CN104173974A - Medicine for treating psoriasis and preparation method thereof - Google Patents

Abstract

The invention provides a medicine for treating psoriasis and a preparation method thereof. The medicine is prepared from a component A, a component B and a component C, wherein the component A is prepared from cicada slough, ephedra, saposhnicovia divaricata, dried rehamnnia root and phryma leptostachya; the component B is prepared from sichuan lovage rhizome, scutellaria baicalensis, fructus kochiae, serissa serissoide and cortex dictamni; and the component C is prepared from garlic, fragrant-flowered garlic, raw ginger and edible vinegar. The medicine is prepared by reasonable compatibility of traditional Chinese medicinal materials and a specific decoction process, so that effective components in the medicinal materials can be sufficiently extracted, and drug effects can be played. The medicine has the effects of sterilizing and diminishing inflammation, promoting granulation and physically treating, and is capable of effectively killing bacteria causing psoriasis, eliminating dead skin and promoting skin growth, and skin newly growing on an affected position accords with the color of skin on other positions. Experiments prove that the cure rate of psoriasis is 100 percent.

Description

A kind of pharmaceutical treatment of psoriasis and preparation method thereof

Technical field

The present invention relates to the diagnosis of disease and the medicine that use in treatment field, specifically a kind of pharmaceutical treatment of psoriasis and preparation method thereof.

Background technology

Psoriasis is a kind of disease of chronic and refractory skin pruritus, is equivalent to neurodermatitis, and because it is apt to occur in cervical region, shape is as the skin of cattle neck, thick and hard and gain the name.Clinical characters is skin lichenization, plump coarse, acute pruritus, and the course of disease is slow, outbreak repeatedly, constant year does not heal, rear easily recurrence, the multiple positions such as neck, elbow, sacrum of being born in, turn to feature with skin pruritus, lichen.

Summary of the invention

The object of this invention is to provide a kind of antipsoriatics thing, a kind of pharmaceutical treatment of psoriasis and preparation method thereof, is used this product to be applied in affected part, can effectively cure psoriasis, makes the local skin color of illing skin and all the other identical simultaneously.

The present invention solves the problems of the technologies described above the technical scheme of employing to be: a kind of pharmaceutical treatment of psoriasis, by component A, B component and component C, made, according to weight ratio, described component A is made by 6-8 part Periostracum Cicadae, 10-12 part Herba Ephedrae, 13-15 part Radix Saposhnikoviae, 8-9 part Radix Rehmanniae and 5-7 part Herba speranskiae tuberculatae, described B component is made by 13-15 part Rhizoma Chuanxiong, 11-13 part Radix Scutellariae, 10-12 part Fructus Kochiae, 20-22 part Serissa foetida and 10-12 part Cortex Dictamni, and described component C is made by the vinegar of 7-9 part Bulbus Allii, 13-15 part Folium Allii tuberosi, 3-5 part Rhizoma Zingiberis Recens and 50-55 part.

In described component A, also contain 10-12 part fresh Herba Taraxaci and 7-8 part Herba Hedyotidis Diffusae; In B component, also contain 8-9 part Flos Carthami and 10-12 part Fructus Gardeniae, in component C, also contain 9-11 part Semen Armeniacae Amarum.

The preparation method of above-mentioned psoriasis coating cream, comprises the following steps:

1) according to above-mentioned requirement, take respectively each medical material of component A, B component and component C, standby;

2) each medical material of component A is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medicinal liquid A, standby;

3) medical material of each except ethanol in B component is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medical liquid B, standby;

4) by making fineness after the Bulbus Allii in component C, Folium Allii tuberosi, Rhizoma Zingiberis Recens and Semen Armeniacae Amarum oven dry, be no more than 40 object powder, again this powder is put into the container of boiling medicine, and add wherein load weighted vinegar, then decoct, while decocting, first boil with high heat, then use slow fire boiling instead, until the 20-30% of the former liquid level of liquid level simmer down to wherein, then, filtering medicinal residues wherein, obtain medicinal liquid C, standby

5) will after medicinal liquid C, medicinal liquid A and medical liquid B mix homogeneously, make product.

Pharmacology and the property of medicine of the present invention's medical material used are as follows:

Periostracum Cicadae: be the shell after the emergence of cicada Cryptotympana atrata Fabr..Sweet in the mouth, cold in nature, returns lung, Liver Channel, has loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic effect.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, the diseases such as tetanus;

Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature, return lung, urinary bladder channel, there is diaphoresis cold expelling, depressed lung-energy dispersing, the effect of inducing diuresis to remove edema;

Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature.Return bladder, liver, spleen channel.There is expelling pathogenic wind from the body surface, removing dampness to relieve pain, the effect that relieving convulsion is jerked surely.Cure mainly diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, the diseases such as tetanus;

The Radix Rehmanniae: there is heat clearing away, promote the production of body fluid, moisturize, the effect of laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, regulating menstruation, the incised wound stasis of blood, removing heat from blood, hemostasis;

Herba speranskiae tuberculatae: have blood circulation promoting and blood stasis dispelling, diuresis removing toxic substances, the deep effect of stimulating the menstrual flow, fresh grass is mashed external application, can control the swollen pain of furuncle, insect-bite;

Rhizoma Chuanxiong: acrid in the mouth, warm in nature, return liver, gallbladder, pericardium channel, there is the effect of blood-activating and qi-promoting, wind-expelling pain-stopping;

Radix Scutellariae: be labiate Radix Scutellariae, with root, be used as medicine, have heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions, cures mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle;

The Fructus Kochiae: cold in nature, acrid in the mouth, hardship, enter kidney, urinary bladder channel; Function cures mainly: clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching; For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus;

Serissa foetida: have another name called Caulis et folium pavettae hongkongensis, broken leaf Ilicis Purpureae, Radix Serissae, know tender tea leaves; Lightly seasoned, micro-pungent, cool in nature.There is invigorating spleen to remove dampness, the effect that soothing liver-QI is invigorated blood circulation.For infantile malnutrition, acute, chronic hepatitis, amenorrhea, leucorrhea, lumbago due to pathogenic wind-dampness;

Cortex Dictamni: be the root bark of Rutaceae herbaceos perennial shaggy-fruited dittany and Dictamnus angustifolius, bitter in the mouth, salty, cold in nature, return spleen channel, lung meridian, small intestine meridian, stomach warp, urinary bladder channel; The effect with heat clearing and damp drying, dispelling wind for relieving itching, removing toxic substances; Cure mainly: the rubella due to wind heat noxious dampness, eczema, scabies, jaundice, damp-heat arthralgia;

Bulbus Allii: warm in nature, acrid in the mouth is flat; Enter spleen, stomach, lung meridian; Function cures mainly: removing toxic substances parasite killing, reducing swelling and alleviating pain, antidiarrheal dysentery relieving, control lung, anthelmintic; In addition also have warming the spleen warming the stomach, control swollen ulcer drug, white bald tinea skin ulcer, dysentery, have loose bowels, the effect of pulmonary tuberculosis, pertussis, ascarid pinworm, eating accumulation, coldness and pain in the epigastrium, edema distension, circulation of qi promoting removing food stagnancy, parasite killing removing toxic substances;

Folium Allii tuberosi (the present invention adopts full Folium Allii tuberosi, and existing Folium Allii tuberosi leaf also has Radix Folium Allii tuberosi): Radix Folium Allii tuberosi acrid in the mouth, warm in nature; Enter liver, stomach, kidney channel, have the effect of warming middle-JIAO appetizing, promoting flow of QI and blood, reinforcing the kidney and supporting YANG, dissipating blood stasis; Folium Allii tuberosi leaf sweet in the mouth, pungent, salty, warm in nature, enters liver, stomach, kidney channel, has the effect of warming middle-JIAO to promote flow of QI, dissipating blood stasis removing toxic substances;

Rhizoma Zingiberis Recens: warm in nature, acrid in the mouth, returns lung, spleen, stomach warp, has the effect of relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, for Deficiency and coldness of spleen and stomach, loss of appetite, nausea and vomiting, or vomiting due to fluid-retention, the vomiting of disorder of stomach-QI; Wind and cold or cold-phlegm cough; Cold, fever with aversion to wind, nasal obstruction headache;

Fresh Herba Taraxaci: choose fresh and tender Herba Taraxaci Herb (so that making full use of its inner juice), sweet in the mouth, micro-hardship, cold in nature, there is the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Cure mainly: upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swell and ache, gastritis, dysentery, hepatitis, gallbladder are assisted inflammation, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis, controlled acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection;

Herba Hedyotidis Diffusae: have another name called two leaf humulus, bitter in the mouth, micro-sweet, cold nature, GUIXIN, liver, spleen channel; The effect with heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, inducing diuresis to remove edema, for diseases such as laryngopharynx swelling and pain, dyspnea and cough due to lung-heat, the puckery pain of pyretic stranguria, jaundice due to damp-heat, venom, the swollen hot carbuncles of skin ulcer;

Fructus Gardeniae: bitter in the mouth, cold in nature, enter the heart, liver, lung, stomach warp; Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quenches one's thirst, conjunctival congestion, pharyngalgia, spits blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains the disease such as swell and ache;

Vinegar in the present invention is conventional edible vinegar, in shop and supermarket, all can buy.

Beneficial effect: the present invention selects above-mentioned Chinese crude drug to carry out rational compatibility, and by unconventionally making up a prescription, specifically boil technique and make, effective ingredient in medical material can be extracted fully, contribute to the performance of drug effect, the effect with bactericidal antiphlogistic, granulation promoting physical therapy, can effectively kill and cause psoriasic pathogenic bacteria, eliminates dead bark, promote the growth of skin, and the skin that affected part is newly grown is consistent with other position skin colors.Experiment showed, psoriasic cure rate has been reached to 100%.

The specific embodiment

Below in conjunction with specific embodiment, the present invention is further elaborated, and the present invention medical material Jun Keyou pharmacy used obtains or field acquisition obtains.

Embodiment 1

A kind of pharmaceutical treatment of psoriasis, by component A, B component and component C, made, according to weight ratio, described component A is made by 6 portions of Periostracum Cicadaes, 10 portions of Herba Ephedraes, 13 parts of Radix Saposhnikoviaes, 8 parts of Radix Rehmanniae and 5 parts of Herba speranskiae tuberculataes, described B component is made by 13 parts of Rhizoma Chuanxiong, 11 parts of Radix Scutellariaes, 10 parts of Fructus Kochiae, 20 parts of Serissa foetida and 10 parts of Cortex Dictamni, and described component C is made by the vinegar of 7 portions of Bulbus Alliis, 13 portions of Folium Allii tuberosi, 3 portions of Rhizoma Zingiberis Recenss and 50 parts.

In described component A, also contain 10 parts of fresh Herba Taraxaci and 7 parts of Herba Hedyotidis Diffusaes; In B component, also contain 8 parts of Flos Carthamis and 10 parts of Fructus Gardeniae, in component C, also contain 9 parts of Semen Armeniacae Amarums.

The preparation method of above-mentioned psoriasis coating cream, comprises the following steps:

1) according to above-mentioned requirement, take respectively each medical material of component A, B component and component C, standby;

2) each medical material of component A is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medicinal liquid A, standby;

3) medical material of each except ethanol in B component is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medical liquid B, standby;

4) by making fineness after the Bulbus Allii in component C, Folium Allii tuberosi, Rhizoma Zingiberis Recens and Semen Armeniacae Amarum oven dry, be no more than 40 object powder, again this powder is put into the container of boiling medicine, and add wherein load weighted vinegar, then decoct, while decocting, first boil with high heat, then use slow fire boiling instead, until the 20-30% of the former liquid level of liquid level simmer down to wherein, then, filtering medicinal residues wherein, obtain medicinal liquid C, standby

5) will after medicinal liquid C, medicinal liquid A and medical liquid B mix homogeneously, make product.

Embodiment 2

A kind of pharmaceutical treatment of psoriasis, by component A, B component and component C, made, according to weight ratio, described component A is made by 8 portions of Periostracum Cicadaes, 12 portions of Herba Ephedraes, 15 parts of Radix Saposhnikoviaes, 9 parts of Radix Rehmanniae and 7 parts of Herba speranskiae tuberculataes, described B component is made by 15 parts of Rhizoma Chuanxiong, 13 parts of Radix Scutellariaes, 12 parts of Fructus Kochiae, 22 parts of Serissa foetida and 12 parts of Cortex Dictamni, and described component C is made by the vinegar of 9 portions of Bulbus Alliis, 15 portions of Folium Allii tuberosi, 5 portions of Rhizoma Zingiberis Recenss and 55 parts.

In described component A, also contain 12 parts of fresh Herba Taraxaci and 8 parts of Herba Hedyotidis Diffusaes; In B component, also contain 9 parts of Flos Carthamis and 12 parts of Fructus Gardeniae, in component C, also contain 11 parts of Semen Armeniacae Amarums.

The preparation method of above-mentioned psoriasis coating cream, comprises the following steps:

1) according to above-mentioned requirement, take respectively each medical material of component A, B component and component C, standby;

2) each medical material of component A is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medicinal liquid A, standby;

3) medical material of each except ethanol in B component is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medical liquid B, standby;

4) by making fineness after the Bulbus Allii in component C, Folium Allii tuberosi, Rhizoma Zingiberis Recens and Semen Armeniacae Amarum oven dry, be no more than 40 object powder, again this powder is put into the container of boiling medicine, and add wherein load weighted vinegar, then decoct, while decocting, first boil with high heat, then use slow fire boiling instead, until the 20-30% of the former liquid level of liquid level simmer down to wherein, then, filtering medicinal residues wherein, obtain medicinal liquid C, standby

5) will after medicinal liquid C, medicinal liquid A and medical liquid B mix homogeneously, make product.

Embodiment 3

A kind of pharmaceutical treatment of psoriasis, by component A, B component and component C, made, according to weight ratio, described component A is made by 7 portions of Periostracum Cicadaes, 11 portions of Herba Ephedraes, 14 parts of Radix Saposhnikoviaes, 8.5 parts of Radix Rehmanniae and 6 parts of Herba speranskiae tuberculataes, described B component is made by 14 parts of Rhizoma Chuanxiong, 12 parts of Radix Scutellariaes, 11 parts of Fructus Kochiae, 21 parts of Serissa foetida and 11 parts of Cortex Dictamni, and described component C is made by the vinegar of 8 portions of Bulbus Alliis, 14 portions of Folium Allii tuberosi, 4 portions of Rhizoma Zingiberis Recenss and 52 parts.

In described component A, also contain 11 parts of fresh Herba Taraxaci and 7.5 parts of Herba Hedyotidis Diffusaes; In B component, also contain 8.5 parts of Flos Carthamis and 11 parts of Fructus Gardeniae, in component C, also contain 10 parts of Semen Armeniacae Amarums.

The preparation method of above-mentioned psoriasis coating cream, comprises the following steps:

1) according to above-mentioned requirement, take respectively each medical material of component A, B component and component C, standby;

2) each medical material of component A is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medicinal liquid A, standby;

3) medical material of each except ethanol in B component is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medical liquid B, standby;

4) by making fineness after the Bulbus Allii in component C, Folium Allii tuberosi, Rhizoma Zingiberis Recens and Semen Armeniacae Amarum oven dry, be no more than 40 object powder, again this powder is put into the container of boiling medicine, and add wherein load weighted vinegar, then decoct, while decocting, first boil with high heat, then use slow fire boiling instead, until the 20-30% of the former liquid level of liquid level simmer down to wherein, then, filtering medicinal residues wherein, obtain medicinal liquid C, standby

5) will after medicinal liquid C, medicinal liquid A and medical liquid B mix homogeneously, make product.

The using method of this product: this product is applied in to affected part with cotton swab, every day two to three times, 15 days is a course for the treatment of;

Model case

Case 1: Hu, man, 27 years old, from March, 2012, start upper limb and occur red rash, all there is fragmentary erythra in metathorax, the back of the body, extremity etc., at Luoyang City's hospital diagnosis, is psoriasis; In in November, 2012 here medical, there is large stretch of erythra in its back, above covers white scales; Use product of the present invention to take effect after the course for the treatment of, recovery from illness after three months.

Case 2: in certain, female, 32 years old, from 2011, start back and occur red pimple, after scratching, there is white scales.In here, be diagnosed as psoriasis, illing skin flushing, above covers white squama; Use product of the present invention to take effect after 1 course for the treatment of, recovery from illness after 2 months;

Case 3: Zhang, female, 41 years old, from June, 2010, start upper limb elbow joint and occur red beans size pimple, above cover white scales.Aggravation in 2011, is diagnosed as psoriasis after to our hospital, and large stretch of pimple appears in its upper limb joint portion, and squama is thicker, wipes visible thin film and hemorrhage after squama off; Use this product to take effect after 1 month, recovery from illness after 4 months;

Case 4: Chen, man, 32 years old, from 2012 the end of the year head start to occur red pimple, after scratching, see white scales; Rear aggravation in April, 2013 here be diagnosed as psoriasis, its back also occurs that large stretch of pimple, squama are thicker, wipes visible thin film and petechia after squama off; Use this product to take effect after 1 month, recovery from illness after 3 months.

Claims (3)

1. a pharmaceutical treatment of psoriasis, it is characterized in that: by component A, B component and component C, made, according to weight ratio, described component A is made by 6-8 part Periostracum Cicadae, 10-12 part Herba Ephedrae, 13-15 part Radix Saposhnikoviae, 8-9 part Radix Rehmanniae and 5-7 part Herba speranskiae tuberculatae, described B component is made by 13-15 part Rhizoma Chuanxiong, 11-13 part Radix Scutellariae, 10-12 part Fructus Kochiae, 20-22 part Serissa foetida and 10-12 part Cortex Dictamni, and described component C is made by the vinegar of 7-9 part Bulbus Allii, 13-15 part Folium Allii tuberosi, 3-5 part Rhizoma Zingiberis Recens and 50-55 part.

2. a kind of pharmaceutical treatment of psoriasis according to claim 1, is characterized in that: in described component A, also contain 10-12 part fresh Herba Taraxaci and 7-8 part Herba Hedyotidis Diffusae; In B component, also contain 8-9 part Flos Carthami and 10-12 part Fructus Gardeniae, in component C, also contain 9-11 part Semen Armeniacae Amarum.

3. the preparation method of pharmaceutical treatment of psoriasis according to claim 2, is characterized in that, comprises the following steps:

1) according to the requirement of claim 2, take respectively each medical material of component A, B component and component C, standby;

2) each medical material of component A is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medicinal liquid A, standby;

3) medical material of each except ethanol in B component is put into the container of boiling medicine, and add wherein the water of 10 times of medical material weight, then decoct, while decocting, first boil with high heat, use again slow fire boiling instead, until water level is wherein reduced to the 10-15% of former water level, then, pull medicinal residues wherein out, obtain medical liquid B, standby;

4) by making fineness after the Bulbus Allii in component C, Folium Allii tuberosi, Rhizoma Zingiberis Recens and Semen Armeniacae Amarum oven dry, be no more than 40 object powder, again this powder is put into the container of boiling medicine, and add wherein load weighted vinegar, then decoct, while decocting, first boil with high heat, then use slow fire boiling instead, until the 20-30% of the former liquid level of liquid level simmer down to wherein, then, filtering medicinal residues wherein, obtain medicinal liquid C, standby

5) will after medicinal liquid C, medicinal liquid A and medical liquid B mix homogeneously, make product.