A kind of livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation and its preparation method and application
Technical field
The present invention relates to animal feed additive field, particularly a kind of livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, and preparation method thereof and application in livestock and poultry cultivation.
Background technology
In livestock and poultry cultivation field, animal prevent and cure diseases with the raising of output be close-connected together with, the enteron aisle of animal, very abundant microbial population and digestion fermentoid population is there is in the enteron aisle of particularly herbivore or Omnivore, microbial population and the digestion fermentoid population of balance are conducive to animal to the decomposition of food and absorption, strengthen meat feed ratio.But in some cases, when such as infection virus or feed kind change, this balance will change, and cause animal immunizing power low, digestive function is deteriorated, and the death rate raises, and finally causes huge loss to raiser.
In order to prevent and improve above-mentioned situation, market has existed a large amount of animal formulations that can promote to digest, the kind of medicament developed into Integrated TCM preparation various in style, pure Chinese medicinal preparation, Traditional Chinese medicine probiotic in conjunction with preparation etc. by former single Western medicine class.
As: add kind catalogue (2008) according to the feed that the Ministry of Agriculture promulgates, select saccharomycete: provide a large amount of mycoproteins, the nutriments such as abundant B family vitamin, improve fowl poultry immune and production performance; Bacillus: regulating intestinal canal colony balance; Enterococcus: can field planting in animal and bird intestines, reduces the effects such as intestinal pH.< People's Republic of China (PRC) veterinary drug allusion quotation > 2010 editions contained Chinese medicinal formulaes Chinese herbal medicines such as Pingwei San is picked up with the fingers by betel nut, mountain, rhizoma atractylodis, dried orange peel, the bark of official magnolia, Radix Glycyrrhizae that help digestion form, function is mainly digesting and appetizing, cure mainly domestic animals (horse, ox, sheep, pig) gastrointestinal retention, indigestion is the health care good recipe of domestic animals food digesting stomach fortifying.But it is simply extensive to there is production technology in the said goods or formula, each prescription composition is done things in his own way substantially, be difficult to reach each Effective Component of Chinese Medicine that makes produced after decocting fully leach, fully carry out physical-chemical reaction each other, mutual coordination, the effect that its absorptivity and drug effect significantly promote, therefore bioavailability is low, absorb not exclusively, so using dosage comparatively large (every 1000kg feed must add 15-20kg), onset comparatively slow (generally needing to use 3-5 talent to have first meeting effect continuously), the course for the treatment of longer (needing 7-10 talent to cure), narrow application range (be only applicable to domestic animals and do not have the indication of bird aspect), therefore use cost is relatively high, cost performance is lower, constrain the application of this prescription on livestock and poultry breeding industry.
Summary of the invention
The present invention aims to provide a kind ofly to be had spleen benefiting and stimulating the appetite, promotes to digest and assimilate, enhancing development, raising immunologic function, improve resistance against diseases, consumption is little, rapid-action, cost performance is high livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, another object of the present invention is the preparation method providing these livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, and its application in livestock and poultry cultivation.
The scheme of a kind of livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation of the present invention is: a kind of livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, be made up of complex enzyme formulation, effective microorganism preparation, yeast cell wall polysaccharide and micro-powder of Chinese herbs, the weight portion of described complex enzyme formulation, effective microorganism preparation, yeast cell wall polysaccharide and micro-powder of Chinese herbs is respectively 1.5 ~ 2.5 parts, 4 ~ 5 parts, 3.5 ~ 4.5 parts, 88 ~ 91 parts; ; Described micro-powder of Chinese herbs is betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus through decocting, concentrated, meal, absorption, drying, the PROCESS FOR TREATMENT such as micro mist mixture, the weight ratio of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus is 10 ~ 12:7.5 ~ 9:12 ~ 15:16 ~ 12:16 ~ 12:7.5 ~ 9:6 ~ 7:7 ~ 8:6 ~ 7.
Preferably, the weight portion of described complex enzyme formulation, effective microorganism preparation, yeast cell wall polysaccharide and micro-powder of Chinese herbs is respectively 1.7 ~ 2.2 parts, 4.5 ~ 4.8 parts, 3.8 ~ 4.2 parts, 90 ~ 88.8 parts.
Preferably, the weight ratio of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus is 10.5 ~ 11.5:8 ~ 8.5:12.8 ~ 14.2:14.8 ~ 13:15 ~ 13:8 ~ 8.5:6.2 ~ 6.8:7.2 ~ 7.8:6.3 ~ 6.7.
It should be noted that, in yeast cell wall polysaccharide, main component is beta glucan and manna oligosacchride, the manna oligosacchride of the beta glucan containing at least 150g in the yeast cell wall polysaccharide of wherein every kg weight and at least 150g, preferably beta glucan is 200g, and manna oligosacchride is 200g.
Above-mentioned livestock and poultry with in nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, described complex enzyme formulation is the combination of at least two kinds in zytase, 1,4 beta-glucanase, cellulase, pectase, amylase, protease.
Preferably, in described complex enzyme formulation, every kg contains the enzyme classes of following content: zytase 2000 ~ 2,400 ten thousand U, 1,4 beta-glucanase 7300 ~ 7,700 ten thousand U, cellulase 1.15 ~ 1.35 hundred million U.
More preferably, in described complex enzyme formulation, every kg contains the enzyme classes of following content: zytase 2000 ~ 2,400 ten thousand U, 1,4 beta-glucanase 7300 ~ 7,700 ten thousand U, cellulase 1.15 ~ 1.35 hundred million U, pectase 40 ~ 600,000 U.
More preferably, in described complex enzyme formulation, every kg contains the enzyme classes of following content: zytase 2000 ~ 2,400 ten thousand U, 1,4 beta-glucanase 7300 ~ 7,700 ten thousand U, cellulase 1.15 ~ 1.35 hundred million U, pectase 40 ~ 600,000 U, amylase 2 00 ~ 3,000,000 U.
More preferably, in described complex enzyme formulation, every kg contains the enzyme classes of following content: zytase 2000 ~ 2,400 ten thousand U, 1,4 beta-glucanase 7300 ~ 7,700 ten thousand U, cellulase 1.15 ~ 1.35 hundred million U, pectase 40 ~ 600,000 U, amylase 2 00 ~ 3,000,000 U, protease 700 ~ 8,000,000 U.
Above-mentioned livestock and poultry with in nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, described effective microorganism preparation is at least one in bacillus subtilis, lichens brood cell bacterium, natto Bacillus or multiple combination.
Preferably, in described effective microorganism preparation, every kg weight contains all kinds of beneficial microbes of following content: bacillus subtilis >=15,000,000,000,000 cfu, lichens brood cell bacterium >=4.5 trillion cfu.
More preferably, in described effective microorganism preparation, every kg weight contains all kinds of beneficial microbes of following content: bacillus subtilis >=15,000,000,000,000 cfu, lichens brood cell bacterium >=4.5 trillion cfu; Natto Bacillus >=2.5 trillion cfu.
Above-mentioned livestock and poultry with in nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, described micro-powder of Chinese herbs is obtained by following steps:
Step 1: take betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus by above-mentioned weight ratio;
Step 2: betel nut step 1 taken, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae carry out cleaning and impurities removing, get the drinking water of 2 ~ 3 times of gross weight of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae are added in drinking water and soaks 5 ~ 7 hours, then rear constant temperature 80 ~ 85 DEG C decoction 1 ~ 1.5 hour is boiled in heating, it is heavily 1/8 ~ 1/12 of former amount of water to liquid that finally heating boils 30 minutes, is separated upper liquid and solid medicine slag blanket;
Step 3: step 2 gained upper liquid put into concentration pan heating be concentrated into heavily for upper liquid 1/4 ~ 1/5 stiff paste, stiff paste density is about 1.38 ~ 1.40g/cm
3(70 DEG C);
Step 4: the solid medicine slag blanket of step 2 gained is put into drying box with 70 ~ 75 DEG C of dryings, water content≤8.0% weight portion of the dry dregs of a decoction obtained after drying;
Step 5: the Medicated Leaven taken in step 1, Fructus Hordei Germinatus are mixed with the dry dregs of a decoction that step 4 obtains, and pulverize with pulverizer, obtaining particle diameter is 35 ~ 45 object meal;
Step 6: by the stiff paste in step 3 and the meal mix and blend in step 5, until the Chinese medicine meal of uniformly loose humidity;
Step 7: the Chinese medicine meal in step 6 is put into drying box with 70 ~ 75 DEG C of dryings, water content≤8.0% weight portion of the dry Chinese medicine meal obtained after drying;
Step 8: the Chinese medicine meal traditional Chinese medicine fine powder machine in step 7 is shattered, obtains 90 ~ 110 object micro-powder of Chinese herbs.
The present invention also provides the preparation method of above-mentioned livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, comprises the following steps:
Step 1: take complex enzyme and the mixing of equivalent micro-powder of Chinese herbs by weight ratio according to claim 1, cross 40 order stainless steel sifts, then take the mixing of mixture equivalent micro-powder of Chinese herbs, cross 40 order stainless steel sifts, premixed, stand-by;
Step 2: take the mixing of effective microorganism preparation, yeast cell wall polysaccharide and equivalent micro-powder of Chinese herbs by weight ratio according to claim 1, cross 40 order stainless steel sifts, premixed, stand-by;
Step 3: step 1 mixture, step 2 mixture and take remaining traditional Chinese medicine fine powder by weight, puts into three-dimensional mixer, mixes about 15-20 minute, obtain lark, color uniformity, without conglomeration, without the uniform powder of color spot;
Step 3: step 2 gained mixture is carried out the detections such as moisture content, granularity, discriminating on request, carries out packing after qualified on request, sealing, vanning, warehouse entry.
Examination criteria:
1. moisture content measures according to aquametry (Chinese veterinary pharmacopoeia version in 2010 two annex 60 pages), must not surpass 10%;
2. granularity: according to granulometry (Chinese veterinary pharmacopoeia version in 2010 two annex 81 pages) measure, all by aperture be 0.42mm analyze sieve, aperture be 0.25mm analyze sieve oversize must not be greater than 10%;
3. differentiate that (1) gets this product, puts basis of microscopic observation: endosperm fragment is colourless, and wall is thicker, has more great similar round pit.Pericarp lithocyte lilac red, redness or yellowish-brown, similar round or polygonal, diameter about to 125 μm.Needle-like calcium oxalate crystal is tiny, long 5 ~ 32 μm, is filled in brokenly in parenchyma cell.Lithocyte is branched, wall thickness, and laminated striation is obvious.Around fibre bundle, parenchyma cell is containing calcium oxalate prismatic crystal, forms crystal fiber.Calcium oxalate prismatic crystal is present in parenchymal tissue in flakes.
In the preparation method of above-mentioned livestock and poultry with nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, described complex enzyme formulation is the combination of at least two kinds in zytase, 1,4 beta-glucanase, cellulase, pectase, amylase, protease.
In the preparation method of above-mentioned livestock and poultry with nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, described effective microorganism preparation is one or more in bacillus subtilis, natto Bacillus, lichens brood cell bacterium.
In the preparation method of above-mentioned livestock and poultry with nonreactive growth promotion compound traditional Chinese veterinary medicine preparation, described Chinese medical extract is obtained by following concentration and extraction process:
Step 1: take betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus by above-mentioned weight ratio;
Step 2: betel nut step 1 taken, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae carry out cleaning and impurities removing, get the drinking water of 2 ~ 3 times of gross weight of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae are added in drinking water and soaks 5 ~ 7 hours, then rear constant temperature 80 ~ 85 DEG C decoction 1 ~ 1.5 hour is boiled in heating, it is heavily 1/8 ~ 1/12 of former amount of water to liquid that finally heating boils 30 minutes, is separated upper liquid and solid medicine slag blanket;
Step 3: step 2 gained upper liquid put into concentration pan heating be concentrated into heavily for upper liquid 1/4 ~ 1/5 stiff paste, stiff paste density is about 1.38 ~ 1.40g/cm
3(70 DEG C);
Step 4: the solid medicine slag blanket of step 2 gained is put into drying box with 70 ~ 75 DEG C of dryings, water content≤8.0% weight portion of the dry dregs of a decoction obtained after drying;
Step 5: the Medicated Leaven taken in step 1, Fructus Hordei Germinatus are mixed with the dry dregs of a decoction that step 4 obtains, and pulverize with pulverizer, obtaining particle diameter is 35 ~ 45 object meal;
Step 6: by the stiff paste in step 3 and the meal mix and blend in step 5, until the Chinese medicine meal of uniformly loose humidity;
Step 7: the Chinese medicine meal in step 6 is put into drying box with 70 ~ 75 DEG C of dryings, water content≤8.0% weight portion of the dry Chinese medicine meal obtained after drying;
Step 8: the Chinese medicine meal traditional Chinese medicine fine powder machine in step 7 is shattered, obtains 90 ~ 110 object micro-powder of Chinese herbs.
The present invention also provides the above-mentioned application process of livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation in livestock and poultry cultivation, described livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation is added in the daily ration of livestock and poultry, the ratio of described livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation and the daily ration of livestock and poultry for: add the livestock and poultry nonreactive growth promotion compound traditional Chinese veterinary medicine preparation described in 2 ~ 3kg in the daily ration of the livestock and poultry of 1000kg
The present invention is improved on the basis of Chinese veterinary drug preparation " help digestion Pingwei San " prescription, by adding appropriate enzyme preparation, polysaccharide, effective microorganism preparation and to pharmaceutical decocting piece through decoct, concentrated, meal, absorption, dry, the special process process of micro mist etc., revolutionize former prescription using dosage large, onset is slow, the course for the treatment of is long, the shortcoming that use cost is high, and expand the scope of application, be not only applicable to horse, ox, sheep, the domestic animals such as pig, chicken can also be used for, duck, goose, the birds such as dove are for the control of disease of digestive system and health care, and have raising immunity clearly, effect of enhancing development.
The present invention adds the digestive ferment compositions such as protease, amylase, zytase, cellulase in former prescription on the one hand, strengthen the chemical digestion of stomach and intestine, the nutriment in feed is made to be able to thoroughly, fully digest, thus improve the biological availability to feed, alleviate the ight soil bad smell caused because nutriment is not fully absorbed; Simultaneously due to the abundant digestion of nutriment, avoid the infull product of protein digestibility if amine is to the stimulation of kidney and murder by poisoning, indirectly correct kidney swelling.Two aspect the present invention add the beneficial bacterium compositions such as bacillus subtilis, natto Bacillus, lichens brood cell bacterium in prescription, flora in balance intestines and stomach, the profitable strain of participation digestive function is made to become dominant microflora, strengthen biological digestion and the removing toxic substances transformation function to harmful substance, alleviate the load of liver, indirectly impel the recovery of damaged liver function; Impel the ability of the synthetic vitamin of profitable strain, alleviate the hypovitaminosis caused owing to abusing antimicrobial, correct bio-digestion hypodynamia.On the other hand the present invention adds yeast cell wall polysaccharide in prescription, can bacterium and mycotoxin in efficient adsorption feed, significantly improves animal immunizing power, improves livestock and poultry production performance, reduce feedstuff-meat ratio, reduce harmful toxins to the injury of body.
What is more important, fuling peel composition is increased in prescription of the present invention, strengthen eliminating dampness and diuresis, effect of benefit spleen and stomach, in addition, increases Medicated Leaven and Fructus Hordei Germinatus, make it to carry out 5 with each component in Chinese medicine to join, improve the digestive function of animal significantly, be particularly conducive to the recovery of intestinal flora and enzyme equilibrium, the course for the treatment of of animal intestine gastric disease can greatly be shortened.Simultaneously each prepared slices of Chinese crude drugs by soaking, decocting, concentrated, drying, absorption, the technique such as ultramicro grinding, each Effective Component of Chinese Medicine is fully leached, fully carries out physical-chemical reaction each other, its absorptivity and bioavilability are significantly improved, and are more than 5 times of ordinary powder.
The present invention is by above compatibility and process modification, cut the defect that the end solves former prescription, this product 2 ~ 3kg is added by every 1000kg animal and fowl fodder, just visible ight soil is shaping to use second day, the smelly ammonia taste of excrement alleviates, to search for food increase, the positive effect that defecation reduces, within 3 ~ 5 days, be can reach digesting and appetizing a course for the treatment of, immunity moderation function, improve resistance against diseases, improve food conversion ratio, reduce diarrhea rate, reduce the ideal effect of ight soil ammonia stink, use the result of use that just can meet or exceed a course for the treatment of and add former prescription 10kg in former prescription every 1000kg animal and fowl fodder every other week, use cost reduces by more than 1 times than former prescription, and have good growth promoting effects, improve effect of resistance against diseases, the control of disease of digestive system can use by substitute antibiotics completely.And antibiotic-free and growth promotion forbidden drug composition, drug residue free, has no drug resistance, and composite culture benefit is remarkable, meets the nonreactive cultivation policy that current China advocates completely, has good popularizing application prospect.
Detailed description of the invention
Below in conjunction with detailed description of the invention, technical scheme of the present invention is described in further detail, but does not form any limitation of the invention.
Embodiment 1
1, the preparation of micro-powder of Chinese herbs
Step 1.1: take betel nut 11.5kg, hawthorn 8Kg, rhizoma atractylodis 13.5kg, dried orange peel 14.8kg, fuling peel 15kg, bark of official magnolia 7.9kg, Radix Glycyrrhizae 6.8kg, Medicated Leaven 7.6kg, Fructus Hordei Germinatus 6.5kg;
Step 1.2: the betel nut taken, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae are carried out clean and impurities removing is placed in 200kg drinking water and soaks 6 hours, then rear constant temperature 80 ~ 85 DEG C decoction 1.5 hours is boiled in heating, finally heating is boiled 30 minutes until the upper liquid that can leach is 20 ± 1kg, is separated upper liquid and solid medicine slag blanket;
Step 1.3: upper liquid is put into concentration pan heating and be concentrated into heavy 4.5 ± 0.5kg, obtain stiff paste, stiff paste density is about 1.38 ~ 1.40g/cm
3(70 DEG C);
Step 1.4: solid medicine slag blanket puts into drying box with 70 ~ 75 DEG C of dryings, the water content of the dry dregs of a decoction obtained after drying needs≤8.0% weight portion;
Step 1.5: the Medicated Leaven taken in step 1.1, Fructus Hordei Germinatus are mixed with the dry dregs of a decoction that step 4 obtains, and pulverize with pulverizer, obtaining particle diameter is 40 object meal;
Step 1.6: by the stiff paste in step 1.3 and the meal mix and blend in step 5, until the Chinese medicine meal of uniformly loose humidity;
Step 1.7: the Chinese medicine meal in step 1.6 is put into drying box with 70 ~ 75 DEG C of dryings, water content≤8.0% weight portion of the dry Chinese medicine meal obtained after drying;
Step 1.8: the Chinese medicine meal traditional Chinese medicine fine powder machine in step 1.7 is shattered, obtains 90 ~ 110 object micro-powder of Chinese herbs.
2, the livestock and poultry preparation of nonreactive growth promotion compound traditional Chinese veterinary medicine preparation
Step 2.1: getting complex enzyme formulation is 2kg, micro-powder of Chinese herbs 2kg mixed 40 order stainless steel sifts, then claimed 4kg traditional Chinese medicine fine powder to mix with mixture, crossed 40 order stainless steel sifts, premixed, stand-by; Wherein, specifically comprise in every kg complex enzyme formulation: zytase 2,200 ten thousand U, 1,4 beta-glucanase 7,500 ten thousand U, cellulase 1.25 hundred million U, pectase 500,000 U, amylase 2 500,000 U, protease 7,500,000 U.
Step 2.2: getting effective microorganism preparation is 4.5kg, and yeast cell wall polysaccharide is 4kg, and micro-powder of Chinese herbs is 8.5kg, mixing, crosses 40 order stainless steel sifts, premixed, stand-by; Wherein every kg effective microorganism preparation specifically comprises: bacillus subtilis >=15,000,000,000,000 cfu, lichens brood cell bacterium >=4.5 trillion cfu; Natto Bacillus >=2.5 trillion cfu.Containing beta glucan in every kg yeast cell wall polysaccharide is 200g, and manna oligosacchride is 200g;
Step 2.3: be that 79.5kg puts into three-dimensional mixer by the mixture obtained in step 2.1, step 2.2 and micro-powder of Chinese herbs, mixes about 15-20 minute, obtains lark, color uniformity, without conglomeration, without the uniform powder of color spot;
Step 2.4: step 2.3 gained uniform powder is carried out moisture content, granularity, discriminating etc. on request and detects (asking inventor to provide examination criteria), carry out packing after qualified on request, sealing, vanning, warehouse entry.
Obtain sample 1.
Examination criteria:
1. moisture content measures according to aquametry (Chinese veterinary pharmacopoeia version in 2010 two annex 60 pages), must not surpass 10%;
2. granularity: according to granulometry (Chinese veterinary pharmacopoeia version in 2010 two annex 81 pages) measure, all by aperture be 0.42mm analyze sieve, aperture be 0.25mm analyze sieve oversize must not be greater than 10%;
3. differentiate that (1) gets this product, puts basis of microscopic observation: endosperm fragment is colourless, and wall is thicker, has more great similar round pit.Pericarp lithocyte lilac red, redness or yellowish-brown, similar round or polygonal, diameter about to 125 μm.Needle-like calcium oxalate crystal is tiny, long 5 ~ 32 μm, is filled in brokenly in parenchyma cell.Lithocyte is branched, wall thickness, and laminated striation is obvious.Around fibre bundle, parenchyma cell is containing calcium oxalate prismatic crystal, forms crystal fiber.Calcium oxalate prismatic crystal is present in parenchymal tissue in flakes.
Embodiment 2:
The present embodiment is with identical, different place of filling a prescription with the preparation method of embodiment 1,
Specifically comprise in every kg complex enzyme formulation: zytase 2,200 ten thousand U, 1,4 beta-glucanase 7,500 ten thousand U, cellulase 1.25 hundred million U.
Embodiment 3:
The present embodiment is with identical, different place of filling a prescription with the preparation method of embodiment 1,
Specifically comprise in every kg complex enzyme formulation: zytase 2,200 ten thousand U, 1,4 beta-glucanase 7,500 ten thousand U, cellulase 1.25 hundred million U, pectase 500,000 U, amylase 2 500,000 U.
Embodiment 4:
The present embodiment is with identical, different place of filling a prescription with the preparation method of embodiment 1,
Every kg effective microorganism preparation specifically comprises: bacillus subtilis >=15,000,000,000,000 cfu, lichens brood cell bacterium >=4.5 trillion cfu.
Embodiment 5:
The preparation method of the present embodiment and embodiment 1 with fill a prescription identical, different places is, the each Chinese medicine weight taken in step 1.1 is: betel nut 10.8kg, hawthorn 8.9kg, rhizoma atractylodis 12.2kg, dried orange peel 14.5kg, fuling peel 15.6kg, bark of official magnolia 7.5kg, Radix Glycyrrhizae 6.9kg, Medicated Leaven 7.0kg, Fructus Hordei Germinatus 6.4kg.
Embodiment 6:
The preparation method of the present embodiment and embodiment 1 with fill a prescription identical, different places is, the each Chinese medicine weight taken in step 1.1 is: betel nut 11.9kg, hawthorn 7.7kg, rhizoma atractylodis 14.7kg, dried orange peel 12.7kg, fuling peel 12.2kg, bark of official magnolia 8.9kg, Radix Glycyrrhizae 6.2kg, Medicated Leaven 7.9kg, Fructus Hordei Germinatus 7.0kg.
Embodiment 7:
The present embodiment is with identical, different place of filling a prescription with the preparation method of embodiment 6, the complex enzyme formulation 1.5kg taken in step 2.1, micro-powder of Chinese herbs 1.5kg; The effective microorganism preparation 4.2kg taken in step 2.2, yeast cell wall polysaccharide 4.3kg and micro-powder of Chinese herbs 8.5kg; The micro-powder of Chinese herbs taken in step 2.3 is 79kg.
Comparative example 1
Preparation contrast sample 1.
By Chinese veterinary pharmacopoeia version in 2010 two---help digestion Pingwei San standard, takes betel nut 14kg, hawthorn 33kg, rhizoma atractylodis 16kg, dried orange peel 18kg, bark of official magnolia 11kg, Radix Glycyrrhizae 8kg.With Chinese medicine coarse-cracking machine meal to about 20-24 order, then use traditional Chinese medicine fine powder machine fine powder to about 40-60 order, cross 40 order stainless steel sifts, put into three-dimensional mixer, mix about 15-20 minute, obtain lark, color uniformity, without conglomeration, without the uniform powder of color spot;
Sample 1 must be contrasted
Animal feeding embodiment 1
Sample 1 is on the impact of meat chicken production performance.
1, materials and methods
(1) material
Get the sample 1 of above-described embodiment 1 and contrast the test material of sample 1 (help digestion Pingwei San) as this animal feeding embodiment 1
(2) conceptual design
The fast large yellow-feather broiler of Wen Shi of 1 age in days unified raising after one week, randomly drawed 900, was divided into 3 groups, often organize 3 repetitions, each repetition 100, divide experiment I group, test II group, blank group, and take original body mass; Test I group and use sample 1 by feed mixing, test II group and use contrast sample 1 by feed mixing, blank group need not any medicated premix.Test I group of sample 1,2.5kg sample 1 of feeding and mix particulate material 1000kg, the sample 1 three days of feeding continuously every other week; Test II group of contrast sample 1,10kg contrast sample 1 of feeding and mix particulate material 1000kg, feed continuously every other week and contrast sample 1 three days; Blank group is fed normal chicken particulate material.Experimental group and blank group all adopt raises in cages, free choice feeding is drunk water, three groups, pellet is identical, record broiler chicken daily feed intake, regularly carry out immunity and cleaning hen house, weigh after 3 hours on an empty stomach in units of group weekly, freely drink water on an empty stomach, breeding cycle is 35 days, calculates each stage average daily gain, average daily ingestion amount, feedstuff-meat ratio and survival rate.The concrete formula of pellet is corn 55.3%, dregs of beans 36%, calcium monohydrogen phosphate 1.8%, stone flour 1%, fat oil 1.4%, fish meal 2.5%, premix 2%.
2, result and data
2.1 growth performances measure:
The initial average weight of 7 age in days: only test I group of 100.5g/, only tests II group of 101.3g/, and blank group 100.8g/ only.
Table one:
Result of the test shows:
Livestock and poultry of the present invention are added 2.5kg with nonreactive growth promotion compound traditional Chinese veterinary medicine preparation by every 1000kg feed and feed and raise experiment and show, its food digesting stomach fortifying, aid digestion, growth promotion, raising daily gain, reduce feedstuff-meat ratio, improve every production performance indexs such as survival rate and be all obviously better than the effect that every 1000kg feed adds 10kg " help digestion Pingwei San ", not only significantly improve the growth performance of broiler chicken, the resistance against diseases of broiler chicken can also be significantly improved; It is that column home does not have ammonia stink substantially that livestock and poultry of the present invention nonreactive of feeding growth promotion compound traditional Chinese veterinary medicine preparation experimental group and contrast groups are the most significantly distinguished, the dry slivering of chicken manure, substantially not there is intestines problem, and feather light is glossy, the overall speed of growth is comparatively average, using dosage is only 1/4th of contrast groups, and use cost reduces by more than 1 times than contrast groups.
Animal feeding embodiment 2
The prevention effect of sample 1 pair of ternary intestine of young pigs disease.
1, materials and methods
(1) material
Get the sample 1 of above-described embodiment 1 and contrast the test material of sample 1 (help digestion Pingwei San) as this animal feeding embodiment 2.
(2) conceptual design
Subjects is that source is consistent, same parity, the farrowing time is close, litter size is identical, and sex ratio is close, the Du great Chang ternary weanling pig that weight of weaning litter, body weight are close, be divided into experiment I group by paired experiment principle, test II group and blank group totally 3 groups, often organize 3 repetitions, each repetition 20, totally 180.Test I group of initial head counterpoise (10.21 ± 1.25) kg, test II group of initial head counterpoise (10.12 ± 1.25) kg, blank group initial head counterpoise (10.18 ± 1.25) kg, tests I group of sample 1 of feeding, feeds week about 3 days; Test II group of contrast sample 1 of feeding, feed week about 3 days; Blank group does not additionally add any medicated premix.2.5kg sample 1 mix fodder 1000kg, 10kg contrast sample 1 mix fodder 1000kg, allow piglet free choice feeding, feeding cycle be 50 days.Experimental group and blank group all to be thrown something and fed four particulate material every day, and period regularly cleans pig house, and vaccine program vaccinate.The concrete formula of particulate material is corn 54%, fine rice bran 5.94%, high-quality fish meal 5%, dregs of beans 31%, calcium monohydrogen phosphate 1.2%, stone flour 0.7%, salt 0.16%, premix 2.0%.
The diarrhoea frequency of control group and experimental group is recorded in 50 days.
2, result and data
Table two:
|
Test I group |
Test II group |
Blank group |
Initial average weight kg |
10.21 |
10.12 |
10.18 |
Average weight kg after 50 days |
42.71 |
40.62 |
37.18 |
Incidence of Diarrhea |
3.33% |
8.33% |
36.67% |
The death rate |
0% |
1.67% |
11.67% |
Daily gain g/ days |
650 |
610 |
540 |
Result of the test shows:
Livestock and poultry of the present invention are added 2.5kg with nonreactive growth promotion compound traditional Chinese veterinary medicine preparation by every 1000kg feed and feed and raise experiment and show, the effect that its digesting and appetizing, immunity moderation function, the resistance against diseases that improves, raising daily gain, the every growth performance index such as diarrhea rate, the minimizing death rate that reduces all obviously are better than every 1000kg feed interpolation 10kg " help digestion Pingwei San ", not only significantly improve the growth performance of piglet, significantly can also reduce the incidence of intestine of young pigs disease and improve resistance against diseases.It is that pig house does not have ammonia stink substantially that livestock and poultry of the present invention nonreactive of feeding growth promotion compound traditional Chinese veterinary medicine preparation experimental group and contrast groups are the most significantly distinguished, pig manure is comparatively dry, measure little, color depth, intestines problem significantly reduces, occur once in a while also very easily to recover, and the red hair of skin is bright, can eats and can sleep, the overall speed of growth is comparatively average, using dosage is only 1/4th of contrast groups, and use cost reduces by more than 1 times than contrast groups.
Animal feeding embodiment 3
The result for the treatment of of sample 1 pair of Intestine of Broiler disease.
1, materials and methods
(1) material
Get the sample 1 of above-described embodiment 1 and " the help digestion Pingwei San " test material as this animal feeding embodiment 3
(2) conceptual design
The fast large yellow-feather broiler of Wen Shi of 1 age in days unified raising after three weeks, randomly drawed 900, was divided into 3 groups, often organize 3 repetitions, each repetition 100, divide experiment I group, test II group, blank group, and claim initial average weight; Select mouldy pellet, the concrete content of the mark of this pellet is corn 55.3%, dregs of beans 38%, calcium monohydrogen phosphate 1.4%, stone flour 1%, salt 0.3%, oil 3%, premix 1%.Continuous nursing 2 days above-mentioned mouldy pellets, free choice feeding is drunk water, and feeds 2 days, does not digest the quantity of the many sick chickens of feed in record lassitude, ight soil jaundice, ight soil.Within 3rd day, rise to feed and raise normal not mouldy pellet, formula is with mouldy pellet is identical before, test I group and use sample 1 by feed mixing, test II group and use contrast sample 1 by feed mixing, blank group need not any medicated premix, 2.5kg sample 1 mix fodder 1000kg, 10kg contrasts sample 1 mix fodder 1000kg, free choice feeding is drunk water, feed continuously 7 days, record the quantity of disease chicken every day, continue record 7 days, weigh after 3 hours on an empty stomach in units of group after 7 days, freely drink water on an empty stomach.
2, result and data
Table three
|
Test I group |
Test II group |
Blank group |
Initial average weight (g) |
445.6 |
450.2 |
443.3 |
Average weight (g) after 7 days |
550.5 |
512.3 |
467.8 |
(only) on the 1st |
255 |
256 |
255 |
(only) on the 2nd |
252 |
254 |
258 |
(only) on the 3rd |
156 |
243 |
258 |
(only) on the 4th |
86 |
189 |
243 |
(only) on the 5th |
32 |
126 |
220 |
(only) on the 6th |
8 |
82 |
189 |
(only) on the 7th |
2 |
67 |
182 |
Result of the test shows:
Livestock and poultry of the present invention are added feeding of 2.5kg with nonreactive growth promotion compound traditional Chinese veterinary medicine preparation by every 1000kg feed and raise experiment and show; every growth performance index such as its digesting and appetizing, absorbing mycotoxin, immunity moderation function, the resistance against diseases that improves, protection function of intestinal canal, reduction diarrhea rate, the minimizing death rate is all obviously better than the effect that every 1000kg feed adds 10kg " help digestion Pingwei San "; not only significantly improve the resistivity of broiler chicken to harmful substances such as mycotoxins, significantly can also reduce the incidence of Intestine of Broiler disease and improve resistance against diseases.It is play chicken manure and obvious drying and moulding on the 3rd day that livestock and poultry of the present invention nonreactive of feeding growth promotion compound traditional Chinese veterinary medicine preparation experimental group and contrast groups are the most significantly distinguished, color from yellow is rare just turns Dark grey spiral shell meat-like, major part chicken spirit and appetite are recovered all substantially, the growth performances such as daily gain recover rapidly, and using dosage is only 1/4th of contrast groups, use cost reduces by more than 1 times than contrast groups.
Above-describedly be only preferred embodiment of the present invention, all do within the scope of the spirit and principles in the present invention any amendment, equivalently to replace and improvement etc., all should be included within protection scope of the present invention.