CN104146197A - Jelly powder for invigorating stomach and improving digestion of infants and preparation method of jelly powder - Google Patents

Jelly powder for invigorating stomach and improving digestion of infants and preparation method of jelly powder Download PDF

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Publication number
CN104146197A
CN104146197A CN201410354587.6A CN201410354587A CN104146197A CN 104146197 A CN104146197 A CN 104146197A CN 201410354587 A CN201410354587 A CN 201410354587A CN 104146197 A CN104146197 A CN 104146197A
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China
Prior art keywords
powder
jelly
gizzard
chicken
membrane
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CN201410354587.6A
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Chinese (zh)
Inventor
李军红
张爱均
李樱
李秀凤
毕丽娟
李海燕
李傑
宋骁
伊娜
张京华
周广涛
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SHANDONG HONGJITANG PHARMACEUTICAL CO Ltd
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SHANDONG HONGJITANG PHARMACEUTICAL CO Ltd
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Priority to CN201410354587.6A priority Critical patent/CN104146197A/en
Publication of CN104146197A publication Critical patent/CN104146197A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L21/00Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • A23L21/10Marmalades; Jams; Jellies; Other similar fruit or vegetable compositions; Simulated fruit products
    • A23L21/15Marmalades; Jams; Jellies; Other similar fruit or vegetable compositions; Simulated fruit products derived from fruit or vegetable juices
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses jelly powder for invigorating stomach and improving digestion of infants and a preparation method of the jelly powder. The jelly powder comprises a traditional Chinese medicine combination and other auxiliary materials which are jointly prepared into powder or granular preparation. The preparation method of the jelly powder comprises the following steps: adding water for dissolving the powder or granules, stirring and cooling to prepare the jelly. The traditional Chinese medicine combination comprises endothelium corneum gigeriae galli, hawthorn, wheat sprout or rice sprout and pericarpium citri reticulatae. The jelly powder has the functions of invigorating stomach and improving digestion; after being brewed by adding water and cooled, the jelly powder has special taste of the common jelly.

Description

A kind of children's's stomach strengthening and digestion promoting jelly powder and preparation method thereof
Technical field
The present invention relates to a kind of jelly powder, particularly relate to a kind of children's's stomach strengthening and digestion promoting jelly powder and preparation method thereof.
Background technology
Children's is due to taste hypoplasia, easily causes abdominal distension, feels sick, the indigestion symptom such as apocleisis, if children's indigestion will directly affect the absorption of nutrition, thereby affects child's growth.Majority for children's's stomach strengthening and digestion promoting is tablet, granule etc. at present, lacks the pharmaceutical dosage form that is applicable to child administration.
Jelly also claims gel, is semi-solid, and bright in colour, mouthfeel is smooth, fresh and sweet moistens, and is a kind of food of high dietary-fiber low in calories.Deeply be subject in recent years especially liking of teenager and children of consumers in general.
How medicinal for children's, in conjunction with jelly formulation advantage, provide a kind of medicament of new stomach strengthening and digestion promoting, be the problem to be solved in the present invention.
Summary of the invention
Object of the present invention provides a kind of children's's stomach strengthening and digestion promoting jelly powder and preparation method thereof for the problems referred to above exactly.The effect of the existing stomach strengthening and digestion promoting of jelly powder of the present invention, after adding water punching and cooling, has again unique mouthfeel of common jelly.
A kind of children's's stomach strengthening and digestion promoting jelly powder of the present invention and preparation method thereof technical scheme is, comprise that Chinese medicine composition and other auxiliary materials are prepared into powder or granular preparation, after being dissolved in water, stirring, placing, become jelly, Chinese medicine comprises the membrane of a chicken's gizzard, hawthorn, Fructus Hordei Germinatus or rice sprout, dried orange peel.
Described auxiliary material, comprises at least one in carragheen, konjac glucomannan, gelatin, agar, xanthans, sodium alginate.
Described auxiliary material also comprises flavouring, and flavouring comprises at least one in sweetener and aromatic.
Sweetener is at least one in sucrose, simple syrup, syrupus aromaticus, stevioside, sorbierite, saccharin sodium, sweet mellow wine, protein sugar; Aromatic is at least one in natural perfume material, essence.
Chinese medicine composition comprises following composition by weight: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus or rice sprout 60-180 part.Described Fructus Hordei Germinatus or rice sprout can be thought parched medicinal material, can be also processed product not.The described the membrane of a chicken's gizzard is frying.
Chinese medicine composition also comprises at least one in following composition by weight: Chinese yam 150-200 part, radix pseudostellariae 200-250 part, radish seed 20-30 part, Medicated Leaven 70-130 part, betel nut 20-45 part.
Chinese medicine composition comprises following composition by weight:
The membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus 60-180 part, Chinese yam 150-200 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus 60-180 part, radix pseudostellariae 200-250 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus 60-180 part, Chinese yam 150-200 part, radix pseudostellariae 200-250 part, radish seed 20-30 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus 60-180 part, Medicated Leaven 70-130 part, betel nut 20-45 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, rice sprout 60-180 part, radish seed 20-30 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, rice sprout 60-180 part, Medicated Leaven 70-130 part, betel nut 20-45, Chinese yam 150-200 part, radix pseudostellariae 200-250 part.
The preparation method of described a kind of children's's stomach strengthening and digestion promoting jelly powder, comprises the following steps:
(1) the membrane of a chicken's gizzard, the lixiviate of Fructus Hordei Germinatus temperature are got to rear filtration, other Chinese medicine boilings, filter decocting liquid, and merging filtrate is concentrated, makes dry cream, pulverizes, and obtains the powder of pharmaceutically active substance;
(2) powder step (1) being obtained adds auxiliary materials and mixing, and particle processed if desired must be containing jelly powder or the particle of pharmaceutically active substance;
(3) powder step (2) being obtained or particle add 90 ℃ of above water, stir evenly fast, after cooling jelly.
Specifically comprise the following steps:
(1) the membrane of a chicken's gizzard, Fructus Hordei Germinatus or the lixiviate of rice sprout temperature are got to secondary, each 2 hours, amount of water was 10 times of amounts of whole medicinal material weight for the first time, and amount of water is 8 times of amounts of whole medicinal material weight for the second time, merged immersion liquid, filtered; Other Chinese medicine boilings 2 times, each 2 hours, amount of water was 10 times of amounts of whole medicinal material weight for the first time, and amount of water is 8 times of amounts of whole medicinal material weight for the second time, and collecting decoction filters; Filtrate merges, concentrated, makes dry cream, pulverizes, and obtains the powder of pharmaceutically active substance;
(2) powder step (1) being obtained adds auxiliary materials and mixing, and particle processed if desired must be containing jelly powder or the particle of pharmaceutically active substance;
(3) powder step (2) being obtained or particle add 90 ℃ of above water, stir evenly fast, after cooling jelly.
Auxiliary material in step (2) comprises at least one in carragheen, konjac glucomannan, gelatin, agar, xanthans etc.; And the two or more mixture in calcium chloride, potassium chloride, sucrose, glucose, protein sugar, citric acid, potassium sorbate, water etc.
Beneficial effect of the present invention is: helping digestion of baby composition is comprised of hawthorn, Fructus Hordei Germinatus, Divine Comedy, the membrane of a chicken's gizzard, betel nut, dried orange peel, radix pseudostellariae, radish seed, Chinese yam etc.Hawthorn can disappear carnivorous long-pending, food digesting stomach fortifying; The Fructus Hordei Germinatus wheaten food that can disappear is long-pending, again can strengthening the spleen and stomach; It is long-pending that Divine Comedy can be changed place, and in spleen tune; The membrane of a chicken's gizzard helps digestion to grind and amasss, kindization combined symptoms; It is stagnant that betel nut declares the sharp vital organs of the human body to stop up, and the capable water of sending down abnormally ascending again can expelling parasite; Dried orange peel has regulating qi-flowing for eliminating phlegm, and the effect of stomach preventing or arresting vomiting; Radix pseudostellariae has invigorating qi and benefiting blood, promotes the production of body fluid, the effect of tonifying spleen and stomach; Radish seed tells wind phlegm, and dispersing wind and cold is determined asthma due to excessive phlegm cough, and main lower gasification is stagnant; Chinese yam contains the materials such as amylase, polyphenol oxidase, is conducive to taste digestion and absorption function, is the product of the medicine-food two-purpose of flat tonifying spleen and stomach simply.According to above compatibility, we have relieving dyspepsia, the merit of the dissipate-swelling of regulating the flow of vital energy.
Jelly powder of the present invention has the effect of stomach strengthening and digestion promoting, can effectively strengthen children's's appetite, has no side effect, after adding water punching and cooling, bright in colour, mouthfeel is smooth, fresh and sweet moistens, and meets especially liking of juvenile of consumers in general, is a kind of stomach strengthening and digestion promoting preparation of uniqueness.
the specific embodiment:
In order to understand better the present invention, with instantiation, describe technical scheme of the present invention in detail below.
embodiment 1
For a jelly powder for children's's stomach strengthening and digestion promoting, by the following weight proportion Chinese medicine composition with food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 10g, hawthorn 150g, dried orange peel 20g, Fructus Hordei Germinatus 150g, auxiliary material adds konjac glucomannan 8g, carragheen 3g, citric acid 0.50g, sucrose 100g, CaC1 20.50g, potassium sorbate 0.30g, makes jelly powder.
The preparation flow of the present embodiment is as follows:
The first step, assorts Chinese medicine by aforementioned Chinese medicinal formulae, according to Chinese pharmacopoeia medicinal material processing standard, all Chinese medicine preparations are qualified;
Second step, carries out aseptic process to all Chinese medicines;
The 3rd step, gets secondary by the membrane of a chicken's gizzard, the lixiviate of Fructus Hordei Germinatus temperature, and each 2 hours, amount of water was 10 times of amounts of whole medicinal material weight for the first time, and amount of water is 8 times of amounts of whole medicinal material weight for the second time, merges immersion liquid, filters; Other Chinese medicine boilings 2 times, each 2 hours, amount of water was 10 times of amounts of whole medicinal material weight for the first time, and amount of water is 8 times of amounts of whole medicinal material weight for the second time, and collecting decoction filters; Filtrate merges, concentrated, makes dry cream, pulverizes, and obtains the powder of pharmaceutically active substance;
The 4th step, this active material adds auxiliary materials and mixing, obtains mixed-powder or granulates if desired.Auxiliary material of the present invention comprises konjac glucomannan 8g, carragheen 3g, citric acid 0.50g, sucrose 100g, CaC1 20.50g, potassium sorbate 0.30g.
The 5th step, mixes the particle making, powder or other forms of material, pack, packing.Sample A, sample A adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample A meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.
drug efficacy study result
1. pair mouse small intestine propulsion trial: result is as shown in table 1, experimental result shows, to mouse small intestine, motion has significant enhancing progradation to the large, medium and small dosage of helping digestion of baby composition, middle dosage and digestion-promoting stomachic are suitable, low dose of act on not remarkable.
Table 1
2. cholagogic test: result is as shown in table 2, shows that helping digestion of baby composition multiple dosing has obvious choleretic effect to rat.
Table 2
3. hydrochloric acid in gastric juice and pepsin determination test result are as shown in table 3, show that helping digestion of baby composition is known to dog gastric juice pepsin unit measurement result, and helping digestion of baby composition and digestion-promoting stomachic all can significantly promote the pepsic secretion of dog.
Table 3
With physiological saline control group than the P<0.01 of * *.
This time research shows that helping digestion of baby composition has the regulate the flow of vital energy effect of dissipate-swelling of helping digestion Zhi ﹑, for its clinical practice provides experimental basis.
toxicological study result
The experiment of helping digestion of baby composition maximal tolerance dose is with the Cmax (60%) of suspension, maximum volume (0.2ml/10g) is given mouse stomach, every day 3 times, then Continuous Observation is 7 days, have no obvious toxic reaction, helping digestion of baby composition maximal tolerance dose is equivalent to clinical 360 times by kg body weight conversion, has no obvious toxic reaction.
Known according to above test, helping digestion of baby composition quantity is safer.
embodiment 2
For a jelly powder for children's's stomach strengthening and digestion promoting, by the following weight proportion Chinese medicine composition with food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 6g, hawthorn 100g, dried orange peel 10g, Fructus Hordei Germinatus 135g, Chinese yam 170g, auxiliary material adds carragheen 6g, agar 3g, citric acid 0.50g, sucrose 80g, CaC1 20.40g, potassium sorbate 0.30g, makes jelly powder.
Preparation method is with embodiment 1.Wherein Chinese yam processing method is with the medicinal material except the membrane of a chicken's gizzard, Fructus Hordei Germinatus.Sample B, sample B adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample B meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
chinese yam discrimination test:
Get this product 50g 100ml that adds methylene chloride, add hot reflux 2 hours, filter, filtrate evaporate to dryness, the residue 1ml that adds methylene chloride makes to dissolve, as need testing solution; Separately get Chinese yam control medicinal material 5g, be made in the same way of control medicinal material solution.
According to thin-layered chromatography appendix VI B, test, draw above-mentioned two kinds of each 4ul of solution, put respectively on same silica gel g thin-layer plate, take ethyl acetate-methyl alcohol-strong ammonia solution volume ratio as 9:1:0.5 be solvent, launch to take out, airing, spray, with 10% phosphomolybdic acid ethanol solution, is heated to spot colour developing at 105 ℃ clear.
In test sample chromatogram, be the spot of aobvious same color on the corresponding position of control medicinal material chromatogram.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.
 
embodiment 3
For a jelly powder for children's's stomach strengthening and digestion promoting, by the Chinese medicine composition with the following weight proportion of food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 6g, hawthorn 100g, dried orange peel 10g, Fructus Hordei Germinatus 135g, radix pseudostellariae 220g.Auxiliary material adds carragheen 10g, agar 4g, citric acid 0.80g, sucrose 100g, CaC1 20.60g, potassium sorbate 0.40g, makes jelly powder.
Preparation method is with embodiment 1.Wherein radix pseudostellariae processing method is with other traditional Chinese medicine ingredients except the membrane of a chicken's gizzard, Fructus Hordei Germinatus.Sample C, sample C adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample C meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
radix pseudostellariae discrimination test:
Get this product 50g and add methyl alcohol 100ml, add hot reflux 30min, filter, filtrate evaporate to dryness, residue adds water 40ml to be made to dissolve, by the large empty adsorption resin column of D101 type, water 200ml wash-out, discard water lotion, use again ethanol 100ml wash-out, collect ethanol eluate, evaporate to dryness, residue adds methyl alcohol 1ml to be made to dissolve, as need testing solution; Separately get radix pseudostellariae control medicinal material 5g, boiling 2 hours, centrifugal, get supernatant, by the large empty adsorption resin column of D101 type, be made in the same way of control medicinal material solution.
According to thin-layered chromatography appendix VI B test, draw above-mentioned two kinds of each 20ul of solution, put respectively on same silica gel g thin-layer plate, take toluene-ethyl acetate volume ratio as 4:1 be solvent, launch to take out airing, spray, with 1% vanillic aldehyde sulfuric acid solution, is heated to spot colour developing at 105 ℃ clear.
In test sample chromatogram, be the spot of aobvious same color on the corresponding position of control medicinal material chromatogram.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.
embodiment 4
For a jelly powder for children's's stomach strengthening and digestion promoting, by the Chinese medicine composition with the following weight proportion of food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 6g, hawthorn 100g, dried orange peel 10g, Fructus Hordei Germinatus 135g, Chinese yam 170g, radix pseudostellariae 220g, radish seed 25g.Auxiliary material adds xanthans 12g, sodium alginate 5g, agar 5g, citric acid 0.50g, sucrose 120g, CaC1 20.40g, potassium sorbate 0.30g, make jelly powder.
Preparation method is with embodiment 1.Wherein radix pseudostellariae, Chinese yam, radish seed processing method are with other traditional Chinese medicine ingredients except the membrane of a chicken's gizzard, Fructus Hordei Germinatus.Sample D, sample D adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample D meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
radix pseudostellariae discrimination test:
Get this product 50g and add methyl alcohol 100ml, add hot reflux 30min, filter, filtrate evaporate to dryness, residue adds water 40ml to be made to dissolve, by the large empty adsorption resin column of D101 type, water 200ml wash-out, discard water lotion, use again ethanol 100ml wash-out, collect ethanol eluate, evaporate to dryness, residue adds methyl alcohol 1ml to be made to dissolve, as need testing solution; Separately get radix pseudostellariae control medicinal material 5g, boiling 2 hours, centrifugal, get supernatant, by the large empty adsorption resin column of D101 type, be made in the same way of control medicinal material solution.
According to thin-layered chromatography appendix VI B test, draw above-mentioned two kinds of each 20ul of solution, put respectively on same silica gel g thin-layer plate, take toluene-ethyl acetate volume ratio as 4:1 be solvent, launch to take out airing, spray, with 1% vanillic aldehyde sulfuric acid solution, is heated to spot colour developing at 105 ℃ clear.
In test sample chromatogram, be the spot of aobvious same color on the corresponding position of control medicinal material chromatogram.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.
embodiment 5
For a jelly powder for children's's stomach strengthening and digestion promoting, by the Chinese medicine composition with the following weight proportion of food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 6g, hawthorn 124g, dried orange peel 10g, Fructus Hordei Germinatus 114g, Medicated Leaven 114g, betel nut 31g.Auxiliary material comprises xanthans 12g, sodium alginate 7g, agar 5g, citric acid 0.40g, sucrose 100g, CaC120.50g, potassium sorbate 0.35g, makes jelly powder.
Preparation method is with embodiment 1.Wherein Medicated Leaven, betel nut processing method are with other traditional Chinese medicine ingredients except the membrane of a chicken's gizzard, Fructus Hordei Germinatus.Sample E, sample E adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample E meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
betel nut discrimination test:
Get this product 25g, porphyrize, adds chloroform 100ml and liquor ammoniae fortis 12ml, ultrasonic processing 15 minutes, filters, and filtrate is placed in separatory funnel, add 20% hydrochloric acid solution 50ml, jolting, divides and gets sour water layer, add strong ammonia solution and adjust pH value approximately 9, with chloroform jolting, extract 2 times, each 40ml, merge chloroform liquid, naturally volatilize, residue adds methyl alcohol 0.5ml to be made to dissolve, as need testing solution.Separately get betel nut control medicinal material 2g, be made in the same way of control medicinal material solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 10 l of above-mentioned two kinds of solution, put respectively on same silica gel g thin-layer plate, chloroform-methyl alcohol-ammoniacal liquor the volume ratio (92:8:1) of take is solvent, launch, take out, dry, spray is with rare bismuth potassium iodide test solution.In test sample chromatogram, with the corresponding position of control medicinal material chromatogram on, aobvious identical Chinese red spot.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.
embodiment 6
For a jelly powder for children's's stomach strengthening and digestion promoting, by the following weight proportion Chinese medicine composition with food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 8g, hawthorn 120g, dried orange peel 12g, rice sprout 150g, radish seed 25g.Auxiliary material comprises xanthans 10g, sodium alginate 5g, agar 5g, citric acid 0.40g, sucrose 80g, CaC120.35g, potassium sorbate 0.35g, makes jelly powder.
Preparation method is with embodiment 1.Wherein radish seed processing method is with other traditional Chinese medicine ingredients except the membrane of a chicken's gizzard, rice sprout.Sample F, sample F adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample F meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.
embodiment 7
For a jelly powder for children's's stomach strengthening and digestion promoting, by the following weight proportion Chinese medicine composition with food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 8g, hawthorn 120g, dried orange peel 12g, rice sprout 150g, Medicated Leaven 120g, betel nut 30g, Chinese yam 180g, radix pseudostellariae 220g.Auxiliary material comprises xanthans 20g, sodium alginate 10g, agar 10g, citric acid 1.0g, sucrose 150g, CaC120.80g, potassium sorbate 0.50g, makes jelly powder.
Preparation method is with embodiment 1.Wherein radix pseudostellariae, Chinese yam processing method are with other traditional Chinese medicine ingredients except the membrane of a chicken's gizzard, rice sprout.Sample G, sample G adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample G meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
radix pseudostellariae discrimination test:
Get this product 50g and add methyl alcohol 100ml, add hot reflux 30min, filter, filtrate evaporate to dryness, residue adds water 40ml to be made to dissolve, by the large empty adsorption resin column of D101 type, water 200ml wash-out, discard water lotion, use again ethanol 100ml wash-out, collect ethanol eluate, evaporate to dryness, residue adds methyl alcohol 1ml to be made to dissolve, as need testing solution; Separately get radix pseudostellariae control medicinal material 5g, boiling 2 hours, centrifugal, get supernatant, by the large empty adsorption resin column of D101 type, be made in the same way of control medicinal material solution.
According to thin-layered chromatography appendix VI B test, draw above-mentioned two kinds of each 20ul of solution, put respectively on same silica gel g thin-layer plate, take toluene-ethyl acetate volume ratio as 4:1 be solvent, launch to take out airing, spray, with 1% vanillic aldehyde sulfuric acid solution, is heated to spot colour developing at 105 ℃ clear.
In test sample chromatogram, be the spot of aobvious same color on the corresponding position of control medicinal material chromatogram.
betel nut discrimination test:
Get this product 25g, porphyrize, adds chloroform 100ml and liquor ammoniae fortis 12ml, ultrasonic processing 15 minutes, filters, and filtrate is placed in separatory funnel, add 20% hydrochloric acid solution 50ml, jolting, divides and gets sour water layer, add strong ammonia solution and adjust pH value approximately 9, with chloroform jolting, extract 2 times, each 40ml, merge chloroform liquid, naturally volatilize, residue adds methyl alcohol 0.5ml to be made to dissolve, as need testing solution.Separately get betel nut control medicinal material 2g, be made in the same way of control medicinal material solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 10 l of above-mentioned two kinds of solution, put respectively on same silica gel g thin-layer plate, chloroform-methyl alcohol-ammoniacal liquor the volume ratio (92:8:1) of take is solvent, launch, take out, dry, spray is with rare bismuth potassium iodide test solution.In test sample chromatogram, with the corresponding position of control medicinal material chromatogram on, aobvious identical Chinese red spot.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.
Skin glycosides is no less than 0.15mg.
embodiment 8
For a jelly powder for children's's stomach strengthening and digestion promoting, by the Chinese medicine composition with the following weight proportion of food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 2g, hawthorn 80g, dried orange peel 24g, Fructus Hordei Germinatus 170g, Medicated Leaven 70g, betel nut 25g.Auxiliary material comprises xanthans 25g, sodium alginate 10g, citric acid 1.00g, sucrose 120g, CaC1 20.80g, potassium sorbate 0.50g, make jelly powder.
Preparation method is with embodiment 1.Wherein Medicated Leaven, betel nut processing method are with other traditional Chinese medicine ingredients except the membrane of a chicken's gizzard, Fructus Hordei Germinatus.Sample H, sample H adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample H meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
betel nut discrimination test:
Get this product 25g, porphyrize, adds chloroform 100ml and liquor ammoniae fortis 12ml, ultrasonic processing 15 minutes, filters, and filtrate is placed in separatory funnel, add 20% hydrochloric acid solution 50ml, jolting, divides and gets sour water layer, add strong ammonia solution and adjust pH value approximately 9, with chloroform jolting, extract 2 times, each 40ml, merge chloroform liquid, naturally volatilize, residue adds methyl alcohol 0.5ml to be made to dissolve, as need testing solution.Separately get betel nut control medicinal material 2g, be made in the same way of control medicinal material solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 10 l of above-mentioned two kinds of solution, put respectively on same silica gel g thin-layer plate, chloroform-methyl alcohol-ammoniacal liquor the volume ratio (92:8:1) of take is solvent, launch, take out, dry, spray is with rare bismuth potassium iodide test solution.In test sample chromatogram, with the corresponding position of control medicinal material chromatogram on, aobvious identical Chinese red spot.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.
embodiment 9
For a jelly powder for children's's stomach strengthening and digestion promoting, by the Chinese medicine composition with the following weight proportion of food digesting stomach fortifying function, formed: the membrane of a chicken's gizzard 10g, hawthorn 140g, dried orange peel 6g, Fructus Hordei Germinatus 170g, radix pseudostellariae 250g.Auxiliary material adds carragheen 15g, agar 3g, konjac glucomannan 5g citric acid 0.80g, sucrose 120g, CaC1 20.60g, potassium sorbate 0.50g, makes jelly powder.
Preparation method is with embodiment 1.Wherein radix pseudostellariae processing method is with other traditional Chinese medicine ingredients except the membrane of a chicken's gizzard, Fructus Hordei Germinatus.Sample I, sample I adds 90 ℃ of above water, stir evenly fast, after cooling jelly.
Sample I meets the requirement such as outward appearance, moisture, loading amount, microorganism under < < Chinese pharmacopoeia > > version appendix I powder in 2010 or granule item through quality testing.
aurantiamarin discrimination test:
Get this product 5g, porphyrize, adds methyl alcohol 20ml, and ultrasonic processing 30min filters, and filtrate is concentrated into 2ml, as need testing solution.Separately get aurantiamarin reference substance, add methyl alcohol and make saturated solution, in contrast product solution.According to thin-layered chromatography (appendix VI B of Chinese pharmacopoeia version in 2010), test, draw each 5 l of above-mentioned two kinds of solution, put respectively on the silica gel g thin-layer plate of preparing in same use 1% sodium hydroxide solution, ethyl acetate-methanol-water the volume ratio (100:17:13) of take is solvent, exhibition is apart from about 4cm, take out, dry, the upper solution of toluene-ethyl acetate-formic acid-water volume ratio (20:10:1:1) of take is again solvent, exhibition, apart from about 10cm, is taken out, and dries, spray, with alchlor test solution, is put under ultraviolet lamp (365nm) and is inspected.In test sample chromatogram, with the corresponding position of reference substance chromatogram on, the fluorescence spot of aobvious same color.
radix pseudostellariae discrimination test:
Get this product 50g and add methyl alcohol 100ml, add hot reflux 30min, filter, filtrate evaporate to dryness, residue adds water 40ml to be made to dissolve, by the large empty adsorption resin column of D101 type, water 200ml wash-out, discard water lotion, use again ethanol 100ml wash-out, collect ethanol eluate, evaporate to dryness, residue adds methyl alcohol 1ml to be made to dissolve, as need testing solution; Separately get radix pseudostellariae control medicinal material 5g, boiling 2 hours, centrifugal, get supernatant, by the large empty adsorption resin column of D101 type, be made in the same way of control medicinal material solution.
According to thin-layered chromatography appendix VI B test, draw above-mentioned two kinds of each 20ul of solution, put respectively on same silica gel g thin-layer plate, take toluene-ethyl acetate volume ratio as 4:1 be solvent, launch to take out airing, spray, with 1% vanillic aldehyde sulfuric acid solution, is heated to spot colour developing at 105 ℃ clear.
In test sample chromatogram, be the spot of aobvious same color on the corresponding position of control medicinal material chromatogram.
assay test:
Ursolic acid content in sample is measured, and every bag is no less than 0.20mg containing ursolic acid.
Content of hesperidin is measured, and every bag is no less than 0.15mg containing aurantiamarin.

Claims (10)

1. children's's stomach strengthening and digestion promoting jelly powder, is characterized in that, comprises Chinese medicine composition and other auxiliary materials, is jointly prepared into powder or granular preparation; This powder or particle become jelly after being dissolved in water, stirring, cooling, and contained Chinese medicine composition comprises the membrane of a chicken's gizzard, hawthorn, Fructus Hordei Germinatus or rice sprout, dried orange peel.
2. a kind of children's's stomach strengthening and digestion promoting jelly powder according to claim 1, is characterized in that described auxiliary material comprises at least one in carragheen, konjac glucomannan, gelatin, agar, xanthans, sodium alginate.
3. a kind of children's's stomach strengthening and digestion promoting jelly powder according to claim 2, is characterized in that, described auxiliary material also comprises flavouring, and flavouring comprises at least one in sweetener and aromatic.
4. a kind of children's's stomach strengthening and digestion promoting jelly powder according to claim 3, is characterized in that, sweetener is at least one in sucrose, simple syrup, syrupus aromaticus, stevioside, sorbierite, saccharin sodium, sweet mellow wine, protein sugar; Aromatic is at least one in natural perfume material, essence.
5. a kind of children's's stomach strengthening and digestion promoting jelly powder according to claim 1, is characterized in that, Chinese medicine composition comprises following composition by weight: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus or rice sprout 60-180 part.
6. a kind of children's's stomach strengthening and digestion promoting jelly powder according to claim 5, it is characterized in that, Chinese medicine composition also comprises at least one in following composition by weight: Chinese yam 150-200 part, radix pseudostellariae 200-250 part, radish seed 20-30 part, Medicated Leaven 70-130 part, betel nut 20-45 part.
7. a kind of children's's stomach strengthening and digestion promoting jelly powder according to claim 6, is characterized in that, Chinese medicine composition comprises following composition by weight:
The membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus 60-180 part, Chinese yam 150-200 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus 60-180 part, radix pseudostellariae 200-250 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus 60-180 part, Chinese yam 150-200 part, radix pseudostellariae 200-250 part, radish seed 20-30 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, Fructus Hordei Germinatus 60-180 part, Medicated Leaven 70-130 part, betel nut 20-45 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, rice sprout 60-180 part, radish seed 20-30 part;
Or be: the membrane of a chicken's gizzard 2-10 part, hawthorn 80-150 part, dried orange peel 6-25 part, rice sprout 60-180 part, Medicated Leaven 70-130 part, betel nut 20-45, Chinese yam 150-200 part, radix pseudostellariae 200-250 part.
8. the preparation method of a kind of children's's stomach strengthening and digestion promoting jelly powder as claimed in claim 1, is characterized in that, comprises the following steps:
(1) the membrane of a chicken's gizzard, the lixiviate of Fructus Hordei Germinatus temperature are got to rear filtration, other Chinese medicine composition boilings, filter decocting liquid, and merging filtrate is concentrated, makes dry cream, pulverizes, and obtains the powder of pharmaceutically active substance;
(2) powder step (1) being obtained adds auxiliary materials and mixing, and particle processed, obtains pastille jelly powder or particle if desired;
(3) powder step (2) being obtained or particle add 90 ℃ of above water, stir evenly fast, after cooling jelly.
9. the preparation method of a kind of children's's stomach strengthening and digestion promoting jelly powder according to claim 8, is characterized in that, comprises the following steps:
(1) the membrane of a chicken's gizzard, the lixiviate of Fructus Hordei Germinatus temperature are got to secondary, each 2 hours, amount of water was 10 times of amounts of whole medicinal material weight for the first time, and amount of water is 8 times of amounts of whole medicinal material weight for the second time, and collecting decoction filters; All the other medicinal material boilings 2 times, each 2 hours, amount of water was 10 times of amounts of whole medicinal material weight for the first time, and amount of water is 8 times of amounts of whole medicinal material weight for the second time, and collecting decoction filters; Filtrate and decocting liquid merge, concentrated, make dry cream, pulverize, and obtain the powder of pharmaceutically active substance;
(2) powder step (1) being obtained adds auxiliary materials and mixing, and particle processed, obtains pastille jelly powder or particle if desired;
(3) powder step (2) being obtained or particle add 90 ℃ of above water, stir evenly fast, after cooling jelly.
10. the preparation method of a kind of children's's stomach strengthening and digestion promoting jelly powder according to claim 8, is characterized in that, the auxiliary material in step (2) comprises at least one in carragheen, konjac glucomannan, gelatin, agar, xanthans etc.; And the two or more mixture in calcium chloride, potassium chloride, sucrose, glucose, protein sugar, citric acid, potassium sorbate, water etc.
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CN104522447A (en) * 2014-12-18 2015-04-22 南方医科大学 Jelly with effects of improving appetite and promoting digestion suitable for being taken by children
CN104522444A (en) * 2014-12-01 2015-04-22 张旭 Jelly capable of stimulating appetite and promoting digestion
CN104783024A (en) * 2015-04-01 2015-07-22 广西大学 Compound-flavor roselle jelly powder
CN104872482A (en) * 2015-05-27 2015-09-02 台州科技职业学院 Health jelly and preparation method thereof
CN105194453A (en) * 2015-10-30 2015-12-30 曲姮 Traditional Chinese medicine preparation for treating child food retention
CN105707792A (en) * 2016-03-15 2016-06-29 安徽九禾农业发展有限公司 Appetite-improving and digestion-promoting sauce with grapes as carrier and preparation method thereof
CN105795410A (en) * 2016-03-15 2016-07-27 安徽九禾农业发展有限公司 Digestion-promoting jelly utilizing grapes as main part and preparation method thereof
CN106110091A (en) * 2016-07-22 2016-11-16 胡彬 A kind of invigorating the stomach and promoting digestion cream and preparation method thereof
CN106174281A (en) * 2016-07-22 2016-12-07 广东农工商职业技术学院 A kind of wine fruit jelly and preparation method thereof
CN106490479A (en) * 2016-10-31 2017-03-15 崔子扬 A kind of draft skin care pudding powder and preparation method thereof
CN107997176A (en) * 2018-01-30 2018-05-08 郑州万家食品有限公司 A kind of stomach strengthening and digestion promoting health food for preventing children's having indigestion apocleisis
CN109832592A (en) * 2018-05-02 2019-06-04 江西中医药大学 A kind of reinforcing spleen to promote digestion appetizing jelly and preparation method thereof
CN109907268A (en) * 2019-04-22 2019-06-21 厦门市中萪研生物科技有限公司 A kind of taste are inhaled and preparation method thereof
CN110558505A (en) * 2019-08-21 2019-12-13 合肥师范学院 Method for making chicken's gizzard-membrane haw jelly
CN110584047A (en) * 2019-09-30 2019-12-20 佛山科学技术学院 Spleen-tonifying and appetite-promoting jelly and preparation method thereof
CN111134304A (en) * 2019-12-02 2020-05-12 广东一方制药有限公司 Stomach-invigorating and digestion-promoting jelly and preparation method thereof
CN111743082A (en) * 2020-07-06 2020-10-09 重庆医药高等专科学校 Dietary therapy formula for treating infantile spleen deficiency and anorexia and preparation method thereof
CN111955696A (en) * 2020-09-07 2020-11-20 绿色田园(衡阳)农业发展有限公司 Dried loquat and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN104472976A (en) * 2014-12-01 2015-04-01 张旭 Jelly with health preserving and health caring functions
CN104522444A (en) * 2014-12-01 2015-04-22 张旭 Jelly capable of stimulating appetite and promoting digestion
CN104522447A (en) * 2014-12-18 2015-04-22 南方医科大学 Jelly with effects of improving appetite and promoting digestion suitable for being taken by children
CN104783024A (en) * 2015-04-01 2015-07-22 广西大学 Compound-flavor roselle jelly powder
CN104872482A (en) * 2015-05-27 2015-09-02 台州科技职业学院 Health jelly and preparation method thereof
CN105194453A (en) * 2015-10-30 2015-12-30 曲姮 Traditional Chinese medicine preparation for treating child food retention
CN105707792A (en) * 2016-03-15 2016-06-29 安徽九禾农业发展有限公司 Appetite-improving and digestion-promoting sauce with grapes as carrier and preparation method thereof
CN105795410A (en) * 2016-03-15 2016-07-27 安徽九禾农业发展有限公司 Digestion-promoting jelly utilizing grapes as main part and preparation method thereof
CN106110091A (en) * 2016-07-22 2016-11-16 胡彬 A kind of invigorating the stomach and promoting digestion cream and preparation method thereof
CN106174281A (en) * 2016-07-22 2016-12-07 广东农工商职业技术学院 A kind of wine fruit jelly and preparation method thereof
CN106490479A (en) * 2016-10-31 2017-03-15 崔子扬 A kind of draft skin care pudding powder and preparation method thereof
CN107997176A (en) * 2018-01-30 2018-05-08 郑州万家食品有限公司 A kind of stomach strengthening and digestion promoting health food for preventing children's having indigestion apocleisis
CN109832592A (en) * 2018-05-02 2019-06-04 江西中医药大学 A kind of reinforcing spleen to promote digestion appetizing jelly and preparation method thereof
CN109907268A (en) * 2019-04-22 2019-06-21 厦门市中萪研生物科技有限公司 A kind of taste are inhaled and preparation method thereof
CN110558505A (en) * 2019-08-21 2019-12-13 合肥师范学院 Method for making chicken's gizzard-membrane haw jelly
CN110584047A (en) * 2019-09-30 2019-12-20 佛山科学技术学院 Spleen-tonifying and appetite-promoting jelly and preparation method thereof
CN111134304A (en) * 2019-12-02 2020-05-12 广东一方制药有限公司 Stomach-invigorating and digestion-promoting jelly and preparation method thereof
CN111743082A (en) * 2020-07-06 2020-10-09 重庆医药高等专科学校 Dietary therapy formula for treating infantile spleen deficiency and anorexia and preparation method thereof
CN111955696A (en) * 2020-09-07 2020-11-20 绿色田园(衡阳)农业发展有限公司 Dried loquat and preparation method thereof

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