CN104072468A - Proanthocyanidin extraction process from camellia seed hull - Google Patents

Proanthocyanidin extraction process from camellia seed hull Download PDF

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Publication number
CN104072468A
CN104072468A CN201310099242.6A CN201310099242A CN104072468A CN 104072468 A CN104072468 A CN 104072468A CN 201310099242 A CN201310099242 A CN 201310099242A CN 104072468 A CN104072468 A CN 104072468A
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CN
China
Prior art keywords
extraction
proanthocyanidin
pycnogenols
extraction process
camellia seed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310099242.6A
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Chinese (zh)
Inventor
易大发
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YICHUN YUANBOSHAN TEA OIL SCIENCE & TECHNOLOGY AGRICULTURAL DEVELOPMENT Co Ltd
Original Assignee
YICHUN YUANBOSHAN TEA OIL SCIENCE & TECHNOLOGY AGRICULTURAL DEVELOPMENT Co Ltd
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Application filed by YICHUN YUANBOSHAN TEA OIL SCIENCE & TECHNOLOGY AGRICULTURAL DEVELOPMENT Co Ltd filed Critical YICHUN YUANBOSHAN TEA OIL SCIENCE & TECHNOLOGY AGRICULTURAL DEVELOPMENT Co Ltd
Priority to CN201310099242.6A priority Critical patent/CN104072468A/en
Publication of CN104072468A publication Critical patent/CN104072468A/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Extraction Or Liquid Replacement (AREA)

Abstract

The invention relates to the technical field of medicine processing and discloses a proanthocyanidin extraction process from camellia seed hull. The extraction process includes: 1) a step of extracting proanthocyanidin in the camellia seed hull for 10-30 min by adoption of a supercritical CO2 fluid extraction method; 2) a step of simultaneously filtering and adsorbing the proanthocyanidin for 10-20 min by a flocculation clarification technology and a resin adsorption separation technology; and 3) drying for 20-30 min through a spraying drying process, and therefore the proanthocyanidin with a purity of 94-96% and an extraction yield of 1-3% can be obtained. The extraction process has characteristics of high extraction speed of the proanthocyanidin from the camellia seed hull, high efficiency and less energy consumption. Operation parameters can be controlled easily, thus effectively guaranteeing the stable product quality.

Description

The extraction process of pycnogenols in tea seed shell
Technical field:
The present invention relates to a kind of medicine processing technique field, be specifically related to a kind of supercritical CO 2extraction-flocculence extracts the extraction process of pycnogenols in purifying tea seed shell.
Background technology:
From natural animal-plant, extract effective ingredient, significant to improving resource utilization and social production standard of living.The oil tea resource of China is very abundant, and according to statistics, approximately there is oil tea fifty-five million mu in the whole nation, and 1,500,000 tons of annual produce oils refine after tea oil the tea seed shell that brings more than 1,000 ten thousand tons.If these a large amount of remaining tea seed shells can be used by light industry biotechnology, huge economic benefit will be produced.Research shows to have the pycnogenols that value of exploiting and utilizing is high, the market requirement is vigorous in the composition of tea seed shell.
Pycnogenols is a kind of Vitamin P complex that has special molecular structure, there is very strong anti-oxidant and removing free radical activity, there is cancer-resisting, prevention and cure of cardiovascular disease, hyperglycemia, radioprotective, immunomodulatory, improves the multiple efficacies such as microcirculation in human body, along with going deep into of research, its huge development and application values more and more obtains people's attention, has staple market prospect.Although the using value of pycnogenols is high, have wide range of applications, due to crude substance complicated component, content is generally fewer, so the quality of extraction and separation technology is the key that obtains pycnogenols.
There is obvious defect in traditional pickling process, reflux extraction, loaded down with trivial details, the consuming time length of organic solvent, processing step as inflammable in a large amount of uses, easily causes loss and the organic solvent residual problem of thermo-sensitivity composition degraded and volatile component.
Summary of the invention:
The extraction process that the object of this invention is to provide pycnogenols in a kind of tea seed shell, it can be fast to the pycnogenols rate of extraction in oil tea shell, efficiency is high, less energy consumption, and operating parameters is easy to control, and can effectively guarantee constant product quality.
In order to solve the existing problem of background technology, the present invention adopts following technical scheme: its extraction process is: one, adopt supercritical CO 2fluid extraction method was by the pycnogenols extraction in oil tea shell 10～30 minutes; Two, by flocculate and clarify technology and resin absorption isolation technique, pycnogenols is filtered and adsorb 10～20 minutes simultaneously; Three, by drying process with atomizing, be dried, be 20～30 minutes time of drying, and can obtain extraction yield is 1～3%, the pycnogenols that purity is 94%～96%.
The present invention adopts supercritical CO 2fluid extraction method, utilizes the dissolving power of supercutical fluid and the relation of its density, utilizes pressure and temperature to carry out the impact of supercutical fluid dissolving power.Under supercritical state, supercutical fluid is contacted with material to be separated, it is extracted the composition of polarity size, boiling point height and molecular size range selectively successively.
The present invention is fast to the pycnogenols rate of extraction in oil tea shell, efficiency is high, less energy consumption, and operating parameters is easy to control, and can effectively guarantee constant product quality.The open defect of having avoided pickling process, reflux extraction to exist, organic solvent, processing step as inflammable in a large amount of uses loaded down with trivial details, consuming time length, easily causes loss and the organic solvent residual problem of the degraded of thermo-sensitivity composition and volatile component.
Embodiment:
This embodiment adopts following technical scheme: its extraction process is: one, adopt supercritical CO 2fluid extraction method was by the pycnogenols extraction in oil tea shell 10～30 minutes; Two, by flocculate and clarify technology and resin absorption isolation technique, pycnogenols is filtered and adsorb 10～20 minutes simultaneously; Three, by drying process with atomizing, be dried, be 20～30 minutes time of drying, and can obtain extraction yield is 1～3%, the pycnogenols that purity is 94%～96%.
This embodiment adopts supercritical CO 2fluid extraction method, utilizes the dissolving power of supercutical fluid and the relation of its density, utilizes pressure and temperature to carry out the impact of supercutical fluid dissolving power.Under supercritical state, supercutical fluid is contacted with material to be separated, it is extracted the composition of polarity size, boiling point height and molecular size range selectively successively.
This embodiment is fast to the pycnogenols rate of extraction in oil tea shell, efficiency is high, less energy consumption, and operating parameters is easy to control, and can effectively guarantee constant product quality.The open defect of having avoided pickling process, reflux extraction to exist, organic solvent, processing step as inflammable in a large amount of uses loaded down with trivial details, consuming time length, easily causes loss and the organic solvent residual problem of the degraded of thermo-sensitivity composition and volatile component.

Claims (1)

1. the extraction process of pycnogenols in tea seed shell, is characterized in that its extraction process is: one, adopt supercritical CO 2fluid extraction method was by the pycnogenols extraction in oil tea shell 10～30 minutes; Two, by flocculate and clarify technology and resin absorption isolation technique, pycnogenols is filtered and adsorb 10～20 minutes simultaneously; Three, by drying process with atomizing, be dried, be 20～30 minutes time of drying, and can obtain extraction yield is 1～3%, the pycnogenols that purity is 94%～96%.
CN201310099242.6A 2013-03-26 2013-03-26 Proanthocyanidin extraction process from camellia seed hull Pending CN104072468A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310099242.6A CN104072468A (en) 2013-03-26 2013-03-26 Proanthocyanidin extraction process from camellia seed hull

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310099242.6A CN104072468A (en) 2013-03-26 2013-03-26 Proanthocyanidin extraction process from camellia seed hull

Publications (1)

Publication Number Publication Date
CN104072468A true CN104072468A (en) 2014-10-01

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CN201310099242.6A Pending CN104072468A (en) 2013-03-26 2013-03-26 Proanthocyanidin extraction process from camellia seed hull

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CN (1) CN104072468A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104447941A (en) * 2014-12-19 2015-03-25 江西省科学院应用化学研究所 Method for simultaneous extraction of oligomeric proanthocyanidins and tea saponin from camellia oleifera shells
CN105853298A (en) * 2016-05-24 2016-08-17 南宁圣特生物科技有限公司 Preparation method of natural camellia seed shampoo
CN112522341A (en) * 2020-12-30 2021-03-19 江西神州通油茶科技有限公司 Co-production method for extracting xylo-oligosaccharide and procyanidine from camellia oleifera shells

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1749253A (en) * 2005-07-18 2006-03-22 天津大学 Process for extracting proanthocyanidin from grape seed by super critical carbon dioxide
CN101845035A (en) * 2009-03-24 2010-09-29 上海医药工业研究院 Method for extracting oligomeric proanthocyanidins
CN102210786A (en) * 2011-06-08 2011-10-12 中国林业科学研究院林产化学工业研究所 Method for extracting natural antioxidant from shells of camellia oleifera
CN102532086A (en) * 2012-01-12 2012-07-04 北京林业大学 Method for extracting proanthocyanidins from dahurian larch bark

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1749253A (en) * 2005-07-18 2006-03-22 天津大学 Process for extracting proanthocyanidin from grape seed by super critical carbon dioxide
CN101845035A (en) * 2009-03-24 2010-09-29 上海医药工业研究院 Method for extracting oligomeric proanthocyanidins
CN102210786A (en) * 2011-06-08 2011-10-12 中国林业科学研究院林产化学工业研究所 Method for extracting natural antioxidant from shells of camellia oleifera
CN102532086A (en) * 2012-01-12 2012-07-04 北京林业大学 Method for extracting proanthocyanidins from dahurian larch bark

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
秦菲 等.: "原花青素提取方法的研究进展", 《北京联合大学学报( 自然科学版)》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104447941A (en) * 2014-12-19 2015-03-25 江西省科学院应用化学研究所 Method for simultaneous extraction of oligomeric proanthocyanidins and tea saponin from camellia oleifera shells
CN104447941B (en) * 2014-12-19 2016-05-25 江西省科学院应用化学研究所 A kind of synchronous method of extracting of glucosidase procyanidins and Tea Saponin in oil-tea camellia husks
CN105853298A (en) * 2016-05-24 2016-08-17 南宁圣特生物科技有限公司 Preparation method of natural camellia seed shampoo
CN105853298B (en) * 2016-05-24 2019-01-01 南宁圣特生物科技有限公司 A kind of preparation method of natural camellia seed hair shampoo article
CN112522341A (en) * 2020-12-30 2021-03-19 江西神州通油茶科技有限公司 Co-production method for extracting xylo-oligosaccharide and procyanidine from camellia oleifera shells

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Application publication date: 20141001