 京东方科技集团股份有限公司 | Microscope labelling apparatus |
| CN106707481A (en) * | 2017-01-13 | 2017-05-24 | 宁波舜宇仪器有限公司 | Marking device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690521A (en) * | 1986-01-24 | 1987-09-01 | Geno Saccomanno | Microscope slide marking device and method |
| US5715082A (en) * | 1995-10-19 | 1998-02-03 | Geno Saccomanno | Microscope attached slide dotting device |
| US6601488B1 (en) * | 1999-05-07 | 2003-08-05 | University Of Kentucky Research Foundation | Cutter assembly for a microscope and related method |
| CN204085982U (en) * | 2014-09-25 | 2015-01-07 | 中国疾病预防控制中心病毒病预防控制所 | A kind of based on microscopical cell point device for mark and microscope |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5653414Y2 (en) * | 1978-05-16 | 1981-12-12 |
-
2014
- 2014-09-25 CN CN201410498599.6A patent/CN104198255B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690521A (en) * | 1986-01-24 | 1987-09-01 | Geno Saccomanno | Microscope slide marking device and method |
| US5715082A (en) * | 1995-10-19 | 1998-02-03 | Geno Saccomanno | Microscope attached slide dotting device |
| US6601488B1 (en) * | 1999-05-07 | 2003-08-05 | University Of Kentucky Research Foundation | Cutter assembly for a microscope and related method |
| CN204085982U (en) * | 2014-09-25 | 2015-01-07 | 中国疾病预防控制中心病毒病预防控制所 | A kind of based on microscopical cell point device for mark and microscope |
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| Publication number | Publication date |
|---|---|
| CN104198255A (en) | 2014-12-10 |
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