CN106729430A - One kind attacks cancer powder medicine (Zhuyusan) and its application - Google Patents

One kind attacks cancer powder medicine (Zhuyusan) and its application Download PDF

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CN106729430A
CN106729430A CN201710031458.7A CN201710031458A CN106729430A CN 106729430 A CN106729430 A CN 106729430A CN 201710031458 A CN201710031458 A CN 201710031458A CN 106729430 A CN106729430 A CN 106729430A
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zhuyusan
root
powder medicine
saltcake
frankincense
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王维
肖彩芝
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

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Abstract

Cancer powder medicine (Zhuyusan) and its application are attacked the invention discloses one kind, this is attacked cancer powder medicine (Zhuyusan) and is made up of the following raw material according to quality:The 30g of golden cypress 20, the 20g of the root of large-flowered skullcap 10, the 35g of prepared RADIX ET RHIZOMA RHEI 25, the 20g of cape jasmine 10, the 15g of borneol 5, the 15g of frankincense 5, the 20g of root of Chinese trichosanthes 10, the 15g of turmeric 5, the 20g of rhizoma atractylodis 10, the 35g of saltcake 25.External application for curing Drug phlebitis of the present invention, it is evident in efficacy, with bitter cold removing toxic substances, it is eliminating dampness and eliminating phlegm, dispel pathogenic wind and remove dampness, swelling and pain relieving the effects such as, also there is antibacterial, anti-infective, analgesia, spasmolysis, promote microcirculation, regulation local immunity, mitigates that local pain, oedema, exudate be excessive and the effect such as secondary infection.The present invention is when in use, simple to operate, has no side effect, and economical and practical, patient is willing to accept.

Description

One kind attacks cancer powder medicine (Zhuyusan) and its application
Technical field
The present invention relates to pharmaceutical technology field, specifically one kind attacks cancer powder medicine (Zhuyusan) and its application.
Background technology
Phlebitis is the abbreviation of thrombophlebitis.Refer to the acute aseptic inflammation of vein blood vessel, according to diseased region Difference, phlebitis can be divided into superficial phlebitis and deep phlebitis.Etiological:Vein is input into strong and stimulating, high concentration medicine or makes It is more long with the time, damage venous endothelial cell;Superficial veins varicose, hypostasis;Obesity, smoking, wound cause venous endothelial Damage;Bacterium infection etc..Cardinal symptom:Sick lower limb vein is red and swollen, pain, accessible pain sex cords shape runner or beading sample tubercle etc..
The method of current clinical treatment Drug phlebitis is more, and main treatment measures have the soak of medicine, such as use sulphur Sour magnesium local wet dressing.But this ruling by law treats phlebitis because curative effect is low, the course for the treatment of is long, is gradually eliminated by clinic.And in recent years, research Report finds that the effect for the treatment of by Chinese herbs phlebitis is affirmed recently, is that chemotherapy patients release pain, ensure normally entering for chemotherapy Row has played larger effect.Phlebitis belongs to the category of traditional Chinese medicine " vessle-Bi symptom-complex " " muscular rheumatism " " ulcer on the shank " " evil arteries and veins ", often because of damp and hot, cold-dampness Obstruction of meridian, makes to stop in hemostasis, blockage of vessel and occur.Traditional Chinese medicine thinks that phlebitis is to puncture in infusion process to injure local arteries and veins Network hematogenous blockage causes the stagnant resistance of blood stasis, " not general rule bitterly ", and QI-blood circulation is not smooth, and the defeated cloth of body fluid is obstructed, and causes distending pain;In hemostasis Accumulate, accumulate longization heat, then local pyrexia;Train of thought is damaged.
Therefore a kind of Chinese medicine compound prescription external application for curing Drug phlebitis is researched and developed, patient clinical symptom can be improved, improved Quality of life, ensures being normally carried out for chemotherapy.
The content of the invention
It is an object of the invention to provide it is a kind of it is evident in efficacy, have no side effect, low cost attacks cancer powder medicine (Zhuyusan) and its application, To solve the problems, such as to be proposed in above-mentioned background technology.
To achieve the above object, the present invention provides following technical scheme:
One kind attacks cancer powder medicine (Zhuyusan), is made up of the following raw material according to quality:Golden cypress 20-30g, root of large-flowered skullcap 10-20g, prepared RADIX ET RHIZOMA RHEI 25-35g, cape jasmine 10-20g, borneol 5-15g, frankincense 5-15g, root of Chinese trichosanthes 10-20g, turmeric 5-15g, rhizoma atractylodis 10-20g, saltcake 25-35g。
As further scheme of the invention:It is described to attack cancer powder medicine (Zhuyusan), it is made up of the following raw material according to quality:Golden cypress 22-28g, root of large-flowered skullcap 12-18g, prepared RADIX ET RHIZOMA RHEI 28-32g, cape jasmine 12-18g, borneol 8-12g, frankincense 8-12g, root of Chinese trichosanthes 12-18g, ginger Yellow 8-12g, rhizoma atractylodis 12-18g, saltcake 28-32g.
As further scheme of the invention:It is described to attack cancer powder medicine (Zhuyusan), it is made up of the following raw material according to quality:Golden cypress 25g, root of large-flowered skullcap 15g, prepared RADIX ET RHIZOMA RHEI 30g, cape jasmine 15g, borneol 10g, frankincense 10g, root of Chinese trichosanthes 15g, turmeric 10g, rhizoma atractylodis 15g, saltcake 30g。
As further scheme of the invention:It is described to attack cancer powder medicine (Zhuyusan), be by golden cypress, the root of large-flowered skullcap, prepared RADIX ET RHIZOMA RHEI, cape jasmine, borneol, Frankincense, root of Chinese trichosanthes, turmeric, rhizoma atractylodis, saltcake are smashed, and 200 mesh sieves are obtained final product and attack cancer powder medicine (Zhuyusan) excessively.
As further scheme of the invention:Obtained powder boiling water is tuned into pasty state, is divided in gypsum cotton pad, it is thick Degree 0.4-0.5cm, obtains final product.
The application that cancer powder medicine (Zhuyusan) is attacked in treatment phlebitis medicine is prepared.
Effect of each raw material in the present invention:Golden cypress has heat-clearing and damp-drying drug, effect of detoxification sore treatment, for sore swollen toxin, eczema Wet sore.Root of large-flowered skullcap heat-clearing and damp-drying drug, purging intense heat and detonicating, with golden cypress compatibility, treats carbuncle sore tumefacting virus.Prepared RADIX ET RHIZOMA RHEI, purging intense heat and detonicating, for fiery poison sore Ulcer.Cape jasmine heat-clearing, purging intense heat, cool blood.Pyreticosis restlessness of asrhenia type and insomnia is controlled, pathopyretic ulcer is sprained and swollen and ache.Borneol, with heat-clearing dissipates poison, improving eyesight Effect of screen is moved back, aphtha tooth swells, sore carbuncle infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid, red eye, swell pain is cured mainly.Frankincense, blood-activating and qi-promoting analgesic, detumescence and promoting granulation;For the obstruction of qi in the chest It is pained, gastral cavity pain, dysmenorrhoea Amenorrhea, postpartum stasis, abdominal mass stomachache, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore. Root of Chinese trichosanthes clearing heat-fire, promotes the production of body fluid to quench thirst, detumescence and apocenosis;Treatment pyreticosis polydipsia, lung-heat type cough, Heat Diabetes, sore swollen toxin.Turmeric Blood-breaking, promoting the circulation of qi is stimulated the menstrual flow, analgesic;Trusted subordinate's feeling of fullness distending pain is controlled, brachialgia, abdominal mass, women's blood stasis is through closing, the postpartum stasis of blood is stopped stomachache, falls and flutter damage Wound, carbuncle swells.Rhizoma atractylodis, drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight;For damp retention in middle-jiao, abdominal fullness and distention, diarrhea, oedema, tinea pedis impotence is knitted, Arthralgia pain due to rheumatism, anemofrigid cold, yctalopia, eyes dusk is puckery.Saltcake, relieving constipation by purgation, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat;It is stagnant for real heat, The full distending pain of abdomen, dry feces, acute appendicitis swells and ache;Control acute mastitis, hemorrhoid gall outward.
Compared with prior art, the beneficial effects of the invention are as follows:
1. the present invention has feature evident in efficacy.External application for curing Drug phlebitis of the present invention, Clinical practice for many years, be Fruitful Empirical formula.There is now the name patient of our hospital more than 2000 to benefit from it, research display, external application for curing Drug of the present invention Phlebitis curative effect is better than 50% magnesium sulfate dressing.
2. the present invention have bitter cold removing toxic substances, it is eliminating dampness and eliminating phlegm, dispel pathogenic wind and remove dampness, swelling and pain relieving the effects such as.Modern study discovery, this Invention has antibacterial, anti-infective, analgesia, spasmolysis, promotes microcirculation, adjusts local immunity, mitigates local pain, oedema, oozes out Thing is excessive and secondary infection etc. is acted on.
3. the present invention is when in use, simple to operate, has no side effect.By docile after the direct levigation of Chinese medicine at phlebitis, tool The characteristics of having simple to operate.The name patient of clinical observation more than 2000 has no obvious side reaction using the external application present invention.
4. the present invention is economical and practical.Chinese medicine used in the present invention is the general Chinese medicine of in the market, whole auxiliary general more than 20 Yuan, can stick 10-14 days according to position and area is sticked, and economical and practical, patient is willing to accept.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based in the present invention Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, one kind attacks cancer powder medicine (Zhuyusan), is made up of the following raw material according to quality:Golden cypress 20g, the root of large-flowered skullcap 10g, prepared RADIX ET RHIZOMA RHEI 25g, cape jasmine 10g, borneol 5g, frankincense 5g, root of Chinese trichosanthes 10g, turmeric 5g, rhizoma atractylodis 10g, saltcake 25g.
Embodiment 2
In the embodiment of the present invention, one kind attacks cancer powder medicine (Zhuyusan), is made up of the following raw material according to quality:Golden cypress 30g, the root of large-flowered skullcap 20g, prepared RADIX ET RHIZOMA RHEI 35g, cape jasmine 20g, borneol 15g, frankincense 15g, root of Chinese trichosanthes 20g, turmeric 15g, rhizoma atractylodis 20g, saltcake 35g.
Embodiment 3
In the embodiment of the present invention, one kind attacks cancer powder medicine (Zhuyusan), is made up of the following raw material according to quality:Golden cypress 22g, the root of large-flowered skullcap 12g, prepared RADIX ET RHIZOMA RHEI 28g, cape jasmine 12g, borneol 8g, frankincense 8g, root of Chinese trichosanthes 12g, turmeric 8g, rhizoma atractylodis 12g, saltcake 28g.
Embodiment 4
In the embodiment of the present invention, one kind attacks cancer powder medicine (Zhuyusan), is made up of the following raw material according to quality:Golden cypress 28g, the root of large-flowered skullcap 18g, prepared RADIX ET RHIZOMA RHEI 32g, cape jasmine 18g, borneol 12g, frankincense 12g, root of Chinese trichosanthes 18g, turmeric 12g, rhizoma atractylodis 18g, saltcake 32g.
Embodiment 5
In the embodiment of the present invention, one kind attacks cancer powder medicine (Zhuyusan), is made up of the following raw material according to quality:Golden cypress 25g, the root of large-flowered skullcap 15g, prepared RADIX ET RHIZOMA RHEI 30g, cape jasmine 15g, borneol 10g, frankincense 10g, root of Chinese trichosanthes 15g, turmeric 10g, rhizoma atractylodis 15g, saltcake 30g.
Usage and the course for the treatment of:Raw material of the present invention is ground to the powder, 200 mesh sieves is crossed standby.Medicine end boiling water is tuned into pasty state, is divided In in gypsum cotton pad, thickness about 0.5cm, area diameter is more than phlebitis area skin 2cm, order mulching warp layer on ointment Cloth, layer of plastic film, and close fixation with desensitization adhesive plaster.One time a day, application time 4 hours, and the course for the treatment of 10 days can use 2~3 The individual course for the treatment of.
384 phlebitis patients are divided into observation group 252, control group 132.Observation group is controlled using external application of the present invention Treat;Control group uses 50% magnesium sulfate external application for curing.It is 63.49% that result display observation group is efficient, and control group effective percentage is 55.30%, two groups of comparing differences are statistically significant (p < 0.05).The method of external application for curing phlebitis of the present invention is substantially better than 50% magnesium sulfate.The present invention have activate blood circulation and disperse blood clots, clearing heat and detoxicating effect.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be in other specific forms realized.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit requires to be limited rather than described above, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each implementation method is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that for clarity, those skilled in the art should Specification an as entirety, the technical scheme in each embodiment can also be formed into those skilled in the art through appropriately combined May be appreciated other embodiment.

Claims (6)

1. one kind attacks cancer powder medicine (Zhuyusan), it is characterised in that be made up of the following raw material according to quality:Golden cypress 20-30g, root of large-flowered skullcap 10- 20g, prepared RADIX ET RHIZOMA RHEI 25-35g, cape jasmine 10-20g, borneol 5-15g, frankincense 5-15g, root of Chinese trichosanthes 10-20g, turmeric 5-15g, rhizoma atractylodis 10-20g, saltcake 25-35g.
2. it is according to claim 1 to attack cancer powder medicine (Zhuyusan), it is characterised in that to be made up of the following raw material according to quality:Golden cypress 22-28g, root of large-flowered skullcap 12-18g, prepared RADIX ET RHIZOMA RHEI 28-32g, cape jasmine 12-18g, borneol 8-12g, frankincense 8-12g, root of Chinese trichosanthes 12-18g, ginger Yellow 8-12g, rhizoma atractylodis 12-18g, saltcake 28-32g.
3. it is according to claim 1 to attack cancer powder medicine (Zhuyusan), it is characterised in that to be made up of the following raw material according to quality:Golden cypress 25g, root of large-flowered skullcap 15g, prepared RADIX ET RHIZOMA RHEI 30g, cape jasmine 15g, borneol 10g, frankincense 10g, root of Chinese trichosanthes 15g, turmeric 10g, rhizoma atractylodis 15g, saltcake 30g。
4. described attack cancer powder medicine (Zhuyusan) according to claim 1-3 is any, it is characterised in that by golden cypress, the root of large-flowered skullcap, prepared RADIX ET RHIZOMA RHEI, cape jasmine, Borneol, frankincense, root of Chinese trichosanthes, turmeric, rhizoma atractylodis, saltcake are smashed, and 200 mesh sieves are obtained final product and attack cancer powder medicine (Zhuyusan) excessively.
5. it is according to claim 4 to attack cancer powder medicine (Zhuyusan), it is characterised in that obtained powder boiling water is tuned into pasty state, put down Spread out in gypsum cotton pad, thickness 0.4-0.5cm is obtained final product.
6. the application in treating phlebitis medicine is being prepared according to any described cancer powder medicine (Zhuyusan)s of attacking of claim 1-3.
CN201710031458.7A 2017-01-17 2017-01-17 One kind attacks cancer powder medicine (Zhuyusan) and its application Pending CN106729430A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107812091A (en) * 2017-11-22 2018-03-20 北京肿瘤医院 A kind of Chinese medicine preparation for treating phlebitis caused by chemotherapeutics and preparation method thereof
CN109125464A (en) * 2018-09-10 2019-01-04 常州市第三人民医院 A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101129661A (en) * 2007-08-21 2008-02-27 王军 Powder for easing tendon and activating collateral flow
CN101214290A (en) * 2008-01-18 2008-07-09 深圳市福田区中医院 Powder for dispersing blood stasis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101129661A (en) * 2007-08-21 2008-02-27 王军 Powder for easing tendon and activating collateral flow
CN101214290A (en) * 2008-01-18 2008-07-09 深圳市福田区中医院 Powder for dispersing blood stasis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
华金荣: "静滴β-七叶皂甙钠致静脉炎的中药外敷治疗", 《中国民间疗法》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107812091A (en) * 2017-11-22 2018-03-20 北京肿瘤医院 A kind of Chinese medicine preparation for treating phlebitis caused by chemotherapeutics and preparation method thereof
CN107812091B (en) * 2017-11-22 2020-08-25 北京肿瘤医院 Traditional Chinese medicine preparation for treating phlebitis caused by chemotherapy drugs and preparation method thereof
CN109125464A (en) * 2018-09-10 2019-01-04 常州市第三人民医院 A kind of External-applicationtraditional traditional Chinese medicinal for treating phlebitis

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