CN104012757A - Nonreactive growth-promoting compound veterinary medicine preparation for livestock as well as preparation method and application of preparation - Google Patents
Nonreactive growth-promoting compound veterinary medicine preparation for livestock as well as preparation method and application of preparation Download PDFInfo
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Abstract
The invention discloses a nonreactive growth-promoting compound veterinary medicine preparation for livestock. The nonreactive growth-promoting compound veterinary medicine preparation for livestock consists of the following ingredients in parts by weight: 1.5-2.5 parts of complex enzyme preparation, 4-5 parts of beneficial microbial preparation, 3.5-4.5 parts of yeast cell wall polysaccharide and 88-91 parts of traditional Chinese medicine micro powder. The invention aims at providing preparation for the nonreactive growth-promoting compound veterinary medicine preparation for livestock, which has effects of tonifying spleen and promoting appetite, promoting digestive absorption of nutrient substances, promoting growth and development, improving an immunologic function and improving disease resistance, and has the characteristics of being small in dosage, quick to become effective, high in cost performance, low in using cost, capable of being added for use in the long term, free of medicine resistance and withdrawal period, as well as a preparation method and application of the nonreactive growth-promoting compound veterinary medicine preparation for livestock.
Description
Technical field
The present invention relates to animal feed additive field, particularly nonreactive growth promotion compound herbal medicine preparation for a kind of livestock and poultry, and preparation method thereof and application in livestock and poultry cultivation.
Background technology
In livestock and poultry cultivation field, prevent and cure diseases and the raising of output of animal be close-connected together with, the enteron aisle of animal, particularly in the enteron aisle of herbivore or Omnivore, there is very abundant microbial population and digestion fermentoid population, the microbial population of balance and digestion fermentoid population are conducive to decomposition and the absorption of animal to food, strengthen meat feed ratio.But in some cases, such as infecting in the situation that virus or feed kind change, this balance will change, and causes animal immunizing power low, digestive function variation, the death rate raises, and finally causes huge loss to raiser.
In order to prevent and to improve above-mentioned situation, on market, there are a large amount of animal formulations that can promote digestion, the kind of medicament by former single Western medicine class develop into Chinese and Western medicine various in style in conjunction with preparation, pure Chinese medicinal preparation, Chinese medicine probio in conjunction with preparation etc.
As: the feed of promulgating according to the Ministry of Agriculture adds kind catalogue (2008), selects saccharomycete: a large amount of mycoproteins is provided, and the nutriments such as abundant B family vitamin, improve fowl poultry immune and production performance; Bacillus: regulating intestinal canal colony balance; Enterococcus: can field planting in animal and bird intestines, reduce the effects such as enteron aisle pH.The < People's Republic of China (PRC) 2010 editions contained Chinese medicinal formulaes of veterinary drug allusion quotation > help digestion Pingwei San by betel nut, mountain pick up with the fingers, the Chinese herbal medicine such as rhizoma atractylodis, dried orange peel, the bark of official magnolia, Radix Glycyrrhizae forms, function is mainly digesting and appetizing, cure mainly domestic animals (horse, ox, sheep, pig) gastrointestinal retention, indigestion is the health care good recipe of domestic animals food digesting stomach fortifying.But the said goods or formula exist production technology extensive simple, each prescription composition is done things in his own way substantially, being difficult to reach the each Effective Component of Chinese Medicine that makes producing after decocting fully leaches, fully carry out each other physical-chemical reaction, mutually coordinate, the effect that its absorptivity and drug effect significantly promote, therefore bioavailability is low, absorb not exclusively, so using dosage large (every 1000kg feed must add 15-20kg), onset slow (generally needing to use continuously 3-5 talent to have first meeting effect), grow the course for the treatment of (needing 7-10 talent to cure), narrow application range (be only applicable to domestic animals and there is no the indication of bird aspect), therefore use cost is relatively high, cost performance is lower, restrict the application of this prescription on livestock and poultry breeding industry.
Summary of the invention
The present invention aims to provide a kind ofly to be had spleen benefiting and stimulating the appetite, promotes to digest and assimilate, enhancing development, raising immunologic function, improve resistance against diseases, consumption is little, rapid-action, cost performance is high livestock and poultry nonreactive growth promotion compound herbal medicine preparation, another object of the present invention is to provide the preparation method of these livestock and poultry nonreactive growth promotion compound herbal medicine preparation, with and application in livestock and poultry cultivation.
A kind of livestock and poultry of the present invention by the scheme of nonreactive growth promotion compound herbal medicine preparation are: nonreactive growth promotion compound herbal medicine preparation for a kind of livestock and poultry, formed by complex enzyme formulation, effective microorganism preparation, yeast cell wall polysaccharide and micro-powder of Chinese herbs, the weight portion of described complex enzyme formulation, effective microorganism preparation, yeast cell wall polysaccharide and micro-powder of Chinese herbs is respectively 1.5～2.5 parts, 4～5 parts, 3.5～4.5 parts, 88～91 parts; ; Described micro-powder of Chinese herbs be betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus through decocting, the mixture of the PROCESS FOR TREATMENT such as concentrated, meal, absorption, dry, micro mist, the weight ratio of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus is 10～12:7.5～9:12～15:16～12:16～12:7.5～9:6～7:7～8:6～7.
Preferably, the weight portion of described complex enzyme formulation, effective microorganism preparation, yeast cell wall polysaccharide and micro-powder of Chinese herbs is respectively 1.7～2.2 parts, and 4.5～4.8 parts, 3.8～4.2 parts, 90～88.8 parts.
Preferably, the weight ratio of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus is 10.5～11.5:8～8.5:12.8～14.2:14.8～13:15～13:8～8.5:6.2～6.8:7.2～7.8:6.3～6.7.
It should be noted that, in yeast cell wall polysaccharide, main component is beta glucan and manna oligosacchride, wherein in the yeast cell wall polysaccharide of every kg weight, contain the beta glucan of 150g at least and the manna oligosacchride of 150g at least, being preferably beta glucan is 200g, and manna oligosacchride is 200g.
Above-mentioned livestock and poultry, with in nonreactive growth promotion compound herbal medicine preparation, described complex enzyme formulation is the combination of at least two kinds in zytase, 1,4 beta-glucanase, cellulase, pectase, amylase, protease.
Preferably, the enzyme classes that in described complex enzyme formulation, every kg contains following content: zytase 2000～2,400 ten thousand U, 1,4 beta-glucanase 7300～7,700 ten thousand U, cellulase 1.15～1.35 hundred million U.
More preferably, the enzyme classes that in described complex enzyme formulation, every kg contains following content: zytase 2000～2,400 ten thousand U, 1,4 beta-glucanase 7300～7,700 ten thousand U, cellulase 1.15～1.35 hundred million U, pectase 40～600,000 U.
More preferably, the enzyme classes that in described complex enzyme formulation, every kg contains following content: zytase 2000～2,400 ten thousand U, 1,4 beta-glucanase 7300～7,700 ten thousand U, cellulase 1.15～1.35 hundred million U, pectase 40～600,000 U, amylase 2 00～3,000,000 U.
More preferably, the enzyme classes that in described complex enzyme formulation, every kg contains following content: zytase 2000～2,400 ten thousand U, 1,4 beta-glucanase 7300～7,700 ten thousand U, cellulase 1.15～1.35 hundred million U, pectase 40～600,000 U, amylase 2 00～3,000,000 U, protease 700～8,000,000 U.
Above-mentioned livestock and poultry, with in nonreactive growth promotion compound herbal medicine preparation, described effective microorganism preparation is at least one or the multiple combination in bacillus subtilis, lichens brood cell bacterium, natto Bacillus.
Preferably, all kinds of beneficial microbes that in described effective microorganism preparation, every kg weight contains following content: bacillus subtilis >=15,000,000,000,000 cfu, lichens brood cell bacterium >=4.5 trillion cfu.
More preferably, all kinds of beneficial microbes that in described effective microorganism preparation, every kg weight contains following content: bacillus subtilis >=15,000,000,000,000 cfu, lichens brood cell bacterium >=4.5 trillion cfu; Natto Bacillus >=2.5 trillion cfu.
Above-mentioned livestock and poultry, with in nonreactive growth promotion compound herbal medicine preparation, described micro-powder of Chinese herbs obtains by following steps:
Step 1: take betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus by above-mentioned weight ratio;
Step 2: betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae that step 1 is taken are cleaned and impurities removing, get the drinking water of 2～3 times of the gross weight of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae are added in drinking water and soaked 5～7 hours, then 80～85 DEG C of decoctions of rear constant temperature 1～1.5 hour are boiled in heating, finally heating boil 30 minutes to liquid be heavily 1/8～1/12 of former amount of water, separate upper strata liquid and solid medicine slag blanket;
Step 3: step 2 gained upper strata liquid is put into concentration pan heating and be concentrated into heavily 1/4～1/5 the stiff paste for upper strata liquid, stiff paste density is about 1.38～1.40g/cm
3(70 DEG C);
Step 4: the solid medicine slag blanket of step 2 gained is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry dregs of a decoction that obtain after being dried;
Step 5: the dry dregs of a decoction that the Medicated Leaven taking in step 1, Fructus Hordei Germinatus are obtained with step 4 mix, and pulverize with pulverizer, obtaining particle diameter is 35～45 object meal;
Step 6: by the meal mix and blend in the stiff paste in step 3 and step 5, until become the Chinese medicine meal of even loose humidity;
Step 7: the Chinese medicine meal in step 6 is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry Chinese medicine meal obtaining after being dried;
Step 8: the Chinese medicine meal in step 7 is shattered with Chinese medicine fine powder machine, obtain 90～110 object micro-powder of Chinese herbs.
The present invention also provides the above-mentioned livestock and poultry preparation method of nonreactive growth promotion compound herbal medicine preparation, comprises the following steps:
Step 1: take complex enzyme and the mixing of equivalent micro-powder of Chinese herbs by weight ratio claimed in claim 1, cross 40 order stainless steel sifts, then take the mixing of mixture equivalent micro-powder of Chinese herbs, cross 40 order stainless steel sifts, premixed, stand-by;
Step 2: take effective microorganism preparation, yeast cell wall polysaccharide and equivalent micro-powder of Chinese herbs by weight ratio claimed in claim 1 and mix, cross 40 order stainless steel sifts, premixed, stand-by;
Step 3: step 1 mixture, step 2 mixture and take by weight remaining Chinese medicine fine powder, put into three-dimensional mixer, mix about 15-20 minute, obtain lark, color uniformity, without conglomeration, without the uniform powder of color spot;
Step 3: step 2 gained mixture is carried out to the detections such as moisture content, granularity, discriminating on request, carry out on request packing after qualified, sealing, vanning, warehouse entry.
Examination criteria:
1. moisture content is measured according to aquametry (60 pages of two annex of Chinese veterinary pharmacopoeia version in 2010), must not surpass 10%;
2. granularity: measuring according to granulometry (81 pages of two annex of Chinese veterinary pharmacopoeia version in 2010), is all that 0.42mm analyzes sieve by aperture, aperture is that 0.25mm analysis sieve oversize must not be greater than 10%;
3. this product is got in discriminating (1), puts micro-Microscopic observation: endosperm fragment is colourless, and wall is thicker, has more great similar round pit.Pericarp lithocyte lilac red, redness or yellowish-brown, similar round or polygonal, diameter to 125 μ m.Needle-like calcium oxalate crystal is tiny, and long 5～32 μ m, are filled in parenchyma cell brokenly.Lithocyte is branched, wall thickness, and laminated striation is obvious.Fibre bundle around parenchyma cell, containing calcium oxalate prismatic crystal, forms crystal fiber.Calcium oxalate prismatic crystal is present in parenchymal tissue in flakes.
In preparation method above-mentioned livestock and poultry with nonreactive growth promotion compound herbal medicine preparation, described complex enzyme formulation is the combination of at least two kinds in zytase, 1,4 beta-glucanase, cellulase, pectase, amylase, protease.
In preparation method above-mentioned livestock and poultry with nonreactive growth promotion compound herbal medicine preparation, described effective microorganism preparation is one or more in bacillus subtilis, natto Bacillus, lichens brood cell bacterium.
In preparation method above-mentioned livestock and poultry with nonreactive growth promotion compound herbal medicine preparation, described Chinese medical extract obtains by following concentration and extraction process:
Step 1: take betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus by above-mentioned weight ratio;
Step 2: betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae that step 1 is taken are cleaned and impurities removing, get the drinking water of 2～3 times of the gross weight of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae are added in drinking water and soaked 5～7 hours, then 80～85 DEG C of decoctions of rear constant temperature 1～1.5 hour are boiled in heating, finally heating boil 30 minutes to liquid be heavily 1/8～1/12 of former amount of water, separate upper strata liquid and solid medicine slag blanket;
Step 3: step 2 gained upper strata liquid is put into concentration pan heating and be concentrated into heavily 1/4～1/5 the stiff paste for upper strata liquid, stiff paste density is about 1.38～1.40g/cm
3(70 DEG C);
Step 4: the solid medicine slag blanket of step 2 gained is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry dregs of a decoction that obtain after being dried;
Step 5: the dry dregs of a decoction that the Medicated Leaven taking in step 1, Fructus Hordei Germinatus are obtained with step 4 mix, and pulverize with pulverizer, obtaining particle diameter is 35～45 object meal;
Step 6: by the meal mix and blend in the stiff paste in step 3 and step 5, until become the Chinese medicine meal of even loose humidity;
Step 7: the Chinese medicine meal in step 6 is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry Chinese medicine meal obtaining after being dried;
Step 8: the Chinese medicine meal in step 7 is shattered with Chinese medicine fine powder machine, obtain 90～110 object micro-powder of Chinese herbs.
The present invention also provides the above-mentioned livestock and poultry application process of nonreactive growth promotion compound herbal medicine preparation in livestock and poultry cultivation, described livestock and poultry are added in the daily ration of livestock and poultry with nonreactive growth promotion compound herbal medicine preparation, and described livestock and poultry by the ratio of the daily ration of nonreactive growth promotion compound herbal medicine preparation and livestock and poultry are: in the daily ration of the livestock and poultry of 1000kg, add the livestock and poultry nonreactive growth promotion compound herbal medicine preparation described in 2～3kg
The present invention is improved on the basis of herbal medicine preparation " Pingwei San helps digestion " prescription, by adding appropriate enzyme preparation, polysaccharide, effective microorganism preparation and to pharmaceutical decocting piece through decoct, concentrated, meal, absorption, dry, the special process processing of micro mist etc., thoroughly change former prescription using dosage large, onset is slow, the course for the treatment of is long, the shortcoming that use cost is high, and expand the scope of application, be not only applicable to horse, ox, sheep, the domestic animals such as pig, can also be used for chicken, duck, goose, the birds such as dove are for control and the health care of disease of digestive system, and there is raising immunity clearly, effect of enhancing development.
The present invention adds the digestive ferment compositions such as protease, amylase, zytase, cellulase in former prescription on the one hand, strengthen the chemical digestion of stomach and intestine, make the nutriment in feed be able to thoroughly, digest fully, thereby improve the biological availability to feed, alleviate and be not fully absorbed the stench taste of the ight soil causing because of nutriment; Simultaneously due to the abundant digestion of nutriment, avoid product that protein digestibility is incomplete as stimulation and the murder by poisoning of amine to kidney, indirectly correct kidney swelling.Two aspect the present invention add the beneficial bacterium compositions such as bacillus subtilis, natto Bacillus, lichens brood cell bacterium in prescription, flora in balance intestines and stomach, make the profitable strain that participates in digestive function become dominant microflora, strengthen biological digestion and the removing toxic substances transformation function to harmful substance, alleviate the load of liver, indirectly impel the recovery of impaired liver function; Impel the ability of the synthetic vitamin of profitable strain, alleviate the hypovitaminosis causing owing to abusing antimicrobial, correct bio-digestion hypodynamia.The present invention adds yeast cell wall polysaccharide in prescription on the other hand, can efficient adsorption feed in bacterium and mycotoxin, significantly improve animal immunizing power, improve livestock and poultry production performance, reduce feedstuff-meat ratio, reduce the injury of harmful toxins to body.
What is more important, in prescription of the present invention, increase fuling peel composition, strengthen eliminating dampness and diuresis, effect of benefit spleen and stomach, in addition, increases Medicated Leaven and Fructus Hordei Germinatus, make it with Chinese medicine in each component carry out 5 and join, improve significantly the digestive function of animal, be particularly conducive to the recovery of the interior flora of enteron aisle and enzyme equilibrium, can greatly shorten the course for the treatment of of animal intestine gastric disease.Simultaneously each prepared slices of Chinese crude drugs by soaking, decoct, the technique such as concentrated, dry, absorption, ultramicro grinding, make each Effective Component of Chinese Medicine fully leach, fully carry out each other physical-chemical reaction, its absorptivity and bioavilability are significantly improved, and are the more than 5 times of ordinary powder.
The present invention is by above compatibility and process modification, cutting the end has solved the defect of former prescription, by adding this product 2～3kg in every 1000kg animal and fowl fodder, use second day with regard to visible ight soil moulding, the smelly ammonia taste of excrement alleviates, the increase of searching for food, the positive effect that defecation reduces, within 3～5 days, be can reach digesting and appetizing a course for the treatment of, regulate immunologic function, improve resistance against diseases, improve food conversion ratio, reduce diarrhea rate, reduce the ideal effect of ight soil ammonia stink, use every other week and just can meet or exceed the result of use of adding former prescription 10kg in the every 1000kg animal and fowl fodder of former prescription a course for the treatment of, use cost reduces more than 1 times than former prescription, and there is good promotion growth, improve effect of resistance against diseases, in the control of disease of digestive system, can use by substitute antibiotics completely.And antibiotic-free and growth promotion forbidden drug composition, drug residue free, has no drug resistance, and composite culture benefit is remarkable, meets the nonreactive cultivation policy that current China advocates completely, has good popularizing application prospect.
Detailed description of the invention
Below in conjunction with detailed description of the invention, technical scheme of the present invention is described in further detail, but does not form any limitation of the invention.
Embodiment 1
1, the preparation of micro-powder of Chinese herbs
Step 1.1: take betel nut 11.5kg, hawthorn 8Kg, rhizoma atractylodis 13.5kg, dried orange peel 14.8kg, fuling peel 15kg, bark of official magnolia 7.9kg, Radix Glycyrrhizae 6.8kg, Medicated Leaven 7.6kg, Fructus Hordei Germinatus 6.5kg;
Step 1.2: the betel nut taking, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae are cleaned and impurities removing is placed in 200kg drinking water and soaks 6 hours, then 80～85 DEG C of decoctions of rear constant temperature 1.5 hours are boiled in heating, finally heating is boiled 30 minutes until the upper strata liquid that can leach is 20 ± 1kg, separates upper strata liquid and solid medicine slag blanket;
Step 1.3: upper strata liquid is put into concentration pan heating and be concentrated into heavy 4.5 ± 0.5kg, obtain stiff paste, stiff paste density is about 1.38～1.40g/cm
3(70 DEG C);
Step 1.4: it is dry with 70～75 DEG C that solid medicine slag blanket is put into drying box, the water content of the dry dregs of a decoction that obtain after being dried needs≤8.0% weight portion;
Step 1.5: the dry dregs of a decoction that the Medicated Leaven taking in step 1.1, Fructus Hordei Germinatus are obtained with step 4 mix, and pulverize with pulverizer, obtaining particle diameter is 40 object meal;
Step 1.6: by the meal mix and blend in the stiff paste in step 1.3 and step 5, until become the Chinese medicine meal of even loose humidity;
Step 1.7: the Chinese medicine meal in step 1.6 is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry Chinese medicine meal obtaining after being dried;
Step 1.8: the Chinese medicine meal in step 1.7 is shattered with Chinese medicine fine powder machine, obtain 90～110 object micro-powder of Chinese herbs.
2, the preparation of nonreactive growth promotion compound herbal medicine preparation for livestock and poultry
Step 2.1: getting complex enzyme formulation is 2kg, micro-powder of Chinese herbs 2kg mixed 40 order stainless steel sifts, then claimed 4kg Chinese medicine fine powder to mix with mixture, crossed 40 order stainless steel sifts, and premixed is stand-by; Wherein, in every kg complex enzyme formulation, specifically comprise: zytase 2,200 ten thousand U, 1,4 beta-glucanase 7,500 ten thousand U, cellulase 1.25 hundred million U, pectase 500,000 U, amylase 2 500,000 U, protease 7,500,000 U.
Step 2.2: getting effective microorganism preparation is 4.5kg, and yeast cell wall polysaccharide is 4kg, and micro-powder of Chinese herbs is 8.5kg, mixes, and crosses 40 order stainless steel sifts, and premixed is stand-by; Wherein every kg effective microorganism preparation specifically comprises: bacillus subtilis >=15,000,000,000,000 cfu, lichens brood cell bacterium >=4.5 trillion cfu; Natto Bacillus >=2.5 trillion cfu.In every kg yeast cell wall polysaccharide, containing beta glucan is 200g, and manna oligosacchride is 200g;
Step 2.3: be that 79.5kg puts into three-dimensional mixer by the mixture obtaining in step 2.1, step 2.2 and micro-powder of Chinese herbs, mix about 15-20 minute, obtain lark, color uniformity, without conglomeration, without the uniform powder of color spot;
Step 2.4: step 2.3 gained uniform powder is carried out to the detections (asking inventor to provide examination criteria) such as moisture content, granularity, discriminating on request, carry out on request packing after qualified, sealing, vanning, warehouse entry.
Obtain sample 1.
Examination criteria:
1. moisture content is measured according to aquametry (60 pages of two annex of Chinese veterinary pharmacopoeia version in 2010), must not surpass 10%;
2. granularity: measuring according to granulometry (81 pages of two annex of Chinese veterinary pharmacopoeia version in 2010), is all that 0.42mm analyzes sieve by aperture, aperture is that 0.25mm analysis sieve oversize must not be greater than 10%;
3. this product is got in discriminating (1), puts micro-Microscopic observation: endosperm fragment is colourless, and wall is thicker, has more great similar round pit.Pericarp lithocyte lilac red, redness or yellowish-brown, similar round or polygonal, diameter to 125 μ m.Needle-like calcium oxalate crystal is tiny, and long 5～32 μ m, are filled in parenchyma cell brokenly.Lithocyte is branched, wall thickness, and laminated striation is obvious.Fibre bundle around parenchyma cell, containing calcium oxalate prismatic crystal, forms crystal fiber.Calcium oxalate prismatic crystal is present in parenchymal tissue in flakes.
Embodiment 2:
The preparation method of the present embodiment and embodiment 1 is identical with formula, and different places are,
In every kg complex enzyme formulation, specifically comprise: zytase 2,200 ten thousand U, 1,4 beta-glucanase 7,500 ten thousand U, cellulase 1.25 hundred million U.
Embodiment 3:
The preparation method of the present embodiment and embodiment 1 is identical with formula, and different places are,
In every kg complex enzyme formulation, specifically comprise: zytase 2,200 ten thousand U, 1,4 beta-glucanase 7,500 ten thousand U, cellulase 1.25 hundred million U, pectase 500,000 U, amylase 2 500,000 U.
Embodiment 4:
The preparation method of the present embodiment and embodiment 1 is identical with formula, and different places are,
Every kg effective microorganism preparation specifically comprises: bacillus subtilis >=15,000,000,000,000 cfu, lichens brood cell bacterium >=4.5 trillion cfu.
Embodiment 5:
The present embodiment is identical with formula with the preparation method of embodiment 1, different places are, the each Chinese medicine weight taking in step 1.1 is: betel nut 10.8kg, hawthorn 8.9kg, rhizoma atractylodis 12.2kg, dried orange peel 14.5kg, fuling peel 15.6kg, bark of official magnolia 7.5kg, Radix Glycyrrhizae 6.9kg, Medicated Leaven 7.0kg, Fructus Hordei Germinatus 6.4kg.
Embodiment 6:
The present embodiment is identical with formula with the preparation method of embodiment 1, different places are, the each Chinese medicine weight taking in step 1.1 is: betel nut 11.9kg, hawthorn 7.7kg, rhizoma atractylodis 14.7kg, dried orange peel 12.7kg, fuling peel 12.2kg, bark of official magnolia 8.9kg, Radix Glycyrrhizae 6.2kg, Medicated Leaven 7.9kg, Fructus Hordei Germinatus 7.0kg.
Embodiment 7:
The present embodiment is identical with formula with the preparation method of embodiment 6, and different places are, the complex enzyme formulation 1.5kg, the micro-powder of Chinese herbs 1.5kg that in step 2.1, take; Effective microorganism preparation 4.2kg, the yeast cell wall polysaccharide 4.3kg and the micro-powder of Chinese herbs 8.5kg that in step 2.2, take; The micro-powder of Chinese herbs taking in step 2.3 is 79kg.
Comparative example 1
Preparation contrast sample 1.
By two of Chinese veterinary pharmacopoeia versions in 2010---the Pingwei San standard that helps digestion, takes betel nut 14kg, hawthorn 33kg, rhizoma atractylodis 16kg, dried orange peel 18kg, bark of official magnolia 11kg, Radix Glycyrrhizae 8kg.With extremely about 20-24 order of Chinese medicine coarse-cracking machine meal, then use Chinese medicine fine powder machine fine powder to about 40-60 order, cross 40 order stainless steel sifts, put into three-dimensional mixer, mix about 15-20 minute, obtain lark, color uniformity, without conglomeration, without the uniform powder of color spot;
Must contrast sample 1
Animal feeding embodiment 1
The impact of sample 1 on meat chicken production performance.
1, materials and methods
(1) material
Get the sample 1 of above-described embodiment 1 and contrast the test material of sample 1 (Pingwei San helps digestion) as this animal feeding embodiment 1
(2) conceptual design
The unified raising after one week of the fast large yellow-feather broiler of Wen Shi of 1 age in days, randomly draws 900, is divided into 3 groups, every group of 3 repetitions, and 100 of each repetitions, point experiment I group, experiment II group, blank group, and take initial body weight; Experiment I group is used sample 1 by feed mixing, and experiment II group is used contrast sample 1 by feed mixing, and blank group need not any medicated premix.The experiment I group sample 1 of feeding, 2.5kg sample 1 is mixed particulate material 1000kg, the sample 1 three days of feeding continuously every other week; Experiment II group is fed and is contrasted sample 1, and 10kg contrast sample 1 is mixed particulate material 1000kg, feeds continuously every other week and contrasts sample 1 three days; The blank group normal chicken particulate material of feeding.Experimental group and blank group all adopt and raise in cages, free choice feeding drinking-water, three groups, pellet is identical, record broiler chicken daily feed intake, regularly carry out immunity and cleaning hen house, after 3 hours, weigh on an empty stomach taking group as unit weekly, during empty stomach, freely drink water, breeding cycle is 35 days, calculates each stage average daily gain, average daily ingestion amount, feedstuff-meat ratio and survival rate.The concrete formula of pellet is corn 55.3%, dregs of beans 36%, calcium monohydrogen phosphate 1.8%, stone flour 1%, fat oil 1.4%, fish meal 2.5%, premix 2%.
2, result and data
2.1 growth performances are measured:
The initial average weight of 7 age in days: only, only, blank group 100.8g/ only for experiment II group 101.3g/ for experiment I group 100.5g/.
Table one:
Result of the test shows:
Livestock and poultry of the present invention feed to raise to test by every 1000kg feed interpolation 2.5kg with nonreactive growth promotion compound herbal medicine preparation and show, its food digesting stomach fortifying, aid digestion, growth promotion, raising daily gain, reduce feedstuff-meat ratio, improve the effect that every production performance indexs such as survival rate are all obviously better than every 1000kg feed and add 10kg " Pingwei San helps digestion ", not only significantly improve the growth performance of broiler chicken, can also significantly improve the resistance against diseases of broiler chicken; It is that column home does not have ammonia stink substantially that the livestock and poultry of the present invention nonreactive of feeding growth promotion compound herbal medicine preparation experimental group and contrast groups are the most significantly distinguished, chicken manure is dried slivering, substantially there is not intestines problem, and feather light is glossy, the entirety speed of growth is comparatively average, using dosage is only 1/4th of contrast groups, and use cost reduces more than 1 times than contrast groups.
Animal feeding embodiment 2
The prevention effect of sample 1 to ternary intestine of young pigs disease.
1, materials and methods
(1) material
Get the sample 1 of above-described embodiment 1 and contrast the test material of sample 1 (Pingwei San helps digestion) as this animal feeding embodiment 2.
(2) conceptual design
Subjects is that source is consistent, same parity, the farrowing time is close, litter size is identical, and sex ratio is close, weight of weaning litter, the Du great Chang ternary weanling pig that body weight is close, be divided into and test I group, test totally 3 groups of II group and blank groups by paired experiment principle, every group of 3 repetitions, 20 of each repetitions, totally 180.Experiment I initial counterpoise of group (10.21 ± 1.25) kg, experiment II initial counterpoise of group (10.12 ± 1.25) kg, initial counterpoise of blank group (10.18 ± 1.25) kg, the experiment I group sample 1 of feeding, feeds 3 days week about; Experiment II group is fed and is contrasted sample 1, feeds week about 3 days; Blank group is not additionally added any medicated premix.2.5kg sample 1 mix fodder 1000kg, 10kg contrast sample 1 mix fodder 1000kg, allows the piglet free choice feeding, the cycle of feeding be 50 days.Experimental group and the blank group particulate material of all throwing something and feeding four times every day, regularly cleans pig house during this time, and vaccine program vaccinate.The concrete formula of particulate material is corn 54%, fine rice bran 5.94%, high-quality fish meal 5%, dregs of beans 31%, calcium monohydrogen phosphate 1.2%, stone flour 0.7%, salt 0.16%, premix 2.0%.
In 50 days, record the diarrhoea frequency of control group and experimental group.
2, result and data
Table two:
| ? | Experiment I group | Experiment II group | Blank group |
| Initial average weight kg | 10.21 | 10.12 | 10.18 |
| Average weight kg after 50 days | 42.71 | 40.62 | 37.18 |
| Incidence of Diarrhea | 3.33％ | 8.33％ | 36.67％ |
| The death rate | 0％ | 1.67％ | 11.67％ |
| Daily gain g/ days | 650 | 610 | 540 |
Result of the test shows:
Livestock and poultry of the present invention feed to raise to test by every 1000kg feed interpolation 2.5kg with nonreactive growth promotion compound herbal medicine preparation and show, its digesting and appetizing, adjusting immunologic function, the resistance against diseases that improves, raising daily gain, the effect that every growth performance index such as diarrhea rate, the minimizing death rate is all obviously better than every 1000kg feed interpolation 10kg " Pingwei San helps digestion " that reduces, not only significantly improve the growth performance of piglet, can also significantly reduce the incidence of intestine of young pigs disease and improve resistance against diseases.It is that pig house does not have ammonia stink substantially that the livestock and poultry of the present invention nonreactive of feeding growth promotion compound herbal medicine preparation experimental group and contrast groups are the most significantly distinguished, pig manure is comparatively dried, measures little, color depth, intestines problem significantly reduces, occur once in a while also very easily to recover, and the red hair of skin is bright, can eat and can sleep, the overall speed of growth is comparatively average, using dosage is only 1/4th of contrast groups, and use cost reduces more than 1 times than contrast groups.
Animal feeding embodiment 3
The result for the treatment of of sample 1 to Intestine of Broiler disease.
1, materials and methods
(1) material
Get the sample 1 and " Pingwei San helps digestion " test material as this animal feeding embodiment 3 of above-described embodiment 1
(2) conceptual design
The unified raising after three weeks of the fast large yellow-feather broiler of Wen Shi of 1 age in days, randomly draws 900, is divided into 3 groups, every group of 3 repetitions, and 100 of each repetitions, point experiment I group, experiment II group, blank group, and claim initial average weight; Select mouldy pellet, the concrete content of the mark of this pellet is corn 55.3%, dregs of beans 38%, calcium monohydrogen phosphate 1.4%, stone flour 1%, salt 0.3%, oil 3%, premix 1%.Feed continuously 2 days above-mentioned mouldy pellets, free choice feeding drinking-water, feeds 2 days, records the quantity that does not digest the sick chicken that feed is many in lassitude, ight soil jaundice, ight soil.Within the 3rd day, rise to feed and raise normally not mouldy pellet, formula is with mouldy pellet is identical before, experiment I group is used sample 1 by feed mixing, experiment II group is used contrast sample 1 by feed mixing, blank group need not any medicated premix, 2.5kg sample 1 mix fodder 1000kg, 10kg contrast sample 1 mix fodder 1000kg, free choice feeding drinking-water, feed continuously 7 days, record the quantity of disease chicken every day, continue record 7 days, after 7 days, after 3 hours, weigh on an empty stomach taking group as unit, during empty stomach, freely drink water.
2, result and data
Table three
| ? | Experiment I group | Experiment II group | Blank group |
| Initial average weight (g) | 445.6 | 450.2 | 443.3 |
| Average weight after 7 days (g) | 550.5 | 512.3 | 467.8 |
| (only) on the 1st | 255 | 256 | 255 |
| (only) on the 2nd | 252 | 254 | 258 |
| (only) on the 3rd | 156 | 243 | 258 |
| (only) on the 4th | 86 | 189 | 243 |
| (only) on the 5th | 32 | 126 | 220 |
| (only) on the 6th | 8 | 82 | 189 |
| (only) on the 7th | 2 | 67 | 182 |
Result of the test shows:
Livestock and poultry of the present invention are raised experiment with nonreactive growth promotion compound herbal medicine preparation by feeding of every 1000kg feed interpolation 2.5kg and show; the effect that every growth performance indexs such as its digesting and appetizing, absorbing mycotoxin, adjusting immunologic function, the resistance against diseases that improves, protection function of intestinal canal, reduction diarrhea rate, the minimizing death rate are all obviously better than every 1000kg feed adds 10kg " Pingwei San helps digestion "; not only significantly improve the resistivity of broiler chicken to harmful substances such as mycotoxins, can also significantly reduce the incidence of Intestine of Broiler disease and improve resistance against diseases.It is that within the 3rd day, to play chicken manure be obvious drying and moulding that the livestock and poultry of the present invention nonreactive of feeding growth promotion compound herbal medicine preparation experimental group and contrast groups are the most significantly distinguished, color is by the rare Dark grey spiral shell meat shape that just turns of yellow, most of chicken spirit and appetite are all recovered substantially, the growth performances such as daily gain recover rapidly, and using dosage is only 1/4th of contrast groups, use cost reduces more than 1 times than contrast groups.
Above-described is only preferred embodiment of the present invention, all any amendments of doing within the scope of the spirit and principles in the present invention, is equal to and replaces and improvement etc., within all should being included in protection scope of the present invention.
Claims (9)
1. a nonreactive growth promotion compound herbal medicine preparation for livestock and poultry, it is characterized in that, formed by complex enzyme formulation, effective microorganism preparation, yeast cell wall polysaccharide and micro-powder of Chinese herbs, the weight portion of described complex enzyme formulation, effective microorganism preparation, yeast cell wall polysaccharide and micro-powder of Chinese herbs is respectively 1.5～2.5 parts, 4～5 parts, 3.5～4.5 parts, 88～91 parts; Described micro-powder of Chinese herbs be betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus through decocting, the mixture of concentrated, meal, absorption, dry, micro mist PROCESS FOR TREATMENT, the weight ratio of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus is 10～12:7.5～9:12～15:16～12:16～12:7.5～9:6～7:7～8:6～7.
2. nonreactive growth promotion compound herbal medicine preparation for livestock and poultry according to claim 1, is characterized in that, described complex enzyme formulation is the combination of at least two kinds in zytase, 1,4 beta-glucanase, cellulase, pectase, amylase, protease.
3. nonreactive growth promotion compound herbal medicine preparation for livestock and poultry according to claim 1, is characterized in that, described effective microorganism preparation is at least one or the multiple combination in bacillus subtilis, lichens brood cell bacterium, natto Bacillus.
4. nonreactive growth promotion compound herbal medicine preparation for livestock and poultry according to claim 1, is characterized in that, described micro-powder of Chinese herbs obtains by following steps:
Step 1: take betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus by weight ratio claimed in claim 1;
Step 2: betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae that step 1 is taken are cleaned and impurities removing, get the drinking water of 2～3 times of the gross weight of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae are added in drinking water and soaked 5～7 hours, then 80～85 DEG C of decoctions of rear constant temperature 1～1.5 hour are boiled in heating, finally heating boil 30 minutes to liquid be heavily 1/8～1/12 of former amount of water, separate upper strata liquid and solid medicine slag blanket;
Step 3: step 2 gained upper strata liquid is put into concentration pan heating and be concentrated into heavily 1/4～1/5 the stiff paste for upper strata liquid, stiff paste density is 1.38～1.40g/cm
3;
Step 4: the solid medicine slag blanket of step 2 gained is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry dregs of a decoction that obtain after being dried;
Step 5: the dry dregs of a decoction that the Medicated Leaven taking in step 1, Fructus Hordei Germinatus are obtained with step 4 mix, and pulverize with pulverizer, obtaining particle diameter is 35～45 object meal;
Step 6: by the meal mix and blend in the stiff paste in step 3 and step 5, until become the Chinese medicine meal of even loose humidity;
Step 7: the Chinese medicine meal in step 6 is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry Chinese medicine meal obtaining after being dried;
Step 8: the Chinese medicine meal in step 7 is shattered with Chinese medicine fine powder machine, obtain 90～110 object micro-powder of Chinese herbs.
5. a preparation method for nonreactive growth promotion compound herbal medicine preparation for livestock and poultry as claimed in claim 1, is characterized in that,
Step 1: take complex enzyme and the mixing of equivalent micro-powder of Chinese herbs by weight ratio claimed in claim 1, cross 40 order stainless steel sifts, then take the mixing of mixture equivalent micro-powder of Chinese herbs, cross 40 order stainless steel sifts, premixed, stand-by;
Step 2: take effective microorganism preparation, yeast cell wall polysaccharide and equivalent micro-powder of Chinese herbs by weight ratio claimed in claim 1 and mix, cross 40 order stainless steel sifts, premixed, stand-by;
Step 3: step 1 mixture, step 2 mixture and take by weight remaining Chinese medicine fine powder, put into three-dimensional mixer, mix about 15-20 minute, obtain lark, color uniformity, without conglomeration, without the uniform powder of color spot;
Step 4: step 2 gained mixture is carried out to the detections such as moisture content, granularity, discriminating on request, carry out on request packing after qualified, sealing, vanning, warehouse entry.
6. the preparation method of nonreactive growth promotion compound herbal medicine preparation for livestock and poultry according to claim 5, it is characterized in that, described complex enzyme formulation is the combination of at least two kinds in zytase, 1,4 beta-glucanase, cellulase, pectase, amylase, protease.
7. the preparation method of nonreactive growth promotion compound herbal medicine preparation for livestock and poultry according to claim 5, is characterized in that, described effective microorganism preparation is one or more in bacillus subtilis, natto Bacillus, lichens brood cell bacterium.
8. the preparation method of nonreactive growth promotion compound herbal medicine preparation for livestock and poultry according to claim 5, is characterized in that, described Chinese medical extract obtains by following concentration and extraction process:
Step 1: take betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, Medicated Leaven, Fructus Hordei Germinatus by weight ratio claimed in claim 1;
Step 2: betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae that step 1 is taken are cleaned and impurities removing, get the drinking water of 2～3 times of the gross weight of described betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae, betel nut, hawthorn, rhizoma atractylodis, dried orange peel, fuling peel, the bark of official magnolia, Radix Glycyrrhizae are added in drinking water and soaked 5～7 hours, then 80～85 DEG C of decoctions of rear constant temperature 1～1.5 hour are boiled in heating, finally heating boil 30 minutes to liquid be heavily 1/8～1/12 of former amount of water, separate upper strata liquid and solid medicine slag blanket;
Step 3: step 2 gained upper strata liquid is put into concentration pan heating and be concentrated into heavily 1/4～1/5 the stiff paste for upper strata liquid, stiff paste density is 1.38～1.40g/cm
3;
Step 4: the solid medicine slag blanket of step 2 gained is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry dregs of a decoction that obtain after being dried;
Step 5: the dry dregs of a decoction that the Medicated Leaven taking in step 1, Fructus Hordei Germinatus are obtained with step 4 mix, and pulverize with pulverizer, obtaining particle diameter is 35～45 object meal;
Step 6: by the meal mix and blend in the stiff paste in step 3 and step 5, until become the Chinese medicine meal of even loose humidity;
Step 7: the Chinese medicine meal in step 6 is put into drying box dry with 70～75 DEG C, water content≤8.0% weight portion of the dry Chinese medicine meal obtaining after being dried;
Step 8: the Chinese medicine meal in step 7 is shattered with Chinese medicine fine powder machine, obtain 90～110 object micro-powder of Chinese herbs.
9. livestock and poultry as claimed in claim 1 application in livestock and poultry cultivation with nonreactive growth promotion compound herbal medicine preparation, described livestock and poultry are added in the daily ration of livestock and poultry with nonreactive growth promotion compound herbal medicine preparation, and described livestock and poultry by the ratio of the daily ration of nonreactive growth promotion compound herbal medicine preparation and livestock and poultry are: in the daily ration of the livestock and poultry of 1000kg, add the livestock and poultry nonreactive growth promotion compound herbal medicine preparation described in 2-3kg.
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