CN103977329A - Traditional Chinese medicine liquid for treating pregnancy hypertension and preparation method thereof - Google Patents
Traditional Chinese medicine liquid for treating pregnancy hypertension and preparation method thereof Download PDFInfo
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Abstract
The invention discloses traditional Chinese medicine liquid for treating pregnancy hypertension and a preparation method of the medicine liquid and belongs to the field of traditional Chinese medicines. The effective components of the traditional Chinese medicine liquid comprise the following raw materials: corydalis saxicola, horseradish, lignum dalbergiae odoriferae, rhizoma galangae, the root of kudzu vine, cyrtomium fortune, the fruit of Chinese wolfberry, euphorbia kansui, sticktight, cherokee rose, lotus leaf, semen cassia, orchis, indian rorippa herb, buckwheat and seed of feather cockscomb. The traditional Chinese medicine liquid is reasonable in compatibility of medicines, meets the theory of traditional Chinese medicine and modern medicine, has the functions of tonifying spleen and alleviating water retention, strengthening the heart and tonifying kidney as well as tonifying lung and regulating qi, has the characteristics of good curative effect and high safety in treatment on pregnancy hypertension and is convenient to take, free of toxic and side effect, free of influence on fetal development, remarkable in curative effect, low in cost and worthy to be widely popularized and used in clinic.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine liquid medicine and preparation method for the treatment of preeclampsia.
Background technology
Preeclampsia, i.e. said hypertensive state of pregnancy, preeclampsias etc. in the past, are the distinctive diseases of anemia of pregnant woman, majority occurs in gestation 20 weeks and two weeks puerperal, accounts for all anemia of pregnant woman's 5%.Wherein a part also occurs with albuminuria or edema, and be referred to as pregnancy-hypertension syndrome, the person of being in a bad way can produce the symptoms such as headache, blurred vision, upper abdominal pain, if not suitably treatment may cause that general spasm even goes into a coma.The pathological change of primary disease is mainly whole body arteriolospasm; Pathological changes can be involved multiple organs, when serious, can cause major organs anoxia, edema, the necrosis such as the heart, liver, kidney, brain, even nonfunction.Some patients were also can be left over the sequela such as chronic hypertension and nephropathy.
Preeclampsia is one of major reason causing anemia of pregnant woman's death.According to statistics, national preeclampsia Epidemiological study in 1988, at the 6.7 preeclampsia sickness rate 94% in anemia of pregnant woman of dying of dieing ten thousand deaths.Anemia of pregnant woman suffers from dead 46.9 people of every 100,000 people of preeclampsia, and perinatal stage is 16.6 ‰.As can be seen here, preeclampsia is the most dangerous disease of trimester of pregnancy.Because the cause of disease of pregnancy induced hypertension syndrome is not very clear and definite, so not all pregnancy induced hypertension syndrome can relief of symptoms by magnesium sulfate spasmolytic, now in order to prevent that the complication such as cerebrovascular accident, placental abruption from occurring, need to use antihypertensive drugs to carry out dilatation, though but antihypertensive drugs can make blood pressure drops, but reduce important organ blood flow, particularly uteroplacental blood flow, has certain harm to fetus simultaneously.
Western medical treatment method is mainly treated preeclampsia with blood pressure lowering, diuresis, calmness at present, because Western medicine side effect is large, can affect the development growth of fetus, and What is more, causes strange tire, stillborn fetus, causes great psychology and mental disorder to patient.
Summary of the invention
The invention provides a kind of Chinese medicine liquid medicine and preparation method for the treatment of preeclampsia; The selected medical material compatibility of Chinese medicine liquid medicine of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect that spleen reinforcing diuretic, heart tonifying the kidney invigorating, lung benefiting are regulated the flow of vital energy, aspect treatment preeclampsia, there is good effect and the higher feature of safety, taking convenience, without any side effects, do not affect the growth of fetus, evident in efficacy, with low cost, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine liquid medicine for preeclampsia, raw material composition and the parts by weight of making described Chinese medicine liquid medicine effective ingredient are:
25～49 parts of 25～49 portions of Rhizoma Alpiniae Officinarums of 26～50 parts of Lignum Dalbergiae Odoriferaes of 28～52 parts of Wasabia japonic (Euterma Wasabi)s of Herba Corydalis tomentellae
22～46 parts of 23～47 parts of Radix Kansuis of 23～47 parts of Fructus Lycii of 24～48 parts of Rhizoma Osmundae of Radix Puerariae
19～43 parts of 19～43 parts of Semen Cassiaes of 20～44 parts of Folium Nelumbinis of 22～46 parts of Flos Rosae Laevigataes of Herba Bidentis Bipinnatae
13～37 parts of 16～40 parts of Semen Celosiae of 16～40 portions of Semen Fagopyri Esculentis of Herba Orchidis Latifoliae 17～41 Fen Herba Rorippae.
Raw material composition and the parts by weight of making described Chinese medicine liquid medicine effective ingredient are:
29～45 parts of 29～45 portions of Rhizoma Alpiniae Officinarums of 30～46 parts of Lignum Dalbergiae Odoriferaes of 32～48 parts of Wasabia japonic (Euterma Wasabi)s of Herba Corydalis tomentellae
26～42 parts of 27～43 parts of Radix Kansuis of 27～43 parts of Fructus Lycii of 28～44 parts of Rhizoma Osmundae of Radix Puerariae
23～39 parts of 23～39 parts of Semen Cassiaes of 24～40 parts of Folium Nelumbinis of 26～42 parts of Flos Rosae Laevigataes of Herba Bidentis Bipinnatae
17～33 parts of 20～36 parts of Semen Celosiae of 20～36 portions of Semen Fagopyri Esculentis of Herba Orchidis Latifoliae 21～37 Fen Herba Rorippae.
Raw material composition and the parts by weight of making described Chinese medicine liquid medicine effective ingredient are:
33～41 parts of 33～41 portions of Rhizoma Alpiniae Officinarums of 34～42 parts of Lignum Dalbergiae Odoriferaes of 36～44 parts of Wasabia japonic (Euterma Wasabi)s of Herba Corydalis tomentellae
30～38 parts of 31～39 parts of Radix Kansuis of 31～39 parts of Fructus Lycii of 32～40 parts of Rhizoma Osmundae of Radix Puerariae
27～35 parts of 27～35 parts of Semen Cassiaes of 28～36 parts of Folium Nelumbinis of 30～38 parts of Flos Rosae Laevigataes of Herba Bidentis Bipinnatae
21～29 parts of 24～32 parts of Semen Celosiae of 24～32 portions of Semen Fagopyri Esculentis of Herba Orchidis Latifoliae 25～33 Fen Herba Rorippae.
Raw material composition and the parts by weight of making described Chinese medicine liquid medicine effective ingredient are:
37 parts of 37 portions of Rhizoma Alpiniae Officinarums of 38 parts of Lignum Dalbergiae Odoriferaes of 40 parts of Wasabia japonic (Euterma Wasabi)s of Herba Corydalis tomentellae
34 parts of 35 parts of Radix Kansuis of 35 parts of Fructus Lycii of 36 parts of Rhizoma Osmundae of Radix Puerariae
31 parts of 31 parts of Semen Cassiaes of 32 parts of Folium Nelumbinis of 34 parts of Flos Rosae Laevigataes of Herba Bidentis Bipinnatae
25 parts of 28 parts of Semen Celosiae of 28 portions of Semen Fagopyri Esculentis of Herba Orchidis Latifoliae 29 Fen Herba Rorippae.
A preparation method for the treatment of the Chinese medicine liquid medicine of preeclampsia, comprises following processing step:
(1) Herba Corydalis tomentellae and Fructus Lycii are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, for subsequent use;
(2) Wasabia japonic (Euterma Wasabi), Lignum Dalbergiae Odoriferae, Radix Puerariae and Rhizoma Osmundae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Rhizoma Alpiniae Officinarum, Radix Kansui, Flos Rosae Laevigatae, Semen Cassiae, Herba Orchidis Latifoliae, Herba Rorippae and Semen Celosiae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(4) Herba Bidentis Bipinnatae and Folium Nelumbinis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) Semen Fagopyri Esculenti is placed in pot, intense fire is fried to surface and is yellow and savory overflowing, and taking-up cools, and grinds into powder, crosses 200 order fine powders, for subsequent use;
(6) by above-mentioned steps (1)～(5) prepared filtrate, fine powder and juice mixed dissolution, then carry out refine extraction, make liquid medicine, obtain the Chinese medicine liquid medicine for the treatment of preeclampsia of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Corydalis tomentellae: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, cool the blood dissipate blood stasis.Main influenza, laryngopharynx swelling and pain, conjunctival congestion and pain of eye, hemoptysis, spits blood, gastric heat gastralgia, hypochondriac pain due to stagnation of liverQI, damp-heat dysentery, carbuncle sore tumefacting virus, treating swelling and pain by traumatic injury.
Wasabia japonic (Euterma Wasabi): acrid in the mouth, cold in nature.The lipoid and reducing blood pressure of dispelling, removing toxic substances regulating menstruation, helps digestion.Cure mainly rheumatism, hypertension, hyperlipidemia, dysmenorrhea or menoxenia, asthma, the malicious patient of middle fish Eriocheir sinensis.
Lignum Dalbergiae Odoriferae: acrid in the mouth, warm in nature, nontoxic; Return liver, spleen, lung, heart channel.Promoting blood circulation to remove blood stasis, hemostasis analgesic therapy, sending down the abnormal ascending QI, wards off dirty.Main pain in chest and hypochondrium, traumatic injury, wound hemorrhage, and the vomiting of colic of cold type pain or foul internal resistance stomachache." detailed outline " carries: " treat injured incised wound, hemostasis analgesic therapy, detumescence and promoting granulation.”
Rhizoma Alpiniae Officinarum: acrid in the mouth, hot in nature; Return spleen, stomach warp.Warming spleen and stomach for dispelling cold, regulating QI to relieve pain.Cure mainly coldness and pain in the epigastrium, vomiting, eructation.Modern medicine study confirmation, Rhizoma Alpiniae Officinarum water extract and ether extract have obvious choleretic effect and obvious analgesic activity.
Radix Puerariae: sweet in the mouth, pungent, property is flat; Enter spleen, stomach warp.Yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is temperature only.Typhoid fever, warm headache stiffness of the nape, dysphoria with smothery sensation is quenched one's thirst, has loose bowels, dysentery, skin eruption is not saturating, hypertension, angina pectoris, deafness." not Lu " carries: " the excessive cold invading middle-JIAO(the spleen and stomach) wind headache of curing the wound, expelling pathogenic factors from muscles, delivers, perspires, loosing the interspaces of skin and muscles.Treat incised wound, pain relieving, side of body wind pain.The juice of taking root, treatment is quenched one's thirst, typhoid fever high fever." modern medicine study, Radix Puerariae flavone has cancer-resisting and estrogen-like effects, can promote women's breast enlargement, skin care, especially obvious to middle-aged women and the effect of menopausal women face-nourishing health-care.
Rhizoma Osmundae: bitter in the mouth, puckery, cold nature, slightly poisonous; Return liver, stomach warp.Parasite killing, heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly anemopyretic cold, warm skin eruption, haematemesis hemoptysis, epistaxis is had blood in stool, metrorrhagia dysentery, leukorrhagia." Shaanxi Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, hemostasis parasite killing.The infectious disease such as prevention epidemic encephalitis type B, mumps.Treating hematochezia, hematuria, epistaxis, menorrhagia, ascariasis, pinworm disease.”
Fructus Lycii: sweet in the mouth, property are put down.Liver and kidney tonifying, nourishing blood for improving eyesight, anti-senility.Modern medicine study discovery, Fructus Lycii also has hepatoprotective and lipotropic effect.In Folium Lycii, fruit and root bark all containing abundant Folium hydrangeae strigosae alkali.Pharmacological evaluation shows, Folium hydrangeae strigosae alkali have suppress fat in hepatocyte deposition, promote the effect of liver cell regeneration.
Radix Kansui: bitter in the mouth, cold in nature, poisonous; Return spleen, lung, kidney, bladder, large intestine, small intestine meridian.Removing water retention by purgation is by swollen, dispersing swelling and dissipating binds.Cure mainly edema, ascites, prolonged fluid-retention blocked-up chest, epilepsy, breathes with cough, sphincter disturbance.
Herba Bidentis Bipinnatae: bitter in the mouth, cold nature; Return lung, spleen, stomach, large intestine channel.Heat-clearing and toxic substances removing, clearing away heat to cure dysentery, promoting blood circulation and stopping pain, for cold, fever, pharyngalgia, acute appendicitis, jaundice, malaria, venom, prurigo, traumatic injury, lumbago, arthralgia, stomachache, dysphagic, for diarrhoea, dysentery etc.Modern medicine study confirmation, Herba Bidentis Bipinnatae has replenishing QI to invigorate the spleen effect, can be used for body nihility power, diarrhea due to hypofunction of the spleen.
Flos Rosae Laevigatae: sour in the mouth, puckery, property is flat, nontoxic; Return lung, kidney, large intestine channel.Astringing intestine to stop diarrhea controlling nocturnal emission with astringent drugs, reducing urination leukorrhagia stopping, parasite killing.Main chronic diarrhea chronic dysentery, seminal emission, frequent micturition, leukorrhagia, cestode, ascarid, pinworm disease, early whitening of beard and hair." modern Practical Chinese medicinal " carries: " control seminal emission, the enuresis, frequent micturition, chronic diarrhea rushes down, and chronic weak property sweating due to debility goes out, and married woman's endometritis secretion leukorrhagia.”
Folium Nelumbinis: bitter in the mouth, property is flat; Return liver, spleen, stomach warp.Clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood is told nosebleed, the metrorrhagia of having blood in stool, blood pressure lowering, blood fat reducing.Modern study shows, Folium Nelumbinis has effect for reducing blood fat.
Semen Cassiae: sweet in the mouth, hardship, salty, cold nature; Return liver, large intestine channel.Clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " liver heat removing and eyesight improving, diuretic relieving constipation.Treating the liver inflammation, cirrhotic ascites, hypertension, infantile malnutrition, nyctalopia, wind heat ophthalmalgia, habitual constipation." modern medicine study confirmation, the infusion of Semen Cassiae has hypotensive effect.
Herba Orchidis Latifoliae: sweet in the mouth, property is flat; GUIXIN, kidney, stomach warp.Heart tonifying the kidney invigorating, promoting the production of body fluid to quench thirst, strengthening the spleen and stomach.Cure mainly agitation thirsty, anorexia, menoxenia, asthenia anemia, dizziness, dim eyesight." Inner Mongol Chinese herbal medicine " carries: " heart tonifying, the kidney invigorating are promoted the production of body fluid, and quench the thirst, and strengthening the spleen and stomach, controls agitation thirsty, anorexia, YIN-fluid being insufficient, menoxenia.”
Herba Rorippae: sweet in the mouth, light, cool in nature.Heat-clearing and toxic substances removing, antitussive diuresis.For cold, fever, laryngopharynx swelling and pain, cough due to lung-heat, chronic tracheitis, acute rheumatic arthritis, hepatitis, dysuria; Dermatitis rhus is controlled in external, venom, furuncle carbuncle.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.The heating that cures cold, laryngopharynx swelling and pain, aphonia; Cough due to lung-heat, hemoptysis; Acute rheumatic arthritis; Edema.”
Semen Fagopyri Esculenti: sweet in the mouth, flat, cold in nature; Enter spleen, stomach, large intestine channel.Stomach invigorating convergence, blood pressure lowering hemostasis.Be applicable to hypertension, blood capillary vulnerability is hemorrhage, prevents and treats apoplexy, retinal hemorrhage, pneumorrhagia; External convergence hidroschesis, antiinflammatory.
Semen Celosiae: bitter in the mouth, cold in nature; Return Liver Channel.The people's heat of dispelling, clearing away liver-fire, improving acuity of vision and removing nebula.Main conjunctival congestion and swelling pain, the nebula of looking unfamiliar film, blurring of vision, hypertension, epistaxis, skin wind heat pruritus, skin ulcer tinea." property of medicine opinion " carries: " the dirty pyretic toxicity dotting punch for the treatment of the liver, red barrier, optic atrohic blindness, nebula swell.Main malignant boil scabies scabies, controls the inferior portion worm and reveals skin ulcer.”
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of Chinese medicine liquid medicine of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect that spleen reinforcing diuretic, heart tonifying the kidney invigorating, lung benefiting are regulated the flow of vital energy, aspect treatment preeclampsia, there is good effect and the higher feature of safety, taking convenience, without any side effects, do not affect the growth of fetus, evident in efficacy, with low cost, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine liquid medicine effective ingredient of the present invention are:
Herba Corydalis tomentellae 48g Wasabia japonic (Euterma Wasabi) 46g Lignum Dalbergiae Odoriferae 45g Rhizoma Alpiniae Officinarum 45g
Radix Puerariae 44g Rhizoma Osmundae 43g Fructus Lycii 43g Radix Kansui 42g
Herba Bidentis Bipinnatae 42g Flos Rosae Laevigatae 40g Folium Nelumbinis 39g Semen Cassiae 39g
Herba Orchidis Latifoliae 37g Herba Rorippae 36g Semen Fagopyri Esculenti 36g Semen Celosiae 33g.
The preparation method of Chinese medicine liquid medicine of the present invention, comprises following processing step:
(1) Herba Corydalis tomentellae and Fructus Lycii are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, for subsequent use;
(2) Wasabia japonic (Euterma Wasabi), Lignum Dalbergiae Odoriferae, Radix Puerariae and Rhizoma Osmundae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Rhizoma Alpiniae Officinarum, Radix Kansui, Flos Rosae Laevigatae, Semen Cassiae, Herba Orchidis Latifoliae, Herba Rorippae and Semen Celosiae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(4) Herba Bidentis Bipinnatae and Folium Nelumbinis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) Semen Fagopyri Esculenti is placed in pot, intense fire is fried to surface and is yellow and savory overflowing, and taking-up cools, and grinds into powder, crosses 200 order fine powders, for subsequent use;
(6) by above-mentioned steps (1)～(5) prepared filtrate, fine powder and juice mixed dissolution, then carry out refine extraction, make liquid medicine, obtain the Chinese medicine liquid medicine for the treatment of preeclampsia of the present invention.
Usage and dosage: oral, every day 1 time, each 10 milliliters, one after each meal, 5 days is 1 course for the treatment of, and can fully recover 1～2 course for the treatment of, the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of Chinese medicine liquid medicine effective ingredient of the present invention are:
Herba Corydalis tomentellae 44g Wasabia japonic (Euterma Wasabi) 42g Lignum Dalbergiae Odoriferae 41g Rhizoma Alpiniae Officinarum 41g
Radix Puerariae 40g Rhizoma Osmundae 39g Fructus Lycii 39g Radix Kansui 38g
Herba Bidentis Bipinnatae 38g Flos Rosae Laevigatae 36g Folium Nelumbinis 35g Semen Cassiae 35g
Herba Orchidis Latifoliae 33g Herba Rorippae 32g Semen Fagopyri Esculenti 32g Semen Celosiae 29g.
Chinese medicine liquid medicine preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine liquid medicine effective ingredient of the present invention are:
Herba Corydalis tomentellae 40g Wasabia japonic (Euterma Wasabi) 38g Lignum Dalbergiae Odoriferae 37g Rhizoma Alpiniae Officinarum 37g
Radix Puerariae 36g Rhizoma Osmundae 35g Fructus Lycii 35g Radix Kansui 34g
Herba Bidentis Bipinnatae 34g Flos Rosae Laevigatae 32g Folium Nelumbinis 31g Semen Cassiae 31g
Herba Orchidis Latifoliae 29g Herba Rorippae 28g Semen Fagopyri Esculenti 28g Semen Celosiae 25g.
Chinese medicine liquid medicine preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine liquid medicine effective ingredient of the present invention are:
Herba Corydalis tomentellae 36g Wasabia japonic (Euterma Wasabi) 34g Lignum Dalbergiae Odoriferae 33g Rhizoma Alpiniae Officinarum 33g
Radix Puerariae 32g Rhizoma Osmundae 31g Fructus Lycii 31g Radix Kansui 30g
Herba Bidentis Bipinnatae 30g Flos Rosae Laevigatae 28g Folium Nelumbinis 27g Semen Cassiae 27g
Herba Orchidis Latifoliae 25g Herba Rorippae 24g Semen Fagopyri Esculenti 24g Semen Celosiae 21g.
Chinese medicine liquid medicine preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of Chinese medicine liquid medicine effective ingredient of the present invention are:
Herba Corydalis tomentellae 32g Wasabia japonic (Euterma Wasabi) 30g Lignum Dalbergiae Odoriferae 29g Rhizoma Alpiniae Officinarum 29g
Radix Puerariae 28g Rhizoma Osmundae 27g Fructus Lycii 27g Radix Kansui 26g
Herba Bidentis Bipinnatae 26g Flos Rosae Laevigatae 24g Folium Nelumbinis 23g Semen Cassiae 23g
Herba Orchidis Latifoliae 21g Herba Rorippae 20g Semen Fagopyri Esculenti 20g Semen Celosiae 17g.
Chinese medicine liquid medicine preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine liquid medicine for the treatment of preeclampsia, select the routine clinical observation of patients with pregnancy induced hypertention 176 of making a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group women's 88 examples, 20～37 years old age, 28.5 years old mean age, average course of disease 3 months at random; Matched group women 88 examples, 21～38 years old age, 29.5 years old mean age, average course of disease 2 months.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine liquid medicine of the present invention, usage and dosage: oral, every day 1 time, each 10 milliliters, one after each meal, 5 days is 1 course for the treatment of, and can fully recover 1～2 course for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken dexamethasone tablet, oral, one time 1～4,2～4 times on the one, sooner or later clothes after the meal; 1 of maintenance dose one time, 1 time on the one, the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: clinical symptoms all disappears, the each index of correlation of lab testing recovers normal.
(2) effective: clinical symptoms obviously alleviates, test chamber checks that each index of correlation obviously improves, and sign is obviously kind.
(3) effective: clinical symptoms alleviates to some extent, and test chamber checks that each index of correlation makes moderate progress, and sign makes moderate progress.
(4) invalid: by treating rear clinical symptoms without alleviating or increasing the weight of.
4, result:
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, history, female, 25 years old, Shandong Zibo people.Existing pregnant 36 weeks of patient, headache, dizzy, poor sleep, blood pressure 160/110mmHg, 36.6 DEG C of body temperature, be diagnosed as preeclampsia, through using Chinese medicine liquid medicine treatment of the present invention, take after 1 course for the treatment of, symptom is alleviated to some extent, continue to take after 1 course for the treatment of transference cure, recovery from illness.
2, turn round and look at certain, female, 30 years old, jiangsu wuxi people.There is preeclampsia later stage of pregnancy in patient, blood pressure is undesired, used multiple Drug therapy, have no any improvement, recommend through doctor, take Chinese medicine liquid medicine treatment of the present invention, take after 1 course for the treatment of, symptom alleviates to some extent, take after 2 courses for the treatment of, transference cure, it is normal that blood pressure recovers, recovery from illness, after follow up a case by regular visits to without the generation of any bad phenomenon.
3, marquis, female, 26 years old, Anqing people.Patient's last year, conceived 24 weekly checks were found preeclampsia, urine protein is +++, there is the following edema of knee, after hospitalization, develop complications, give Chinese medicine liquid medicine treatment of the present invention, inject after 1 course for the treatment of, symptom is alleviated to some extent, injects after 2 courses for the treatment of transference cure, recovery from illness, followed up a case by regular visits to without any discomfort phenomenon after 2 months.
4, Shao, female, 28 years old, Nanping, Fujian people.The conceived 37+ of patient, produces inspection to hospital, finds that foot and shank begin to swell out, survey routine urinalysis, one, protein adds, blood pressure 113/70, doctor is diagnosed as preeclampsia, and doctor gives Chinese medicine liquid medicine treatment of the present invention, takes after 1 course for the treatment of, symptom obviously alleviates, take after 2 courses for the treatment of, transference cure, it is normal that blood pressure recovers, recovery from illness,, follow up a case by regular visits to without the generation of any bad phenomenon.
5, the Meng, female, 27 years old, people from Yichang.Patient's lower limb is swollen, nausea and vomiting, and epigastrium pain; oliguria, dripping, breathe hard; aphonia, sometimes two handss are wanted to jerk, and remove hospital admission; be diagnosed as preeclampsia, give Chinese medicine liquid medicine treatment of the present invention, inject after 1 course for the treatment of; symptom is obviously alleviated, and inject after 2 courses for the treatment of transference cure; recovery from illness, follow up a case by regular visits to without recurrence after 1 month.
6, dragon certain, female, 32 years old, people from Yulin.Patient's hydrosarca, headache, feeling of fullness in the head, blurred vision, goes obstetrics and gynecology hospital inspection, and check result is preeclampsia, recommend through doctor, take Chinese medicine liquid medicine treatment of the present invention, take after 1 course for the treatment of, symptom alleviates to some extent, take after 2 courses for the treatment of, transference cure, physical recovery is normal, recovery from illness.
Claims (5)
1. a Chinese medicine liquid medicine for the treatment of preeclampsia, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine liquid medicine effective ingredient are:
25～49 parts of 25～49 portions of Rhizoma Alpiniae Officinarums of 26～50 parts of Lignum Dalbergiae Odoriferaes of 28～52 parts of Wasabia japonic (Euterma Wasabi)s of Herba Corydalis tomentellae
22～46 parts of 23～47 parts of Radix Kansuis of 23～47 parts of Fructus Lycii of 24～48 parts of Rhizoma Osmundae of Radix Puerariae
19～43 parts of 19～43 parts of Semen Cassiaes of 20～44 parts of Folium Nelumbinis of 22～46 parts of Flos Rosae Laevigataes of Herba Bidentis Bipinnatae
13～37 parts of 16～40 parts of Semen Celosiae of 16～40 portions of Semen Fagopyri Esculentis of Herba Orchidis Latifoliae 17～41 Fen Herba Rorippae.
2. a kind of Chinese medicine liquid medicine for the treatment of preeclampsia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine liquid medicine effective ingredient are:
29～45 parts of 29～45 portions of Rhizoma Alpiniae Officinarums of 30～46 parts of Lignum Dalbergiae Odoriferaes of 32～48 parts of Wasabia japonic (Euterma Wasabi)s of Herba Corydalis tomentellae
26～42 parts of 27～43 parts of Radix Kansuis of 27～43 parts of Fructus Lycii of 28～44 parts of Rhizoma Osmundae of Radix Puerariae
23～39 parts of 23～39 parts of Semen Cassiaes of 24～40 parts of Folium Nelumbinis of 26～42 parts of Flos Rosae Laevigataes of Herba Bidentis Bipinnatae
17～33 parts of 20～36 parts of Semen Celosiae of 20～36 portions of Semen Fagopyri Esculentis of Herba Orchidis Latifoliae 21～37 Fen Herba Rorippae.
3. a kind of Chinese medicine liquid medicine for the treatment of preeclampsia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine liquid medicine effective ingredient are:
33～41 parts of 33～41 portions of Rhizoma Alpiniae Officinarums of 34～42 parts of Lignum Dalbergiae Odoriferaes of 36～44 parts of Wasabia japonic (Euterma Wasabi)s of Herba Corydalis tomentellae
30～38 parts of 31～39 parts of Radix Kansuis of 31～39 parts of Fructus Lycii of 32～40 parts of Rhizoma Osmundae of Radix Puerariae
27～35 parts of 27～35 parts of Semen Cassiaes of 28～36 parts of Folium Nelumbinis of 30～38 parts of Flos Rosae Laevigataes of Herba Bidentis Bipinnatae
21～29 parts of 24～32 parts of Semen Celosiae of 24～32 portions of Semen Fagopyri Esculentis of Herba Orchidis Latifoliae 25～33 Fen Herba Rorippae.
4. a kind of Chinese medicine liquid medicine for the treatment of preeclampsia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine liquid medicine effective ingredient are:
37 parts of 37 portions of Rhizoma Alpiniae Officinarums of 38 parts of Lignum Dalbergiae Odoriferaes of 40 parts of Wasabia japonic (Euterma Wasabi)s of Herba Corydalis tomentellae
34 parts of 35 parts of Radix Kansuis of 35 parts of Fructus Lycii of 36 parts of Rhizoma Osmundae of Radix Puerariae
31 parts of 31 parts of Semen Cassiaes of 32 parts of Folium Nelumbinis of 34 parts of Flos Rosae Laevigataes of Herba Bidentis Bipinnatae
25 parts of 28 parts of Semen Celosiae of 28 portions of Semen Fagopyri Esculentis of Herba Orchidis Latifoliae 29 Fen Herba Rorippae.
5. a preparation method for the treatment of the Chinese medicine liquid medicine of preeclampsia as described in claim 1～4 any one, is characterized in that: comprise following processing step:
(1) Herba Corydalis tomentellae and Fructus Lycii are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, for subsequent use;
(2) Wasabia japonic (Euterma Wasabi), Lignum Dalbergiae Odoriferae, Radix Puerariae and Rhizoma Osmundae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Rhizoma Alpiniae Officinarum, Radix Kansui, Flos Rosae Laevigatae, Semen Cassiae, Herba Orchidis Latifoliae, Herba Rorippae and Semen Celosiae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(4) Herba Bidentis Bipinnatae and Folium Nelumbinis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) Semen Fagopyri Esculenti is placed in pot, intense fire is fried to surface and is yellow and savory overflowing, and taking-up cools, and grinds into powder, crosses 200 order fine powders, for subsequent use;
(6) by above-mentioned steps (1)～(5) prepared filtrate, fine powder and juice mixed dissolution, then carry out refine extraction, make liquid medicine, obtain the Chinese medicine liquid medicine for the treatment of preeclampsia of the present invention.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105535847A (en) * | 2016-01-19 | 2016-05-04 | 青岛大学附属医院 | Traditional Chinese medicine decoction for treating pregnancy hypertension postnatal proteinuria |
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