CN104198255A - Cell marking device based on microscope and microscope - Google Patents

Cell marking device based on microscope and microscope Download PDF

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Publication number
CN104198255A
CN104198255A CN201410498599.6A CN201410498599A CN104198255A CN 104198255 A CN104198255 A CN 104198255A CN 201410498599 A CN201410498599 A CN 201410498599A CN 104198255 A CN104198255 A CN 104198255A
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China
Prior art keywords
mark
point device
microscope
microscopical
cell
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Granted
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CN201410498599.6A
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Chinese (zh)
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CN104198255B (en
Inventor
宋敬东
屈建国
洪涛
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National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention
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National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention
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Priority to CN201410498599.6A priority Critical patent/CN104198255B/en
Publication of CN104198255A publication Critical patent/CN104198255A/en
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Publication of CN104198255B publication Critical patent/CN104198255B/en
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Abstract

The invention relates to a cell marking device based on a microscope and a microscope. The cell marking device comprises a fixed part fixed on the microscope, a connection part connected with the fixed part, and a marking part connected with the connection part, wherein the tail end of the marking part perpendicularly points to the center of a light path of the microscope and is used for marking a target position on an objective table. The microscope comprises the cell marking device. The cell marking device provided by the embodiment of the invention can be fixed on the microscope; a target cell can be marked by only aligning the marking part to the center position of the light path of the microscope and pressing down the marking part, so that the accuracy is high, and the labor is saved; furthermore, an adjustment slot is formed in the fixed part, so that the position of the cell marking device on the microscope can be convenient to adjust.

Description

A kind of based on microscopical cell point device for mark and microscope
Technical field
The present invention relates to microscopy field, relate in particular to a kind of based on microscopical cell point device for mark and comprise the microscope of this cell point device for mark.
Background technology
Transmission electron microscope (Transmission electron microscope, TEM) technology is detect and study viral important means, is one of one preferred technique of the unknown cause of disease of diagnosis and identification of organism attack of terrorism cause of disease.Ultramicrotomy is the important technology that forms biological TEM technical system.Generally, adhere-wall culture cell ultra-thin section sample making course needs following steps to complete: first directly with cell sleaker, scrape de-cell or make cell detachment cultivate interface by trypsinization, again the cell of de-wall is carried out centrifugally making it be gathered into agglomerate, then cell mass is carried out aldehydes and osmium tetroxide two fixing, gradient ethanol (or epoxypropane or acetone) dehydration, resin infiltration, embedding, polymerizations, repaiies the handling procedures such as piece and section.The processing such as scraping and enzymic digestion can cause cell ultrastructure to change, thereby is difficult to reflect the true nature state of attached cell.Above-mentioned processing has made cell detachment fixed position, through centrifugal gathering, form agglomerate, cell is randomly dispersed in cell mass, after above-mentioned processing, in section, there are a lot of cells, be difficult to realize by the viewed same cell of transmission electron microscope observation optical microscope, greatly reduce the detection efficiency of transmission electron microscope to cell ultra-thin section.
In order to observe the viewed target cell of optical microscope under transmission electron microscope, applicant's a patent previous has been set up locating super-thin microtomy (patent < < locating super-thin dicing method > > for the viral sick cell of infection that application number is 201310470347.8).When application locating super-thin microtomy, position for convenience target-marking cell before section, conventionally in manual mode, mark is carried out in target cell position, concrete grammar is in the microscopic examination visual field, to use the position of marking pen mark target cell on microslide.Because the micron-sized cell position of manual markings is larger for manual operations difficulty, thereby operator is had to higher requirement, for example require operator to there is good arm steady qualitative, in labeling process, can not there is arm shake, and need operator to possess good stereoscopic sensation under microscope etc.Once a little shake occurs hand, the position of mark position wide cell will be caused.In addition, generally thicker for the nib of the marking pen of mark, the size in labeling dye region is much larger than target cell region, and this also causes mark position inaccurate.As mentioned above, craft is carried out mark to cell position mode accuracy and efficiency are all lower.
Summary of the invention
technical matters
In view of this, the technical problem to be solved in the present invention is, how precise and high efficiency mark is carried out in the position of the target cell on microslide, to facilitate the follow-up positioning searching for target cell, isolated cell and to carry out the ultra-thin section of target cell.
solution
In order to solve the problems of the technologies described above, according to one embodiment of the invention, provide a kind of based on microscopical cell point device for mark, comprising:
Fixed part, for being fixed on microscope;
Connecting portion, is connected with described fixed part; And
Point mark portion, is connected with described connecting portion, and the end of described some mark portion vertically points to described microscopical light path center, for the target location on objective table, carries out mark.
For above-mentioned, based on microscopical cell point device for mark, in a kind of possible implementation, offer at least one pair of regulating tank on described fixed part, described regulating tank is positioned on horizontal direction and/or vertical direction.
For above-mentioned, based on microscopical cell point device for mark, in a kind of possible implementation, described some mark portion comprises:
Casting die, is arranged on one end away from described fixed part of described connecting portion by elastomeric element; And
Point tender, is arranged on described casting die with the direction perpendicular to described objective table, is hollow structure.
In order to solve the problems of the technologies described above, according to another embodiment of the present invention, also provide a kind of microscope, comprise above-mentioned based on microscopical cell point device for mark.
In order to solve the problems of the technologies described above, according to still another embodiment of the invention, also provide a kind of based on microscopical cell point device for mark, comprising:
Fixed part, for being fixed on microscope;
Adjusting portion, is connected with described fixed part, and the length of described adjusting portion and width can regulate; And
Point mark portion, is connected with described fixed part, and the end of described some mark portion vertically points to described microscopical light path center, for the target location on objective table, carries out mark.
For above-mentioned, based on microscopical cell point device for mark, in a kind of possible implementation, described fixed part comprises:
Fixed head, offers at least one pair of regulating tank on described fixed head, described regulating tank is positioned on horizontal direction and/or vertical direction; And
Web member, is connected in the horizontal direction rotationally with described adjusting portion.
For above-mentioned, based on microscopical cell point device for mark, in a kind of possible implementation, the part that described web member is connected with described adjusting portion is carried out locking by pin.
For above-mentioned, based on microscopical cell point device for mark, in a kind of possible implementation, described adjusting portion comprises:
The first regulating part, described the first regulating part is provided with slide rail on the length direction along described adjusting portion; And
The second regulating part, described the second regulating part is provided with slide block on the length direction along described adjusting portion, and described slide block slides in described slide rail, on described slide block, is provided with securing member.
For above-mentioned, based on microscopical cell point device for mark, in a kind of possible implementation, described slide block is arranged on slide block carrier, and described slide block carrier is connected with described the second regulating part by screw.
For above-mentioned, based on microscopical cell point device for mark, in a kind of possible implementation, the end of described slide rail is provided with block piece and locating part.
For above-mentioned, based on microscopical cell point device for mark, in a kind of possible implementation, described some mark portion comprises:
Casting die, is arranged on one end away from described fixed part of described adjusting portion by elastomeric element; And
Point tender, is arranged on described casting die with the direction perpendicular to described objective table, is hollow structure.
In order to solve the problems of the technologies described above, according to an embodiment more of the present invention, provide a kind of microscope, comprise above-mentioned based on microscopical cell point device for mark.
beneficial effect
The present embodiment provide based on microscopical cell point device for mark, can be fixed on microscope, as long as by a center for mark portion aligming microscope light path, by lower pressure point mark portion, just can make marks to target cell, accuracy is high, saving manpower.And by offer regulating tank on fixed part, the convenient position of cell point device for mark on microscope that regulate.Further, because length and the width of adjusting portion can both regulate, thereby this cell point device for mark can be applied on the microscope of different size.Cell point device for mark provided by the invention, can replace manually precise marking easily being realized in the position of micron order cell, and without specific (special) requirements, simple to operate to operator, degree of accuracy is high, reproducible, is easy to promote.
According to below with reference to accompanying drawing to detailed description of illustrative embodiments, it is clear that further feature of the present invention and aspect will become.
Accompanying drawing explanation
The accompanying drawing that is included in instructions and forms a part for instructions shows exemplary embodiment of the present invention, feature and aspect together with instructions, and for explaining principle of the present invention.
The structural representation based on microscopical cell point device for mark providing according to one embodiment of the invention is provided Fig. 1;
The structural representation based on microscopical cell point device for mark providing is according to a further embodiment of the invention provided Fig. 2;
The front view based on microscopical cell point device for mark providing is according to a further embodiment of the invention provided Fig. 3;
The vertical view based on microscopical cell point device for mark providing is according to a further embodiment of the invention provided Fig. 4;
The part-structure schematic diagram based on microscopical cell point device for mark providing is according to a further embodiment of the invention provided Fig. 5;
The part-structure schematic diagram based on microscopical cell point device for mark providing is according to a further embodiment of the invention provided Fig. 6;
The microscopical structural representation providing is according to a further embodiment of the invention provided Fig. 7;
The schematic diagram making a mark on microslide based on microscopical cell point device for mark providing according to the embodiment of the present invention is provided Fig. 8; And
Fig. 9 (A)-Fig. 9 (D) is respectively the schematic diagram that adopts the target cell marking based on microscopical cell point device for mark provided by the invention.
Embodiment
Below with reference to accompanying drawing, describe various exemplary embodiments of the present invention, feature and aspect in detail.The identical same or analogous element of Reference numeral presentation function in accompanying drawing.Although the various aspects of embodiment shown in the drawings, unless otherwise indicated, needn't draw accompanying drawing in proportion.
Here special-purpose word " exemplary " means " as example, embodiment or illustrative ".Here as " exemplary " illustrated any embodiment, needn't be interpreted as being better than or being better than other embodiment.
In addition, for better explanation the present invention, in embodiment below, provided numerous details.It will be appreciated by those skilled in the art that and there is no some detail, the present invention can implement equally.In some instances, the method for knowing for those skilled in the art, means, element and circuit are not described in detail, so that highlight purport of the present invention.
embodiment 1
The structural representation based on microscopical cell point device for mark providing according to one embodiment of the invention is provided Fig. 1, and as shown in Figure 1, the cell point device for mark 100 that the present embodiment provides comprises fixed part 1, connecting portion 2 and some mark portion 3.
Wherein, fixed part 1, for whole cell point device for mark 100 is fixed on to microscope, owing to having screw on most of microscopical handels, for the ease of installing, is therefore preferably put device for mark 100 by cell and is fixed on handel.Connecting portion 2 is connected with fixed part 1, and some mark portion 3 is connected with connecting portion 2, and the end of some mark portion 3 vertically points to microscopical light path center, can carry out mark to the target location on objective table.
Wherein, on fixed part 1, offer at least one pair of regulating tank 4, can use screw etc. that fixed part 1 is fixed on microscope.Regulating tank 4 can be positioned on horizontal direction and/or vertical direction, to regulate the position of whole cell point device for mark 100 on microscope.The shape structure of fixed part 1 is not limited to the cited form of the present embodiment, fixed part 1 can be done to different designs according to microscopical difference, is processed into difformity and form.
Connecting portion 2 can be rectangular parallelepiped or cylindrical structure.Connecting portion 2 can be fixedly connected with fixed part 1, as long as guarantee the length of connecting portion 2 and some mark portion 3, makes invocation point mark portion 3 ends just vertically point to the position at microscope light path center.Connecting portion 2 also can be connected rotationally with fixed part 1, for example hinged, and when connecting portion 2 forwards suitable position to, by pin, carries out locking, thus the position of point of adjustment mark portion 3 in the horizontal direction.
Point mark portion 3 comprises casting die 5 and some tender 6.Wherein casting die 5 is arranged on one end away from fixed part 1 of connecting portion 2 by elastomeric element (not shown), and some tender 6 is arranged on casting die 5 in the direction perpendicular to objective table, and some tender 6 is hollow structure.Point tender 6 removably connects with casting die 5, facilitates thus the replacing of the some tender 6 of different size (for example length).When after the end of a tender 6 is smeared pigment, by pressing casting die 5, some tender 6 can mark the position of the target cell on microslide.
The cell point device for mark that the present embodiment provides, utilize the screw carrying on microscope, without changing microscopical structure, just cell can be put to device for mark is fixed on microscope, as long as by a center for mark portion aligming microscope light path, by lower pressure point mark portion, just can make marks to target cell, accuracy is high, saves manpower.And by offer regulating tank on fixed part, the convenient position of cell point device for mark on microscope that regulate.
embodiment 2
The structural representation based on microscopical cell point device for mark providing according to another embodiment of the present invention is provided Fig. 2, Fig. 3 illustrates corresponding front view, Fig. 4 illustrates corresponding vertical view, as shown in Fig. 2-Fig. 4, this cell point device for mark 200 mainly comprises fixed part 10, adjusting portion 20 and some mark portion 30.
Wherein, fixed part 10 is for being fixed on microscope by whole cell point device for mark 200.Preferably, in the present embodiment, fixed part 10 is fixed on microscopical handel.Adjusting portion 20 is connected with fixed part 10, and adjusting portion 20 is positioned at objective table top, and the length in the x direction of adjusting portion 20 in Fig. 2 and the width in the y direction in Fig. 2 all can regulate.Point mark portion 30 is connected with adjusting portion 20, for being vertically opposite to the position of the target cell on microslide, carries out mark.
Particularly, as shown in Figure 5, fixed part 10 comprises fixed head 11 and web member 12.On fixed head 11, offer regulating tank 13, by regulating tank 13, can use nut that fixed head 10 is fixed on handel.Wherein, the number of regulating tank 13 is preferably 2, regulating tank 13 can be set to vertically or horizontal direction extension, also regulating tank 13 can be all set on both direction.By offer the regulating tank 13 with certain length on fixed head 11, can regulate the height of fixed part 10 on handel, or position in the horizontal direction, that is to say and can regulate the position of whole cell point device for mark 200 on microscope.Web member 12 is for being connected with adjusting portion 20, and web member 12 is fixedly installed on a side of fixed head 11, can form and fit together with fixed head 11 splits, also can be integrally formed with fixed head 11.The shape structure of fixed part 1 is not limited to the cited form of the present embodiment, fixed part 1 can be done to different designs according to microscopical difference, is processed into difformity and form.
Fixed part 10 can be fixedly connected with also and can be connected rotationally with adjusting portion 20, for example hinged.In the present embodiment, web member 12 can comprise that between parallel and symmetrical 121, two grip blocks 121 of two grip blocks, having on 122, two grip blocks of recess 121 offers respectively the first hole (not shown), and two the first holes are mutually corresponding.
As shown in Fig. 2~Fig. 5, adjusting portion 20 comprises the first regulating part 21 and the second regulating part 22.Particularly, one end of the first regulating part 21 is protuberance 211, the width of the recess 122 on the width of protuberance 211 and web member 12 adapts, and the position corresponding to the first hole on this protuberance 211 offers the second hole, thereby by nut 123, can realize the hinged of protuberance 211 and recess 122, can realize being rotatably connected of fixed part 10 and adjusting portion 20.In addition, on protuberance 211 and recess 122, corresponding position is also provided with the 3rd corresponding hole 212, after adjustment cell point device for mark 200 makes the position of target cell on invocation point mark portion 30 aligning microslides, pin is inserted in the 3rd hole 212, can locking fixed part 10 with adjusting portion 20, make it to rotate again, be convenient to a mark portion 30 and firmly make marks.
The second regulating part 22 and the first regulating part 21 be mobilizable connection in the longitudinal direction, for example, the second regulating part 22 can with the first regulating part 21 relative motion in the longitudinal direction, thereby make adjusting portion 20 length in the longitudinal direction adjustable, also make cell point device for mark 200 length in the longitudinal direction adjustable.
Particularly, in the present embodiment, the side that the side of the first regulating part 21 has slide rail 23, the second regulating parts 22 is provided with slide block 24, by slide block 24, in slide rail 23, slides, and can adjust the length of adjusting portion 20.On slide block 24, there is securing member 25, for carrying out fastening to slide block 24 when slide block 24 slides into suitable position.Preferably, slide rail 23 is provided with two, and two slide blocks 24 are set in each slide rail 23.For simplification device, that a slide rail 23 is only set is also passable.In addition, securing member 25 can be pin.
Further, the one or both ends of slide rail 23 have block piece 26, and for stopping that slide block 24 skids off slide rail 23, this block piece 26 can be fixed on the first regulating part 21, also can be integrally formed with the first regulating part 21.On block piece 26, be also provided with locating part 27, the position that can arrive to adjust slide block 24 in slide rail 23.Locating part 27 in the present embodiment is specifically as follows screw 29, stretches out the length of block piece 26 by set screw 29, can the moving range of adjusting slider 24 in slide rail 23, and the quantity of screw 29 and position all adapt with slide rail 23.
As shown in Figure 6, further, the width distance between the second regulating part 22 and the first regulating part 21 is adjustable.Particularly, slide block 24 is fixed on slide block carrier 28, slide block carrier 28 and the second regulating part 22 split settings and interconnect by screw 29, by set screw 29, stretch out the length of the second regulating part 22, can adjust the distance between slide block carrier 28 and the second regulating part 22, thereby realize the width of adjusting cell point device for mark 200.4 screws of take in Fig. 6 are illustrated as example, and in fact 3 screws also can be realized the present invention.
As shown in Figure 6, some mark portion 30 specifically comprises casting die 31 and some tender 32.Wherein, the inner end portion of the second regulating part 22 is provided with elastomeric element (not shown), and one end of casting die 31 is connected with elastomeric element.Point tender 32 is arranged on casting die 31, perpendicular to the direction of objective table, is hollow structure, and the external diameter of the present embodiment mid point tender 32 can be 1.5mm, matches with the external diameter of drill bit in subsequent technique.By pressing casting die 31 or pressing casting die 31 by button 33 is set, can drive a tender 32 to move straight down, mark is carried out in the position that is placed on the target cell on the microslide of microscope light path center in point.
The cell point device for mark that the present embodiment provides, utilize the screw carrying on microscope, without changing microscopical structure, just cell can be put to device for mark is fixed on microscope, as long as by a center for mark portion aligming microscope light path, and all parts that cell is put device for mark is fixed, by lower pressure point mark portion, just can makes marks to target cell, accuracy is high, saves manpower.And by offer regulating tank on fixed part, can conveniently regulate the position of cell point device for mark on microscope, the length of adjusting portion and width can both regulate in addition, thereby this cell point device for mark can be applied on the microscope of different size.It should be noted that, although take slide block, hinged mode in the present embodiment, be illustrated as example, those skilled in the art can understand, and the physical constructions such as gear drive, pivotable may be used to realize the present invention.
embodiment 3
The present embodiment provides a kind of microscope (not shown), comprises the cell point device for mark 100 in above-described embodiment 1.
embodiment 4
As shown in Figure 7, the present embodiment provides a kind of microscope 300, comprises the cell point device for mark 200 in above-described embodiment 2, and this cell point device for mark 200 is arranged on the handel 301 of microscope 300.The present embodiment target cell can be the cell that Carrying Green Fluorescent Protein gene viruses infects, and correspondingly microscope 300 can be specially fluorescent microscope, thereby can clearly observe fluorescent target cell by the ultraviolet ray excited of microscope 300.
The process that adopts 200 pairs of target cells of cell point device for mark provided by the invention to carry out mark and observation is specific as follows: microslide 302 is placed on the objective table 303 of microscope 300, adjusting some mark portion 32 makes it just point to the position at the light path center of microscope 300, adjust the position of microslide 302, make target cell be positioned at the central area, the visual field of microscope 300, mark is carried out in the position that then presses the button 33 pairs of target cells.As shown in Figure 8, the position corresponding to target cell on microslide 302 has a circle, is the mark that cell point device for mark 200 is done.Fig. 9 (A) and Fig. 9 (B) are respectively at microscope 300 times and the target cell seen under visible ray, then this target cell is carried out to ultra-thin section and observation, can easily find contained a large amount of virions in cell, wherein Fig. 9 (C) shows the target cell after amplification, and Fig. 9 (D) shows the virus comprising in target cell.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited to this, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; can expect easily changing or replacing, within all should being encompassed in protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of described claim.

Claims (12)

1. based on a microscopical cell point device for mark, it is characterized in that, comprising:
Fixed part, for being fixed on microscope;
Connecting portion, is connected with described fixed part; And
Point mark portion, is connected with described connecting portion, and the end of described some mark portion vertically points to described microscopical light path center, for the target location on objective table, carries out mark.
2. according to claim 1ly based on microscopical cell point device for mark, it is characterized in that, on described fixed part, offer at least one pair of regulating tank, described regulating tank is positioned on horizontal direction and/or vertical direction.
3. according to claim 1 and 2ly based on microscopical cell point device for mark, it is characterized in that, described some mark portion comprises:
Casting die, is arranged on one end away from described fixed part of described connecting portion by elastomeric element; And
Point tender, is arranged on described casting die with the direction perpendicular to described objective table, is hollow structure.
4. a microscope, is characterized in that, comprise described in claim 1-3 any one based on microscopical cell point device for mark.
5. based on a microscopical cell point device for mark, it is characterized in that, comprising:
Fixed part, for being fixed on microscope;
Adjusting portion, is connected with described fixed part, and the length of described adjusting portion and width can regulate; And
Point mark portion, is connected with described fixed part, and the end of described some mark portion vertically points to described microscopical light path center, for the target location on objective table, carries out mark.
6. according to claim 5ly based on microscopical cell point device for mark, it is characterized in that, described fixed part comprises:
Fixed head, offers at least one pair of regulating tank on described fixed head, described regulating tank is positioned on horizontal direction and/or vertical direction; And
Web member, is connected in the horizontal direction rotationally with described adjusting portion.
7. according to claim 6ly based on microscopical cell point device for mark, it is characterized in that, the part that described web member is connected with described adjusting portion is carried out locking by pin.
8. according to claim 5ly based on microscopical cell point device for mark, it is characterized in that, described adjusting portion comprises:
The first regulating part, described the first regulating part is provided with slide rail on the length direction along described adjusting portion; And
The second regulating part, described the second regulating part is provided with slide block on the length direction along described adjusting portion, and described slide block slides in described slide rail, on described slide block, is provided with securing member.
9. according to claim 8ly based on microscopical cell point device for mark, it is characterized in that, described slide block is arranged on slide block carrier, and described slide block carrier is connected with described the second regulating part by screw.
10. according to claim 8ly based on microscopical cell point device for mark, it is characterized in that, the end of described slide rail is provided with block piece and locating part.
11. according to described in claim 5-10 any one based on microscopical cell point device for mark, it is characterized in that, described some mark portion comprises:
Casting die, is arranged on one end away from described fixed part of described adjusting portion by elastomeric element; And
Point tender, is arranged on described casting die with the direction perpendicular to described objective table, is hollow structure.
12. 1 kinds of microscopes, is characterized in that, comprise described in claim 5-11 any one based on microscopical cell point device for mark.
CN201410498599.6A 2014-09-25 2014-09-25 One kind is based on microscopical cell point device for mark and microscope Expired - Fee Related CN104198255B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105891216A (en) * 2016-04-12 2016-08-24 京东方科技集团股份有限公司 Marking device for microscope
CN106707481A (en) * 2017-01-13 2017-05-24 宁波舜宇仪器有限公司 Marking device

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US4690521A (en) * 1986-01-24 1987-09-01 Geno Saccomanno Microscope slide marking device and method
US5715082A (en) * 1995-10-19 1998-02-03 Geno Saccomanno Microscope attached slide dotting device
US6601488B1 (en) * 1999-05-07 2003-08-05 University Of Kentucky Research Foundation Cutter assembly for a microscope and related method
CN204085982U (en) * 2014-09-25 2015-01-07 中国疾病预防控制中心病毒病预防控制所 A kind of based on microscopical cell point device for mark and microscope

Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
JPS5653414Y2 (en) * 1978-05-16 1981-12-12
US4690521A (en) * 1986-01-24 1987-09-01 Geno Saccomanno Microscope slide marking device and method
US5715082A (en) * 1995-10-19 1998-02-03 Geno Saccomanno Microscope attached slide dotting device
US6601488B1 (en) * 1999-05-07 2003-08-05 University Of Kentucky Research Foundation Cutter assembly for a microscope and related method
CN204085982U (en) * 2014-09-25 2015-01-07 中国疾病预防控制中心病毒病预防控制所 A kind of based on microscopical cell point device for mark and microscope

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105891216A (en) * 2016-04-12 2016-08-24 京东方科技集团股份有限公司 Marking device for microscope
CN105891216B (en) * 2016-04-12 2018-10-02 京东方科技集团股份有限公司 Microscope labelling apparatus
CN106707481A (en) * 2017-01-13 2017-05-24 宁波舜宇仪器有限公司 Marking device

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