CN104122385A - Detection device and using method thereof - Google Patents

Abstract

The invention relates to a detection device which comprises a detection chamber containing a detection element for analyzing whether a sample contains substances to be analyzed. The detection device further comprises an indication element which displays whether detection is activated. The invention further relates to a using method of the detection device. The using method comprises the following steps: collecting a liquid sample, observing the indication element and judging whether the detection is activated, and detecting. The detection device and the using method have the beneficial effects that the position change of a transfer chamber can be effectively protected, moreover the operation is very simple in detection activation, and in addition, a signal can be displayed after the detection is activated, and thus detection timing and judgment are facilitated.

Description

A kind of pick-up unit and using method thereof

The application is Chinese invention patent, application number: 200910102113.1, and the applying date: point divisional application of 2009.8.13 day.

Technical field

The present invention relates to a kind of pick-up unit, especially a kind of pick-up unit that detects illegal drug.

Background technology

At present, it is more and more easier that general public obtains violated medicine, and therefore the use of violated medicine is also more and more.In order to ensure the safety of working environment and the fair competition of physical culture, employee need to detect in enterprise, unit and sports organization, athletic body fluid is for example urinated, and whether has used violated medicine to understand employee and sportsman.What therefore Humoral sample Detection and Collect device was used is more and more, and need to be operated by layman in common occasion.Use traditional liquid sample collection pick-up unit, exist the amount of liquid can not accurate quantitative analysis and produce the influential situation of testing result, the requirement can not meet the accurate quantification of liquid sample or micromanipulation time.

US Patent No. 6372515 discloses a sample collection pick-up unit, and this device comprises that is collected a urine sample cup for urine sample, and with the test card of many detector bars, detector bar is used for detecting urine sample.When use, test card is inserted to urine sample cup, allow detector bar contact with urine sample, detection can complete within a few minutes like this.After detection completes, the urine sample in urine sample cup is detected the material contamination in reagent strip, can not complete the secondary-confirmation checking that professional carries out.

ZL200420107950.6 discloses a body fluid sample pick-up unit, and by a piston hole for the end opening that glass body bottom has is set, and the through hole communicating with cup chamber and the through hole that communicates with slot carry out the transfer of liquid sample, realizes quantitatively and detecting.In disclosed utility model, comprise the first through hole and the second through hole at this section, be detained bubble and sample but which easily causes the ring groove in piston hole in reagent operating process, cause the error quantitatively detecting to cause that result is inaccurate.

ZL200720303101.1 discloses a kind of liquid sample collection pick-up unit, this pick-up unit comprises collecting chamber, test chamber and transfer chamber, transfer chamber is connected with test chamber with collecting chamber respectively by least two through holes, and wherein the opening two ends of at least one through hole are positioned at the extreme higher position of transfer chamber or the both sides of extreme lower position.This patent by change the lead to the hole site of liquid sample detection device inside solve in common pick-up unit, exist because thereby the excessive bubble producing of flow rate of liquid causes liquid sample mobile block up and for detection of the inadequate problem of the amount of sample.

Summary of the invention

The present invention relates to a kind of pick-up unit, comprise and hold the test chamber that whether contains the detecting element of analyte in analyzing samples, and an indicator elment that shows whether detection is activated.This indicator elment, on the one hand, mainly shows whether detecting element was used, and when in the situation that has liquid sample to exist, indicator elment instruction detecting element has been used, and illustrates to detect to be activated.In addition, if before detecting, the signal being activated with regard to obtaining detection that indicator elment sends, illustrates that pick-up unit was misused, and such pick-up unit and detecting element are considered as being used, be also considered as detecting being activated simultaneously, can not for detection of.Preferably, pick-up unit also comprises and also comprises the transfer chamber of liquid sample being transferred to test chamber.More preferred, pick-up unit also comprises the collecting chamber for collecting liquid sample, and transfer chamber connects collecting chamber and test chamber.For this pick-up unit with transfer chamber, especially rely on transfer chamber liquid sample transferred to from collecting chamber the pick-up unit of test chamber, need to realize by the change of transfer chamber position the transfer of liquid sample.In a specific embodiment, the position of transfer chamber changes realizes by a push mechanism, wherein, if the liquid sample in transfer chamber has been transferred in test chamber, we can show and detect the indicator elment acquired information being activated by one, now, liquid sample, with the detection reagent strip contact in test chamber, activates and start detection reaction.Preferably, this indicator elment is followed the movement of transfer chamber and is moved, and this mode, can move the position that must react transfer chamber more directly perceived, thereby whether the more clearly detection that shows is activated.More preferred, pick-up unit also comprises a watch window, for observing indicator elment, obtains and detects the signal whether being activated.In addition, the invention still further relates to a push mechanism, this push mechanism can activate the liquid flow of transfer chamber to test chamber, and this push mechanism also comprises a barrier element linking together with push mechanism before detection is activated.This barrier element; can stop the abnormal promotion of push mechanism before detection is activated; such as in production assembling process; in transportation; collect in sample processes and other processes detected person, if there is no temporary transient " protection " effect of barrier element, cause in abnormal promotion; to make whole pick-up unit in cannot duty, this detects for quick diagnosis be disadvantageous.Preferred in addition, this barrier element being connected as a single entity with push mechanism before detection is activated, can, activating before detection, peel off from push mechanism.

The invention still further relates to the using method of pick-up unit 100: collect liquid sample; Observe indicator elment 8 and judge to detect and whether be activated; Detect.Preferably, pick-up unit 100 also comprises the transfer chamber 22 of liquid sample being transferred to test chamber 32, and indicator elment 8 is positioned at transfer chamber 22 and changes position along with the position change of transfer chamber 22.Its using method comprises: collect liquid sample; Promote transfer chamber 22 and make liquid sample flow to test chamber 32 from transfer chamber 22, wherein indicator elment 8 moves along with the movement of transfer chamber 22; Observe indicator elment 8 judgement activation detection; Detect.

Beneficial effect of the present invention

Can effectively must protect the position of transfer chamber to change, and be very easy to operation detecting while activating, in addition, can display after detection is activated, be convenient to detect timing and judgement.

Brief description of the drawings

Fig. 1 is the stereographic map of the present invention's one specific embodiment;

Fig. 2 is the front schematic view of the present invention's one specific embodiment;

Fig. 3 is the explosive decomposition figure of the present invention's one specific embodiment;

Fig. 4 is the view of the present invention's one specific embodiment before detection;

Fig. 5 is the view of the present invention's one specific embodiment in the time detecting and after detecting.

Description of reference numerals: pick-up unit (urine cup) 100; Bowl cover 1; Cup body 2, rim of a cup 20, rim of a cup screw thread 201, collecting chamber 21, piston hole (transfer chamber) 22, piston 23, rubber band 24, piston hole opening 25, open ring groove 26, upper through hole 27, lower through-hole 28, piston hole 29; Cup 3, thieving paper 31, test chamber 32, support bar 33, slot 34; O-ring seal 4; Test card (test card) 5, testing result viewing area 51, detects the reagent rule 52, plate 53, plate opening 54, adhesive sticker window 55, plate projection 56; Push mechanism 6, pushes away handle 60, and catch ring 61,63 is affectedly bashful place 62; Closed ring groove 7; Indicator elment 8.

Embodiment

Structure to pick-up unit or these technical terms using are described further below.

Detect and represent chemical examination or test a kind of material or whether material exists, such as, but be not limited to this, metabolin, nucleic acid, protein or the polymkeric substance of chemical substance, organic compound, mineral compound, metabolism product, medicine or drug metabolite, organic organization or organic organization.In addition, detect the quantity that represents test substances or material.Furtherly, chemical examination also represents immune detection, chemical detection, enzyme detection etc.

The sample of indication of the present invention refers to that those can be used for detecting, chemically examine or diagnose the material that whether has interested analyte.Sample can be, for example, liquid sample, liquid sample can comprise blood, blood plasma, serum, urine, saliva and various juice, can also comprise the liquid solution that solid sample and semi-solid samples form after anticipating.Collect the sample coming and can detect whether there is analyte for methods such as immune detection, chemical detection, enzyme detections.

Can analyze any analyte by apparatus and method of the present invention.Can comprise with the example of the analyte of apparatus and method stable detection of the present invention (but not only comprising) human chorionic gonadotrophin (hCG), lutropin (LH), ovarian stimulation element (FSH), hepatitis C virus (HCV), hepatitis B (HBV), hepatitis B surface antigen, the medicine of AIDS virus and any abuse.Analyte can detect in any liquid or liquefied sample, for example urine, saliva, saliva, blood, blood plasma, or serum.The example of other analyte also has the acid of flesh ammonia acid anhydride, cholerythrin, nitrite, protein (nonspecific), blood, leucocyte, blood sugar, heavy metal and toxin, bacterium composition is (for example, the special protein and sugar of the bacterium of particular type divides, and any other analyte of applicable lateral flow assay form can detect with this device.

Analyte can also be some haptens materials, and these haptens comprise drugs (as drug abuse)." drug abuse " (DOA) refers to that non-medical destination is used medicine (conventionally playing paralysis neural).Abuse these medicines and can cause body & mind to suffer damage, produce dependence, addicted and/or dead.The example of drug abuse comprises cocaine; Amphetamine (for example, black beauty, white amphetamine tablet, dextroamphetamine, dexie, Beans); Crystal methamphetamine (crank, meth, crystal, speed); Barbiturate (as Valium, Roche Pharmaceuticals, Nutley, New Jersey); Sedative (paramedicines of sleeping); Lysergic acid diethylamide (LSD); Inhibitor (downers, goofballs, barbs, blue devils, yellow jackets, methaqualone); The anti-antidepressant of tricyclic antidepressants (TCA, i.e. imipramine, amitriptyline and doxepin); Hog (PCP); Tetrahydrocannabinol (THC, pot, dope, hash, weed, etc.), opiate (being morphine, opium, codeine, heroin, hydroxyl dihydrocodeinone), anxiolytic and hypnotic sedative agent, anxiolytic is that a class is mainly used in anxiety reduction, nervous, frightened, set the mind at rest, have the medicine of hypnosis sedation concurrently, comprise Benzodiazepines (benzodiazepines, BZ), atypia BZ class, merge phenodiazine NB23C class, the tall and erect class of benzene nitrogen, the part class of BZ acceptor, open loop BZ class, diphenylmethane derivatives, piperazine carboxylic acid salt, piperidine carboxylic acid salt, Kui azoles quinoline ketone, thiazine and thiazole, other heterocyclic, imidazole type calmness/anodyne, propanediol derivative-carbamates, fatty compound, anthracene derivative etc.Use this device also can be for detection of belonging to medical usage but the easily detection of overdose, as tricyclic antidepressant (imipramine or analog) and Paracetamol etc.After these medicines are absorbed by the body, can resolve into different small-molecule substances, these small-molecule substances are present in the body fluid such as blood, urine, saliva, sweat or part body fluid exists above-mentioned small-molecule substance.

Pick-up unit

The pick-up unit 100 the present invention relates to, comprises the test chamber 32 of holding the detecting element 5 that whether contains analyte in analyzing samples.Pick-up unit 100 can be made up of multiple difformity and different materials, the plastics of for example all size.

In a concrete embodiment, pick-up unit 100 also comprises an indicator elment 8 that shows whether detection is activated.This indicator elment 8, on the one hand, mainly shows whether detecting element 5 was used, and when in the situation that has liquid sample to exist, indicator elment 8 indicates detecting element 5 to be used, and illustrates to detect to be activated.In addition on the one hand, if before detecting, the signal being activated with regard to obtaining detection that indicator elment 8 sends, illustrate that pick-up unit 100 was misused, such pick-up unit 100 and detecting element 5 are considered as being used, be also considered as detecting being activated simultaneously, can not for detection of.So detecting element 5 had been used or pick-up unit 100 was used, be all can be considered to detect be activated.The signal that detection is activated, can be indicator elment 8 itself, can be also indicator elment 8 and other materials signal forming that reacts.This indicator elment 8, comprises chemistry instruction, such as by the mode of Show Color.In one embodiment, can, by the reaction of chemical substance, such as utilizing the reaction of potassium rhodanide and ferric ion, there is wine-colored color reaction.Indicator elment also can comprise employing food coloring in a further embodiment.In another embodiment, described indicator elment 8 comprises PH agent.On indicating area, be written into the material with PH agent, such as PH test paper, according to the pH value difference of liquid sample, the pH value of urine, between 5-7, is positioned at after the PH test paper contact sample on indicating area, is infiltrated into grass green by original yellow, there is change color, reach indicative function.In addition, instruction also comprises physics instruction, in one embodiment, described indicator elment 8, it can be a coloured material, this material is covered by a basic opaque layer at least partly, in the time having liquid to exist, knows that the coloured material described in making can be observed thereby described opaque layer becomes transparent.In another embodiment, indicator elment 8 can be a colored adhesive sticker 8, and this adhesive sticker 8 is not easy in sight or hiding before detection, can more clearlyly obtain in sight after detection is activated.Preferably, pick-up unit 100 also comprises the collecting chamber 21 for collecting liquid sample, and liquid sample is transferred to the transfer chamber 22 of test chamber 32 from collecting chamber 21.Indicator elment 8 can be positioned at arbitrary position of pick-up unit, as collecting chamber 21, transfer chamber 22 or test chamber 32.Wherein more preferred, because transfer chamber 22 is to detect the key being activated, so indicator elment 8 can be positioned in transfer chamber 22.In a specific embodiment, indicator elment 8 can be positioned in transfer chamber 22, and along with the position of transfer chamber 22 changes and change position.Specifically, after collecting liquid sample, liquid sample is present in collecting chamber 21 and transfer chamber 22, now, promote transfer chamber 22 and make liquid sample enter test chamber 32, in test chamber 32, exist detecting element 5, the sample absorption piece of detecting element 5 can detect with the liquid sample of test chamber 32, detects thereby cause.Such indicator elment 8 is set, if liquid sample has entered test chamber 32, also can judge rapidly that the detection in test chamber 32 starts, therefore simultaneously, whether indicator elment 8, when whether indicating liquid sample flows to test chamber 32 from transfer chamber 22, has also indicated to detect to be activated.Preferably, transfer chamber 22 comprises the piston hole with piston 23, and piston 23 and piston hole have formed some ring grooves.Wherein liquid sample can keep in and shift in the open ring groove 26 of transfer chamber 22, and indicator elment is arranged in closed ring groove 7.In the time that the open ring groove 26 of transfer chamber 22 is pushed parts 6 and promotes to piston 23 depths, closed ring groove 7 also moves to the blind end of piston 23, and in the time that open ring groove 26 and test chamber 32 are communicated with, indicator elment 8 sends and detects the signal being activated.

More preferred, pick-up unit 100 also comprises watch window 54, is the window for observing indicator elment display.This watch window 5421, can be positioned on the collecting chamber of pick-up unit, also can be positioned at transfer chamber 22 or test chamber 32 or other positions.Being positioned at the watch window 54 on pick-up unit, can be transparent, can know to such an extent that see the signal detecting while being activated.As transparent test chamber or transfer chamber itself just can be used as watch window.Preferably, watch window 54 can be a through hole on the test board 5 of test chamber.In general, pick-up unit 100 is plastic products, and test board 5 can be designed to white plate 53 shapes, and a through hole 54 is set on plate 53, then can see that by this through hole 54 indicator elment 8 that is arranged in transfer chamber sends the signal that detects beginning.More preferred, before detection is not activated, indicator elment 8 is in primary importance, when push mechanism 6 promotes transfer chamber 22, the liquid sample in transfer chamber 22 is flow to after test chamber 32, after having promoted, indicator elment 8 is positioned at the second place, this second place faces detection window 54, the namely through hole 54 on check-out console, and the operator of pick-up unit can be perfectly clear to such an extent that see that indicator elment 8 is own and obtain the signal that detection is activated by watch window 55 so.

In another embodiment, pick-up unit 100 can comprise a push mechanism 6.Be positioned at the detecting element 5 of test chamber 32, can not spontaneously carry out, need under an action, just can be activated, push mechanism 6 can play the effect that the detection of test chamber 32 is activated.By promotion or other actions of push mechanism 6, make liquid sample enter test chamber 32, in excitation-detection liquid sample, whether contain the reaction of the detecting element 5 of analyte.Pick-up unit 100 can also comprise the collecting chamber 21 of collecting liquid sample, and connects the transfer chamber 22 of collecting chamber 21 and test chamber 32.The effect of push mechanism 6 is to make liquid sample flow to test chamber from transfer chamber, and activates detection reaction.The position of push mechanism 6, preferred, and being used in conjunction with of transfer chamber 22.In a specific embodiment, push mechanism 6 can be positioned on bowl cover 1, when needs promote, push mechanism 6 is taken out from bowl cover 1, and one end of transfer chamber 22 is pushed to other one end, realizes the transfer of liquid sample in transfer chamber 22.Preferably, push mechanism 6 is connected with transfer chamber 22, directly promotes in use this parts 6, handled easily.More preferred, this push mechanism 6 also comprises a barrier element 61,62,63.This barrier element 61,62,63rd, for preventing the abnormal promotion of push mechanism 6.Specifically, this barrier element 61,62,63, in not needing liquid to shift, stops the effect of push mechanism 6; In the time that needs liquid shifts, barrier element 61,62,63 can be disengaged, thus push mechanism 6 starts to work.In a preferred embodiment, barrier element 61,62,63 and push mechanism 6 can be connected as a single entity.So-called being connected as a single entity, definite says, before detection is activated, barrier element 61,62,63 and push mechanism 6 link together, in the time that needs activate detection, barrier element 61,62,63 can peel off from push mechanism 6, and then push mechanism 6 just can be brought into play the effect that promotes transfer chamber 22.At one, more in preferred embodiment, transfer chamber 22 is piston hole, comprises piston 23 in piston hole 22, barrier element 61,62, and 63 are wrapped in outside piston 23, and push mechanism 6 coordinates with one end of piston 23.By barrier element 61,62,63 removals from piston 23, now, push mechanism 6 can promote forward and not be subject to barrier element 61,62,63 restriction, the process of promotion can make liquid flow to test chamber 32 from transfer chamber 22, detects thereby activate.More preferred, barrier element 61,62,63 also comprise the projection that can be affectedly bashful 62, utilize this to be affectedly bashful place 62, can very conveniently barrier element 61,63 must be peeled off from push mechanism 6.

Preferred above, pick-up unit 100 can also comprise the collecting chamber 21 for collecting liquid sample, the test chamber 32 that contains test card 5 and liquid sample is transferred to the transfer chamber 22 of test chamber 32 from collecting chamber 21.

The cavity of collecting chamber 21 can adopt any shape, such as cylindrical, and syringe-like shape, chimney, or other can be used for storing any form of liquid.Collecting chamber 21 can be by cup body 2, and rim of a cup 20 and bowl cover 1 form.Rim of a cup 20 and bowl cover 1 can ensure that liquid holds and do not leak out in cup body 2 by sealing.The seal form of rim of a cup 20 and bowl cover 1 can have multiple, such as rim of a cup 20 and bowl cover 1 can have the screw thread 20 of working in coordination, reaches the effect of sealing by the mode of rotation.Better, can also in bowl cover 1, be provided with O-ring seal 4, the effect on the cup edge by O-ring seal 4 and rim of a cup 20 is played sealing function to device.

Test chamber 32 can comprise cup 3 and test card 5.The effect of cup 3 is to support whole pick-up unit in equilibrium state.The bottom of cup 3 can also include absorbent material 31 and slot, and thieving paper 31 can absorb liquid unnecessary in slot 34, and liquid can not spilt and contaminated environment from cup 3.Slot 34 is interior can be inserted with detecting element 5, for detection of whether containing analyte in liquid sample.In slot 34, also has support bar 33, for supporting the plate projection 56 on test card 5, make to be slightly suspended on the test card 5 of tape test bar the slot 34 of cup, such benefit is, in the process of detection reagent strip 52 absorption liquid sample bodies, detect reagent strip 52 state of can being always kept upright, can be because of not bending and cause affecting the object of testing result.Detecting element 5 can be selected the test strip 52 of cross flow, can be also the plate 53 with some detection reagent strips.Various detecting elements 5 can be combined and apply to together in the present invention.A kind of form is Test paper, and another kind of form can be some reagent, as being fixed on detection zone with the molecule of analyte specific binding.These reagent react and analyte are combined in to this district with analyte in sample (if existence), or are combined with the some reagent of actual zone, for the mark substance that shows detection signal and reagent area or the mark zone that separates.These detect reagent strip or detect reagent is all the familiar conventionally test means of those skilled in the art.

Transfer chamber 22 is between collecting chamber 21 and test chamber 32 and liquid can be transferred to the parts in another chamber from a chamber.Between transfer chamber 22 and collecting chamber 21 or test chamber 32, can have a common boundary, have common wall.Transfer chamber 22 can be an in check opening, and when opening opening, liquid just can flow to another one chamber along opening.Transfer chamber 22 can be also a two-way valve, and twisting valve can make two liquid between chamber circulate.Transfer chamber 22 can also be a piston hole, shift in position by piston 23 moves on to the liquid rotating in collecting chamber 21 in test chamber 32, the advantage of this transfer chamber 22 is liquid sample uniflux, can not cause in test chamber 32 through detection and the liquid of detected reagent contamination enters collecting chamber 21, be equivalent to, liquid in collecting chamber 21 is not contaminated, can be for second test or qualification.In transfer chamber 22, can comprise some through holes, wherein have upper through hole 27 to be connected with collecting chamber 21, lower through-hole 28 is connected with test chamber 32.Better, in the time that upper through hole 27 is connected with collecting chamber 21, transfer chamber 22 and collecting chamber 21 are in liquid communication state, and transfer chamber 22 and test chamber 32 are in not circulation status of liquid.Equally, in the time that transfer chamber 22 communicates with test chamber 32 by lower through-hole 28, transfer chamber 22 and collecting chamber 21 can not circulation status in liquid.Be designed with like this and be beneficial to the liquid transfer realizing between collecting chamber 21 and test chamber 32, can not make again liquid flow freely between collecting chamber 21 and test chamber 32.Transfer chamber 22 can built-in piston 23, and piston 23 and piston hole 22 are slipper seal and coordinate.The front end of piston 23 can also have dead slot, and this dead slot can be connected with collecting chamber 21 by upper through hole 27, can also be connected with test chamber 32 by lower through-hole 28.Upper through hole 27 and lower through-hole 28 can not be simultaneously and dead slot be connected.The shape of dead slot can be annular, square, can be also other rule or irregular shapes.Piston 23 can, via operator's finger or other utensils, as push mechanism changes the position of piston 23 in piston hole 22, reach the object that liquid is shifted.In transfer chamber 22, can form several ring grooves by piston 23 and piston hole 22 and rubber band 24, as the open ring groove 26 and the closed ring groove 7 that shift for liquid.To open ring groove 26 as example, in the time of initial conditions, open ring groove 26 communicates by upper through hole 27 and collecting chamber 21, and in the time there is liquid sample in collecting chamber 21, liquid can enter open ring groove 26 by upper through hole 27.Promote piston 23 make open ring groove 26 with upper through hole 27 in the state that is not connected, and when communicating with lower through-hole 28, liquid sample in open ring groove 26 can flow into test chamber 32 by lower through-hole 28, thereby whether start detection reaction, to existing analyte to detect in liquid sample.The present invention can also carry out quantitatively transfer liquid by the size of open ring groove 26.

The invention still further relates to the using method of pick-up unit 100: collect liquid sample; Observe indicator elment 8 and judge to detect and whether be activated; Detect.Preferably, pick-up unit 100 also comprises the transfer chamber 22 of liquid sample being transferred to test chamber 32, and indicator elment 8 is positioned at transfer chamber 22 and changes position along with the position change of transfer chamber 22.Its using method comprises: collect liquid sample; Promote transfer chamber 22 and make liquid sample flow to test chamber 32 from transfer chamber 22, wherein indicator elment 8 moves along with the movement of transfer chamber 22; Observe indicator elment 8 and judge to detect and whether be activated; Detect.Wherein preferred, pick-up unit 100 also comprises that an observation detects the watch window 54 whether being activated.More preferred, the using method of pick-up unit 100 comprises: collect liquid sample; Promote transfer chamber 22 and make liquid sample flow to test chamber 32 from transfer chamber 22, wherein indicator elment 8 moves along with the movement of transfer chamber 22; Position the judgement of observing indicator elment 8 from watch window 54 activate detection; Detect.

Below in conjunction with concrete accompanying drawing, embodiments of the invention is described in detail.These specific embodiment are only limited the enumerating under spirit of the present invention, do not get rid of one of ordinary skill in the art prior art and the present invention in conjunction with and other specific embodiments of producing.

Embodiment 1

As Fig. 1, shown in Fig. 2 and Fig. 3, this pick-up unit 100, comprises collecting chamber 21 and test chamber 32, and liquid rotating in collecting chamber 21 can be moved on to the piston hole (transfer chamber) 22 of test chamber 32.Collecting chamber 21 comprises glass body 2, and cup body 2 tops are provided with rim of a cup 20, and inside has a glass chamber; Rim of a cup 20 is provided with bowl cover 1, and the xsect of this bowl cover 1, rim of a cup 20 is circle, and bowl cover 1 is connected with rim of a cup 20 screw threads 201.Test chamber 32 bottoms are provided with cup 3, on cup 3, have slot 34, in slot 34, there are two support bars 33, for supporting the projection 56 on plate, make to be slightly suspended on the test card 5 of tape test bar the slot 34 of cup, such benefit is, in the process of detector bar absorption liquid sample body, detect reagent strip 52 state of can being always kept upright, can be because of not bending and cause affecting the object of testing result.Piston hole 22 communicates with cup body by the upper through hole 27 of its upper wall, and communicates with slot 34 by the lower through-hole 28 of lower wall, and cup 3 just has a translot communicating with slot 34 to lower through-hole 28 places, and lower through-hole 28 communicates with slot 34 by this translot.The built-in piston 23 of piston hole 22, this piston 23 coordinates in slipper seal with piston hole, and these piston 23 front ends have open ring groove 26.Piston 23 is at primary importance place, and open ring groove 26 communicates with cup chamber by upper through hole 27, but isolates with test board 5, becomes the cavity that can hold the liquid sample staying in glass chamber, and on piston 23, cover has rubber band 24.At second place place, open ring groove 26 is isolated but communicates with slot 34 by lower through-hole 28 with cup chamber, and upper through hole 27 and lower through-hole 28 can not communicate with open ring groove 26 simultaneously.Upper through hole 27 is positioned at the extreme higher position 7 of piston hole, and opening one end is positioned at an intersection for piston hole 22 and cup body 2 inwalls, and the other end drops on the position that transfer chamber 22 is projected on glass body 2 inwalls.Lower through-hole 28 is positioned at the extreme lower position 8 of piston hole 22, and opening one end is positioned at the intersection of piston hole 22 and cup body 2 inwalls, and the other end drops on the position of piston hole 22 projections and test chamber 32 inwalls.Upper through hole 27 and lower through-hole 28 are banded circular arc, and opening two ends are 100 degree with the angle that the longitudinal axis by piston hole 22 forms.Upper through hole 27 and lower through-hole 28 be not in same plane.In one end of piston 23, be provided with a push mechanism 6, comprise and push away handle 60 and stop ring 61,63, wherein stopping ring has two, in the middle of two obstruction rings, has one to be affectedly bashful place 62.Stop between ring 61,63 and stop ring 63 and the connection ratio that pushes away between handle 60 is easier to be peeled off, the mode of peeling off is by being affectedly bashful place 62, obstructions is encircled to 63 and tear from pushing away handle 60.In addition, on the closed ring groove 7 forming at piston 23 and piston hole 22 and rubber band 24, wrapped up the adhesive sticker 8 of one deck green.On plate 53, have in addition an aperture 54, corresponding, on the outmost pressure sensitive membrane 51 of urine cup 100, also leave a window 55 for correspondence with it.Before detecting not generation, in window 55 and aperture 54, be to can't see green adhesive sticker 7, after detection is activated, piston 23 is pushed away handle 60 and has been shifted onto relevant position, and transfer has also occurred liquid sample, same, also there is movement along with the movement of piston 23 in green adhesive sticker 8, thereby face the adhesive sticker 8 of visible green at above-mentioned aperture 54 and window 55, express liquid sample enters test chamber 32 from transfer chamber 22, detects and is activated.

As shown in Figure 4 and Figure 5, piston 23 is in the time of primary importance, and open ring groove 26 is aimed at upper through hole 27.When use, bowl cover 1 is taken off, for example urine sample of liquid sample is added to a glass chamber, liquid sample flows to from upper through hole 27 cavity that open ring groove 26 forms.Recycling is affectedly bashful place 62 and will be stopped encircling and 61,63 tear from piston 23, then pushes away handle 60 piston 23 is pushed to piston hole 22 depths, makes opening ring groove 26 aim at lower through-hole 28.Now, liquid sample flows into the translot of cup 3 from lower through-hole 28, flowing into slot 34 from translot, contacts with the test-strips 52 being inserted on slot 34, activates and detects.In the time that open ring groove 26 is aimed at lower through-hole 28, closed ring groove 7 respective aligned the aperture 54 on plate 53, in the window 55 of panel and the aperture 54 of test board of urine cup, can clearly must see green adhesive sticker signal, show to detect and activate, testing result is shown.While needing further to detect, the liquid sample in cup chamber can be delivered to laboratory and further be detected by professional, confirm testing result.

Claims (12)

1. a pick-up unit, comprises and holds the test chamber that whether contains the detecting element of analyte in analyzing samples, it is characterized in that, described pick-up unit also comprises an indicator elment that shows whether detection is activated.

2. pick-up unit as claimed in claim 1, is characterized in that, described pick-up unit also comprises the transfer chamber of liquid sample being transferred to test chamber, and described indicator elment is positioned at transfer chamber and changes position along with the position change of transfer chamber.

3. pick-up unit as claimed in claim 2, is characterized in that, described transfer chamber comprises the piston hole with piston, the open ring groove that described piston and piston hole composition shift for liquid and the closed ring groove of settling indicator elment.

4. pick-up unit as claimed in claim 1, is characterized in that, described pick-up unit also comprises that an observation detects the watch window whether being activated.

5. pick-up unit as claimed in claim 4, is characterized in that, described indicator elment can not be observed at watch window before detection is activated, and after detection is activated, can be observed at watch window.

6. the pick-up unit as described in one of claim 1 to 5, is characterized in that, described indicator elment comprises colored adhesive sticker.

7. the pick-up unit as described in one of claim 1 to 5, is characterized in that, described test chamber comprises test board, and described test board comprises a through hole, can see indicator elment by this through hole after detection is activated.

8. pick-up unit as claimed in claim 2, is characterized in that, described pick-up unit also comprises a push mechanism that makes liquid sample flow to test chamber from transfer chamber; Whether described indicator elment moves to indicate detection to be activated by the position of instruction transfer chamber.

9. pick-up unit as claimed in claim 8, is characterized in that, described push mechanism also comprises the barrier element being connected as a single entity with push mechanism.

10. pick-up unit as claimed in claim 8, it is characterized in that, described transfer chamber is the piston hole comprising with piston, described barrier element covers the outside of piston, described push mechanism is positioned at one end of piston hole, in the time that detection is not activated, barrier element and push mechanism are connected as a single entity; In the time that detection is activated, barrier element separates with push mechanism.

11. pick-up units as claimed in claim 10, is characterized in that, push mechanism activates as irreversible activation for the liquid flow of pick-up unit.

12. pick-up units as claimed in claim 1, is characterized in that, the support component that described test chamber is also erected detecting element.