CN104080472A - 用于在抑制或预防肿瘤生长中使用的骨桥蛋白变体和包含这类骨桥蛋白变体的组合物 - Google Patents

用于在抑制或预防肿瘤生长中使用的骨桥蛋白变体和包含这类骨桥蛋白变体的组合物 Download PDF

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Publication number
CN104080472A
CN104080472A CN201280068303.6A CN201280068303A CN104080472A CN 104080472 A CN104080472 A CN 104080472A CN 201280068303 A CN201280068303 A CN 201280068303A CN 104080472 A CN104080472 A CN 104080472A
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CN
China
Prior art keywords
opn
seq
variant
active
molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280068303.6A
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English (en)
Chinese (zh)
Inventor
苏珊·R·里特林
彼得·朗堡·魏谢
安雅·塞丽娜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forsyth Children's Stomatological Hospital (under Name Of Forsyth Institute)
Arla Foods AMBA
Original Assignee
Forsyth Children's Stomatological Hospital (under Name Of Forsyth Institute)
Arla Foods AMBA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forsyth Children's Stomatological Hospital (under Name Of Forsyth Institute), Arla Foods AMBA filed Critical Forsyth Children's Stomatological Hospital (under Name Of Forsyth Institute)
Publication of CN104080472A publication Critical patent/CN104080472A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201280068303.6A 2011-12-07 2012-12-07 用于在抑制或预防肿瘤生长中使用的骨桥蛋白变体和包含这类骨桥蛋白变体的组合物 Pending CN104080472A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161567899P 2011-12-07 2011-12-07
US61/567,899 2011-12-07
US201261673912P 2012-07-20 2012-07-20
EP12177329.5 2012-07-20
EP12177329 2012-07-20
US61/673,912 2012-07-20
PCT/US2012/068628 WO2013086459A1 (en) 2011-12-07 2012-12-07 Osteopontin variants for use in suppression or prevention of tumor growth and compositions containing such osteopontin variants

Publications (1)

Publication Number Publication Date
CN104080472A true CN104080472A (zh) 2014-10-01

Family

ID=48574961

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280068303.6A Pending CN104080472A (zh) 2011-12-07 2012-12-07 用于在抑制或预防肿瘤生长中使用的骨桥蛋白变体和包含这类骨桥蛋白变体的组合物

Country Status (12)

Country Link
US (1) US20150344534A1 (https=)
EP (1) EP2788015A1 (https=)
JP (1) JP2015500836A (https=)
KR (1) KR20140104474A (https=)
CN (1) CN104080472A (https=)
AR (1) AR089136A1 (https=)
AU (1) AU2012347468A1 (https=)
BR (1) BR112014013565A2 (https=)
CA (1) CA2858379A1 (https=)
EA (1) EA201491010A1 (https=)
WO (1) WO2013086459A1 (https=)
ZA (1) ZA201404920B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2656474T3 (es) 2013-07-05 2018-02-27 Arla Foods Amba Osteopontina láctea de origen mamífero para potenciar la capacidad de respuesta inmune
EP4326758A4 (en) * 2021-04-20 2025-03-19 University of Cincinnati A vaccine adjuvant for infectious diseases

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000063241A2 (en) * 1999-04-15 2000-10-26 Children's Medical Center Corporation Methods and compositions for modulating an immune response

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888552A (en) * 1988-04-29 1999-03-30 Immunotec Research Corporation Ltd. Anti-cancer therapeutic compositions containing whey protein concentrate
IL106576A (en) * 1992-08-13 2000-08-13 Immunotec Res Corp Ltd Anti-cancer therapeutic compositions for prophylaxis or for treatment of cancer
US7259243B2 (en) * 2000-01-07 2007-08-21 Arla Foods Amba Process for isolation of osteopontin from milk
NZ507335A (en) * 2000-10-05 2004-10-29 New Zealand Dairy Board Bone health compositions derived from milk comprising an acidic protein fraction but that does not contain CGMP
JP4509114B2 (ja) * 2003-09-18 2010-07-21 アルラ・フーズ・エイ・エム・ビィ・エイ 幼児用調製乳
SM200600031B (it) * 2006-10-06 2009-05-11 Gianluca Mech Integratore alimentare con attivatore proteico
ES2538362T3 (es) * 2007-10-16 2015-06-19 Ventana Medical Systems, Inc. Clasificación, estadificación y pronóstico del cáncer mediante el uso de osteopontina-C

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000063241A2 (en) * 1999-04-15 2000-10-26 Children's Medical Center Corporation Methods and compositions for modulating an immune response

Also Published As

Publication number Publication date
EA201491010A1 (ru) 2015-01-30
AR089136A1 (es) 2014-07-30
EP2788015A1 (en) 2014-10-15
WO2013086459A1 (en) 2013-06-13
KR20140104474A (ko) 2014-08-28
AU2012347468A1 (en) 2014-06-26
BR112014013565A2 (pt) 2019-09-24
ZA201404920B (en) 2015-12-23
US20150344534A1 (en) 2015-12-03
CA2858379A1 (en) 2013-06-13
JP2015500836A (ja) 2015-01-08

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Application publication date: 20141001