CN102552685B - Traditional Chinese medicine decoction for treating insomnia - Google Patents
Traditional Chinese medicine decoction for treating insomnia Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine decoction for treating insomnia, which is prepared by the following raw material herbs by weight: 30-50 g of radix rehmanniae preparata, 15-20 g of epimeddium, 20-30 g of polygonatum rhizome, 10-20 g of ligustrum lucidum, 5-10 g of Chinese magnoliavine, 20-30 g of white peony roots, 20-30 g of spine date seeds, 20-30 g of raw ossa draconis, 20-30 g of raw oyster, 10-15 g of citrus chirocarpus, 5-10 g of rhizoma nardostachyos. The medicine of the invention has the efficacy of nourishing kidney and securing essence, nourishing yin and suppressing excessive yang, nourishing blood and calming nerves, has good effect for treating insomnia, has a high cure rate, and has the advantages of simple formula components, convenient processing and application, short treatment course, fast effect, and no recurrence.
Description
Technical field
The present invention relates to a kind of Chinese medicine medicine of Cure for insomnia, belong to traditional Chinese medical science field.
Background technology
Insomnia is clinical modal sleep disorder disease, and along with reform and opening-up and development of market economy, social competition strengthens day by day, and the pressure of people's work, studying and living constantly increases, and the insomniac of Yin Faing also increases gradually therefrom.It mainly shows as the lighter's difficulty falling asleep, easily wakes up in the sleep, and is difficult to fall asleep again, and wake up early morning too early.Weight person lies awake all night, and often with headache and dizzy, spiritlessness and weakness, palpitation and amnesia, irritability, dreaminess etc., the patient often experiences anxiety to insomnia and be frightened.Insomnia can cause that people's feeling of fatigue, general malaise, listless, delay of response, headache, attention can not concentrate, its maximum effect is spiritual aspect, seriously a bit can cause functional disease and each systemic diseases such as schizophrenia and depression, anxiety neurosis, autonomic nervous dysfunction, as cardiovascular system, digestive system etc., bring long-term misery to the patient.
At present, the usual method that the insomniac is alleviated this disease is to take the Western medicine sleeping pill, but can not treat at all, takes the dependence that can form sleeping pill for a long time, again because this class medicine all has certain side effect, take for a long time and also may cause than the even more serious disease of insomnia.Therefore, the insomnia has caused people's extensive concern, and becomes a big problem for the treatment of.The medicine of development of new has become a kind of exigence to reduce the side effect of sleeping pill in the past.
Summary of the invention
The purpose of this invention is to provide a kind of effect significantly, have no side effect, medication is convenient, the Chinese medicine decoction of Cure for insomnia with low cost, for realizing above purpose, the technical solution used in the present invention is:
This Chinese medicine decoction is made by the crude drug in the following weight scope: Radix Rehmanniae Preparata 3050g, Herba Epimedii 10-20g, Rhizoma Polygonati 20-30g, Fructus Ligustri Lucidi 10-20g, Fructus Schisandrae Chinensis 5-10g, Radix Paeoniae Alba 20-30g, Semen Ziziphi Spinosae 20-30g, Os Draconis 20-30g, Concha Ostreae 20-30g, Fructus Citri Sarcodactylis 10-20g, Radix Et Rhizoma Nardostachyos 5-10g.
The optimum weight of each crude drug is: Radix Rehmanniae Preparata 40g, Herba Epimedii 15g, Rhizoma Polygonati 25g, Fructus Ligustri Lucidi 15g, Fructus Schisandrae Chinensis 7g, Radix Paeoniae Alba 25g, Semen Ziziphi Spinosae 25g, Os Draconis 25g, Concha Ostreae 25g, Fructus Citri Sarcodactylis 15g, Radix Et Rhizoma Nardostachyos 7g.
Each crude drug pharmacological action is as follows:
Radix Rehmanniae Preparata: nature and flavor are sweet, and tepor is gone into liver, kidney channel, effect: nourishing YIN and supplementing blood, and beneficial essence is filled out marrow, is used for the hepatic and renal YIN deficiency, soreness of the waist and knees, hectic fever due to YIN-deficiency, hectic fever, the night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.
Herba Epimedii: nature and flavor suffering, sweet, temperature is gone into liver, kidney channel.Effect: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling is used for impotence and seminal emission, and the muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Rhizoma Polygonati: nature and flavor are sweet, and are flat, go into spleen, lung, kidney channel, effect: boosting qi and nourishing yin, and spleen invigorating, lung moistening, kidney tonifying is used for weakness of the spleen and stomach, fatigue and asthenia, the xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Fructus Ligustri Lucidi: nature and flavor are sweet, bitter, and are cool in nature, effect: the tonifying liver kidney yin, crow must make eye bright, and cures mainly: Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision.
Fructus Schisandrae Chinensis: nature and flavor acid, sweet, temperature, go into lung, the heart, kidney channel, effect: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming is used for the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
The Radix Paeoniae Alba: the nature and flavor picric acid, cold is gone into liver, spleen channel, effect: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, astringing YIN to stop sweating, the treatment breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Semen Ziziphi Spinosae: nature and flavor acid, flat, go into the heart, spleen, liver, gallbladder meridian, effect: nourishing the liver, mind calming is calmed the nerves, and arresting sweating is controlled restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.
Os Draconis: property sweet-puckery flavor, flat, go into the heart, liver, kidney, large intestine channel, effect: tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing, it is demented to control palpitation with fear, and palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, the seminal emission stranguria with turbid discharge is told nosebleed and is had blood in stool, bleeding not during menses, and the dysentery proctoptosis, ulcer does not close up for a long time.
Concha Ostreae: nature and flavor are salty, be slightly cold, and go into liver, gallbladder, kidney channel, effect: tranquillization with heavy prescription, and the YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweatingly, is used for the palpitation with fear insomnia, vertigo and tinnitus, scrofula sucutaneous nodule, note of the ancient Chinese abdominal mass mass in the abdomen, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache pantothenic acid.The Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.Be used for spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Fructus Citri Sarcodactylis: nature and flavor suffering, hardship, acid, temperature, go into liver, spleen, lung meridian, effect: liver-smoothing, qi-regulating, and stomach and alleviating pain are used for stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite vomiting.
Radix Et Rhizoma Nardostachyos: nature and flavor suffering, sweet, warm, go into spleen, stomach warp, effect: promoting the circulation of QI to relieve pain, relieving stagnation and activating the spleen.External damp eliminating detumescence.Be used for burnt QI stagnated by cold, incoordination between the spleen and stomach, inappetence, vomiting; Toothache is controlled in external.
Modern pharmacological research shows: Radix Rehmanniae Preparata, Herba Epimedii, Rhizoma Polygonati, Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Os Draconis, Concha Ostreae, the Radix Paeoniae Alba, Fructus Citri Sarcodactylis, Radix Et Rhizoma Nardostachyos etc. have the calming soporific function, and the effect of energy enhancing human body immunity function and endocrine regulation, therefore this Chinese medicine decoction compatibility is reasonable, have no side effect, effect easy to process, with low cost, as to have supplementing the kidney to control the nocturnal, nourishing YIN for attracting YANG, nourish blood and allay excitement, the energy Yin Yang balancing, mind tranquilizing.Make insomniac's mind clear, spirit is happy, makes cerebral cortex and nervous system reach balance of nature, is used for the treatment of insomnia, good effect, cure rate height.
The specific embodiment
The present invention will be further described below in conjunction with embodiment.
Following each raw material of Chinese medicine of at first weighing: Radix Rehmanniae Preparata 40g, Herba Epimedii 15g, Rhizoma Polygonati 25g, Fructus Ligustri Lucidi 15g, Fructus Schisandrae Chinensis 7g, Radix Paeoniae Alba 25g, Semen Ziziphi Spinosae 25g, Os Draconis 25g, Concha Ostreae 25g, Fructus Citri Sarcodactylis 15g, Radix Et Rhizoma Nardostachyos 7g; Then Concha Ostreae, Os Draconis, Concha Ostreae are mixed in the marmite, it is saturating to add blister, and other crude drug are inserted in another container, soak; Be decocted first Os Draconis, Concha Ostreae after half an hour, pour other crude drug into, first intense fire is fried boiling, and with half an hour at a simmer, leaches medicinal liquid again, adds water in the medicinal residues and fries in shallow oil half an hour, leaches medicinal liquid again, and two liquid of boiling medicine mix.
Using method: every day potion, each 1 decoction being taken warmly sooner or later, 30 days is a course for the treatment of.
The kidney tonifying of producing according to crude drug Radix Rehmanniae Preparata 40g of the present invention, Herba Epimedii 15g, Rhizoma Polygonati 30g, Fructus Ligustri Lucidi 15g, Fructus Schisandrae Chinensis 7g, Radix Paeoniae Alba 25g, Semen Ziziphi Spinosae 25g, Os Draconis 25g, Concha Ostreae 25g, Fructus Citri Sarcodactylis 15g, Radix Et Rhizoma Nardostachyos 7g is pacified soup Cure for insomnia disease 48 examples of sleeping below, and compare observation with the Western medicine diazepam tablets, the result reports as follows:
1, data and method
1.1 case is selected the diagnostic criteria in insomnia's reference " Chinese mental disorder classification and diagnostic criteria " (CCMD3), namely (1) almost is unique symptom with insomnia, comprise have difficulty in going to sleep, insomnia-middle, dreaminess, early awakening or the back of waking up are difficult for sleeping again, wake up back sense of discomfort, tired, or daytime is sleepy etc.; (2) insomnia takes place 3 times at least weekly, and one month at least; (3) insomnia causes significant worries, or the ergasia decrease in efficiency, or hinders social function; (4) no physical disease or mental disorder; (5) go down, regulate the unbalance aforementioned symptom that occurs because of function.
1.2 physical data 78 routine patients are my outpatient of institute, are divided into treatment group and matched group at random.48 examples are organized in treatment, male 30 examples wherein, women 18 examples.The oldest 64 years old, minimum 22 years old, 50 years old mean age; Person's 34 examples of often taking the sleeping pill, the course of disease is the longest 6 years, and is the shortest 4 months, average 1.9 years; Matched group 30 examples, male 19 examples wherein, women 11 examples, in maximum 66 years old of age at noon, minimum 21 years old, average 49 years old, the course of disease was the longest 6 years, and was the shortest 5 months. and average 1.8 years, through informal dress sleeping pill person 21 examples.Two groups of patients are aspect the situation of age, course of disease kimonos sleeping pill, and the equal not statistically significant of its difference (P＞0.05) points out two groups of patients to have comparability.
1.3 giving from intending kidney tonifying, Therapeutic Method treatment group pacifies the soup treatment of sleeping.Every day potion, decocting extracting juice 400ml is each 1 decoction being taken warmly sooner or later.1 month was 1 course for the treatment of.Carry out the curative effect statistics after finishing for 1 week the course for the treatment of.Matched group gives the Western medicine diazepam tablets, 5mg/ time, sleep every night preceding 30 minutes oral.1 month was 1 course for the treatment of.Carry out the curative effect statistics after finishing for 1 week the course for the treatment of.
1.4 criterion of therapeutical effect is drafted with reference to the criterion of therapeutical effect of insomnia in " new Chinese medicine clinical research guideline ".Clinical cure: recover the length of one's sleep normal or nighttime sleep time＞6 hour, sleep is dull, and the back of waking up is energetic.Produce effects: sleep is clearly better, and increases by 3 hours the length of one's sleep, and Depth of sleep increases, but total sleep time＜6 hour.Effectively: sx, the more preceding increase less than of sleeping 3 hours.Invalid: sleep nothing in treatment back is obviously improved or is increased the weight of.
1.5 Pittsburgh index (PSQI) evaluation.PSQI integration clauses and subclauses are simplified to 6 projects: sleep quality, time for falling asleep, the length of one's sleep, Sleep efficiency, sleeping pill are used, daytime function, every by score in 0～3 fen, accumulate to such an extent that be divided into PSQI total points (0～18 minute), score is more high, and the expression sleep quality is more poor.
1.6 the statistical method measurement data is with mean ± standard deviation
The t check is adopted in expression, and enumeration data adopts X 2 test.
2, result
2.1 two groups of patient's curative effects relatively see Table 1.Treatment group total effective rate 93.75%, matched group 76.67%, through X 2 test, P＜0.01, prompting treatment group effective percentage is higher than matched group.
Table 1 liang group curative effect is n (%) relatively
Annotate: compare * P＜0.01 with matched group
2.2 PSQI total mark improvement situation relatively sees Table 2 before and after two groups of patient treatments.Two groups of patient PSQI total mark treatment backs all obviously reduce before treating, and comparing difference has statistical significance (P＜0.01); Compare two groups for the treatment of backs, and the treatment group is improved more remarkable (P＜0.01); The difference of two groups for the treatment of back PSQI total marks compares, and difference also has statistical significance (P＜0.01).
PSQI total mark improvement situation relatively before and after the table 2 liang group patient treatment
Annotate: compare * P＜0.01 in organizing with before the treatment; Compare △ P＜0.01 with matched group
Results of comparison shows: the kidney tonifying peace of producing according to the present invention is slept, and to control the insomnia effect remarkable for soup, two groups of total effective rates relatively, difference has significance meaning (P＜0.01).PSQI total mark improvement situation compares before and after treatment group and the treatment of control group, and difference has significance meaning (P＜0.01); Particularly treatment back treatment group improve patient's time for falling asleep, aspects such as the sense of sleeping soundly, the subjective symptoms of waking up afterwards obviously are better than matched group, and do not have the common side effect of diazepam tablets such as drowsiness, asthenia, drug dependence.Show and sleep kidney tonifying peace men outnumbered women in the soup treatment that negative and positive are lost insomnia's determined curative effect of friendships, and can significantly improve insomniac's cardinal symptom, the raising sleep quality.
Claims (2)
1. the Chinese medicine decoction of a Cure for insomnia is characterized in that being made by the crude drug in the following weight scope: Radix Rehmanniae Preparata 30-50g, Herba Epimedii 10-20g, Rhizoma Polygonati 20-30g, Fructus Ligustri Lucidi 10-20g, Fructus Schisandrae Chinensis 5-10g, Radix Paeoniae Alba 20-30g, Semen Ziziphi Spinosae 20-30g, Os Draconis 20-30g, Concha Ostreae 20-30g, Fructus Citri Sarcodactylis 10-20g, Radix Et Rhizoma Nardostachyos 5-10g.
2. the Chinese medicine decoction of a kind of Cure for insomnia according to claim 1 is characterized in that the optimum weight of each crude drug is: Radix Rehmanniae Preparata 40g, Herba Epimedii 15g, Rhizoma Polygonati 25g, Fructus Ligustri Lucidi 15g, Fructus Schisandrae Chinensis 7g, Radix Paeoniae Alba 25g, Semen Ziziphi Spinosae 25g, Os Draconis 25g, Concha Ostreae 25g, Fructus Citri Sarcodactylis 15g, Radix Et Rhizoma Nardostachyos 7g.
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| CN102784358B (en) * | 2012-08-01 | 2013-10-09 | 蒋典华 | Preparation method of traditional Chinese medicine for treating liver stagnation insomnia |
| CN102861207A (en) * | 2012-08-30 | 2013-01-09 | 徐东健 | Decoction medicine for treating heart-kidney imbalance-type anhypnia |
| CN103919986A (en) * | 2014-04-01 | 2014-07-16 | 杜秀兰 | Traditional Chinese medicine for treating insomnia |
| CN104041816A (en) * | 2014-06-20 | 2014-09-17 | 苏州法莫生物技术有限公司 | Health-care product for improving sleep |
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