CN1041279C

CN1041279C - Medicine for curing dermatosis

Info

Publication number: CN1041279C
Application number: CN93118020A
Authority: CN
Inventors: 栾兴志
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-10-08
Filing date: 1993-10-08
Publication date: 1998-12-23
Anticipated expiration: 2013-10-08
Also published as: CN1101269A

Abstract

The present invention relates to a medicine for treating dermatosis, which is characterized in that the medicine is prepared by extracting honeysuckle flower, phellodendron bark, radix sophorae flavescentis, cotex dictamni, dried alum, sulfur and realgar which as raw materials decocted in water. The medicine is used for treating skin pruritus, fungous diseases, scabies, urticaria, psoriasis, seborrheic dermatitis, calvities, eczema, wart and neurodermatitis. The medicine has the advantages of rapid medicine effect, lasting function, strong sterilization capability, rapid itching relieving, high curative effect and no toxic or side effect, and has the function of resisting viruses, stimulating the growth of normal cells and promoting skin metabolism.

Description

A kind of treatment dermatosis medicament

The present invention relates to a kind of treatment dermatosis medicament, be applicable to treatment skin pruritus, mycosis, scabies, urticaria, psoriasis, seborrheic dermatitis, alopecia, eczema, wart, neurodermatitis.

Dermatosis is a kind of relatively disease of intractable difficulty, it has brought a lot of inconvenience for people's live and work, it not only damages skin, influence appearance, and pruritus usually, the people is agonized unbearably more, also be infectious, adopt medicine for external use coating affected part for the treating for skin disease great majority at present, or adopt medicine for external use to mix some Western medicine Comprehensive Treatments again; Though some medicine has therapeutic effect, be difficult for thoroughly, recurrence easily, or drug dependence is arranged; Some drug dose does not have therapeutic effect after a little while, and consumption is chafe again too much; Also contain toxic component in some medicine, as Arsenicum sablimatum, Calomelas, therefore medicines such as hydrargyrum are harmful to health, produce the effect of paying.

Order of the present invention has the shortcoming and deficiency that is to overcome above-mentioned prior art existence, and provide a kind of is the strong treatment dermatosis medicament of raw material the water fried effect of paying of nontoxic nothing, curative effect height, sterilizing power with Chinese medicine, remove patient's misery thereby be situated between, get well early, better work and study.

The objective of the invention is to realize by following technical proposal:

It is that raw material refines after with decocting and gets that medicament of the present invention adopts Chinese medicine Flos Lonicerae, Cortex Phellodendri, Radix Sophorae Flavescentis, favus skin, dried Alumen, sulfur and Realgar, raw material each component consumption by weight is: Flos Lonicerae 25-50 part, Cortex Phellodendri 10-25 part, Radix Sophorae Flavescentis 10-25 part, Cortex Dictamni 10-25 part, dried Alumen 50-80 part, sulfur 10-20 part, Realgar 10-20 part, water consumption are the heavy 8-10 of raw material times, and the decocting time is 30-40 minute.

Medicament of the present invention can be made mastic or soap body with carrier.

Owing to taked technique scheme, make medicament of the present invention have property of medicine performance rapidly, effect is lasting, sterilizing power is strong, antipruritic soon, curative effect is high, can reach 94%, nontoxic nothing is paid effect, and antivirus action is arranged and stimulate Normocellular growth effect, promote the advantage and the effect of skin metabolism.

Medicament of the present invention is through clinical observation case 327 examples, male's 225 examples wherein, women's 102 examples, year made the maximum 73 years old, reckling is observed case for month baby of birth with skin pruritus, mycosis, scabies, urticaria, psoriasis, seborrheic dermatitis, alopecia, eczema, wart and neurodermatitis.

The clinical efficacy standard:

Cure: pruritus is ended, and it is normal that skin lesion recovers, and drug withdrawal is not recurrence after three months;

Produce effects: pruritus is ended, and it is normal that skin lesion recovers substantially;

Take a turn for the better: pruritus alleviates, and it is unstable, flickering that skin lesion recovers;

Invalid: medication did not have any effect in 3 days.

Clinical observation result:

Table 1

The dermatosis title	Case load	Therapeutic outcome				Total effective rate %
		Therapeutic outcome					Cure rate %	Obvious effective rate %	Improvement rate %	Inefficiency %
		Cutaneous pruritus nosomycosis scabies nettle rash psoriasis seborrhea alopecia eczema wart neurodermatitis adds up to	49 47 45 41 37 33 33 26 11 5 327	63.30 59.60 90.00 70.70 13.50 90.90 72.70 65.40 72.70 30.00 62.88	24.50 25.50 5.00 26.80 56.80 5.10 18.20 15.40 9.10 20.00 20.64		Cure rate %	Obvious effective rate %	Improvement rate %	Inefficiency %	10.20 10.60 3.00 / 21.60 / 6.10 9.20 9.10 40.00 10.98	2.00 4.30 2.00 2.50 8.10 4.00 3.00 10.00 9.10 10.00 5.50	98.00 95.70 98.00 97.50 91.90 96.00 97.00 90.00 90.90 90.00 94.50

Show that from clinical observation result medicament of the present invention is good to the sick therapeutic effect of various skin, average effectiveness level is 94.50%, property of medicine performance is antipruritic rapidly fast, and effect is lasting, thoroughly, nontoxic nothing is paid effect, and what do not heal to once using the hormones medicine for external use also has a better therapeutic effect.

Medicament property of medicine contrast and experiment of the present invention:

With medicament of the present invention is experimental group, is the controlled observation group with oxytetracycline, streptomycin, chloromycetin.Above-mentioned three kinds of antibiotics scraps of paper are provided by Harbin City medicine inspecting institute.With anti-gram negative bacteria, gram positive bacteria and fungus is object.Is the variable concentrations of stock solution (concentration) with the medicament of experimental group with normal saline dilution 10%, 20%, 40%, 60%, 80%, 100%.Strain is provided by the Applied Microbiology Inst., Heilongjiang Academy of Sciences.Be that gram negative bacteria is used escherichia coli, gram positive bacteria is used staphylococcus aureus, and fungus is tested with unusual Chinese Xun Shi female bacterium of alcohol and Aspergillus niger.

Experimental result inhibition zone occurs with plate and diameter (millimeter) size is judged effect, its result following (seeing Table 2): table 2

Observation group's drug concentration (medicament of the present invention) control group medicament strain name 10% 20% 40% 60% 80% 100% unusual Chinese of terramycin streptomysin chloramphenicol Escherichia coli-13 27 27 27 28 29 21 28 golden yellow-18 20 22 22 22 19 19 20 staphylococcus are inferior---13 13 14---family name's saccharomycete black-koji mould-12 13 15 17 17---

Property of medicine contrast and experiment shows, medicament of the present invention is diluted to 20% above concentration has stronger bacteriostasis to gram negative bacteria, wherein from 60%, 80%, 100% 3 concentration antibacterial circle diameter reaches the 27-28 millimeter, with oxytetracycline and streptomycin, the bacteriostasis of chloromycetin is (P＜0.05) quite, the blue positive bacteria of Ge Shi is reached the 18-22 millimeter from the antibacterial circle diameter of 20%-100%, obviously be better than oxytetracycline, the bacteriostasis of the antibiotics of streptomycin and chloromycetin (P＜0.01), for the rising that is directly proportional with its concentration of the bacteriostasis of fungus, concentration is anti-negative to the unusual Hansenula anomala bacterium of fungus when following 40%, 60% above concentration antibacterial circle diameter is the 13-14 millimeter, bacteriostasis to Aspergillus niger adopts 20%-100% concentration, all be positive, antibacterial circle diameter is the 12-17 millimeter, its bacteriostasis is directly proportional with the degree of depth, and oxytetracycline, streptomycin, chloromycetin does not have antibiotic effect to fungus and is negative, therefore can prove, medicament of the present invention can not only resist gram negative bacteria and gram positive bacteria, and fungus had good antibacterial property, it has the progress and the raising of highly significant than the antibiotic property of Western medicine.

Most preferred embodiment:

Extracting honeysuckle 30 gram, Cortex Phellodendri 20 grams, Radix Sophorae Flavescentis 20 grams, Cortex Dictamni 20 grams, dried Alumen 60 grams, sulfur 15 grams, Realgar 15 grams, add jar, add water 1800 grams, the temperature fire decocted 30 minutes, removed by filter medicinal residues, and promptly filtrate is medicament of the present invention.Medicament of the present invention, direct wiping affected part, every day 1-3 time, 7 days is a course of treatment.This medicament is made carrier with oils, makes paste, can be coated on the affected part, every day 1-2 time;

Make medicated soap with soap body as carrier, using method is identical with common medicated soap, just the soap foam can not be dashed and wipe away, and treats that the nature drying covers on the skin, and soap body is a kind of surfactant, can increase infiltration, the Absorption of medicament, thereby increases the curative effect of medicament.

Claims

1, a kind of treatment dermatosis medicament, it is characterized in that it is that raw material gets with the conventional method refinement by Chinese medicine Flos Lonicerae, Cortex Phellodendri, Radix Sophorae Flavescentis, Cortex Dictamni, dried Alumen, sulfur, Realgar, raw material each component consumption by weight is: Flos Lonicerae 25-50 part, Cortex Phellodendri 10-25 part, Radix Sophorae Flavescentis 10-25 part, Cortex Dictamni 10-25 part, dried Alumen 50-80 part, sulfur 10-20 part, Realgar 10-20 part.