CN104147539A - Traditional Chinese medicine used for treating gastric ulcer - Google Patents
Traditional Chinese medicine used for treating gastric ulcer Download PDFInfo
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- CN104147539A CN104147539A CN201410430281.4A CN201410430281A CN104147539A CN 104147539 A CN104147539 A CN 104147539A CN 201410430281 A CN201410430281 A CN 201410430281A CN 104147539 A CN104147539 A CN 104147539A
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Abstract
The invention relates to a traditional Chinese medicine used for treating gastric ulcer. The traditional Chinese medicine is prepared from following raw material medicines comprising, by weight, 8 parts of fructus aurantii, 5 parts of bletilla striata, 20 parts of hedyotis diffusa, 10 parts of zedoary, 5 parts of fructus amomi rotundus flowers and 10 parts of dendrobe. A clinical experiment proves that the traditional Chinese medicine can treat gastric ulcer safely and effectively.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine that is used for the treatment of gastric ulcer.
Background technology
Peptic ulcer is a kind of common digestive tract disease, can betide esophagus, stomach or duodenum, also can betide near stomach-intestinal anastomosis mouth or in the Meckel diverticulum that contains gastric mucosa, because gastric ulcer and duodenal ulcer are the most common, therefore general so-called peptic ulcer refers to gastric ulcer and duodenal ulcer.Why it is referred to as peptic ulcer, be because previously think gastric ulcer and duodenal ulcer be due to gastric acid and pepsin formed to mucosa autodigestion, in fact gastric acid and pepsin are the one of the main reasons of ulcer, also have other reasons can form peptic ulcer.Gastric ulcer clinical manifestation is that epigastrium pain is the cardinal symptom of primary disease.Multidigit, in epigastrium, also can appear at after left upper abdomen or breastbone, xiphoid-process.Often be dull pain, dull pain, distending pain, burn sample pain.The many appearance in 1 hour after the meal of pain of gastric ulcer were alleviated gradually, until reappear the above-mentioned rhythm and pace of moving things after the feed of lower meal after 1～2 hour again.Some patients were can be asymptomatic, or using the complication such as hemorrhage, perforation as onset symptoms.
Any age of primary disease all can fall ill, and has hereditary medical history more.Primary disease complication is comparatively serious, brings very large impact to patient's life.
Mechanism of Gastric Ulcer mostly is helicobacter pylori infections, also relevant to the very strong medicine of stomach irritation or tobacco and wine etc. with long-term taking.Western medicine has the medicine that reduces damage factor at present: the synthetics of antacid, anticholinergic agents, H2 receptor antagonist, proglumide, PGE2 and omeprazole etc.; The medicine of gastric mucosal protection: as sucralfate, bismuth, carbenoxolone (carbenoxolone) etc.But its therapeutic effect is all undesirable and side effect is larger.
Primary disease belongs to the traditional Chinese medical science " gastric abscess ", " acid regurgitation ", " cardiac and abdominal pain " category according to its clinical manifestation.
Medical material present Research involved in the present invention is as follows:
Fructus Aurantii [source] this product is rutaceae Citrus aurantium Linn. (CiTCMLIBus aurantium L.) and cultivation product green fruit thereof.Late July, to early August, plucks during the nearly maturation of fruit, trains greatly product green fruit.[nature and flavor] are bitter, sour, are slightly cold.[return through] returns lung, spleen, liver, stomach, large intestine channel.[function cures mainly] septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen; Heavy after dysentery, proctoptosis; Uterine prolapse.[usage and dosage] 3 ~ 9g.The careful clothes of [attention] weakness of the spleen and stomach and anemia of pregnant woman.
Pseudobulbus Bletillae (Rhizoma Bletillae) [source] this product is the rhizome of orchid Pseudobulbus Bletillae (Rhizoma Bletillae).Excavating the 9-10 month after plantation 3-4, by in rhizome immersion about approximately 1 hour, clean earth, except a fibrous root, through steaming and decocting, to inner face, take out during without the white heart, shine or a heatable brick bed stiff when non-caked to surface, with sulfur after smoked 1 night, dry or a heatable brick bed dry, then hit residual palpus, make surface become bright and clean yellowish white, sieve decontamination.[nature and flavor] are bitter, sweet, puckery, cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] astringing to arrest bleeding, detumescence and promoting granulation.Main spitting of blood, spits blood, and epistaxis, has blood in stool, traumatic hemorrhage; Carbuncle pyogenic infections from tumour or sore; Scald and burn, rhagadia manus et pedis, anal fissure.[usage and dosage] 3 ~ 10g.
Herba Hedyotidis Diffusae [source] this product is the whole herb with root of dicotyledon medicine Maguireothamnus speciosus Herba Hedyotidis Diffusae.Summer, autumn gather, and dry or using fresh herb.[nature and flavor] are bitter, sweet, cold.[return through] GUIXIN, liver, spleen, large intestine channel.[function cures mainly] heat-clearing and toxic substances removing, dampness removing.Main dyspnea and cough due to lung-heat, laryngopharynx swelling and pain; Acute appendicitis, furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria, edema; Dysentery, intestinal is scorching; Jaundice due to damp-heat; Cancerous protuberance.[usage and dosage] 15 ~ 30g.
Rhizoma Curcumae [source] this product is the rhizome of zingiberaceous plant Rhizoma Curcumae, Guangxi zedoary and RADIX CURCUMAE.In 12 months, the last ten-days period, when aerial parts is withered, excavate root, remove the earth on rhizome, clean, put and in pot, steam or boil approximately 15 minutes, dry or dry, hit fibrous root.[nature and flavor] are pungent, bitter, temperature.[return through] returns liver, spleen channel.[function cures mainly] circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.Main vim and vigour are pained, eating accumulation, abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhea, lump in the abdomen tumor mass in the abdomen, traumatic injury.[usage and dosage] 3 ~ 10g.
Flos Amomi Rotundus [source] this product is zingiberaceous plant Fructus Amomi Rotundus Amomum kravanh Pierre ex Gagnep.Or the dried floral of amomum compactum Soland ex Maton Amomum compactum Soland ex Maton.[nature and flavor] are pungent, temperature.[return through] returns lung, spleen, stomach warp.[function cures mainly] removing dampness circulation of qi promoting, warming middle-JIAO to arrest vomiting.Be applicable to the diseases such as the cold-damp stagnation of QI, gastral cavity abdominal distention are vexed, anorexia, vomiting.[usage and dosage] 3～6g.
Herba Dendrobii [source] this product is the stem of orchid Dendrobium nobile, U.S. flower Herba Dendrobii, Herba Dendrobii, Dendrobium chrysanthum, Herba Dendrobii oculati.Go root to clean, rub the membranaceous sheath of thin with the hands, dry or dry.[nature and flavor] are sweet, are slightly cold.[return through] returns stomach, lung, kidney channel.[function cures mainly] stomach reinforcing that promotes the production of body fluid, nourishing YIN and clearing away heat, lung moistening kidney tonifying, the strong waist of improving eyesight.Main consumption of body fluid caused by febrile disease, xerostomia excessive thirst; Deficiency of stomach-Yin, stomachache is retched; Dryness of the lung dry cough, deficiency-heat is not moved back; It is dark that the moon is hindered order; Waist knee joint is weak.[usage and dosage] 6 ~ 15g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of gastric ulcer, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing gastric ulcer.
In order to achieve the above object, the present invention is by the following technical solutions:
A Chinese medicine that is used for the treatment of gastric ulcer, is characterized in that, it is that raw medicinal material by following weight proportion is prepared from: 8 parts of Fructus Aurantiis, 5 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 parts of Herba Hedyotidis Diffusaes, 10 parts of Rhizoma Curcumae, 5 parts of Flos Amomi Rotundus, 10 parts of Herba Dendrobiis.
Inventor think gastric ulcer etiology and pathogenesis mainly due to feelings will hinder, improper diet and overtiredness etc.Be worried angry, seven emotions stimulate, the liver failing to maintain the normal flow of QI, horizontal criminal's stomach internal organs; Or stagnation of spleen-QI, dysfunction of the spleen in transportation and transformation; Intemperance of taking food or partially have a liking for impairing the spleen and stomach; Or burnt in damp and hot heap soil or fertilizer over and around the roots knot, stomach film is impaired, all can cause ulcer and occur.Long-term muscle power or mental work are excessive, impairment of the spleen consumption gas, and transporting is sluggish, and QI and blood is lost smooth, and stomach film is not raw, and easily sends out primary disease.The sick position of primary disease is at stomach, the closest with liver spleen relation, aspect change of pathogenesis, has by gas and blood, and Sthenia is transforming into asthenia, transformation between cold and heat, or injury of YANG due to overabundant cold, the features such as heat-transformation impairment of YIN.Clinical treatment should be take dispersing the stagnated liver-QI for regulating the stomach, warming middle-JIAO and strengthening the spleen, yin nourishing stomach reinforcing, blood circulation promoting and blood stasis dispelling, regulating cold and heat as basic, therefore assembly is our.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor collects outpatient service and patients w ith peptic ulcer disease 56 examples of being in hospital in February, 2012 ~ 2013 altogether between year June, be divided at random treatment group 30 examples and matched group 26 examples, treatment group man 16 examples, female's 14 examples, 18～58 years old age, 38.6 years old mean age, the course of disease 1～4 year; Matched group man 14 examples, female's 12 examples, 20～58 years old age, 38.5 years old mean age, the course of disease 1～4 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
1) the chronic course of disease, periodical attack, often relevant with seasonal variations, Nervous and Mental Factors, improper diet; Or the medicine that long-term taking can cause ulcer is as aspirin etc.; 2) upper abdomen dull pain, causalgia or dull pain, alleviate after taking alkalescent medicine, and typical gastric ulcer is often taken back under xiphoid-process, is apt to occur in half an hour to 1～2 hour after the meal, the normal companion of pain acid regurgitation belch; 3) basis is secreted acid amount and maximum and is secreted acidimetric estimation and help diagnosis, and it is normal or slightly low that acid amount is secreted on the basis of gastric ulcer, but not should be free acid, lacks; 4) ulcer active stage stool blood is positive; 5) the visible niche of x-ray barium meal examination and duplicature such as concentrate at the direct sign, simple local tenderness, and the indirect signs such as excitation distortion are only for referencial use; 6) gastroscopy, can in stomach see circle or oval, bottom is smooth, the ulcer of neat in edge.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group makes according to specific embodiment 1, every day 3 times.8 weeks courses for the treatment of.
The oral cimetidine of matched group, takes according to its description.8 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: treat clinical symptom disappearance after 2 weeks, after 4～7 weeks, gastric ulcer white cicatricial phase is shown in gastroscopy;
Effective: treat clinical symptoms after 2 weeks and obviously alleviate, after 4～7 weeks, gastric ulcer healing phase or red cicatricial phase are shown in gastroscopy;
Invalid: clinical symptoms improvement is undesirable afterwards to treat 7 weeks, and gastroscopy ulcer does not heal.
3.2 therapeutic outcomes are in Table 1.
Table 1 liang group curative effect comparison
| Group | n | Cure | Effective | Invalid | Total effective rate (%) | Serious adverse reaction example |
| Treatment group | 30 | 19 | 9 | 2 | 93.3% | 0 |
| Matched group | 26 | 11 | 9 | 6 | 76.9% | 0 |
Visible, the medicine that the present invention makes can safe and effective treatment gastric ulcer, has promotional value.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Specific embodiment 1
Take: 8 grams of Fructus Aurantiis, 5 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 grams of Herba Hedyotidis Diffusaes, 10 grams of Rhizoma Curcumae, 5 grams of Flos Amomi Rotundus, 10 grams of Herba Dendrobiis; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of normal adult.
Be used for the treatment of gastric ulcer.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: 8 grams of Fructus Aurantiis, 5 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 grams of Herba Hedyotidis Diffusaes, 10 grams of Rhizoma Curcumae, 5 grams of Flos Amomi Rotundus, 10 grams of Herba Dendrobiis; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.
Be used for the treatment of gastric ulcer.Oral, take once every day.
Specific embodiment 3
Take: 8 grams of Fructus Aurantiis, 5 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 grams of Herba Hedyotidis Diffusaes, 10 grams of Rhizoma Curcumae, 5 grams of Flos Amomi Rotundus, 10 grams of Herba Dendrobiis; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, must meet the capsule of one day consumption of normal adult.
Be used for the treatment of gastric ulcer.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. a Chinese medicine that is used for the treatment of gastric ulcer, is characterized in that, it is that raw medicinal material by following weight proportion is prepared from: 8 parts of Fructus Aurantiis, 5 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 parts of Herba Hedyotidis Diffusaes, 10 parts of Rhizoma Curcumae, 5 parts of Flos Amomi Rotundus, 10 parts of Herba Dendrobiis.
2. the Chinese medicine that is used for the treatment of gastric ulcer as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Fructus Aurantiis, 5 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 parts of Herba Hedyotidis Diffusaes, 10 parts of Rhizoma Curcumae, 5 parts of Flos Amomi Rotundus, 10 parts of Herba Dendrobiis; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. the Chinese medicine that is used for the treatment of gastric ulcer as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Fructus Aurantiis, 5 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 parts of Herba Hedyotidis Diffusaes, 10 parts of Rhizoma Curcumae, 5 parts of Flos Amomi Rotundus, 10 parts of Herba Dendrobiis; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packing, obtains powder; Above-mentioned part all refers to weight portion.
4. the Chinese medicine that is used for the treatment of gastric ulcer as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Fructus Aurantiis, 5 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 parts of Herba Hedyotidis Diffusaes, 10 parts of Rhizoma Curcumae, 5 parts of Flos Amomi Rotundus, 10 parts of Herba Dendrobiis; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, obtain capsule; Above-mentioned part all refers to weight portion.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267520A (en) * | 2015-11-18 | 2016-01-27 | 包莉丽 | Medicine for treating chronic gastric ulcer |
| CN105560714A (en) * | 2015-12-25 | 2016-05-11 | 刘震 | Traditional Chinese medicine for treating gastric ulcer and preparation method thereof |
| CN111920908A (en) * | 2020-08-21 | 2020-11-13 | 云南中医药大学 | Pharmaceutical composition for treating peptic ulcer |
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| CN1281713A (en) * | 2000-01-27 | 2001-01-31 | 王念夫 | Weitong capsule for curing stomach-ache |
| KR20080051893A (en) * | 2006-12-07 | 2008-06-11 | 한국 한의학 연구원 | Pharmaceutical composition for treating and preventing gastrointestinal diseases comprising herb extracts |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267520A (en) * | 2015-11-18 | 2016-01-27 | 包莉丽 | Medicine for treating chronic gastric ulcer |
| CN105560714A (en) * | 2015-12-25 | 2016-05-11 | 刘震 | Traditional Chinese medicine for treating gastric ulcer and preparation method thereof |
| CN111920908A (en) * | 2020-08-21 | 2020-11-13 | 云南中医药大学 | Pharmaceutical composition for treating peptic ulcer |
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Application publication date: 20141119 |