CN104083592B - A kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines - Google Patents

A kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines Download PDF

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CN104083592B
CN104083592B CN201410362670.8A CN201410362670A CN104083592B CN 104083592 B CN104083592 B CN 104083592B CN 201410362670 A CN201410362670 A CN 201410362670A CN 104083592 B CN104083592 B CN 104083592B
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parts
medicine
filtrate
decocted
obtains
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CN201410362670.8A
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CN104083592A (en
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李晓冰
李莎莎
刘现辉
董文杰
李宁
程凯
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河南中医学院
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Abstract

The present invention relates to the Externally applied Chinese medicine liquid for the treatment of phlebitis caused by chemotherapeutic medicines, the problem of effectively can solving phlebitis caused by chemotherapeutic medicines, its technical scheme solved is made up of the material medicine of following parts by weight meter:8 20 parts of 10 40 parts of purslane, 10 30 parts of cordate houttuynia, 6 20 parts of tinosporae, 10 40 parts of selfheal, 10 30 parts of the capsule of weeping forsythia, 6 15 parts of Resina Draconis, 10 20 parts of safflower, 6 20 parts of rhodiola root, 6 20 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, the present invention has promoting blood circulation and removing blood stasis, it is clearing heat and detoxicating, the effect of dispersing swelling and dissipating binds, suitable for the treatment of phlebitis caused by chemotherapeutic medicines, patient's pain can be mitigated, ensure that chemotherapy is smoothed out, prepare simple, cheap, convenient material drawing, it is used conveniently and safely, is to treat the innovation on phlebitis caused by chemotherapeutic medicines medicine.

Description

A kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines

Technical field

The present invention relates to medicine, particularly a kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines.

Background technology

Chemotherapy be advanced malignant tumor often one of with therapeutic scheme, most chemotherapy regimens are both needed to repeated multiple times note through vein Penetrate, chemotherapy-induced phlebitis different degrees of Chang Bingfa, pain, redness occur for injection vein, the symptom such as be hardened, and increase patient suffering And influence the progress of therapeutic scheme.Although intravenous chemotherapy infusion techniques are significantly improved earlier above, reduce or prevent to a certain extent The generation of chemotherapeutics extravasation, but due to needing chemotherapy of tumors repeated multiple times Large Dose Intravenous to be administered, chemotherapy-induced phlebitis morbidity. more Rate is still higher.Therefore, both can guarantee that chemotherapy was smoothed out, patients undergoing chemotherapy vein protected again, prevent the appearance of phlebitis just into For a problem in chemotherapy of tumors, in this regard, traditional Chinese medicine has irreplaceable, unique advantage.Therefore, how to utilize Chinese medicine treats the problem of phlebitis caused by chemotherapeutic medicines is current urgent need to resolve.

The content of the invention

For above-mentioned situation, to solve the defect of prior art, the purpose of the present invention is just to provide one kind and treats chemotherapeutic The phlebitis caused Externally applied Chinese medicine liquid of thing, the problem of effectively can solving phlebitis caused by chemotherapeutic medicines.

The technical scheme that the present invention is solved is made up of the material medicine of following parts by weight meter:Purslane 10-40 Part, 10-30 parts of cordate houttuynia, 6-20 parts of tinosporae, 10-40 parts of selfheal, 10-30 parts of the capsule of weeping forsythia, 6-15 parts of Resina Draconis, safflower 10- 8-20 parts of 20 parts, 6-20 parts of rhodiola root, 6-20 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, above-mentioned raw materials medicine is mixed, and add water leaching Not yet, after being fried boiling, slow fire is decocted 30~60 minutes again, filtering, obtains the first filtrate, the dregs of a decoction add water, and is submerged, after being fried boiling, slow fire is decocted again Boil 30 minutes, filter, obtain the second filtrate, merge filtrate twice, mix, herb liquid is obtained, in use, during sterile gauze block is inserted Infiltrated in decoction, the sterile gauze block for being impregnated with herb liquid is spread on into affected part.

The present invention have it is promoting blood circulation and removing blood stasis, it is clearing heat and detoxicating, the effect of dispersing swelling and dissipating binds.Suitable for phlebitis caused by chemotherapeutic medicines Treatment, can mitigate patient's pain, ensure that chemotherapy is smoothed out, and prepare simple, cheap, convenient material drawing is used conveniently and safely, It is to treat the innovation on phlebitis caused by chemotherapeutic medicines medicine.

Embodiment

The embodiment to the present invention is described in further detail with reference to embodiments.

Embodiment 1

In the specific implementation, Externally applied Chinese medicine liquid of the present invention can be made up of the material medicine of following parts by weight meter:Purslane 25 parts, 20 parts of cordate houttuynia, 13 parts of tinosporae, 25 parts of selfheal, 20 parts of the capsule of weeping forsythia, 10 parts of Resina Draconis, 15 parts of safflower, rhodiola root 13 14 parts of part, 13 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, above-mentioned raw materials medicine is mixed, added water to submerge, after being fried boiling, slow fire is decocted again 45 minutes, filtering obtained the first filtrate, the dregs of a decoction add water, and submerges, after being fried boiling, slow fire is decocted 30 minutes again, and filtering obtains the second filtrate, Merge filtrate twice, mix, obtain herb liquid, infiltrated in use, sterile gauze block is inserted in herb liquid, herb liquid will be impregnated with Sterile gauze block soak in affected part.

Embodiment 2

In the specific implementation, Externally applied Chinese medicine liquid of the present invention can be made up of the material medicine of following parts by weight meter:Purslane 10 parts, it is 10 parts of cordate houttuynia, 6 parts of tinosporae, 10 parts of selfheal, 10 parts of the capsule of weeping forsythia, 6 parts of Resina Draconis, 10 parts of safflower, 6 parts of rhodiola root, swollen 8 parts of 6 parts of wind and nakedcaule groundsel are saved, above-mentioned raw materials medicine is mixed, added water to submerge, after being fried boiling, slow fire is decocted 30 minutes again, Filtering, obtains the first filtrate, the dregs of a decoction add water, and submerges, after being fried boiling, slow fire is decocted 30 minutes again, and filtering obtains the second filtrate, merges two Secondary filtrate, mixes, obtains herb liquid, is infiltrated in use, sterile gauze block is inserted in herb liquid, will be impregnated with the sterile of herb liquid Gauze piece soak is in affected part.

Embodiment 3

In the specific implementation, Externally applied Chinese medicine liquid of the present invention can be made up of the material medicine of following parts by weight meter:Purslane 40 parts, 30 parts of cordate houttuynia, 20 parts of tinosporae, 40 parts of selfheal, 30 parts of the capsule of weeping forsythia, 15 parts of Resina Draconis, 20 parts of safflower, rhodiola root 20 20 parts of part, 20 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, above-mentioned raw materials medicine is mixed, added water to submerge, after being fried boiling, slow fire is decocted again 60 minutes, filtering obtained the first filtrate, the dregs of a decoction add water, and submerges, after being fried boiling, slow fire is decocted 30 minutes again, and filtering obtains the second filtrate, Merge filtrate twice, mix, obtain herb liquid, infiltrated in use, sterile gauze block is inserted in herb liquid, herb liquid will be impregnated with Sterile gauze block soak in affected part.

Embodiment 4

In the specific implementation, it is made up of the material medicine of following parts by weight meter:11-20 parts of purslane, cordate houttuynia 11- 19 parts, 7-14 parts of tinosporae, 11-20 parts of selfheal, 11-19 parts of the capsule of weeping forsythia, 7-9 parts of Resina Draconis, 11-14 parts of safflower, rhodiola root 7- 9-13 parts of 12 parts, 7-12 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, above-mentioned raw materials medicine is mixed, added water to submerge, after being fried boiling, slow fire Decoct again 30~60 minutes, filter, obtain the first filtrate, the dregs of a decoction add water, submerge, after being fried boiling, slow fire is decocted 30 minutes again, filtering, The second filtrate is obtained, merges filtrate twice, mixes, obtains herb liquid, is infiltrated in use, sterile gauze block is inserted in herb liquid, will The sterile gauze block soak of herb liquid is impregnated with affected part.

Embodiment 5

In the specific implementation, it is made up of the material medicine of following parts by weight meter:21-39 parts of purslane, cordate houttuynia 21- 29 parts, 15-19 parts of tinosporae, 21-39 parts of selfheal, 21-29 parts of the capsule of weeping forsythia, 11-14 parts of Resina Draconis, 16-19 parts of safflower, rhodiola root 15-19 parts of 14-19 parts, 14-19 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, above-mentioned raw materials medicine is mixed, added water to submerge, is fried boiling Afterwards, slow fire is decocted 30~60 minutes again, filtering, obtains the first filtrate, the dregs of a decoction add water, and is submerged, after being fried boiling, slow fire decocts 30 points again Clock, filtering obtains the second filtrate, merges filtrate twice, mixes, herb liquid is obtained, in use, sterile gauze block is inserted in herb liquid Infiltration, will be impregnated with the sterile gauze block soak of herb liquid in affected part.

The optimal case study on implementation of the present invention is the foregoing is only, is merely illustrative for the purpose of the present invention, and it is unrestricted Property, those skilled in the art understands, can carry out some to it in the scope of the claims in the present invention and be equal or wait The replacement of effect or replacement, it is substantially identical, belong to protection scope of the present invention.

The present invention has rapid-action, and curative effect is stable, and patient compliance is good, is effectively improved phlebitis after chemotherapy and occurs and be in progress The advantages of.It is satisfied with through clinical trial result, relevant information is as follows:

1st, case selection:

Clinic randomly selects 72 patients that chemotherapy-induced phlebitis is produced because of Doxorubicin, and 72 patients are pressed into random digit Method is divided into prescription external application group (treatment group) 35 of the present invention, 50% magnesium sulfate external application group (control group) 37.Two groups of sexes, years Age, site of puncture, remaining needle species compare, not statistically significant (P > 0.05).The clinical data of patient is shown in Table 1.

The treatment group of table 1 and the clinical physical data of control group compare

2nd, therapeutic scheme:

Control group:50% magnesium sulfate is given fully to infiltrate after sterile yarn block, soak affected part is wrapped up, area is more than with preservative film Pain redness area, soak 2h, 3 times/d.Treatment group:Fully infiltrated after sterile yarn block with herb liquid of the present invention, soak affected part, with guarantor Fresh film parcel, area is more than the red and swollen area of pain, soak 2h, 3 times/d.Two groups were continuously observed its curative effect using 10 days.

3rd, [observation of curative effect [J] nursings of Chen Xiu outstanding person's anti-inflammatory analgesic cream outer patch treatment phlebitis are miscellaneous for curative effect determinate standard Will, 2006,21 (21):361]:Evaluate the curative effect after one course for the treatment of of treatment.Recovery from illness:Local organization redness disappears, and vascular wall becomes Soft, elasticity is recovered, vascular patency.Effectively:Local organization redness mitigates, pain relief.It is invalid:Pain is local red and swollen without alleviation Without significant change, or even aggravate.

4th, statistical procedures:

The total effective rate of control group and treatment group's treatment chemotherapy-induced phlebitis is respectively 78.4%, 94.3%.Illustrate this hair Bright composition determined curative effect, is specifically shown in Table 2.

The treatment group of table 2 and control group Clinical efficacy comparison

4th, conclusion:

The present invention have it is promoting blood circulation and removing blood stasis, it is clearing heat and detoxicating, the effect of dispersing swelling and dissipating binds.Suitable for phlebitis caused by chemotherapeutic medicines Treatment, can mitigate patient's pain, ensure that chemotherapy is smoothed out, and prepare simple, cheap, convenient material drawing is used conveniently and safely, Clinical practice effective percentage up to more than 94%, is to treat the innovation on phlebitis caused by chemotherapeutic medicines medicine, faces with actual Bed meaning.

Claims (5)

1. a kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines, it is characterised in that by the original of following parts by weight meter Material medicine is made:It is 25 parts of purslane, 20 parts of cordate houttuynia, 13 parts of tinosporae, 25 parts of selfheal, 20 parts of the capsule of weeping forsythia, 10 parts of Resina Draconis, red Spend 15 parts, 13 parts of rhodiola root, 14 parts of 13 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, above-mentioned raw materials medicine is mixed, added water to submerge, is decocted After boiling, slow fire is decocted 45 minutes again, filtering, obtains the first filtrate, the dregs of a decoction add water, and is submerged, after being fried boiling, slow fire is decocted 30 minutes again, Filtering, obtains the second filtrate, merges filtrate twice, mixes, obtains herb liquid, is soaked in use, sterile gauze block is inserted in herb liquid Profit, will be impregnated with the sterile gauze block soak of herb liquid in affected part.
2. a kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines, it is characterised in that by the original of following parts by weight meter Material medicine is made:10 parts of purslane, 10 parts of cordate houttuynia, 6 parts of tinosporae, 10 parts of selfheal, 10 parts of the capsule of weeping forsythia, 6 parts of Resina Draconis, safflower 8 parts of 10 parts, 6 parts of rhodiola root, 6 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, above-mentioned raw materials medicine is mixed, added water to submerge, after being fried boiling, Slow fire is decocted 30 minutes again, filtering, obtains the first filtrate, the dregs of a decoction add water, and is submerged, after being fried boiling, slow fire is decocted 30 minutes again, filtering, The second filtrate is obtained, merges filtrate twice, mixes, obtains herb liquid, is infiltrated in use, sterile gauze block is inserted in herb liquid, will The sterile gauze block soak of herb liquid is impregnated with affected part.
3. a kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines, it is characterised in that by the original of following parts by weight meter Material medicine is made:It is 40 parts of purslane, 30 parts of cordate houttuynia, 20 parts of tinosporae, 40 parts of selfheal, 30 parts of the capsule of weeping forsythia, 15 parts of Resina Draconis, red Spend 20 parts, 20 parts of rhodiola root, 20 parts of 20 parts of Glabrous Sarcandra Herb and nakedcaule groundsel, above-mentioned raw materials medicine is mixed, added water to submerge, is decocted After boiling, slow fire is decocted 60 minutes again, filtering, obtains the first filtrate, the dregs of a decoction add water, and is submerged, after being fried boiling, slow fire is decocted 30 minutes again, Filtering, obtains the second filtrate, merges filtrate twice, mixes, obtains herb liquid, is soaked in use, sterile gauze block is inserted in herb liquid Profit, will be impregnated with the sterile gauze block soak of herb liquid in affected part.
4. a kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines, it is characterised in that by the original of following parts by weight meter Material medicine is made:11-20 parts of purslane, 11-19 parts of cordate houttuynia, 7-14 parts of tinosporae, 11-20 parts of selfheal, capsule of weeping forsythia 11-19 Part, 7-9 parts of Resina Draconis, 11-14 parts of safflower, 7-12 parts of rhodiola root, 7-12 parts of Glabrous Sarcandra Herb and 9-13 parts of nakedcaule groundsel, by above-mentioned raw materials Medicine is mixed, and is added water to submerge, after being fried boiling, and slow fire is decocted 30~60 minutes again, filtering, obtains the first filtrate, the dregs of a decoction add water, Submergence, after being fried boiling, slow fire is decocted 30 minutes again, filtering, obtains the second filtrate, merges filtrate twice, is mixed, is obtained herb liquid, use When, sterile gauze block is inserted in herb liquid and infiltrated, the sterile gauze block soak of herb liquid will be impregnated with affected part.
5. a kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines, it is characterised in that by the original of following parts by weight meter Material medicine is made:21-39 parts of purslane, 21-29 parts of cordate houttuynia, 15-19 parts of tinosporae, 21-39 parts of selfheal, capsule of weeping forsythia 21-29 Part, 11-14 parts of Resina Draconis, 16-19 parts of safflower, 14-19 parts of rhodiola root, 14-19 parts of Glabrous Sarcandra Herb and 15-19 parts of nakedcaule groundsel, will be upper State material medicine to mix, add water to submerge, after being fried boiling, slow fire is decocted 30~60 minutes again, filter, obtain the first filtrate, medicine Slag is added water, submergence, and after being fried boiling, slow fire is decocted 30 minutes again, and filtering obtains the second filtrate, merges filtrate twice, mixes, obtains Chinese medicine Liquid, infiltrates in use, sterile gauze block is inserted in herb liquid, will be impregnated with the sterile gauze block soak of herb liquid in affected part.
CN201410362670.8A 2014-07-28 2014-07-28 A kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines CN104083592B (en)

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CN102488790A (en) * 2011-12-11 2012-06-13 孙爱莲 External Chinese traditional medicine transfusion plaster for preventing and treating phlebitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003105839A1 (en) * 2002-06-18 2003-12-24 Biopartners Gmbh Use of ribavirin for producing a pharmaceutical composition directed against bunyaviridae
CN101926868A (en) * 2010-09-06 2010-12-29 韩淑红 External traditional Chinese medicine for preventing and treating phlebitis caused by chemotherapeutic medicines
CN102488790A (en) * 2011-12-11 2012-06-13 孙爱莲 External Chinese traditional medicine transfusion plaster for preventing and treating phlebitis

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