CN103977165A - Traditional Chinese medicine preparation dedicated to anesthesia before operation and preparation method thereof - Google Patents
Traditional Chinese medicine preparation dedicated to anesthesia before operation and preparation method thereof Download PDFInfo
- Publication number
- CN103977165A CN103977165A CN201410240604.3A CN201410240604A CN103977165A CN 103977165 A CN103977165 A CN 103977165A CN 201410240604 A CN201410240604 A CN 201410240604A CN 103977165 A CN103977165 A CN 103977165A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- chinese medicine
- medicine preparation
- portions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 72
- 238000002360 preparation method Methods 0.000 title claims abstract description 62
- 206010002091 Anaesthesia Diseases 0.000 title claims abstract description 23
- 230000037005 anaesthesia Effects 0.000 title claims abstract description 23
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 235000011201 Ginkgo Nutrition 0.000 claims abstract description 9
- 235000008100 Ginkgo biloba Nutrition 0.000 claims abstract description 9
- 244000194101 Ginkgo biloba Species 0.000 claims abstract 2
- 210000000582 semen Anatomy 0.000 claims description 16
- 239000004615 ingredient Substances 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 9
- 239000012153 distilled water Substances 0.000 claims description 9
- 239000000284 extract Substances 0.000 claims description 9
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 241000345811 Neocheiropteris ovata Species 0.000 claims description 8
- 239000000706 filtrate Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 4
- -1 boil 2~3 hours Substances 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 238000005202 decontamination Methods 0.000 claims description 3
- 230000003588 decontaminative effect Effects 0.000 claims description 3
- 238000007598 dipping method Methods 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 239000012535 impurity Substances 0.000 claims description 3
- 239000004570 mortar (masonry) Substances 0.000 claims description 3
- 241000592346 Ginkgophyta Species 0.000 claims 4
- 244000184734 Pyrus japonica Species 0.000 claims 4
- 230000000694 effects Effects 0.000 abstract description 7
- 230000003444 anaesthetic effect Effects 0.000 abstract description 5
- 238000002695 general anesthesia Methods 0.000 abstract description 4
- 230000000703 anti-shock Effects 0.000 abstract description 3
- 238000002690 local anesthesia Methods 0.000 abstract description 3
- 241000427159 Achyranthes Species 0.000 abstract 1
- 241000202573 Dendropanax Species 0.000 abstract 1
- 244000304222 Melaleuca cajuputi Species 0.000 abstract 1
- 235000001167 Melaleuca cajuputi Nutrition 0.000 abstract 1
- 235000017710 Melaleuca viridiflora Nutrition 0.000 abstract 1
- 240000000569 Musa basjoo Species 0.000 abstract 1
- 235000000139 Musa basjoo Nutrition 0.000 abstract 1
- 241000345784 Neolepisorus Species 0.000 abstract 1
- 241000218093 Phedimus aizoon Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 235000018167 Reynoutria japonica Nutrition 0.000 abstract 1
- 240000001341 Reynoutria japonica Species 0.000 abstract 1
- 241000734689 Salomonia Species 0.000 abstract 1
- 241000133134 Saussurea Species 0.000 abstract 1
- 240000006677 Vicia faba Species 0.000 abstract 1
- 235000010749 Vicia faba Nutrition 0.000 abstract 1
- 241001251949 Xanthium sibiricum Species 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 description 17
- 230000036407 pain Effects 0.000 description 15
- 230000001737 promoting effect Effects 0.000 description 10
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- 210000004185 liver Anatomy 0.000 description 8
- 235000009508 confectionery Nutrition 0.000 description 7
- 231100000614 poison Toxicity 0.000 description 7
- 208000004880 Polyuria Diseases 0.000 description 6
- 230000017531 blood circulation Effects 0.000 description 6
- 230000035619 diuresis Effects 0.000 description 6
- 208000014674 injury Diseases 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 230000002980 postoperative effect Effects 0.000 description 6
- 230000008736 traumatic injury Effects 0.000 description 6
- 210000002216 heart Anatomy 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 210000000952 spleen Anatomy 0.000 description 5
- 230000008961 swelling Effects 0.000 description 5
- 239000003440 toxic substance Substances 0.000 description 5
- 206010063409 Acarodermatitis Diseases 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 4
- 241000447727 Scabies Species 0.000 description 4
- 238000012790 confirmation Methods 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 230000023597 hemostasis Effects 0.000 description 4
- 241000411851 herbal medicine Species 0.000 description 4
- 208000005687 scabies Diseases 0.000 description 4
- 208000006820 Arthralgia Diseases 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 3
- 241000218628 Ginkgo Species 0.000 description 3
- 206010030113 Oedema Diseases 0.000 description 3
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 208000002894 beriberi Diseases 0.000 description 3
- 230000001914 calming effect Effects 0.000 description 3
- 208000001848 dysentery Diseases 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 230000001717 pathogenic effect Effects 0.000 description 3
- 201000003068 rheumatic fever Diseases 0.000 description 3
- 235000014347 soups Nutrition 0.000 description 3
- 210000003932 urinary bladder Anatomy 0.000 description 3
- 241001517488 Clavus Species 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 208000008454 Hyperhidrosis Diseases 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 206010024229 Leprosy Diseases 0.000 description 2
- 208000001431 Psychomotor Agitation Diseases 0.000 description 2
- 206010038743 Restlessness Diseases 0.000 description 2
- 206010040943 Skin Ulcer Diseases 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 208000033809 Suppuration Diseases 0.000 description 2
- 206010053615 Thermal burn Diseases 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 206010013990 dysuria Diseases 0.000 description 2
- 208000014617 hemorrhoid Diseases 0.000 description 2
- 230000037315 hyperhidrosis Effects 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 201000007227 lymph node tuberculosis Diseases 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000004084 narcotic analgesic agent Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- 229960004919 procaine Drugs 0.000 description 2
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 231100000019 skin ulcer Toxicity 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 210000002435 tendon Anatomy 0.000 description 2
- 208000004371 toothache Diseases 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 230000002936 tranquilizing effect Effects 0.000 description 2
- 239000002435 venom Substances 0.000 description 2
- 231100000611 venom Toxicity 0.000 description 2
- 210000001048 venom Anatomy 0.000 description 2
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 description 1
- HOMSOWZTBJWNHP-UHFFFAOYSA-N 5-chlorothiadiazole Chemical compound ClC1=CN=NS1 HOMSOWZTBJWNHP-UHFFFAOYSA-N 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000193738 Bacillus anthracis Species 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- 201000006390 Brachial Plexus Neuritis Diseases 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 241000186216 Corynebacterium Species 0.000 description 1
- 206010012434 Dermatitis allergic Diseases 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 208000007875 Femur Head Necrosis Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 241000202721 Guihaia Species 0.000 description 1
- 206010019345 Heat stroke Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 208000029951 Laryngeal disease Diseases 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- 208000019695 Migraine disease Diseases 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 206010050031 Muscle strain Diseases 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010029229 Neuralgic amyotrophy Diseases 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 206010051373 Wound haemorrhage Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 238000001949 anaesthesia Methods 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 229940035674 anesthetics Drugs 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 229960003150 bupivacaine Drugs 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 206010013023 diphtheria Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000027119 gastric acid secretion Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 208000001786 gonorrhea Diseases 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000007866 hepatic necrosis Effects 0.000 description 1
- 206010019692 hepatic necrosis Diseases 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229960004194 lidocaine Drugs 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 206010027599 migraine Diseases 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- VDYCLYGKCGVBHN-UHFFFAOYSA-N pachymaic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC(=C)C(C)C)C(O)=O)C(O)CC21C VDYCLYGKCGVBHN-UHFFFAOYSA-N 0.000 description 1
- SRDNLMOBFKJOSD-UHFFFAOYSA-N pachymic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C(O)=O)C(O)CC21C SRDNLMOBFKJOSD-UHFFFAOYSA-N 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 201000009890 sinusitis Diseases 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000002691 topical anesthesia Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine preparation dedicated to anesthesia before operation and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine preparation disclosed by the invention is prepared from the following raw materials: cajeput, honeycomb, Japanese saussurea herb, dentiferous dendropanax root and stem, poria cocos, folium artemisiae argyi, common achyranthes herb, sedum aizoon, leaf of japanese banana, xanthium sibiricum, tuber fleeceflower stem, vicia faba, canton salomonia herb, radix angelicae pubescentis, ginkgo seed and ovate neolepisorus herb. According to the traditional Chinese medicine preparation, high-grade traditional Chinese medicinal materials are selected so as to be combined, so that the traditional Chinese medicine preparation accords with the theories of the traditional Chinese medicine and pharmacy and the modern medicine and pharmacology, is applicable to local anesthesia and general anesthesia, has an antishock effect, is convenient to use, safe and reliable, has a significant anesthetic effect in clinical practice, can be applied to anesthetization of various clinical operations, and is worthy of extensive popularization and application in clinic.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation and preparation method that is exclusively used in preoperative anesthesia.
Background technology
According to relevant anaesthesia technology, describe, world's literature record is the earliest the Han dynasty that appears at China, by the fiber crops of the famous surgical specialist of ancient Chinese, the Chinese medicine scholar Huatuo doctor invention soup that boils, the fiber crops soup that boils is that Chinese medicine decoction is equivalent to present oral general anesthesia agent, and operation is lost and is convenient to implement in oral rear patient's loss of consciousness dermal sensation.The fiber crops soup that boils belongs to the drug anesthesia technology that the world was leading at that time.But because of the remote past and year-by-year wars are flowed in lost.Doctor trained in Western medicine had been invented various anesthetis afterwards, as lignocaine now prevailing, bupivacaine, procaine etc.As the topical anesthesia that will implement local skin just must enter by drug injection that Intradermal just can play anesthesia with syringe and the anesthetics of oral Chinese medicine preparation has not yet to see so far open report and enters pharmacopeia in clinical application.
At present, in China market, there is multiple anesthesia product, be mostly Western medicine product, and price is higher, excessive for the side effect of patient with operation, even cause certain operation dangerous.China's Chinese medicine has very long history aspect anesthesia, if therefrom reappear a kind of anesthetis of Chinese medicine preparation in pharmacopeia nationality, solves the problem that existing anesthesia art exists, and for anesthesia research field, will have important Research Significance.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method that is exclusively used in preoperative anesthesia; The selected high-quality Chinese crude drug of Chinese medicine preparation of the present invention compatibility, meet Chinese medicine and pharmacy and modern medicine theory, be applicable to local anesthesia and general anesthesia, there is antishock effect, easy to use, safe and reliable, in clinical practice, there is very significant anaesthetic effect, can apply the narcotic analgesic with various clinical operations, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be exclusively used in a Chinese medicine preparation for preoperative anesthesia, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Be exclusively used in a preparation method for the Chinese medicine preparation of preoperative anesthesia, comprise following processing step:
(1) Cortex Melaleucae leucadendrae, Poria, Folium Artemisiae Argyi, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba sedi kamtschatici, Herba Xanthii, Caulis Polygoni Multiflori, Herba Salomoniae Cantoniensis and Radix Angelicae Pubescentis are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) by Nidus Vespae and Semen Viciae fabae decontamination, after oven dry, put into mortar, grind into powder, cross 180 order fine powders, standby;
(3) Herba Saussuseae Japonicae, Radix Dendropanacis and Neolepisorus ovatus (Bedd.) Ching. are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 ℃ of simmer down tos, relative density is 1.12~1.16 is standby;
(4) Folium Musae and Semen Ginkgo are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(5) above-mentioned steps (1)~(4) prepared thick paste, fine powder and juice are mixed, make capsule, obtain the Chinese medicine preparation that is exclusively used in preoperative anesthesia of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Cortex Melaleucae leucadendrae: acrid in the mouth, slightly warm in nature, flat.Fragrance induces sweat, wind-expelling pain-stopping.For cold, fever, rheumatic arthritis, neuralgia, enteritis, diarrhea, allergic dermatitis is controlled in external, and eczema is calmed the nerves, neurasthenia, insomnia.
Nidus Vespae: sweet in the mouth, property is flat; Return stomach warp.Removing the necrotic tissue and promoting granulation, anti-inflammatory analgetic, antiallergic.Applicable toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot, allergic constitution.Modern medicine study confirmation, Nidus Vespae preparation has the effect that promotes Immune Function.
Herba Saussuseae Japonicae: acrid in the mouth, hardship, property is flat.Expelling wind and activating blood circulation.Dispelling the wind and dampness pathogens arthralgia pain, traumatic injury, leprosy.< < decoction pieces is newly joined > > and is carried: " promoting blood circulation by removing wind, loose numbness pain relieving.”
Radix Dendropanacis: sweet in the mouth, warm in nature.Expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.For migraine, brachial plexus neuritis, rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lambago and skelalgia, hemiplegia, traumatic injury, bruise; External is controlled on cutter hemorrhage.< < Zhejiang conventional medical herbs > > among the people carries: " expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, pain relieving.”
Poria: sweet in the mouth, light, property is flat.Promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, relieves internal heat anticancer.Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.Modern medicine study confirmation, the contained pachymic acid of Poria has the effect of enhancing immunity, antitumor and calmness, blood sugar lowering etc., the gastrointestinal smooth muscle that can relax, gastric acid secretion inhibiting, prevents hepatic necrosis, and has antibacterial action.
Folium Artemisiae Argyi: acrid in the mouth, hardship, warm in nature; Return liver,spleen,kidney warp.Dispersing cold for relieving pain, warming the meridian for stopping bleeding, Li Yin gas, granulation promoting meat, wards off wind and cold.Modern medicine study confirmation, the main component of Folium Artemisiae Argyi all has antibacterial action to 10 kinds of Gram-positive aerophils such as anthrax bacillus, Alpha-hemolytic streptococcus, B-Streptococcus hemolyticus, diphtheria corynebacterium, bacillus pseudodiphthericus, lung diplococcoid, staphylococcus aureus, Staphylococcus citreus, white Portugal Portugal coccus, bacillus subtilis.
Radix achyranthis asperae (Herba Achyranthis Asperae): bitter in the mouth, pungent, cold in nature; Return liver, lung urinary bladder channel.Blood circulation promoting and blood stasis dispelling, clearing away heat and expelling pathogen in the exterior.The heating that cures cold, dysentery, malaria, laryngalgia, beriberi, gonorrhea.Edema, traumatic injury.< < Guangxi Chinese medicinal herbal > > carries: " diuresis, purifies the blood, sterilization.Control red-white dysentery, larynx disease, traumatic injury, strengthening bone and muscle, loose blood, pain relieving, reason beriberi.”
Herba sedi kamtschatici: sour in the mouth, property is flat.Promoting blood circulation and hemostasis, mind calming dampness removing, subduing swelling and detoxicating.Control traumatic injury, hemoptysis, spits blood, have blood in stool, and cardiopalmus, carbuncle.< < Fujian traditional herbal medicine > > carries: " subduing the hyperfunction of the liver mind calming, clearing away heat from blood are treated cardiopalmus.”
Folium Musae: sweet in the mouth, light, cold in nature; GUIXIN, Liver Channel.Heat clearing away, diuresis, removing toxic substances.Control calentura, heatstroke, beriberi, carbuncle pyretic toxicity, scalds.< < book on Chinese herbal medicine newer > > carries: " control heart-fire and burn, liver hot air wind producing, relieving restlessness expelling summer-heat.”
Herba Xanthii: bitter in the mouth, pungent, cold nature, slightly poisonous; Return lung meridian.Wind and heat eliminating, removing toxic substances parasite killing, loose wind dehumidifying, understand things pain-stopping.Cure mainly flu, wind syndrome of head, dizziness, nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture is numb, wind leprosy, furuncle, scabies, skin pruritus, hemorrhoid, dysentery.< < herbal classic > > carries: " spasm of the limbs pain, dislikes the dead mark of meat for the cold pain of main air head, rheumatism general arthralgia.”
Caulis Polygoni Multiflori: sweet in the mouth, micro-hardship; Enter the heart, Liver Channel.Tranquilizing by nourishing the heart, dredging collateral dispels the wind.Cure mainly insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.< < Shaanxi Chinese herbal medicine > > carries: " wind-damp dispelling, the meridian dredging.Control head and sleep, hyperhidrosis, anemia, malasia, the dermatosiss such as scabies.”
Semen Viciae fabae: sweet in the mouth, micro-pungent, property is flat; Return spleen, stomach, heart channel.Invigorating spleen for diuresis, removing toxic substances and promoting subsidence of swelling.Main diaphragm food, edema, sore.< < Hunan medicine will > > carries; " spleen invigorating, hemostasis, diuresis.”
Herba Salomoniae Cantoniensis: taste is micro-pungent, property is flat; GUIXIN, Liver Channel.Removing toxic substances and promoting subsidence of swelling, eliminating stasis to stop pain.Main carbuncle skin infection, innominate toxic swelling, sore throat, venom, traumatic injury, rheumatic arthritis, toothache.< < GUIHAIA register > > carries: " removing toxic substances, detumescence, pain relieving.Control venom, innominate toxic swelling.”
Radix Angelicae Pubescentis: acrid in the mouth, hardship, slightly warm in nature; Return liver, kidney, urinary bladder channel.Modern medicine study confirmation, Radix Angelicae Pubescentis has antiinflammatory, analgesia and sedation.
Semen Ginkgo: sweet in the mouth, hardship, puckery, property is flat, poisonous; Return lung meridian.Astringing lung QI for relieving asthma, leukorrhagia stopping is turbid, urine reducing.For abundant expectoration, breath with cough, leukorrhagia nebulousurine, enuresis frequent micturition.< < book on Chinese herbal medicine newer > > carries: " QI invigorating nourishes heart, kidney tonifying YIN nourishing, and cough-relieving relieving restlessness, granulation promoting is put on flesh, and evacuation of pus is drawn out pus by applying a plaster to the affected part, the skin ulcer that disappears scabies cellulitis tumor.”
Neolepisorus ovatus (Bedd.) Ching.: bitter in the mouth, cool in nature; GUIXIN, lung, urinary bladder channel.Clearing away heat-damp and promoting diuresis, cooling blood for hemostasis.For urinary tract infection, dysuria, spitting of blood.Wound hemorrhage is controlled in external, burn and scald.
The present invention compared with prior art, has following beneficial effect:
The selected high-quality Chinese crude drug of Chinese medicine preparation of the present invention compatibility, meet Chinese medicine and pharmacy and modern medicine theory, be applicable to local anesthesia and general anesthesia, there is antishock effect, easy to use, safe and reliable, in clinical practice, there is very significant anaesthetic effect, can apply the narcotic analgesic with various clinical operations, wide popularization and application on clinic.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) Cortex Melaleucae leucadendrae, Poria, Folium Artemisiae Argyi, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba sedi kamtschatici, Herba Xanthii, Caulis Polygoni Multiflori, Herba Salomoniae Cantoniensis and Radix Angelicae Pubescentis are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) by Nidus Vespae and Semen Viciae fabae decontamination, after oven dry, put into mortar, grind into powder, cross 180 order fine powders, standby;
(3) Herba Saussuseae Japonicae, Radix Dendropanacis and Neolepisorus ovatus (Bedd.) Ching. are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 ℃ of simmer down tos, relative density is 1.12~1.16 is standby;
(4) Folium Musae and Semen Ginkgo are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(5) above-mentioned steps (1)~(4) prepared thick paste, fine powder and juice are mixed, make capsule, obtain the Chinese medicine preparation that is exclusively used in preoperative anesthesia of the present invention.
Usage and dosage: oral, perform the operation and take for first 10 minutes, each 1, after 10 minutes, can perform a surgical operation.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation that is exclusively used in preoperative anesthesia, select clinical operation patient 304 routine clinical observations, patient is divided into two groups of experimental group and matched groups at random, experimental group 152 examples, male's 76 examples wherein, women's 76 examples, 21~64 years old age, 42.5 years old mean age; Matched group 152 examples, male's 76 examples wherein, women's 76 examples, 20~63 years old age, 41.5 years old mean age.
The course of disease, the degrees of symptoms of experimental group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Experimental group is taken Chinese medicine preparation of the present invention, oral, performs the operation and takes for first 10 minutes, each 1, after 10 minutes, can perform a surgical operation.
Matched group injection procaine, injection, with its 3~4% solution, calculates the 0.75g that is no more than per hour by hydrochlorate.
3, efficacy determination:
Effective: painless in operation process, the appearance that has no adverse reaction in art, postoperative no sequel, the appearance that has no side effect, operation is well on.
Invalid: in operation process, there is pain, or in art, occur untoward reaction, or postoperative sequela, there is certain side effect to occur.
4, concrete outcome is as following table:
Above result demonstration, the anaesthetic effect of Chinese medicine preparation of the present invention is apparently higher than the selected anaesthetic of matched group.
Model case is given an example:
1, model, man, 24 years old, Chongqing Jiangbei people from district.Clavus is suffered from for many years in patient's left foot outside, walks extremely uncomfortable, need perform the operation and excavate, and uses Chinese medicine preparation treatment of the present invention, takes after 1 time, after 10 minutes, performs the operation, painless in art.
2, stone, female, 31 years old, people from Fushun.Patient's upper arm scratches, and the about 3cm of wound carries out, after preliminary hemostasis processing, need carrying out further sewing up and processing.Use Chinese medicine preparation treatment of the present invention, take after 1 time, after 10 minutes, sew up, painless in art.
3, Yao, man, 45 years old, Huainan, Anhui people.Patient suffers from external piles 5 years, and through repeatedly excision, in July, 2008, recurrence, need carry out operative treatment.Use Chinese medicine preparation of the present invention treatment, take after 1 time, perform the operation after 10, painless in art, within postoperative 4 hours, recover pain.
4, Tan, female, 28 years old, Sanming, Fujian Province people.There is a lump patient's right breast inner side, need excise.Use Chinese medicine preparation treatment of the present invention, take after 1 time, after 10 minutes, perform the operation, painless, after postoperative 3 hours, recover pain, appearance has no side effect.
5, Liao, man, 30 years old, Heilungkiang grand celebration people.Patient's femur head necrosis, need carry out Wicresoft's acicular hook and dial loose art treatment.Use Chinese medicine preparation treatment of the present invention, take after 1 time, after 10 minutes, carry out Wicresoft's acicular hook and dial loose art operation, painless, after postoperative 4 hours, recover pain, without postoperative sequela, occur.
6, Xiong, female, 41 years old, Tonghua, Jilin Province people.Clavus is suffered from for many years in patient's left foot outside, walks extremely uncomfortable, need perform the operation and excavate.Use Chinese medicine preparation treatment of the present invention, take after 1 time, after 10 minutes, perform the operation, painless in art.
Claims (5)
1. a Chinese medicine preparation that is exclusively used in preoperative anesthesia, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
28~52 parts of 28~52 parts of Radix Dendropanacis of 29~53 parts of Herba Saussuseae Japonicaes of 31~55 parts of Nidus Vespae of Cortex Melaleucae leucadendrae
25~49 parts of 26~50 parts of Herba sedi kamtschatici of 26~50 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s of 27~51 portions of Folium Artemisiae Argyis of Poria
22~46 parts of 22~46 parts of Semen Viciae fabaes of 23~47 parts of Caulis Polygoni Multiflori of 25~49 portions of Herba Xanthiis of Folium Musae
16~40 parts of 19~43 parts of Neolepisorus ovatus (Bedd.) Ching.s of 19~43 portions of Semen Ginkgoes of 20~44 parts of Radix Angelicae Pubescentiss of Herba Salomoniae Cantoniensis.
2. a kind of Chinese medicine preparation that is exclusively used in preoperative anesthesia according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
32~48 parts of 32~48 parts of Radix Dendropanacis of 33~49 parts of Herba Saussuseae Japonicaes of 35~51 parts of Nidus Vespae of Cortex Melaleucae leucadendrae
29~45 parts of 30~46 parts of Herba sedi kamtschatici of 30~46 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s of 31~47 portions of Folium Artemisiae Argyis of Poria
26~42 parts of 26~42 parts of Semen Viciae fabaes of 27~43 parts of Caulis Polygoni Multiflori of 29~45 portions of Herba Xanthiis of Folium Musae
20~36 parts of 23~39 parts of Neolepisorus ovatus (Bedd.) Ching.s of 23~39 portions of Semen Ginkgoes of 24~40 parts of Radix Angelicae Pubescentiss of Herba Salomoniae Cantoniensis.
3. a kind of Chinese medicine preparation that is exclusively used in preoperative anesthesia according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
36~44 parts of 36~44 parts of Radix Dendropanacis of 37~45 parts of Herba Saussuseae Japonicaes of 39~47 parts of Nidus Vespae of Cortex Melaleucae leucadendrae
33~41 parts of 34~42 parts of Herba sedi kamtschatici of 34~42 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s of 35~43 portions of Folium Artemisiae Argyis of Poria
30~38 parts of 30~38 parts of Semen Viciae fabaes of 31~39 parts of Caulis Polygoni Multiflori of 33~41 portions of Herba Xanthiis of Folium Musae
24~32 parts of 27~35 parts of Neolepisorus ovatus (Bedd.) Ching.s of 27~35 portions of Semen Ginkgoes of 28~36 parts of Radix Angelicae Pubescentiss of Herba Salomoniae Cantoniensis.
4. a kind of Chinese medicine preparation that is exclusively used in preoperative anesthesia according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
40 parts of 40 parts of Radix Dendropanacis of 41 parts of Herba Saussuseae Japonicaes of 43 parts of Nidus Vespae of Cortex Melaleucae leucadendrae
37 parts of 38 parts of Herba sedi kamtschatici of 38 parts of Radix achyranthis asperae (Herba Achyranthis Asperae)s of 39 portions of Folium Artemisiae Argyis of Poria
34 parts of 34 parts of Semen Viciae fabaes of 35 parts of Caulis Polygoni Multiflori of 37 portions of Herba Xanthiis of Folium Musae
28 parts of 31 parts of Neolepisorus ovatus (Bedd.) Ching.s of 31 portions of Semen Ginkgoes of 32 parts of Radix Angelicae Pubescentiss of Herba Salomoniae Cantoniensis.
5. a preparation method for the Chinese medicine preparation that is exclusively used in preoperative anesthesia as described in claim 1~4 any one, is characterized in that: comprise following processing step:
(1) Cortex Melaleucae leucadendrae, Poria, Folium Artemisiae Argyi, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba sedi kamtschatici, Herba Xanthii, Caulis Polygoni Multiflori, Herba Salomoniae Cantoniensis and Radix Angelicae Pubescentis are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) by Nidus Vespae and Semen Viciae fabae decontamination, after oven dry, put into mortar, grind into powder, cross 180 order fine powders, standby;
(3) Herba Saussuseae Japonicae, Radix Dendropanacis and Neolepisorus ovatus (Bedd.) Ching. are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 ℃ of simmer down tos, relative density is 1.12~1.16 is standby;
(4) Folium Musae and Semen Ginkgo are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(5) above-mentioned steps (1)~(4) prepared thick paste, fine powder and juice are mixed, make capsule, obtain the Chinese medicine preparation that is exclusively used in preoperative anesthesia of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410240604.3A CN103977165A (en) | 2014-06-01 | 2014-06-01 | Traditional Chinese medicine preparation dedicated to anesthesia before operation and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410240604.3A CN103977165A (en) | 2014-06-01 | 2014-06-01 | Traditional Chinese medicine preparation dedicated to anesthesia before operation and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103977165A true CN103977165A (en) | 2014-08-13 |
Family
ID=51269492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410240604.3A Pending CN103977165A (en) | 2014-06-01 | 2014-06-01 | Traditional Chinese medicine preparation dedicated to anesthesia before operation and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103977165A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104274627A (en) * | 2014-11-02 | 2015-01-14 | 颜政 | Special traditional Chinese medicine anesthetic for surgery and preparation method thereof |
| CN104435503A (en) * | 2014-12-13 | 2015-03-25 | 于全生 | Traditional Chinese medicine anesthetic special for pre-operation and preparation method |
| CN104524056A (en) * | 2014-12-12 | 2015-04-22 | 李英霞 | Medicament for local anesthesia and analgesia and preparation method of medicament |
| CN104998215A (en) * | 2015-08-18 | 2015-10-28 | 密夫丽 | Medicine for general anesthesia and preparation method of medicine |
| CN104998081A (en) * | 2015-08-28 | 2015-10-28 | 济南舜昊生物科技有限公司 | Medicine for general anesthesia and preparation method thereof |
| CN105012803A (en) * | 2015-08-05 | 2015-11-04 | 朱伟波 | Traditional Chinese medicine preparation for preoperative anesthesia and preparation method of traditional Chinese medicine preparation |
| CN105616992A (en) * | 2016-02-01 | 2016-06-01 | 牟爱珍 | Medicine for anesthesia and relieving pain and preparation method thereof |
-
2014
- 2014-06-01 CN CN201410240604.3A patent/CN103977165A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 侯士良主编: "《中药八百中详解》", 31 January 2009, 河南科学技术出版社 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104274627A (en) * | 2014-11-02 | 2015-01-14 | 颜政 | Special traditional Chinese medicine anesthetic for surgery and preparation method thereof |
| CN104524056A (en) * | 2014-12-12 | 2015-04-22 | 李英霞 | Medicament for local anesthesia and analgesia and preparation method of medicament |
| CN104524056B (en) * | 2014-12-12 | 2018-09-18 | 李英霞 | A kind of medicament of regional anesthesia analgesia and preparation method thereof |
| CN104435503A (en) * | 2014-12-13 | 2015-03-25 | 于全生 | Traditional Chinese medicine anesthetic special for pre-operation and preparation method |
| CN105012803A (en) * | 2015-08-05 | 2015-11-04 | 朱伟波 | Traditional Chinese medicine preparation for preoperative anesthesia and preparation method of traditional Chinese medicine preparation |
| CN104998215A (en) * | 2015-08-18 | 2015-10-28 | 密夫丽 | Medicine for general anesthesia and preparation method of medicine |
| CN104998081A (en) * | 2015-08-28 | 2015-10-28 | 济南舜昊生物科技有限公司 | Medicine for general anesthesia and preparation method thereof |
| CN105616992A (en) * | 2016-02-01 | 2016-06-01 | 牟爱珍 | Medicine for anesthesia and relieving pain and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103977165A (en) | Traditional Chinese medicine preparation dedicated to anesthesia before operation and preparation method thereof | |
| CN103520555B (en) | Drug for treatment of migraine | |
| CN102078527A (en) | Traditional Chinese medicine formula for treating urinary calculus | |
| CN101732522B (en) | Plaster for treating osteonecrosis of the femoral head, osseous tuberculosis, osteomyelitis and osteoma | |
| CN103877454A (en) | Chinese traditional medicine plaster special for local anaesthesia and analgesia and preparation method of plaster | |
| CN103705791B (en) | Medicament for clinical anesthesia and preparation method thereof | |
| CN103721006A (en) | Traditional Chinese medicinal anesthetic and preparation method thereof | |
| CN103211990A (en) | Chinese medicinal composition for treating oral ulcer | |
| CN104958581A (en) | Chinese herbal preparation for treating epifolliculitis and preparing method of Chinese herbal preparation for treating epifolliculitis | |
| CN103830425B (en) | Traditional Chinese medicine for treating blood deficiency type skin itch | |
| CN105012803A (en) | Traditional Chinese medicine preparation for preoperative anesthesia and preparation method of traditional Chinese medicine preparation | |
| CN105213662A (en) | A kind of Chinese medicine composition promoting surgical wounds healing and ease the pain | |
| CN105362456A (en) | Oral medicine for treating early stage cervical cancer and preparation method thereof | |
| CN104352667A (en) | Medicine for treating nonspecific vaginitis and preparation method | |
| CN103751624B (en) | A kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy | |
| CN104189608B (en) | Traditional Chinese medicine preparation for recurrent oral ulcer and preparation method thereof | |
| CN102949544A (en) | Chinese medicinal composition for specifically treating swelling of hands and feet of hemiplegic patients | |
| CN104274627A (en) | Special traditional Chinese medicine anesthetic for surgery and preparation method thereof | |
| CN104367733A (en) | Traditional Chinese medicine anesthetic for tooth pulling surgery and preparation method thereof | |
| CN105031110A (en) | Traditional Chinese medicine plaster for treating cervical spondylosis and preparation method thereof | |
| CN104547447A (en) | Traditional Chinese medicine liquid for treating adverse reaction of anesthetic and preparation method of traditional Chinese medicine liquid | |
| CN105412484A (en) | Medicine for treating arthralgia, and preparation method thereof | |
| CN106038879A (en) | Traditional Chinese medicine plaster for treating cervical spondylosis and preparation method | |
| CN103977296A (en) | Traditional Chinese medicine oral solution for treating urethritis and preparation method thereof | |
| CN105902670A (en) | Medicine used for traumatic hairline fracture and preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140813 |
|
| RJ01 | Rejection of invention patent application after publication |