CN104189572B - Treat the Chinese medicine composition and its aerosol and preparation method of chronic pharyngitis - Google Patents
Treat the Chinese medicine composition and its aerosol and preparation method of chronic pharyngitis Download PDFInfo
- Publication number
- CN104189572B CN104189572B CN201410418303.5A CN201410418303A CN104189572B CN 104189572 B CN104189572 B CN 104189572B CN 201410418303 A CN201410418303 A CN 201410418303A CN 104189572 B CN104189572 B CN 104189572B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine composition
- chronic pharyngitis
- aerosol
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a kind of Chinese medicine composition for treating chronic pharyngitis, the Chinese medicine composition is mainly prepared from by the bulk drug of Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood, radix bupleuri, the leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii, Radix Angelicae Sinensis and the Radix Astragali through constant weight number；The Chinese medicine composition has good therapeutic effect to chronic pharyngitis, and effective percentage is up to 100%, and side effect is low, is difficult repeatedly, uneasy to recur.
Description
Technical field
The invention belongs to the field of Chinese medicines, more particularly to a kind of Chinese medicine composition and its aerosol and system for treating chronic pharyngitis
Method.
Background technology
Chronic pharyngitis is a kind of common disease, frequently-occurring disease, when being apt to occur in season alternation；During morbidity, constitutional symptom is not obvious,
And based on local symptom；Common disease is pharyngeal sense of discomfort, and foreign body sensation, gargalesthesia, burning heat sensation, dry sensation or excitement may be used also
There is hypodynia sense etc.；Caused by the main lymph follicle by its secretion and hypertrophy is stimulated.
The medicine for the treatment of chronic pharyngitis is largely divided into two major classes at present, and a class is Western medicine, it is well known that Western medicine, which takes stopgap measures, not to be controlled
This, the state of an illness is easily repeatedly；Chinese medicine is low due to side effect, is had a wide range of applications in terms of chronic pharyngitis is treated.
For example, CN103830601 discloses a kind of Chinese medicine for treating chronic pharyngitis, the Chinese medicine by Sculellaria barbata, edible tulip and
The taste Chinese herbal medicine of selfheal etc. 18 is constituted；CN103735626, which is disclosed, a kind of to be made up of lotus rhizome section, white sugar and the taste medicine of menthol three
Treat the medicine of chronic pharyngitis；Chinese medicine disclosed above has certain therapeutic action to chronic pharyngitis, but effect is not notable,
Easily repeatedly, so being badly in need of providing a kind of Chinese medicine composition of effective treatment chronic pharyngitis at present.
The content of the invention
In order to solve the above-mentioned technical problem, the present invention provides a kind of Chinese medicine composition and its aerosol for treating chronic pharyngitis
And preparation method, said composition and its aerosol have good therapeutic effect to chronic pharyngitis, are difficult repeatedly, uneasy to recur, and pair is made
With low.
The present invention provides a kind of Chinese medicine composition for treating chronic pharyngitis, and the Chinese medicine composition is main by following parts by weight
Bulk drug be prepared from：
The Chinese medicine composition for the treatment chronic pharyngitis that the present invention is provided has good therapeutic effect to chronic pharyngitis, and pair is made
With low, it is difficult repeatedly, it is uneasy to recur.
Further to improve, the Chinese medicine composition is mainly prepared from by the bulk drug of following parts by weight：
Further aerosol is made in the Chinese medicine composition and additives that treat chronic pharyngitis by the present invention, wherein, Chinese medicine group
The ratio of weight and number of compound and additives is 1:0.2-0.5.
Preferably, the additives include pH adjusting agent.
Preferably, the additives also include the mixture of triethanolamine stearate and methylcellulose, wherein, three ethanol
The ratio of weight and number of amine stearate and methylcellulose is 5-7:1.
The present invention adds the mixture of triethanolamine stearate and methylcellulose in aerosol, not only plays very well
Emulsifying effectiveness；The dissolution rate of Chinese medicine composition can be improved simultaneously, Chinese medicine composition is given full play to curative effect.
In order to improve the stability of aerosol, additives of the invention also include potassium sorbate and lauryl sodium sulfate
Mixture, wherein, the ratio of weight and number of potassium sorbate and lauryl sodium sulfate is 2-3:1.
On the other hand, the present invention also provides a kind of preparation method for the Chinese medicine composition for treating chronic pharyngitis, this method bag
Include following steps：
Methods described comprises the following steps：
A. the leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii and the Radix Angelicae Sinensis for weighing recipe quantity are crushed, and are placed in seepage bucket, are added 60-80%
Effusion is collected in ethanol solution, immersion, is concentrated, and is dried, and fine powder is made；
B. Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood and the radix bupleuri of recipe quantity are weighed, water is added, 1-3h is soaked
Afterwards, decoction three times is added water, decoction liquor is collected, filtering adds absolute ethyl alcohol, stirred, stands, and collects supernatant, concentrates, is made
Mixed powder；
C. the Radix Astragali of recipe quantity is weighed, Ultramicro-powder is made in ultramicro grinding；
D. Ultramicro-powder made from mixed powder made from fine powder made from step a, step b and step c is well mixed, be made
Chinese medicine composition.
Preferably, the preparation method of Chinese medicine composition comprises the following steps：
1) leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii and the Radix Angelicae Sinensis for weighing recipe quantity are crushed, and are placed in seepage bucket, are added 75% ethanol
After solution 2500ml, immersion 72h, extract solution is collected in refluxing extraction 5h, filtering；75% ethanol solution is added into the dregs of a decoction again
2500ml, refluxing extraction 3h, collect extract solution, extract solution will merge twice, and concentrate, dry, fine powder is made；
2) Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood and the radix bupleuri of recipe quantity are weighed, 2000ml water, immersion is added
After 1h, after the boiled 10min of big fire, then 45min is cooked by slow fire；Filtering, collects first time decoction；2000ml is added into the dregs of a decoction
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect second of decoction；2000ml is added into the dregs of a decoction again
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect third time decoction；Merge three decoctions, add
3000ml absolute ethyl alcohols, stirring stands 24h, collects supernatant, and mixed powder is made in concentration；
3) Radix Astragali of recipe quantity is weighed, Ultramicro-powder is made in ultramicro grinding；
4) by step 1) made from fine powder, step 2) made from mixed powder and step 3) made from Ultramicro-powder be well mixed,
Chinese medicine composition is made.
The present invention can fully be extracted the active component in each bulk drug by the above method so that be prepared
Chinese medicine composition in the amount of active component significantly improve, the Chinese medicine composition enable fully plays drug effect.
Another aspect of the present invention additionally provides the preparation method of aerosol, and this method comprises the following steps：
A) leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii and the Radix Angelicae Sinensis for weighing recipe quantity are crushed, and are placed in seepage bucket, are added 75% ethanol
After solution 2500ml, immersion 72h, effusion is collected, it is standby；
B) Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood and the radix bupleuri of recipe quantity are weighed, 2000ml water, immersion is added
After 1h, after the boiled 10min of big fire, then 45min is cooked by slow fire；Filtering, collects first time decoction；2000ml is added into the dregs of a decoction
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect second of decoction；2000ml is added into the dregs of a decoction again
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect third time decoction；Merge three decoctions, add
3000ml absolute ethyl alcohols, stirring stands 24h, collects supernatant, reclaims ethanol to decoction 600ml, then add distilled water extremely
2500ml, is made reserve liquid；
C) Radix Astragali of recipe quantity is weighed, Ultramicro-powder is made in ultramicro grinding；
D) reserve liquid made from effusion made from step a) and step b) is merged, mixed liquor is made, add anhydrous second
Alcohol, makes alcohol content in mixed liquor reach 15%-20%, adds pH adjusting agent, and regulation pH value is 5-8；Add step c) obtained
Ultramicro-powder, is well mixed, and is made.
The Chinese medicine composition for the treatment chronic pharyngitis that the present invention is provided can prepare the medicine for treating chronic pharyngitis simultaneously.
The invention provides a kind of evident in efficacy, Chinese medicine composition of the low treatment chronic pharyngitis of side effect, it is to chronic
The effective percentage of pharyngitis has reached 100%；Obtained aerosol properties are stable, and significantly, curative effect is high for the dissolution of Chinese medicine composition；There is provided
Preparation method the active component in each bulk drug can be efficiently extracted out.
Embodiment
Embodiment 1
A kind of Chinese medicine composition for treating chronic pharyngitis, the main bulk drug system by following parts by weight of the Chinese medicine composition
It is standby to form：
Preparation method：
1) leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii and the Radix Angelicae Sinensis for weighing recipe quantity are crushed, and are placed in seepage bucket, are added 75% ethanol
After solution 2500ml, immersion 72h, extract solution is collected in refluxing extraction 5h, filtering；75% ethanol solution is added into the dregs of a decoction again
2500ml, refluxing extraction 3h, collect extract solution, extract solution will merge twice, and concentrate, dry, fine powder is made；
2) Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood and the radix bupleuri of recipe quantity are weighed, 2000ml water, immersion is added
After 1h, after the boiled 10min of big fire, then 45min is cooked by slow fire；Filtering, collects first time decoction；2000ml is added into the dregs of a decoction
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect second of decoction；2000ml is added into the dregs of a decoction again
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect third time decoction；Merge three decoctions, add
3000ml absolute ethyl alcohols, stirring stands 24h, collects supernatant, and mixed powder is made in concentration；
3) Radix Astragali of recipe quantity is weighed, Ultramicro-powder is made in ultramicro grinding；
4) by step 1) made from fine powder, step 2) made from mixed powder and step 3) made from Ultramicro-powder be well mixed,
Chinese medicine composition is made.
Embodiment 2
A kind of Chinese medicine composition for treating chronic pharyngitis, the Chinese medicine composition by following parts by weight bulk drug prepare and
Into：
Preparation method：
A. the leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii and the Radix Angelicae Sinensis for weighing recipe quantity are crushed, and are placed in seepage bucket, are added 60-80%
Effusion is collected in ethanol solution, immersion, is concentrated, and is dried, and fine powder is made；
B. Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood and the radix bupleuri of recipe quantity are weighed, water is added, 1-3h is soaked
Afterwards, decoction three times is added water, decoction liquor is collected, filtering adds absolute ethyl alcohol, stirred, stands, and collects supernatant, concentrates, is made
Mixed powder；
C. the Radix Astragali of recipe quantity is weighed, Ultramicro-powder is made in ultramicro grinding；
D. Ultramicro-powder made from mixed powder made from fine powder made from step a, step b and step c is well mixed, be made
Chinese medicine composition.
Embodiment 3
A kind of Chinese medicine composition for treating chronic pharyngitis, the main bulk drug system by following parts by weight of the Chinese medicine composition
It is standby to form：
Preparation method：Prepared according to the method for embodiment 1.
Embodiment 4
A kind of Chinese medicine composition for treating chronic pharyngitis, the Chinese medicine composition by following parts by weight bulk drug prepare and
Into：
Preparation method：Prepared according to the method for embodiment 1.
Embodiment 5
A kind of Chinese medicine composition for treating chronic pharyngitis, the main bulk drug system by following parts by weight of the Chinese medicine composition
It is standby to form：
Preparation method：Prepared according to the method for embodiment 1.
The aerosol of embodiment 6
Composition 100g prepared by embodiment 1
Additive：Appropriate pH adjusting agent
Preparation method：
A) leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii and the Radix Angelicae Sinensis for weighing recipe quantity are crushed, and are placed in seepage bucket, are added 75% ethanol
After solution 2500ml, immersion 72h, effusion is collected, it is standby；
B) Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood and the radix bupleuri of recipe quantity are weighed, 2000ml water, immersion is added
After 1h, after the boiled 10min of big fire, then 45min is cooked by slow fire；Filtering, collects first time decoction；2000ml is added into the dregs of a decoction
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect second of decoction；2000ml is added into the dregs of a decoction again
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect third time decoction；Merge three decoctions, add
3000ml absolute ethyl alcohols, stirring stands 24h, collects supernatant, reclaims ethanol to decoction 600ml, then add distilled water extremely
2500ml, is made reserve liquid；
C) Radix Astragali of recipe quantity is weighed, Ultramicro-powder is made in ultramicro grinding；
D) reserve liquid made from effusion made from step a) and step b) is merged, mixed liquor is made, add anhydrous second
Alcohol, makes alcohol content in mixed liquor reach 15%-20%, adds pH adjusting agent, and regulation pH value is 5-8；Add step c) obtained
Ultramicro-powder, is well mixed, and is made.
The aerosol of embodiment 7
Composition 100g prepared by embodiment 1
Additive：Triethanolamine stearate 17g
Methylcellulose 3.4g
Preparation method：
A) leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii and the Radix Angelicae Sinensis for weighing recipe quantity are crushed, and are placed in seepage bucket, are added 75% ethanol
After solution 2500ml, immersion 72h, effusion is collected, it is standby；
B) Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood and the radix bupleuri of recipe quantity are weighed, 2000ml water, immersion is added
After 1h, after the boiled 10min of big fire, then 45min is cooked by slow fire；Filtering, collects first time decoction；2000ml is added into the dregs of a decoction
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect second of decoction；2000ml is added into the dregs of a decoction again
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect third time decoction；Merge three decoctions, add
3000ml absolute ethyl alcohols, stirring stands 24h, collects supernatant, reclaims ethanol to decoction 600ml, then add distilled water extremely
2500ml, is made reserve liquid；
C) Radix Astragali of recipe quantity is weighed, Ultramicro-powder is made in ultramicro grinding；
D) reserve liquid made from effusion made from step a) and step b) is merged, mixed liquor is made, add anhydrous second
Alcohol, makes alcohol content in mixed liquor reach 15%-20%；Ultramicro-powder made from step c) is added, is well mixed, Chinese medicine mixing is made
Liquid；
E) it is 1 triethanolamine stearate and methylcellulose to be added into ratio of weight and number:In 1 absolute ethyl alcohol, stirring
Uniformly, Chinese medicine mixed liquor is added, continues to stir 30min, is made.
The aerosol of embodiment 8
Composition 100g prepared by embodiment 1
Additive：Triethanolamine stearate 30g
Methylcellulose 5g
Preparation method：Prepared according to the method for embodiment 7.
The aerosol of embodiment 9
Preparation method：
A) leaf of bamboo, radix glycyrrhizae, akebi, Ligusticum wallichii and the Radix Angelicae Sinensis for weighing recipe quantity are crushed, and are placed in seepage bucket, are added 75% ethanol
After solution 2500ml, immersion 72h, effusion is collected, it is standby；
B) Rabdosia rubescens, the coptis, radix scutellariae, donkey-hide gelatin, the tuber of pinellia, monkshood and the radix bupleuri of recipe quantity are weighed, 2000ml water, immersion is added
After 1h, after the boiled 10min of big fire, then 45min is cooked by slow fire；Filtering, collects first time decoction；2000ml is added into the dregs of a decoction
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect second of decoction；2000ml is added into the dregs of a decoction again
After water, the boiled 10min of big fire, then 45min is cooked by slow fire, filtered, collect third time decoction；Merge three decoctions, add
3000ml absolute ethyl alcohols, stirring stands 24h, collects supernatant, reclaims ethanol to decoction 600ml, then add distilled water extremely
2500ml, is made reserve liquid；
C) Radix Astragali of recipe quantity is weighed, Ultramicro-powder is made in ultramicro grinding；
D) reserve liquid made from effusion made from step a) and step b) is merged, mixed liquor is made, add anhydrous second
Alcohol, makes alcohol content in mixed liquor reach 15%-20%；Ultramicro-powder made from step c) is added, is well mixed, Chinese medicine mixing is made
Liquid；
E) it is 1 triethanolamine stearate and methylcellulose to be added into ratio of weight and number:In 1 absolute ethyl alcohol, stirring
Uniformly, Chinese medicine mixed liquor is added, continues to stir 30min, potassium sorbate and lauryl sodium sulfate is being added, is stirring, making
.
The aerosol of embodiment 10
Preparation method：Prepared according to the method for embodiment 9.
The emulsifying effectiveness of test example 1 is determined
1. in Chinese medicine composition-aqueous systems that emulsifying agent is added to treatment chronic pharyngitis, emulsifying under certain pressure,
Then 3000rmin again-1Lower centrifugation 15min, takes subnatant, under 540nm wavelength, surveys its light transmittance, light transmittance is smaller, effect
Fruit is better.
2. different emulsifiers are to the emulsifying effectiveness of the Chinese medicine composition for the treatment of chronic pharyngitis
Select the triethanolamine stearate and Methyl cellulose of triethanolamine stearate, methylcellulose and different ratio
Element, surveys it to the emulsifying effectiveness for the Chinese medicine composition for treating chronic pharyngitis, the results are shown in Table 1；
Emulsifying effectiveness of the different emulsifiers of table 1 to the Chinese medicine composition for the treatment of chronic pharyngitis
As can be seen from the table, using triethanolamine stearate and methylcellulose blended emulsifier to treatment chronic pharyngitis
The emulsifying effectiveness of Chinese medicine composition be better than single emulsifying agent, and triethanolamine stearate and methylcellulose are by weight
Number is than being 5-7:During 1 mixing, emulsifying effectiveness is best.
The comparitive study of test example 2
1. selected crowd
Patients with chronic pharyngitis 55 is selected, the age is between 25-60 Sui, men and women does not limit.
2. packet and administration
55 patients with chronic pharyngitis are randomly divided into the people for the treatment of group 31, the people of control group 24；Implementation of the present invention is given by treatment group
Aerosol described in example 6, one for several times；Control group gives JINHOUJIAN PENWUJI (main component：Blumea oil, Fructus cinnamomi camphorae
Oil, menthol, ammonium glycyrrhizinate), one is for several times, and two groups are administered 7 days as one therapeutic course.
3. criterion
Recovery from illness：Clinical symptoms all disappear；
It is effective：Clinical symptoms are clearly better；
Effectively：Clinical symptoms have taken a turn for the better；
It is invalid：It is unchanged before and after treatment.
4. result
2 courses for the treatment of are administered in treatment group and control group, and two groups of therapeutic effects to chronic pharyngitis are shown in Table 2；
2 two groups of comparitive studies to chronic pharyngitis of table
5. conclusion
The aerosol that the present invention is provided has good curative effect to chronic pharyngitis, and effective percentage reaches 100%, height evident in efficacy
Recurred in control group, and not.
Model case
Zhang, man, 50 years old, throat was dry and astringent, has foreign body sensation, burning heat sensation, always there is phlegm, is diagnosed as chronic pharyngitis；Use this hair
The aerosol of bright embodiment 6, is all disappeared using 1 course for the treatment of symptom, is continuing with after 1 course for the treatment of, fully recovered, paid a return visit after half a year,
Do not recur.
Sun, female 30 years old, suffers from chronic pharyngitis for many years, and it is dark red that pharyngeal inspection is shown in that mucous membrane diffuses hyperemia, blood vessel dilatation, color, attached
There is a small amount of sticky secretion；The aerosol of the present invention is taken, for several times daily, after two courses for the treatment of, recovery from illness；Follow-up is not recurred after 1 year.
Claims (7)
1. a kind of Chinese medicine composition for treating chronic pharyngitis, it is characterised in that the Chinese medicine composition is by following parts by weight
Bulk drug is prepared from：
2. the Chinese medicine composition of chronic pharyngitis is treated as claimed in claim 1, it is characterised in that the Chinese medicine composition is main
It is prepared from by the bulk drug of following parts by weight：
3. the aerosol being made up of the Chinese medicine composition and additives of the treatment chronic pharyngitis described in claim 1, its feature exists
In the ratio of weight and number of the Chinese medicine composition and additives is 1:0.2-0.5.
4. aerosol as claimed in claim 3, it is characterised in that the additives include pH adjusting agent.
5. aerosol as claimed in claim 3, it is characterised in that the additives also include triethanolamine stearate and first
The mixture of base cellulose, the ratio of weight and number of the triethanolamine stearate and methylcellulose is 5-7:1.
6. aerosol as claimed in claim 5, it is characterised in that the additives also include potassium sorbate and dodecyl sulphur
The ratio of weight and number of the mixture of sour sodium, the potassium sorbate and lauryl sodium sulfate is 2-3:1.
7. the Chinese medicine composition of the treatment chronic pharyngitis as described in claim 1-2 is any is preparing for treating chronic pharyngitis
Application in medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410418303.5A CN104189572B (en) | 2014-08-22 | 2014-08-22 | Treat the Chinese medicine composition and its aerosol and preparation method of chronic pharyngitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410418303.5A CN104189572B (en) | 2014-08-22 | 2014-08-22 | Treat the Chinese medicine composition and its aerosol and preparation method of chronic pharyngitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104189572A CN104189572A (en) | 2014-12-10 |
| CN104189572B true CN104189572B (en) | 2017-09-29 |
Family
ID=52075043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410418303.5A Expired - Fee Related CN104189572B (en) | 2014-08-22 | 2014-08-22 | Treat the Chinese medicine composition and its aerosol and preparation method of chronic pharyngitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104189572B (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100592919C (en) * | 2003-12-31 | 2010-03-03 | 西安亨通光华制药有限公司 | Spray for treating chronic pharyngitis |
| CN101611864A (en) * | 2008-06-26 | 2009-12-30 | 赵朋 | Heat-clearing and fire-purging health tea for old people |
| CN102100757B (en) * | 2010-12-29 | 2012-12-19 | 西藏奇正藏药股份有限公司 | Qingpeng spray preparation for relieving pain and swelling and preparation method thereof |
| CN103432547A (en) * | 2013-08-28 | 2013-12-11 | 李新民 | Formula for treating rhinosalpingitis |
-
2014
- 2014-08-22 CN CN201410418303.5A patent/CN104189572B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN104189572A (en) | 2014-12-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105582333A (en) | Okra wine capable of preserving health and tonifying kidneys and preparation method thereof | |
| CN103749822B (en) | A kind of fruit of glossy privet hypertension and hyperlipemia health protection tea and preparation method thereof | |
| CN104367879A (en) | Pharmaceutical composition for chickens' internal lesion caused by overexertion and preparation method of pharmaceutical composition | |
| CN106420490A (en) | Traditional Chinese medicine composition with effect of removing acne and preparation method and application of traditional Chinese medicine composition | |
| CN103055116B (en) | Traditional Chinese medicine composition for treating acnes | |
| CN104758591A (en) | Traditional Chinese medicinal composition for treating epilepsy, transient tic disorder and hyperactivity | |
| CN102784221A (en) | Traditional Chinese medicine composition for treating constipation and preparation method and clinical preparation thereof | |
| CN103536838A (en) | Traditional Chinese medicine preparation for treating threatened abortion and preparation method thereof | |
| CN103655315B (en) | Black eye removal eye mask and preparation method thereof | |
| CN107375605A (en) | Semifluid extract of deer foetus and preparation method thereof | |
| KR20120009192A (en) | Oriental herbal bathing material and manufacturing method thereof | |
| CN104189572B (en) | Treat the Chinese medicine composition and its aerosol and preparation method of chronic pharyngitis | |
| CN104906430A (en) | Traditional Chinese medicine preparation for treating xerophthalmia and preparation method thereof | |
| CN104873805A (en) | Traditional Chinese medicine preparation for treating cold and preparation method and application | |
| CN104398734B (en) | A kind of Ramulus Taxilli oral solution of blood-enriching face-nourishing and preparation method thereof | |
| CN104524479B (en) | A kind of Chinese medicine composition for treating premenstrual syndrome and preparation method thereof | |
| CN104027433B (en) | A kind of Chinese medicine composition and preparation method thereof and clinical preparation | |
| CN105456947A (en) | Pharmaceutical composition for treating avascular necrosis of femoral head and application thereof | |
| CN104800562A (en) | Traditional Chinese medicine composition for treating oral lichen planus and preparation method thereof | |
| CN105169278A (en) | Dandelion oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof | |
| CN103751418A (en) | Traditional Chinese medicine composition for treating restless leg syndrome | |
| CN103705868B (en) | One treats hyperthyroid pharmaceutical composition and application thereof | |
| CN105920189A (en) | Traditional Chinese medicine composition for treating talalgia due to liver-kidney deficiency and preparation method thereof | |
| CN105998532A (en) | Preparation method for traditional Chinese medicine for treating Qi-stagnancy and blood stasis painful heel and composition of traditional Chinese medicine | |
| CN104800568A (en) | Traditional Chinese medicinal capsules used for alleviating postpartum constipation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170929 Termination date: 20190822 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |