CN103977202A - Pharmaceutical composition and pharmaceutical preparation and preparation method and application thereof - Google Patents

Pharmaceutical composition and pharmaceutical preparation and preparation method and application thereof Download PDF

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CN103977202A
CN103977202A CN201410214268.5A CN201410214268A CN103977202A CN 103977202 A CN103977202 A CN 103977202A CN 201410214268 A CN201410214268 A CN 201410214268A CN 103977202 A CN103977202 A CN 103977202A
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content
weight
pharmaceutical composition
radix
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张跃华
徐新
孙立辉
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Abstract

The invention discloses a pharmaceutical composition. The pharmaceutical composition is prepared from the following raw materials: deer oil, pangolin scales, cowherb seed, uniflower swisscentaury root, angelica, radices trichosanthis, red peony root, akebiaquinata, pericarpium citri reticulatae viride, rhizoma cyperi, prepared rehmannia root and ligusticum wallichii, wherein relative to 100 parts by weight of deer oil, the content of pangolin scales, cowherb seed, uniflower swisscentaury root, angelica, radices trichosanthis, akebiaquinata, pericarpium citri reticulatae viride, prepared rehmannia root and ligusticum wallichii is respectively 150-900 parts by weight, the content of the red peony root is 400-1000 parts by weight, and the content of the rhizoma cyperi is 100-300 parts by weight. By taking the pharmaceutical composition provided by the invention, breast milk can be secreted faster, better and in large amount, thereby effectively solving the problem of difficult breast milk secretion after parturition and providing reliable guarantee for breastfeeding.

Description

Pharmaceutical composition and pharmaceutical preparation and preparation method thereof and their application
Technical field
The present invention relates to a kind of pharmaceutical composition, the pharmaceutical preparation of being prepared by this pharmaceutical composition, a kind of preparation method of pill, and the application of described pharmaceutical composition, described pharmaceutical preparation and the pill prepared by described preparation method.
Background technology
Along with social progress, expanding economy, people improve day by day to healthy understanding, and the mankind are that baby is carried out to breast feeding to the healthy understanding most important.
Breast milk is the best food of baby, although it seems so thick unlike milk, it is suitable that it contains all nutrition and content that baby grows up required.Breast milk is very useful to baby's health.Breast-fed babies suffer from the probability of gastroenteritis and thoracic cavity infection lower than the baby of milk powder nursing.The several leading sky of just birth, colostrum can also be protected baby's intestinal, prevents gastrointestinal upset.Compare with milk, breast milk more easily absorbs, and the baby who drinks breast milk is not easy constipation.Because breast milk is almost absorbed completely, the feces that therefore baby discharges can be not too many.Breast feeding can also reduce the probability that baby suffers from diaper rash.And the area of feeding in some custom suckling, the sickness rate of breast carcinoma is very low.Its reason may be to feed the antibody producing and provide certain protection for parent due to suckling.
But after fetal birth, be often faced with the delay secretion of milk, or galactopoiesis deficiency often, make complete breast feeding be difficult to realize.
Summary of the invention
The object of the invention is the normal secretion in order to ensure breast milk, a kind of pharmaceutical composition that can effectively promote breast milk secretion is provided.
To achieve these goals, on the one hand, the invention provides a kind of pharmaceutical composition, wherein, this pharmaceutical composition is prepared from by following raw material: deer oil, Squama Manis, Semen Vaccariae, Radix Rhapontici, Radix Angelicae Sinensis, Radix Trichosanthis, Radix Paeoniae Rubra, Caulis Akebiae, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, wherein, with respect to the deer oil of 100 weight portions, the content of Squama Manis, Semen Vaccariae, Radix Rhapontici, Radix Angelicae Sinensis, Radix Trichosanthis, Caulis Akebiae, Pericarpium Citri Reticulatae Viride, Radix Rehmanniae Preparata and the Rhizoma Chuanxiong 150-900 weight portion of respectively doing for oneself, the content of Radix Paeoniae Rubra is 400-1000 weight portion, and the content of Rhizoma Cyperi is 100-300 weight portion.
On the other hand, the invention provides a kind of pharmaceutical preparation, this pharmaceutical preparation contains active component and pharmaceutically acceptable adjuvant, and wherein, described active component is pharmaceutical composition as above.
Again on the one hand, the invention provides a kind of preparation method of pill, the method comprises, by pharmaceutical composition as above, pharmaceutically acceptable adjuvant as above mixes and molding.
Meanwhile, the present invention also provides the pill of being prepared by method as above.
Another aspect, the present invention also provides pharmaceutical composition as above, pharmaceutical preparation as above, and pill as above is in lactogenic and prepare the application in Lactogenic medicine.
By taking pharmaceutical composition provided by the invention, can make the faster and better and a large amount of secretion of breast milk, after the product baby who effectively solves, breast milk is secreted a difficult difficult problem, for the nursing of breast milk provides reliable guarantee.
Other features and advantages of the present invention are described in detail the detailed description of the invention part subsequently.
Detailed description of the invention
Below the specific embodiment of the present invention is elaborated.Should be understood that, detailed description of the invention described herein only, for description and interpretation the present invention, is not limited to the present invention.
On the one hand, the invention provides a kind of pharmaceutical composition, wherein, this pharmaceutical composition is prepared from by following raw material: deer oil, Squama Manis, Semen Vaccariae, Radix Rhapontici, Radix Angelicae Sinensis, Radix Trichosanthis, Radix Paeoniae Rubra, Caulis Akebiae, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, wherein, with respect to the deer oil of 100 weight portions, the content of Squama Manis, Semen Vaccariae, Radix Rhapontici, Radix Angelicae Sinensis, Radix Trichosanthis, Caulis Akebiae, Pericarpium Citri Reticulatae Viride, Radix Rehmanniae Preparata and the Rhizoma Chuanxiong 150-900 weight portion of respectively doing for oneself, the content of Radix Paeoniae Rubra is 400-1000 weight portion, and the content of Rhizoma Cyperi is 100-300 weight portion.
Preferably, with respect to the deer oil of 100 weight portions, the content of Squama Manis is the content of 250-450 weight portion, Semen Vaccariae and Caulis Akebiae the 200-600 weight portion of respectively doing for oneself, the content of Radix Rehmanniae Preparata is 150-700 weight portion, the content of Rhizoma Chuanxiong is 300-550 weight portion, the content of Radix Rhapontici and the Pericarpium Citri Reticulatae Viride 150-600 weight portion of respectively doing for oneself, and the content of Radix Trichosanthis is 200-450 weight portion, the content of Radix Paeoniae Rubra is 400-900 weight portion, and the content of Rhizoma Cyperi is 150-200 weight portion.
Pharmaceutical composition of the present invention depends on above specific medicine and specific content is used in conjunction with, to bring into play the effect of effective lactogenic.Under preferred content range, its lactogenic effect is better.
According to the present invention, the state of the raw material for the preparation of described compositions is had no particular limits, for example, can be pulverulence, can be also the liquid condition boiling, those skilled in the art can select according to practical situation.Preferably, described raw material, except deer oil, is preferably pulverulence, and described powder is to pass through the siftage of 80-150 mesh sieve, more preferably can pass through the siftage of 100-120 mesh sieve.
Deer oil: being commonly called as deer lipoid, is the fatty oil of animal in deer family Cervus nippon Temminck or Cervus elaphus linnaeus, is yellow-white bulk, strip or lamellar, the glossy gloss of tool, translucent, body is light, softness, fatty oil canescence, like condensation fat sample, matter is hard, satiny.
Squama Manis is Manidae animal Manitis (having another name called Squama Manis) scale (Pangolin).The big gun process of processing is: first sand is put into pot heating, and then put into raw first sheet, be heated to the complete big gun of first sheet and rise, in pot, take out, sieved silt particle, cross while hot vinegar, pull out, dry, get final product to obtain Squama Manis.Wherein, catch after Squama Manis, strip a full scute skin and dry, be first and open, first is opened and put in boiling water, scale self falling, dries, and is first sheet.
Semen Vaccariae: the dry mature seed of pinkwort Vaccaria segetalis (Vaccariasegetalis (Neck) Garcke).Tap plant when fruit maturation, peel not yet ftracture summer, dries, and lays seed, removes impurity, then dry.
This product is spherical in shape, surface black, and minority rufous, slightly glossy, there is fine and closely woven graininess projection, a side has the longitudinal furrow of 1 depression.Matter is hard.Endosperm white, the bending ring formation of embryo.Feeble QI, taste is micro-puckery, bitter.
Radix Rhapontici is the root of feverfew centaurea monanthos Georgi (Rhaponticum uni-florum (L.) DC.) or Radix Echinopsis (Echinps latifolius Tausch.).Clean impurity is excavated, chosen to spring and autumn, and unhairing is cleaned, and runs through, and rear acquisition is dried in section.
Radix Angelicae Sinensis (ANGELICAESINENSISRADIX) is the dry root of umbelliferae angelica (Angelica sinensis (Oliv.) Diels).
Radix Angelicae Sinensis is slightly cylindrical, and supporting root is arranged at bottom.Surface yellowish-brown is to sepia, and tool is indulged wrinkle and the hole skin sample projection of growing crosswise.Root head (returning head) tool ring grain, upper end circle is blunt, or the several obviously outstanding rhizome traces of tool, has the residue of purple or yellowish green stem and sheath; Main root (returning body) surface irregularity; Supporting root (Radix Angelicae Sinensis) is upper coarse and lower fine, and many distortions have minority mark of fibrous root.Matter is pliable and tough, section yellow-white or fallow, and skin zone is thick, has crack and most brown point-like secretory cavity, and woody part color is lighter, cambium ring yellowish-brown.There is strong fragrance, sweet in the mouth, pungent, micro-hardship.Chai Xing great, withered be green and brown color person without oil or section can not hyoscine.By raw material is removed to impurity, clean, run through, shave, dries or cold drying obtains.
Radix Trichosanthis: the dry root of cucurbitaceous plant Fructus Trichosanthis (Trichosanthes kirilowii Maxim.) or trichosanthes rosthornii Harms (Trichosanthes rosthornii HarIlls).Autumn, two seasons of winter excavate, and clean, and remove crust, and cutting or vertical profile become lobe, dry rear acquisition.
This product is irregular roundness cylindricality, spindle or lobe bulk.Surface yellow-white or light brown yellow, the hole skin of growing crosswise that has vertical wrinkle, radicula trace and slightly cave in, what have has yellowish-brown crust residual.Matter is solid, section white or faint yellow, and rich mealiness, cross section visible yellow color xylem, is slightly radial arrangement, longitudinal section visible yellow color striated xylem.Feeble QI, mildly bitter flavor.
Radix Paeoniae Rubra: the dry root of ranunculaceae plant Radix Paeoniae (Paeonia lactiflora Pall.) or river Radix Paeoniae Rubra (Paeonia veitchii Lynch).Spring, Qiu Erji excavate, and remove rhizome, fibrous root and silt, dry rear acquisition.
This product is cylindrical, slightly bending.Surface sepia, coarse, there are longitudinal furrow and wrinkle, and the hole skin sample projection that has mark of fibrous root and grow crosswise, some crusts easily come off.Matter is hard and crisp, frangibility, and section white powder or pink, skin zone is narrow, and the radial texture of woody part is obvious, and what have has a crack.Feeble QI perfume (or spice), mildly bitter flavor, sour and astringent.
Caulis Akebiae: plants of Lardizabalaceae Caulis Akebiae (Akebiaquinata (Thunb.) Decne.), leaf Caulis Akebiae (Akebiafrzfoliata (Thunb.) Koidz.) or Caulis Akebiae (Akebiatrifoliata (Thunb.) Koidz.var.australis ([Diels) Rehd.] dry rattan.Gather autumn, intercepts stem, removes withe, dries in the shade.
This product is cylindrical, often slightly distortion.Surface taupe brown is to taupe, and crust is coarse and have many irregular splittings or a longitudinal furrow stricture of vagina, bossed hole skin.Joint portion expands or is not obvious, tool side shoot mark of break.Body is light, and matter is solid, not frangibility, and section is irregular, and skin zone is thicker, yellowish-brown, visible faint yellow graininess point, woody part yellow-white, ray is radial arrangement, marrow little or hollow, yellow-white or yellowish-brown sometimes.Feeble QI, mildly bitter flavor and puckery.
Pericarpium Citri Reticulatae Viride: rutaceae orange (Citrus reticulata Blanco) and the dry young fruit of variety or the peel of immature fruit.Collect the 5-6 month from the young fruit falling, dry, practise and claim " FTUCTUS CITRI IMMATURI "; The green fruit of gathering the 7-8 month, on peel, vertical profile becomes pintongs to base portion, eliminates flesh lobe, dries, and practises and claims " Sihuaqingpi ".
Sihuaqingpi peel cuts open into 4 slivers, sliver oblong.Outer surface celadon or blackish green, the most grease chambeies of close life; Inner surface off-white color or yellow-white, coarse, the little grain of attached yellow-white or yellowish-brown.Matter is slightly hard, frangibility, and section outer rim has the 1-2 of grease chamber row.Gas perfume (or spice), bitter in the mouth, pungent.It is spherical that FTUCTUS CITRI IMMATURI is class.Surface celadon or blackish green, micro-coarse, there is fine and closely woven recessed grease chamber, there is the slightly base for post of projection on top, and base portion has net form carpopodium trace.Matter is hard, section peel yellow-white or fallow, light brown.Gas delicate fragrance, sour in the mouth, hardship, pungent.
Rhizoma Cyperi: be the dry rhizome of sedge dried tuber (Cyperus rotundus L.).Excavate autumn, sing the hair must, put in boiling water, slightly boil or steam after dry, or burn and directly dry afterwards.
This product is spindle more, some summary bendings.Surface sepia or pitchy, have vertical wrinkle, and have the slightly link of protuberance, has brown feeler and the fibrous root mark of break of not Ex-all on joint; Person is more smooth to remove feeler, and link is not obvious.Matter is hard, through steaming and decocting person's section yellowish-brown or rufous, and cutin sample; Sun-dried person is broken pale complexion and is shown mealiness, and endodermis ring grain is obvious, and center pillar color is darker, and point-like vascular bundle is dispersed in.Gas perfume (or spice), mildly bitter flavor.
Radix Rehmanniae Preparata (REHMANNIA ERADIX PRAEPARATA): the Preparation process product of Radix Rehmanniae, get Radix Rehmanniae, stew to wine exhaustion according to stewed with wine method, take out, when dry in the sun is slightly dry to crust mucus, cut sheet or piece, dry, to obtain final product.Every 100kg Radix Rehmanniae, uses yellow wine 30-50kg.Or, get Radix Rehmanniae,, take out to black profit according to the steaming of steaming method, when solarization is dry to approximately eighty per cant, cut sheet or piece, dry, to obtain final product.
This product is irregular sheet, fragment, and size, thickness differ.Surface corvinus, glossy, stickiness is large.Soft and the band toughness of matter, not frangibility, section corvinus, glossy.Feeble QI, taste is sweet.
Rhizoma Chuanxiong; The dry rhizome of samphire Rhizoma Chuanxiong (Ligusticum chuanxiong Hort.).Summer is significantly outstanding when joint dish on stem, and slightly excavates when purple.Remove silt, shine post-drying, then remove fibrous root.
This product is irregular nodular pattern fist shape agglomerate.Surface yellowish-brown, coarse shrinkage, has the wheel of most parallel ridges to save, and there is the similar round stem trace of depression on top, on downside and wheel joint, has most tubercle shape root traces.Matter is solid, not frangibility, and section yellow-white or lark, the loose grease chamber that has yellowish-brown, it is wavy that cambium ring is.Gas giving off a strong fragrance, bitter in the mouth, pungent, slightly numb feeling in the tongue, micro-Hui Tian.
Source to above-mentioned various raw materials in the present invention has no particular limits, and for example, can on market, buy the product having cooked, and also can obtain by conventional concocting method, for example, can make by raw material is dried and is ground.Dry method can, for drying or naturally drying, be preferably nature and dry.The method of grinding can be the Ginding process of field of Chinese medicines routine, and the condition optimization of grinding makes described raw material can pass through the powder of 80-150 object sieve aperture, preferably can pass through 100-120 object sieve aperture.
According to the present invention, there is no particular limitation to prepare the method for described pharmaceutical composition by above raw material, can be prepared according to the method for this area routine, do not repeat them here.
Second aspect, the present invention also provides a kind of pharmaceutical preparation, and this pharmaceutical preparation contains active component and pharmaceutically acceptable adjuvant, and wherein, described active component is pharmaceutical composition as above.
According to the present invention, described active component and pharmaceutically acceptable adjuvant can be prepared into any type of pharmaceutical preparation.For example, can be unguentum, capsule or pill.Described pharmaceutically acceptable adjuvant can specifically be selected according to the dosage form of prepared pharmaceutical preparation, described selection according to being conventionally known to one of skill in the art, do not repeat them here.
According to the present invention, more than the purity of described active component is preferably 98 % by weight, more preferably more than 99 % by weight.
The present inventor's discovery, in the time that described pharmaceutical preparation is pill, by oral administration, curative effect is better.Taking the gross weight of pharmaceutical preparation as benchmark, the content of described active component can be 30-60 % by weight, is preferably 40-50 % by weight, and the content of described adjuvant is 40-70 % by weight, is preferably 50-60 % by weight.
Described pill is preferably honeyed pill, and described Optimization of Adjuvant is Mel, and described Mel can be commercially available various Mel.
Based on this, the present invention also provides a kind of preparation method of pill, and the method comprises, drug regimen provided by the invention is mixed with adjuvant as above and molding.
Pharmaceutical composition of the present invention can be by mixing described various raw materials to make.Taking the gross weight of the pill that makes as benchmark, the consumption of described active component can be 30-60 % by weight, is preferably 40-50 % by weight, and the consumption of described adjuvant is 40-70 % by weight, is preferably 50-60 % by weight.
Described Optimization of Adjuvant is Mel.The temperature of described mixing can be 60-95 DEG C, is preferably 70-90 DEG C, and the time of mixing can be 10-60 minute.
The method of described molding can adopt the conventional forming method for the preparation of pill, for example, the medicine piece that mixes shape type can be put into pellet processing machine and become ball.Preferably make the small honey pill of about 0.6-10 gram with doctor's pellet processing machine.
The present invention also provides a kind of pharmaceutical composition as above, pharmaceutical preparation as above, and the pharmaceutical preparation of being prepared by method as above is in lactogenic and prepare the application in Lactogenic medicine.
The pharmaceutical composition being formed by the raw material of content described above, pharmaceutical preparation as above, and the pill that as described above prepared by method can have no side effect and play the effect of lactogenic, breast milk secreted to difficult puerpera and have good curative effect.
Below will describe the present invention by embodiment.After respectively Squama Manis, Semen Vaccariae, Radix Rhapontici, Radix Angelicae Sinensis, Radix Trichosanthis, Radix Paeoniae Rubra, Caulis Akebiae, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi, Radix Rehmanniae Preparata and Rhizoma Chuanxiong being dried, grind, and screen with 120 object screen clothes, and select the siftage of each raw material for the preparation of pharmaceutical composition of the present invention.
Table 1
Embodiment Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5
Pharmaceutical composition numbering A1 A2 A3 A4 A5
Deer oil 100 100 100 100 100
Squama Manis 300 450 255 150 900
Semen Vaccariae 300 200 600 900 150
Radix Rhapontici 350 150 600 180 850
Radix Angelicae Sinensis 900 150 335 800 120
Radix Trichosanthis 450 450 200 860 100
Radix Paeoniae Rubra 900 400 565 400 1000
Caulis Akebiae 600 400 200 145 870
Pericarpium Citri Reticulatae Viride 550 150 600 160 890
Rhizoma Cyperi 200 150 165 100 300
Radix Rehmanniae Preparata 700 150 600 850 150
Rhizoma Chuanxiong 300 450 535 140 850
Embodiment 1-5
Embodiment 1-5 is for the preparation of the pharmaceutical composition that the invention provides thing.
According to the consumption shown in table 1 (all in weight portion), each raw material is mixed, make respectively compositions A1-A5.
Comparative example 1
This comparative example is for the preparation of pharmaceutical composition provided by the invention.
According to the method pharmaceutical compositions of embodiment 1, different, in described pharmaceutical composition, do not contain deer oil and Squama Manis.Make compositions D1.
Embodiment 6-10
Embodiment 6-10 is for the preparation of pill provided by the invention.
According to the formula in table 2, Mel is heated to 80 DEG C, the Chinese medicine composition A1-A5 then respectively being prepared by embodiment 1-5 joins in Mel, endures 20 minutes at 80 DEG C.Then after being naturally cooled to 25 DEG C, joining in pellet processing machine and make ball, the weight of every ball is 0.6 gram, obtains pill B1-B5.Obtain wrapping with charta after pill, put into plastics pill container, what externalization was good seals with wax solid, packs in packing box for subsequent use.
Table 2
Embodiment numbering Embodiment 6 Embodiment 7 Embodiment 8 Embodiment 9 Embodiment 10
Pill B1 B2 B3 B4 B5
Pharmaceutical composition (% by weight) A1(45) A2(40) A3(50) A4(30) A5(60)
Mel (% by weight) 55 60 50 70 40
Comparative example 2
Comparative example 2 is for the preparation of the pill of reference.
Method according to embodiment 6 is prepared pill, different, and the pharmaceutical composition using is D1, obtains pill E1.
Test case 1
Test case 1 for pill that above preparation is described to psoriatic therapeutic effect.
Select 48 puerperas with galactopoiesis difficulty, be divided at random 6 groups, every group of 8 people.Wherein, experimental group 1-5 takes respectively pill B1-B5, and matched group is taken pill E1.
Experimental group 1-5 and matched group, each serving with corresponding pill 10 balls, are respectively taken 1 time sooner or later, under warm water clothes.Within 7 days, be a course for the treatment of, after 6 courses for the treatment of, record curative effect.Wherein, be as the criterion with the enough consumption by infants of breast milk secretory volume, be designated as effective treatment.
After 6 courses for the treatment of, the treated effect of experimental group is respectively 87.6%, 100%, 100%, 87.5% and 100%, and effective treatment rate of matched group is 50%.
As can be seen from the above results, pharmaceutical composition provided by the invention and pharmaceutical preparation can promote galactopoiesis more effectively, and its curative effect depends on the specific proportioning of each composition.
More than describe the preferred embodiment of the present invention in detail; but the present invention is not limited to the detail in above-mentioned embodiment, within the scope of technical conceive of the present invention; can carry out multiple simple variant to technical scheme of the present invention, these simple variant all belong to protection scope of the present invention
It should be noted that in addition each the concrete technical characterictic described in above-mentioned detailed description of the invention, in reconcilable situation, can combine by any suitable mode.For fear of unnecessary repetition, the present invention is to the explanation no longer separately of various possible compound modes.
In addition, also can carry out combination in any between various embodiment of the present invention, as long as it is without prejudice to thought of the present invention, it should be considered as content disclosed in this invention equally.

Claims (10)

1. a pharmaceutical composition, it is characterized in that, this pharmaceutical composition is prepared from by following raw material: deer oil, Squama Manis, Semen Vaccariae, Radix Rhapontici, Radix Angelicae Sinensis, Radix Trichosanthis, Radix Paeoniae Rubra, Caulis Akebiae, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, wherein, with respect to the deer oil of 100 weight portions, the content of Squama Manis, Semen Vaccariae, Radix Rhapontici, Radix Angelicae Sinensis, Radix Trichosanthis, Caulis Akebiae, Pericarpium Citri Reticulatae Viride, Radix Rehmanniae Preparata and the Rhizoma Chuanxiong 150-900 weight portion of respectively doing for oneself, the content of Radix Paeoniae Rubra is 400-1000 weight portion, and the content of Rhizoma Cyperi is 100-300 weight portion.
2. pharmaceutical composition according to claim 1, wherein, with respect to the deer oil of 100 weight portions, the content of Squama Manis is the content of 250-450 weight portion, Semen Vaccariae and Caulis Akebiae the 200-600 weight portion of respectively doing for oneself, and the content of Radix Rehmanniae Preparata is 150-700 weight portion, and the content of Rhizoma Chuanxiong is 300-550 weight portion, the content of Radix Rhapontici and the Pericarpium Citri Reticulatae Viride 150-600 weight portion of respectively doing for oneself, the content of Radix Trichosanthis is 200-450 weight portion, and the content of Radix Paeoniae Rubra is 400-900 weight portion, and the content of Rhizoma Cyperi is 150-200 weight portion.
3. pharmaceutical composition according to claim 1 and 2, wherein, described pharmaceutical composition is can be by the powder of the sieve aperture of 80-150 mesh sieve.
4. a pharmaceutical preparation, this pharmaceutical preparation contains active component and pharmaceutically acceptable adjuvant, it is characterized in that, and described active component is the pharmaceutical composition described in any one in claim 1-3.
5. pharmaceutical preparation according to claim 4, wherein, taking the gross weight of described pharmaceutical preparation as benchmark, the content of described active component is 30-60 % by weight, the content of described adjuvant is 40-70 % by weight.
6. pharmaceutical preparation according to claim 5, wherein, taking the gross weight of described pharmaceutical preparation as benchmark, the content of described active component is 40-50 % by weight, the content of described adjuvant is 50-60 % by weight.
7. according to the pharmaceutical preparation described in any one in claim 4-6, wherein, described adjuvant is Mel.
8. a preparation method for pill, the method comprises, by the pharmaceutical composition described in any one in claim 1-3, the pharmaceutically acceptable adjuvant in claim 4-7 described in any one mixes and molding.
9. the pill that prepared by method claimed in claim 8.
10. the pharmaceutical composition described in any one in claim 1-3, the pharmaceutical preparation in claim 4-7 described in any one, and pill claimed in claim 9 is in lactogenic and prepare the application in Lactogenic medicine.
CN201410214268.5A 2014-05-20 2014-05-20 Pharmaceutical composition and pharmaceutical preparation and preparation method and application thereof Pending CN103977202A (en)

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Publication number Priority date Publication date Assignee Title
CN102805388A (en) * 2011-05-31 2012-12-05 于春泓 Lactogenic health-protection nutritional soup
CN103610737A (en) * 2013-12-10 2014-03-05 通化华夏药业有限责任公司 Lactation-promoting medicine containing mongolian snakegourd root and pangolin

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Publication number Priority date Publication date Assignee Title
CN102805388A (en) * 2011-05-31 2012-12-05 于春泓 Lactogenic health-protection nutritional soup
CN103610737A (en) * 2013-12-10 2014-03-05 通化华夏药业有限责任公司 Lactation-promoting medicine containing mongolian snakegourd root and pangolin

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