CN109125464A - A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis - Google Patents
A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis Download PDFInfo
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- CN109125464A CN109125464A CN201811047947.2A CN201811047947A CN109125464A CN 109125464 A CN109125464 A CN 109125464A CN 201811047947 A CN201811047947 A CN 201811047947A CN 109125464 A CN109125464 A CN 109125464A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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Abstract
The present invention relates to a kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis, the active principle of Chinese medicine composition of the invention is made of indigo naturalis, the coptis, radix scutellariae, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis.The Chinese medicine composition can treat phlebitis, the beneficial effect which acts on human body be single dose it is incomparable.The simple production process of the drug is easy to take, is significant in efficacy, is a kind of Chinese medicine composition of ideal treatment phlebitis.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis.
Background technique
Phlebitis is to lead to blood vessel internal membrane damage due to hypertonic drug, smooth muscle spasm, vascellum endometrial hyperplasia, and lumen becomes
Narrow, slow blood flow causes phlebitis.
Clinically using mechanicalness caused by infusion small steel needle, superficial vein retained needle, cannula of deep vein needle, long-time defeated
Caused by the medical fluid for infusing high concentration strong stimulation, there is streak red and swollen heat pain, generation scleroma etc. in various degree in local vein
Vein scorching reaction.This and the material of conduit, the vascular conditions of patient, nurse puncture technique, use pharmaceutical properties, puncture
The activity condition etc. of suffering limb has relationship during the selection at position, indwelling.
" 50% magnesium sulfate solution " local applying hot soaks is clinically routinely used for such phlebitis at present, however due to needing
Magnesium sulfate applying hot soaks gauze is replaced repeatedly, in addition the reasons such as manpower and material resources, often effect is not especially desirable.In addition there are also very much
Hospital, which commonly uses " happiness the Liao Dynasty is appropriate " next part and applies outside, achievees the purpose that local inflammation is promoted to absorb, but needs are according to the phlebitis of patient
The daily massage type of degree is smeared 1-3 times, and massage degree needs that ointment is made to infiltrate through skin degree.
Summary of the invention
The present invention be directed to defects of the existing technology to provide a kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis.
The purpose of the present invention can be achieved through the following technical solutions:
A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis, the effective component of the composition are indigo naturalis, the coptis, radix scutellariae, Huang
Cypress, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis, and formed by the raw material of following weight parts: 1~80 part of indigo naturalis, the coptis 1~80
Part, 1~80 part of radix scutellariae, 1~80 part of Cortex Phellodendri, 1~80 part of raw rhubarb, 1~80 part of radices trichosanthis, 1~80 part of saltcake and rhizoma corydalis 1~
80 parts.
In some preferred technical solutions: indigo naturalis, the coptis, Huang in the External-applicationtraditional traditional Chinese medicinal for treating phlebitis
A kind of reed mentioned in ancient books, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis parts by weight be followed successively by 1~80 part, 1~80 part, 1~80 part, 1~80
Part, 1~50 part, 1~50 part, 1~50 part and 1~30 part.
In some more preferably technical solutions: indigo naturalis in the External-applicationtraditional traditional Chinese medicinal for treating phlebitis, the coptis,
Radix scutellariae, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis parts by weight be followed successively by 30~80 parts, 30~80 parts, 30~80 parts,
30~80 parts, 10~50 parts, 10~50 parts, 10~50 parts and 1~15 part.
In some most preferred technical solutions: indigo naturalis, the coptis, Huang in the External-applicationtraditional traditional Chinese medicinal for treating phlebitis
A kind of reed mentioned in ancient books, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis parts by weight be followed successively by 50 parts, 50 parts, 50 parts, 50 parts, 30 parts, 20
Part, 20 parts and 5 parts.
In the External-applicationtraditional traditional Chinese medicinal for the treatment of phlebitis of the present invention: after the effective component mixing of composition, being added
Clinically-acceptable external application dosage form is made in pharmaceutically acceptable auxiliary material.
Chinese medicine composition described in technical solution of the present invention is as the application in preparation prevention and treatment phlebitis drug.
Fang Zhong:
Indigo naturalis: clearing heat, releasing toxin, removing swelling, cooling blood and hemostasis, the effect of removing obstruction in channels to relieve pain；
The coptis: heat-clearing and damp-drying drug, purging fire for removing toxin；
Radix scutellariae: heat-clearing and damp-drying drug, purging fire for removing toxin；
Cortex Phellodendri: there are heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment；
Raw rhubarb: stagnant, clearing away damp-heat, purging intense heat, cool blood, dissolving stasis and hemostasis, removing toxic substances are attacked；
Radices trichosanthis: clearing heat-fire promotes the production of body fluid to quench thirst, detumescence and apocenosis；
Saltcake: relieving constipation by purgation, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat；
Rhizoma corydalis: promoting qi circulation and relieving pain, promoting blood circulation to remove blood stasis, traumatic injury.
After the definition of " collaboration improves " can be understood as several medicinal material combinations in the present invention, drug effect is relative to exclusive use
When raising；Drug effect is more lasting；Composition generates unexpected effect in new prevention and treatment or healthcare field.
Inventor is found by experiment that composition of the invention has the function for the treatment of phlebitis.These single doses pass through one
After the composition of certainty ratio to human body effect beneficial effect be single dose it is incomparable.
Beneficial effects of the present invention:
The effective component of pharmaceutical composition of the present invention be indigo naturalis, the coptis, radix scutellariae, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and
Rhizoma corydalis, the Chinese medicine composition can be used for treating vein, and the beneficial effect which acts on human body is single dose institute
Incomparable.The simple production process of the drug is easy to take, is significant in efficacy, is a kind of Chinese medicine of ideal treatment vein
Composition.
Specific embodiment
Below with reference to embodiment, the present invention will be further described, and but the scope of the present invention is not limited thereto:
Embodiment 1
A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis is made of the raw material that following weight parts match:
Indigo naturalis 30g, coptis 80g, radix scutellariae 50g, Cortex Phellodendri 60g, raw rhubarb 10g, radices trichosanthis 20g, saltcake 30g, rhizoma corydalis
15g, auxiliary material are vaseline 100g.
Treat the preparation method of the External-applicationtraditional traditional Chinese medicinal of phlebitis the following steps are included:
Indigo naturalis, the coptis, radix scutellariae, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis are claimed according to above-mentioned weight
Weight, is uniformly mixed into mixture, and mixture crushed 200 meshes with pulverizer, vaseline is added, is mixed into lotion.
Embodiment 2
A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis is made of the raw material that following weight parts match:
Indigo naturalis 80g, coptis 30g, radix scutellariae 80g, Cortex Phellodendri 50g, raw rhubarb 50g, radices trichosanthis 50g, saltcake 10g, rhizoma corydalis
10g, auxiliary material are vaseline 100g.
Treat the preparation method of the External-applicationtraditional traditional Chinese medicinal of phlebitis the following steps are included:
Indigo naturalis, the coptis, radix scutellariae, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis are claimed according to above-mentioned weight
Weight, is uniformly mixed into mixture, and mixture crushed 200 meshes with pulverizer, vaseline is added, is mixed into lotion.
Embodiment 3
A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis is made of the raw material that following weight parts match:
Indigo naturalis 50g, coptis 50g, radix scutellariae 50g, Cortex Phellodendri 50g, raw rhubarb 30g, radices trichosanthis 20g, saltcake 20g, rhizoma corydalis 5g,
Auxiliary material is vaseline 100g.
Treat the preparation method of the External-applicationtraditional traditional Chinese medicinal of phlebitis the following steps are included:
Indigo naturalis, the coptis, radix scutellariae, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis are claimed according to above-mentioned weight
Weight, is uniformly mixed into mixture, and mixture crushed 200 meshes with pulverizer, vaseline is added, is mixed into lotion.
Comparative example 1
In addition to lacking indigo naturalis in component, other are the same as embodiment 1.
Comparative example 2
In addition to lacking raw rhubarb and radices trichosanthis in component, other are the same as embodiment 2.
Comparative example 3
In addition to lacking the coptis, saltcake and radices trichosanthis in component, other are the same as embodiment 3.
Pharmacodynamics test statistics:
Medical history information
660 cases merge phlebitis from blood disease indwelling PICC in December, -2017 Jiangsu hospital in January, 2015 and suffer from
Person.
The diagnosis of PICC phlebitis；
(1) there is red, swollen, hot, pain, moving obstacle in central vein catheter wound and arm；
(2) normal without shiver with cold, peripheral hemogram leucocyte with low-heat；
(3) Pi Wengao touches the streak vein of painful.
The judgment criteria of curative effect
The judgment criteria of curative effect is referring to " clinical disease diagnosis is according to the criteria for recovery " and " Chinese medical disease diagnoses curative effect mark
It is quasi- " it formulates.
Clinical cure: clinical symptoms and sign disappear；Central vein catheter wound and arm it is red, it is swollen, hot, pain, activity barrier
Hinder disappearance；
It is effective: central vein catheter wound and arm is red, swollen, hot, pain, moving obstacle degree are substantially reduced.
It is invalid: clinical symptoms without substantially reduced, central vein catheter wound and arm is red, swollen, hot, pain, moving obstacle without
Significant changes person.
Administrated method: paste is applied with affected part, dressing in 6~12 hours 1 time；1 time a day, continuous use 7 days, every time according to trouble
Locate size, the area of application extends 1.5-2.5 centimetres, preferably 2 centimetres by affected part area outward；0.3-0.7 millimeters of thickness,
It is preferred that 0.5 millimeter.
It is divided into treatment group and control group by random digits table, specific as follows:
Treatment group 1:100 blood disease indwelling PICC merges phlebitis patient, and the age 26-65 years old, male or female was sent out with this
Bright paste treats (embodiment 1), cures 86, effective 9, invalid 5 through clinical treatment observation.
Treatment group 2:100 blood disease indwelling PICC merges phlebitis patient, and the age 26-65 years old, male or female was sent out with this
Bright paste treats (embodiment 2), cures 88, effective 7, invalid 5 through clinical treatment observation.
Treatment group 3:100 blood disease indwelling PICC merges phlebitis patient, and the age 26-65 years old, male or female was sent out with this
Bright paste treats (embodiment 3), cures 90, effective 5, invalid 5 through clinical treatment observation.
1:90 blood disease indwelling PICC of control group merge phlebitis patient, and the age 26-65 years old, male or female was sent out with this
Bright paste treats (comparative example 1), cures 60, effective 20, invalid 10 through clinical treatment observation.
2:90 blood disease indwelling PICC of control group merge phlebitis patient, and the age 26-65 years old, male or female was sent out with this
Bright paste treats (comparative example 2), cures 55, effective 22, invalid 13 through clinical treatment observation.
3:90 blood disease indwelling PICC of control group merge phlebitis patient, and the age 26-65 years old, male or female was sent out with this
Bright paste treats (comparative example 3), cures 52, effective 18, invalid 20 through clinical treatment observation.
Control group: 4:90 blood disease indwelling PICC merging phlebitis patients, the age 26-65 years old, male or female, with 50%
Magnesium sulfate dressing treatment cures 30, effective 27, invalid 33 through clinical treatment observation.
Claims (6)
1. a kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis, it is characterised in that: the effective component of the composition is indigo naturalis, Huang
Company, radix scutellariae, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis, and formed by the raw material of following weight parts: 1~80 part of indigo naturalis,
1~80 part of the coptis, 1~80 part of radix scutellariae, 1~80 part of Cortex Phellodendri, 1~80 part of raw rhubarb, 1~80 part of radices trichosanthis, 1~80 part of saltcake and
1~80 part of rhizoma corydalis.
2. the External-applicationtraditional traditional Chinese medicinal for the treatment of phlebitis according to claim 1, it is characterised in that: indigo naturalis, the coptis, Huang
A kind of reed mentioned in ancient books, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis parts by weight be followed successively by 1~80 part, 1~80 part, 1~80 part, 1~80
Part, 1~50 part, 1~50 part, 1~50 part and 1~30 part.
3. the External-applicationtraditional traditional Chinese medicinal for the treatment of phlebitis according to claim 1, it is characterised in that: indigo naturalis, the coptis, Huang
A kind of reed mentioned in ancient books, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis parts by weight be followed successively by 30~80 parts, 30~80 parts, 30~80 parts, 30
~80 parts, 10~50 parts, 10~50 parts, 10~50 parts and 1~15 part.
4. the External-applicationtraditional traditional Chinese medicinal for the treatment of phlebitis according to claim 1, it is characterised in that: indigo naturalis, the coptis, Huang
A kind of reed mentioned in ancient books, Cortex Phellodendri, raw rhubarb, radices trichosanthis, saltcake and rhizoma corydalis parts by weight be followed successively by 50 parts, 50 parts, 50 parts, 50 parts, 30 parts, 20
Part, 20 parts and 5 parts.
5. it is according to claim 1 treatment phlebitis External-applicationtraditional traditional Chinese medicinal, it is characterised in that: composition it is effective at
After dividing mixing, pharmaceutically acceptable auxiliary material is added, clinically-acceptable external application dosage form is made.
6. the described in any item Chinese medicine compositions of claim 1-4 are as the application in preparation prevention and treatment phlebitis drug.
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| CN201811047947.2A CN109125464A (en) | 2018-09-10 | 2018-09-10 | A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111821373A (en) * | 2020-09-01 | 2020-10-27 | 山西丰源药业有限公司 | Traditional Chinese medicine hydrogel external application for treating phlebitis |
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|---|---|---|---|---|
| CN103919896A (en) * | 2014-04-23 | 2014-07-16 | 文成县刀锋科技有限公司 | Externally applied traditional Chinese medicine preparation for treating phlebitis |
| CN106729430A (en) * | 2017-01-17 | 2017-05-31 | 王维 | One kind attacks cancer powder medicine (Zhuyusan) and its application |
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2018
- 2018-09-10 CN CN201811047947.2A patent/CN109125464A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103919896A (en) * | 2014-04-23 | 2014-07-16 | 文成县刀锋科技有限公司 | Externally applied traditional Chinese medicine preparation for treating phlebitis |
| CN106729430A (en) * | 2017-01-17 | 2017-05-31 | 王维 | One kind attacks cancer powder medicine (Zhuyusan) and its application |
Non-Patent Citations (1)
| Title |
|---|
| 李永翠等: "中药外敷预防化疗药物所致静脉炎100例", 《云南中医中药杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111821373A (en) * | 2020-09-01 | 2020-10-27 | 山西丰源药业有限公司 | Traditional Chinese medicine hydrogel external application for treating phlebitis |
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Application publication date: 20190104 |
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