CN104147393A - Traditional Chinese composition capable of recuing blood pressure and blood lipid and preparation method thereof - Google Patents
Traditional Chinese composition capable of recuing blood pressure and blood lipid and preparation method thereof Download PDFInfo
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- CN104147393A CN104147393A CN201410426759.6A CN201410426759A CN104147393A CN 104147393 A CN104147393 A CN 104147393A CN 201410426759 A CN201410426759 A CN 201410426759A CN 104147393 A CN104147393 A CN 104147393A
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Abstract
The invention belongs to the field of Chinese herbal medicines and particularly relates to a traditional Chinese composition capable of recuing blood pressure and blood lipid and a preparation method thereof. In the invention, fresh artemisia apiacea and radix rehmanniae are placed into a reaction kettle for reaction and are subjected to a concentrating process with peony roots in a rotary evaporator so that a sufficient action among the fresh artemisia apiacea, the radix rehmanniae and the peony roots is achieved. Finally a mixing process is carried out with other components. A blood pressure reducing function is greatly improved. In addition, the traditional Chinese medicine composition is quick in curative effects and enables a patient to feel a significant improvement just after 3-4 days. All of the components in the traditional Chinese medicine composition are Chinese herbal medicines so that the traditional Chinese medicine composition is free of toxic and side effects and can be widely applied in people in different stages. Raw materials of the traditional Chinese medicine composition are easy to obtain. The traditional Chinese medicine composition is easy to prepare, is low in production cost, is wide in effects, is high in safety and is significant in benefit.
Description
Technical field
The invention belongs to field of Chinese herbal, be specifically related to Chinese medicine composition of a kind of blood pressure lowering, blood fat reducing and preparation method thereof.
Background technology
Hypertension is the disease that continues hyperpiesia, can cause the diseases such as apoplexy, heart disease, hemangioma, renal failure, hypertension is a kind of taking arterial pressure rising as feature, can be functional with heart, blood vessel, brain and kidney and other organs or the systemic disease of organic change, it have essential hypertension and secondary hypertension point.The reason of hypertension incidence is a lot, can be divided into two aspects of h and E.In state-owned 11% people suffer from hypertension, the whole world has 10% people to suffer from hypertension, and patient presses the speed increase of 1.5-2% every year.Suffer from the generation that hypertension often can cause Other diseases, countries in the world medical worker is all at the hypertensive active drug of development treatment.
Although the antihypertensive drug kind of current clinical use is more, many medicines have side effect, and action effect is not obvious, can not play good therapeutical effect.
Summary of the invention
The object of this invention is to provide Chinese medicine composition of a kind of blood pressure lowering, blood fat reducing and preparation method thereof, can play good blood pressure lowering, effect for reducing blood fat, and have no side effect.
The present invention for solving the problems of the technologies described above adopted technical scheme is: the Chinese medicine composition of a kind of blood pressure lowering, blood fat reducing, described Chinese medicine composition is made up of root of Paeonia suffruticosa Ardr., Radix Salviae Miltiorrhizae, fresh Herba Artemisiae Annuae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, the Radix Rehmanniae, Semen Cassiae and Cortex Lycii, and the parts by weight of preparing the required each component of Chinese medicine composition are respectively root of Paeonia suffruticosa Ardr. 5-7 part, Radix Salviae Miltiorrhizae 10-15 part, fresh Herba Artemisiae Annuae 5-6 part, Spica Prunellae 6-10 part, Folium Ginkgo 10-20 part, Rhizoma Gastrodiae 8-15 part, Radix Rehmanniae 5-10 part, Semen Cassiae 10-12 part, Cortex Lycii 10-15 part.
The preparation method of described blood pressure lowering, Chinese medicinal composition for reducing blood fat, comprises the following steps:
Step 1, take each component by the parts by weight of described each component, each component is put into respectively to mortar and grind, and be crushed to 30 orders, for subsequent use;
It is the reactor that 20-25 DEG C, pressure are 0.2-0.3MPa that step 2, fresh Herba Artemisiae Annuae prepared by step 1 and the Radix Rehmanniae are put into temperature, and insulation 2-3h, makes mixture I, for subsequent use;
Step 3, mixture I and root of Paeonia suffruticosa Ardr. are put into temperature is that the Rotary Evaporators of 55 DEG C is concentrated, until solid content reaches 14 ° of Brix, makes mixture II, for subsequent use;
Step 4, Radix Salviae Miltiorrhizae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, Cortex Lycii, Semen Cassiae and mixture II are put into temperature is that the baking oven of 65 DEG C is dried, then pulverize and cross 40 mesh sieves, it is that 0.095MPa, temperature are the dry 1h of vacuum desiccator of 65 DEG C that each component after pulverizing is placed in respectively to vacuum, afterwards dried each component being put into respectively to high-frequency vibration mill pulverizes, make its particle diameter reach 22 μ m, for subsequent use;
Step 5, the each component after pulverizing is mixed and stirred and makes the Chinese medicine composition of blood pressure lowering.
The property of medicine of the present invention's Chinese medicine used is as follows:
Root of Paeonia suffruticosa Ardr.: reduce blood pressure, ease pain, calm, antiinflammatory and refrigeration function; Various pathogens is had to stronger inhibitory action.
Radix Salviae Miltiorrhizae: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.
Fresh Herba Artemisiae Annuae: bitter in the mouth is micro-pungent, cold, heat clearing away, expelling summer-heat, except steaming, control epidemic febrile disease, summer-heat, hectic fever due to YIN-deficiency consumptive fever, malaria, dysentery, jaundice, scabies, pruritus.
Spica Prunellae: cold in nature, sweet in the mouth, pungent, micro-hardship, there is the effect of letting out clearly liver-fire, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, cooling blood for hemostasis, be applicable to lymphoid tuberculosis, goiter, acute mastitis, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, metrorrhagia, leukorrhagia, Fiedeler's disease type hepatitis and bacillary dysentery etc.
Folium Ginkgo: astringe the lung, relieving asthma, blood circulation promoting and blood stasis dispelling, pain relieving.For cough and asthma due to lung deficiency, coronary heart disease, angina pectoris, hyperlipidemia, anticoagulant is solid.
Rhizoma Gastrodiae: calmness, analgesia, anticonvulsant action; Can increase cerebral blood flow, reduce cerebral vascular resistance, slightly shrink cerebrovascular, increase coronary vasodilator flow; Can reduce blood pressure, decreased heart rate, has protective effect to myocardial ischemia; Gastrodia elata polysaccharide has immunocompetence.
The Radix Rehmanniae: bitter but sweet flavor, gas is cold, hemostasis, the kind incised wound for the treatment of, antiabortive gas, stimulates the menstrual flow, and leak-stopping collapses, and all has siddhi.
Cortex Lycii: removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.
Semen Cassiae: bitter in the mouth, sweet, salty, cold nature, enters liver, kidney, large intestine channel; Loosening bowel to relieve constipation, blood fat reducing improving eyesight, treatment constipation and hyperlipidemia, hypertension.Liver heat removing and eyesight improving, diuretic relieving constipation, has laxative action, reducing blood pressure and blood fat.
beneficial effect
One, the present invention is by fresh Herba Artemisiae Annuae and the Radix Rehmanniae are put into reaction kettle for reaction, then it is concentrated to put into Rotary Evaporators together with root of Paeonia suffruticosa Ardr., and fresh Herba Artemisiae Annuae, the Radix Rehmanniae and root of Paeonia suffruticosa Ardr. are fully acted on, and finally mixes with other composition again, has greatly improved effect of blood pressure lowering.And curative effect of the present invention is fast, within 3-4 days, take an evident turn for the better.
Two, component of the present invention is Chinese herbal medicine, has no side effect, and can be widely used in the crowd of different phase.
Three, the raw material in the present invention is easy to get, and preparation is simple, and production cost is lower, and effect extensively, safe, remarkable benefit.
Detailed description of the invention
The Chinese medicine composition of a kind of blood pressure lowering, blood fat reducing, described Chinese medicine composition is made up of root of Paeonia suffruticosa Ardr., Radix Salviae Miltiorrhizae, fresh Herba Artemisiae Annuae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, the Radix Rehmanniae, Semen Cassiae and Cortex Lycii, and the parts by weight of preparing the required each component of Chinese medicine composition are respectively root of Paeonia suffruticosa Ardr. 5-7 part, Radix Salviae Miltiorrhizae 10-15 part, fresh Herba Artemisiae Annuae 5-6 part, Spica Prunellae 6-10 part, Folium Ginkgo 10-20 part, Rhizoma Gastrodiae 8-15 part, Radix Rehmanniae 5-10 part, Semen Cassiae 10-12 part, Cortex Lycii 10-15 part.
The preparation method of described blood pressure lowering, Chinese medicinal composition for reducing blood fat, comprises the following steps:
Step 1, take each component by the parts by weight of described each component, each component is put into respectively to mortar and grind, and be crushed to 30 orders, for subsequent use;
It is the reactor that 20-25 DEG C, pressure are 0.2-0.3MPa that step 2, fresh Herba Artemisiae Annuae prepared by step 1 and the Radix Rehmanniae are put into temperature, and insulation 2-3h, makes mixture I, for subsequent use;
Step 3, mixture I and root of Paeonia suffruticosa Ardr. are put into temperature is that the Rotary Evaporators of 55 DEG C is concentrated, until solid content reaches 14 ° of Brix, makes mixture II, for subsequent use;
Step 4, Radix Salviae Miltiorrhizae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, Cortex Lycii, Semen Cassiae and mixture II are put into temperature is that the baking oven of 65 DEG C is dried, then pulverize and cross 40 mesh sieves, it is that 0.095MPa, temperature are the dry 1h of vacuum desiccator of 65 DEG C that each component after pulverizing is placed in respectively to vacuum, afterwards dried each component being put into respectively to high-frequency vibration mill pulverizes, make its particle diameter reach 22 μ m, for subsequent use;
Step 5, the each component after pulverizing is mixed and stirred and makes the Chinese medicine composition of blood pressure lowering.
Embodiment 1:
The Chinese medicine composition of a kind of blood pressure lowering, blood fat reducing, described Chinese medicine composition is made up of root of Paeonia suffruticosa Ardr., Radix Salviae Miltiorrhizae, fresh Herba Artemisiae Annuae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, the Radix Rehmanniae, Semen Cassiae and Cortex Lycii, and the parts by weight of preparing the required each component of Chinese medicine composition are respectively 5 parts of root of Paeonia suffruticosa Ardr., 10 parts of Radix Salviae Miltiorrhizaes, 5 parts of fresh Herba Artemisiae Annuaes, 6 parts of Spica Prunellaes, 10 parts of Folium Ginkgos, 8 parts, Rhizoma Gastrodiae, 5 parts, the Radix Rehmanniae, 10 parts of Semen Cassiaes, 10 parts of Cortex Lycii.
The preparation method of described blood pressure lowering, Chinese medicinal composition for reducing blood fat, comprises the following steps:
Step 1, take each component by the parts by weight of described each component, each component is put into respectively to mortar and grind, and be crushed to 30 orders, for subsequent use;
It is the reactor that 20 DEG C, pressure are 0.2MPa that step 2, fresh Herba Artemisiae Annuae prepared by step 1 and the Radix Rehmanniae are put into temperature, and insulation 2h, makes mixture I, for subsequent use;
Step 3, mixture I and root of Paeonia suffruticosa Ardr. are put into temperature is that the Rotary Evaporators of 55 DEG C is concentrated, until solid content reaches 14 ° of Brix, makes mixture II, for subsequent use;
Step 4, Radix Salviae Miltiorrhizae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, Cortex Lycii, Semen Cassiae and mixture II are put into temperature is that the baking oven of 65 DEG C is dried, then pulverize and cross 40 mesh sieves, it is that 0.095MPa, temperature are the dry 1h of vacuum desiccator of 65 DEG C that each component after pulverizing is placed in respectively to vacuum, afterwards dried each component being put into respectively to high-frequency vibration mill pulverizes, make its particle diameter reach 22 μ m, for subsequent use;
Step 5, the each component after pulverizing is mixed and stirred and makes the Chinese medicine composition of blood pressure lowering.
Embodiment 2:
The Chinese medicine composition of a kind of blood pressure lowering, blood fat reducing, described Chinese medicine composition is made up of root of Paeonia suffruticosa Ardr., Radix Salviae Miltiorrhizae, fresh Herba Artemisiae Annuae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, the Radix Rehmanniae, Semen Cassiae and Cortex Lycii, and the parts by weight of preparing the required each component of Chinese medicine composition are respectively 7 parts of root of Paeonia suffruticosa Ardr., 15 parts of Radix Salviae Miltiorrhizaes, 6 parts of fresh Herba Artemisiae Annuaes, 10 parts of Spica Prunellaes, 20 parts of Folium Ginkgos, 15 parts, Rhizoma Gastrodiae, 10 parts, the Radix Rehmanniae, 12 parts of Semen Cassiaes, 15 parts of Cortex Lycii.
The preparation method of described blood pressure lowering, Chinese medicinal composition for reducing blood fat, comprises the following steps:
Step 1, take each component by the parts by weight of described each component, each component is put into respectively to mortar and grind, and be crushed to 30 orders, for subsequent use;
It is the reactor that 25 DEG C, pressure are 0.3MPa that step 2, fresh Herba Artemisiae Annuae prepared by step 1 and the Radix Rehmanniae are put into temperature, and insulation 3h, makes mixture I, for subsequent use;
Step 3, mixture I and root of Paeonia suffruticosa Ardr. are put into temperature is that the Rotary Evaporators of 55 DEG C is concentrated, until solid content reaches 14 ° of Brix, makes mixture II, for subsequent use;
Step 4, Radix Salviae Miltiorrhizae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, Cortex Lycii, Semen Cassiae and mixture II are put into temperature is that the baking oven of 65 DEG C is dried, then pulverize and cross 40 mesh sieves, it is that 0.095MPa, temperature are the dry 1h of vacuum desiccator of 65 DEG C that each component after pulverizing is placed in respectively to vacuum, afterwards dried each component being put into respectively to high-frequency vibration mill pulverizes, make its particle diameter reach 22 μ m, for subsequent use;
Step 5, the each component after pulverizing is mixed and stirred and makes the Chinese medicine composition of blood pressure lowering.
Test 1
Collecting 200 has hypertensive patient, is divided into tetra-groups of A, B, C, D.And A group is used Chinese medicine composition of the present invention, B group is used the component of removing after fresh Herba Artemisiae Annuae, the Radix Rehmanniae and root of Paeonia suffruticosa Ardr., and fresh Herba Artemisiae Annuae, the Radix Rehmanniae and the root of Paeonia suffruticosa Ardr. of C group do not react in reactor and Rotary Evaporators, and D group is not used the present invention.
Tri-groups of result of the test: A, B, C hypertension compared with D group takes an evident turn for the better, and after 3-4 days, hypertension start to decline, and the action effect of two groups of B, C is not as A group, and B group is better than C group.
Result shows: the present invention is successful not only, and instant effect.In component of the present invention, fresh Herba Artemisiae Annuae, the Radix Rehmanniae and root of Paeonia suffruticosa Ardr. react in reactor and Rotary Evaporators, have played Main Function.
Clinical data
1,, as the Chinese medicine composition of blood pressure lowering, blood fat reducing, select the routine clinical observation of hyperpietic 200 of making a definite diagnosis, patient to be divided at random two groups for the treatment of group and matched groups, treatment group 100 examples, 35～55 years old age, 40.8 years old mean age, the shortest person of course of disease June, elder 10 years.Matched group 100 examples, 35～55 years old age, 40.1 years old mean age, the shortest person of the course of disease 7 months, elder 12 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection
Treatment group is taken Chinese medicine composition of the present invention, oral, every day 2 times, each 2, warm boiled water;
Matched group is taken commercially available hypotensor composition granule, oral, every day 3 times, each 2, warm boiled water.
3, select in the treatment group of Chinese medicine preparation of the present invention, cure 60 examples, effective 38 examples, invalid 2 examples, cure rate 60%, total effective rate 98%.
In matched group, cure 36 examples, effective 35 examples, invalid 29 examples, cure 36%, total effective rate 71%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
, side certain, man, 48 years old, headache uncomfortable in chest the increasing the weight of of have palpitation, the cool fiber crops of extremity are listless and aching, can not descend to walk, and then go to see a doctor, continuous detecting three times all, about 205/115mmHg, is diagnosed as hypertension.Eat Chinese medicine composition of the present invention every day, and after 30 days, after testing, blood pressure is reduced to 155/85mmHg, arteriosclerosis alleviates, and extremity are felt gradually, continues to take, and after half a year, blood pressure recovers normal, atheromatous plaque reduces simultaneously, and arteriosclerosis takes a turn for the better, and the walking of can leaving the bed, had no bounce-back within 2 years.
, more certain, man, 44 years old.Suffer from hypertension 3 years, often feel that headache is dizzy.The continuous blood pressure that detects for three times, all in 195/105mmHg left and right, is diagnosed as hypertension.Eat Chinese medicine composition of the present invention every day, and after 30 days, after testing, blood pressure is reduced to 165/95mmHg, continues to eat, and after half a year, finds, blood pressure is reduced to 155/85mmHg.
Claims (2)
1. the Chinese medicine composition of a blood pressure lowering, blood fat reducing, it is characterized in that: described Chinese medicine composition is made up of root of Paeonia suffruticosa Ardr., Radix Salviae Miltiorrhizae, fresh Herba Artemisiae Annuae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, the Radix Rehmanniae, Semen Cassiae and Cortex Lycii, and the parts by weight of preparing the required each component of Chinese medicine composition are respectively root of Paeonia suffruticosa Ardr. 5-7 part, Radix Salviae Miltiorrhizae 10-15 part, fresh Herba Artemisiae Annuae 5-6 part, Spica Prunellae 6-10 part, Folium Ginkgo 10-20 part, Rhizoma Gastrodiae 8-15 part, Radix Rehmanniae 5-10 part, Semen Cassiae 10-12 part, Cortex Lycii 10-15 part.
2. the preparation method of a kind of blood pressure lowering according to claim 1, Chinese medicinal composition for reducing blood fat, is characterized in that, comprises the following steps:
Step 1, take each component by the parts by weight of each component described in claim 1, each component is put into respectively to mortar and grind, and be crushed to 30 orders, for subsequent use;
It is the reactor that 20-25 DEG C, pressure are 0.2-0.3MPa that step 2, fresh Herba Artemisiae Annuae prepared by step 1 and the Radix Rehmanniae are put into temperature, and insulation 2-3h, makes mixture I, for subsequent use;
Step 3, mixture I and root of Paeonia suffruticosa Ardr. are put into temperature is that the Rotary Evaporators of 55 DEG C is concentrated, until solid content reaches 14 ° of Brix, makes mixture II, for subsequent use;
Step 4, Radix Salviae Miltiorrhizae, Spica Prunellae, Folium Ginkgo, Rhizoma Gastrodiae, Cortex Lycii, Semen Cassiae and mixture II are put into temperature is that the baking oven of 65 DEG C is dried, then pulverize and cross 40 mesh sieves, it is that 0.095MPa, temperature are the dry 1h of vacuum desiccator of 65 DEG C that each component after pulverizing is placed in respectively to vacuum, afterwards dried each component being put into respectively to high-frequency vibration mill pulverizes, make its particle diameter reach 22 μ m, for subsequent use;
Step 5, the each component after pulverizing is mixed and stirred and makes the Chinese medicine composition of blood pressure lowering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410426759.6A CN104147393A (en) | 2014-08-27 | 2014-08-27 | Traditional Chinese composition capable of recuing blood pressure and blood lipid and preparation method thereof |
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| CN201410426759.6A CN104147393A (en) | 2014-08-27 | 2014-08-27 | Traditional Chinese composition capable of recuing blood pressure and blood lipid and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840605A (en) * | 2015-05-26 | 2015-08-19 | 合肥丰瑞隆生物科技有限公司 | Antihypertensive traditional Chinese medicine |
| CN108686113A (en) * | 2018-08-15 | 2018-10-23 | 佛山市三水区嘉华化学研究院（普通合伙） | A kind of composition and preparation method thereof for alleviating three high diseases shape |
-
2014
- 2014-08-27 CN CN201410426759.6A patent/CN104147393A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 刘晓华: "牡丹根加工丹皮", 《农村百事通》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840605A (en) * | 2015-05-26 | 2015-08-19 | 合肥丰瑞隆生物科技有限公司 | Antihypertensive traditional Chinese medicine |
| CN108686113A (en) * | 2018-08-15 | 2018-10-23 | 佛山市三水区嘉华化学研究院（普通合伙） | A kind of composition and preparation method thereof for alleviating three high diseases shape |
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Application publication date: 20141119 |
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