CN101711830B - Traditional Chinese medicine composition for treating chronic bronchitis - Google Patents
Traditional Chinese medicine composition for treating chronic bronchitis Download PDFInfo
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- CN101711830B CN101711830B CN2009102310302A CN200910231030A CN101711830B CN 101711830 B CN101711830 B CN 101711830B CN 2009102310302 A CN2009102310302 A CN 2009102310302A CN 200910231030 A CN200910231030 A CN 200910231030A CN 101711830 B CN101711830 B CN 101711830B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating chronic bronchitis, which is characterized by being prepared from the following raw materials of medicines in parts by weight: 20 of astragalus root, 15 of radix sileris, 20 of white atractylodes rhizome, 10 of honeysuckle, 10 of weeping forsythia, 15 of dahurian angelica root, 5 of Chinese ephedra, 15 of radix glehniae, 5 of tendrilleaf fritillary, 30 of oldenlandia diffusa, 20 of cordate houttuynia, 10 of dahurian rhododendron leaf, 15 of radix rehmanniae, 12 of yam, 5 of dogwood, 10 of herba epimedii, 8 of radix codonopsis pilosulae and 5 of licorice. The invention takes the natural traditional Chinese medicines as the raw materials and has small toxic or side effect, definite curative effect and little possibility of relapse, and the total effective rate of treating the chronic bronchitis by the traditional Chinese medicine composition is 95.3%.
Description
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of chronic bronchitis.
Background technology
Chronic bronchitis is meant the chronic nonspecific inflammation of trachea, bronchial mucosa and surrounding tissue thereof.Clinically with cough, expectoration or with panting and the chronic process of outbreak repeatedly is a feature.If the state of an illness is slow progress, Chang Bingfa obstructive emphysema, even pulmonary hypertension, pulmonary heart disease.It is a kind of commonly encountered diseases, sees with the old people especially more.According to statistics, the old people prevalence of China more than 50 years old can be up to about 15%.The cause of disease of chronic bronchitis is also clear fully till now, thinks according to domestic and international investigation and research, and be the long-term synergistic result of multiple factor.Virus and the caused infection of antibacterial are the key factors of chronic bronchitis secondary infection and aggravation pathological development, the chronic stimulation of dust, atmospheric pollution, irritating smog, long-term smoking is a main diseases therefore, weather cold, irritated factor also are the inducements of morbidity.Abwehrkraft des Koepers weakens, and respiratory tract local defense function reduces, and is the endogenous cause of ill that causes chronic bronchitis.
The chronic bronchitis morbidity is slow, and the course of disease is longer, and outbreak increases the weight of gradually repeatedly.Cardinal symptom is cough, expectoration, pant or breathe hard, and to attach most importance at early morning or night, amount of expectoration increases especially.When concurrent emphysema,, engender dyspnea except that coughing, expectorant, breathing heavily etc. the symptom.Originally only tachypnea when work along with PD, is also felt during later tranquillization and being breathed hard.
At present clinically still can not effect a radical cure chronic bronchitis, also lack the ideal medicament and the effect method of treatment chronic bronchitis, most medicines recur easily, repeatedly outbreak.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of chronic bronchitis, this medication effect is good, and is difficult for recurrence.
Technical scheme of the present invention is: a kind of Chinese medicine composition for the treatment of chronic bronchitis, it is characterized in that, make: the Radix Astragali 20, Radix Saposhnikoviae 15, the Rhizoma Atractylodis Macrocephalae 20, Flos Lonicerae 10, Fructus Forsythiae 10, the Radix Angelicae Dahuricae 15, Herba Ephedrae 5, Radix Glehniae 15, Bulbus Fritillariae Cirrhosae 5, Herba Hedyotidis Diffusae 30, Herba Houttuyniae 20, Folium Rhododendri Daurici 10, Radix Rehmanniae 15, Rhizoma Dioscoreae 12, Fructus Corni 5, Herba Epimedii 10, Radix Codonopsis 8, Radix Glycyrrhizae 5 by following raw medicaments in portion by weight.
Collocation method: be decocted in water for oral dose, every day, potion was taken at twice.
The single-dose amount of Chinese medicine composition of the present invention is: the Radix Astragali 20 grams, Radix Saposhnikoviae 15 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Flos Lonicerae 10 grams, Fructus Forsythiae 10 grams, the Radix Angelicae Dahuricae 15 grams, Herba Ephedrae 5 grams, Radix Glehniae 15 grams, Bulbus Fritillariae Cirrhosae 5 grams, Herba Hedyotidis Diffusae 30 grams, Herba Houttuyniae 20 grams, Folium Rhododendri Daurici 10 grams, Radix Rehmanniae 15 grams, Rhizoma Dioscoreae 12 grams, Fructus Corni 5 grams, Herba Epimedii 10 grams, Radix Codonopsis 8 grams, Radix Glycyrrhizae 5 grams.
The treatment of chronic bronchitis should be adhered to the principle of " strengthening the body resistance ", promptly by the resistance against diseases of reinforcing body resistance with the enhancing human body, reaches the expeling pathogenic factor, thereby promotes the recovery of physiological function.The Radix Astragali, Radix Saposhnikoviae, Rhizoma Atractylodis Macrocephalae the body resistance strengthening and constitution consolidating among the we, Flos Lonicerae, Fructus Forsythiae, Herba Ephedrae, the Radix Angelicae Dahuricae, the Herba Houttuyniae cold expelling that induces sweat, Radix Glehniae, Herba Hedyotidis Diffusae, Bulbus Fritillariae Cirrhosae, Folium Rhododendri Daurici nourishing YIN and clearing away lung-heat, Radix Rehmanniae, Rhizoma Dioscoreae resolving phlegm and relieving asthma, Fructus Corni, Herba Epimedii, Radix Codonopsis invigorating the spleen and replenishing QI, the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, various medicines are collaborative mutually, reach the effect of curing chronic bronchitis jointly.
The pharmacological action of each Chinese medicine:
The Radix Astragali: sweet, warm.Return lung, spleen channel.Effect: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
Radix Saposhnikoviae: hot, sweet, temperature.Return bladder, liver, spleen channel.Function with cure mainly: inducing diaphoresis to dispel wind, win wet, relieving convulsion.Be used for headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Function with cure mainly: invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Flos Lonicerae: sweet, cold.Return lung, the heart, stomach warp.Function with cure mainly: heat-clearing and toxic substances removing, wind-heat dissipating.Be used for the carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating.
Fructus Forsythiae: hardship is slightly cold.Return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly: be used for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, the hyperpyrexia excessive thirst, coma is sent out speckle, the pyretic stranguria urine retention.
The Radix Angelicae Dahuricae: suffering, temperature.Return stomach, large intestine, lung meridian.Function with cure mainly: the wind dehumidifying of loosing, understand things pain-stopping, detumescence and apocenosis.Be used for headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Herba Ephedrae: hot, little hardship, temperature.Return lung, urinary bladder channel.Function with cure mainly: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Be used for anemofrigid cold, uncomfortable in chest breathing with cough, edema due to wind pathogen edema; Bronchial asthma.Honey Herba Ephedrae nourishing the lung to arrest cough.Be used to show disease more and separate asthma and cough.
Radix Glehniae: sweet, little hardship is slightly cold.Attach to the lung and stomach meridians.Function with cure mainly: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.Be used for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound is thirsty.
Bulbus Fritillariae Cirrhosae: bitter, sweet, be slightly cold.Return lung, heart channel.Function with cure mainly: clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.Be used for lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood.
Herba Hedyotidis Diffusae: heat clearing away, dampness removing, detoxifcation.Control dyspnea and cough due to lung-heat, tonsillitis.Pharyngolaryngitis, appendicitis, dysentery, urinary tract infection, jaundice, hepatitis, pelvic inflammatory disease, adnexitis, carbuncle furuncle, venom, tumor.Also can be used for alimentary tract cancer.
Herba Houttuyniae: suffering is slightly cold.Return lung meridian.Function with cure mainly: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.Be used for the lung abscess vomiting pus, the expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.
Folium Rhododendri Daurici: hot, bitter, temperature.Return lung, spleen channel.Function with cure mainly: cough-relieving, eliminate the phlegm.Be used for acute and chronic bronchitis.
Radix Rehmanniae: sweet, cold.GUIXIN, liver, kidney channel.Function with cure mainly: clearing away heat and cooling blood, yin nourishing is promoted the production of body fluid.Be used for calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.
Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Function with cure mainly: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.The Rhizoma Dioscoreae (parched with bran) spleen reinforcing is good for the stomach.Be used for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.
Fructus Corni: sour, puckery, tepor.Return liver, kidney channel.Function with cure mainly: liver and kidney tonifying, essence astringing and desertion stemming.Be used for vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, the profuse sweating collapse, interior-heat is quenched one's thirst.
Herba Epimedii: hot, sweet, temperature.Return liver, kidney channel.Function with cure mainly: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Be used for impotence and seminal emission, the muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Radix Codonopsis: sweet, flat.Return spleen, lung meridian.Function with cure mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Function with cure mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The invention has the beneficial effects as follows: the present invention is a raw material with natural Chinese medicine, and toxic and side effects is little, determined curative effect, and be difficult for recurrence, be 95.3% with traditional Chinese medicine composition for treating chronic bronchitis total effective rate of the present invention.
Further specify its beneficial effect below in conjunction with clinical data and model case
One, clinical observation
1. clinical data: be selected from the outpatient service that has complete data year May in May, 1998 to 2000 and inpatient totally 127 examples, be divided into treatment at random and organize 64 examples, matched group 63 examples.The treatment group age is 40-60 year, 52.3 years old mean age, course of disease 5-10, average 7.5 years, the matched group age is at 42-60 year, 52.8 years old mean age, course of disease 5-10, average 7.8 years, the age and the course of disease be through X 2 test, no statistically-significant difference (p＞0.05).
2. diagnostic criteria: (1) cough, expectoration or companion pant, annual morbidity 3 months, continuous 2 years or above person; (2) annual morbidity less than is 3 months, and has clear and definite objective determination also diagnosable according to (as X line, determination of respiratory function etc.) person; (3) can get rid of other hearts, lung disease (as pulmonary tuberculosis, asthma, bronchiectasis, pulmonary carcinoma, heart disease etc.) person.
3. Therapeutic Method: the treatment group is taken medicine of the present invention, is decocted in water for oral dose, and every day, potion was taken at twice, took 1 month; Matched group is taken CHUANFUKANG JIAONANG, and every day 3 times, a 2-4 grain was taken 1 month.
4. efficacy assessment standard: " disease of tcm diagnosis criterion of therapeutical effect " and the national chronic bronchitis clinical efficacy evaluation criteria formulated with reference to State Administration of Traditional Chinese Medicine: 1. clinic control: cough, expectorant, breathe heavily, cardinal symptom basic controlling such as inflammation, stable disease, no recidivist.2. produce effects: cough, expectorant, asthma shape and attack times minimizing; 3. effective: as to cough, expectorant, asthma shape and attack times minimizing; 4. invalid: as to cough, expectorant, asthma shape and attack times all do not have the changer.
5. therapeutic outcome: two groups of therapeutic outcomes are as shown in table 1:
Table 1 liang group cure rate synopsis
| Group | Example is inferior | Clinic control number/example | Produce effects number/example | Significant figure/example | Invalid number/example | Total effective rate (%) |
| The treatment group | 64 | 30 | 21 | 10 | 3 | 95.3 |
| Matched group | 63 | 15 | 18 | 13 | 17 | 73.0 |
Through X 2 test, two groups of effective percentage compare, and difference has highly significant (P＜0.001).
Two, model case:
Case 1: Zhao, woman, 55 years old.The emphysema medical history is year surplus in the of 20, cough, asthma are not healed all the year round, annual winter and flu postemphasis, hospitalization time and again is with oxygen uptake, antiinflammatory, relief of symptoms such as relieving asthma, once obey Chinese herbal medicine and do not have positive effect, all the year round with medicines such as aerosol, terbutalines in the hope of respite, very painful, take behind the medicine of the present invention that symptom alleviates greatly after 1 month, take after 3 months and thoroughly cure, do not have recurrence in 2 years.
Case 2: Lee, the man, 60 years old, the patient had following symptom before 10 years: cough, cough with asthma excessive phlegm, breast are born and to be felt oppressed, and must not put down for sleeping inly, and larynx sound is filtered, expectoration again and again, amount of expectoration reaches half bowl unexpectedly in two hours.Immediate cause work sweating, thin accidentally clothing sense is cold, so that cold and hot, cough, expectoration, all diseases of dyspnea with rapid and short breath are done together.The thin Mental fatigue of shape, face is edema slightly, and cough is breathed hard, sweating while acting.Took behind the medicine of the present invention 2 months, and took an evident turn for the better, cough and abundant expectoration phenomenon obviously alleviate, and it is normal that face recovers, and thoroughly cures after 3 months.
The specific embodiment
Embodiment 1:
Prescription: the Radix Astragali 20, Radix Saposhnikoviae 15, the Rhizoma Atractylodis Macrocephalae 20, Flos Lonicerae 10, Fructus Forsythiae 10, the Radix Angelicae Dahuricae 15, Herba Ephedrae 5, Radix Glehniae 15, Bulbus Fritillariae Cirrhosae 5, Herba Hedyotidis Diffusae 30, Herba Houttuyniae 20, Folium Rhododendri Daurici 10, Radix Rehmanniae 15, Rhizoma Dioscoreae 12, Fructus Corni 5, Herba Epimedii 10, Radix Codonopsis 8, Radix Glycyrrhizae 5.
Collocation method: be decocted in water for oral dose, every day, potion was taken at twice.
Claims (1)
1. Chinese medicine composition for the treatment of chronic bronchitis, it is characterized in that, make: the Radix Astragali 20, Radix Saposhnikoviae 15, the Rhizoma Atractylodis Macrocephalae 20, Flos Lonicerae 10, Fructus Forsythiae 10, the Radix Angelicae Dahuricae 15, Herba Ephedrae 5, Radix Glehniae 15, Bulbus Fritillariae Cirrhosae 5, Herba Hedyotidis Diffusae 30, Herba Houttuyniae 20, Folium Rhododendri Daurici 10, Radix Rehmanniae 15, Rhizoma Dioscoreae 12, Fructus Corni 5, Herba Epimedii 10, Radix Codonopsis 8, Radix Glycyrrhizae 5 by following raw medicaments in portion by weight.
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| CN102973833B (en) * | 2012-12-25 | 2014-08-13 | 丁金荣 | Pharmaceutical composition for treating bronchitis |
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| CN101095835B (en) * | 2007-07-16 | 2012-06-20 | 罗连珍 | Decoction medicine for treating yellow-sputum large-quantity type chronic bronchitis and method for preparing the same |
| CN103083597B (en) * | 2011-10-28 | 2014-11-26 | 北京六盛合医药科技有限公司 | Chronic bronchitis treatment drug composition and preparation method thereof |
| CN103142809A (en) * | 2013-03-15 | 2013-06-12 | 陈国光 | Herbal tea capable of improving immunological function and preparation technology thereof |
| CN103989762B (en) * | 2014-05-20 | 2015-07-29 | 扬子江药业集团四川海蓉药业有限公司 | Chinese medicine composition of internal organs relieving cough and resolving phlegm and preparation method thereof is rushed down in a kind of heat clearing away |
| CN104958430A (en) * | 2015-08-04 | 2015-10-07 | 青岛蓝盛洋医药生物科技有限责任公司 | Traditional Chinese medicinal composition for treating chronic trachitis and preparation method thereof |
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| CN1310002A (en) * | 2001-02-19 | 2001-08-29 | 孟庆云 | Combined Chinese and Western medicine for treating bronchial asthma |
| CN101028507A (en) * | 2007-02-26 | 2007-09-05 | 赵红霞 | Chinese-medicinal composition for treating asthma |
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