CN103961558A - Dendrobium candidum instant granule for alleviating hangover and protecting liver - Google Patents
Dendrobium candidum instant granule for alleviating hangover and protecting liver Download PDFInfo
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Abstract
The invention discloses a dendrobium candidum instant granule for alleviating hangover and protecting a liver, and belongs to the field of traditional Chinese medicines. The dendrobium candidum instant granule is characterized by comprising the following raw materials in parts by weight: 20-40 parts of dendrobium candidum, 10-15 parts of pueraria flower, 20-40 parts of fried hawthorn, 10-20 parts of hericium erinaceus, 10-20 parts of grifola and 5-10 parts of dried orange peel. The dendrobium candidum instant granule can quickly alleviate hangover, has an efficacy of reducing physical discomfort after drinking, can protect the liver, and protects gastric mucosa from damage. The dendrobium candidum instant granule is convenient to dissolve, high in absorption speed, and free of toxic and side effects.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver.
Background technology
Drink is during people live, to practise the empty one activity of being used to of seeing, on every festival, moving to a better place, celebration, birthday, wedding etc. all be unable to do without adds to the fun with wine, in social occasion, drink and be a kind of means of interpersonal distance of furthering, be braiding and the important channel of building social relations net.Along with China market expanding economy, the increased and social dinner party of business activity increases gradually, and heavy drinking causes uncomfortable and to affect the healthy situation of alcohol user of common occurrence.
Medically, by the drunk acute alcoholism that is called, alcoholism can seriously destroy neural normal function; Long-term excessive drinking forms chronic alcoholism, and infringement liver, can cause the diseases such as alcoholic cirrhosis, polyneuritis, cardiomyopathy, cerebral lesion, hematopoietic disorder, pancreatitis, gastritis and stain infections; Also can make the sickness rate of hypertension raise; In addition, also endanger sexual cell, cause offspring's mental retardation etc.
For the ill symptoms that prevents from producing after drinking; people start with from natural Chinese medicinal herb; utilize the intrinsic antialcoholism action of some Chinese herbal medicine itself; develop multiple sobering preparation; though these sobering preparations have certain effects of relieving alcoholism and preventing drunkenness; protect the liver the liver benefiting but lack in preparation, the composition of the multiple efficacies such as protection gastric mucosa.
Summary of the invention
The object of the invention is to: for the problem of above-mentioned existence; a kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is provided; not only have and can relieve the effect of alcohol fast, alleviate effect uncomfortable after drinking, and can in relieving the effect of alcohol, hepatoprotective the liver benefiting, protection gastric mucosa lack damaged.Instant granular of the present invention not only reconstitutes conveniently, absorbs soon, and has no side effect.
The technical solution used in the present invention is as follows:
A dendrobium candidum instant granule for relieving alcoholism and protecting the liver, is characterized in that being made up of the former medicine of following weight portion: 20～40 parts of Herba Dendrobii, 10～15 parts of Flos puerariae lobataes, 20～40 parts of Fructus Crataegi (parched), 10～20 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 10～20 parts of Polyporus, 5～15 parts of Pericarpium Citri Reticulataes.
Preferably, made by the former medicine of following weight portion: 25～35 parts of Herba Dendrobii, 12～14 parts of Flos puerariae lobataes, 18～25 parts of Fructus Crataegi (parched), 12～18 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 12～18 parts of Polyporus, 8～12 parts of Pericarpium Citri Reticulataes.
Preferably, made by the former medicine of following weight portion: 30 parts of Herba Dendrobii, 13 parts of Flos puerariae lobataes, 20 parts of Fructus Crataegi (parched), 15 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 15 parts of Polyporus, 10 parts of Pericarpium Citri Reticulataes.
Described Herba Dendrobii is Herba Dendrobii dry product.
The preparation technology that a kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is provided, comprises the following steps:
(1) take Herba Dendrobii, Flos puerariae lobatae, Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers., Polyporus, Pericarpium Citri Reticulatae as raw material of Chinese medicine by formula proportion.
(2) Flos puerariae lobatae, Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers., Polyporus, Pericarpium Citri Reticulatae mixing are put into baking oven and toasted 6-8 hour, open baking oven and be chilled to natural temperature, pulverizing was the mixed powder of 120 mesh sieves;
(3) to adding water logging half an hour in Herba Dendrobii, then decoct 2-4 time, filter, merge each filtrate;
(4) add white sugar, citric acid to filtrate, stir and make its dissolving; The amount that adds white sugar is the 5-10% of mixed powder quality, and the amount of adding citric acid is the 0.03-0.08% of mixed powder quality;
(5) filtrate that is dissolved with white sugar, citric acid is added in mixed powder, stirs, adding water and being adjusted to the moisture mass percent of medicated powder is 40-45%, move to oven for drying and in the time that moisture is less than 5%, stop heating, naturally cooling, puts into granulation machine pelletize, obtains instant granular;
Baking temperature in described step (2) is 50-65 DEG C.
Amount of water in described step (3) is 10 times of Herba Dendrobii gross mass.
In described step (5), the baking temperature of baking oven is 40-60 DEG C.
Herba Dendrobii involved in the present invention, its role is to, and 1) nourishing the stomach hepatoprotective relieves the effect of alcohol: Compendium of Material Medica is recorded, Herba Dendrobii abnormal smells from the patient: sweet, flat, nontoxic, cure mainly: damaging the spleen and stomach, the eliminating impediment therapeutic method to keep the adverse QI flowing downwards, tonifying five ZANG-organs asthenia weakness and emaciation, reinforcing YIN-essence benefit essence, clothes for a long time, thick the intestines and stomach, herbal classic is never sufficient in mending, flat gastric qi, longue meat, the kidney invigorating benefit power, warming the kidney, Fructus Alpiniae Oxyphyllae clearing heat in QI system, solar corona is controlled heating spontaneous perspiration, plug in carbuncle evacuation of pus.Herba Dendrobii has the function of tonifying five ZANG-organs, thick the intestines and stomach, reinforcing YIN-essence benefit essence, Herba Dendrobii contains abundant polysaccharose substance, after edible, produce a kind of protecting film at stomach, reduce the destruction of ethanol to stomach, strengthen the metabolic function of liver simultaneously, by being in harmonious proportion in body, alcoholic strength is dissolved, allow drunk people recover very fast; 2) strengthen the spleen and stomach: Herba Dendrobii is reinforcing stomach reg fluid medicine, all on the books in Shennong's Herbal, " book on Chinese herbal medicine is new again ", appellation " medicine for enterogastritis ", is the common drug that treatment gastric abscess, upper abdomen go up painful.Modern medicine experiment confirms: Herba Dendrobii has good inhibitory action to pathogenic bacterium helicobacter pylori common in the spleen-stomach disease, contributes to treat the effect of the Helicobacter pylori diseases such as atrophic gastritis, superficial gastritis, duodenal ulcer.
Flos puerariae lobatae, sweet in the mouth, cool in nature, enter sufficient Yangming Channel, energy relieving acute alcoholism and recuperating the spleen; There is the wine of curing the wound heating excessive thirst, anorexia, vomiting acid regurgitation, spits blood, effect of discharging fresh blood stool.Saponin in Flos puerariae lobatae, osajin has redox, and acceleration of alcohol oxidation, can make ethanol lose toxicity; Shrink and protection gastrointestinal mucosa, slow down the absorption of ethanol, enter blood circulation hindered alcohol rapid, high volume; Intoxicating material in the adsorbable wine of osajin in Flos puerariae lobatae, reduces alcohol concentration, reduces myocardial oxygen consumption, protection cardiovascular, and by accelerations urinate, perspire, excretion decomposing alcohol, alleviate the uncomfortable symptom such as have a headache, dizzy, nauseating, alleviate drunk degree.
Fructus Crataegi (parched), slightly warm in nature, sour in the mouth, sweet; Return spleen, stomach, Liver Channel.There is appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, effect of promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm.
Hericium erinaceus (Bull. Ex Fr.) Pers., property is flat, and sweet in the mouth, obtains the five internal organs, contains a large amount of protein, fat, carbohydrate, aminoacid and multivitamin, can strengthen body immunity, can treat the diseases such as dyspepsia, stomach stain infections, antral gastritis, stomachache, flatulence and neurasthenia.
Polyporus, sweet in the mouth, light, property is flat, returns kidney, urinary bladder channel.There is effect of promoting diuresis to eliminate damp pathogen.
Pericarpium Citri Reticulatae bitter in the mouth, pungent, temperature.Return lung, spleen channel.Pericarpium Citri Reticulatae contains the compositions such as volatile oil, hesperidin, vitamin B, C, and its contained volatile oil has gentle stimulation to gastrointestinal tract, and pneumatosis in intestinal tube is got rid of in secretion that can facilitating digestion liquid, increases appetite.Pericarpium Citri Reticulatae is also conventional Chinese medicine simply, has the greasy lasting of spleen invigorating, drying dampness to eliminate phlegm, solution of ventilation, effect of stopping nausea and vomiting by lowering the adverse flow of QI.
The elite of the succession traditional Chinese medical science, the dendrobium candidum instant granule prescription pharmacology of a kind of relieving alcoholism and protecting the liver of the present invention is: relieve the effect of alcohol, protect the liver, diuresis, strengthening the spleen and stomach.Above-mentioned prescription, scientific and reasonable compatibility, follow " monarch, minister, help, make " principle, Herba Dendrobii taking Antialcoholic liver-protecting as master and Flos puerariae lobatae are as principal agent, taking the Polyporus of diuresis eliminating dampness by diuresis as accessory drugs, and assistant is with Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers., the Pericarpium Citri Reticulatae of appetite promoting and the spleen strengthening, by the reasonable compatibility of 6 taste Chinese herbal medicine, realize the pharmacological function effect of Dealcoholic sobering-up, liver-protecting and stomach-protecting, diuresis toxin expelling, appetite promoting and the spleen strengthening, to reach the object for the treatment of.
Usage and dosage: take after mixing it with hot water after drinking, each 20g, after clothes, half an hour is according to the continuous clothes of drunk person's symptom, each 10-20g.
Beneficial effect of the present invention: relieve the effect of alcohol rapidly, the effect of relieving the effect of alcohol is remarkable, protects the liver, strengthening the spleen and stomach, the toxic removing of relieving the effect of alcohol, and effective percentage reaches 100%, and prescription is simple, draws materials easily, easy to carry; Can be used for all insobriety persons.
Detailed description of the invention
The invention provides a kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver, made by the former medicine of following weight portion: 20～40 parts of Herba Dendrobii, 10～15 parts of Flos puerariae lobataes, 20～40 parts of Fructus Crataegi (parched), 10～20 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 10～20 parts of Polyporus, 5～15 parts of Pericarpium Citri Reticulataes.
In some embodiments of the invention, made by the former medicine of following weight portion: 25～35 parts of Herba Dendrobii, 12～14 parts of Flos puerariae lobataes, 18～25 parts of Fructus Crataegi (parched), 12～18 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 12～18 parts of Polyporus, 8～12 parts of Pericarpium Citri Reticulataes.
In some embodiments of the invention, made by the former medicine of following weight portion: 30 parts of Herba Dendrobii, 13 parts of Flos puerariae lobataes, 20 parts of Fructus Crataegi (parched), 15 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 15 parts of Polyporus, 10 parts of Pericarpium Citri Reticulataes.
Wherein, described Herba Dendrobii is Herba Dendrobii dry product.
The preparation technology that a kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is provided, comprises the following steps:
(1) take Herba Dendrobii, Flos puerariae lobatae, Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers., Polyporus, Pericarpium Citri Reticulatae as raw material of Chinese medicine by formula proportion.
(2) Flos puerariae lobatae, Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers., Polyporus, Pericarpium Citri Reticulatae mixing are put into baking oven and toasted 6-8 hour, open baking oven and be chilled to natural temperature, pulverizing was the mixed powder of 120 mesh sieves;
(3) to adding water logging half an hour in Herba Dendrobii, then decoct 2-4 time, filter, merge each filtrate;
(4) add white sugar, citric acid to filtrate, stir and make its dissolving; The amount that adds white sugar is the 5-10% of mixed powder quality, and the amount of adding citric acid is the 0.03-0.08% of mixed powder quality;
(5) filtrate that is dissolved with white sugar, citric acid is added in mixed powder, stirs, adding water and being adjusted to the moisture mass percent of medicated powder is 40-45%, move to oven for drying and in the time that moisture is less than 5%, stop heating, naturally cooling, puts into granulation machine pelletize, obtains instant granular;
In some embodiments of the invention, the baking temperature in described step (2) is 50-65 DEG C.
In some embodiments of the invention, the amount of water in described step (3) is 10 times of Herba Dendrobii gross mass.
In some embodiments of the invention, in described step (5), the baking temperature of baking oven is 40-60 DEG C.
Below in conjunction with embodiment, the present invention is described in further detail:
Embodiment 1
A kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is made up of the former medicine of following weight portion: 30 parts of Herba Dendrobii, 13 parts of Flos puerariae lobataes, 20 parts of Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers. 15,15 parts of Polyporus, 10 parts of Pericarpium Citri Reticulataes.
Embodiment 2
A kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is made up of the former medicine of following weight portion: 20 parts of Herba Dendrobii, 15 parts of Flos puerariae lobataes, 40 parts of Fructus Crataegi (parched), 20 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 10 parts of Polyporus, 12 parts of Pericarpium Citri Reticulataes.
Described Herba Dendrobii is Herba Dendrobii dry product.
Embodiment 3
A kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is made up of the former medicine of following weight portion: 25 parts of Herba Dendrobii, 14 parts of Flos puerariae lobataes, 25 parts of Fructus Crataegi (parched), 12 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 18 parts of Polyporus, 8 parts of Pericarpium Citri Reticulataes.
Embodiment 4
A kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is made up of the former medicine of following weight portion: 35 parts of Herba Dendrobii, 10 parts of Flos puerariae lobataes, 20 parts of Fructus Crataegi (parched), 10 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 20 parts of Polyporus, 15 parts of Pericarpium Citri Reticulataes.
Embodiment 5
A kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is made up of the former medicine of following weight portion: 40 parts of Herba Dendrobii, 12 parts of Flos puerariae lobataes, 18 parts of Fructus Crataegi (parched), 18 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 12 parts of Polyporus, 5 parts of Pericarpium Citri Reticulataes.
Embodiment 6
The preparation technology that above-described embodiment all adopts, comprises the following steps:
The preparation technology that a kind of dendrobium candidum instant granule of relieving alcoholism and protecting the liver is provided, comprises the following steps:
(1) take Herba Dendrobii, Flos puerariae lobatae, Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers., Polyporus, Pericarpium Citri Reticulatae as raw material of Chinese medicine by formula proportion.
(2) Flos puerariae lobatae, Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers., Polyporus, Pericarpium Citri Reticulatae are mixed and put into baking oven, at the temperature of 50-65 DEG C, toast 6-8 hour, open baking oven and be chilled to natural temperature, pulverizing was the mixed powder of 120 mesh sieves;
(3) to adding water logging half an hour in Herba Dendrobii, amount of water is 10 times of Herba Dendrobii gross mass, then decocts 2-4 time, filters, and merges each filtrate;
(4) add white sugar, citric acid to filtrate, stir and make its dissolving; The amount that adds white sugar is the 5-10% of mixed powder quality, and the amount of adding citric acid is the 0.03-0.08% of mixed powder quality;
(5) filtrate that is dissolved with white sugar, citric acid is added in mixed powder; stir; adding water and being adjusted to the moisture mass percent of medicated powder is 40-45%; move to baking oven; at the temperature of 40-60 DEG C, dry and in the time that moisture is less than 5%, stop heating; naturally cooling, puts into granulation machine pelletize, obtains instant granular.
Experimental data
1, the effect of relieving the effect of alcohol
Select 50 insobriety persons with this one alcohol-decomposing powder.In 50 routine insobriety persons, male 45 people, account for 90%; Female, 5 people, account for 10%; At wherein maximum 67 years old age, minimum 16 years old, the age, 46 people in 18-50 year, accounted for 92%; The wine degree of drinking is 39-53 °, and drinking amount is 250ml-700ml, half an hour-1.5 hour after drinking, drunk person's symptom: flushed face or pale, or vomiting; Wherein: unconsciousness companioned with headache person 4 people, account for 8%, 5 drowsiness people account for 10%, restlessness, incoherent 8 people, account for 16%.With this one alcohol-decomposing powder 20-40g, after 20-80 minute, recover normal, effective percentage 100%.
Typical case
Liu Wenxing, man, 28 years old, high and new technology industrial development zone, the Nanning City business personnel of pharmaceutcal corporation, Ltd, drinks 53 ° of Chinese liquor 650ml evening on March 25th, 2014, pale complexion after drink, drink latter 40 minutes babbles, nausea and vomiting, after be sunk into sleep, household takes this instant granular 30g that relieves the effect of alcohol for it, after 30 minutes, improving situation, drinks again 20g, recovers normal after 30 minutes.
2, hepatoprotective effect
70 mices, male and female half and half, are divided into 7 groups at random, every group 10, model group is pressed normal saline 0.2ml/10g gastric infusion, 50% alcoholic liver injury positive controls and embodiment 1-5 by instant granular 0.4g/kg gastric infusion, 1 time/d, 10d continuously, gavage volume is 0.2ml/10g; After every day gastric infusion 30min, respectively organize the equal gavage 56 of mice and spend strong, colourless liquor distilled from sorghum Chinese liquor 0.16ml/10g.Can't help water to for the 10th day fasting after drinking, after 24h, weigh, gather liver specimens, do coherent detection.ALT, AST press test kit description colorimetric method for determining, and ALT and the AST concentration in cell is to detect the important indicator of hepar damnification.
With model group comparison: P < 0.05, positive controls and embodiment 1-5 all can effectively reduce the rising of ALT, AST, point out its ALT, the AST that can effectively contain that ethanol causes to raise, and the hepatic injury of drunk mice is had to protective effect.
Claims (8)
1. a dendrobium candidum instant granule for relieving alcoholism and protecting the liver, is characterized in that being made up of the former medicine of following weight portion: 20～40 parts of Herba Dendrobii, 10～15 parts of Flos puerariae lobataes, 20～40 parts of Fructus Crataegi (parched), 10～20 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 10～20 parts of Polyporus, 5～15 parts of Pericarpium Citri Reticulataes.
2. the dendrobium candidum instant granule of a kind of relieving alcoholism and protecting the liver as claimed in claim 1, is characterized in that being made up of the former medicine of following weight portion: 25～35 parts of Herba Dendrobii, 12～14 parts of Flos puerariae lobataes, 18～25 parts of Fructus Crataegi (parched), 12～18 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 12～18 parts of Polyporus, 8～12 parts of Pericarpium Citri Reticulataes.
3. the dendrobium candidum instant granule of a kind of relieving alcoholism and protecting the liver as claimed in claim 1, is characterized in that being made up of the former medicine of following weight portion: 30 parts of Herba Dendrobii, 13 parts of Flos puerariae lobataes, 20 parts of Fructus Crataegi (parched), 15 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 15 parts of Polyporus, 10 parts of Pericarpium Citri Reticulataes.
4. the dendrobium candidum instant granule of a kind of relieving alcoholism and protecting the liver as described in as arbitrary in claim 1～3, is characterized in that: described Herba Dendrobii is Herba Dendrobii dry product.
5. according to the preparation technology of the dendrobium candidum instant granule of a kind of relieving alcoholism and protecting the liver described in claim 1-5, it is characterized in that comprising the following steps:
(1) take Herba Dendrobii, Flos puerariae lobatae, Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers. part, Polyporus, Pericarpium Citri Reticulatae as raw material by formula proportion.
(2) Flos puerariae lobatae, Fructus Crataegi (parched), Hericium erinaceus (Bull. Ex Fr.) Pers., Polyporus, Pericarpium Citri Reticulatae mixing are put into baking oven and toasted 6-8 hour, open baking oven and be chilled to natural temperature, pulverizing was the mixed powder of 120 mesh sieves;
(3) to adding water logging half an hour in Herba Dendrobii, then decoct 2-4 time, filter, merge each filtrate;
(4) add white sugar, citric acid to filtrate, stir and make its dissolving; The amount that adds white sugar is the 5-10% of mixed powder quality, and the amount of adding citric acid is the 0.03-0.08% of mixed powder quality;
(5) filtrate that is dissolved with white sugar, citric acid is added in mixed powder, stirs, adding water and being adjusted to the moisture mass percent of medicated powder is 40-45%; move to oven for drying and in the time that moisture is less than 5%, stop heating; naturally cooling, puts into granulation machine pelletize, obtains instant granular.
6. the preparation technology of the dendrobium candidum instant granule of a kind of relieving alcoholism and protecting the liver according to claim 5, is characterized in that: the baking temperature in described step (2) is 50-65 DEG C.
7. the preparation technology of the dendrobium candidum instant granule of a kind of relieving alcoholism and protecting the liver according to claim 6, is characterized in that: the amount of water in described step (3) is 10 times of Herba Dendrobii gross mass.
8. the preparation technology of the dendrobium candidum instant granule of a kind of relieving alcoholism and protecting the liver according to claim 7, is characterized in that: in described step (5), the baking temperature of baking oven is 40-60 DEG C.
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Application publication date: 20140806 |