CN104095242B - 一种复合锌硒多肽化合物及其制备方法 - Google Patents
一种复合锌硒多肽化合物及其制备方法 Download PDFInfo
- Publication number
- CN104095242B CN104095242B CN201410336871.0A CN201410336871A CN104095242B CN 104095242 B CN104095242 B CN 104095242B CN 201410336871 A CN201410336871 A CN 201410336871A CN 104095242 B CN104095242 B CN 104095242B
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- zinc
- water
- selenium
- polypeptide
- polypeptide compound
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- 229920001184 polypeptide Polymers 0.000 title claims abstract description 90
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 57
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 53
- 150000001875 compounds Chemical class 0.000 title claims abstract description 32
- SBIBMFFZSBJNJF-UHFFFAOYSA-N selenium;zinc Chemical compound [Se]=[Zn] SBIBMFFZSBJNJF-UHFFFAOYSA-N 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 239000002131 composite material Substances 0.000 title claims abstract description 18
- 238000006243 chemical reaction Methods 0.000 claims abstract description 25
- 239000011669 selenium Substances 0.000 claims abstract description 21
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 21
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 20
- 239000011701 zinc Substances 0.000 claims abstract description 16
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 15
- 108091005804 Peptidases Proteins 0.000 claims abstract description 5
- 102000035195 Peptidases Human genes 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 64
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 38
- 238000003756 stirring Methods 0.000 claims description 38
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 28
- 239000002994 raw material Substances 0.000 claims description 28
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical group [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims description 24
- 239000011781 sodium selenite Substances 0.000 claims description 24
- 229960001471 sodium selenite Drugs 0.000 claims description 24
- 235000015921 sodium selenite Nutrition 0.000 claims description 24
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 22
- 239000007788 liquid Substances 0.000 claims description 22
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 21
- 229940091258 selenium supplement Drugs 0.000 claims description 20
- 239000011787 zinc oxide Substances 0.000 claims description 19
- 235000014692 zinc oxide Nutrition 0.000 claims description 19
- 241000251468 Actinopterygii Species 0.000 claims description 16
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 claims description 15
- 239000004246 zinc acetate Substances 0.000 claims description 15
- 235000013904 zinc acetate Nutrition 0.000 claims description 15
- 229960000935 dehydrated alcohol Drugs 0.000 claims description 14
- 239000002244 precipitate Substances 0.000 claims description 14
- 238000001556 precipitation Methods 0.000 claims description 14
- 239000000047 product Substances 0.000 claims description 14
- 230000001105 regulatory effect Effects 0.000 claims description 13
- 229960000583 acetic acid Drugs 0.000 claims description 11
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 8
- 238000005119 centrifugation Methods 0.000 claims description 7
- 239000012141 concentrate Substances 0.000 claims description 7
- 239000008367 deionised water Substances 0.000 claims description 7
- 229910021641 deionized water Inorganic materials 0.000 claims description 7
- 238000004090 dissolution Methods 0.000 claims description 7
- 238000004821 distillation Methods 0.000 claims description 7
- 230000002255 enzymatic effect Effects 0.000 claims description 7
- 239000012467 final product Substances 0.000 claims description 7
- 230000008014 freezing Effects 0.000 claims description 7
- 238000007710 freezing Methods 0.000 claims description 7
- 230000007062 hydrolysis Effects 0.000 claims description 7
- 238000006460 hydrolysis reaction Methods 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 7
- 238000002203 pretreatment Methods 0.000 claims description 7
- 102000004169 proteins and genes Human genes 0.000 claims description 7
- 108090000623 proteins and genes Proteins 0.000 claims description 7
- 238000000926 separation method Methods 0.000 claims description 7
- 238000010792 warming Methods 0.000 claims description 7
- 238000005406 washing Methods 0.000 claims description 7
- 239000012362 glacial acetic acid Substances 0.000 claims description 5
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 4
- FMRLDPWIRHBCCC-UHFFFAOYSA-L Zinc carbonate Chemical compound [Zn+2].[O-]C([O-])=O FMRLDPWIRHBCCC-UHFFFAOYSA-L 0.000 claims description 4
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 claims description 4
- 239000011667 zinc carbonate Substances 0.000 claims description 4
- 235000004416 zinc carbonate Nutrition 0.000 claims description 4
- 229910000010 zinc carbonate Inorganic materials 0.000 claims description 4
- 239000011746 zinc citrate Substances 0.000 claims description 4
- 235000006076 zinc citrate Nutrition 0.000 claims description 4
- 229940068475 zinc citrate Drugs 0.000 claims description 4
- 102000005158 Subtilisins Human genes 0.000 claims description 3
- 108010056079 Subtilisins Proteins 0.000 claims description 3
- 241000276707 Tilapia Species 0.000 claims description 3
- 239000013505 freshwater Substances 0.000 claims description 3
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 2
- 229960000314 zinc acetate Drugs 0.000 claims description 2
- 229940043825 zinc carbonate Drugs 0.000 claims description 2
- 239000011670 zinc gluconate Substances 0.000 claims description 2
- 235000011478 zinc gluconate Nutrition 0.000 claims description 2
- 229960000306 zinc gluconate Drugs 0.000 claims description 2
- 229960001296 zinc oxide Drugs 0.000 claims description 2
- 239000011573 trace mineral Substances 0.000 abstract description 11
- 235000013619 trace mineral Nutrition 0.000 abstract description 11
- 239000013589 supplement Substances 0.000 abstract description 6
- 229940024606 amino acid Drugs 0.000 description 12
- 235000001014 amino acid Nutrition 0.000 description 11
- 150000001413 amino acids Chemical class 0.000 description 11
- 238000000034 method Methods 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 6
- 235000018102 proteins Nutrition 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 4
- 239000013522 chelant Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000000227 grinding Methods 0.000 description 4
- 241000270666 Testudines Species 0.000 description 3
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 208000019926 Keshan disease Diseases 0.000 description 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 230000009469 supplementation Effects 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- RJFAYQIBOAGBLC-UHFFFAOYSA-N 2-amino-4-methylselanyl-butanoic acid Chemical compound C[Se]CCC(N)C(O)=O RJFAYQIBOAGBLC-UHFFFAOYSA-N 0.000 description 1
- 108091005658 Basic proteases Proteins 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- 206010039921 Selenium deficiency Diseases 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000005903 acid hydrolysis reaction Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003035 anti-peroxidant effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000002152 aqueous-organic solution Substances 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 229960002989 glutamic acid Drugs 0.000 description 1
- 108010067216 glycyl-glycyl-glycine Proteins 0.000 description 1
- XKUKSGPZAADMRA-UHFFFAOYSA-N glycyl-glycyl-glycine Natural products NCC(=O)NCC(=O)NCC(O)=O XKUKSGPZAADMRA-UHFFFAOYSA-N 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 150000002742 methionines Chemical class 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical compound OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000013535 sea water Substances 0.000 description 1
- 229940065287 selenium compound Drugs 0.000 description 1
- 150000003343 selenium compounds Chemical class 0.000 description 1
- NLKSSCOPUYXQPS-UHFFFAOYSA-N selenonyl dichloride Chemical compound Cl[Se](Cl)(=O)=O NLKSSCOPUYXQPS-UHFFFAOYSA-N 0.000 description 1
- 239000003352 sequestering agent Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- JBQYATWDVHIOAR-UHFFFAOYSA-N tellanylidenegermanium Chemical compound [Te]=[Ge] JBQYATWDVHIOAR-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
- B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
- B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D34/00—Containers or accessories specially adapted for handling liquid toiletry or cosmetic substances, e.g. perfumes
- A45D34/04—Appliances specially adapted for applying liquid, e.g. using roller or ball
- A45D34/042—Appliances specially adapted for applying liquid, e.g. using roller or ball using a brush or the like
- A45D34/045—Appliances specially adapted for applying liquid, e.g. using roller or ball using a brush or the like connected to the cap of the container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
- B65D51/28—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
- B65D51/2807—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
-
- A—HUMAN NECESSITIES
- A45—HAND OR TRAVELLING ARTICLES
- A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
- A45D2200/00—Details not otherwise provided for in A45D
- A45D2200/05—Details of containers
- A45D2200/054—Means for supplying liquid to the outlet of the container
- A45D2200/055—Piston or plunger for supplying the liquid to the applicator
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Biochemistry (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Mycology (AREA)
- Marine Sciences & Fisheries (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
Abstract
Description
Claims (8)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410336871.0A CN104095242B (zh) | 2014-07-15 | 2014-07-15 | 一种复合锌硒多肽化合物及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410336871.0A CN104095242B (zh) | 2014-07-15 | 2014-07-15 | 一种复合锌硒多肽化合物及其制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104095242A CN104095242A (zh) | 2014-10-15 |
| CN104095242B true CN104095242B (zh) | 2016-04-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410336871.0A Active CN104095242B (zh) | 2014-07-15 | 2014-07-15 | 一种复合锌硒多肽化合物及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104095242B (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105768111A (zh) * | 2016-04-18 | 2016-07-20 | 厦门三九生物科技有限公司 | 一种海洋多肽-钙螯合物的制备方法与应用 |
| CN105852134A (zh) * | 2016-04-18 | 2016-08-17 | 厦门三九生物科技有限公司 | 一种海洋多肽-锌螯合物的制备方法与应用 |
| CN105876809A (zh) * | 2016-04-18 | 2016-08-24 | 厦门三九生物科技有限公司 | 一种海洋多肽-硒螯合物的制备方法与应用 |
| CN107502642A (zh) * | 2017-08-24 | 2017-12-22 | 浦江县美泽生物科技有限公司 | 一种鱼蛋白小肽螯合锌 |
| CN110423791A (zh) * | 2019-08-06 | 2019-11-08 | 广州大学 | 一种还原性蛋白多肽及其制备方法和应用 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1146449A (zh) * | 1994-08-15 | 1997-04-02 | 常达正 | 氨基酸锌的制备方法及其应用 |
| CN1184776A (zh) * | 1997-05-06 | 1998-06-17 | 合肥经济技术学院 | 活性红色单质硒的制备方法 |
| CN1388094A (zh) * | 2001-05-26 | 2003-01-01 | 杨杰民 | 富硒氨基酸及其生产方法 |
| CN1560034A (zh) * | 2004-02-24 | 2005-01-05 | 洪作鹏 | 一种新型有机硒的制备工艺 |
| CN1720249A (zh) * | 2002-12-05 | 2006-01-11 | Md白奥阿尔法有限公司 | 氨基酸螯合物的制备方法 |
| CN101283805A (zh) * | 2008-05-22 | 2008-10-15 | 广州大学 | 一种锌-多肽配合物及其制备方法和应用 |
| CN103145495A (zh) * | 2013-02-27 | 2013-06-12 | 谢超 | 一种高能复合肽化蛋白硒营养液、其制备方法和用途 |
-
2014
- 2014-07-15 CN CN201410336871.0A patent/CN104095242B/zh active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1146449A (zh) * | 1994-08-15 | 1997-04-02 | 常达正 | 氨基酸锌的制备方法及其应用 |
| CN1184776A (zh) * | 1997-05-06 | 1998-06-17 | 合肥经济技术学院 | 活性红色单质硒的制备方法 |
| CN1388094A (zh) * | 2001-05-26 | 2003-01-01 | 杨杰民 | 富硒氨基酸及其生产方法 |
| CN1720249A (zh) * | 2002-12-05 | 2006-01-11 | Md白奥阿尔法有限公司 | 氨基酸螯合物的制备方法 |
| CN1560034A (zh) * | 2004-02-24 | 2005-01-05 | 洪作鹏 | 一种新型有机硒的制备工艺 |
| CN101283805A (zh) * | 2008-05-22 | 2008-10-15 | 广州大学 | 一种锌-多肽配合物及其制备方法和应用 |
| CN103145495A (zh) * | 2013-02-27 | 2013-06-12 | 谢超 | 一种高能复合肽化蛋白硒营养液、其制备方法和用途 |
Non-Patent Citations (4)
| Title |
|---|
| Zn(Ⅱ)-大豆多肽配合物的合成;许庆陵等;《食品科技》;20081231(第08期);31-34 * |
| 多肽-锌配合物对奥尼罗非鱼生长性能和血清生化指标的影响;郭存荣等;《中国饲料》;20101231(第23期);35-37 * |
| 富硒菜籽蛋白肽的制备工艺研究;刘大川等;《中国粮油学报》;20060630;第21卷(第03期);245-249 * |
| 硒-乳蛋白活性肽开发及应用前景;徐明芳等;《中国乳业》;20101231(第09期);80-82 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104095242A (zh) | 2014-10-15 |
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