CN104013905A - Traditional Chinese medicine formula for treating mycoplasmal pneumonia and application thereof - Google Patents
Traditional Chinese medicine formula for treating mycoplasmal pneumonia and application thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine formula for treating mycoplasmal pneumonia. The traditional Chinese medicine formula is prepared from the following traditional Chinese medicine raw materials: 6-12 parts of the root bark of the peony tree, 9-15 parts of radix rehmanniae recen, 6-12 parts of radix scrophulariae, 6-12 parts of honeysuckle flower, 6-9 parts of fructus forsythiae, 6-12 parts of scutellaria baicalensis, 1.5-3 parts of ephedra, 6-9 parts of almond, 6-12 parts of curcuma zedoary, 6-12 parts of Chinese angelica, 6-12 parts of peach kernel, 6-12 parts of codonopsis pilosula, 9-15 parts of bighead atractylodes rhizome and 6-12 parts of liquorice. The traditional Chinese medicine formula is reasonable in compatibility of medicines, convenient to process and low in cost, does not have toxic or side effect and has an obvious effect of treating the mycoplasmal pneumonia.
Description
Technical field
The invention belongs to modern Chinese traditional medicine field, be specifically related to a kind of the treat Chinese prescription of mycoplasma pneumoniae pneumonia and the application in the pharmaceutical preparation of preparation treatment mycoplasma pneumoniae pneumonia thereof.
Background technology
Mycoplasma pneumoniae pneumonia is the pneumonia being caused by mycoplasma pneumoniae, once claims primary atypical pneumonia.Be apt to occur in child or teenager, account for 15%～30% of pneumonia sum, popular year can be up to 40%～60%.Mycoplasma pneumoniae pneumonia onset is slow, approximately 2～3 weeks incubation periods, the sick first general malaise that has, weak, headache.Within 2～3 days, occur afterwards that heating body temperature often reaches 39 DEG C of left and right, sustainable 1～3 week, can be with pharyngalgia and muscular soreness.Cough for the outstanding symptom of primary disease,, in 2～3 days after being ill s, be generally just dry cough, after transfer intractable play to and cough, often have sticky sputum idol to be with the blood streak, minority case can the apasm of coughing of similar pertussis sample.Sustainable 1～4 week.How not obvious physical signs of lung is, even completely without.Dry, moist rales pleasure that minority can be heard.But polylith disappears, therefore sign and play are coughed and the clinical manifestation such as heating is inconsistent, be one of primary disease feature.Infant onset is anxious, and the course of disease is long, and the state of an illness is heavier, shows as dyspnea, to breathe heavily the sound of suppressing, stridulate comparatively outstanding, and pulmonary's rale is more than older youngster.Part infant child can suffer from hemolytic anemia, meningitis, myocarditis, groan, the Green-lungs such as sharp syndrome are showed outward.
The suitable antibacterials of early application can mitigation symptoms and are shortened the course of disease, and Macrolide antibacterials be first-selection, as erythromycin, Roxithromycin and azithromycin.Fluoroquinolones is as levofloxacin, Gatifloxacin and Moxifloxacin etc., and Tetracyclines is also for the treatment of mycoplasma pneumoniae pneumonia.General 2～3 weeks of the course for the treatment of.Use western medicine mycoplasma pneumoniae pneumonia not only treatment time long, and side effect is strong, affects child's growth, therefore finds successful, short treating period and the medicine having no side effect are problem demanding prompt solutions.From traditional medicine, find active active drug strong, that have no side effect and become the new way addressing this problem.
Summary of the invention
The object of the present invention is to provide a kind of effect remarkable, have no side effect, medication is convenient, the Chinese prescription for the treatment of mycoplasma pneumoniae pneumonia with low cost, and for realizing above object, the technical solution used in the present invention is:
A Chinese prescription for the treatment of mycoplasma pneumoniae pneumonia, is characterized in that, described Chinese prescription is formulated by the raw material of Chinese medicine of following mass parts: Cortex Moutan (Paeonia suffruticosaAndr.) 6-12 part, Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.) 9-15 part, Radix Scrophulariae (Scrophularia ningpoensis Hemsl.) 6-12 part, Flos Lonicerae (Lonicera japonica Thunb.) 6-12 part, Fructus Forsythiae (Forsythia suspensa (Thunb.) Vahl) 6-9 part, Radix Scutellariae (Scutellaria Linn.) 6-12 part, Herba Ephedrae (Ephedra sinica Stapf) 1.5-3 part, Semen Armeniacae Amarum (Amygdalus Communis Vas) 6-9 part, Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc) 6-12 part, Radix Angelicae Sinensis (Angelica sinensis) 6-12 part, Semen Persicae (semenpersicae, peachseed) 6-12 part, Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.) 6-12 part, the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) 9-15 part, Radix Glycyrrhizae (Radix Glycyrrhizae) 6-12 part.
Preferably, Chinese prescription of the present invention is formulated by the raw material of Chinese medicine of following mass parts: 9 parts of Cortex Moutans (Paeonia suffruticosa Andr.), 15 parts of Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.), 9 parts of Radix Scrophulariae (Scrophularia ningpoensis Hemsl.), 9 parts of Flos Lonicerae (Lonicera japonica Thunb.), 6 parts of Fructus Forsythiaes (Forsythia suspensa (Thunb.) Vahl), 9 parts of Radix Scutellariaes (Scutellaria Linn.), 3 parts, Herba Ephedrae (Ephedra sinica Stapf), 6 parts, Semen Armeniacae Amarum (Amygdalus Communis Vas), 9 parts of Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc), 9 parts of Radix Angelicae Sinensis (Angelica sinensis), 9 parts, Semen Persicae (semenpersicae, peachseed), 9 parts of Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.), 12 parts of the Rhizoma Atractylodis Macrocephalaes (Rhizoma Atractylodis Macrocephalae), 9 parts, Radix Glycyrrhizae (Radix Glycyrrhizae).
Chinese herbal medicine of the present invention is according to traditional medicine and modern medicine analysis, and the property of medicine and pharmacological action are as follows:
Cortex Moutan: bitter in the mouth, pungent, is slightly cold.GUIXIN, liver, kidney channel.Function cures mainly: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, hot Fu Yin of calentura later stage divides heating, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, falls and flutter the pain of injury, rheumatism pyretic arthralgia.
Radix Rehmanniae: bitter in the mouth, cold, nontoxic.GUIXIN, liver, kidney channel.Function cures mainly: clearing away heat and promoting production of body fluid, hemostasis, and for hot blast impairment of YIN, crimson tongue excessive thirst, a speckle dermexanthesis, haematemesis, epistaxis, laryngopharynx swelling and pain.
Radix Scrophulariae: bitter in the mouth is salty, cold nature is nontoxic.Function cures mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication, fever excessive thirst, spontaneous sweating, constipation, haematemesis nose bleeding, pharyngolaryngitis, pulmonary tuberculosis, hinder constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, Tianjin.
Flos Lonicerae: cold in nature, sweet in the mouth.Return lung, the heart, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency are treated wind, for various febrile diseases, as diseases such as fever of the body, dermexanthesis, a speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain.
Fructus Forsythiae: cool in nature, bitter, be slightly cold.Return lung, the heart, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma send out speckle, pyretic stranguria urine retention.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering, tell nosebleed, carbuncle sore tumefacting virus, frequent fetal movement for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood.
Herba Ephedrae: pungent, micro-hardship, temperature.Return lung, urinary bladder channel.Function cures mainly: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema, for anemofrigid cold, uncomfortable in chestly breath with cough, edema due to wind pathogen edema, bronchial asthma.
Semen Armeniacae Amarum: hardship, tepor, slightly poisonous.Function cures mainly: relieving cough and asthma, loosening bowel to relieve constipation.
Rhizoma Curcumae: bitter, pungent, temperature.Return liver, spleen channel.Function cures mainly: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving, for abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, gather, women's blood stasis amenorrhea, traumatic injury are had a pain eating accumulation.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Function cures mainly: enrich blood, invigorate blood circulation, pain relieving, intestine moistening, for all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea and asthenia cold abdominalgia, blood stasis have a pain, traumatic injury, arthralgia pain numbness, ulcer sores, the constipation of blood deficiency dryness of the intestine.
Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, and for lump in the abdomen caking, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.
Radix Codonopsis: sweet, flat.Return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI; For diseases such as deficiency of vital energy deficiency, fatigue and weakness, dyspnea with rapid breath, insufficiency of the spleen lack of appetite, the edema of the face, chronic diarrhea proctoptosis.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Function cures mainly: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive, for insufficiency of the spleen lack of appetite, abdominal distention have loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, and for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Another object of the present invention is to provide the application of above-mentioned Chinese prescription in the pharmaceutical preparation of preparation treatment mycoplasma pneumoniae pneumonia.
Preferably, mycoplasma pneumoniae pneumonia belongs to phlegm-heat closed lung type.
The present invention sheerly prepared from traditional Chinese medicines forms, and is a kind of Chinese medicine for oral administration, for treatment mycoplasma pneumoniae pneumonia successful.
brief description of the drawings
Fig. 1 is the change curve of patient's heating temp after Treated with Chinese Decoction mycoplasma pneumoniae pneumonia patient of the present invention.
Detailed description of the invention
In order to understand better and to implement, further illustrate the present invention below in conjunction with embodiment.If no special instructions, embodiments of the invention are only for explaining the present invention, and do not mean that restriction protection scope of the present invention.
The preparation of embodiment 1 Chinese medicine extract
One, formula 1
Accurately weigh following raw material of Chinese medicine: 6 parts of Cortex Moutans (Paeonia suffruticosaAndr.), 9 parts of Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.etMey.), 6 parts of Radix Scrophulariae (Scrophularia ningpoensis Hemsl.), 6 parts of Flos Lonicerae (Lonicera japonica Thunb.), 6 parts of Fructus Forsythiaes (Forsythia suspensa (Thunb.) Vahl), 6 parts of Radix Scutellariaes (Scutellaria Linn.), 1.5 parts, Herba Ephedrae (Ephedra sinica Stapf), 6 parts, Semen Armeniacae Amarum (Amygdalus Communis Vas), 6 parts of Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc), 6 parts of Radix Angelicae Sinensis (Angelica sinensis), 6 parts, Semen Persicae (semenpersicae, peachseed), 6 parts of Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.), 9 parts of the Rhizoma Atractylodis Macrocephalaes (Rhizoma Atractylodis Macrocephalae), 6 parts, Radix Glycyrrhizae (Radix Glycyrrhizae).Mixing water decoction.
Two, formula 2
Accurately weigh following raw material of Chinese medicine: 12 parts of Cortex Moutans (Paeonia suffruticosaAndr.), 15 parts of Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.), 12 parts of Radix Scrophulariae (Scrophularia ningpoensis Hemsl.), 12 parts of Flos Lonicerae (Lonicera japonica Thunb.), 9 parts of Fructus Forsythiaes (Forsythia suspensa (Thunb.) Vahl), 12 parts of Radix Scutellariaes (Scutellaria Linn.), 3 parts, Herba Ephedrae (Ephedra sinica Stapf), 9 parts, Semen Armeniacae Amarum (Amygdalus Communis Vas), 12 parts of Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc), 12 parts of Radix Angelicae Sinensis (Angelica sinensis), 12 parts, Semen Persicae (semenpersicae, peachseed), 12 parts of Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.), 15 parts of the Rhizoma Atractylodis Macrocephalaes (Rhizoma Atractylodis Macrocephalae), 12 parts, Radix Glycyrrhizae (Radix Glycyrrhizae).Mixing water decoction.
Three, formula 3
Accurately weigh following raw material of Chinese medicine: 9 parts of Cortex Moutans (Paeonia suffruticosa Andr.), 15 parts of Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.), 9 parts of Radix Scrophulariae (Scrophularia ningpoensis Hemsl.), 9 parts of Flos Lonicerae (Lonicera japonica Thunb.), 6 parts of Fructus Forsythiaes (Forsythia suspensa (Thunb.) Vahl), 9 parts of Radix Scutellariaes (Scutellaria Linn.), 3 parts, Herba Ephedrae (Ephedra sinica Stapf), 6 parts, Semen Armeniacae Amarum (Amygdalus Communis Vas), 9 parts of Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc), 9 parts of Radix Angelicae Sinensis (Angelica sinensis), 9 parts, Semen Persicae (semenpersicae, peachseed), 9 parts of Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.), 12 parts of the Rhizoma Atractylodis Macrocephalaes (Rhizoma Atractylodis Macrocephalae), 9 parts, Radix Glycyrrhizae (Radix Glycyrrhizae).Mixing water decoction.
The examination of curative effect of embodiment 2 Chinese medicine extract
The Chinese medicine preparation of preparing according to the formula of the embodiment of the present invention 1 is carried out to clinical efficacy detection below:
1. grouping situation: the 46 routine infants that meet the diagnostic criteria of phlegm-heat closed lung type mycoplasma pneumoniae pneumonia are divided into treatment group and matched group at random, treatment group is used Western medicine to add Chinese medicine preparation Combined Treatment, and matched group uses merely Western medicine processing, wherein, treatment group 23 examples, matched group 23 examples.
2. treatment medication and the course for the treatment of
Processed group is given dead point azithromycin 7 days, oral relieving cough and resolving phlegm Western medicine; Treatment group adds with Chinese medicine preparation on processed group basis, treats altogether 5 days.
3. criterion of therapeutical effect
" traditional Chinese medical science disease Standardization of diagnosis and curative effect TCM Pediatrics disease Standardization of diagnosis and curative effect " interior pneumonia asthma that comprehensive therapeutic effect evaluation criteria is issued with reference to State Administration of Traditional Chinese Medicine 1994 cough efficacy assessment standard and " new Chinese medicine guideline of clinical investigations " formulation:
Recovery from illness: 1. breathe and recover normal (frequency of respiration per minute is in range of normal value); 2. auscultation of lung tremble sound disappear; 3. x-ray checks that pneumonia shade absorbs (two lung fields are clear); 4. Respirovirus is learned and is detected feminine gender; 5. the minimizing of primary symptom integration is greater than 90%.
Effective: 1. to breathe and recover normal (frequency of respiration per minute is in range of normal value); 2. auscultation of lung tremble sound disappear; 3. x-ray checks pneumonia shade basic absorption (two lung fields are without the fuzzy shade of point lamellar); 4. Respirovirus detects negative; 5. primary symptom integration reduces < 90%, is greater than 67%.
Progressive: 1. infant is breathed basic recover normal (frequency of respiration per minute is no more than corresponding age Upper Limit of Normal Value 10 times); 2. auscultation of lung tremble sound reduce; 3. x-ray checks that pulmonary shadow part absorbs; 4. Respirovirus detects negative; 5. primary symptom integration reduces < 67%, is greater than 33%.
Invalid: shape sign is without significant change or increase the weight of primary symptom integration minimizing < 33%.
Note: disease integration reduces percentage rate=(the rear integration of integration one treatment before treating) front integration * 100% of/treatment
Primary symptom and time disease:
Primary symptom: heat, cough, expectorant heap soil or fertilizer over and around the roots, tachypnea, flaring of nares, asthma, auscultation of lung, the full breast sheet of x-ray;
Inferior disease: cold, dark purple, color, god, perspiration, thirsty, appetite, feel sick, vomiting, stool, urine, extremity, picture of the tongue, fingerprint.
Primary and secondary disease scale standards of grading:
Primary symptom:
Heating: 37.2 DEG C 0 point of <; 37.3～38.4 DEG C 2 points; 38.5～39.4 DEG C 4 points; >=39.5 DEG C 6 points.
Cough: without 0 point of cough; Even work, often coughs 2 points of monophones; Battle array is done, and often coughs 4 points of several sound; Hacking cough, often coughs many sound, causes vomiting, 6 points of impact work and rests.
Expectorant is stopped up: without 0 point, expectorant; In larynx time, there is expectorant sound, 2 points, few expectorant; In larynx, expectorant is neighed, yellow 4 points of expectorant; In larynx, expectorant is shouted, many 6 points of the yellow amount of expectorant.
Tachypnea: breathe steadily number of times in corresponding age range of normal value 0 point; Exceed corresponding age Upper Limit of Normal Value and be less than or equal to 10 beats/min, without flaring of nares, 2 points of three depressions signs; Exceed 11～20 beats/min of corresponding age Upper Limit of Normal Values, and/or be interrupted to breathe heavily and suppress, flaring of nares, 4 points of three depressions signs; Exceed corresponding age Upper Limit of Normal Value and be more than or equal to 21 beats/min, and/or continue to breathe heavily and suppress, flaring of nares, 6 points of three depressions signs.
Asthma, cyanosis: nothing, 0 point; Slightly breathe heavily 2 points; Asthma is obvious, without 4 points of cyanosis; Significantly, cyanosis of the lips and nails, needs 6 points of oxygen uptakes in asthma.
Auscultation of lung: clear 0 point of respiratory murmur; Respiratory murmur reduces, coarse, or hear and in wet 2 points of the sounds of trembling; In one side pulmonary, the thin wet sound of trembling, and/or a little 4 points of sound of stridulating; In the pulmonary of both sides, the thin wet sound of trembling, and/or 6 points of sounds of significantly stridulating.
The full rabat of x-ray: clear 0 point of two lung fields; Enhanced lung markings, increase thick, disorderly 2 points; The fuzzy shade of point lamellar, is confined to 2 leaves with interior 4 points; The fuzzy shade of point lamellar, 3 leaves and above 6 points.
Taking primary symptom integration as foundation, draft slight: 8～16 points, moderate: 17～26 points, severe: 27～36 points.
Inferior disease:
Aversion to cold: 0 point of nothing; 1 point of aversion to wind; 2 points of aversion to cold.
Cyanosis: 0 point of nothing; 1 point of lip dark purple; 2 points of lips, refer to cyanosis.
Complexion: 0 point normal; 1 point of few China; 2 points of flushing, light white.
Spirit: 0 point normal; 1 point of agitation; 2 points of spiritlessness and weakness.
Perspire: 0 point normal; 1 point of slight perspiration; 2 points of wet clothing of hyperhidrosis.
Thirsty: 0 point of nothing; 1 point slightly thirsty; 2 points of thirsty polydipsia.
Appetite: 0 point normal; 1 point of poor appetite; 2 points of foods of not pursuing progress.
Nausea and vomiting: 0 point of nothing; Feel sick for 1 point; 2 points of nausea and vomiting.
Stool: 0 point normal; 1 point of dry stool; 2 points of stool are rare.
Urine: 0 point normal; 1 point of Huang is few.
Extremity: 0 point normal; Owe temperature for 1 point; 2 points cool.
Body of the tongue: 0 point normal; 1 sub-prime is red; 2 sub-primes are light red.
Tongue fur: 0 point thin white; 1 point of BOHUANG; 2 points of Huangs are greasy; 3 potted flower strippings.
Pulse condition (fingerprint): 0 point floating tight (red); 1 point of floating number (purple); 2 points of sliding numbers (purple stagnant); 3 points thin (light).
4. clinical treatment result
As shown in table 1, the integration of matched group and treatment group symptom, sign before treatment is through t check analysis, and difference not statistically significant (P > 0.05) has comparability.
Each group tcm symptom, somatic feature score comparison before table 1 treatment
Before and after 4.1 each group treatments, symptoms, sign total mark are improved situations, in table 2, table 3:
Primary symptom, inferior disease integral contrast before and after table 2 matched group (n=23) treatment
Primary symptom, inferior disease integral contrast before and after table 3 treatment group (n=23) treatment
Statistical analysis is known, and before and after treatment of control group, symptom and sign total mark has notable difference, and matched group improves and has obvious curative effects (P < 0.001) clinical symptoms sign.
Statistical analysis is known, and before and after treatment group treatment, symptom and sign total mark has notable difference, and treatment group is improved and had obvious curative effects (P < 0.001) clinical symptoms sign.
Integration differential comparisons before and after 4.2 each group treatments, in table 4:
Integration differential comparison before and after table 4 treatment group and treatment of control group
Statistical analysis is known, variant for the improvement of clinical symptoms before and after two groups of treatments, and treatment group is being improved aspect clinical symptoms sign more obviously (P < 0.05) compared with matched group.
4.3 symptom and signs before and after treatment of control group improve situations, in table 5:
After table 5 treatment of control group, symptom, sign are improved situation (example)
Analyze knownly through above, matched group is after treatment, and heating, cough and tachypnea symptom have had improving clearly (P < 0.01), illustrates that matched group medicine has obvious curative effect improving aspect heating, cough and tachypnea.
Before and after 4.4 treatment groups treatments, symptom and signs improve situations, in table 6:
After the treatment of table 6 treatment group, symptom, sign are improved situation (example)
From analyzing above, treatment group is after treatment, and except auscultation of lung, symptom, sign all have clear improvement.
Before and after the treatment of 4.5 matched groups and treatment group, primary symptom is improved situation, in table 7:
Primary symptom integration differential comparison before and after table 7 treatment group and treatment of control group
Note: * P < 0.05
From analyzing above, treatment group relatively has notable difference compared with matched group improving aspect expectorant harmony, and P < 0.05, has statistical significance; Aspect the improving of heating, treatment group is better than matched group, but has no statistical significance, sees Fig. 1.
Above content is in conjunction with concrete preferred implementation further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace, all should be considered as belonging to protection scope of the present invention.
Claims (4)
1. a Chinese prescription for the treatment of mycoplasma pneumoniae pneumonia, is characterized in that, described Chinese prescription is formulated by the raw material of Chinese medicine of following mass parts: Cortex Moutan (Paeonia suffruticosa Andr.) 6-12 part, Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.) 9-15 part, Radix Scrophulariae (Scrophularia ningpoensis Hemsl.) 6-12 part, Flos Lonicerae (Lonicera japonica Thunb.) 6-12 part, Fructus Forsythiae (Forsythia suspensa (Thunb.) Vahl) 6-9 part, Radix Scutellariae (Scutellaria Linn.) 6-12 part, Herba Ephedrae (Ephedra sinica Stapf) 1.5-3 part, Semen Armeniacae Amarum (Amygdalus Communis Vas) 6-9 part, Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc) 6-12 part, Radix Angelicae Sinensis (Angelica sinensis) 6-12 part, Semen Persicae (semenpersicae, peachseed) 6-12 part, Radix Codonopsis (Codonopsispilosula (Franch.) Nannf.) 6-12 part, the Rhizoma Atractylodis Macrocephalae (Rhizoma Atractylodis Macrocephalae) 9-15 part, Radix Glycyrrhizae (Radix Glycyrrhizae) 6-12 part.
2. Chinese prescription according to claim 1, is characterized in that, described Chinese prescription is formulated by the raw material of Chinese medicine of following mass parts: 9 parts of Cortex Moutans (Paeonia suffruticosa Andr.), 15 parts of Radix Rehmanniae (Rehmannia glutinosa (Gaetn.) Libosch.ex Fisch.et Mey.), 9 parts of Radix Scrophulariae (Scrophularia ningpoensis Hemsl.), 9 parts of Flos Lonicerae (Lonicera japonica Thunb.), Fructus Forsythiae (Forsythia suspensaThunb.) Vahl) 6 parts, 9 parts of Radix Scutellariaes (Scutellaria Linn.), 3 parts, Herba Ephedrae (Ephedra sinica Stapf), 6 parts, Semen Armeniacae Amarum (Amygdalus Communis Vas), 9 parts of Rhizoma Curcumae (Curcuma zedoaria (Christm.) Rosc), 9 parts of Radix Angelicae Sinensis (Angelica sinensis), 9 parts, Semen Persicae (semenpersicae, peachseed), 9 parts of Radix Codonopsis (Codonopsis pilosula (Franch.) Nannf.), 12 parts of the Rhizoma Atractylodis Macrocephalaes (Rhizoma Atractylodis Macrocephalae), 9 parts, Radix Glycyrrhizae (Radix Glycyrrhizae).
3. the application of Chinese prescription claimed in claim 1 in the pharmaceutical preparation of preparation treatment mycoplasma pneumoniae pneumonia.
4. application according to claim 2, is characterized in that, described mycoplasma pneumoniae pneumonia belongs to phlegm-heat closed lung type.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104474523A (en) * | 2015-01-09 | 2015-04-01 | 江秀爱 | Medicine for treating phlegm-heat accumulated-in-lung type mycoplasma pneumonia and preparation method thereof |
| CN105434974A (en) * | 2016-01-29 | 2016-03-30 | 山东电力中心医院 | Traditional Chinese medicine composition for treating mycoplasma pneumonia and preparation method |
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| CN104474523A (en) * | 2015-01-09 | 2015-04-01 | 江秀爱 | Medicine for treating phlegm-heat accumulated-in-lung type mycoplasma pneumonia and preparation method thereof |
| CN105434974A (en) * | 2016-01-29 | 2016-03-30 | 山东电力中心医院 | Traditional Chinese medicine composition for treating mycoplasma pneumonia and preparation method |
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| CN104013905B (en) | 2017-02-15 |
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