CN104013810A - Traditional Chinese medicine (TCM) composition for treating varicocele - Google Patents
Traditional Chinese medicine (TCM) composition for treating varicocele Download PDFInfo
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- CN104013810A CN104013810A CN201410296783.2A CN201410296783A CN104013810A CN 104013810 A CN104013810 A CN 104013810A CN 201410296783 A CN201410296783 A CN 201410296783A CN 104013810 A CN104013810 A CN 104013810A
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Abstract
The invention discloses a traditional Chinese medicine (TCM) composition for treating varicocele. The TCM composition is characterized by being prepared from the following TCM raw materials in parts by weight: 10-25 parts of herba epimedii, 10-25 parts of Chinese angelica, 10-30 parts of white paeony root, 10-30 parts of Sichuan lovage rhizome, 10-30 parts of turtle carapace, 10-30 parts of lychee seed, 10-30 parts of salvia miltiorrhiza, 10-20 parts of tortoise shell, 10-20 parts of deer-horn glue, 10-20 parts of prepared rhizome of rehmannia, 10-20 parts of rhizoma polygonati, 10-20 parts of morinda root and 10-20 parts of oriental waterplantain rhizome. The TCM composition has the advantages of exact curative effects, low treatment cost, simple and convenient preparation and taking methods, no side effects, low relapse rate after cure, and the like.
Description
Technical field:
The present invention relates to Chinese medicine technical field, particularly a kind of Chinese medicine composition for the treatment of varicocele.
Background technology:
Varicocele refers to that pampiniform plexus interior in spermatic cord is because of backflow obstruction, and the tortuous expansion, the elongation and tortuous that occur.Be between twenty and fifty common disease, refer to because spermatic vein blood stagnation causes the vasodilation of spermatic cord pampiniform plexus, tortuous and elongated.Primary disease is asymptomatic under normal circumstances, how in the time of routine physical examination, to find, or in the time of self-health check-up, finds scrotum Silent Neuritis Lumbricus shape agglomerate, or because sterilely find when medical.Some patient can be with symptoms such as falling inflation sense, dull pain, discomforts, and after station, walking, symptom can increase the weight of for a long time, after flat crouching, can alleviate or disappear.
At present, mainly take surgical resection or reparation, but it is large to exist wound for the treatment of primary disease, painful large, recovery time is long, and expense is high, and Postoperative recurrent rate is higher, and perform the operation may after the shortcoming such as recur.
Summary of the invention:
The present invention is exactly in order to make up deficiency of the prior art, for a kind for the treatment of for varicocele have that determined curative effect, medical expense are cheap, preparation and instructions of taking easy, and it is little to have no side effect, and controls the Chinese medicine composition that recurrence rate after healing is low.
The invention provides following technical scheme:
Treat a Chinese medicine composition for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Herba Epimedii 10-25 part, Radix Angelicae Sinensis 10-25 part, Radix Paeoniae Alba 10-30 part, Rhizoma Chuanxiong 10-30 part, Carapax Trionycis 10-30 part, Semen Litchi 10-30 part, Radix Salviae Miltiorrhizae 10-30 part, Carapax et Plastrum Testudinis 10-20 part, Colla cornus cervi 10-20 part, Radix Rehmanniae Preparata 10-20 part, Rhizoma Polygonati 10-20 part, Radix Morindae Officinalis 10-20 part, Rhizoma Alismatis 10-20 part.
Formula optimization is:
18 parts of Herba Epimedii, 15 parts of Radix Angelicae Sinensis, 15 parts of the Radix Paeoniae Albas, 15 parts of Rhizoma Chuanxiongs, 15 parts of Carapax Trionycis, 15 parts of Semen Litchis, 15 parts of Radix Salviae Miltiorrhizaes, 12 parts of Carapax et Plastrum Testudiniss, 12 parts of Colla cornus cervis, 12 parts, Radix Rehmanniae Preparata, 12 parts of Rhizoma Polygonatis, 12 parts of Radix Morindae Officinaliss, 12 parts of Rhizoma Alismatis.
Preparation method:
Get by weight ratio that after Carapax Trionycis, Carapax et Plastrum Testudinis, Colla cornus cervi mix, to be brewed into cream for subsequent use, other raw material is decocted after 3 times, filtering medicinal residues, be condensed into original volume 25% after add the ointment of making of Carapax Trionycis, Carapax et Plastrum Testudinis, Cornu Cervi, after fully stirring, be condensed into dry extract, be ground into after 400 order fine powders, add again typical additives in pharmaceutics, after sterilizing, can make various common formulations.
Take explanation:
Take medicine every day 3 times, morning, noon and afternoon one after each meal, each serving with containing 5 grams of crude drugs, one week is a course for the treatment of.
Form being described in detail as follows of each raw material of Chinese medicine of the present invention:
Herba Epimedii: and Herba Epimedii, acrid-sweet flavor is warm in nature, returns Liver and kidney warp.There is kidney-replenishing, bone and muscle strengthening, the effects such as wind-damp dispelling.Be usually used in impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; The diseases such as climacteric hypertension.In this product, contained Herba Epimedii total flavones glycosides not only can improve the function of mouse macrophage, and the fibrinolysis activity of the macrophage of promotion mice, improve the activity of plasminogen activator, obviously reduce the mortality rate of apoplexy susceptible type spontaneous hypertensive rat, and the rising icariin that can suppress its blood pressure has the effect that is subject to the voltage dependent form Ca++ passage (ROC) of actuated Ca++ passage (ROC) on blocking-up vascular smooth muscle, thereby blood vessel dilating, reduces blood pressure; Herba Epimedii total flavones reduces blood viscosity, suppress external thrombus forms, and is conducive to the elimination of blood stasis and prevents the generation of blood stasis, plays the combination that regulates whole and part.In addition, Herba Epimedii also there is antitussive, relieving asthma, eliminate the phlegm, ease pain, the effect such as calmness, local anaesthesia, antibacterial, antiinflammatory, antitumor.
Radix Angelicae Sinensis: warm in nature, hide sweet, pungent.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effects such as loosening bowel to relieve constipation.Be usually used in the diseases such as blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.This product has antithrombotic and forms, improve blood circulation, arrhythmia is had to protection, improve coronary circulation, antiinflammatory, analgesia, blood sugar lowering, reduce Acute Hypoxic Pulmonary Hypertension in Anesthetized, improve detection of glomeruli filtration function and reabsorption function after renal ischaemia, Radix Angelicae Sinensis polysaccharide can be by the macrophage in direct and (or) indirect pathway activation hematopoieticmicroenviron-ment, lymphocyte etc., also can stimulate muscular tissue, promote it to produce the hematopoietic regulation factor, and then promotion functions hematopoietic stem cell granular leukocyte macrophage colony becomes the proliferation and differentiation of unit (CFU-GM), stimulate the effects such as proliferation of Bone Marrow CFU-GM hemopoietic.
The Radix Paeoniae Alba: cool in nature, bitter in the mouth acid, is slightly cold, and has blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain.The effects such as astringing YIN to stop sweating, are applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction anxious, dysentery stomachache, spontaneous sweating, metrorrhagia, are with inferior disease.In this product, contained paeoniflorin has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjusting blood glucose; Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.In addition, research shows: the Radix Paeoniae Alba has potentiation to the phagocytic function of macrophage.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.There is blood-activating and qi-promoting, the effects such as wind-expelling pain-stopping.Be usually used in menoxenia, amenorrhea dysmenorrhea, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, the diseases such as rheumatic arthralgia.Research shows: Rhizoma Chuanxiong water extraction liquid and alkaloid thereof can be expanded crown and blood vessel, increases coronary flow, improves myocardial ischemia situation; Rhizoma Chuanxiong total alkaloids and ligustrazine can make anesthetized dog vascular resistance decline, and brain, femoral artery and lower extremity blood flow amount are increased; Ligustrazine extends the platelet aggregation time of ADP induction in vitro, and the platelet of having assembled is had to depolymerisation.
Carapax Trionycis: salty in the mouth, cold nature.Return liver, kidney channel.Have nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, brings down a fever except effects such as steamings.Be usually used in fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea ， WEIJIA, the diseases such as chronic malaria malaria with splenomegaly.Experiment shows: contained Trionyx sinensis Wiegmann polysaccharide in this product, can show the haematolysis ability that improves mice plaque forming cells, and promote hemolytic antibody to generate; And strengthen mice delayed hypersensitivity.
Semen Litchi: sweet in the mouth, micro-hardship, warm in nature.Return liver, kidney channel.There is promoting QI to circulate and dispersing the agglomeration of the pathogens, the effects such as cold-dispelling pain-relieving.Be usually used in colic of cold type stomachache, the diseases such as painful and swollen testis.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.GUIXIN, Liver Channel.There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effects such as relieving restlessness clear away heart-fire.Be usually used in menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, the diseases such as angina pectoris.This product has effect of slight lifting hypertension cardiac output and left ventricular work amount.In addition, also there is coronary artery dilator, improve myocardial ischemia situation, with all worries set aside, blood sugar lowering and the effect such as antibacterial reduce blood pressure, calm the nerves.
Carapax et Plastrum Testudinis: salty in the mouth, sweet, property is flat.Enter the heart, spleen, Liver Channel.There is YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, the effects such as strong bone.Be usually used in deficiency of kidney yin, hectic fever due to YIN-deficiency consumptive fever, spits blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, the diseases such as non-closure of fontanels jin infants.
Colla cornus cervi: sweet in the mouth, salty, warm in nature.Return kidney, Liver Channel.There is temperature compensation Liver and kidney, the effects such as beneficial intensive culture blood.Be usually used in sexual impotence spermatorrhea, the acid of waist knee joint is cold, asthenia weakness and emaciation, metrostaxis, the hematuria of having blood in stool, the carbuncle of yin nature disease such as swell and ache.Research shows: this product can promote the erythrocyte in peripheral blood, leukocyte, and hematoblastic amount increases.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature.Return liver, kidney channel.There is the yin nourishing of enriching blood, the effects such as life essence-filling, marrow-benefitting.Be usually used in blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, the diseases such as metrorrhagia, also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, the disease such as pass out semen, quench one's thirst.Radix Rehmanniae Preparata decoct has gold ground hypertension, the effects such as blood pressure, serum cholesterol and triglyceride.
Rhizoma Polygonati: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.There is boosting qi and nourishing yin, spleen invigorating, lung moistening, the effects such as kidney tonifying.Be usually used in weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, the interior-heat disease such as quench one's thirst.Research shows: this product also has resisting pathogenic microbes, resisting fatigue, antioxidation, slow down aging, hemostasis, obviously increases the effect such as coronary flow, antiviral.
Radix Morindae Officinalis: slightly warm in nature. acrid in the mouth, sweet. nontoxic.Return kidney, Liver Channel.There is kidney-replenishing, bone and muscle strengthening, the effects such as wind-damp dispelling.Being usually used in strong wind pathogen. impotence does not rise. bone and muscle strengthening. settling five organs invigorating middle warmer. increase the diseases such as will QI invigorating.This product has propagation and the differentiation of hematopoietic stem cell of promotion, or may be the generation by promoting various Hemopoietic factors and cytokine and indirectly promote the proliferation and differentiation of hematopoietic stem cell; There is the effect such as obvious anti-hypoxia reoxygenation injury, protection cardiac muscle; Radix Morindae Officinalis has enhancing body reserve, increases fatigue resistance, improves the self-regulation function of body, improve body in the time that anoxia stimulates stress, compensatory capacity, thereby the resistance of enhancing body; Breeder reaction is had to obvious facilitation, and can obviously strengthen splenocyte antibody formation number.
Rhizoma Alismatis: sweet in the mouth, cold in nature.Return kidney, urinary bladder channel.There is diuresis, the effects such as clearing away damp-heat.Be usually used in dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; The diseases such as hyperlipidemia.Research shows: this product has obvious cholesterol reducing effect and study of anti-atherogenic effect; The rabbit isolated aorta condition that alisol extract causes epinephrine is in vitro shunk relexation slowly; The rub contraction of the Rabbit thoracic aorta that alcohol can suppress to be caused by angiotensin of Rhizoma Alismatis, its contraction has dose dependent; The Rhizoma Alismatis alcohol isolated heart Perfusion that rubs reduces cardiac output and heart rate and left ventricular pressure as seen, but can increase coronary flow; Antiplatelet aggregation, antithrombotic form and promote the effects such as plasmin activity.
The invention has the advantages that:
The present invention for the treatment of varicocele have that determined curative effect, medical expense are cheap, preparation and instructions of taking easy, and it is little to have no side effect, and controls the advantages such as recurrence rate after healing is low.
Detailed description of the invention:
Embodiment 1:
Treat a Chinese medicine composition for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 18 parts of Herba Epimedii, 15 parts of Radix Angelicae Sinensis, 15 parts of the Radix Paeoniae Albas, 15 parts of Rhizoma Chuanxiongs, 15 parts of Carapax Trionycis, 15 parts of Semen Litchis, 15 parts of Radix Salviae Miltiorrhizaes, 12 parts of Carapax et Plastrum Testudiniss, 12 parts of Colla cornus cervis, 12 parts, Radix Rehmanniae Preparata, 12 parts of Rhizoma Polygonatis, 12 parts of Radix Morindae Officinaliss, 12 parts of Rhizoma Alismatis.
Preparation method:
Get by weight ratio that after Carapax Trionycis, Carapax et Plastrum Testudinis, Colla cornus cervi mix, to be brewed into cream for subsequent use, other raw material is decocted after 3 times, filtering medicinal residues, be condensed into original volume 25% after add the ointment of making of Carapax Trionycis, Carapax et Plastrum Testudinis, Cornu Cervi, after fully stirring, be condensed into dry extract, be ground into after 400 order fine powders, add again typical additives in pharmaceutics, after sterilizing, can make various common formulations.
Embodiment 2:
Treat a Chinese medicine composition for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 20 parts of Herba Epimedii, 15 parts of Radix Angelicae Sinensis, 20 parts of the Radix Paeoniae Albas, 15 parts of Rhizoma Chuanxiongs, 25 parts of Carapax Trionycis, 20 parts of Semen Litchis, 25 parts of Radix Salviae Miltiorrhizaes, 18 parts of Carapax et Plastrum Testudiniss, 18 parts of Colla cornus cervis, 15 parts, Radix Rehmanniae Preparata, 15 parts of Rhizoma Polygonatis, 15 parts of Radix Morindae Officinaliss, 15 parts of Rhizoma Alismatis.
Preparation method:
Get by weight ratio that after Carapax Trionycis, Carapax et Plastrum Testudinis, Colla cornus cervi mix, to be brewed into cream for subsequent use, other raw material is decocted after 3 times, filtering medicinal residues, be condensed into original volume 25% after add the ointment of making of Carapax Trionycis, Carapax et Plastrum Testudinis, Cornu Cervi, after fully stirring, be condensed into dry extract, be ground into after 400 order fine powders, add again typical additives in pharmaceutics, after sterilizing, can make various common formulations.
Embodiment 3:
Treat a Chinese medicine composition for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 18 parts of Herba Epimedii, 20 parts of Radix Angelicae Sinensis, 25 parts of the Radix Paeoniae Albas, 22 parts of Rhizoma Chuanxiongs, 30 parts of Carapax Trionycis, 18 parts of Semen Litchis, 25 parts of Radix Salviae Miltiorrhizaes, 20 parts of Carapax et Plastrum Testudiniss, 20 parts of Colla cornus cervis, 20 parts, Radix Rehmanniae Preparata, 18 parts of Rhizoma Polygonatis, 15 parts of Radix Morindae Officinaliss, 20 parts of Rhizoma Alismatis.
Preparation method:
Get by weight ratio that after Carapax Trionycis, Carapax et Plastrum Testudinis, Colla cornus cervi mix, to be brewed into cream for subsequent use, other raw material is decocted after 3 times, filtering medicinal residues, be condensed into original volume 25% after add the ointment of making of Carapax Trionycis, Carapax et Plastrum Testudinis, Cornu Cervi, after fully stirring, be condensed into dry extract, be ground into after 400 order fine powders, add again typical additives in pharmaceutics, after sterilizing, can make various common formulations.
Claims (2)
1. treat a Chinese medicine composition for varicocele, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Herba Epimedii 10-25 part, Radix Angelicae Sinensis 10-25 part, Radix Paeoniae Alba 10-30 part, Rhizoma Chuanxiong 10-30 part, Carapax Trionycis 10-30 part, Semen Litchi 10-30 part, Radix Salviae Miltiorrhizae 10-30 part, Carapax et Plastrum Testudinis 10-20 part, Colla cornus cervi 10-20 part, Radix Rehmanniae Preparata 10-20 part, Rhizoma Polygonati 10-20 part, Radix Morindae Officinalis 10-20 part, Rhizoma Alismatis 10-20 part.
2. according to a kind of Chinese medicine composition for the treatment of varicocele described in claim 1, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 18 parts of Herba Epimedii, 15 parts of Radix Angelicae Sinensis, 15 parts of the Radix Paeoniae Albas, 15 parts of Rhizoma Chuanxiongs, 15 parts of Carapax Trionycis, 15 parts of Semen Litchis, 15 parts of Radix Salviae Miltiorrhizaes, 12 parts of Carapax et Plastrum Testudiniss, 12 parts of Colla cornus cervis, 12 parts, Radix Rehmanniae Preparata, 12 parts of Rhizoma Polygonatis, 12 parts of Radix Morindae Officinaliss, 12 parts of Rhizoma Alismatis.
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| CN201410296783.2A CN104013810A (en) | 2014-06-28 | 2014-06-28 | Traditional Chinese medicine (TCM) composition for treating varicocele |
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| CN201410296783.2A CN104013810A (en) | 2014-06-28 | 2014-06-28 | Traditional Chinese medicine (TCM) composition for treating varicocele |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213797A (en) * | 2015-10-27 | 2016-01-06 | 林亚梅 | A kind of Chinese medicine being used for the treatment of varicocele |
| CN110840906A (en) * | 2019-12-02 | 2020-02-28 | 遵义医科大学 | Application of icariin in preparation of medicine for treating hypoxic pulmonary hypertension |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1911327A (en) * | 2006-08-09 | 2007-02-14 | 黄志良 | Decoction of herbal medicine for treating deficiency of live and kidney type cirsocele, and its preparing method |
-
2014
- 2014-06-28 CN CN201410296783.2A patent/CN104013810A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1911327A (en) * | 2006-08-09 | 2007-02-14 | 黄志良 | Decoction of herbal medicine for treating deficiency of live and kidney type cirsocele, and its preparing method |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213797A (en) * | 2015-10-27 | 2016-01-06 | 林亚梅 | A kind of Chinese medicine being used for the treatment of varicocele |
| CN110840906A (en) * | 2019-12-02 | 2020-02-28 | 遵义医科大学 | Application of icariin in preparation of medicine for treating hypoxic pulmonary hypertension |
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Application publication date: 20140903 |
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