CN104013905B - Traditional Chinese medicine formula for treating mycoplasmal pneumonia and application thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine formula for treating mycoplasmal pneumonia. The traditional Chinese medicine formula is prepared from the following traditional Chinese medicine raw materials: 6-12 parts of the root bark of the peony tree, 9-15 parts of radix rehmanniae recen, 6-12 parts of radix scrophulariae, 6-12 parts of honeysuckle flower, 6-9 parts of fructus forsythiae, 6-12 parts of scutellaria baicalensis, 1.5-3 parts of ephedra, 6-9 parts of almond, 6-12 parts of curcuma zedoary, 6-12 parts of Chinese angelica, 6-12 parts of peach kernel, 6-12 parts of codonopsis pilosula, 9-15 parts of bighead atractylodes rhizome and 6-12 parts of liquorice. The traditional Chinese medicine formula is reasonable in compatibility of medicines, convenient to process and low in cost, does not have toxic or side effect and has an obvious effect of treating the mycoplasmal pneumonia.

Description

A kind of Chinese prescription treating mycoplasma pneumoniae pneumonia and its application

Technical field

The invention belongs to modern Chinese traditional medicine field and in particular to a kind of Chinese prescription treating mycoplasma pneumoniae pneumonia and its Application in preparation treatment mycoplasma pneumoniae pneumonia pharmaceutical preparation.

Background technology

Mycoplasma pneumoniae pneumonia is the pneumonia being caused by mycoplasma pneumoniae, once claims primary atypical pneumonia.It is apt to occur in Child or adolescent, accounts for the 15%～30% of pneumonia sum, popular year may be up to 40%～60%.Mycoplasma pneumoniae pneumonia rises Disease is slow, about 2～3 weeks incubation periods, and disease just has general malaise, weak, headache.Heating body temperature occurred after 2～3 days and often reaches 39 DEG C of left sides The right side, sustainable 1～3 week, can be with pharyngalgia and muscular soreness.Cough for primary disease project symptom, typically opened in after being ill 2～3 days Begin, just for dry cough, after switch to intractable play and cough, often have sticky sputum occasionally to carry the blood streak, minority case can be similar to pertussis sample apasm of coughing. Sustainable 1～4 week.How inconspicuous physical signs of lung is, or even completely without.Minority can hear dry, wet music.But polylith disappears, therefore body Levy the clinical manifestation such as cough with play and generate heat inconsistent, be one of primary disease feature.Infant onset is anxious, and the course of disease is long, and the state of an illness is heavier, table Now be dyspnea, breathe heavily suppress, sound of stridulating more prominent, pulmonary's signal to noise ratio Annual wool yield is many.Part infant child can be lean with hemolytic Blood, meningitiss, myocarditiss, groan, Green-Pulmonary hypofuntion such as sharp syndromes.

The suitable antibacterials of early application can mitigation symptoms and shorten the course of disease, Macrolide antibacterials be first-selection, such as Erythromycin, Roxithromycin and Azithromycin.Fluoroquinolones such as Levofloxacin, Gatifloxacin and Moxifloxacin etc., tetracycline Class is also used for the treatment of mycoplasma pneumoniae pneumonia.General 2～3 weeks of the course for the treatment of.Not only controlled using western medicine mycoplasma pneumoniae pneumonia The treatment time is long, and side effect is strong, the growth of impact child, therefore finds effect substantially, short treating period and the medicine having no toxic side effect It is problem demanding prompt solution.Finding the active drug that activity is strong, have no toxic side effect from traditional medicine becomes this problem of solution New way.

Content of the invention

It is an object of the invention to provide a kind of effect is significant, have no toxic side effect, medication is convenient, treatment lung with low cost The Chinese prescription of scorching mycoplasma pneumonia, for realizing object above, the technical solution used in the present invention is：

A kind of Chinese prescription treating mycoplasma pneumoniae pneumonia is it is characterised in that described Chinese prescription is by following mass parts Raw material of Chinese medicine be formulated：Cortex Moutan (Paeonia suffruticosaAndr.) 6-12 part, Radix Rehmanniae (Rehmannia Glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.) 9-15 part, Radix Scrophulariae (Scrophularia Ningpoensis Hemsl.) 6-12 part, Flos Lonicerae (Lonicera japonica Thunb.) 6-12 part, Fructus Forsythiae (Forsythia Suspensa (Thunb.) Vahl) 6-9 part, Radix Scutellariae (Scutellaria Linn.) 6-12 part, Herba Ephedrae (Ephedra sinica Stapf) 1.5-3 part, Semen Armeniacae Amarum (Amygdalus Communis Vas) 6-9 part, Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc) 6-12 part, Radix Angelicae Sinensis (Angelica sinensis) 6-12 part, Semen Persicae (semenpersicae, Peachseed) 6-12 part, Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.) 6-12 part, the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) 9-15 part, Radix Glycyrrhizae (Radix Glycyrrhizae) 6-12 part.

Preferably, the Chinese prescription of the present invention is formulated by the raw material of Chinese medicine of following mass parts：Cortex Moutan (Paeonia Suffruticosa Andr.) 9 parts, Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.) 15 parts, 9 parts of Radix Scrophulariae (Scrophularia ningpoensis Hemsl.), Flos Lonicerae (Lonicera japonica Thunb.) 9 parts, 6 parts of Fructus Forsythiae (Forsythia suspensa (Thunb.) Vahl), Radix Scutellariae (Scutellaria Linn.) 9 Part, 3 parts of Herba Ephedrae (Ephedra sinica Stapf), 6 parts of Semen Armeniacae Amarum (Amygdalus Communis Vas), Rhizoma Curcumae (Curcuma Zedoaria (Christm.) Rosc) 9 parts, 9 parts of Radix Angelicae Sinensis (Angelica sinensis), Semen Persicae (semenpersicae, Peachseed) 9 parts, 9 parts of Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.), the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) 12 parts, 9 parts of Radix Glycyrrhizae (Radix Glycyrrhizae).

, according to traditional medicine and modern medical analysis, the property of medicine and pharmacological action are as follows for the Chinese herbal medicine of the present invention：

Cortex Moutan：Bitter in the mouth, pungent, it is slightly cold.GUIXIN, liver and kidney channel.Indication：Clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, warm febrile disease enter Blood system, send out speckle, tell nosebleed, calentura later stage hot Fu Yin distribute heat, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, fall and flutter Grieved, beriberoid pyretic arthralgia.

Radix Rehmanniae：Bitter in the mouth, trembles with fear, nontoxic.GUIXIN, liver and kidney channel.Indication：Clearing away heat and promoting production of body fluid, hemostasis, for hot blast impairment of YIN, Crimson tongue excessive thirst, spot dermexanthesis, haematemesis, epistaxis, laryngopharynx swelling and pain.

Radix Scrophulariae：Bitter in the mouth is salty, cold nature, nontoxic.Indication：Removing heat from blood YIN nourishing, eliminating fire and detoxication, fever excessive thirst, spontaneous sweating, Constipation, haematemesis nose bleeding, pharyngolaryngitis, pulmonary tuberculosis, for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, Tianjin hinder constipation, hectic fever due to yin labor is coughed, Conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.

Flos Lonicerae：Cold in nature, sweet in the mouth.Return lung, the heart, stomach.Indication：Heat-clearing and toxic substances removing, antiinflammatory, qi-restoratives treat wind, for various Febrile disease, such as fever of the body, dermexanthesis, a disease such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain.

Fructus Forsythiae：Cool in nature, bitter, it is slightly cold.Return lung, the heart, small intestine meridian.Indication：Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, for carbuncle, Scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warm is joined the army, hyperpyrexia excessive thirst, coma send out speckle, pyretic stranguria urine retention.

Radix Scutellariae：Hardship, trembles with fear.Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.Indication：Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, Antiabortive, blood pressure lowering, tells for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, hyperpyrexia excessive thirst, heat in blood Nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.

Herba Ephedrae：Pungent, slight bitter, temperature.Return lung, bladder warp.Indication：Diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema, are used for Anemofrigid cold, uncomfortable in chest breath with cough, edema due to wind pathogen edema, bronchial asthma.

Semen Armeniacae Amarum：Hardship, tepor, slightly poisonous.Indication：Relieving cough and asthma, loosening bowel to relieve constipation.

Rhizoma Curcumae：Bitter, pungent, temperature.Return liver, spleen channel.Indication：Blood-breaking, Xiao Ji Zhi Tong, for abdominal pain due to blood stasis, liver spleen Enlargement, trusted subordinate's distending pain, accumulation, women's blood stasis is through closing, traumatic injury are had a pain eating accumulation.

Radix Angelicae Sinensis：Sweet, acrid, warm.Return liver, the heart, spleen channel.Indication：Enrich blood, invigorate blood circulation, pain relieving, intestine moistening, for all cards of blood deficiency, Menoxenia, amenorrhea, dysmenorrhea and asthenia cold abdominalgia, blood stasis are had a pain, traumatic injury, arthralgia pain numbness, ulcer sores, blood deficiency dryness of the intestine just Secret.

Semen Persicae：Bitter, sweet, flat.GUIXIN, liver, large intestine channel.Indication：Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, lump for lump in the abdomen, Closed dysmenorrhea, stasis caused pain in puerperal etc..

Radix Codonopsis：Sweet, put down.Returns spleen, lung meridian.Indication：Invigorating the spleen and replenishing QI；For deficiency of vital energy deficiency, fatigue and weakness, nonproductive asthma The diseases such as rush, spleen eating less, the edema of the face, rush down prolapse of the anus for a long time.

The Rhizoma Atractylodis Macrocephalae：Bitter, sweet, temperature.Returns spleen, stomach.Indication：Invigorating the spleen and benefiting QI, eliminate dampness and have diuretic effect, hidroschesis, antiabortive, for insufficiency of the spleen Lack of appetite, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, edema, spontaneous perspiration, frequent fetal movement.

Radix Glycyrrhizae：Sweet, put down.GUIXIN, lung, spleen, stomach.Indication：Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, emergency are stopped Bitterly, coordinating the actions of various ingredients in a prescription, for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, four limbs contraction, carbuncle skin ulcer Poison, alleviate drug toxicity, strong.

Another object of the present invention is to providing above-mentioned Chinese prescription in preparation treatment mycoplasma pneumoniae pneumonia pharmaceutical preparation In application.

Preferably, mycoplasma pneumoniae pneumonia belongs to phlegm-heat closed lung type.

Sheerly prepared from traditional Chinese medicines forms the present invention, is a kind of Chinese medicine for oral administration, bright for treatment mycoplasma pneumoniae pneumonia effect Aobvious.

Brief description

Fig. 1 be the present invention Treated with Chinese Decoction mycoplasma pneumoniae pneumonia patient after patient's heating temp change curve.

Specific embodiment

In order to more fully understand and implement, further illustrate the present invention with reference to embodiment.If no special instructions, this Bright embodiment is only used for explaining the present invention, is not meant to limit protection scope of the present invention.

The preparation of embodiment 1 Chinese medicine extract

First, formula 1

The following raw material of Chinese medicine of precise：6 parts of Cortex Moutan (Paeonia suffruticosaAndr.), Radix Rehmanniae 9 parts of (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.etMey.), Radix Scrophulariae (Scrophularia Ningpoensis Hemsl.) 6 parts, 6 parts of Flos Lonicerae (Lonicera japonica Thunb.), Fructus Forsythiae (Forsythia Suspensa (Thunb.) Vahl) 6 parts, 6 parts of Radix Scutellariae (Scutellaria Linn.), Herba Ephedrae (Ephedra sinica Stapf) 1.5 parts, 6 parts of Semen Armeniacae Amarum (Amygdalus Communis Vas), Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc) 6 parts, 6 parts of Radix Angelicae Sinensis (Angelica sinensis), 6 parts of Semen Persicae (semenpersicae, peachseed), Radix Codonopsis 6 parts of (Codonopsis pilosula (Franch.) Nannf.), the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) 9 parts, 6 parts of Radix Glycyrrhizae (Radix Glycyrrhizae).Mixing is decocted in water for oral dose.

2nd, formula 2

The following raw material of Chinese medicine of precise：12 parts of Cortex Moutan (Paeonia suffruticosaAndr.), Radix Rehmanniae 15 parts of (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.), Radix Scrophulariae (Scrophularia Ningpoensis Hemsl.) 12 parts, 12 parts of Flos Lonicerae (Lonicera japonica Thunb.), Fructus Forsythiae (Forsythia Suspensa (Thunb.) Vahl) 9 parts, 12 parts of Radix Scutellariae (Scutellaria Linn.), Herba Ephedrae (Ephedra sinica Stapf) 3 parts, 9 parts of Semen Armeniacae Amarum (Amygdalus Communis Vas), Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc) 12 parts, 12 parts of Radix Angelicae Sinensis (Angelica sinensis), 12 parts of Semen Persicae (semenpersicae, peachseed), Radix Codonopsis 12 parts of (Codonopsis pilosula (Franch.) Nannf.), the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) 15 parts, 12 parts of Radix Glycyrrhizae (Radix Glycyrrhizae).Mixing is decocted in water for oral dose.

3rd, formula 3

The following raw material of Chinese medicine of precise：9 parts of Cortex Moutan (Paeonia suffruticosa Andr.), Radix Rehmanniae 15 parts of (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.), Radix Scrophulariae (Scrophularia Ningpoensis Hemsl.) 9 parts, 9 parts of Flos Lonicerae (Lonicera japonica Thunb.), Fructus Forsythiae (Forsythia Suspensa (Thunb.) Vahl) 6 parts, 9 parts of Radix Scutellariae (Scutellaria Linn.), Herba Ephedrae (Ephedra sinica Stapf) 3 parts, 6 parts of Semen Armeniacae Amarum (Amygdalus Communis Vas), Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc) 9 parts, 9 parts of Radix Angelicae Sinensis (Angelica sinensis), 9 parts of Semen Persicae (semenpersicae, peachseed), Radix Codonopsis 9 parts of (Codonopsis pilosula (Franch.) Nannf.), the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) 12 parts, 9 parts of Radix Glycyrrhizae (Radix Glycyrrhizae).Mixing is decocted in water for oral dose.

The examination of curative effect of embodiment 2 Chinese medicine extract

Below clinical efficacy detection is carried out to the Chinese medicine preparation of the formula preparation according to the embodiment of the present invention 1：

1. it is grouped situation：46 infants meeting phlegm-heat closed lung type mycoplasma pneumoniae pneumonia diagnostic criteria are randomly divided into and control Treatment group and matched group, treatment group adds Chinese medicine preparation Combined Treatment using Western medicine, and matched group is processed using Western medicine merely, wherein, controls Treatment group 23, matched group 23.

2. therapeutic administratp method and the course for the treatment of

Treatment group gives dead point Azithromycin 7 days, oral relieving cough and resolving phlegm Western medicine；Treatment group plus uses Chinese medicine on the basis for the treatment of group Preparation, treats 5 days altogether.

3. criterion of therapeutical effect

Comprehensive therapeutic effect evaluation criteria is issued with reference to State Administration of Traditional Chinese Medicine for 1994《Chinese medical disease diagnoses curative effect mark Quasi- TCM Pediatrics disease Standardization of diagnosis and curative effect》Interior pneumonia asthma cough efficacy assessment standard and《New Chinese medicine clinical research is instructed former Then》Formulate：

Recovery from illness：1. breathing recovers normal (frequency of respiration per minute is in range of normal value)；2. auscultation of lung tremble sound disappear；③ X-ray checks that pneumonia shade absorbs (two lung fields are clear)；4. Respiroviruses detection is negative；5. the minimizing of primary symptom integration is more than 90%.

Effective：1. breathing recovers normal (frequency of respiration per minute is in range of normal value)；2. auscultation of lung tremble sound disappear；③ X-ray checks pneumonia shade basic absorption (two lung fields no point lamellar confusing shadows)；4. Respiroviruses detection is negative；⑤ Primary symptom integration reduces ＜ 90%, is more than 67%.

Progressive：1. infant breathing return to normal (frequency of respiration per minute be less than corresponding age Upper Limit of Normal Value 10 Secondary)；2. auscultation of lung tremble sound reduce；3. x-ray checks that pulmonary shadow part absorbs；4. Respiroviruses detection is negative；5. primary symptom Integration reduces ＜ 67%, is more than 33%.

Invalid：Shape sign no significant change or increase, primary symptom integration reduces ＜ 33%.

Note：Disease integration reduces integration * 100% before percentage rate=(integrating after integration one treatment before treatment)/treatment

Primary symptom and time disease：

Primary symptom：Heat, cough, expectorant heap soil or fertilizer over and around the roots, tachypnea, flaring of nares, asthma, auscultation of lung, the full rabat of x-ray；

Secondary disease：Cold, dark purple, color, god, perspiration, thirsty, appetite, Nausea and vomiting, stool, urine, extremity, picture of the tongue, fingerprint.

Primary and secondary disease scale score standard：

Primary symptom：

Heating：37.2 DEG C 0 point of ＜；37.3～38.4 DEG C 2 points；38.5～39.4 DEG C 4 points；>=39.5 DEG C 6 points.

Cough：No cough 0 point；Even work, often coughs 2 points of monophone；Battle array is made, and often coughs 4 points of several sound；Hacking cough, often coughs many sound, and initiation is vomitted Tell, 6 points of impact work and rest.

Expectorant is stopped up：No 0 point of expectorant；There is expectorant sound, few 2 points of expectorant when in larynx；In larynx, expectorant is neighed, yellow 4 points of expectorant；In larynx, expectorant is shouted, the yellow amount of expectorant many 6 Point.

Tachypnea：Steadily, number of times is 0 point in corresponding age range of normal value for breathing；Exceed corresponding age Upper Limit of Normal Value little In equal to 10 beats/min, no flaring of nares, 2 points of three depressions sign；Exceed 11～20 beats/min of corresponding age Upper Limit of Normal Value, and/or interruption is breathed heavily Suppress, flaring of nares, 4 points of three depressions sign；Exceed corresponding age Upper Limit of Normal Value and be more than or equal to 21 beats/min, and/or persistently breathe heavily and suppress, flaring of nares, three Recessed levy 6 points.

Asthma, cyanosis：No, 0 point；Slightly breathe heavily, 2 points；Asthma is obvious, no 4 points of cyanosis；Asthma is notable, and cyanosis of the lips and nails needs oxygen uptake 6 points.

Auscultation of lung：Clear 0 point of respiratory murmur；Respiratory murmur reduce, coarse, or hear and in wet 2 points of sound of trembling；In the pulmonary of side, Carefully wet sound of trembling, and/or 4 points of sound of stridulating a little；In the pulmonary of both sides, carefully wet sound of trembling, and/or 6 points of sound of significantly stridulating.

The full rabat of x-ray：Clear 0 point of two lung fields；Enhanced lung markings, increase thick, disorderly 2 points；Point lamellar confusing shadows, limitation 4 points within 2 leaves；Point lamellar confusing shadows, 3 leaves and above 6 points.

With primary symptom integration as foundation, draft slight：8～16 points, moderate：17～26 points, severe：27～36 points.

Secondary disease：

Aversion to cold：0 point of nothing；1 point of aversion to wind；2 points of aversion to cold.

Cyanosis：0 point of nothing；1 point of lip dark purple；2 points of lips, refer to cyanosis.

Complexion：0 point normal；1 point of few China；2 partial tides are red, light white.

Spirit：0 point normal；1 point of agitation；2 points of spiritlessness and weakness.

Perspire：0 point normal；1 point of slight perspiration；The wet clothing of 2 points of hyperhidrosis.

Thirsty：0 point of nothing；1 point slightly thirsty；2 points of thirsty polydipsia.

Appetite：0 point normal；1 point of poor appetite；2 points of foods of not pursuing progress.

Nausea and vomiting：0 point of nothing；1 point of nausea；2 points of nausea and vomiting.

Stool：0 point normal；1 point of dry stool；2 points of stool are dilute.

Urine：0 point normal；1 point of Huang is few.

Extremity：0 point normal；Owe temperature for 1 point；2 points cool.

Body of the tongue：0 point normal；1 sub-prime is red；2 sub-primes are light red.

Tongue fur：0 point thin white；1 point of BOHUANG；2 points of yellow greasies；3 potted flower strippings.

Pulse condition (fingerprint)：0 point floating tight (red)；1 point of floating number (purple)；2 points of sliding numbers (purple stagnant)；3 points thin (light).

4. clinical treatment outcome

As shown in table 1, through t check analyses, difference no counts the integration of matched group and treatment group symptom, sign before the treatment Learn meaning (P ＞ 0.05) and there is comparability.

Front each group tcm symptom treated by table 1, somatic feature score compares

Before and after 4.1 each group treatments, symptom, sign total mark improve situation, are shown in Table 2, table 3：

Primary symptom, secondary disease integral contrast before and after table 2 matched group (n=23) treatment

Primary symptom, secondary disease integral contrast before and after table 3 treatment group (n=23) treatment

Statistical analysis understand, before and after treatment of control group, symptom and sign total mark has notable difference, and matched group is to clinical condition Shape sign is improved obvious curative effects (P ＜ 0.001).

Statistical analysis understand, before and after treatment group's treatment, symptom and sign total mark has notable difference, and treatment group is to clinical condition Shape sign is improved obvious curative effects (P ＜ 0.001).

Before and after 4.2 each group treatments, integration differential compares, and is shown in Table 4：

Table 4 treatment group is compared with integration differential before and after treatment of control group

Statistical analysis understand, variant for the improvement of clinical symptoms before and after two groups of treatments, treatment group exists compared with matched group Improve Clinical symptom and sign aspect and become apparent from (P ＜ 0.05).

Before and after 4.3 treatment of control group, symptom and sign improves situation, is shown in Table 5：

After table 5 treatment of control group, symptom, sign improve situation (example)

Understand through above analysis, after treatment, heating, cough and tachypnea symptom have apparent improvement to matched group (P ＜ 0.01), illustrates that matched group medicine has obvious curative effect in terms of improving heating, cough and tachypnea.

Before and after the treatment of 4.4 treatment groups, symptom and sign improves situation, is shown in Table 6：

After the treatment of table 6 treatment group, symptom, sign improve situation (example)

Analyzed from above, after treatment, in addition to auscultation of lung, symptom, sign all have clear improvement for treatment group.

Before and after 4.5 matched groups are treated with treatment group, primary symptom improves situation, is shown in Table 7：

Table 7 treatment group is compared with primary symptom integration differential before and after treatment of control group

Note：* P ＜ 0.05

Analyzed from above, relatively there are notable difference, P ＜ 0.05 in treatment group compared with matched group in terms of improving expectorant harmony, has Statistical significance；In terms of the improvement of heating, treatment group is better than matched group, but has no statistical significance, sees Fig. 1.

Above content is to further describe it is impossible to assert with reference to specific preferred implementation is made for the present invention Being embodied as of the present invention is confined to these explanations.For general technical staff of the technical field of the invention, On the premise of present inventive concept, some simple deduction or replace can also be made, all should be considered as belonging to the present invention's Protection domain.

Claims (4)

1. a kind of Chinese prescription treating mycoplasma pneumoniae pneumonia is it is characterised in that described Chinese prescription is by following mass parts Raw material of Chinese medicine is formulated：Cortex Moutan (Paeonia suffruticosa Andr.) 6-12 part, Radix Rehmanniae (Rehmannia Glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.) 9-15 part, Radix Scrophulariae (Scrophularia Ningpoensis Hemsl.) 6-12 part, Flos Lonicerae (Lonicera japonica Thunb.) 6-12 part, Fructus Forsythiae (Forsythia suspensa (Thunb.) Vahl) 6-9 part, Radix Scutellariae (Scutellaria Linn.) 6-12 part, Herba Ephedrae (Ephedra sinica Stapf) 1.5-3 part, Semen Armeniacae Amarum (Amygdalus Communis Vas) 6-9 part, Rhizoma Curcumae (Curcuma Zedoaria (Christm.) Rosc) 6-12 part, Radix Angelicae Sinensis (Angelica sinensis) 6-12 part, Semen Persicae (semenpersicae, peachseed) 6-12 part, Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.) 6-12 Part, the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) 9-15 part, Radix Glycyrrhizae (Radix Glycyrrhizae) 6- 12 parts.

2. Chinese prescription according to claim 1 is it is characterised in that described Chinese prescription is former by the Chinese medicine of following mass parts Material is formulated：9 parts of Cortex Moutan (Paeonia suffruticosa Andr.), Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.) 15 parts, Radix Scrophulariae (Scrophularia ningpoensis Hemsl.) 9 Part, 9 parts of Flos Lonicerae (Lonicera japonica Thunb.), Fructus Forsythiae (Forsythia suspensa (Thunb.) Vahl) 6 Part, 9 parts of Radix Scutellariae (Scutellaria Linn.), 3 parts of Herba Ephedrae (Ephedra sinica Stapf), Semen Armeniacae Amarum (Amygdalus Communis Vas) 6 parts, 9 parts of Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc), Radix Angelicae Sinensis (Angelica Sinensis) 9 parts, 9 parts of Semen Persicae (semenpersicae, peachseed), Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.) 9 parts, 12 parts of the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae), Radix Glycyrrhizae (Radix Glycyrrhizae) 9 parts.

3. application in preparation treatment mycoplasma pneumoniae pneumonia pharmaceutical preparation for the Chinese prescription described in claim 1.

4. application according to claim 3 is it is characterised in that described mycoplasma pneumoniae pneumonia belongs to phlegm-heat closed lung type.