CN101926868B - External traditional Chinese medicine for preventing and treating phlebitis caused by chemotherapeutic medicines - Google Patents
External traditional Chinese medicine for preventing and treating phlebitis caused by chemotherapeutic medicines Download PDFInfo
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- CN101926868B CN101926868B CN2010102724391A CN201010272439A CN101926868B CN 101926868 B CN101926868 B CN 101926868B CN 2010102724391 A CN2010102724391 A CN 2010102724391A CN 201010272439 A CN201010272439 A CN 201010272439A CN 101926868 B CN101926868 B CN 101926868B
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Abstract
The invention relates to an external traditional Chinese medicine for preventing and treating phlebitis caused by chemotherapeutic medicines. The external traditional Chinese medicine consists of the following raw material medicines in part by weight: 40 to 80 parts of sanguisorba carbon, 30 to 60 parts of weeping forsythia, 30 to 60 parts of rhubarb, 40 to 80 parts of cutch, and 40 to 60 parts of borneol. The external traditional Chinese medicine is prepared by the following steps of: crushing the raw material medicines respectively, and sieving the medicines through a 200-mesh screen respectively to obtain powder of each raw material medicine; selecting the powder according to the weight proportion of each raw material in the external traditional Chinese medicine formula, mixing the powder, and uniformly blending to obtain traditional Chinese medicine powder; and blending the traditional Chinese medicine powder with sesame oil to prepare uniform paste, applying the paste at an intravenous injection position externally, binding with a bandage, performing chemotherapy, and releasing the bandage after the chemotherapy is completed. The external traditional Chinese medicine has the advantages of simple preparation, low cost, wide medicine sources, convenient use, quick response, high cure rate and no toxic or side effect, is suitable for preventing and treating the phlebitis caused by the chemotherapeutic medicines, and has the clinical application effective rate of 98.15 percent.
Description
Technical field
The present invention relates to a kind of medicine of treating phlebitis caused by chemotherapeutic medicines, be specifically related to the external Chinese medicine of a kind of prevention and treatment phlebitis caused by chemotherapeutic medicines.
Background technology
Chemotherapy occupies critical role in treating malignant tumor, it is through kill the therapy of cancerous cell with cell toxicity medicament as a kind of Therapeutic Method of general.At present, new drug continues to bring out, the extensive use of rational and effective Combination chemotherapy greatly improves the curative effect of chemotherapy, has become the main treatment means of a lot of tumors.But intravenously administrable is the main path that chemotherapeutics is taken in, and in chemotherapeutical process, can cause damage to normal structure inevitably, and many chemotherapeutics have serious toxicity and zest to normal structure.One of main adverse reaction is exactly a phlebitis, and phlebitic clinically incidence rate can reach about 80%, and this has brought great misery to patient, and the lighter causes patient's pain, severe patient so and TD.Phlebitis be multiple reason cause occur in the struvite pathological changes of venous; During clinical intravenous drip the most commonly treatment because of repeated localised puncture vein or caused inflammation of vein of instillation medicine irritation and thrombophlebitis; Clinical mainly showing as injected the used vein of chemotherapeutic position pain, skin rubefaction; Can be the hardening of rope strip along vein cutaneous pigmentation, vascular later on, severe patient causes venous thrombosis.In recent years; The incidence rate of primary disease is progressively ascendant trend, but does not still have effective method treatment both at home and abroad, and some drug price costliness and effect are unsatisfactory; In a single day in chemotherapy process, the clinical treatment that phlebitis caused by chemotherapeutic medicines will influence tumor patient occurs, cause serious consequence.
Summary of the invention
The objective of the invention is to solve the problems referred to above that exist in the prior art; In order effectively to prevent and the treatment phlebitis caused by chemotherapeutic medicines; The present invention is according to theory of Chinese medical science; Through drug screening and clinical verification repeatedly, a kind of determined curative effect, cheap, safe and effective, easy to use, the external Chinese medicine that can prevent and treat phlebitis caused by chemotherapeutic medicines that has no side effect are provided.
The present invention addresses the above problem to adopt following technical scheme:
The invention provides the external Chinese medicine of a kind of prevention and treatment phlebitis caused by chemotherapeutic medicines, it is characterized in that forming: charred Radix Sanguisorbae 40-80 part, Fructus Forsythiae 30-60 part, Radix Et Rhizoma Rhei 30-60 part, catechu 40-80 part, Borneolum Syntheticum 40-60 part by following raw materials in weight portion medicine.
Preferable range of the present invention is: 50 parts of charred Radix Sanguisorbae, 50 parts of Fructus Forsythiaes, 50 parts of Radix Et Rhizoma Rhei, 50 parts in catechu, 50 parts of Borneolum Syntheticums.
The invention provides above-mentioned external preparation method of Chinese medicine: by external raw material of Chinese medicine medicine prescription proportioning; The above-mentioned crude drug pulverize separately of respectively distinguishing the flavor of is become 200 order medicated powder; According to the weight portion proportioning of each crude drug in the external Chinese prescription powder of getting it filled; Medicated powder is mixed, and modulation evenly promptly gets Chinese medicine powder, and it is subsequent use to bottle.
The method for using of external Chinese medicine of the present invention: the above-mentioned Chinese medicine powder that makes is deployed into uniform pasty state external application in intravenous injection place with Oleum sesami, bandages, carry out chemotherapy again, behind end of chemotherapy, remove bandaging.Before each chemotherapy, bring into use until end of chemotherapy.
The present invention also provides the purposes of above-mentioned external Chinese medicine in preparation prevention and the caused phlebitic medicine of treatment chemotherapeutics.
The present invention has following advantage:
External Chinese medicine preparation of the present invention is simple, and cost is low, the medicine source is wide, easy to use, and curative effect is fast, and cure rate is high, and is without any side effects, is applicable to the prevention and the treatment of phlebitis caused by chemotherapeutic medicines, uses effective percentage clinically and reaches 98.15%.
The specific embodiment
Below in conjunction with embodiment the present invention is described further.
Embodiment 1: the external Chinese medicine of a kind of prevention and treatment phlebitis caused by chemotherapeutic medicines, the weight portion of material medicine is 50 parts of charred Radix Sanguisorbae, 50 parts of Fructus Forsythiaes, 50 parts of Radix Et Rhizoma Rhei, 50 parts in catechu, 50 parts of Borneolum Syntheticums.By external raw material of Chinese medicine medicine prescription proportioning, the above-mentioned crude drug of respectively distinguishing the flavor of is pulverized respectively, crossed 200 mesh sieves, obtain the medicated powder of each crude drug; According to the weight portion proportioning of each crude drug in the external Chinese prescription powder of getting it filled; Medicated powder is mixed, and modulation evenly makes Chinese medicine powder.The above-mentioned Chinese medicine powder that makes is deployed into uniform pasty state external application in intravenous injection place with Oleum sesami, bandages, carry out chemotherapy again, behind end of chemotherapy, remove bandaging, before each chemotherapy, bring into use until end of chemotherapy.
Clinical observation on the therapeutic effect data: pulmonary carcinoma 20 examples, breast carcinoma 20 examples, wherein male's 20 examples; Women's 20 examples; All patients all confirm that through pathology and iconography 33 routine vein position pain, skin rubefaction are phlebitis caused by chemotherapeutic medicines after diagnosing behind the treatment with chemotherapy medicine; Use and cure 18 examples after the application of above-mentioned external Chinese medicine, symptom 12 examples that take a turn for the better.
Embodiment 2: the external Chinese medicine of a kind of prevention and treatment phlebitis caused by chemotherapeutic medicines, the weight portion of material medicine is 40 parts of charred Radix Sanguisorbae, 60 parts of Fructus Forsythiaes, 30 parts of Radix Et Rhizoma Rhei, 60 parts in catechu, 40 parts of Borneolum Syntheticums.By external raw material of Chinese medicine medicine prescription proportioning, the above-mentioned crude drug of respectively distinguishing the flavor of is pulverized respectively, crossed 200 mesh sieves, obtain the medicated powder of each crude drug; According to the weight portion proportioning of each crude drug in the external Chinese prescription powder of getting it filled; Medicated powder is mixed, and modulation evenly makes Chinese medicine powder.The above-mentioned Chinese medicine powder that makes is deployed into uniform pasty state external application in intravenous injection place with Oleum sesami, bandages, carry out chemotherapy again, behind end of chemotherapy, remove bandaging, before each chemotherapy, bring into use until end of chemotherapy.
Clinical observation on the therapeutic effect data: hepatocarcinoma 30 examples, rectal cancer 20 examples, gastric cancer 15 examples; Male's 35 examples wherein, women's 30 examples, all patients all confirm through pathology and iconography; 56 routine vein position pain, skin rubefaction behind the treatment with chemotherapy medicine; Be phlebitis caused by chemotherapeutic medicines after diagnosing, after using the application of above-mentioned external Chinese medicine, cure 35 examples, symptom 17 examples that take a turn for the better.
Embodiment 3: the external Chinese medicine of a kind of prevention and treatment phlebitis caused by chemotherapeutic medicines, the weight portion of material medicine is 80 parts of charred Radix Sanguisorbae, 30 parts of Fructus Forsythiaes, 60 parts of Radix Et Rhizoma Rhei, 80 parts in catechu, 60 parts of Borneolum Syntheticums.By external raw material of Chinese medicine medicine prescription proportioning, the above-mentioned crude drug of respectively distinguishing the flavor of is pulverized respectively, crossed 200 mesh sieves, obtain the medicated powder of each crude drug; According to the weight portion proportioning of each crude drug in the external Chinese prescription powder of getting it filled; Medicated powder is mixed, and modulation evenly makes Chinese medicine powder.The above-mentioned Chinese medicine powder that makes is deployed into uniform pasty state external application in intravenous injection place with Oleum sesami, bandages, carry out chemotherapy again, behind end of chemotherapy, remove bandaging, before each chemotherapy, bring into use until end of chemotherapy.
Clinical observation on the therapeutic effect data: nonsmall-cell lung cancer 10 examples, mammary cancer 15 examples, rectal cancer 12 examples; Gastric cancer 18 examples, male's 25 examples wherein, women's 30 examples; All patients all confirm that through pathology and iconography 48 routine vein position pain, skin rubefaction are phlebitis caused by chemotherapeutic medicines after diagnosing behind the treatment with chemotherapy medicine; After using the application of above-mentioned external Chinese medicine, cure 30 examples, symptom 15 examples that take a turn for the better.
Embodiment 4: the external Chinese medicine clinical observation on the therapeutic effect data of a kind of prevention and treatment phlebitis caused by chemotherapeutic medicines:
1, case is selected:
Clinical picked at random 118 routine malignant tumor chemotherapy patients, all patients all confirm through pathology and iconography, male's 60 examples wherein, and women's 58 examples, 108 routine vein position pain, skin rubefaction are phlebitis caused by chemotherapeutic medicines after diagnosing behind the treatment with chemotherapy medicine.
2, Therapeutic Method:
The external Chinese medicine powder that the foregoing description 1-3 is prepared is deployed into uniform pasty state external application in intravenous injection place with Oleum sesami; Bandage, carry out chemotherapy again, behind end of chemotherapy; Remove bandaging, before each chemotherapy, bring into use until end of chemotherapy.
3, curative effect judging standard:
Cure: symptom complete obiterations such as vein position pain, skin rubefaction;
Take a turn for the better: symptoms such as vein position pain, skin rubefaction partly disappear or alleviate to some extent;
Invalid: symptoms such as vein position pain, skin rubefaction do not have any improvement.
4, therapeutic outcome:
Treat 108 routine patients, cure 58 examples, 48 examples that take a turn for the better, invalid 2 examples, total effective rate (promptly curing improvement rate) reaches 98.15%.
Claims (7)
1. an external Chinese medicine that prevents and treat phlebitis caused by chemotherapeutic medicines is characterized in that being made up of following raw materials in weight portion medicine: charred Radix Sanguisorbae 40-80 part, Fructus Forsythiae 30-60 part, Radix Et Rhizoma Rhei 30-60 part, catechu 40-80 part, Borneolum Syntheticum 40-60 part.
2. the external Chinese medicine of prevention according to claim 1 and treatment phlebitis caused by chemotherapeutic medicines is characterized in that being made up of following raw materials in weight portion medicine: 50 parts of charred Radix Sanguisorbae, 50 parts of Fructus Forsythiaes, 50 parts of Radix Et Rhizoma Rhei, 50 parts in catechu, 50 parts of Borneolum Syntheticums.
3. the external Chinese medicine of prevention according to claim 1 and treatment phlebitis caused by chemotherapeutic medicines is characterized in that being made up of following raw materials in weight portion medicine: 40 parts of charred Radix Sanguisorbae, 60 parts of Fructus Forsythiaes, 30 parts of Radix Et Rhizoma Rhei, 60 parts in catechu, 40 parts of Borneolum Syntheticums.
4. the external Chinese medicine of prevention according to claim 1 and treatment phlebitis caused by chemotherapeutic medicines is characterized in that being made up of following raw materials in weight portion medicine: 80 parts of charred Radix Sanguisorbae, 30 parts of Fructus Forsythiaes, 60 parts of Radix Et Rhizoma Rhei, 80 parts in catechu, 60 parts of Borneolum Syntheticums.
According to each described prevention of claim 1-4 and the treatment phlebitis caused by chemotherapeutic medicines external Chinese medicine; It is characterized in that this external preparation method of Chinese medicine is that the said crude drug pulverize separately of respectively distinguishing the flavor of is become 200 order medicated powder; According to the weight portion proportioning of each crude drug in the external Chinese prescription powder of getting it filled; Medicated powder is mixed, and modulation evenly makes Chinese medicine powder.
6. the external preparation method of Chinese medicine of each described prevention of claim 1-4 and treatment phlebitis caused by chemotherapeutic medicines; It is characterized in that may further comprise the steps: the said crude drug pulverize separately of respectively distinguishing the flavor of is become 200 order medicated powder; According to the weight portion proportioning of each crude drug in the external Chinese prescription powder of getting it filled; Medicated powder is mixed, and modulation evenly makes Chinese medicine powder.
7. each described external Chinese medicine of claim 1-5 prevents and treats the purposes in the caused phlebitic medicine of chemotherapeutics in preparation.
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| CN2010102724391A CN101926868B (en) | 2010-09-06 | 2010-09-06 | External traditional Chinese medicine for preventing and treating phlebitis caused by chemotherapeutic medicines |
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| CN2010102724391A CN101926868B (en) | 2010-09-06 | 2010-09-06 | External traditional Chinese medicine for preventing and treating phlebitis caused by chemotherapeutic medicines |
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| CN101926868A CN101926868A (en) | 2010-12-29 |
| CN101926868B true CN101926868B (en) | 2012-01-18 |
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| CN103655854B (en) * | 2012-09-18 | 2015-10-07 | 韩立丽 | Treatment venous transfusion causes phlebitic application compress and using method |
| CN103432561B (en) * | 2013-09-11 | 2015-06-24 | 刘春红 | Traditional Chinese medicament for treating phlebitis |
| CN104083592B (en) * | 2014-07-28 | 2017-07-14 | 河南中医学院 | A kind of Externally applied Chinese medicine liquid for treating phlebitis caused by chemotherapeutic medicines |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101607000A (en) * | 2009-02-14 | 2009-12-23 | 房笑丽 | Seven-ingredient pulse-invigorating hot compress patch and prevention and treatment of infusion phlebitis by using same |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101607000A (en) * | 2009-02-14 | 2009-12-23 | 房笑丽 | Seven-ingredient pulse-invigorating hot compress patch and prevention and treatment of infusion phlebitis by using same |
Non-Patent Citations (2)
| Title |
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| 史常青等.长春瑞滨致静脉反应防治方法探讨.《中国实用护理杂志》.2005,第21卷(第5期),第39-40页. * |
| 李佩文.化疗药外漏引起局部损伤的中医治疗.《中日友好医院学报》.2004,第18卷(第1期),第39-41页. * |
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