CN104068395B - The aloe Momordica grosvenori compound capsule that a kind of antioxidation is strong - Google Patents
The aloe Momordica grosvenori compound capsule that a kind of antioxidation is strong Download PDFInfo
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- CN104068395B CN104068395B CN201410249190.0A CN201410249190A CN104068395B CN 104068395 B CN104068395 B CN 104068395B CN 201410249190 A CN201410249190 A CN 201410249190A CN 104068395 B CN104068395 B CN 104068395B
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- 241001116389 Aloe Species 0.000 title claims abstract description 39
- 235000011399 aloe vera Nutrition 0.000 title claims abstract description 39
- 239000002775 capsule Substances 0.000 title claims abstract description 21
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 title claims abstract description 19
- 230000003064 anti-oxidating effect Effects 0.000 title claims abstract description 13
- 150000001875 compounds Chemical class 0.000 title claims abstract description 10
- 241001409321 Siraitia grosvenorii Species 0.000 title claims abstract 3
- 239000000843 powder Substances 0.000 claims abstract description 29
- 239000003086 colorant Substances 0.000 claims abstract description 23
- GHBNZZJYBXQAHG-KUVSNLSMSA-N (2r,3r,4s,5s,6r)-2-[[(2r,3s,4s,5r,6r)-6-[[(3s,8s,9r,10r,11r,13r,14s,17r)-17-[(2r,5r)-5-[(2s,3r,4s,5s,6r)-4,5-dihydroxy-3-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@H](CC[C@@H](C)[C@@H]1[C@]2(C[C@@H](O)[C@@]3(C)[C@H]4C(C([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]6[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O6)O)O5)O)CC4)(C)C)=CC[C@H]3[C@]2(C)CC1)C)C(C)(C)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GHBNZZJYBXQAHG-KUVSNLSMSA-N 0.000 claims abstract description 16
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- 239000008120 corn starch Substances 0.000 claims abstract description 11
- 229940099112 cornstarch Drugs 0.000 claims abstract description 11
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 22
- 239000011248 coating agent Substances 0.000 claims description 14
- 238000000576 coating method Methods 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 14
- 239000002245 particle Substances 0.000 claims description 13
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- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 7
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- 238000003756 stirring Methods 0.000 claims description 4
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- 239000000243 solution Substances 0.000 description 11
- 230000000694 effects Effects 0.000 description 8
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 description 8
- 229940006091 aloe polysaccharide Drugs 0.000 description 6
- 238000006701 autoxidation reaction Methods 0.000 description 4
- 235000013399 edible fruits Nutrition 0.000 description 4
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- 238000012360 testing method Methods 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 229930182478 glucoside Natural products 0.000 description 3
- 150000008131 glucosides Chemical class 0.000 description 3
- 238000005469 granulation Methods 0.000 description 3
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- 230000036039 immunity Effects 0.000 description 3
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- 238000004519 manufacturing process Methods 0.000 description 3
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
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- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010013911 Dysgeusia Diseases 0.000 description 1
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- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- -1 aloe polysaccharide Chemical class 0.000 description 1
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
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- 239000002131 composite material Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000007888 film coating Substances 0.000 description 1
- 238000009501 film coating Methods 0.000 description 1
- 229930182486 flavonoid glycoside Natural products 0.000 description 1
- 150000007955 flavonoid glycosides Chemical class 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 238000012417 linear regression Methods 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000002366 mineral element Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
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- 230000033764 rhythmic process Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
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- 235000019154 vitamin C Nutrition 0.000 description 1
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- 235000020985 whole grains Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses the aloe Momordica grosvenori compound capsule that a kind of antioxidation is strong, adopt following proportioning, in butt % by weight: primary colors aloe leaf freeze dried powder and Fructus Monordicae extract summation 18-27, wherein the ratio of mogroside V and O-acetyl content is 4:1; Cornstarch 40-50; Maltodextrin 20-25; Microcrystalline cellulose 10-15. In finished product, functional component content is: in every 100g product, the ratio of mogroside V and O-acetyl content is 4:1, and O-acetyl group is greater than 1000mg. The weight of capsule is every 0.3g. Positive usual amounts is every day 2-3 time, 1-2 grain at every turn. In this product, primary colors aloe leaf freeze dried powder and Fructus Monordicae extract are supported mutually in this formula, play synergistic effect, have improved the oxidation resistance of product. Proportioning is simple, easy to use, and sample is produced as a trial.
Description
Present patent application is enjoyed priority, and priority patent name is: a kind of aloe Momordica grosvenori compound capsule with antioxidation,
Application number is: 201310304981.4 applyings date were: 2013.07.19.
Technical field
The present invention relates to field of health care food, especially a kind of aloe Momordica grosvenori compound capsule.
Background technology
Now, environmental pollution increasingly sharpens, and adds rhythm of life quickening, and life stress strengthens, and inferior health appears in a lot of people, and aging appears in immunity degradation in advance, and especially white collar women more needs reasonable maintaining. Maintain antioxidant level suitable in human body and free radical scavenger level and can extend and recognize the life-span, delay senility. Need to have anti-oxidant, to strengthen immunity health food, this properties of product gentleness, does not have toxic and side effect to human body, and taking convenience, to remain healthy and beautiful.
Aloe contains the functional components such as anthraquinone analog compound, aloe polysaccharide, amino acid, organic acid, vitamin, mineral matter, enzyme, can be used for food, medicine, cosmetics, there is raising immunity, fat-reducing, the health-care efficacies such as beauty treatment, also have clearing away heat and loosing the bowels, invigorating spleen and reinforcing stomach, improve a poor appetite, the antibacterial antitumor effect that waits. Light industry standard QB/T2489-2007 has specified production technology and the quality index thereof of primary colors aloe leaf freeze dried powder, has wherein specified aloe polysaccharide content, in O-acetyl content, has retained the active component of aloe. Zhang Yumin, Zhong Xiguang discloses the research of a kind of aloe (particle) capsules preparation technique in traditional Chinese medicine Leader, Hunan 2003,9 (9): 56.
Momordica grosvenori is Curcurbitaceae herbaceous perennial vine plant, is the first batch of medicine-food two-purpose rare traditional Chinese medicine of announcing of the Ministry of Public Health, is described as " angle fruit " by people. Momordica grosvenori nutritive value is very high, and containing Momordica grosvenori glucoside, wherein mogroside V is the main component of Momordica grosvenori dry fruit, accounts for 0.5% of dry fruit. Contain in addition glucose, fructose, polysaccharide, protein, amino acid, flavonoid glycosides, vitamin C and multiple mineral element, there is taste sweet cool in nature, return lung, large intestine channel, moisten the lung and relieve the cough, the effect promoting the production of body fluid to quench thirst, be applicable to lung heat or xeropulmonary cough, it is thirsty etc. that pertussis and hot summer weather are hindered Tianjin, the effect relaxing bowel in addition in addition. Momordica grosvenori deep processing is mainly to extract Momordica grosvenori glucoside. Chinese invention patent application publication number is CN101007042A, and name is called the Fructus Monordicae extract preparation method of a kind of decolouring, debitterize, discloses a kind of decolouring, debitterize, containing the method for preparing extractive of Momordica grosvenori glucoside.
Baidupedia (http://baike.baidu.com/view/6064355.htm fr=wordsearch) discloses a kind of aloe Momordica grosvenori fruit congee, and raw material is 150 grams, rice, aloe, and each 15 grams of Momordica grosvenori, effect is the happy look of preserving youthful looks, moistening lung for removing phlegm.
Summary of the invention
Technical problem to be solved by this invention is to provide the aloe Momordica grosvenori compound capsule that a kind of antioxidation is strong, and this capsule defines ratio and the consumption of mogroside V and O-acetyl group, to stomach action temperature and, there is various nutrients.
Technical scheme of the present invention is: the aloe Momordica grosvenori compound capsule that a kind of antioxidation is strong, employing meets the primary colors aloe leaf freeze dried powder that light industry standard QB/T2489-2007 specifies and the Fructus Monordicae extract that is CN101007042A by Chinese invention patent application publication number is primary raw material, add cornstarch, maltodextrin, the auxiliary materials such as microcrystalline cellulose; Through pulverizing, sieve, mix, granulation, dressing, filling, aluminum-plastic packaged, make finished product.
The proportioning of aloe Momordica grosvenori compound capsule is, by butt % by weight,
Primary colors aloe leaf freeze dried powder and Fructus Monordicae extract summation 18-27, wherein the ratio of mogroside V and O-acetyl content is 4:1;
Cornstarch 40-50;
Maltodextrin 20-25;
Microcrystalline cellulose 10-15;
Dressing adopts 2.0% hydroxypropyl methylcellulose (HPMC), and the ethanol of coating solution employing 60% is made solvent, and being made into concentration is 6.0%-8.0% coating solution.
In finished product, functional component content is: in every 100g product, and mogroside V content: O-acetyl content is 4:1, and O-acetyl content is greater than 1000mg.
The weight of capsule is every 0.3g. Positive usual amounts is every day 2-3 time, 1-2 grain at every turn.
First each supplementary material is pulverized, crossed 200 orders and sieve to 300 objects, then adopt V mixer to mix; 95% ethanol softwood processed is selected in granulation, and vibrating sieving machine is granulated, dressing, then at 35-40 DEG C of drying under reduced pressure immediately, further to remove ethanol and moisture, dry after material moisture be controlled at below 3.0%. Then be filled to the hard shell capsules of 0.3g by 1# capsule shells.
The present invention, under the prerequisite of maintenance Fructus Monordicae extract and the basic ratio of primary colors aloe leaf freeze dried powder, can also make other peroral dosage forms, such as tablet, and granule.
The present invention has following advantages and characteristic:
1, quality better. The Fructus Monordicae extract adopting is a kind of decolouring, debitterize, and mogroside V content is more than 50% extract, and color and luster is good, good stability; The primary colors aloe leaf freeze dried powder adopting is also concentrated by normal temperature NF membrane, and the dry powder that freeze drying processing obtains, contains aloe acetylated polysaccharide, amino acid, organic acid, vitamin, mineral matter and other components.
2, antioxidation is strong. Utilize pyrogallol Autoxidation Method to measure product to suppressing pyrogallol autoxidation ability. Be to survey live system with the pyrogallol of 0.1mM, at 50mM, under the Tris-HCl buffer solution of pH=8.2, measure the ultraviolet absorptivity (measuring once for every 30 seconds) of 325nm in 4min, draw linear graph, try to achieve the slope of straight line after linear regression, to add gained straight slope and pyrogallol autoxidation straight slope after primary colors aloe leaf freeze dried powder and Fructus Monordicae extract to compare, determine mogroside V in Fructus Monordicae extract: the relative oxidation resistance of aloe polysaccharide content different proportion in primary colors aloe leaf freeze dried powder. Experimental data shows, mogroside V in Fructus Monordicae extract: when the ratio of aloe polysaccharide content is 4:1 in primary colors aloe leaf freeze dried powder, effect is best, than other ratios, or use separately primary colors aloe leaf freeze dried powder, or the effect of Fructus Monordicae extract also will get well, in Fructus Monordicae extract, in mogroside V and primary colors aloe leaf freeze dried powder, aloe polysaccharide is in the time that ratio is 4:1, and antioxidation is supported mutually, play synergistic effect, oxidation resistance increases suddenly. Below experimental data:
Be 1:1 by mogroside V and aloe polysaccharide (O-acetyl group) ratio setting respectively; 2:1; 4:1,6:1, carries out antioxidation in vitro test, determines the main ingredient composition in aloe Momordica grosvenori capsule, does three groups of parallel laboratory tests, and experimental result is in table 1. Wherein anti-oxidant pipe 1 ratio is 1:1, and anti-oxidant pipe 2 is 2:1, and anti-oxidant pipe 3 is 4:1, and anti-oxidant pipe 4 is 6:1.
Table 1 antioxidation in vitro test data
As shown in Table 1, the anti-oxidant speed of each anti-oxidant pipe is less than autoxidation speed, and anti-oxidant pipe has antioxidation activity, and the less expression oxidation resistance of numerical value of anti-oxidant speed is stronger. The relative oxidation rate value that three experimental results all show anti-oxidant pipe 3 is little, illustrates in the composite oxidation resistance of this ratio the strongest. That is to say that Antioxidation in vitro effect is best in the time that the ratio of mogroside V and O-acetyl group is classified 4:1 as.
3, proportioning is simple, easy to use, adopts granulating coated technology, long shelf-life, and sample is produced as a trial. Be applicable to industrialized production.
Detailed description of the invention
The following stated example understands the present invention in detail. In example, unless otherwise indicated, all umbers and percentage are all by weight.
Embodiment 1
1, by satisfactory Fructus Monordicae extract, primary colors aloe leaf freeze dried powder, pulverize respectively with airslide disintegrating mill, cross 200 mesh sieves, obtain qualified Fructus Monordicae extract and primary colors aloe leaf freeze dried powder, detection level, for subsequent use; Cornstarch, maltodextrin, microcrystalline cellulose is pulverized with Universalpulverizer respectively, crosses 200 mesh sieves, for subsequent use.
2, take the cornstarch 5.0kg crushing, Fructus Monordicae extract 0.8kg, primary colors aloe leaf freeze dried powder 1.0kg, maltodextrin 2.0kg, microcrystalline cellulose 1.2kg. Drop into successively in V mixer, fully mix, obtain 10kg mixture.
3, by 95% ethanol softwood processed for mixture, vibratory sieve is granulated.
4, dressing. Take hydroxypropyl methylcellulose (HPMC) 200g, be made into 8% coating solution with 60% ethanol, dressing control dressing kettle temperature is at 35-40 DEG C, controls turn at 30-35/min of rotating speed, evenly sprays people's coating solution with high-pressure spray gun, and constantly stirs particle. Until coating solution bag is complete. Take out, the dry 2h of decompression (not heating), obtains qualified particle.
5, qualified particle is filled to the hard shell capsules of every of 0.3g at capsule filling machine by 1# capsule shells, polishing, then makes aluminium-plastic panel, and mounted box, makes finished product. Detect this finished product: wherein mogroside V content is 4000mg/100g, O-acetyl content is 1000mg/100g, and after testing, the relatively anti-oxidant speed of this product is 0.8112.
Embodiment 2
1, by satisfactory Fructus Monordicae extract, primary colors aloe leaf freeze dried powder, pulverizes respectively with airslide disintegrating mill, crosses 300 mesh sieves, obtains qualified Fructus Monordicae extract powder and primary colors aloe leaf freeze dried powder, and detection level is for subsequent use; Cornstarch, maltodextrin, microcrystalline cellulose is pulverized with Universalpulverizer respectively, crosses 300 mesh sieves, for subsequent use.
2, take the cornstarch 45kg crushing, Fructus Monordicae extract powder 10kg, primary colors aloe leaf freeze dried powder 12kg, maltodextrin 20kg, microcrystalline cellulose 13kg. Drop into successively in V mixer, fully mix, obtain mixture 100kg.
3, by 95% ethanol softwood processed for mixture, vibratory sieve is granulated.
4, dressing. Take hydroxypropyl methylcellulose 2kg, be made into 6% coating solution with 60% ethanol, dressing control dressing kettle temperature is at 35-40 DEG C, controls turn at 30-35/min of rotating speed, evenly sprays people's coating solution with high-pressure spray gun, and constantly stirs particle. Until coating solution bag is complete. Take out, drying under reduced pressure 2h, obtains qualified particle.
5, qualified particle is filled to the hard shell capsules of every of 0.3g at capsule filling machine by 1# capsule shells, polishing, then makes aluminium-plastic panel, and mounted box, makes finished product. In this finished product, mogroside V content is 6000mg/100g, and O-acetyl content is 1500mg/100g, and after testing, the relatively anti-oxidant speed of this product is 0.8058.
Embodiment 3
1, by satisfactory Fructus Monordicae extract, primary colors aloe leaf freeze dried powder, pulverizes respectively with airslide disintegrating mill, crosses 200 mesh sieves, obtains qualified Fructus Monordicae extract powder and primary colors aloe leaf freeze dried powder, and detection level is for subsequent use; Cornstarch, maltodextrin, microcrystalline cellulose is pulverized with Universalpulverizer respectively, crosses 200 mesh sieves, for subsequent use.
2, take the cornstarch 4.0kg crushing, Fructus Monordicae extract powder 1.2kg, primary colors aloe leaf freeze dried powder 1.5kg, maltodextrin 2.3kg, microcrystalline cellulose 1.0kg. Drop into successively in V mixer, fully mix, obtain mixture.
3, by 95% ethanol softwood processed for mixture, oscillating granulation, whole grain, drying under reduced pressure, the moisture of particle is 2.8%, obtains qualified particle.
4, qualified particle is pressed into the tablet that every is 0.3g with tablet press machine;
5, tablet is adopted to film coating: take hydroxypropyl methylcellulose 0.2kg, be made into 7% coating solution with 60% ethanol, dressing control dressing kettle temperature, at 35-40 DEG C, is controlled turn at 30-35/min of rotating speed, evenly spray people's coating solution with high-pressure spray gun, and constantly stir. Until coating solution bag is complete. Take out, drying under reduced pressure 2h, obtains qualified tablet.
6, make aluminium-plastic panel, mounted box, makes finished product; Or directly pack plastic bottle into, get product. Mogroside V content 5200mg/100g in this finished product, O-acetyl content is 1300mg/100g.
Claims (1)
1. the aloe Momordica grosvenori compound capsule that antioxidation is strong, is characterized in that:
1) by Fructus Monordicae extract, primary colors aloe leaf freeze dried powder, pulverizes respectively with airslide disintegrating mill, crosses 300 mesh sieves, and detection level is for subsequent use; Cornstarch, maltodextrin, microcrystalline cellulose is pulverized with Universalpulverizer respectively, crosses 300 mesh sieves, for subsequent use;
2) take the cornstarch 45kg crushing, Fructus Monordicae extract powder 10kg, primary colors aloe leaf freeze dried powder 12kg, maltodextrin 20kg, microcrystalline cellulose 13kg; Drop into successively in V mixer, fully mix, obtain mixture 100kg;
3) by 95% ethanol softwood processed for mixture, vibratory sieve is granulated;
4) dressing
Take hydroxypropyl methylcellulose 2kg, be made into 6% coating solution with 60% ethanol; Dressing control dressing kettle temperature is at 35-40 DEG C, controls turn at 30-35/min of rotating speed, evenly sprays into coating solution with high-pressure spray gun, and constantly stirs particle, until coating solution bag is complete, takes out, and drying under reduced pressure 2h, obtains qualified particle;
5) qualified particle is filled to the hard shell capsules of every of 0.3g at capsule filling machine by 1# capsule shells, polishing, then makes aluminium-plastic panel, and mounted box, makes finished product;
In this finished product, mogroside V content is 6000mg/100g, and O-acetyl content is 1500mg/100g.
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| CN201310304981.4 | 2013-07-19 | ||
| CN201410249190.0A CN104068395B (en) | 2013-07-19 | 2014-06-06 | The aloe Momordica grosvenori compound capsule that a kind of antioxidation is strong |
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| CN201410249270.6A Active CN104068396B (en) | 2013-07-19 | 2014-06-06 | A kind of Aloe Fructus Momordicae compound capsule |
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| CN103349283A (en) * | 2013-07-19 | 2013-10-16 | 桂林电子科技大学 | Aloe and momordica grosvenori compound capsule with oxidation prevention function |
| CN104068408B (en) * | 2014-06-03 | 2016-05-11 | 桂林三宝药业有限公司 | The aloe Momordica grosvenori compound capsule that a kind of mogroside IV content is high |
| CN104068391B (en) * | 2014-06-05 | 2016-05-11 | 桂林三宝生物科技有限公司 | The aloe Momordica grosvenori compound capsule that a kind of mogroside IV content is high |
| CN105166091A (en) * | 2015-04-28 | 2015-12-23 | 三江侗族自治县仙池茶业有限公司 | Mogroside natural antioxidant containing sweet tea seed oil |
| CN105053778A (en) * | 2015-08-23 | 2015-11-18 | 洛阳维尔健生物工程有限公司 | Aloe and xylooligosaccharide soft capsule capable of loosening bowel to relieve constipation and preparation method of aloe and xylooligosaccharide soft capsule |
| CN106731929A (en) * | 2016-12-13 | 2017-05-31 | 完美（中国）有限公司 | One kind realizes various granule materials and the mixed uniformly technique of various powders material and its application and device |
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| CN1830328A (en) * | 2005-03-08 | 2006-09-13 | 郭伟光 | Aloe health-care beverage and its preparation method |
| CN102240360A (en) * | 2010-07-05 | 2011-11-16 | 孟昭滨 | Bowel clearing and detoxifying infusion |
| CN103349283A (en) * | 2013-07-19 | 2013-10-16 | 桂林电子科技大学 | Aloe and momordica grosvenori compound capsule with oxidation prevention function |
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| CN1199680C (en) * | 2002-12-16 | 2005-05-04 | 唐第光 | Healthy food for loosing bowel to relieve constipation |
| JP2006204217A (en) * | 2005-01-28 | 2006-08-10 | Daiwa Enterprise Kk | Food supplement and method for producing food supplement |
| JP2008074792A (en) * | 2006-09-22 | 2008-04-03 | Oriza Yuka Kk | Composition for anti-fatigue use |
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| CN1830328A (en) * | 2005-03-08 | 2006-09-13 | 郭伟光 | Aloe health-care beverage and its preparation method |
| CN102240360A (en) * | 2010-07-05 | 2011-11-16 | 孟昭滨 | Bowel clearing and detoxifying infusion |
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| CN104068395A (en) | 2014-10-01 |
| CN103349283A (en) | 2013-10-16 |
| CN104068396A (en) | 2014-10-01 |
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Application publication date: 20141001 Assignee: Guilin Xinjiatianxia Food Co.,Ltd. Assignor: GUILIN University OF ELECTRONIC TECHNOLOGY Contract record no.: X2023980046008 Denomination of invention: A kind of aloe and siraitia grosvenorii compound capsule with strong antioxidant effect Granted publication date: 20160511 License type: Common License Record date: 20231108 |