CN104127746A - Traditional Chinese medicinal composition for balancing and nourishing, and preparation method and application thereof - Google Patents
Traditional Chinese medicinal composition for balancing and nourishing, and preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal composition for balancing and nourishing. Effective components of the traditional Chinese medicinal composition are prepared by using the following raw materials, by weight, 1-40 parts of Dendrobium officinale, 1-40 parts of Semen Euryales, 1-40 parts of coix seed, 1-40 parts of white hyacinth bean, 1-40 parts of lotus seed, 1-40 parts of Chinese yam, 1-40 parts of jujube, 1-40 parts of longan and 1-40 parts of lily. The traditional Chinese medicinal composition for balancing and nourishing is safe and nontoxic and contains no chemical preparations. Clinic experiments prove that the traditional Chinese medicinal composition for balancing and nourishing can effectively adjust listlessness, physique weakness, insomnia, restless sleep, immunity decrease, anorexia, forgetfulness, frequent colds, easy infection of oral ulcers, and other symptoms, and the effective rate reaches above 85%.
Description
Technical field
The present invention relates to Chinese medicine composition field, particularly relate to a kind of Chinese medicine composition with balance nourishing effects and its preparation method and application.
Background technology
Theory of Chinese medical science thinks that Healthy People should be the organism of balance coordination, and " Plain Questions vital QI of the body connecting with natural QI opinion " has literary composition: " YIN and YANG in a relative equilibrium, life activities being normally maintained.Dissociation of YIN from YANG, exhaustion of vital essence." " putting down " here all refer to balance with " secret ", points out that balance is " spirit is controlled " taking negative and positive as guiding principle, able-bodied basic." Plain Questions regulating menstruation opinion " also defines normal person: " negative and positive are even flat, and to fill its shape, if nine times one, life is said normal person." normal body by self regulation, maintains the relative equilibrium of yin-Yang QI and blood, ascending, descending, exiting and entering in certain limit.
Modern society's life anxiety and operating pressure are large; and with advancing age; people often there will be feel run-down, lethargy, poor sleeping quality, immunity are poor, without appetite, easily forgetful, easily enrage, regular flu or the symptom such as oral ulcer, constipation; do medical examination and also can not check the concrete state of an illness, it is " subhealth state " that the conclusion that doctor provides tends to.Subhealth state is a kind of critical state, in the people of sub-health state, although there is no clear and definite disease, occurs the decline of spiritual vigor and adaptive capacity, if this state can not be corrected timely, is very easy to cause somatopsychic illness.
According to the survey, the patient age in sub-health state is many between 15 to 49 years old for root, and wherein city white collar, especially women occupy the majority.The people of this age bracket is because face the social activity such as college entrance examination is entered a higher school, commercial dinner party, enterprise operation, human communication, position competition; long-term in nervous ambient pressure; if scientifically oneself adjusts and self-protection, just easily enter sub-health state.
In existing market, improve sub-health state, strengthen body immunity, regulate the health product of total balance of the body more and more, but its prescription emphasizes particularly on different fields a little mostly, be difficult to comprehensive balance function of human body, and mostly add chemicals, in order to assist a ruler in governing a country treatment and to promote drug effect, after these chemicals are absorbed by the body, easily occur the various symptoms that are not suitable with, can not long-term taking, and toxic and side effects is larger.
Summary of the invention
Based on this, the object of the present invention is to provide a kind of Chinese medicine composition with balance nourishing effects.
For achieving the above object, the present invention takes following technical scheme:
A kind of balance tonic Chinese medicine compositions, the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion: 1～40 part of Herba Dendrobii, 1～40 part of Semen Euryales, 1～40 part of Semen Coicis, 1～40 part of Semen Lablab Album, 1～40 part of Semen Nelumbinis, 1～40 part of Rhizoma Dioscoreae, 1～40 part, Fructus Jujubae, 1～40 part of Arillus Longan, 1～40 part of Bulbus Lilii.
In some embodiment, the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion therein: 1～10 part of Herba Dendrobii, 1～10 part of Semen Euryales, 1～10 part of Semen Coicis, 1～10 part of Semen Lablab Album, 1～10 part of Semen Nelumbinis, 1～10 part of Rhizoma Dioscoreae, 1～10 part, Fructus Jujubae, 1～10 part of Arillus Longan, 1～10 part of Bulbus Lilii.
In some embodiment, the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion therein: 1～2 part of Herba Dendrobii, 2～4 parts of Semen Euryaless, 2～4 parts of Semen Coiciss, 2～4 parts of Semen Lablab Albums, 2～4 parts of Semen Nelumbiniss, 2～4 parts of Rhizoma Dioscoreaes, 2～4 parts, Fructus Jujubae, 2～4 parts of Arillus Longans, 2～4 parts of Bulbus Liliies.
In some embodiment, the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion therein: 1 part of Herba Dendrobii, 3 parts of Semen Euryaless, 3 parts of Semen Coiciss, 3 parts of Semen Lablab Albums, 3 parts of Semen Nelumbiniss, 3 parts of Rhizoma Dioscoreaes, 3 parts, Fructus Jujubae, 3 parts of Arillus Longans, 3 parts of Bulbus Liliies.
The preparation method of above-mentioned balance tonic Chinese medicine compositions, comprises the steps:
After the Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii, Arillus Longan, Fructus Jujubae are cured, pulverize, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form; Or,
The Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii, Arillus Longan, Fructus Jujubae are merged, and extracting in water, filters, obtain filtrate, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form; Or,
The Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii, Arillus Longan, Fructus Jujubae are merged, pulverize, extracting in water, filter, obtain filtrate, after described filtrate is concentrated, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form.
Therein in some embodiment, described in the temperature of curing be 50 DEG C～80 DEG C.
Above-mentioned balance tonic Chinese medicine compositions has the application in the medicine of balance nourishing effects in preparation.
In some embodiment, the dosage form of described medicine is therein: tablet, capsule, pill, granule, powder, oral liquid, decoction or unguentum.
Acceptable adjuvant can be according to one or more in filler, disintegrating agent, lubricant, suspending agent, binding agent, sweeting agent, correctives, antiseptic need to elected as of dosage form on medicine of the present invention or on health food, wherein,
Filler can be one or more in starch, pregelatinized Starch, lactose, mannitol, chitin, microcrystalline Cellulose, sucrose;
Disintegrating agent can be one or more in starch, pregelatinized Starch, microcrystalline Cellulose, carboxymethyl starch sodium, crospolyvinylpyrrolidone, low-substituted hydroxypropyl cellulose, cross-linking sodium carboxymethyl cellulose;
Lubricant can be one or more in magnesium stearate, sodium lauryl sulphate, Pulvis Talci, silicon dioxide;
Suspending agent can be one or more in polyvinylpyrrolidone, microcrystalline Cellulose, sucrose, agar, hydroxypropyl emthylcellulose;
Binding agent can be one or more in starch slurry, polyvinylpyrrolidone, hydroxypropyl emthylcellulose;
Sweeting agent can be one or more in saccharin sodium, Aspartane, sucrose, cyclamate, enoxolone;
Correctives can be sweeting agent or/and essence;
Antiseptic can be that parabens, benzoic acid, sodium benzoate, sorbic acid and its esters, benzalkonium bromide, acetic acid chloroethene are fixed, one or more in eucalyptus oil.
Principle and advantage of the present invention is as follows:
Conventionally, in sub-health state crowd show as that weak weak, lethargy, insomnia are peaceful, immunologic function degression, without appetite, the easy symptom such as forgetful, regular flu, oral ulcer.
Balance tonic Chinese medicine compositions of the present invention is selected the Chinese crude drugs such as Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Fructus Jujubae, Arillus Longan, Bulbus Lilii, compatibility mutually, overcome the deficiency that single medicinal material effect is single, strengthen drug effect, suppress or elimination toxic and side effects, many-sided regulation and control, to reach effect of balance nourishing.Balance tonic Chinese medicine compositions of the present invention is taking Rhizoma Dioscoreae as monarch drug, spleen invigorating lung benefiting, and supplementing the kidney to control the nocturnal, main weakness of the spleen and stomach, lack of appetite body is tired, has loose bowels, and chronic cough of deficiency lung, the nocturnal emission of suffering from a deficiency of the kidney is sliding, frequent micturition etc.; Compatibility Semen Nelumbinis, Semen Lablab Album, Semen Coicis, Semen Euryales, principal drug assistance is with invigorating the spleen and benefiting QI, and middle removing dampness, is ministerial drug.Bulbus Lilii mind tranquilizing and the heart calming, assistant Arillus Longan heart tonifying and tranquilizing, the strengthening the spleen that nourishes blood, adds the Fructus Jujubae of beneficial heart and tranquilizing mind, is combined into adjuvant drug, plays altogether the effect of nourishing blood to tranquillize the mind; Herba Dendrobii Yin-nourishing and body fluid promoting, strengthening the spleen and nourishing the stomach, both tonifying-Yin and nourishing-stomach and do not hold back heresy; Medicine that again can anti-group warm-dryness syndrome too and imapirment of the spleen and stomach.All medicines share, and complement each other, and reach QI invigorating tonify deficiency, keep fit brain-strengthening, regulate effect of subhealth state, and described raw material all adopts the raw material of the integration of edible and medicinal herbs that Ministry of Public Health announces, edible safety, and long-term taking can not cause harmful effect to human body.
Compared with prior art, the present invention has following beneficial effect:
(1) balance tonic Chinese medicine compositions of the present invention is safe, nontoxic, not containing chemicals, and by clinical trial certificate, balance tonic Chinese medicine compositions of the present invention can effectively regulate lethargy, weak weak, insomnia is peaceful, immunologic function degression, without appetite, easily forgetful, regular flu, easily suffer from the symptoms such as oral ulcer, and effective percentage reaches more than 85%.
(2) preparation method of balance tonic Chinese medicine compositions of the present invention, simple to operation.
Detailed description of the invention
Use the rare wildlife and plants production of being used as medicine because state's laws provide against, Herba Dendrobii of the present invention can be trained to breed with pseudo-wild cultivating by group and obtain.
Below in conjunction with specific embodiment, balance tonic Chinese medicine composition and method of making the same of the present invention and application are described further.
The present invention discloses a kind of balance tonic Chinese medicine compositions, and the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion: 1～40 part of Herba Dendrobii, 1～40 part of Semen Euryales, 1～40 part of Semen Coicis, 1～40 part of Semen Lablab Album, 1～40 part of Semen Nelumbinis, 1～40 part of Rhizoma Dioscoreae, 1～40 part, Fructus Jujubae, 1～40 part of Arillus Longan, 1～40 part of Bulbus Lilii.Be preferably by the raw material of following weight portion and be prepared from: 1～10 part of Herba Dendrobii, 1～10 part of Semen Euryales, 1～10 part of Semen Coicis, 1～10 part of Semen Lablab Album, 1～10 part of Semen Nelumbinis, 1～10 part of Rhizoma Dioscoreae, 1～10 part, Fructus Jujubae, 1～10 part of Arillus Longan, 1～10 part of Bulbus Lilii.Most preferably be by the raw material of following weight portion and be prepared from: 1 part of Herba Dendrobii, 3 parts of Semen Euryaless, 3 parts of Semen Coiciss, 3 parts of Semen Lablab Albums, 3 parts of Semen Nelumbiniss, 3 parts of Rhizoma Dioscoreaes, 3 parts, Fructus Jujubae, 3 parts of Arillus Longans, 3 parts of Bulbus Liliies.Balance tonic Chinese medicine compositions of the present invention is safe, nontoxic, not containing chemicals, and by clinical trial certificate, balance tonic Chinese medicine compositions of the present invention can effectively regulate lethargy, weak weak, insomnia is peaceful, immunologic function degression, without appetite, easily forgetful, regular flu, easily suffer from the symptoms such as oral ulcer, and effective percentage reaches more than 85%.
The present invention also discloses the preparation method of above-mentioned balance tonic Chinese medicine compositions, comprises the steps:
After the Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii, Arillus Longan, Fructus Jujubae are cured, pulverize, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form; Or,
The Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii, Arillus Longan, Fructus Jujubae are merged, and extracting in water, filters, obtain filtrate, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form; Or,
The Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii, Arillus Longan, Fructus Jujubae are merged, pulverize, extracting in water, filter, obtain filtrate, after described filtrate is concentrated, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form.
The temperature of curing wherein, is preferably 50 DEG C～80 DEG C.
The preparation method of this resolving depression Chinese medicine composition of calming the nerves, simple to operation.
The present invention also discloses above-mentioned balance tonic Chinese medicine compositions and has the application in the medicine of balance nourishing effects in preparation.The dosage form of described medicine can be: tablet, capsule, pill, granule, powder, oral liquid, decoction or unguentum.
It is below specific embodiment.
Embodiment 1
The Chinese medicine composition of a kind of balance nourishing effects of the present embodiment, its effective ingredient is mainly prepared from by the raw material of following weight: Herba Dendrobii 2g, Semen Euryales 6g, Semen Coicis 6g, Semen Lablab Album 6g, Semen Nelumbinis 6g, Rhizoma Dioscoreae 6g, Fructus Jujubae 6g, Arillus Longan 6g, Bulbus Lilii 6g.
The granule being made by above-mentioned balance tonic Chinese medicine compositions, its raw material by following weight is prepared from:
Major ingredient: above-mentioned Chinese medicine composition;
Adjuvant: Mel 10g, sucrose 2g.
The preparation method of above-mentioned granule, comprises the steps:
(1) Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii are cured respectively at 60～80 DEG C, after remove portion moisture, mixed powder is broken into coarse powder;
(2) Arillus Longan, Fructus Jujubae are cured respectively at 60～80 DEG C, after remove portion moisture, join successively in the described coarse powder of step (1), progressively pulverize, mix homogeneously, crosses 200 mesh sieves, obtains mixed powder;
(3) by sucrose drying and crushing at 60～80 DEG C, and cross 80 mesh sieves, join in the described mixed powder of step (2), then add Mel 10g, obtain mixed material;
(4) spraying adds the ethanol that is equivalent to described mixed material weight 5%, and granulation, dry, 20 order granulate, obtain described granule.
Embodiment 2
The Chinese medicine composition of a kind of balance nourishing effects of the present embodiment, its effective ingredient is mainly prepared from by the raw material of following weight: Herba Dendrobii 2g, Semen Euryales 5g, Semen Coicis 2g, Semen Lablab Album 5g, Semen Nelumbinis 5g, Rhizoma Dioscoreae 10g, Fructus Jujubae 5g, Arillus Longan 9g, Bulbus Lilii 5g.
The decoction being made by above-mentioned balance tonic Chinese medicine compositions, its raw material by following weight is prepared from:
Major ingredient: above-mentioned Chinese medicine composition.
The preparation method of above-mentioned decoction, comprises the steps:
(1) Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii, Arillus Longan, Fructus Jujubae merge, and add the water of 8 times of weight, soak 0.5h, and first intense fire is heated to boiling, then slow fire boiling 1h, filter, and obtain filtering residue and extracting solution;
(2) in described filtering residue, add the water of 6 times of weight, first intense fire is heated to boiling, then slow fire boiling 0.5h, filters to obtain extracting solution again;
(3) combining step (1) and (2) described extracting solution, stir, and obtains described decoction.
Embodiment 3
The Chinese medicine composition of a kind of balance nourishing effects of the present embodiment, its effective ingredient is mainly prepared from by the raw material of following weight: Herba Dendrobii 3g, Semen Euryales 10g, Semen Coicis 10g, Semen Lablab Album 10g, Semen Nelumbinis 5g, Rhizoma Dioscoreae 5g, Fructus Jujubae 10g, Arillus Longan 5g, Bulbus Lilii 10g.
The unguentum being made by above-mentioned balance tonic Chinese medicine compositions, its raw material by following weight is prepared from:
Major ingredient: above-mentioned Chinese medicine composition;
Adjuvant: Mel 12g, sucrose 3g.
The preparation method of above-mentioned unguentum, comprises the steps:
(1) Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Fructus Jujubae, Arillus Longan, Bulbus Lilii are merged, pulverize, cross 200 mesh sieves, obtain medicated powder, add the water of 8 times of weight, soak 2h, filter, obtain filtering residue and extracting solution;
(2) in described filtering residue, add again the water of 6 times of weight, soak 1.5h, filter to obtain extracting solution;
(3) combining step (1) and (2) described extracting solution, being evaporated to relative proportion is 1.45, adds Mel 12g, sucrose 3g, stirs and makes mix homogeneously, to be concentrated into relative proportion be 1.50 in 60～80 DEG C of heating again, obtains described unguentum.
Embodiment 4
The Chinese medicine composition of a kind of balance nourishing effects of the present embodiment, its effective ingredient is mainly prepared from by the raw material of following weight: Herba Dendrobii 2g, Semen Euryales 3g, Semen Coicis 3g, Semen Lablab Album 3g, Semen Nelumbinis 3g, Rhizoma Dioscoreae 3g, Fructus Jujubae 3g, Arillus Longan 3g, Bulbus Lilii 3g.
The capsule being made by above-mentioned balance tonic Chinese medicine compositions, its raw material by following weight is prepared from:
Major ingredient: above-mentioned Chinese medicine composition;
Adjuvant: Pulvis Talci 0.2g, magnesium stearate 0.2g.
The preparation method of above-mentioned capsule, comprises the steps:
(1) Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii are cured respectively at 60～80 DEG C, after remove portion moisture, mixed powder is broken into coarse powder;
(2) Arillus Longan, Fructus Jujubae are cured respectively at 60～80 DEG C, after remove portion moisture, join successively in the described coarse powder of step (1), progressively pulverize, mix homogeneously, crosses 200 mesh sieves, obtains mixed powder;
(3) in the described mixed powder of step (2), add Pulvis Talci 0.2g, magnesium stearate 0.2g, mix homogeneously, filling capsule, obtains described capsule.
Embodiment 5
The Chinese medicine composition of a kind of balance nourishing effects of the present embodiment, its effective ingredient is mainly prepared from by the raw material of following weight: Herba Dendrobii 3g, Semen Euryales 10g, Semen Coicis 10g, Semen Lablab Album 10g, Semen Nelumbinis 10g, Rhizoma Dioscoreae 9g, Fructus Jujubae 5g, Arillus Longan 5g, Bulbus Lilii 10g.
The pill being made by above-mentioned balance tonic Chinese medicine compositions, its raw material by following weight is prepared from:
Major ingredient: above-mentioned Chinese medicine composition;
Adjuvant: water 70mL and Mel 20g.
The preparation method of above-mentioned pill, comprises the steps:
(1) Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii are cured respectively at 60～80 DEG C, after remove portion moisture, mixed powder is broken into coarse powder;
(2) Arillus Longan, Fructus Jujubae are cured respectively at 60～80 DEG C, after remove portion moisture, join successively in the described coarse powder of step (1), progressively pulverize, mix homogeneously, crosses 200 mesh sieves, obtains mixed powder;
(3) at the described mixed powder of step (2), add water 70mL and Mel 20g, soft material processed, pill, dry, select ball, capping, obtains described pill.
Embodiment 6
The Chinese medicine composition of a kind of balance nourishing effects of the present embodiment, its effective ingredient is mainly prepared from by the raw material of following weight: Herba Dendrobii 1g, Semen Euryales 5g, Semen Coicis 5g, Semen Lablab Album 5g, Semen Nelumbinis 5g, Rhizoma Dioscoreae 5g, Fructus Jujubae 4g, Arillus Longan 4g, Bulbus Lilii 4g.
The oral liquid being made by above-mentioned balance tonic Chinese medicine compositions, its raw material by following weight is prepared from:
Major ingredient: above-mentioned Chinese medicine composition;
Adjuvant: sodium benzoate 7g and sucrose 3g.
The preparation method of above-mentioned oral liquid, comprises the steps:
(1) Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Fructus Jujubae, Arillus Longan, Bulbus Lilii merge, and add the water of 8 times of weight, soak 0.5h, and first intense fire is heated to boiling, then slow fire boiling 1h, filter, and obtain filtering residue and extracting solution;
(2) in described filtering residue, add the water of 6 times of weight, first intense fire is heated to boiling, then slow fire boiling 0.5h, filters to obtain extracting solution again;
(3) combining step (1) and (2) described extracting solution, stir, and removes precipitation or not tolerant, is concentrated into 350ml-400mL, adds sodium benzoate 5g and sucrose 3g to carry out dosing, obtains described oral liquid.
Embodiment 7
The Chinese medicine composition of a kind of balance nourishing effects of the present embodiment, its effective ingredient is mainly prepared from by the raw material of following weight: Herba Dendrobii 5g, Semen Euryales 20g, Semen Coicis 20g, Semen Lablab Album 20g, Semen Nelumbinis 20g, Rhizoma Dioscoreae 20g, Fructus Jujubae 19g, Arillus Longan 19g, Bulbus Lilii 19g.
The powder being made by above-mentioned balance tonic Chinese medicine compositions, its raw material by following weight is prepared from:
Major ingredient: above-mentioned Chinese medicine composition.
The preparation method of above-mentioned powder, comprises the steps:
(1) Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii are cured respectively at 60～80 DEG C, after remove portion moisture, mixed powder is broken into coarse powder;
(2) by Fructus Jujubae, Arillus Longan, cure respectively at 60～80 DEG C, after remove portion moisture, join successively in the described coarse powder of step (1), progressively to pulverize, mix homogeneously, crosses 100 mesh sieves, obtains described powder.
Embodiment 8
The Chinese medicine composition of a kind of balance nourishing effects of the present embodiment, its effective ingredient is mainly prepared from by the raw material of following weight: Herba Dendrobii 10g, Semen Euryales 40g, Semen Coicis 40g, Semen Lablab Album 40g, Semen Nelumbinis 40g, Rhizoma Dioscoreae 40g, Fructus Jujubae 39g, Arillus Longan 39g, Bulbus Lilii 39g.
The tablet being made by above-mentioned balance tonic Chinese medicine compositions, its raw material by following weight is prepared from:
Major ingredient: above-mentioned Chinese medicine composition;
Adjuvant: sucralose 10g, sorbitol 112g, silica 1 0g, microcrystalline Cellulose 25g.
The preparation method of above-mentioned tablet, comprises the steps:
(1) Herba Dendrobii, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Bulbus Lilii are carried out separately to 60～80 DEG C and cure, remove after part moisture, be ground into coarse powder;
(2) Fructus Jujubae, Arillus Longan are carried out to 60～80 DEG C and cure, join successively in the described coarse powder of step (1), mix homogeneously, progressively pulverizes, and mix homogeneously is crossed 80 mesh sieves, obtains mixed powder;
(3) by sucralose 10g, sorbitol 112g, silica 1 0g, microcrystalline Cellulose 25g, cross after 80 mesh sieves, mix homogeneously with the described mixed powder of step (2), add 75% ethanol 150mL soft material processed, granulate, dry, granulate, adds adjuvant tabletting, obtains described tablet.
Embodiment 9
It described in the present embodiment, is the safety toxicological experiment of balance tonic Chinese medicine compositions.
(1) granule described in laboratory sample and character: embodiment 1, brown granule, is modulated into each concentration by it with distilled water, for examination.
(2) laboratory animal: Wistar rat and Kunming kind white mice, provided by drug research institute of Central South University animal center receptacle.
(3) experimental technique:
3.1 acute toxicity testings: with acute toxicity half lethal dose toxicity grading, do not measure laboratory sample half lethal dose (LD
50), Kunming kind white mice is 200g/kg/ day to the maximum tolerated dose of laboratory sample, gets 20 Kunming kind white mice according to maximum tolerated dose administration, Continuous Observation 7 days, and 20 Kunming kind white mice all survive, and do not occur abnormal response.Described maximum tolerated dose is equivalent to 600 times of clinical adult dose for oral use.
3.2 tetrazolium bromides (MTT) cytotoxicity experiment: adopt mtt assay to carry out cytotoxicity analysis to laboratory sample, experiment repeats 3 times, does not measure LD
50, ED
0(maximum no-effect dose)=1g (laboratory sample)/10mL (culture fluid).
3.3 micronucleus tests: laboratory sample Micronucleus experimental result is negative.
3.4 Salmonella typhimurium back mutation experiments (Ames): laboratory sample Ames experimental result is negative.
3.5 long term toxicity tests:
The Wistar rat in 40 6 week ages, body weight (180 ± 20) g, male and female half and half, adaptability was fed after 2 days, divided 4 groups at random by Wistar rat, comprised matched group, low dose group, middle dosage group and high dose group, and 10 every group, male and female half and half; Dosage is designed to: low dose group 10g/kg, middle dosage group 20g/kg, high dose group 40g/kg, matched group give isopyknic distilled water; Administering mode is: every day 1 time, continuous 30 days.
Dosage described in low dose group, middle dosage group and high dose group, is equivalent to respectively 12.5 times, 25 times and 50 times of clinical adult dose for oral use.After 30 days, Wistar rat growing state is good, by whether safety non-toxic of the confirmatory experiment samples such as growing state and body weight, histological examination, dirty body ratio, blood routine examination, blood biochemistry checking, result adopts SPSS18.0 statistical analysis software to carry out statistical analysis, result mean+SD
represent, between group, relatively check with t.
3.5.1 growing state and body weight
Matched group Wistar rat and low dose group, middle dosage group and high dose group Wistar rat are compared to ordinary circumstance (as activity, feed, growth promoter) no significant difference.
Before administration,, after 30 days 4 groups of Wistar rat body weight are measured with administration, statistical analysis, the results are shown in Table 1.
Table 1
* relatively there are significant difference, p<0.05 with matched group; * and matched group relatively have utmost point significant difference, p<0.01.
Known by table 1, before administration and administration after 30 days, the body weight of high, medium and low dosage group Wistar rat is all without significant difference (p>0.05) compared with matched group, and laboratory sample does not make significant difference to Wistar rat body weight.
3.5.2 histological examination
After administration 30 days, put to death Wistar rat, dissect:
Perusal, compared with matched group, the organs such as the heart of all the other 3 groups of Wistar rat, liver, spleen, lung, kidney, stomach, intestinal are all normal;
Microscopic examination, compared with matched group, the organs such as the heart of all the other 3 groups of Wistar rat, liver, spleen, lung, kidney are showed no abnormality.
3.5.3 dirty body ratio
Get the heart, liver, spleen, lung, kidney, the testis (or ovary) of 4 groups of Wistar rat and weigh and compared with body weight, calculate dirty body ratio, statistical analysis, the results are shown in Table 2.
Table 2
* relatively there are significant difference, p<0.05 with matched group; * and matched group relatively have utmost point significant difference, p<0.01.
Being known by table 2, all there is not significant difference (p>0.05) in the dirty body of high, medium and low dosage group Wistar rat than compared with matched group, laboratory sample does not make significant difference to the dirty body ratio of Wistar rat.
3.5.4 blood routine examination
4 groups of Wistar rat are carried out to blood routine examination, Index for examination is: red blood cell count(RBC) (RBC), platelet count (PLT), numeration of leukocyte (WBC), hemoglobinometry (HGB), male and female zero difference, therefore check result is averaged, statistical analysis, as shown in table 3.
Table 3
* relatively there are significant difference, p<0.05 with matched group; * and matched group relatively have utmost point significant difference, p<0.01.
Known by table 3, all there is not significant difference (p>0.05) in the blood routine examination result of high, medium and low dosage group Wistar rat compared with matched group, and laboratory sample does not make significant difference to Wistar rat routine blood test.
3.5.5 blood biochemistry checking
The blood biochemistry checking of 4 groups of Wistar rat, each Index for examination is as follows:
Liver function: glutamate pyruvate transaminase (ALT), glutamic oxaloacetic transaminase, GOT (AST), total serum protein (TP) and serum albumin (ALB); Renal function: blood urea nitrogen (BUN) and creatinine (CRE); Blood glucose: blood glucose (GLU); Blood fat: cholesterol (TC) and serum triglycerides (TG).
Check result statistical analysis, as shown in table 4.
Table 4
* relatively there are significant difference, p<0.05 with matched group; * and matched group relatively have utmost point significant difference, p<0.01.
Known by table 4, all there is not significant difference (p>0.05) in the blood biochemistry checking result of high, medium and low dosage group Wistar rat, laboratory sample does not make significant difference to Wistar rat blood parameters compared with matched group.
In sum, described in the embodiment of the present invention 1, granule is safe, nontoxic.
Embodiment 10
It described in the present embodiment, is the function assessment experiment of balance tonic Chinese medicine compositions.
(1) granule described in laboratory sample and character: embodiment 1, brown granule.
(2) laboratory animal: 60 of kunming mices, SPF level, body weight 18～22g.Provided by Hunan University of Traditional Chinese Medicine's Experimental Animal Center.
(3) experimental technique:
60 kunming mices are divided into 3 groups at random: normal group, matched group, treatment group, 20 every group (wherein 10 exhaust swim test for power, and 10 are detected for index).
Model preparation: force the 8h that stands in the kunming mice water of matched group and treatment group every day, continuous 9 days, prepare fatigue type sub-health kunming mice model.
Treatment: after model preparation finishes, treatment group gives laboratory sample gavage, and dosage is 0.8g/kg, every day 3 times, continuous 7 days; Normal group, matched group give the normal saline of respective volume, continuous 7 days.
(4) experimental result:
Experimental result adopts SPSS18.0 statistical analysis software to carry out statistical analysis, result mean+SD
represent, between group, relatively check with t.
4.1 on the ethological impact of kunming mice outward appearance
Observe the variation such as color and luster of the mental status, active situation, body weight, diet, pawl, nose, lip, ear, fur and the defecation of 3 groups of kunming mices in therapeutic process.
Result: normal group kunming mice shows no obvious abnormalities; Matched group kunming mice tired mind, diet still can, body weight is slightly fallen, whole body fur has the phenomenon of soaking, and soaks area between 1/3 to 2/3, the gloomy gloss of owing of fur, leave over water stain, escape reaction reduce; By comparison, treatment group kunming mice ergasia is normal gradually, and body weight increases, and build is full, and fur recovers gloss gradually.
4.2 impacts on kunming mice fatigue strength
10 kunming mices that exhaust swim test for power described in each group are carried out to power and exhaust swim test, method of testing is: lie in the plummet of 7% own wt after the afterbody of kunming mice, the kunming mice of heavy burden is put into the bucket of 25 DEG C of water temperatures, it is the mice nose 10s that sinks under the water that power exhausts swimming standard.Measure kunming mice fatigue strength with swimming time, measurement result statistical analysis, as shown in table 5.
Table 5
▲relatively there are significant difference, p<0.05 with normal group;
▲ ▲relatively there are utmost point significant difference, p<0.01 with normal group; * relatively there are significant difference, p<0.05 with matched group; * and matched group relatively have utmost point significant difference, p<0.01.
Known by table 5, matched group is extremely significantly (P < 0.01) of difference compared with normal group, treatment group is extremely significantly (P < 0.01) of difference compared with matched group, not remarkable (P>0.05) of difference compared with normal group, explanation thus, kunming mice fatigue strength and normal group after laboratory sample treatment are suitable, and kunming mice antisecosis is normal.
4.3 affect kunming mice immune organ
10 kunming mices for index test described in each group are carried out to Thymus and Spleen index mensuration, measurement result statistical analysis, as shown in table 6.
Table 6
▲relatively there are significant difference, p<0.05 with normal group;
▲ ▲relatively there are utmost point significant difference, p<0.01 with normal group; * relatively there are significant difference, p<0.05 with matched group; * and matched group relatively have utmost point significant difference, p<0.01.
Known by table 6, the Thymus and Spleen index of matched group kunming mice is all significantly lower than normal group (P < 0.01 or P < 0.05); Treatment group is extremely significantly (P < 0.01) of difference compared with matched group, slightly high compared with normal group, but difference is remarkable (P>0.05) not, explanation thus, the kunming mice immune organ after laboratory sample treatment recovers normal.
4.3 impacts on kunming mice immunocyte
10 kunming mices for index test described in each group are carried out to the corresponding stimulation index (T lymphocyte is that ConA stimulates, and bone-marrow-derived lymphocyte is that LPS stimulates) of T, bone-marrow-derived lymphocyte and measure, measurement result statistical analysis, as shown in table 7.
Table 7
▲relatively there are significant difference, p<0.05 with normal group;
▲ ▲relatively there are utmost point significant difference, p<0.01 with normal group; * relatively there are significant difference, p<0.05 with matched group; * and matched group relatively have utmost point significant difference, p<0.01.
Known by table 7, the T lymphocyte stimulation indices of matched group kunming mice and bone-marrow-derived lymphocyte stimulation index are all significantly lower than normal group (P < 0.01 or P < 0.05); Treatment group is extremely significantly (P < 0.01) of difference compared with matched group, be significantly increased trend, and not remarkable (P>0.05) of difference compared with normal group, explanation thus, the immunocyte of the kunming mice after laboratory sample treatment recovers normal level.
To sum up know, granule contributes to strengthen muscle power and the immunity of kunming mice described in the embodiment of the present invention 1.Significantly improve its sub-health state.
Embodiment 11
It described in the present embodiment, is the clinical experiment of balance tonic Chinese medicine compositions.
(1) granule described in laboratory sample: embodiment 1.
(2) experimental subject: obvious person's 45 examples of lethargy symptom; Obvious person's 45 examples of weak weak symptom; Not peaceful obvious person's 45 examples of symptom of insomnia; Obvious person's 45 examples of immunologic function degression person symptom; Without obvious person's 45 examples of appetite symptom; Easily forgetful, easily enrage obvious person's 45 examples of symptom; Obvious person's 45 examples of regular cold symptoms; Easily suffer from obvious person's 45 examples of oral ulcer symptom.
(3) experimental technique:
3.1 Therapeutic Method: experimental subject is divided into treatment group, matched group 1 and matched group 2, the peaceful obvious person of symptom of every group of obvious person of lethargy symptom, the obvious person of weak weak symptom, insomnia, the obvious person of immunologic function degression person symptom, without the obvious person of appetite symptom, easily forgetful, easily enrage the obvious person of symptom, the obvious person of regular cold symptoms, easily suffer from each random assortment 15 examples of the obvious person of oral ulcer symptom.
Treatment group: granule described in oral embodiment 1,6g/ time, every day 3 times (rise morning after half an hour once, before lunch, dinner, half an hour is respectively once), one week is a course for the treatment of, serve on 4 courses for the treatment of; For consolidating curative effect, health invigorating, after withdrawing two weeks, then adds 2 courses for the treatment of, evaluation curative effect; Matched group 1: a kind of Chinese medicine composition composition granule, formula and the preparation method of granule is basic identical described in itself and embodiment 1, difference is: in major ingredient containing Herba Dendrobii and Bulbus Lilii; Matched group 2: a kind of Chinese medicine composition composition granule, the preparation method of granule is basic identical described in itself and embodiment 1, difference is: in major ingredient only containing Herba Dendrobii and Bulbus Lilii.
3.2 curative effect judgment standards
Symptom is improved degree: improvement degree is divided into effective, effective, invalid.
Effective: 100% original transference cure;
Effective: more than 60% original transference cure or alleviate;
Invalid: original symptom below 60% alleviates or be complete in alleviating.
(4) experimental result:
The symptom of clinical observation on the therapeutic effect experimental subject is improved situation, and result is as shown in table 8.
Table 8
As shown in Table 8, take granule described in the embodiment of the present invention 1, can effectively regulate lethargy, weak weak, have a sleepless night not peaceful, immunologic function degression, without appetite, easily forgetful, regular flu, easily suffer from the symptoms such as oral ulcer, and effective percentage reaches more than 85%, and matched group 1 and 2 effective percentage for above-mentioned symptom are between 26%～60%, as can be seen here, mutual compatibility between each raw material, make granule described in embodiment 1 can more effectively improve the lethargy of sub-health population, weak weak, have a sleepless night not peaceful, immunologic function degression, without appetite, easily forgetful, regular flu, easily suffer from the symptoms such as oral ulcer.
The above embodiment has only expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (10)
1. a balance tonic Chinese medicine compositions, it is characterized in that, the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion: 1～40 part of Herba Dendrobii, 1～40 part of Semen Euryales, 1～40 part of Semen Coicis, 1～40 part of Semen Lablab Album, 1～40 part of Semen Nelumbinis, 1～40 part of Rhizoma Dioscoreae, 1～40 part, Fructus Jujubae, 1～40 part of Arillus Longan, 1～40 part of Bulbus Lilii.
2. balance tonic Chinese medicine compositions according to claim 1, it is characterized in that, the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion: 1～10 part of Herba Dendrobii, 1～10 part of Semen Euryales, 1～10 part of Semen Coicis, 1～10 part of Semen Lablab Album, 1～10 part of Semen Nelumbinis, 1～10 part of Rhizoma Dioscoreae, 1～10 part, Fructus Jujubae, 1～10 part of Arillus Longan, 1～10 part of Bulbus Lilii.
3. balance tonic Chinese medicine compositions according to claim 2, it is characterized in that, the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion: 1～2 part of Herba Dendrobii, 2～4 parts of Semen Euryaless, 2～4 parts of Semen Coiciss, 2～4 parts of Semen Lablab Albums, 2～4 parts of Semen Nelumbiniss, 2～4 parts of Rhizoma Dioscoreaes, 2～4 parts, Fructus Jujubae, 2～4 parts of Arillus Longans, 2～4 parts of Bulbus Liliies.
4. balance tonic Chinese medicine compositions according to claim 3, it is characterized in that, the effective ingredient of described Chinese medicine composition is mainly prepared from by the raw material of following weight portion: 1 part of Herba Dendrobii, 3 parts of Semen Euryaless, 3 parts of Semen Coiciss, 3 parts of Semen Lablab Albums, 3 parts of Semen Nelumbiniss, 3 parts of Rhizoma Dioscoreaes, 3 parts, Fructus Jujubae, 3 parts of Arillus Longans, 3 parts of Bulbus Liliies.
5. the preparation method of the balance tonic Chinese medicine compositions described in claim 1-4 any one, is characterized in that, comprises the steps:
After the Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Fructus Jujubae, Arillus Longan, Bulbus Lilii are cured, pulverize, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form.
6. the preparation method of balance tonic Chinese medicine compositions according to claim 5, is characterized in that, described in the temperature of curing be 50 DEG C～80 DEG C.
7. the preparation method of the balance tonic Chinese medicine compositions described in claim 1-4 any one, is characterized in that, comprises the steps:
The Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Fructus Jujubae, Arillus Longan, Bulbus Lilii are merged, and extracting in water, filters, obtain filtrate, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form.
8. the preparation method of the balance tonic Chinese medicine compositions described in claim 1-4 any one, is characterized in that, comprises the steps:
The Herba Dendrobii of described weight portion, Semen Euryales, Semen Coicis, Semen Lablab Album, Semen Nelumbinis, Rhizoma Dioscoreae, Fructus Jujubae, Arillus Longan, Bulbus Lilii are merged and pulverized, extracting in water, filter, obtain filtrate, after described filtrate is concentrated, add acceptable adjuvant on medicine or on health food, mix and make regular dosage form.
9. the resolving depression Chinese medicine composition of calming the nerves described in claim 1-4 any one has the application in the medicine of the melancholy-relieving effect of calming the nerves in preparation.
10. application according to claim 9, is characterized in that, the dosage form of described medicine is: tablet, capsule, pill, granule, powder, oral liquid, decoction or unguentum.
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|---|---|---|---|---|
| CN108853401A (en) * | 2018-09-29 | 2018-11-23 | 河南五极中医药研究院 | Invigorating the spleen to clear away damp pathogen Chinese medicine composition of integration of drinking and medicinal herbs and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102511723A (en) * | 2012-01-09 | 2012-06-27 | 张红 | Nutritional porridge and preparation method thereof |
| JP2012207010A (en) * | 2011-03-29 | 2012-10-25 | Eri Miyata | Preparation useful for normal recovery of functional reduction in both or either in liver function and renal function test |
| CN102911831A (en) * | 2011-08-03 | 2013-02-06 | 葛双铭 | Tonic grape wine |
| CN102988828A (en) * | 2012-11-21 | 2013-03-27 | 光明食品集团云南石斛生物科技开发有限公司 | Preparation method of dendrobium officinale granula |
-
2014
- 2014-07-15 CN CN201410336088.4A patent/CN104127746A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012207010A (en) * | 2011-03-29 | 2012-10-25 | Eri Miyata | Preparation useful for normal recovery of functional reduction in both or either in liver function and renal function test |
| CN102911831A (en) * | 2011-08-03 | 2013-02-06 | 葛双铭 | Tonic grape wine |
| CN102511723A (en) * | 2012-01-09 | 2012-06-27 | 张红 | Nutritional porridge and preparation method thereof |
| CN102988828A (en) * | 2012-11-21 | 2013-03-27 | 光明食品集团云南石斛生物科技开发有限公司 | Preparation method of dendrobium officinale granula |
Non-Patent Citations (1)
| Title |
|---|
| 王惟恒: "食粥可延年", 《东方药膳》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108853401A (en) * | 2018-09-29 | 2018-11-23 | 河南五极中医药研究院 | Invigorating the spleen to clear away damp pathogen Chinese medicine composition of integration of drinking and medicinal herbs and preparation method thereof |
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