CN104055975A - Anti-tumor traditional Chinese medicine preparation - Google Patents
Anti-tumor traditional Chinese medicine preparation Download PDFInfo
- Publication number
- CN104055975A CN104055975A CN201410325193.8A CN201410325193A CN104055975A CN 104055975 A CN104055975 A CN 104055975A CN 201410325193 A CN201410325193 A CN 201410325193A CN 104055975 A CN104055975 A CN 104055975A
- Authority
- CN
- China
- Prior art keywords
- grams
- chinese medicine
- gram
- medicine preparation
- herba
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 52
- 238000002360 preparation method Methods 0.000 title claims abstract description 32
- 230000000259 anti-tumor effect Effects 0.000 title abstract description 7
- 239000010231 banlangen Substances 0.000 claims abstract description 14
- 210000000582 semen Anatomy 0.000 claims abstract description 14
- 241000005787 Cistanche Species 0.000 claims abstract description 5
- 229910052957 realgar Inorganic materials 0.000 claims abstract description 5
- 241000283956 Manis Species 0.000 claims description 13
- 241000195474 Sargassum Species 0.000 claims description 13
- 241001092084 Agrimonia Species 0.000 claims description 9
- 235000016993 Agrimonia Nutrition 0.000 claims description 9
- 241000555712 Forsythia Species 0.000 claims description 9
- 230000000118 anti-neoplastic effect Effects 0.000 claims description 8
- 239000002994 raw material Substances 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 23
- 208000024891 symptom Diseases 0.000 abstract description 11
- 239000008280 blood Substances 0.000 abstract description 7
- 210000004369 blood Anatomy 0.000 abstract description 7
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 6
- 230000017531 blood circulation Effects 0.000 abstract description 6
- 208000026435 phlegm Diseases 0.000 abstract description 6
- 230000001737 promoting effect Effects 0.000 abstract description 6
- 208000002193 Pain Diseases 0.000 abstract description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 5
- 201000010099 disease Diseases 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 4
- 230000002588 toxic effect Effects 0.000 abstract description 4
- 230000001105 regulatory effect Effects 0.000 abstract description 3
- 239000000463 material Substances 0.000 abstract description 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 abstract 2
- 244000307697 Agrimonia eupatoria Species 0.000 abstract 1
- 241001474374 Blennius Species 0.000 abstract 1
- 241001082427 Euphorbia lunulata Species 0.000 abstract 1
- 241001282397 Manis pentadactyla Species 0.000 abstract 1
- 241000301400 Trogopterus Species 0.000 abstract 1
- 235000000125 common agrimony Nutrition 0.000 abstract 1
- 210000003608 fece Anatomy 0.000 abstract 1
- 235000010333 potassium nitrate Nutrition 0.000 abstract 1
- 239000004323 potassium nitrate Substances 0.000 abstract 1
- 238000011282 treatment Methods 0.000 description 32
- 206010028980 Neoplasm Diseases 0.000 description 21
- 210000004185 liver Anatomy 0.000 description 11
- 210000004072 lung Anatomy 0.000 description 5
- 231100000614 poison Toxicity 0.000 description 5
- 210000000952 spleen Anatomy 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 230000008961 swelling Effects 0.000 description 5
- 239000003440 toxic substance Substances 0.000 description 5
- 231100000419 toxicity Toxicity 0.000 description 5
- 230000001988 toxicity Effects 0.000 description 5
- 239000003172 expectorant agent Substances 0.000 description 4
- 230000003419 expectorant effect Effects 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 238000005728 strengthening Methods 0.000 description 4
- 206010011224 Cough Diseases 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 244000045947 parasite Species 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 238000012913 prioritisation Methods 0.000 description 3
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 2
- 208000026310 Breast neoplasm Diseases 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- 206010008479 Chest Pain Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 239000002934 diuretic Substances 0.000 description 2
- 230000001882 diuretic effect Effects 0.000 description 2
- 238000001647 drug administration Methods 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 2
- 210000000232 gallbladder Anatomy 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 238000001959 radiotherapy Methods 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
- 206010065553 Bone marrow failure Diseases 0.000 description 1
- 208000018084 Bone neoplasm Diseases 0.000 description 1
- 208000017897 Carcinoma of esophagus Diseases 0.000 description 1
- 206010048610 Cardiotoxicity Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 206010020674 Hypermetabolism Diseases 0.000 description 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 208000001435 Thromboembolism Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000031975 Yang Deficiency Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000003698 anagen phase Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 208000035269 cancer or benign tumor Diseases 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000315 carcinogenic Toxicity 0.000 description 1
- 231100000259 cardiotoxicity Toxicity 0.000 description 1
- 230000007681 cardiovascular toxicity Effects 0.000 description 1
- 230000032823 cell division Effects 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 231100001157 chemotherapeutic toxicity Toxicity 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 238000009104 chemotherapy regimen Methods 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000007937 eating Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 201000005619 esophageal carcinoma Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 208000010749 gastric carcinoma Diseases 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 229960001680 ibuprofen Drugs 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 210000003716 mesoderm Anatomy 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 210000004224 pleura Anatomy 0.000 description 1
- 201000003437 pleural cancer Diseases 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- RZJQGNCSTQAWON-UHFFFAOYSA-N rofecoxib Chemical compound C1=CC(S(=O)(=O)C)=CC=C1C1=C(C=2C=CC=CC=2)C(=O)OC1 RZJQGNCSTQAWON-UHFFFAOYSA-N 0.000 description 1
- 229960000371 rofecoxib Drugs 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 201000000498 stomach carcinoma Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an anti-tumor traditional Chinese medicine preparation which comprises the following crude drugs in parts by weight: 10-20g of processed semen strychni, 10-20g of trogopterus dung, 5-10g of hairyvein agrimony, 5-10g of potassium nitrate, 5-10g of realgar, 8-12g of radix isatidis, 8-15g of arisacma consanguineum, 10-20g of seaweed, 8-12g of fructus forsythiae, 10-20g of euphorbia lunulata, 5-10g of manis pentadactyla, 5-10g of calculus bovis and 5-10g of desert cistanche. The anti-tumor traditional Chinese medicine preparation is based on the principle of treating both symptoms and root cause of diseases of traditional Chinese medicine, has the effects of regulating vital energy and silting to relieve pain, clearing away heat and toxic materials, dissolving phlegm to remove stasis, promoting blood circulation to remove blood stasis and tonifying qi and yin, and has the advantages of rapid curative effect, high cure rate, safety, convenience, no toxic and side effects, low cost and the like in the anti-tumor aspect.
Description
Technical field
The invention belongs to the field of Chinese medicines, a kind of specifically can antineoplastic Chinese medicine preparation.
Background technology
Tumor be body tissue cell under the long term of inside and outside harmful factor, on gene level, lost the normal regulation to its growth, there is the neoplasm that hyperplasia and abnormal differentiation form, often with the form of lump, occur clinically.Once tumor forms, malignant tumor particularly, it is grown to autonomy, by cell division, entails filial generation, and growth phase, to not limited by body, is grown vigorous, and has aggressive and transitivity, and body is worked the mischief.Tumor incidence is higher, and China's case load is quite huge, has data to show and accounts for 55% of whole world case load.
Modern medicine thinks, the cause of disease of tumor is very complicated, be usually that a kind of carcinogenic factor can be brought out kinds of tumors, and a kind of tumor may have Different types of etiopathogenises.The hereditary material that most tumors are environmental factors and cell interacts and causes.Its clinical symptoms main manifestations is that body occurs that lump, pain, pathologic secretions, ulcer, hemorrhage, heating, cough, health are weak etc.Its pathogeneticing characteristic is paracytic growth out of control, and is sent out to other position by original site, and this sending out as uncontrollable exhaustion finally causes death by infringement critical organ with causing.
Modern medicine is a lot of at method and the medicine of anti-tumor aspect, doctor trained in Western medicine Radiotherapy chemotherapy, operative treatment malignant tumor curative effect are certainly, but toxic and side effects is large, main manifestations is bone marrow depression, gastrointestinal reaction, hepatic and renal function damage, cardiac toxicity etc., and medical expense is expensive, a lot of patients, owing to being difficult to bear high medical expense, affect the state of an illness adversely.Though Chinese medicine toxic and side effects is little, the most antitumor onset of existing medicine is slow, the course for the treatment of is long, seems unable to do what one wishes.
Summary of the invention
The invention solves the defect existing at anti-tumor aspect at present, a kind of stable curative effect, cheap is provided, can significantly improve body's immunity, accelerate physical recovery, alleviate Radiotherapy chemotherapy toxicity, improve the antineoplastic Chinese medicine preparation of long term survival rate.
The technical solution adopted in the present invention is: a kind of antineoplastic Chinese medicine preparation, it is characterized in that, and described Chinese medicine preparation comprises the Chinese herb of following weight in grams:
Semen Strychni (processed) 10-20 gram, Oletum Trogopterori 10-20 gram, Herba Agrimoniae 5-10 gram, Sal Nitri 5-10 gram, Realgar 5-10 gram, Radix Isatidis 8-12 gram, Rhizoma Arisaematis (processed) 8-15 gram, Sargassum 10-20 gram, Fructus Forsythiae 8-12 gram, Herba euphorbiae lunulatae 10-20 gram, Squama Manis 5-10 gram, Calculus Bovis 5-10 gram, Herba Cistanches 5-10 gram.
As this kind of prioritization scheme:
Described Chinese medicine preparation comprises the Chinese herb of following weight in grams:
10 grams of Semen Strychni (processed)s, 10 grams of Oletum Trogopteroris, 5 grams of Herba Agrimoniaes, 5 grams of Sal Nitri, 5 grams of Realgars, 8 grams of Radix Isatidis, 8 grams of Rhizoma Arisaematis (processed), 10 grams of Sargassums, 8 grams of Fructus Forsythiaes, 10 grams of Herba euphorbiae lunulataes, 5 grams of Squama Maniss, 5 grams of Calculus Boviss, 5 grams of Herba Cistanchess.
As this kind of prioritization scheme:
Described Chinese medicine preparation comprises the Chinese herb of following weight in grams:
15 grams of Semen Strychni (processed)s, 15 grams of Oletum Trogopteroris, 8 grams of Herba Agrimoniaes, 8 grams of Sal Nitri, 8 grams of Realgars, 10 grams of Radix Isatidis, 12 grams of Rhizoma Arisaematis (processed), 15 grams of Sargassums, 10 grams of Fructus Forsythiaes, 15 grams of Herba euphorbiae lunulataes, 8 grams of Squama Maniss, 8 grams of Calculus Boviss, 8 grams of Herba Cistanchess.
As this kind of prioritization scheme:
Described Chinese medicine preparation comprises the Chinese herb of following weight in grams:
20 grams of Semen Strychni (processed)s, 20 grams of Oletum Trogopteroris, 10 grams of Herba Agrimoniaes, 10 grams of Sal Nitri, 10 grams of Realgars, 12 grams of Radix Isatidis, 15 grams of Rhizoma Arisaematis (processed), 20 grams of Sargassums, 12 grams of Fructus Forsythiaes, 20 grams of Herba euphorbiae lunulataes, 10 grams of Squama Maniss, 10 grams of Calculus Boviss, 10 grams of Herba Cistanchess.
The instructions of taking of above-mentioned Chinese medicine preparation is: after the raw material Chinese medicine of above-mentioned weight proportion is mixed, according to the method for the fried Chinese medicine of tradition, get its medicine juice, 1 dose of every day, minutes 3～4 times oral, and 30 doses was 1 course for the treatment of.Between the course for the treatment of, drug withdrawal is 2～3 days, then goes lower 1 course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Semen Strychni (processed), bitter in the mouth, cold in nature; Return liver, spleen channel.There is the heat radiation of invigorating blood circulation, the effect of reducing swelling and alleviating pain.
Oletum Trogopterori, sweet in the mouth, warm in nature; Return Liver Channel.There is dredging blood vessel, the effect of eliminating stasis to stop pain.
Herba Agrimoniae, bitter in the mouth, cold in nature; GUIXIN, Liver Channel.There is astringing to arrest bleeding, tonify deficiency removing food stagnancy, dysentery relieving parasite killing, the effect of removing toxic substances and promoting subsidence of swelling.
Sal Nitri, bitter in the mouth, pungent, cold nature; Return liver, gallbladder meridian.Having induces sweat brings down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, the effect of elevate a turnable ladder yang-energy.
Realgar, bitter in the mouth, pungent is warm in nature, flat; GUIXIN, liver, stomach, lung meridian.There is removing toxic substances parasite killing, the effect of removing dampness and eliminating phlegm.
Radix Isatidis, bitter in the mouth, cold in nature; GUIXIN, stomach warp.There is heat-clearing and toxic substances removing, the effect of hemostasis removing heat from blood.
Rhizoma Arisaematis (processed), bitter in the mouth, pungent, warm in nature; Return lung, liver, spleen channel.There is drying dampness to eliminate phlegm, expelling wind to relieve convulsion, the effect of mass dissipating and swelling eliminating.
Sargassum, bitter in the mouth, salty, cold in nature; Return lung, stomach, spleen channel.There is hard masses softening and resolving, the effect of expectorant diuretic.
Fructus Forsythiae, bitter in the mouth, cold nature; Return lung, the heart, gallbladder meridian.There is heat-clearing and toxic substances removing, the effect of eliminating carbuncle eliminating stagnation.
Herba euphorbiae lunulatae, bitter in the mouth, pungent, cool in nature; Return lung, stomach, liver, spleen channel.Have relieving cough and expelling phlegm, eliminating stagnation is relieved oedema or abdominal distension through diuresis or purgation, the effect of the parasite killing of drawing out pus by applying a plaster to the affected part.
Squama Manis, salty in the mouth, cold nature; Return liver, stomach warp.There is blood circulation promoting and dispersing pathogen accumulation, the stimulating milk secretion of stimulating the menstrual flow, the effect of the routed heavily fortified point of eliminating carbuncle.
Calculus Bovis, sweet in the mouth, cool in nature; GUIXIN, Liver Channel.There is clearing away heart-fire and eliminating phlegm, the effect of the cool liver of having one's ideas straightened out.
Herba Cistanches, sweet in the mouth, salty, warm in nature; Return kidney, large intestine channel.There is kidney-reinforcing Yang-strengthening, the effect of loosening bowel to relieve constipation.
The traditional Chinese medical science thinks that the cause of disease of tumor is that exopathogen invasion and attack, disorder of emotion, eating and drinking without temperance and labor are wanted internal injury etc.Pathogenesis is vital QI being weakened and pathogen being violent, simulataneous insufficiency and excessive.Weakened body resistance yang deficiency, the deficiency of YIN, the gas yin and yang imbalance of being mainly, the domination of pathogen is mainly that the stagnation of QI, expectorant are solidifying, blood stasis, pyretic toxicity etc.Therefore treatment should be adhered to the principle of blood circulation promoting and blood stasis dispelling, expectorant damp eliminating, strengthening vital QI to eliminate pathogenic factors.In Chinese medicine preparation of the present invention, Semen Strychni (processed), Oletum Trogopterori can blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain; Herba Agrimoniae, Radix Isatidis, Fructus Forsythiae can heat-clearing and toxic substances removing, hemostasis removing heat from blood; Realgar, Calculus Bovis, Rhizoma Arisaematis (processed), Herba euphorbiae lunulatae can drying dampness to eliminate phlegm, and mass dissipating and swelling eliminating again can sensible cool liver, and eliminating stagnation is relieved oedema or abdominal distension through diuresis or purgation; Sargassum, Squama Manis can hard masses softening and resolving, expectorant diuretic, promoting blood circulation to restore menstrual flow; Sal Nitri can induce sweat and bring down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI; Herba Cistanches can kidney-reinforcing Yang-strengthening, invigorating the spleen and benefiting QI, the body resistance strengthening and constitution consolidating.All medicines totally 5, can QI and blood regulating, regulating YIN and YANG, training revisal gas, cleaning " malicious source ", improves mesenchyma stroma of tumors cell function and reaches anticancer object of saving one's life.
For further investigating the clinical efficacy of medicine of the present invention, we have selected 150 routine patients to carry out clinical trial, male 98 examples, female's 52 examples, age 28-70 year, 56 years old mean age.All through cytology or pathology, make a definite diagnosis, KPS scoring > 60 minutes, expectation > life cycle 3 months, nonsmall-cell lung cancer 32 examples wherein, breast carcinoma 38 examples, 24 Cases of Gastric Carcinoma, esophageal carcinoma 22 examples, non-Hodgkin lymphoma 12 examples, colorectal cancer 22 examples, are and just control patient.Be divided at random treatment group and matched group, every group of 75 examples.Two groups of case features are at aspect zero differences such as age, sex, behavioral aspect, tumor classification, chemotherapy regimens.
Criterion of therapeutical effect (according to WHO solid tumor drugs treatment efficacy assessment standard):
Alleviate completely (CR): tumor is cured completely, it is normal that physical symptom recovers.
Partial rcsponse (PR): tumor area reducing is obvious, and physical symptom obviously improves.
Stable (SD): tumor area is unchanged, and physical symptom is maintained the statusquo.
Worsen (PD): tumor area change, physical symptom worsens.
Separately, toxicity is carried out toxicity assessment by WHO toxicity of anticancer agents reaction calibration (0-IV).
Therapeutic Method:
Treatment group is taken the Chinese medicine preparation of embodiment 2, according to the method for the fried Chinese medicine of tradition, gets its medicine juice, and 1 dose of every day, minutes 3～4 times oral, and 30 doses was 1 course for the treatment of.Between the course for the treatment of, drug withdrawal is 2～3 days, then goes lower 1 course for the treatment of.Matched group is taked operation, chemicotherapy, thromboembolism according to symptom degree, adds Western medicine auxiliary treatment such as coordinating ibuprofen, rofecoxib.
Efficacy result:
That adds up patient's drug administration the results are shown in Table 1.Treat after three courses for the treatment of the total effective rate 74.7% for the treatment of group; Matched group total effective rate 46.7%; Two groups of comparisons, treatment group curative effect is apparently higher than matched group.
Table 1: add up two groups of patient's drug administration result synopsis
Untoward reaction:
Treatment group WBC reduces 46 examples (61.3%); Matched group WBC reduces 58 examples (77.3%), and treatment group group WBC is obviously less than matched group, significant difference (P < 0.05).The incidence rate of observation group's platelet, anemia is a little less than matched group, but difference not statistically significant.In Table 2.
Table 2: add up the toxicity after two groups of patient treatments
Note: compare * P < 0.05 with matched group
Result shows, Chinese medicine preparation of the present invention is taken has the significantly anti-activity of controlling afterwards to tumor cell, can significantly improve patient's body immunity, kill and suppress tumor (cancer) cell, cure rate is high, relapse rate is low, human body is had no side effect, greatly improved patient's long term survival rate, clinic application and popularization.
The specific embodiment
Embodiment 1: a kind of antineoplastic Chinese medicine preparation, choose 10 grams of Semen Strychni (processed)s, 10 grams of Oletum Trogopteroris, 5 grams of Herba Agrimoniaes, 5 grams of Sal Nitri, 5 grams of Realgars, 8 grams of Radix Isatidis, 8 grams of Rhizoma Arisaematis (processed), 10 grams of Sargassums, 8 grams of Fructus Forsythiaes, 10 grams of Herba euphorbiae lunulataes, 5 grams of Squama Maniss, 5 grams of Calculus Boviss, 5 grams of Herba Cistanchess.
Embodiment 2: a kind of antineoplastic Chinese medicine preparation, choose 15 grams of Semen Strychni (processed)s, 15 grams of Oletum Trogopteroris, 8 grams of Herba Agrimoniaes, 8 grams of Sal Nitri, 8 grams of Realgars, 10 grams of Radix Isatidis, 12 grams of Rhizoma Arisaematis (processed), 15 grams of Sargassums, 10 grams of Fructus Forsythiaes, 15 grams of Herba euphorbiae lunulataes, 8 grams of Squama Maniss, 8 grams of Calculus Boviss, 8 grams of Herba Cistanchess.
Embodiment 3: a kind of antineoplastic Chinese medicine preparation, choose 20 grams of Semen Strychni (processed)s, 20 grams of Oletum Trogopteroris, 10 grams of Herba Agrimoniaes, 10 grams of Sal Nitri, 10 grams of Realgars, 12 grams of Radix Isatidis, 15 grams of Rhizoma Arisaematis (processed), 20 grams of Sargassums, 12 grams of Fructus Forsythiaes, 20 grams of Herba euphorbiae lunulataes, 10 grams of Squama Maniss, 10 grams of Calculus Boviss, 10 grams of Herba Cistanchess.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is further verified:
Case 1
Wang, female, 56 years old.Patient checked prompting rumpbone single-shot tumor before 3 years, and patient Pao Liaoduojia hospital, has used many medicines, expensive but also have no sign of improvement.In line with the psychology of trying, take Chinese medicine preparation embodiment 3 treatments of the present invention, get off a course for the treatment of, and the state of an illness is improved greatly, and symptom has not had substantially, continues to take two courses for the treatment of and is consolidated, and patient has recovered daily life at present, follows up a case by regular visits to 2 years without recurrence.
Case 2
Lee, female, 70 years old this year.Patient checked and suffers from breast tumor in March, 2010, i.e. operation, recurrence again after half a year.Consider that patient age is bigger than normal, operation risk is high again.Therefore upon somebody's introduction, start to take Chinese medicine preparation embodiment of the present invention 2 treatments, after three courses for the treatment of, tumor disappears substantially, and patient body situation is greatly improved, and treats so far tumor symptom without recurrence.
Case 3
Hu, man, 61 years old.Patient's readme is weak because occurring, dizzy, the symptom of becoming thin, have palpitation the year before, and the medical Yu Mou city Second Academy is diagnosed as " the fine tumor of bone ".Adopt Chinese medicine preparation embodiment 1 treatment of the present invention, after 10 days, tired weak situation is clearly better, and patient's confidence increases, requirement continues to take, and adjusts each Chinese medicine dose according to the state of an illness in good time, after one and half courses for the treatment of, patient is conscious before strength, and night sweat alleviates, and appetite takes a turn for the better.Proceed after treatment, take again two courses for the treatment of, patient body is good so far, recovers orthobiosis.Follow up a case by regular visits to so far without recurrence.
Case 4
Cao, man, 63 years old.Patient started sensation left side chest pain often in 2012, dyspnea, with symptoms such as cough, abundant expectoration, breaks as malignant pleural tumor through local hospital inspection disease.Patient refuses operation, is intent on adopting treatment by Chinese herbs.Take after being introduced Chinese medicine preparation of the present invention after the course for the treatment of, patient feels that chest pain alleviates, and complexion is also good, continue to take, after the treatment of 4 courses for the treatment of, check PET-CT shows that left side pleura hypermetabolism tuberosity and little strip focus disappear substantially, and patient is almost recovered.Follow up a case by regular visits to so far without recurrence.
Claims (4)
1. an antineoplastic Chinese medicine preparation, is characterized in that, described Chinese medicine preparation comprises the Chinese herb of following weight in grams:
Semen Strychni (processed) 10-20 gram, Oletum Trogopterori 10-20 gram, Herba Agrimoniae 5-10 gram, Sal Nitri 5-10 gram, Realgar 5-10 gram, Radix Isatidis 8-12 gram, Rhizoma Arisaematis (processed) 8-15 gram, Sargassum 10-20 gram, Fructus Forsythiae 8-12 gram, Herba euphorbiae lunulatae 10-20 gram, Squama Manis 5-10 gram, Calculus Bovis 5-10 gram, Herba Cistanches 5-10 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is comprised of the raw material of following weight portion:
10 grams of Semen Strychni (processed)s, 10 grams of Oletum Trogopteroris, 5 grams of Herba Agrimoniaes, 5 grams of Sal Nitri, 5 grams of Realgars, 8 grams of Radix Isatidis, 8 grams of Rhizoma Arisaematis (processed), 10 grams of Sargassums, 8 grams of Fructus Forsythiaes, 10 grams of Herba euphorbiae lunulataes, 5 grams of Squama Maniss, 5 grams of Calculus Boviss, 5 grams of Herba Cistanchess.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is comprised of the raw material of following weight portion:
15 grams of Semen Strychni (processed)s, 15 grams of Oletum Trogopteroris, 8 grams of Herba Agrimoniaes, 8 grams of Sal Nitri, 8 grams of Realgars, 10 grams of Radix Isatidis, 12 grams of Rhizoma Arisaematis (processed), 15 grams of Sargassums, 10 grams of Fructus Forsythiaes, 15 grams of Herba euphorbiae lunulataes, 8 grams of Squama Maniss, 8 grams of Calculus Boviss, 8 grams of Herba Cistanchess.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is comprised of the raw material of following weight portion:
20 grams of Semen Strychni (processed)s, 20 grams of Oletum Trogopteroris, 10 grams of Herba Agrimoniaes, 10 grams of Sal Nitri, 10 grams of Realgars, 12 grams of Radix Isatidis, 15 grams of Rhizoma Arisaematis (processed), 20 grams of Sargassums, 12 grams of Fructus Forsythiaes, 20 grams of Herba euphorbiae lunulataes, 10 grams of Squama Maniss, 10 grams of Calculus Boviss, 10 grams of Herba Cistanchess.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410325193.8A CN104055975B (en) | 2014-07-01 | 2014-07-01 | A kind of antitumor Chinese medicine preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410325193.8A CN104055975B (en) | 2014-07-01 | 2014-07-01 | A kind of antitumor Chinese medicine preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104055975A true CN104055975A (en) | 2014-09-24 |
| CN104055975B CN104055975B (en) | 2018-11-02 |
Family
ID=51544094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410325193.8A Active CN104055975B (en) | 2014-07-01 | 2014-07-01 | A kind of antitumor Chinese medicine preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104055975B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412835A (en) * | 2015-12-17 | 2016-03-23 | 陈贵敏 | Traditional Chinese medicine preparation for treating esophagus benign tumor |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103566282A (en) * | 2012-07-27 | 2014-02-12 | 西安正大制药有限公司 | Traditional Chinese medicine composition with anti-tumor effect and preparation method thereof |
-
2014
- 2014-07-01 CN CN201410325193.8A patent/CN104055975B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103566282A (en) * | 2012-07-27 | 2014-02-12 | 西安正大制药有限公司 | Traditional Chinese medicine composition with anti-tumor effect and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘静宇等主编: "《防癌治癌小绝招——民间土单秘验良方妙法》", 30 April 1994 * |
| 李汉义: "《中国民间偏方大全》", 31 March 2013 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412835A (en) * | 2015-12-17 | 2016-03-23 | 陈贵敏 | Traditional Chinese medicine preparation for treating esophagus benign tumor |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104055975B (en) | 2018-11-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103356973B (en) | Antineoplastic traditional Chinese medicine | |
| CN101745065B (en) | Pharmaceutical composition with effects of resisting cancer and alleviating pain | |
| CN104225441A (en) | Traditional Chinese medicine composition for treating stomach trouble and preparation method of granules and capsules of traditional Chinese medicine composition | |
| CN102406902A (en) | Traditional Chinese medicine composition for treating hyperplasia of mammary glands | |
| CN102688317A (en) | Traditional Chinese medicine for treating liver cancer | |
| CN102626508B (en) | Traditional Chinese medicine composite for curing liver cancer | |
| CN101313952A (en) | Traditional Chinese herb medicine for treating cancer | |
| CN104547313B (en) | It is a kind of to treat lung cancer, breast cancer, the medicine of lymph cancer and preparation method | |
| CN101612358B (en) | Anticancer dispersing paste and preparation method thereof | |
| CN103784932A (en) | Traditional Chinese medicine decoction for treating hyperplasia of mammary glands | |
| CN104258362A (en) | Traditional Chinese medicine preparation for treating peripheral neuritis | |
| CN104055975A (en) | Anti-tumor traditional Chinese medicine preparation | |
| CN103239519B (en) | Anticancer pain-relieving traditional Chinese medicine composition | |
| CN101919967B (en) | Traditional Chinese drug for treating esophagus cancer | |
| CN104873692A (en) | Traditional Chinese medicine preparation for treating esophagus cancer | |
| CN104147254A (en) | Traditional Chinese medicine preparation for treating leucocytopenia after chemotherapy | |
| CN103505670A (en) | Traditional Chinese medicine composition for treating primary bronchus lung cancer | |
| CN103705853A (en) | Cancer-eliminating and stasis-dissolving pill | |
| CN103316061A (en) | Traditional Chinese medicinal mixture for treating cancer and preparation method thereof | |
| CN103040968B (en) | Anticancer Yanshouling | |
| CN101549074A (en) | Drug for treating hyperplasia of mammary glands | |
| CN105617099A (en) | Medicine for treating adverse reactions caused by tumor chemotherapy and preparation method | |
| CN104491613A (en) | Traditional Chinese medicine formula for treating gastrointestinal cancer | |
| CN104800693B (en) | A kind of Chinese medicine composition for treating lung cancer | |
| CN104096172A (en) | Traditional Chinese medicine preparation capable of resisting malignant tumors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Yan Inventor after: Xu Bao Inventor after: Wang Guoliang Inventor after: Xu Zhaomin Inventor after: Cui Liping Inventor after: Xu Yanqing Inventor after: Wu Mingxia Inventor before: Cui Liping Inventor before: Xu Yanqing Inventor before: Wu Mingxia |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20180918 Address after: 350200 305 units of 1 buildings in Jinjiang garden three District, Changle District, Fuzhou, Fujian, China Applicant after: The permanently happy head of district in Fuzhou City wins Information Technology Co.,Ltd. Address before: 262700 Shouguang people's Hospital, 45 health Street, Shouguang, Shandong Applicant before: Cui Liping |
|
| TA01 | Transfer of patent application right | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20200415 Address after: No. 16, Laiwu Pharmaceutical Industrial Park, Kou Town, Laiwu District, Jinan City, Shandong Province Patentee after: SHANDONG HEBAO PHARMACEUTICAL Co.,Ltd. Address before: 350200 305 units of 1 buildings in Jinjiang garden three District, Changle District, Fuzhou, Fujian, China Patentee before: The permanently happy head of district in Fuzhou City wins Information Technology Co.,Ltd. |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: An Antitumor Traditional Chinese Medicine Preparation Effective date of registration: 20230824 Granted publication date: 20181102 Pledgee: Laiwu Shandong rural commercial bank Limited by Share Ltd. Pledgor: SHANDONG HEBAO PHARMACEUTICAL Co.,Ltd. Registration number: Y2023980053684 |